Pharmaceutical Preparations Industry - Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	Title	T	TVal	Price	Qty	oc	Own	H
9/17/25 20:08	9/15/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chopas James George	MA	O	VP,Chief	S	-5	24.19	0	0	53	D
9/17/25 19:39	9/16/25	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	Tross Stuart A	CT	O	Chief Pe	S	-251	5.34	-47	-4	1,032	D
9/17/25 19:00	9/16/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jacobson Mark L.	NY	O	COO	S.d	-5,241	114.48	-46	-100	0	D
9/17/25 19:00	9/16/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jacobson Mark L.	NY	O	COO	M.d	197	4.91	40		0	D
9/17/25 18:58	9/17/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gregory Julia P	CA	D		M.d	20	1.86	11	New	11	D
9/17/25 18:06	9/16/25	TNGX	Tango Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Third Rock Ventures Iv, L.P.	MA	T		S	-2,559	7.04	-364	-2	14,364	D
9/17/25 17:22	9/15/25	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	Topper James N	CA	D		P	16	23.70	1	0	6,830	I
9/17/25 17:20	9/17/25	IMMX	Immix Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rachman Ilya M	CA	DO	CEO,CB	P	5	2.02	3	0	1,141	D
9/17/25 17:20	9/16/25	IMMX	Immix Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Morris Gabriel S	CA	DO	CFO	P	5	1.97	3	0	586	D
9/17/25 17:01	9/15/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Meisner Lara	MA	O	GC	M.d	86	5.45	16		0	D
9/17/25 17:01	9/15/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Meisner Lara	MA	O	GC	S.d	-182	11.49	-16	-100	0	D
9/17/25 16:45	9/15/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Tessari Eben	X0	O	COO	M.d	57	8.83	7	23	35	D
9/17/25 16:45	9/15/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Tessari Eben	X0	O	COO	S.d	-598	36.46	-16	-32	35	D
9/17/25 16:31	9/15/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Porter James Richard	MA	DO	P,CEO	M.d	511	18.93	27	12	249	D
9/17/25 16:31	9/15/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Porter James Richard	MA	DO	P,CEO	S.d	-2,135	79.08	-27	-10	249	D
9/17/25 16:30	9/16/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	M.d	481	120.26	4	1	644	D
9/17/25 16:30	9/16/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	S.d	-1,601	400.27	-4	-1	644	D
9/17/25 16:30	9/15/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Singh Raman	NC	D		M.d	116	2.55	46		31	D
9/17/25 16:30	9/15/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Singh Raman	NC	D		S.d	-1,175	25.81	-46	-59	31	D
9/17/25 16:15	9/15/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bredt David	MA	O	Chief Sc	S	-206	24.19	-9	-2	418	D
9/17/25 16:03	9/15/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McCarthy Teresa	CA	O	CHRO	M.d	335	22.34	15	18	97	D
9/17/25 16:03	9/15/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McCarthy Teresa	CA	O	CHRO	S.d	-621	41.41	-15	-13	97	D
9/17/25 16:02	9/15/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Orwin John A	CA	D		M.d	0	0.00	1	14	11	D
9/17/25 16:02	9/15/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hughes Steven George	CA	O	Chief Me	M.d	10	6.57	2	4	39	D
9/17/25 16:02	9/15/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hughes Steven George	CA	O	Chief Me	S.d	-70	45.41	-2	-4	39	D
9/17/25 09:45	9/15/25	CALC	Calcimedica, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Roberts Eric W	CA	DOT	CHIEF BU	P	9	2.68	3	0	1,061	I
9/17/25 06:02	9/15/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Benkowitz Michael	MD	O	P,COO	M.d	3,131	139.13	23		3	I
9/17/25 06:02	9/15/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Benkowitz Michael	MD	O	P,COO	S.d	-9,013	400.56	-23	-89	3	I
9/16/25 21:45	9/12/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dunton Alan W	NJ	D		M.d	36	3.55	10	33	40	D
9/16/25 21:45	9/12/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dunton Alan W	NJ	D		S.d	-131	13.13	-10	-20	40	D
