Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	Title	#f	T	TVal	Price	Qty	oc	Own	H
7/18/25 18:00	7/16/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yale Catriona	CA	O	Chief De	8	M.d	2,326	36.10	64	211	95	D
7/18/25 18:00	7/16/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yale Catriona	CA	O	Chief De	8	S.d	-2,326	36.10	-64		95	D
7/18/25 16:51	7/17/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Franchi Jean M.	MA	O	CFO	3	S	-339	56.27	-6		68	D
7/18/25 16:30	7/16/25	SNDX	Syndax Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Goldan Keith A.	NY	O	CFO	2	S	-12	2.80	-4		94	D
7/18/25 16:30	7/16/25	SNDX	Syndax Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Metzger Michael A	NY	DO	CEO	1	S	-70	9.29	-8		299	D
7/18/25 16:13	7/16/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Friedman Paul A	PA	D		2	M.dm	10,472	181.32	58	7	843	D
7/18/25 16:13	7/16/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Friedman Paul A	PA	D		2	S.dm	-10,472	181.32	-58		843	D
7/18/25 16:12	7/17/25	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	Reed John C	NJ	O	EVP,Inno	2	S.d	-3,130	70.50	-44		30	D
7/18/25 16:11	7/16/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Taub Rebecca	PA	D		2	M.dm	10,553	181.32	58	5	1,117	D
7/18/25 16:11	7/16/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Taub Rebecca	PA	D		2	S.dm	-10,553	181.32	-58		1,117	D
7/18/25 16:07	7/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Looker Benjamin	MI	O	GC	2	S	-9	1.15	-8		401	D
7/18/25 16:05	7/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Halladay Benjamin	MI	O	CFO	2	S	-8	1.15	-7		474	D
7/18/25 16:05	7/17/25	MRUS	Merus N.V.	P7	Health	Drug	Pharmaceutical Preparations	Silverman Peter B.	P7	O	COO,GC	6	M.dm	6,267	37.98	165		0	D
7/18/25 16:05	7/17/25	MRUS	Merus N.V.	P7	Health	Drug	Pharmaceutical Preparations	Silverman Peter B.	P7	O	COO,GC	6	S.dm	-6,267	37.98	-165	-100	0	D
7/18/25 16:05	7/16/25	PHAT	Phathom Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Breedlove Robert Charles	NJ	O	Principa	1	S	-14	8.36	-2		54	D
7/18/25 16:02	7/17/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Francois Cedric	MA	DO	CEO	4	M.dm	3,535	15.10	234	14	1,882	D
7/18/25 16:02	7/17/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Francois Cedric	MA	DO	CEO	4	S.dm	-3,535	15.10	-234		1,882	D
7/18/25 16:00	7/16/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Watson David O.	MA	O	GC	2	S	-192	19.16	-10		214	D
7/18/25 14:42	7/18/25	CALC	Calcimedica, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Wilson Robert N	CA	D		1	P	13	2.87	5	1	422	D
7/18/25 14:36	7/18/25	CALC	Calcimedica, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Roberts Eric W	CA	DOT	CHIEF BU	6	P.m	63	1.90	33	3	1,011	I
7/18/25 10:38	7/17/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Freeman Kevin D	GA	D		1	P	14	2.90	5	4	148	D
7/17/25 20:51	7/16/25	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	Binder Steven B.	CT	D		4	S.d	-982	4.24	-232		1,007	D
7/17/25 20:46	7/16/25	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	Thomson David	CT	O	EVP Genl	3	S.d	-190	4.53	-42		891	D
7/17/25 18:20	7/15/25	ETNB	89Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Le-Nguyen Quoc	CA	O	See Rema	1	S	-115	11.02	-10		324	D
