12/5/25 20:51 | 12/3/25 | STOK | Stoke Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Ticho Barry | MA | O | Chief Me | M.d | 0 | 0.00 | 0 | 10 | 102 | 20 | D | | | | | | | | | | | | | | |
12/5/25 20:51 | 12/4/25 | STOK | Stoke Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Ticho Barry | MA | O | Chief Me | S.dm | -167 | 31.19 | 0 | -5 | -21 | 20 | D | | | | | | | | | | | | | | |
12/5/25 20:50 | 12/3/25 | STOK | Stoke Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kaye Edward M. Md | MA | D | | M.d | 0 | 0.00 | 0 | 26 | 72 | 63 | D | | | | | | | | | | | | | | |
12/5/25 20:50 | 12/4/25 | STOK | Stoke Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kaye Edward M. Md | MA | D | | S.dm | -467 | 31.13 | 0 | -15 | -19 | 63 | D | | | | | | | | | | | | | | |
12/5/25 20:49 | 12/3/25 | STOK | Stoke Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Allan Jonathan | MA | O | GC,Corp | M.d | 0 | 0.00 | 0 | 6 | 61 | 16 | D | | | | | | | | | | | | | | |
12/5/25 20:49 | 12/4/25 | STOK | Stoke Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Allan Jonathan | MA | O | GC,Corp | S.dm | -306 | 31.25 | 0 | -10 | -38 | 16 | D | | | | | | | | | | | | | | |
12/5/25 20:00 | 12/4/25 | DNTH | Dianthus Therapeutics, Inc. /De/ | DE | Health | Drug | Pharmaceutical Preparations | Savitz Ryan | NY | O | CFO,CBO | M.d | 169 | 8.44 | 0 | 20 | | 0 | D | | | | | | | | | | | | | | |
12/5/25 20:00 | 12/4/25 | DNTH | Dianthus Therapeutics, Inc. /De/ | DE | Health | Drug | Pharmaceutical Preparations | Savitz Ryan | NY | O | CFO,CBO | S.d | -904 | 45.18 | 0 | -20 | -100 | 0 | D | | | | | | | | | | | | | | |
12/5/25 18:53 | 12/5/25 | ENTA | Enanta Pharmaceuticals Inc | | Health | Drug | Pharmaceutical Preparations | Capps Kathleen S. | MA | O | See Rema | S | -5 | 14.23 | 0 | 0 | -4 | 8 | D | | | | | | | | | | | | | | |
12/5/25 18:47 | 12/5/25 | ENTA | Enanta Pharmaceuticals Inc | | Health | Drug | Pharmaceutical Preparations | Trout Harry R. III | MA | O | See Rema | S | -8 | 14.23 | 0 | -1 | -3 | 16 | D | | | | | | | | | | | | | | |
12/5/25 18:46 | 12/5/25 | ENTA | Enanta Pharmaceuticals Inc | | Health | Drug | Pharmaceutical Preparations | Rottinghaus Scott T. | MA | O | Chief Me | S | -11 | 14.23 | 0 | -1 | -4 | 22 | D | | | | | | | | | | | | | | |
12/5/25 18:45 | 12/5/25 | ENTA | Enanta Pharmaceuticals Inc | | Health | Drug | Pharmaceutical Preparations | Luu Brendan | MA | O | Chief Bu | S | -20 | 14.23 | 0 | -1 | -4 | 38 | D | | | | | | | | | | | | | | |
12/5/25 18:44 | 12/5/25 | ENTA | Enanta Pharmaceuticals Inc | | Health | Drug | Pharmaceutical Preparations | Kieffer Tara Lynn | MA | O | Chief Pr | S | -30 | 14.23 | 0 | -2 | -6 | 31 | D | | | | | | | | | | | | | | |
12/5/25 18:43 | 12/5/25 | ENTA | Enanta Pharmaceuticals Inc | | Health | Drug | Pharmaceutical Preparations | Or Yat Sun | MA | O | Chief Sc | S | -34 | 14.23 | 0 | -2 | -1 | 371 | D | | | | | | | | | | | | | | |
12/5/25 18:41 | 12/5/25 | ENTA | Enanta Pharmaceuticals Inc | | Health | Drug | Pharmaceutical Preparations | Luly Jay R. | MA | DO | P,CEO | S | -67 | 14.23 | 0 | -5 | -1 | 858 | D | | | | | | | | | | | | | | |
12/5/25 18:20 | 12/4/25 | BIOA | Bioage Labs, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Rubin Paul D | CA | O | Chief Me | M.d | 283 | 4.11 | 0 | 69 | | 0 | D | | | | | | | | | | | | | | |
12/5/25 18:20 | 12/4/25 | BIOA | Bioage Labs, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Rubin Paul D | CA | O | Chief Me | S.d | -702 | 10.19 | 0 | -69 | -100 | 0 | D | | | | | | | | | | | | | | |
12/5/25 18:02 | 12/3/25 | TBPH | Theravance Biopharma, Inc. | CA | Health | Drug | Pharmaceutical Preparations | Farnum Rhonda | CA | O | SVP,COMM | S | -583 | 18.75 | 0 | -31 | -10 | 278 | D | | | | | | | | | | | | | | |
12/5/25 17:47 | 12/4/25 | ORIC | Oric Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kunkel Lori Anne | CA | D | | M.d | 21 | 3.75 | 0 | 6 | 8 | 74 | D | | | | | | | | | | | | | | |
12/5/25 17:46 | 12/2/25 | TENX | Tenax Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Rich Stuart | NC | DO | Chief Me | P.dm | 46 | 9.12 | 0 | 5 | 188 | 8 | M | | | | | | | | | | | | | | |
12/5/25 17:35 | 12/5/25 | CYTK | Cytokinetics Inc | | Health | Drug | Pharmaceutical Preparations | Callos Andrew | CA | O | EVP,Chie | M.d | 1,776 | 33.84 | 0 | 52 | | 51 | D | | | | | | | | | | | | | | |
12/5/25 17:35 | 12/5/25 | CYTK | Cytokinetics Inc | | Health | Drug | Pharmaceutical Preparations | Callos Andrew | CA | O | EVP,Chie | S.d | -3,461 | 65.95 | 0 | -52 | -51 | 51 | D | | | | | | | | | | | | | | |
12/5/25 17:01 | 12/3/25 | RPRX | Royalty Pharma Plc | X0 | Health | Drug | Pharmaceutical Preparations | Lloyd George W. | NY | O | EVP,Inve | S | -4,375 | 39.77 | 0 | -110 | -11 | 890 | I | | | | | | | | | | | | | | |
12/5/25 16:54 | 12/3/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Rothblatt Martine A | MD | DO | CHAIRPER | M.dm | 962 | 120.26 | 0 | 8 | 1 | 644 | D | | | | | | | | | | | | | | |
12/5/25 16:54 | 12/3/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Rothblatt Martine A | MD | DO | CHAIRPER | S.dm | -3,821 | 477.64 | 0 | -8 | -1 | 644 | D | | | | | | | | | | | | | | |