9/16/25 21:21	9/10/25	BFRI	Biofrontera Inc.	DE	Health	Drug	Pharmaceutical Preparations	Luebbert Hermann	MA	DO	CEO,CB	M.d	0	0.00	138	904	153	D
9/16/25 21:19	9/10/25	BFRI	Biofrontera Inc.	DE	Health	Drug	Pharmaceutical Preparations	Leffler Eugene Frederick	MA	O	CFO	M.d	0	0.00	88	New	88	D
9/16/25 19:45	9/12/25	BYSI	Beyondspring Inc.		Health	Drug	Pharmaceutical Preparations	Decheng Capital China Life Sciences Usd Fund Iii, L.P.	CA	T		S.m	-8	1.85	-4	0	4,380	I
9/16/25 19:36	9/12/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tabuteau Herriot	NY	DOT	CEO	M.dm	504	8.02	63	1	7,352	D
9/16/25 19:36	9/12/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tabuteau Herriot	NY	DOT	CEO	S.dm	-7,362	117.08	-63	-1	7,352	D
9/16/25 19:05	9/14/25	BTAI	Bioxcel Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mehta Vimal	CT	DO	CEO,P	M.dm	0	0.00	0	0	501	D
9/16/25 19:04	9/14/25	BTAI	Bioxcel Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Steinhart Richard I	CT	O	CFO	M.dm	0	0.00	0	1	7	D
9/16/25 19:02	9/14/25	BTAI	Bioxcel Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rodriguez Javier	CT	O	See Rema	M.dm	0	0.00	0	1	7	D
9/16/25 19:00	9/14/25	BTAI	Bioxcel Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yocca Frank	CT	O	Chief Sc	M.dm	0	0.00	0	1	6	D
9/16/25 18:54	9/15/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rodman David Malcom	PA	O	Chief Me	S	-409	36.00	-11	-12	82	D
9/16/25 18:16	9/16/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Accardi Mario Alberto	X0	O	P,Orexin	S	-175	21.40	-8	-4	197	D
9/16/25 18:09	9/12/25	LBRX	Lb Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Deep Track Biotechnology Master Fund, Ltd.	E9	T		P.d	40,000	15.00	2,667	389	3,353	M
9/16/25 18:06	9/12/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hamilton James C	CA	O	Chief Me	S	-450	30.00	-15	-6	232	D
9/16/25 18:00	9/15/25	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Schneyer Mark C.	CA	O	EVP,CFO	S	-83	23.65	-3	-7	43	D
9/16/25 16:56	9/12/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	O'Neil Patrick R.	CA	O	EVP CLO,	M.d	97	56.78	2	3	57	D
9/16/25 16:56	9/12/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	O'Neil Patrick R.	CA	O	EVP CLO,	S.d	-110	64.58	-2	-3	57	D
9/16/25 16:35	9/15/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Paulson Richard A.	MA	DO	P,CEO	S	-8	6.43	-1	-1	84	D
9/16/25 16:34	9/15/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mano Michael	MA	O	SVP,GC,S	S	-2	6.43	0	-1	21	D
9/16/25 16:33	9/15/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Poulton Stuart	MA	O	EVP,Chie	S	-3	6.43	0	-1	28	D
9/16/25 16:32	9/15/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rangwala Reshma	MA	O	EVP,Chie	S	-3	6.43	0	-1	29	D
9/16/25 16:31	9/15/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cheng Sohanya Roshan	MA	O	EVP,Chie	S	-2	6.43	0	-1	36	D
9/16/25 16:30	9/15/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Abate Kristin	MA	O	Chief Ac	S	0	6.43	0	0	10	D
9/16/25 16:15	9/12/25	ZVRA	Zevra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Favorito Tamara A	FL	D		P	25	7.79	3	442	4	D
9/16/25 16:15	9/12/25	LBRX	Lb Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Pontifax Management 4 G.P. (2015) Ltd.	NY	T		P.d	15,000	15.00	1,000	243	1,412	I
9/16/25 16:15	9/12/25	LBRX	Lb Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Nussbaum Ran	NY	D		P.d	15,000	15.00	1,000	243	1,412	I
9/16/25 15:46	9/12/25	LBRX	Lb Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Vida Ventures Gp Iii, L.L.C.	CA	T		P.d	5,000	15.00	333	61	884	I
9/16/25 07:44	9/12/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	M.dm	962	120.26	8	1	644	D
9/16/25 07:44	9/12/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	S.dm	-3,207	400.93	-8	-1	644	D