7/17/25 17:19	7/15/25	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	Kling Douglas F	P7	O	COO	6	M.dm	7,120	11.92	597		44	D
7/17/25 17:19	7/15/25	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	Kling Douglas F	P7	O	COO	6	S.dm	-7,120	11.92	-597		44	D
7/17/25 16:59	7/15/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Loscalzo Joseph	CA	D		1	M.d	0	0.00	4	13	36	D
7/17/25 16:54	7/15/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Yang Michael J.	CA	D		1	M.d	0	0.00	4	211	6	D
7/17/25 16:54	7/15/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Wender Joseph H	CA	D		1	M.d	0	0.00	4	3	137	I
7/17/25 16:54	7/15/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Parshall B Lynne	CA	D		1	M.d	0	0.00	4	5	91	D
7/17/25 16:54	7/15/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Herman Joan E	CA	D		1	M.d	0	0.00	4	10	46	D
7/17/25 16:54	7/15/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Hayden Michael R	CA	D		2	M.d	478	25.05	19	51	56	D
7/17/25 16:53	7/15/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Diaz Allene M.	CA	D		1	M.d	0	0.00	4	26	20	D
7/17/25 16:53	7/15/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Berthelsen Spencer R	CA	D		1	M.d	0	0.00	4	3	156	D
7/17/25 16:32	7/15/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Balcom Alexandra	MA	O	CFO	4	M.dm	4,051	50.64	80		62	D
7/17/25 16:32	7/15/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Balcom Alexandra	MA	O	CFO	4	S.dm	-4,051	50.64	-80		62	D
7/17/25 16:31	7/15/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Porter James Richard	MA	DO	P,CEO	6	M.d	8,193	50.57	162	186	249	D
7/17/25 16:31	7/15/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Porter James Richard	MA	DO	P,CEO	6	S.d	-8,193	50.57	-162		249	D
7/17/25 16:15	7/15/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Hussain Iqbal J	X0	O	GC	8	M.dm	482	10.04	48	76	111	D
7/17/25 16:15	7/15/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Hussain Iqbal J	X0	O	GC	8	S.dm	-482	10.04	-48		111	D
7/17/25 16:10	7/15/25	GBIO	Generation Bio Co.	DE	Health	Drug	Pharmaceutical Preparations	Howze Yalonda	MA	O	GC	1	M.d	0	0.00	3	19	21	D
7/17/25 16:10	7/15/25	GBIO	Generation Bio Co.	DE	Health	Drug	Pharmaceutical Preparations	Conway Kevin John	MA	O	CFO	1	M.d	0	0.00	1	3	18	D
7/17/25 16:10	7/15/25	GBIO	Generation Bio Co.	DE	Health	Drug	Pharmaceutical Preparations	Paone Antoinette	MA	O	COO	1	M.d	0	0.00	2	5	35	D
7/17/25 16:10	7/15/25	GBIO	Generation Bio Co.	DE	Health	Drug	Pharmaceutical Preparations	Samayoa Phillip	MA	O	CHIEF SC	1	M.d	0	0.00	1	1	141	D
7/17/25 16:10	7/15/25	GBIO	Generation Bio Co.	DE	Health	Drug	Pharmaceutical Preparations	McDonough Geoff	MA	DO	P,CEO	1	M.d	0	0.00	5	0	1,866	D
7/17/25 10:40	7/14/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	Moreadith Randall	AL	O	Chief Sc	6	M.d	108	2.77	39		0	D
7/17/25 10:40	7/14/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	Moreadith Randall	AL	O	Chief Sc	6	S.d	-108	2.77	-39	-100	0	D
7/16/25 21:06	7/14/25	MNPR	Monopar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	Tsuchimoto Kim R	IL	D		1	S.d	-356	40.00	-9		11	D
7/16/25 21:03	7/14/25	MNPR	Monopar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	Starr Christopher M	IL	D		1	S.d	-672	40.00	-17		15	D
7/16/25 21:02	7/14/25	MNPR	Monopar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	Robinson Chandler	IL	DO	CEO	2	S.d	-672	22.29	-30		896	D