12/5/25 16:21 | 12/3/25 | ALKS | Alkermes Plc. | | Health | Drug | Pharmaceutical Preparations | Hopkinson Craig C. | MA | O | EVP R,D, | M.d | 72 | 19.34 | 0 | 4 | 6 | 66 | D | | | | | | | | | | | | | | |
12/5/25 16:21 | 12/3/25 | ALKS | Alkermes Plc. | | Health | Drug | Pharmaceutical Preparations | Hopkinson Craig C. | MA | O | EVP R,D, | S.d | -112 | 30.00 | 0 | -4 | -5 | 66 | D | | | | | | | | | | | | | | |
12/5/25 16:16 | 12/3/25 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Wagner Charles F Jr | MA | O | EVP,CO,F | S | -6,384 | 456.00 | 0 | -14 | -27 | 38 | D | | | | | | | | | | | | | | |
12/5/25 16:15 | 12/4/25 | RCUS | Arcus Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Jaen Juan C. | CA | O | P | S | -2,051 | 24.71 | 0 | -83 | -6 | 1,321 | I | | | | | | | | | | | | | | |
12/5/25 16:12 | 12/3/25 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Tatsis Ourania | MA | O | EVP,Chie | S | -2,025 | 449.99 | 0 | -5 | -9 | 47 | D | | | | | | | | | | | | | | |
12/5/25 16:11 | 12/5/25 | DYN | Dyne Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Cox John | MA | DO | CEO,P | S | -55 | 20.72 | 0 | -3 | -1 | 269 | D | | | | | | | | | | | | | | |
12/5/25 16:11 | 12/4/25 | INSM | Insmed Inc | VA | Health | Drug | Pharmaceutical Preparations | Lewis William | NJ | DO | Chair,CE | M.d | 267 | 24.94 | 0 | 11 | 2 | 588 | D | | | | | | | | | | | | | | |
12/5/25 16:11 | 12/4/25 | INSM | Insmed Inc | VA | Health | Drug | Pharmaceutical Preparations | Lewis William | NJ | DO | Chair,CE | S.d | -2,200 | 205.62 | 0 | -11 | -2 | 588 | D | | | | | | | | | | | | | | |
12/5/25 16:10 | 12/3/25 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Leiden Jeffrey M | MA | DO | Exec CB | M.dm | 5,518 | 86.52 | 0 | 64 | | 24 | D | | | | | | | | | | | | | | |
12/5/25 16:10 | 12/3/25 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Leiden Jeffrey M | MA | DO | Exec CB | S.d | -28,650 | 449.20 | 0 | -64 | -72 | 24 | D | | | | | | | | | | | | | | |
12/5/25 16:09 | 12/5/25 | DYN | Dyne Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kerr Douglas | MA | O | Chief Me | S | -18 | 20.72 | 0 | -1 | -1 | 88 | D | | | | | | | | | | | | | | |
12/5/25 16:08 | 12/5/25 | DYN | Dyne Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Friedl-Naderer Johanna | MA | O | Chief Co | S | -3 | 20.72 | 0 | 0 | 0 | 95 | D | | | | | | | | | | | | | | |
12/5/25 16:06 | 12/3/25 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Biller Jonathan | MA | O | EVP,GC | S | -156 | 449.00 | 0 | 0 | -2 | 15 | D | | | | | | | | | | | | | | |
12/4/25 21:30 | 12/2/25 | CRMD | Cormedix Inc. | DE | Health | Drug | Pharmaceutical Preparations | Dillione Janet | NJ | D | | M.d | 185 | 3.96 | 0 | 47 | 999% | 48 | D | | | | | | | | | | | | | | |
12/4/25 21:30 | 12/2/25 | CRMD | Cormedix Inc. | DE | Health | Drug | Pharmaceutical Preparations | Dillione Janet | NJ | D | | S.d | -467 | 10.00 | 0 | -47 | -49 | 48 | D | | | | | | | | | | | | | | |
12/4/25 20:11 | 12/2/25 | ALMS | Alumis Inc. | DE | Health | Drug | Pharmaceutical Preparations | Akkaraju Srinivas | CA | D | | P.m | 2,040 | 7.79 | 0 | 262 | 5 | 5,571 | I | | | | | | | | | | | | | | |
12/4/25 19:56 | 12/2/25 | SER | Serina Therapeutics, Inc. | AL | Health | Drug | Pharmaceutical Preparations | Moreadith Randall | AL | O | Chief Sc | M.dm | 0 | 0.0600 | 0 | 7 | | 0 | D | | | | | | | | | | | | | | |
12/4/25 19:56 | 12/2/25 | SER | Serina Therapeutics, Inc. | AL | Health | Drug | Pharmaceutical Preparations | Moreadith Randall | AL | O | Chief Sc | S.dm | -23 | 3.61 | 0 | -7 | -100 | 0 | D | | | | | | | | | | | | | | |
12/4/25 19:39 | 12/2/25 | AXSM | Axsome Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Tabuteau Herriot | NY | DOT | CEO | M.dm | 641 | 8.02 | 0 | 80 | 1 | 7,352 | D | | | | | | | | | | | | | | |
12/4/25 19:39 | 12/2/25 | AXSM | Axsome Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Tabuteau Herriot | NY | DOT | CEO | S.dm | -11,649 | 145.66 | 0 | -80 | -1 | 7,352 | D | | | | | | | | | | | | | | |
12/4/25 19:32 | 12/2/25 | MNKD | Mannkind Corp | DE | Health | Drug | Pharmaceutical Preparations | Castagna Michael | CT | DO | CEO | M.d | 491 | 4.55 | 0 | 108 | 5 | 2,505 | D | | | | | | | | | | | | | | |
12/4/25 19:32 | 12/2/25 | MNKD | Mannkind Corp | DE | Health | Drug | Pharmaceutical Preparations | Castagna Michael | CT | DO | CEO | S.d | -601 | 5.57 | 0 | -108 | -4 | 2,505 | D | | | | | | | | | | | | | | |
12/4/25 19:27 | 12/2/25 | MNKD | Mannkind Corp | DE | Health | Drug | Pharmaceutical Preparations | Thomson David | CT | O | EVP Genl | M.d | 677 | 4.58 | 0 | 148 | 21 | 842 | D | | | | | | | | | | | | | | |
12/4/25 19:27 | 12/2/25 | MNKD | Mannkind Corp | DE | Health | Drug | Pharmaceutical Preparations | Thomson David | CT | O | EVP Genl | S.d | -823 | 5.57 | 0 | -148 | -15 | 842 | D | | | | | | | | | | | | | | |
12/4/25 19:00 | 12/2/25 | QTTB | Q32 Bio Inc. | DE | Health | Drug | Pharmaceutical Preparations | Morrison Jodie Pope | MA | DO | CEO | S | -78 | 3.46 | 0 | -23 | -19 | 99 | D | | | | | | | | | | | | | | |
