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10/30/03 20:10
7/17/03
ESPRHealthDrugPharmaceutical PreparationsDurus Life Sciences Master Fund LtdTP.m3,59519.46018529,370D
10/30/03 19:58
7/8/03
ESPRHealthDrugPharmaceutical PreparationsDurus Life Sciences Master Fund LtdTP.m4,13719.95020729,588D
10/30/03 19:55
6/27/03
ESPRHealthDrugPharmaceutical PreparationsDurus Life Sciences Master Fund LtdTP.m2,41419.060127110,214D
10/30/03 19:51
6/17/03
ESPRHealthDrugPharmaceutical PreparationsDurus Life Sciences Master Fund LtdTP.m21,20716.4101,2931311,175D
10/30/03 19:47
6/6/03
ESPRHealthDrugPharmaceutical PreparationsDurus Life Sciences Master Fund LtdTP.m7,45115.610477510,046D
10/30/03 19:40
5/20/03
ESPRHealthDrugPharmaceutical PreparationsDurus Life Sciences Master Fund LtdTP.m9,02113.03069279,962D
10/30/03 19:37
5/8/03
ESPRHealthDrugPharmaceutical PreparationsDurus Life Sciences Master Fund LtdTP.m6,46111.83054669,302D
10/30/03 19:33
4/25/03
ESPRHealthDrugPharmaceutical PreparationsDurus Life Sciences Master Fund LtdTP.m3,47311.62029948,822D
10/30/03 19:31
4/1/03
ESPRHealthDrugPharmaceutical PreparationsDurus Life Sciences Master Fund LtdTP.m9,1879.870931128,703D
10/30/03 19:20
2/26/03
ESPRHealthDrugPharmaceutical PreparationsDurus Life Sciences Master Fund LtdTP.m8,0708.760921137,814D
10/30/03 18:21
1/27/03
ESPRHealthDrugPharmaceutical PreparationsDurus Life Sciences Master Fund LtdTP.m3,1806.74047276,893D
10/30/03 18:20
10/14/02
ESPRHealthDrugPharmaceutical PreparationsDurus Life Sciences Master Fund LtdTP.m2,3745.40044095,214D
10/30/03 18:17
12/27/02
ESPRHealthDrugPharmaceutical PreparationsDurus Life Sciences Master Fund LtdTP.m4,0006.860583106,422D
10/30/03 18:14
12/9/02
ESPRHealthDrugPharmaceutical PreparationsDurus Life Sciences Master Fund LtdTP.m1,8506.55028255,838D
10/30/03 18:12
11/20/02
ESPRHealthDrugPharmaceutical PreparationsDurus Life Sciences Master Fund LtdTP.m1,1966.56018235,556D
10/30/03 18:10
10/30/02
ESPRHealthDrugPharmaceutical PreparationsDurus Life Sciences Master Fund LtdTP.m9666.05016035,374D
10/30/03 18:05
9/25/02
ESPRHealthDrugPharmaceutical PreparationsDurus Life Sciences Master Fund LtdTP.m1,4535.53026364,788D
10/30/03 17:56
9/12/02
ESPRHealthDrugPharmaceutical PreparationsDurus Life Sciences Master Fund LtdTP.m2,3795.760413104,536D
10/30/03 17:49
8/30/02
ESPRHealthDrugPharmaceutical PreparationsDurus Life Sciences Master Fund LtdTP.m2,7875.610497144,144D
10/30/03 17:44
8/9/02
ESPRHealthDrugPharmaceutical PreparationsDurus Life Sciences Master Fund LtdTP.m7755.42014343,658D
10/30/03 17:41
7/23/02
ESPRHealthDrugPharmaceutical PreparationsDurus Life Sciences Master Fund LtdTP.m7194.62015626,984D
10/30/03 17:38
7/5/02
ESPRHealthDrugPharmaceutical PreparationsDurus Life Sciences Master Fund LtdTP.m8034.98016153,359D
10/30/03 17:34
6/18/02
ESPRHealthDrugPharmaceutical PreparationsDurus Life Sciences Master Fund LtdTP.m1,2714.93025846,213D
7/31/03 18:30
7/17/03
ESPRHealthDrugPharmaceutical PreparationsDurus Capital ManagementCTTP.m3,59819.48018529,727I
7/31/03 18:29
7/8/03
ESPRHealthDrugPharmaceutical PreparationsDurus Capital ManagementCTTP.m4,14019.960207210,089I