7/16/25 18:01	7/14/25	TBPH	Theravance Biopharma, Inc.	E9	Health	Drug	Pharmaceutical Preparations	Farnum Rhonda	CA	O	SVP,COMM	3	S	-414	10.89	-38		370	D
7/16/25 16:30	7/14/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Tessari Eben	X0	O	COO	8	M.dm	4,385	20.89	210		72	D
7/16/25 16:30	7/14/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Tessari Eben	X0	O	COO	8	S.dm	-4,385	20.89	-210		72	D
7/16/25 16:20	7/14/25	ANNX	Annexon, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yednock Ted	CA	O	EVP,CHIE	1	S	-3	2.58	-1		105	D
7/16/25 16:20	7/14/25	ANNX	Annexon, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lew Jennifer	CA	O	EVP,CFO	1	S	-3	2.58	-1		122	D
7/16/25 16:20	7/14/25	ANNX	Annexon, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Overdorf Michael	CA	O	EVP,CHIE	1	S	-2	2.61	-1		131	D
7/16/25 16:14	7/15/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bredt David	MA	O	Chief Sc	3	S	-294	11.52	-26		452	D
7/15/25 21:29	7/14/25	CALC	Calcimedica, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Leheny A. Rachel	CA	DOT	CEO	1	P	6	2.47	3	0	874	I
7/15/25 20:54	7/11/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Monia Brett P	CA	DO	CEO	1	S	-48	41.74	-1		180	D
7/15/25 17:53	6/16/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Lewis William	NJ	DO	Chair,CE	13	S.dm	-21,380	56.14	-381		619	M
7/15/25 17:53	6/16/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Lewis William	NJ	DO	Chair,CE	13	M.dm	21,380	56.14	381	160	619	M
7/15/25 17:52	6/5/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Smith Michael Alexander	NJ	O	GC	5	S.m	-2,569	71.06	-36		92	D
7/15/25 17:38	7/14/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Blum Robert I	CA	DO	P,CEO	6	S	-1,043	34.77	-30		422	D
7/15/25 17:11	7/14/25	DYN	Dyne Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cox John	MA	DO	CEO,P	2	P	965	9.28	104	61	274	D
7/15/25 17:02	7/11/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Congleton Jon	PA	DO	CEO	1	S	-230	14.51	-16		846	D
7/15/25 17:01	7/11/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Levy Adam Scott	PA	O	CFO,Secr	1	S	-155	14.45	-11		207	D
7/15/25 17:00	7/14/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rodman David Malcom	PA	O	Chief Me	6	M.d	526	9.90	53	82	118	D
7/15/25 17:00	7/14/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rodman David Malcom	PA	O	Chief Me	6	S.d	-526	9.90	-53		118	D
7/15/25 16:36	7/11/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Schundler Russell	NC	O	GC	6	M.d	271	6.43	42	8	597	D
7/15/25 16:36	7/14/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Schundler Russell	NC	O	GC	6	S.d	-271	6.43	-42		597	D
7/15/25 16:36	7/11/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Saggar Rajeev	NC	O	Chief Me	5	M.d	238	6.52	37	15	273	D
7/15/25 16:36	7/14/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Saggar Rajeev	NC	O	Chief Me	5	S.d	-238	6.52	-37		273	D
7/15/25 16:35	7/11/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Moomaw Scott	NC	O	Chief Co	6	M.d	191	5.87	33	17	225	D
7/15/25 16:35	7/14/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Moomaw Scott	NC	O	Chief Co	6	S.d	-191	5.87	-33		225	D
7/15/25 16:35	7/14/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Krepp Sarah	NC	O	Chief Hu	1	S	-38	14.28	-3		142	D