12/4/25 19:00 | 12/2/25 | QTTB | Q32 Bio Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kalowski Lee | MA | O | CFO,P | S | -31 | 3.46 | 0 | -9 | -19 | 40 | D | | | | | | | | | | | | | | |
12/4/25 18:55 | 12/2/25 | SVRA | Savara Inc | DE | Health | Drug | Pharmaceutical Preparations | Elam Nevan C | PA | D | | M.d | 9 | 1.46 | 0 | 6 | 10 | 67 | D | | | | | | | | | | | | | | |
12/4/25 18:34 | 12/3/25 | PAHC | Phibro Animal Health Corp | DE | Health | Drug | Pharmaceutical Preparations | Bendheim Jack | NJ | DOT | P,CEO | S.dm | -289 | 41.00 | 0 | -7 | -10 | 67 | I | | | | | | | | | | | | | | |
12/4/25 18:20 | 12/2/25 | HOWL | Werewolf Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Evnin Luke | MA | D | | S.m | -118 | 0.9176 | 0 | -128 | -4 | 3,068 | I | | | | | | | | | | | | | | |
12/4/25 18:19 | 12/2/25 | HOWL | Werewolf Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Mpm Bioventures 2014, L.P. | MA | H | Former 1 | S.m | -183 | 0.9176 | 0 | -200 | -4 | 4,784 | I | | | | | | | | | | | | | | |
12/4/25 18:18 | 12/2/25 | HOWL | Werewolf Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Gadicke Ansbert | MA | H | Former 1 | S.m | -183 | 0.9176 | 0 | -200 | -4 | 4,784 | I | | | | | | | | | | | | | | |
12/4/25 17:26 | 12/3/25 | MDGL | Madrigal Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Sibold William John | PA | DO | P,CEO | M.d | 0 | 0.00 | 0 | 50 | 50 | 150 | D | | | | | | | | | | | | | | |
12/4/25 17:26 | 12/4/25 | MDGL | Madrigal Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Sibold William John | PA | DO | P,CEO | S.d | -1,381 | 575.34 | 0 | -2 | -2 | 150 | D | | | | | | | | | | | | | | |
12/4/25 17:15 | 12/2/25 | SONN | Sonnet Biotherapeutics Holdings, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kenney Richard T | NJ | O | Chief Me | M.d | 0 | 0.00 | 0 | 250 | | 0 | D | | | | | | | | | | | | | | |
12/4/25 16:57 | 12/2/25 | GALT | Galectin Therapeutics Inc | NV | Health | Drug | Pharmaceutical Preparations | 10X Fund, L.P. | GA | T | | S.m | -852 | 5.68 | 0 | -150 | -3 | 5,682 | D | | | | | | | | | | | | | | |
12/4/25 16:54 | 12/2/25 | VSTM | Verastem, Inc. | MA | Health | Drug | Pharmaceutical Preparations | Paterson Dan | MA | DO | P,CEO | S.m | -61 | 10.11 | 0 | -6 | -1 | 421 | D | | | | | | | | | | | | | | |
12/4/25 16:50 | 12/2/25 | ACRS | Aclaris Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Davis Hugh M. | PA | DO | P,COO | M.d | 0 | 0.00 | 0 | 27 | New | 27 | D | | | | | | | | | | | | | | |
12/4/25 16:15 | 12/2/25 | BMEA | Biomea Fusion, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Hitchcock Michael J.M. | CA | DO | Interim | P | 99 | 0.9918 | 0 | 100 | 667 | 115 | D | | | | | | | | | | | | | | |
12/4/25 16:05 | 12/3/25 | VERA | Vera Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Turner William D. | CA | O | Chief Re | M.d | 155 | 15.53 | 0 | 10 | 80 | 23 | D | | | | | | | | | | | | | | |
12/4/25 16:05 | 12/3/25 | VERA | Vera Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Turner William D. | CA | O | Chief Re | S.d | -400 | 40.00 | 0 | -10 | -31 | 23 | D | | | | | | | | | | | | | | |
12/4/25 16:02 | 11/21/25 | KALV | Kalvista Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Sweeny Nicole | MA | O | Chief Co | M.dm | 0 | 0.00 | 0 | 11 | 40 | 40 | D | | | | | | | | | | | | | | |
12/4/25 16:02 | 11/24/25 | KALV | Kalvista Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Sweeny Nicole | MA | O | Chief Co | S.d | -51 | 13.45 | 0 | -4 | -9 | 40 | D | | | | | | | | | | | | | | |
12/4/25 16:01 | 12/2/25 | TEVA | Teva Pharmaceutical Industries Ltd | L3 | Health | Drug | Pharmaceutical Preparations | Lichtenstein Chen | L3 | D | | M.d | 0 | 0.00 | 0 | 5 | New | 5 | D | | | | | | | | | | | | | | |
12/4/25 07:31 | 11/25/25 | MAIA | Maia Biotechnology, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Vitoc Vlad | IL | DOT | CEO | P.a | 10 | 0.9661 | 0 | 11 | 1 | 1,042 | D | | | | | | | | | | | | | | |
12/4/25 07:30 | 11/26/25 | MAIA | Maia Biotechnology, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Vitoc Vlad | IL | DOT | CEO | P.am | 80 | 1.11 | 0 | 72 | 7 | 1,114 | D | | | | | | | | | | | | | | |
12/3/25 21:52 | 12/1/25 | SYRE | Spyre Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Turtle Cameron | MA | DO | CEO | S | -435 | 29.02 | 0 | -15 | -2 | 687 | D | | | | | | | | | | | | | | |
12/3/25 21:19 | 12/2/25 | CORT | Corcept Therapeutics Inc | DE | Health | Drug | Pharmaceutical Preparations | Guyer William | CA | O | Chief De | M.d | 433 | 21.65 | 0 | 20 | | 1 | M | | | | | | | | | | | | | | |
12/3/25 21:19 | 12/2/25 | CORT | Corcept Therapeutics Inc | DE | Health | Drug | Pharmaceutical Preparations | Guyer William | CA | O | Chief De | S.d | -1,602 | 80.08 | 0 | -20 | -94 | 1 | M | | | | | | | | | | | | | | |
12/3/25 20:53 | 12/1/25 | CORT | Corcept Therapeutics Inc | DE | Health | Drug | Pharmaceutical Preparations | Maduck Sean | CA | O | See Rema | M.d | 165 | 8.27 | 0 | 20 | 20 | 118 | D | | | | | | | | | | | | | | |
12/3/25 20:53 | 12/1/25 | CORT | Corcept Therapeutics Inc | DE | Health | Drug | Pharmaceutical Preparations | Maduck Sean | CA | O | See Rema | S.d | -1,590 | 79.52 | 0 | -20 | -15 | 118 | D | | | | | | | | | | | | | | |