7/31/03 18:29
6/26/03
ESPRHealthDrugPharmaceutical PreparationsDurus Capital ManagementCTTP.m10,88318.300595610,621I
7/31/03 18:28
6/17/03
ESPRHealthDrugPharmaceutical PreparationsDurus Capital ManagementCTTP.m14,38415.570924911,079I
7/31/03 18:27
6/5/03
ESPRHealthDrugPharmaceutical PreparationsDurus Capital ManagementCTTP.m6,24315.440404410,304I
7/31/03 18:26
5/22/03
ESPRHealthDrugPharmaceutical PreparationsDurus Capital ManagementCTTP.m8,84513.110675710,292I
7/31/03 18:26
5/12/03
ESPRHealthDrugPharmaceutical PreparationsDurus Capital ManagementCTTP.m8,41311.86070989,651I
7/31/03 18:25
4/30/03
ESPRHealthDrugPharmaceutical PreparationsDurus Capital ManagementCTTP.m4,69211.84039658,983I
7/31/03 18:25
4/4/03
ESPRHealthDrugPharmaceutical PreparationsDurus Capital ManagementCTTP.m7,12010.16070198,771I
7/31/03 18:24
3/4/03
ESPRHealthDrugPharmaceutical PreparationsDurus Capital ManagementCTTP.m10,6329.1701,159197,263I
7/31/03 18:22
1/31/03
ESPRHealthDrugPharmaceutical PreparationsDurus Capital ManagementCTTP.m3,0896.790455313,526I
7/31/03 18:22
1/2/03
ESPRHealthDrugPharmaceutical PreparationsDurus Capital ManagementCTTP.m4,0146.880584512,542I
7/31/03 18:21
12/11/02
ESPRHealthDrugPharmaceutical PreparationsDurus Capital ManagementCTTP.m2,2976.75034065,935I
7/31/03 18:21
11/22/02
ESPRHealthDrugPharmaceutical PreparationsDurus Capital ManagementCTTP.m1,2506.51019245,594I
7/31/03 18:20
11/1/02
ESPRHealthDrugPharmaceutical PreparationsDurus Capital ManagementCTTP.m9726.23015635,402I
7/31/03 18:20
10/16/02
ESPRHealthDrugPharmaceutical PreparationsDurus Capital ManagementCTTP.m1,9945.50036275,246I
7/31/03 18:20
9/30/02
ESPRHealthDrugPharmaceutical PreparationsDurus Capital ManagementCTTP.m1,7645.42032674,885I
7/31/03 18:19
9/16/02
ESPRHealthDrugPharmaceutical PreparationsDurus Capital ManagementCTTP.m2,3235.790401104,582I
7/31/03 18:19
9/3/02
ESPRHealthDrugPharmaceutical PreparationsDurus Capital ManagementCTTP.m2,8265.630502144,201I
7/31/03 18:18
8/16/02
ESPRHealthDrugPharmaceutical PreparationsDurus Capital ManagementCTTP.m1,0115.65017937,297I
7/31/03 18:18
7/25/02
ESPRHealthDrugPharmaceutical PreparationsDurus Capital ManagementCTTP.m5584.60012143,531I
7/31/03 18:17
7/10/02
ESPRHealthDrugPharmaceutical PreparationsDurus Capital ManagementCTTP.m9114.91018563,410I
7/31/03 18:16
6/21/02
ESPRHealthDrugPharmaceutical PreparationsDurus Capital ManagementCTTP.m1,2594.99025283,225I
7/31/03 18:16
5/29/02
ESPRHealthDrugPharmaceutical PreparationsDurus Capital ManagementCTTP.m1,6604.62035975,736I

DDerivative transaction in filing (usually option exercise)
MMultiple transactions in filing; earliest reported transaction date and weighted average transaction price
AAmended filing
EError detected in filing
S - SaleSale of securities on an exchange or to another person
S - Sale+OESale of securities on an exchange or to another person (after option exercise)
F - TaxPayment of exercise price or tax liability using portion of securities received from the company
P - PurchasePurchase of securities on an exchange or from another person
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