7/15/25 16:34	7/11/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Kaseta Michael	NC	O	CFO,COO	6	M.d	431	6.67	65	19	412	D
7/15/25 16:34	7/14/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Kaseta Michael	NC	O	CFO,COO	6	S.d	-431	6.67	-65		412	D
7/15/25 16:33	7/11/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Jeffs Roger	NC	DO	CEO	6	M.d	1,098	6.54	168	7	2,633	D
7/15/25 16:33	7/14/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Jeffs Roger	NC	DO	CEO	6	S.d	-1,098	6.54	-168		2,633	D
7/15/25 16:30	7/14/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Boyle Dana	NC	O	Chief Ac	1	S	-17	14.28	-1		187	D
7/15/25 16:30	7/11/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Adair Jason	NC	O	Chief Bu	7	M.d	112	4.76	23	14	194	D
7/15/25 16:30	7/14/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Adair Jason	NC	O	Chief Bu	7	S.d	-112	4.76	-23		194	D
7/15/25 16:05	7/10/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Scadden David	MA	D		3	M.d	81	16.53	5	39	18	D
7/15/25 16:05	7/10/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Scadden David	MA	D		3	S.d	-81	16.53	-5		18	D
7/15/25 07:00	7/11/25	AVBP	Arrivent Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lachapelle Robin	PA	O	COO	1	M.d	25	2.28	11	2	530	D
7/15/25 06:03	7/11/25	ANIX	Anixa Biosciences Inc	DE	Health	Drug	Pharmaceutical Preparations	Titterton Lewis H Jr	CA	D		1	P	31	3.14	10	1	943	D
7/14/25 17:07	7/10/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hohl Benjamin	CO	O	CFO	10	M.d	306	11.12	28		23	D
7/14/25 17:07	7/10/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hohl Benjamin	CO	O	CFO	10	S.d	-306	11.12	-28		23	D
7/14/25 16:36	7/10/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Swisher Daniel N Jr	CA	D		6	M.d	560	42.40	13		0	D
7/14/25 16:36	7/10/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Swisher Daniel N Jr	CA	D		6	S.d	-560	42.40	-13	-100	0	D
7/14/25 16:30	7/10/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	12	M.d	28,037	212.40	132		37	D
7/14/25 16:30	7/10/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	12	S.d	-28,037	212.40	-132		37	D
7/14/25 16:30	7/10/25	COGT	Cogent Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fairmount Funds Management LLC	PA	D		2	P.dm	25,166	9.01	2,792	29	12,463	I
7/14/25 16:11	7/14/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Cook Meredith	MN	O	SVP,GC,S	3	S	-75	62.82	-1		80	D
7/14/25 16:02	5/8/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Burnett Patrick	CA	O	See Rema	4	S.dm	-525	8.20	-64		119	D
7/14/25 15:23	7/10/25	PRGO	Perrigo Co Plc	L2	Health	Drug	Pharmaceutical Preparations	Lockwood-Taylor Patrick	MI	DO	CEO	1	M.d	772	27.27	28	53	81	D
7/14/25 08:40	7/11/25	ANIX	Anixa Biosciences Inc	DE	Health	Drug	Pharmaceutical Preparations	Kumar Amit	CA	O	CEO	2	P	44	2.95	15	3	575	D
7/11/25 18:30	7/10/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cheng Andrew	CA	DO	P,CEO	4	S	-5,187	49.66	-104		594	D
7/11/25 18:17	7/10/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Kozarich John W	FL	D		2	S.d	-243	72.63	-3		46	D
7/11/25 17:50	6/2/25	CPIX	Cumberland Pharmaceuticals Inc		Health	Drug	Pharmaceutical Preparations	Young Caroline	TN	D		3	P.m	1	4.79	0	1	33	D
7/11/25 17:49	6/2/25	CPIX	Cumberland Pharmaceuticals Inc		Health	Drug	Pharmaceutical Preparations	Kazimi A J	TN	DOT	CB,CEO	3	P.m	2	4.79	1	0	5,699	D