12/3/25 20:36 | 12/1/25 | CORT | Corcept Therapeutics Inc | DE | Health | Drug | Pharmaceutical Preparations | Lyon Joseph Douglas | CA | O | See Rema | M.d | 68 | 13.56 | 0 | 5 | 91 | 11 | D | | | | | | | | | | | | | | |
12/3/25 20:36 | 12/1/25 | CORT | Corcept Therapeutics Inc | DE | Health | Drug | Pharmaceutical Preparations | Lyon Joseph Douglas | CA | O | See Rema | S.d | -398 | 79.53 | 0 | -5 | -32 | 11 | D | | | | | | | | | | | | | | |
12/3/25 20:23 | 12/1/25 | STOK | Stoke Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Ticho Barry | MA | O | Chief Me | M.d | 0 | 0.00 | 0 | 12 | 377 | 15 | D | | | | | | | | | | | | | | |
12/3/25 20:23 | 12/2/25 | STOK | Stoke Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Ticho Barry | MA | O | Chief Me | S.dm | -121 | 30.22 | 0 | -4 | -21 | 15 | D | | | | | | | | | | | | | | |
12/3/25 20:22 | 12/1/24 | STOK | Stoke Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kaye Edward M. Md | MA | D | | M.d | 0 | 0.00 | 0 | 4 | 9 | 51 | D | | | | | | | | | | | | | | |
12/3/25 20:22 | 12/2/25 | STOK | Stoke Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kaye Edward M. Md | MA | D | | S.dm | -65 | 30.22 | 0 | -2 | -4 | 51 | D | | | | | | | | | | | | | | |
12/3/25 20:20 | 11/28/25 | XENE | Xenon Pharmaceuticals Inc. | A1 | Health | Drug | Pharmaceutical Preparations | Mortimer Ian | A1 | DO | P,CEO | S | -4 | 45.01 | 0 | 0 | 0 | 46 | D | | | | | | | | | | | | | | |
12/3/25 20:20 | 12/1/25 | STOK | Stoke Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Allan Jonathan | MA | O | GC,Corp | M.d | 0 | 0.00 | 0 | 12 | 170 | 20 | D | | | | | | | | | | | | | | |
12/3/25 20:20 | 12/2/25 | STOK | Stoke Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Allan Jonathan | MA | O | GC,Corp | S.dm | -138 | 30.22 | 0 | -5 | -19 | 20 | D | | | | | | | | | | | | | | |
12/3/25 20:14 | 12/1/25 | CORT | Corcept Therapeutics Inc | DE | Health | Drug | Pharmaceutical Preparations | Belanoff Joseph K | CA | DO | CEO | S | -3,191 | 79.77 | 0 | -40 | -1 | 2,701 | I | | | | | | | | | | | | | | |
12/3/25 20:11 | 12/1/25 | FOLD | Amicus Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Campbell Bradley L | NJ | DO | P,CEO | M.d | 132 | 9.03 | 0 | 15 | 1 | 1,137 | D | | | | | | | | | | | | | | |
12/3/25 20:11 | 12/1/25 | FOLD | Amicus Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Campbell Bradley L | NJ | DO | P,CEO | S.d | -146 | 10.01 | 0 | -15 | -1 | 1,137 | D | | | | | | | | | | | | | | |
12/3/25 20:08 | 11/25/25 | CORT | Corcept Therapeutics Inc | DE | Health | Drug | Pharmaceutical Preparations | Guyer William | CA | O | Chief De | S.a | -364 | 80.90 | 0 | -5 | -85 | 1 | M | | | | | | | | | | | | | | |
12/3/25 20:00 | 12/1/25 | JANX | Janux Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Meyer Andrew Hollman | CA | O | Chief Bu | M.d | 35 | 10.59 | 0 | 3 | 4 | 85 | D | | | | | | | | | | | | | | |
12/3/25 20:00 | 12/1/25 | JANX | Janux Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Meyer Andrew Hollman | CA | O | Chief Bu | S.d | -110 | 32.98 | 0 | -3 | -4 | 85 | D | | | | | | | | | | | | | | |
12/3/25 19:01 | 12/1/25 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Wender Joseph H | CA | D | | S | -2,263 | 80.82 | 0 | -28 | -35 | 52 | I | | | | | | | | | | | | | | |
12/3/25 17:59 | 12/2/25 | MDGL | Madrigal Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Dier Mardi | PA | O | EVP,CFO | M.d | 1,050 | 251.63 | 0 | 4 | 67 | 10 | D | | | | | | | | | | | | | | |
12/3/25 17:59 | 12/2/25 | MDGL | Madrigal Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Dier Mardi | PA | O | EVP,CFO | S.d | -2,413 | 578.34 | 0 | -4 | -29 | 10 | D | | | | | | | | | | | | | | |
12/3/25 17:39 | 12/1/25 | SLGL | Sol-Gel Technologies Ltd. | L3 | Health | Drug | Pharmaceutical Preparations | Opaleye Management Inc. | MA | T | | P.m | 258 | 37.53 | 0 | 7 | 2 | 381 | I | | | | | | | | | | | | | | |
12/3/25 17:24 | 12/1/25 | ARQT | Arcutis Biotherapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Matsuda Masaru | CA | O | See Rema | S | -50 | 30.23 | 0 | -2 | -1 | 151 | D | | | | | | | | | | | | | | |
12/3/25 17:23 | 12/1/25 | ARQT | Arcutis Biotherapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Welgus Howard G. | CA | D | | S | -302 | 30.21 | 0 | -10 | -11 | 80 | D | | | | | | | | | | | | | | |
12/3/25 17:11 | 12/1/25 | RPRX | Royalty Pharma Plc | X0 | Health | Drug | Pharmaceutical Preparations | Coyne Terrance P. | NY | O | EVP,CFO | S | -2,774 | 39.87 | 0 | -70 | -9 | 690 | I | | | | | | | | | | | | | | |
12/3/25 17:10 | 12/1/25 | RPRX | Royalty Pharma Plc | X0 | Health | Drug | Pharmaceutical Preparations | Urist Marshall | NY | O | EVP,Rese | S | -1,659 | 39.92 | 0 | -42 | -15 | 228 | M | | | | | | | | | | | | | | |
12/3/25 17:09 | 12/2/25 | ENTA | Enanta Pharmaceuticals Inc | | Health | Drug | Pharmaceutical Preparations | Capps Kathleen S. | MA | O | See Rema | S | -3 | 13.96 | 0 | 0 | -2 | 9 | D | | | | | | | | | | | | | | |
12/3/25 17:08 | 12/1/25 | LGND | Ligand Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Kozarich John W | FL | D | | S | -91 | 195.84 | 0 | 0 | -1 | 44 | D | | | | | | | | | | | | | | |
12/3/25 17:05 | 12/2/25 | ENTA | Enanta Pharmaceuticals Inc | | Health | Drug | Pharmaceutical Preparations | Trout Harry R. III | MA | O | See Rema | S | -5 | 13.96 | 0 | 0 | -2 | 17 | D | | | | | | | | | | | | | | |
12/3/25 17:02 | 12/1/25 | NUVB | Nuvation Bio Inc. | DE | Health | Drug | Pharmaceutical Preparations | Liu Dongfang | NY | O | CHIEF ME | M.d | 440 | 2.93 | 0 | 150 | | 18 | D | | | | | | | | | | | | | | |
12/3/25 17:02 | 12/1/25 | NUVB | Nuvation Bio Inc. | DE | Health | Drug | Pharmaceutical Preparations | Liu Dongfang | NY | O | CHIEF ME | S.d | -1,173 | 7.82 | 0 | -150 | -89 | 18 | D | | | | | | | | | | | | | | |
12/3/25 16:39 | 12/1/25 | AMLX | Amylyx Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Bedrosian Camille L | MA | O | Chief Me | S | -94 | 14.35 | 0 | -7 | -4 | 176 | D | | | | | | | | | | | | | | |
12/3/25 16:30 | 12/1/25 | ANNX | Annexon, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Choi Jung | CA | D | | P | 138 | 4.19 | 0 | 33 | New | 33 | I | | | | | | | | | | | | | | |
12/3/25 16:30 | 12/1/25 | ANNX | Annexon, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Carson William H. | CA | D | | P | 18 | 4.47 | 0 | 4 | 9 | 50 | D | | | | | | | | | | | | | | |
12/3/25 16:30 | 12/1/25 | TVTX | Travere Therapeutics, Inc. | CA | Health | Drug | Pharmaceutical Preparations | Cline Christopher R. | CA | O | CFO | M.d | 325 | 16.23 | 0 | 20 | 28 | 92 | D | | | | | | | | | | | | | | |
12/3/25 16:30 | 12/1/25 | TVTX | Travere Therapeutics, Inc. | CA | Health | Drug | Pharmaceutical Preparations | Cline Christopher R. | CA | O | CFO | S.d | -700 | 35.01 | 0 | -20 | -18 | 92 | D | | | | | | | | | | | | | | |
12/3/25 16:28 | 12/1/25 | CRNX | Crinetics Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Pizzuti Dana | CA | O | Chief Me | M.d | 84 | 16.89 | 0 | 5 | 8 | 67 | D | | | | | | | | | | | | | | |
12/3/25 16:28 | 12/1/25 | CRNX | Crinetics Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Pizzuti Dana | CA | O | Chief Me | S.d | -225 | 45.02 | 0 | -5 | -7 | 67 | D | | | | | | | | | | | | | | |
12/3/25 16:16 | 12/2/25 | TRVI | Trevi Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Galletta Christopher | CT | O | See Rema | M.d | 2 | 0.5110 | 0 | 4 | 19 | 26 | D | | | | | | | | | | | | | | |
12/3/25 16:01 | 12/1/25 | INSM | Insmed Inc | VA | Health | Drug | Pharmaceutical Preparations | Flammer Martina M.D. | NJ | O | Chief Me | M.d | 230 | 25.83 | 0 | 9 | 12 | 83 | D | | | | | | | | | | | | | | |
12/3/25 16:01 | 12/1/25 | INSM | Insmed Inc | VA | Health | Drug | Pharmaceutical Preparations | Flammer Martina M.D. | NJ | O | Chief Me | S.d | -1,841 | 206.98 | 0 | -9 | -10 | 83 | D | | | | | | | | | | | | | | |
12/2/25 19:00 | 12/1/25 | GNLX | Genelux Corp | DE | Health | Drug | Pharmaceutical Preparations | Thomas John | CA | D | | S | -50 | 5.00 | 0 | -10 | -2 | 493 | D | | | | | | | | | | | | | | |
12/2/25 18:45 | 11/28/25 | PHAT | Phathom Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Basta Steven L | | DO | P,CEO | M.d | 0 | 0.00 | 0 | 90 | | 83 | D | | | | | | | | | | | | | | |
12/2/25 17:14 | 12/1/25 | XERS | Xeris Biopharma Holdings, Inc. | | Health | Drug | Pharmaceutical Preparations | Hecht Beth | IL | O | See Rema | S | -117 | 7.01 | 0 | -17 | -1 | 1,320 | D | | | | | | | | | | | | | | |
12/2/25 17:14 | 12/2/25 | CYTK | Cytokinetics Inc | | Health | Drug | Pharmaceutical Preparations | Henderson John T | CA | D | | M.d | 88 | 10.00 | 0 | 9 | 13 | 75 | D | | | | | | | | | | | | | | |
12/2/25 17:14 | 12/2/25 | CYTK | Cytokinetics Inc | | Health | Drug | Pharmaceutical Preparations | Henderson John T | CA | D | | S.d | -559 | 63.90 | 0 | -9 | -10 | 75 | D | | | | | | | | | | | | | | |
12/2/25 17:10 | 12/2/25 | CYTK | Cytokinetics Inc | | Health | Drug | Pharmaceutical Preparations | Malik Fady Ibraham | CA | O | EVP Rese | M.d | 23 | 10.60 | 0 | 2 | 2 | 141 | D | | | | | | | | | | | | | | |
12/2/25 17:10 | 12/2/25 | CYTK | Cytokinetics Inc | | Health | Drug | Pharmaceutical Preparations | Malik Fady Ibraham | CA | O | EVP Rese | S.d | -141 | 63.89 | 0 | -2 | -2 | 141 | D | | | | | | | | | | | | | | |
12/2/25 16:43 | 11/28/25 | PBH | Prestige Consumer Healthcare Inc. | | Health | Drug | Pharmaceutical Preparations | Zerillo Jeffrey | NY | O | SVP Oper | S.m | -60 | 60.00 | 0 | -1 | -2 | 42 | D | | | | | | | | | | | | | | |
12/2/25 16:34 | 11/28/25 | LQDA | Liquidia Corp | DE | Health | Drug | Pharmaceutical Preparations | Schundler Russell | NC | O | GC | M.d | 0 | 0.00 | 0 | 2 | 0 | 592 | D | | | | | | | | | | | | | | |
12/2/25 16:34 | 12/1/25 | LQDA | Liquidia Corp | DE | Health | Drug | Pharmaceutical Preparations | Schundler Russell | NC | O | GC | S.d | -35 | 32.19 | 0 | -1 | 0 | 592 | D | | | | | | | | | | | | | | |
12/2/25 16:33 | 12/1/25 | LQDA | Liquidia Corp | DE | Health | Drug | Pharmaceutical Preparations | Krepp Sarah | NC | O | Chief Hu | S | -7 | 32.19 | 0 | 0 | 0 | 141 | D | | | | | | | | | | | | | | |
12/2/25 16:32 | 12/1/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Edgemond James | MD | O | CFO,TREA | M.d | 3,067 | 146.03 | 0 | 21 | | 8 | D | | | | | | | | | | | | | | |