7/11/25 17:48	6/2/25	CPIX	Cumberland Pharmaceuticals Inc		Health	Drug	Pharmaceutical Preparations	Jones James	TN	D		3	P.m	2	4.79	1	1	43	D
7/11/25 17:46	6/2/25	CPIX	Cumberland Pharmaceuticals Inc		Health	Drug	Pharmaceutical Preparations	Krogulski Kenneth	TN	D		3	P.m	14	4.79	3	1	287	D
7/11/25 17:27	7/9/25	TRDA	Entrada Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Parmar Kush	CA	DT		2	S.m	-1,069	7.03	-152		4,283	I
7/11/25 17:25	7/9/25	TRDA	Entrada Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5Am Ventures V, L.P.	CA	T		2	S.m	-1,069	7.03	-152		4,283	M
7/11/25 17:14	7/9/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Oyler John	V8	DO	CEO	5	S.dm	-12,552	3.06	-4,097		54,270	D
7/11/25 16:59	7/9/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gheuens Sarah	MA	O	Chief Me	6	M.d	988	21.86	45	281	61	D
7/11/25 16:59	7/9/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gheuens Sarah	MA	O	Chief Me	6	S.d	-988	21.86	-45		61	D
7/11/25 16:48	7/9/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Quisel John D	MA	DO	CEO	4	M.d	2,606	32.58	80	98	162	D
7/11/25 16:48	7/9/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Quisel John D	MA	DO	CEO	4	S.d	-2,606	32.58	-80		162	D
7/11/25 16:31	7/9/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Smith Hunter C	MA	O	CFO	5	M.d	5,326	38.58	138		117	D
7/11/25 16:31	7/9/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Smith Hunter C	MA	O	CFO	5	S.d	-5,326	38.58	-138		117	D
7/11/25 16:30	7/9/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Shulman Joseph	MA	O	Chief Te	2	M.d	674	42.29	16		9	D
7/11/25 16:30	7/9/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Shulman Joseph	MA	O	Chief Te	2	S.d	-674	42.29	-16		9	D
7/11/25 16:30	7/9/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	German Christopher Paul	MA	O	Corporat	4	M.d	544	55.51	10		2	D
7/11/25 16:30	7/9/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	German Christopher Paul	MA	O	Corporat	4	S.d	-544	55.51	-10		2	D
7/11/25 16:30	7/9/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pelish Henry E.	MA	O	Chief Sc	6	S.dm	-1,967	55.98	-35		63	D
7/11/25 16:30	7/10/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pelish Henry E.	MA	O	Chief Sc	6	M.dm	1,967	55.98	35	126	63	D
7/11/25 16:30	7/9/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cramer Pamela J.	MA	O	CHRO	6	M.d	2,442	41.20	59		19	D
7/11/25 16:30	7/9/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cramer Pamela J.	MA	O	CHRO	6	S.d	-2,442	41.20	-59		19	D
7/10/25 20:56	7/9/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Palleiko Benjamin L	MA	DO	CEO	7	S.d	-785	7.68	-102		370	D
7/10/25 20:56	7/8/25	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Nougues Maximo F	CA	O	CFO	1	S.m	-34	3.53	-10		204	D
7/10/25 20:52	7/8/25	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hunt Douglas M	CA	O	See Rema	1	S.m	-28	3.53	-8		165	D
7/10/25 20:50	7/9/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yea Christopher	MA	O	Chief De	7	S.d	-555	11.52	-48		128	D
7/10/25 20:49	7/8/25	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Auerbach Alan H	CA	DOT	P,CEO	1	S.m	-167	3.53	-47		7,181	D
7/10/25 17:15	7/10/25	OTLC	Oncotelic Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Trieu Vuong	CA	DOT	CB,CEO	1	P.m	1	0.0050	199	0	117,041	D