12/2/25 16:32 | 12/1/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Edgemond James | MD | O | CFO,TREA | S.d | -10,080 | 479.99 | 0 | -21 | -72 | 8 | D | | | | | | | | | | | | | | |
12/2/25 16:32 | 11/28/25 | LQDA | Liquidia Corp | DE | Health | Drug | Pharmaceutical Preparations | Kaseta Michael | NC | O | CFO,COO | M.d | 0 | 0.00 | 0 | 2 | 1 | 354 | D | | | | | | | | | | | | | | |
12/2/25 16:32 | 12/1/25 | LQDA | Liquidia Corp | DE | Health | Drug | Pharmaceutical Preparations | Kaseta Michael | NC | O | CFO,COO | S.d | -38 | 32.19 | 0 | -1 | 0 | 354 | D | | | | | | | | | | | | | | |
12/2/25 16:32 | 12/1/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Rothblatt Martine A | MD | DO | CHAIRPER | M.dm | 962 | 120.26 | 0 | 8 | 1 | 644 | D | | | | | | | | | | | | | | |
12/2/25 16:32 | 12/1/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Rothblatt Martine A | MD | DO | CHAIRPER | S.dm | -3,853 | 481.61 | 0 | -8 | -1 | 644 | D | | | | | | | | | | | | | | |
12/2/25 16:31 | 12/1/25 | LQDA | Liquidia Corp | DE | Health | Drug | Pharmaceutical Preparations | Boyle Dana | NC | O | Chief Ac | S | -10 | 32.19 | 0 | 0 | 0 | 155 | D | | | | | | | | | | | | | | |
12/2/25 16:31 | 12/1/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Benkowitz Michael | MD | O | P,COO | M.d | 2,872 | 127.66 | 0 | 23 | | 3 | I | | | | | | | | | | | | | | |
12/2/25 16:31 | 12/1/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Benkowitz Michael | MD | O | P,COO | S.d | -10,798 | 479.92 | 0 | -23 | -89 | 3 | I | | | | | | | | | | | | | | |
12/2/25 16:31 | 11/28/25 | LQDA | Liquidia Corp | DE | Health | Drug | Pharmaceutical Preparations | Adair Jason | NC | O | Chief Bu | M.d | 0 | 0.00 | 0 | 2 | 1 | 176 | D | | | | | | | | | | | | | | |
12/2/25 16:31 | 12/1/25 | LQDA | Liquidia Corp | DE | Health | Drug | Pharmaceutical Preparations | Adair Jason | NC | O | Chief Bu | S.d | -22 | 32.19 | 0 | -1 | 0 | 176 | D | | | | | | | | | | | | | | |
12/2/25 16:30 | 11/28/25 | NUVL | Nuvalent, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Noci Darlene | MA | O | Chief De | M.d | 111 | 27.85 | 0 | 4 | 9 | 48 | D | | | | | | | | | | | | | | |
12/2/25 16:30 | 11/28/25 | NUVL | Nuvalent, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Noci Darlene | MA | O | Chief De | S.d | -434 | 108.58 | 0 | -4 | -8 | 48 | D | | | | | | | | | | | | | | |
12/2/25 16:30 | 11/28/25 | LQDA | Liquidia Corp | DE | Health | Drug | Pharmaceutical Preparations | Moomaw Scott | NC | O | Chief Co | M.d | 0 | 0.00 | 0 | 2 | 1 | 155 | D | | | | | | | | | | | | | | |
12/2/25 16:30 | 12/1/25 | LQDA | Liquidia Corp | DE | Health | Drug | Pharmaceutical Preparations | Moomaw Scott | NC | O | Chief Co | S.d | -27 | 32.19 | 0 | -1 | -1 | 155 | D | | | | | | | | | | | | | | |
12/2/25 16:15 | 11/28/25 | PAHC | Phibro Animal Health Corp | DE | Health | Drug | Pharmaceutical Preparations | Bendheim Jack | NJ | DOT | P,CEO | S.m | -296 | 42.10 | 0 | -7 | -14 | 44 | I | | | | | | | | | | | | | | |
12/2/25 16:15 | 11/28/25 | BMEA | Biomea Fusion, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Erdtmann Rainer M | CA | DO | See Rema | P.m | 55 | 1.09 | 0 | 50 | 2 | 2,543 | D | | | | | | | | | | | | | | |
12/2/25 16:04 | 12/1/25 | MIRM | Mirum Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Grey Michael G | CA | D | | M.d | 147 | 2.94 | 0 | 50 | 22 | 280 | D | | | | | | | | | | | | | | |
12/2/25 16:04 | 12/1/25 | MIRM | Mirum Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Grey Michael G | CA | D | | S.d | -3,700 | 74.00 | 0 | -50 | -15 | 280 | D | | | | | | | | | | | | | | |
12/2/25 16:02 | 11/28/25 | RNAC | Cartesian Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | English Emily | MD | O | Chief Op | M.d | 25 | 3.30 | 0 | 8 | 14 | 63 | D | | | | | | | | | | | | | | |
12/2/25 09:18 | 12/1/25 | CYTK | Cytokinetics Inc | | Health | Drug | Pharmaceutical Preparations | Kaye Edward M. Md | CA | D | | M.d | 385 | 13.72 | 0 | 28 | | 10 | D | | | | | | | | | | | | | | |
12/2/25 09:18 | 12/1/25 | CYTK | Cytokinetics Inc | | Health | Drug | Pharmaceutical Preparations | Kaye Edward M. Md | CA | D | | S.d | -1,872 | 66.72 | 0 | -28 | -74 | 10 | D | | | | | | | | | | | | | | |
12/2/25 09:13 | 12/1/25 | CYTK | Cytokinetics Inc | | Health | Drug | Pharmaceutical Preparations | Harrington Robert Arthur | CA | D | | S | -144 | 66.80 | 0 | -2 | -10 | 19 | D | | | | | | | | | | | | | | |
12/1/25 19:02 | 11/26/25 | TBPH | Theravance Biopharma, Inc. | CA | Health | Drug | Pharmaceutical Preparations | Broshy Eran | CA | D | | S.d | -590 | 20.00 | 0 | -30 | -40 | 45 | D | | | | | | | | | | | | | | |
12/1/25 18:14 | 11/26/25 | JAZZ | Jazz Pharmaceuticals Plc | L2 | Health | Drug | Pharmaceutical Preparations | Cozadd Bruce C | L2 | D | | M.d | 9,560 | 123.36 | 0 | 78 | 25 | 393 | D | | | | | | | | | | | | | | |
12/1/25 18:14 | 11/26/25 | JAZZ | Jazz Pharmaceuticals Plc | L2 | Health | Drug | Pharmaceutical Preparations | Cozadd Bruce C | L2 | D | | S.d | -13,780 | 177.81 | 0 | -78 | -16 | 393 | D | | | | | | | | | | | | | | |
12/1/25 18:13 | 11/26/25 | HOWL | Werewolf Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Evnin Luke | MA | D | | S.m | -88 | 0.9643 | 0 | -91 | -3 | 3,196 | I | | | | | | | | | | | | | | |
12/1/25 18:12 | 11/26/25 | HOWL | Werewolf Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Mpm Bioventures 2014, L.P. | MA | T | | S.m | -137 | 0.9643 | 0 | -142 | -3 | 4,984 | I | | | | | | | | | | | | | | |
12/1/25 18:11 | 11/26/25 | HOWL | Werewolf Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Gadicke Ansbert | MA | T | | S.m | -137 | 0.9643 | 0 | -142 | -3 | 4,984 | I | | | | | | | | | | | | | | |
12/1/25 18:10 | 11/28/25 | ARWR | Arrowhead Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Ferrari Mauro | CA | D | | S | -493 | 56.39 | 0 | -9 | -11 | 69 | D | | | | | | | | | | | | | | |
12/1/25 18:09 | 11/26/25 | RCUS | Arcus Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Azoy Alexander | CA | O | Chief Ac | M.d | 25 | 13.33 | 0 | 2 | 7 | 27 | D | | | | | | | | | | | | | | |
12/1/25 18:09 | 11/26/25 | RCUS | Arcus Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Azoy Alexander | CA | O | Chief Ac | S.d | -49 | 26.00 | 0 | -2 | -6 | 27 | D | | | | | | | | | | | | | | |
12/1/25 18:09 | 11/26/25 | ALMS | Alumis Inc. | DE | Health | Drug | Pharmaceutical Preparations | Akkaraju Srinivas | CA | D | | P.m | 1,311 | 7.55 | 0 | 174 | 3 | 5,309 | I | | | | | | | | | | | | | | |
12/1/25 17:41 | 12/1/25 | ALKS | Alkermes Plc. | | Health | Drug | Pharmaceutical Preparations | Hopkinson Craig C. | MA | O | EVP R,D, | S | -117 | 29.30 | 0 | -4 | -6 | 66 | D | | | | | | | | | | | | | | |
12/1/25 17:17 | 11/26/25 | URGN | Urogen Pharma Ltd. | L3 | Health | Drug | Pharmaceutical Preparations | Holden Stuart | NJ | D | | M.d | 0 | 0.00 | 0 | 2 | New | 2 | D | | | | | | | | | | | | | | |
12/1/25 16:57 | 11/26/25 | ONC | Beone Medicines Ltd. | | Health | Drug | Pharmaceutical Preparations | Sanders Corazon (Corsee) D. | V8 | D | | M.d | 418 | 159.03 | 0 | 3 | 5 | 57 | D | | | | | | | | | | | | | | |
12/1/25 16:57 | 11/26/25 | ONC | Beone Medicines Ltd. | | Health | Drug | Pharmaceutical Preparations | Sanders Corazon (Corsee) D. | V8 | D | | S.d | -896 | 340.90 | 0 | -3 | -4 | 57 | D | | | | | | | | | | | | | | |
12/1/25 16:52 | 11/26/25 | URGN | Urogen Pharma Ltd. | L3 | Health | Drug | Pharmaceutical Preparations | Butitta Cynthia M | NJ | D | | M.d | 0 | 0.00 | 0 | 2 | New | 2 | D | | | | | | | | | | | | | | |
12/1/25 16:47 | 11/26/25 | URGN | Urogen Pharma Ltd. | L3 | Health | Drug | Pharmaceutical Preparations | Robinson James A. Jr. | NJ | D | | M.d | 0 | 0.00 | 0 | 2 | New | 2 | D | | | | | | | | | | | | | | |
12/1/25 16:46 | 11/26/25 | URGN | Urogen Pharma Ltd. | L3 | Health | Drug | Pharmaceutical Preparations | Wen Leana | NJ | D | | M.d | 0 | 0.00 | 0 | 2 | New | 2 | D | | | | | | | | | | | | | | |
12/1/25 16:44 | 11/26/25 | URGN | Urogen Pharma Ltd. | L3 | Health | Drug | Pharmaceutical Preparations | Wildman Daniel George | NJ | D | | M.d | 0 | 0.00 | 0 | 2 | New | 2 | D | | | | | | | | | | | | | | |
12/1/25 16:40 | 11/26/25 | VSTM | Verastem, Inc. | MA | Health | Drug | Pharmaceutical Preparations | Paterson Dan | MA | DO | P,CEO | S.m | -63 | 10.50 | 0 | -6 | -1 | 427 | D | | | | | | | | | | | | | | |
12/1/25 16:37 | 11/26/25 | KNSA | Kiniksa Pharmaceuticals International, Plc | | Health | Drug | Pharmaceutical Preparations | Tessari Eben | X0 | O | COO | M.d | 5 | 22.89 | 0 | 0 | 1 | 23 | D | | | | | | | | | | | | | | |
12/1/25 16:37 | 11/26/25 | KNSA | Kiniksa Pharmaceuticals International, Plc | | Health | Drug | Pharmaceutical Preparations | Tessari Eben | X0 | O | COO | S.d | -9 | 42.89 | 0 | 0 | -1 | 23 | D | | | | | | | | | | | | | | |
12/1/25 16:31 | 11/26/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Rothblatt Martine A | MD | DO | CHAIRPER | M.dm | 962 | 120.26 | 0 | 8 | 1 | 644 | D | | | | | | | | | | | | | | |
12/1/25 16:31 | 11/26/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Rothblatt Martine A | MD | DO | CHAIRPER | S.dm | -3,891 | 486.34 | 0 | -8 | -1 | 644 | D | | | | | | | | | | | | | | |
12/1/25 16:17 | 11/26/25 | RAPP | Rapport Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Gault Cheryl | MA | O | COO | M.d | 9 | 1.80 | 0 | 5 | 3 | 172 | D | | | | | | | | | | | | | | |
12/1/25 16:17 | 11/26/25 | RAPP | Rapport Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Gault Cheryl | MA | O | COO | S.d | -150 | 30.10 | 0 | -5 | -3 | 172 | D | | | | | | | | | | | | | | |
12/1/25 16:15 | 11/26/25 | JNJ | Johnson & Johnson | NJ | Health | Drug | Pharmaceutical Preparations | Morikis John G | NJ | D | | P | 258 | 206.15 | 0 | 1 | 209 | 2 | D | | | | | | | | | | | | | | |
12/1/25 16:10 | 11/26/25 | ALNY | Alnylam Pharmaceuticals, Inc. | | Health | Drug | Pharmaceutical Preparations | Greenstreet Yvonne | MA | DO | CEO | M.d | 500 | 106.40 | 0 | 5 | 7 | 69 | D | | | | | | | | | | | | | | |
12/1/25 16:07 | 11/26/25 | CVRX | Cvrx, Inc. | NJ | Health | Drug | Pharmaceutical Preparations | Johnson & Johnson | NJ | T | | S | -64 | 10.03 | 0 | -6 | 0 | 4,041 | I | | | | | | | | | | | | | | |