7/10/25 17:00	7/8/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Shelton Jerrell	TN	DO	P,CEO	8	M.dm	5,435	5.65	962	999%	962	D
7/10/25 16:45	7/8/25	LFCR	Lifecore Biomedical, Inc. De	DE	Health	Drug	Pharmaceutical Preparations	Salus Thomas D.	MN	O	Chief Le	1	M.d	0	0.00	37	18	241	D
7/10/25 16:42	7/8/25	LFCR	Lifecore Biomedical, Inc. De	DE	Health	Drug	Pharmaceutical Preparations	Lake Ryan David	MN	O	CFO	1	M.d	0	0.00	75	26	360	D
7/10/25 16:41	7/8/25	LFCR	Lifecore Biomedical, Inc. De	DE	Health	Drug	Pharmaceutical Preparations	Josephs Paul	MN	DO	CEO	1	M.d	0	0.00	150	31	633	D
7/10/25 16:30	7/9/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Silverstein Christine Berni	OH	D		1	S	-77	5.86	-13		120	D
7/10/25 16:30	7/9/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Seshadri Vishwas	OH	DO	CEO	2	S	-749	6.24	-120		1,304	D
7/10/25 16:30	7/9/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Vazzano Joseph Walter	OH	O	CFO	2	S	-269	6.23	-43		491	D
7/10/25 16:30	7/8/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Wuchterl Donald A.	OH	D		1	S	-30	5.82	-5		145	D
7/10/25 16:30	7/9/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Charles Faith L.	OH	D		1	S	-63	5.86	-11		139	D
7/10/25 16:30	7/9/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	O'Malley Brendan M.	OH	O	SVP,GC	2	S	-173	6.20	-28		378	D
7/10/25 16:30	7/9/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Alvino Mark	OH	D		3	S	-135	5.84	-23		92	D
7/10/25 16:17	7/8/25	ELTP	Elite Pharmaceuticals Inc /Nv/	NJ	Health	Drug	Pharmaceutical Preparations	Plassche Douglas	NJ	O	EVP Oper	2	S.d	-191	0.0707	-2,700		2,500	D
7/9/25 19:29	7/7/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Patel Anish	CO	O	COO	3	S	-390	19.50	-20		310	I
7/9/25 19:00	7/7/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rolph Timothy	CA	O	Chief Sc	10	M.dm	5,122	36.33	141	491	170	D
7/9/25 19:00	7/7/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rolph Timothy	CA	O	Chief Sc	10	S.dm	-5,122	36.33	-141		170	D
7/9/25 18:41	7/7/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Hahn Mark W	X0	O	CFO	7	M.dm	14,417	6.75	2,136	19	13,466	D
7/9/25 18:39	7/7/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Rickard Kathleen A.	X0	O	Chief Me	6	M.d	1,763	4.19	421	19	2,661	D
7/9/25 18:38	7/7/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Fisher Andrew	X0	O	GC	8	M.d	2,333	3.90	598		440	D
7/9/25 18:37	7/7/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Zaccardelli David	X0	DO	P,CEO	7	M.dm	14,418	6.75	2,136	17	14,377	D
7/9/25 17:00	7/7/25	MURA	Mural Oncology Plc	L2	Health	Drug	Pharmaceutical Preparations	Loew Caroline	L2	DO	CEO	1	S	-30	2.43	-13		293	D
7/9/25 16:34	7/8/25	ETST	Earth Science Tech, Inc.	FL	Health	Drug	Pharmaceutical Preparations	Sanchez Yovan Arturo	FL	D		2	P.m	18	0.1929	94	6	1,700	D
7/9/25 16:18	6/23/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Bonstein Sara	NJ	O	CFO	8	M.dm	20,383	61.95	329		113	D
7/9/25 16:18	6/23/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Bonstein Sara	NJ	O	CFO	8	S.dm	-20,383	61.95	-329		113	D
7/8/25 17:55	7/7/25	BRFG	Bullfrog Ai Holdings, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Singh Vininder	MD	DOT	CEO	2	S.m	-77	1.53	-50		2,321	D
7/8/25 16:37	7/7/25	ALXO	Alx Oncology Holdings Inc	DE	Health	Drug	Pharmaceutical Preparations	Pinto Shelly	CA	O	SVP,Fina	2	S	-2	0.4414	-4		89	D
7/8/25 16:21	7/8/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Malik Fady Ibraham	CA	O	EVP Rese	12	M.d	535	22.27	24	21	141	D
7/8/25 16:21	7/8/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Malik Fady Ibraham	CA	O	EVP Rese	12	S.d	-535	22.27	-24		141	D
7/8/25 16:20	7/3/25	BPMC	Blueprint Medicines Corp	DE	Health	Drug	Pharmaceutical Preparations	Rossi Christina	MA	O	COO	3	S	-610	106.69	-6		67	D
7/8/25 16:20	7/3/25	BPMC	Blueprint Medicines Corp	DE	Health	Drug	Pharmaceutical Preparations	Carter Percy H.	MA	O	Chief Sc	2	S	-475	127.98	-4		54	D
7/8/25 16:06	7/4/25	PRLD	Prelude Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Huang Jane	DE	O	P,CMO	1	M.d	0	0.00	9	13	81	D
7/8/25 16:05	7/3/25	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ondrey Aaron	NJ	O	CFO	1	S	-4	2.88	-1		128	D
7/8/25 16:00	7/3/25	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Schambye Hans T.	G7	DO	CEO	2	M.d	2	1.19	2	109	4	D
7/8/25 16:00	7/3/25	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Schambye Hans T.	G7	DO	CEO	2	S.d	-2	1.19	-2		4	D
7/8/25 16:00	7/3/25	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Winslow Garrett	G7	O	GC	2	M.d	1	0.9372	1	192	1	D
7/8/25 16:00	7/3/25	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Winslow Garrett	G7	O	GC	2	S.d	-1	0.9372	-1		1	D
7/8/25 16:00	7/3/25	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Firmani Lori	G7	O	Interim	2	M.d	0	0.9559	1	305	1	D
7/8/25 16:00	7/3/25	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Firmani Lori	G7	O	Interim	2	S.d	0	0.9559	-1		1	D
7/7/25 21:28	6/2/25	JUNS	Jupiter Neurosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Elmasri Saleem	FL	O	CFO,Secr	1	M.d	0	0.00	66		66	D
7/7/25 20:00	6/21/25	ERNA	Ernexa Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gurrola Sandra M	MA	O	SVP of F	1	M.d	0	0.00	0	38	0	D
7/7/25 17:20	7/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Lee Kevin	X0	DO	CEO	1	S.m	-40	7.29	-5		481	D
7/7/25 17:20	7/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Skynner Michael	X0	O	CTO	1	S.m	-13	7.28	-2		120	D
7/7/25 17:20	7/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Milnes Alistair	X0	O	COO	1	S.m	-15	7.25	-2		96	D
7/7/25 17:20	7/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Hannay Michael Charles Ferguson	X0	O	CHIEF PR	1	S.m	-5	7.21	-1		54	D
7/7/25 17:20	7/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Thompson Travis Alvin	X0	O	Chief Ac	1	S.m	-2	7.21	0		32	D
7/7/25 17:20	7/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Young Alethia	X0	O	CFO	1	S	-1	7.09	0	0	45	D
7/7/25 16:26	7/5/25	PGEN	Precigen, Inc.	VA	Health	Drug	Pharmaceutical Preparations	Agee Nancy H	MD	D		1	M.d	0	0.00	127	253	177	D
7/7/25 16:03	7/3/25	MLTX	Moonlake Immunotherapeutics	E9	Health	Drug	Pharmaceutical Preparations	Moukheibir Catherine	V8	D		2	M.d	1,147	24.40	47		0	D
7/7/25 16:03	7/3/25	MLTX	Moonlake Immunotherapeutics	E9	Health	Drug	Pharmaceutical Preparations	Moukheibir Catherine	V8	D		2	S.d	-1,147	24.40	-47	-100	0	D
7/7/25 08:59	7/2/25	IMRX	Immuneering Corp	DE	Health	Drug	Pharmaceutical Preparations	Hausman Diana	MA	D		1	P	20	3.61	6		6	M