12/1/25 16:02 | 11/26/25 | TEVA | Teva Pharmaceutical Industries Ltd | L3 | Health | Drug | Pharmaceutical Preparations | Mignone Roberto | L3 | D | | S | -1,302 | 26.03 | 0 | -50 | -8 | 550 | I | | | | | | | | | | | | | | |
12/1/25 09:07 | 11/28/25 | KTTA | Pasithea Therapeutics Corp. | DE | Health | Drug | Pharmaceutical Preparations | Steinman Lawrence | FL | D | | P | 100 | 0.7500 | 0 | 133 | 201 | 200 | D | | | | | | | | | | | | | | |
12/1/25 08:56 | 11/28/25 | KTTA | Pasithea Therapeutics Corp. | DE | Health | Drug | Pharmaceutical Preparations | Marques Tiago | FL | DO | CEO | P | 25 | 0.7500 | 0 | 33 | 83 | 73 | D | | | | | | | | | | | | | | |
12/1/25 08:54 | 11/28/25 | KTTA | Pasithea Therapeutics Corp. | DE | Health | Drug | Pharmaceutical Preparations | Dumesnil Simon | FL | D | | P | 25 | 0.7500 | 0 | 33 | 999% | 36 | D | | | | | | | | | | | | | | |
12/1/25 06:20 | 11/28/25 | MAIA | Maia Biotechnology, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Vitoc Vlad | IL | DOT | CEO | P.m | 80 | 1.11 | 0 | 72 | 7 | 1,063 | D | | | | | | | | | | | | | | |
12/1/25 06:18 | 11/26/25 | MAIA | Maia Biotechnology, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Luput Cristian | IL | D | | P.m | 42 | 1.10 | 0 | 38 | 10 | 438 | D | | | | | | | | | | | | | | |
12/1/25 06:14 | 11/26/25 | MAIA | Maia Biotechnology, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Smith Stan | IL | D | | P | 16 | 1.04 | 0 | 15 | 1 | 1,364 | I | | | | | | | | | | | | | | |
11/28/25 17:51 | 11/25/25 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Klein Joseph III | CA | D | | M.d | 0 | 0.00 | 0 | 12 | 270 | 16 | I | | | | | | | | | | | | | | |
11/28/25 17:51 | 11/25/25 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Klein Joseph III | CA | D | | S.d | -960 | 80.00 | 0 | -12 | -42 | 16 | I | | | | | | | | | | | | | | |
11/28/25 17:51 | 11/25/25 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Devers Shannon L. | CA | O | EVP,Chie | M.d | 902 | 53.77 | 0 | 17 | 999% | 17 | D | | | | | | | | | | | | | | |
11/28/25 17:51 | 11/25/25 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Devers Shannon L. | CA | O | EVP,Chie | S.d | -1,357 | 80.91 | 0 | -17 | -49 | 17 | D | | | | | | | | | | | | | | |
11/28/25 17:38 | 11/25/25 | BHC | Bausch Health Companies Inc. | NJ | Health | Drug | Pharmaceutical Preparations | Paulson & Co. Inc. | NJ | T | | P | 15,625 | 6.25 | 0 | 2,500 | 4 | 73,256 | I | | | | | | | | | | | | | | |
11/28/25 17:00 | 11/26/25 | CPRX | Catalyst Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Del Carmen Jeffrey | FL | O | Chief Co | M.d | 46 | 4.21 | 0 | 11 | | 4 | D | | | | | | | | | | | | | | |
11/28/25 17:00 | 11/26/25 | CPRX | Catalyst Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Del Carmen Jeffrey | FL | O | Chief Co | S.d | -256 | 23.33 | 0 | -11 | -73 | 4 | D | | | | | | | | | | | | | | |
11/28/25 16:05 | 11/25/25 | MRUS | Merus N.V. | P7 | Health | Drug | Pharmaceutical Preparations | Shuman Harry | P7 | O | VP Contr | M.d | 0 | 0.00 | 0 | 8 | 307 | 11 | D | | | | | | | | | | | | | | |
11/28/25 16:05 | 11/25/25 | MRUS | Merus N.V. | P7 | Health | Drug | Pharmaceutical Preparations | Shuman Harry | P7 | O | VP Contr | S.d | -796 | 95.92 | 0 | -8 | -43 | 11 | D | | | | | | | | | | | | | | |
11/28/25 09:00 | 11/26/25 | COCP | Cocrystal Pharma, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Frost Phillip Md Et Al | FL | DT | | P | 4 | 0.9938 | 0 | 4 | 0 | 1,731 | I | | | | | | | | | | | | | | |
11/28/25 06:52 | 11/25/25 | MAIA | Maia Biotechnology, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Luput Cristian | IL | D | | P | 10 | 0.9785 | 0 | 10 | 3 | 399 | D | | | | | | | | | | | | | | |
11/28/25 06:48 | 11/25/25 | MAIA | Maia Biotechnology, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Vitoc Vlad | IL | DOT | CEO | P | 10 | 0.9661 | 0 | 11 | 1 | 1,041 | D | | | | | | | | | | | | | | |
11/28/25 06:05 | 11/25/25 | GLSI | Greenwich Lifesciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Patel Snehal | TX | DOT | CEO,CFO | P | 39 | 8.37 | 0 | 5 | 0 | 5,588 | D | | | | | | | | | | | | | | |
11/28/25 06:03 | 11/25/25 | AKRO | Akero Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Rolph Timothy | CA | O | Chief Sc | M.d | 624 | 4.09 | 0 | 153 | 118 | 282 | D | | | | | | | | | | | | | | |
11/26/25 21:30 | 11/24/25 | CRMD | Cormedix Inc. | DE | Health | Drug | Pharmaceutical Preparations | Dillione Janet | NJ | D | | M.d | 96 | 3.64 | 0 | 26 | 119 | 48 | D | | | | | | | | | | | | | | |
11/26/25 21:30 | 11/24/25 | CRMD | Cormedix Inc. | DE | Health | Drug | Pharmaceutical Preparations | Dillione Janet | NJ | D | | S.d | -262 | 9.93 | 0 | -26 | -35 | 48 | D | | | | | | | | | | | | | | |
11/26/25 21:18 | 11/24/25 | FOLD | Amicus Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Castelli Jeff | NJ | O | Chief De | M.d | 452 | 9.03 | 0 | 50 | 13 | 439 | D | | | | | | | | | | | | | | |
11/26/25 21:18 | 11/24/25 | FOLD | Amicus Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Castelli Jeff | NJ | O | Chief De | S.d | -774 | 10.16 | 0 | -76 | -15 | 439 | D | | | | | | | | | | | | | | |