7/7/25 08:52	7/2/25	IMRX	Immuneering Corp	DE	Health	Drug	Pharmaceutical Preparations	Neufeld Leah R	MA	O	CHIEF PE	1	P	2	3.57	1	7	11	D
7/3/25 20:56	7/1/25	JUNS	Jupiter Neurosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Silva Alison D.	FL	DO	P + Chie	3	P.m	3	0.0233	113		113	D
7/3/25 20:39	7/1/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Guyer William	CA	O	Chief De	8	M.d	5,660	47.63	119		5	D
7/3/25 20:39	7/1/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Guyer William	CA	O	Chief De	8	S.d	-5,660	47.63	-119		5	D
7/3/25 20:36	7/1/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Lyon Joseph Douglas	CA	O	See Rema	6	M.d	1,266	43.82	29		10	D
7/3/25 20:36	7/1/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Lyon Joseph Douglas	CA	O	See Rema	6	S.d	-1,266	43.82	-29		10	D
7/3/25 20:35	7/1/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Maduck Sean	CA	O	See Rema	6	M.dm	4,678	42.83	109	999%	117	D
7/3/25 20:35	7/1/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Maduck Sean	CA	O	See Rema	6	S.dm	-4,678	42.83	-109		117	D
7/3/25 19:51	7/1/25	PMVP	Pmv Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ticktin Robert	NJ	O	GC,COO	1	S	-25	1.06	-23		99	D
7/3/25 19:50	7/1/25	PMVP	Pmv Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jalota Deepika	NJ	O	Chief De	1	S	-35	1.06	-33		90	D
7/3/25 19:49	7/1/25	PMVP	Pmv Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Carulli Michael	NJ	O	CFO	1	S	-30	1.06	-28		60	D
7/3/25 19:48	7/1/25	PMVP	Pmv Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mack David Henry	NJ	DO	P,CEO	1	S	-62	1.06	-58		906	D
7/3/25 19:39	7/1/25	LFVN	Lifevantage Corp		Health	Drug	Pharmaceutical Preparations	Aure Carl	UT	O	CFO	2	M.d	37	7.14	5	4	133	D
7/3/25 19:39	7/1/25	LFVN	Lifevantage Corp		Health	Drug	Pharmaceutical Preparations	Aure Carl	UT	O	CFO	2	S.d	-37	7.14	-5		133	D
7/3/25 19:39	7/1/25	LFVN	Lifevantage Corp		Health	Drug	Pharmaceutical Preparations	Neufeld Alissa	UT	O	GC	1	M.d	0	0.00	3	3	92	D
7/3/25 19:39	7/1/25	LFVN	Lifevantage Corp		Health	Drug	Pharmaceutical Preparations	Cunningham Kristen	UT	O	Chief Sa	1	M.d	0	0.00	3	3	104	D
7/3/25 19:38	7/1/25	LFVN	Lifevantage Corp		Health	Drug	Pharmaceutical Preparations	Boyster Julie	UT	O	CMO	1	M.d	0	0.00	4	3	115	D
7/3/25 18:48	7/1/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Howe Jolanda	CA	O	SVP,GLOB	2	M.dm	51	24.32	2	605	2	D
7/3/25 18:48	7/2/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Howe Jolanda	CA	O	SVP,GLOB	2	S.dm	-51	24.32	-2		2	D
7/3/25 18:00	7/1/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lamy Patrick	CA	O	SVP,Comm	11	S.d	-1,508	37.90	-40		33	D
7/3/25 17:30	7/2/25	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Petersen Floyd F.	CA	D		3	S.d	-37	24.41	-2		78	D
7/3/25 17:12	7/1/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Garfield Alastair	MA	O	Chief Sc	2	M.d	85	14.83	6		3	D
7/3/25 17:12	7/2/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Garfield Alastair	MA	O	Chief Sc	2	S.d	-85	14.83	-6		3	D
7/3/25 16:39	7/1/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Levy Richard S	X0	D		2	M.d	0	0.00	4	30	18	D
7/3/25 16:30	7/1/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kumar Neil	CA	DO	CEO	4	S.dm	-9,345	29.13	-321		6,081	I

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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