9/16/25 06:15	9/15/25	AARD	Aardvark Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lee Tien-Li	CA	DOT	CEO	P	97	9.66	10	0	3,017	D
9/15/25 20:12	9/11/25	CAMP	Camp4 Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	5Am Partners Vi, LLC	CA	T		P	4,500	1.53	2,941	100	5,869	I
9/15/25 19:16	9/12/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Cook Meredith	MN	O	SVP,GC,S	S	-39	98.42	0	-1	76	D
9/15/25 18:37	9/15/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Hussain Iqbal J	X0	O	GC	M.d	35	5.84	6	6	111	D
9/15/25 18:37	9/15/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Hussain Iqbal J	X0	O	GC	S.d	-131	21.85	-6	-5	111	D
9/15/25 17:39	9/12/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mottola Frank	MD	O	SVP,Chie	M.d	197	39.40	5	48	15	D
9/15/25 17:39	9/12/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mottola Frank	MD	O	SVP,Chie	S.d	-229	45.87	-5	-24	15	D
9/15/25 16:47	9/15/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Blum Robert I	CA	DO	P,CEO	S	-249	49.77	-5	-1	377	D
9/15/25 16:26	9/11/25	MRSN	Mersana Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Huber Martin H. Jr.	MA	DO	P,CEO	M.d	0	0.00	7	230	10	D
9/15/25 16:26	9/12/25	MRSN	Mersana Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Huber Martin H. Jr.	MA	DO	P,CEO	S.d	-15	7.31	-2	-17	10	D
9/15/25 16:23	9/12/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Schaeffer Orlov S Nicole	NJ	O	Chief Pe	M.d	1,342	23.75	57		36	D
9/15/25 16:23	9/12/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Schaeffer Orlov S Nicole	NJ	O	Chief Pe	S.d	-11,130	145.45	-77	-68	36	D
9/15/25 16:22	9/12/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Sharoky Melvin Md	NJ	D		S	-1,454	145.39	-10	-3	295	M
9/15/25 16:07	9/12/25	ZVRA	Zevra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Shih Alvin	FL	D		P	158	7.89	20	New	20	D
9/15/25 16:05	9/12/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Huber Reid M	MA	D		P	499	24.48	20	New	20	D
9/15/25 16:05	9/12/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Paul Steven M	MA	D		P	1,027	24.65	42	New	42	I
9/15/25 12:45	9/12/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Callicutt Jack W	GA	O	CFO	M.d	12	1.37	9		8	D
9/15/25 12:45	9/12/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Callicutt Jack W	GA	O	CFO	S.d	-56	6.44	-9	-53	8	D
9/15/25 12:45	9/12/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Lewis Joel	GA	DO	P,CEO	M.d	33	2.39	14	2	835	D
9/15/25 12:45	9/12/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Lewis Joel	GA	DO	P,CEO	S.d	-89	6.36	-14	-2	835	D
9/15/25 12:31	9/12/25	CALC	Calcimedica, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Roberts Eric W	CA	DOT	CHIEF BU	P	16	3.12	5	0	1,058	I
9/12/25 21:45	9/12/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	Todisco Joseph	NJ	O	CEO	M.d	174	3.47	50	11	509	D
9/12/25 21:45	9/12/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	Todisco Joseph	NJ	O	CEO	S.d	-650	13.00	-50	-9	509	D
9/12/25 20:39	9/11/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Young Jonathan	CA	O	COO	S	-25	43.02	-1	0	257	D
9/12/25 20:39	9/11/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yale Catriona	CA	O	Chief De	S	-28	43.02	-1	-1	91	D
9/12/25 20:38	9/11/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	White William Richard	CA	O	CFO	S	-28	43.02	-1	-1	58	D
9/12/25 20:36	9/11/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rolph Timothy	CA	O	Chief Sc	S	-24	43.02	-1	0	167	D
9/12/25 20:36	9/10/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cheng Andrew	CA	DO	P,CEO	M.d	121	8.10	15	3	474	D
9/12/25 20:36	9/10/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cheng Andrew	CA	DO	P,CEO	S.dm	-1,375	43.23	-32	-6	474	D
9/12/25 20:28	9/10/25	AARD	Aardvark Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lee Tien-Li	CA	DOT	CEO	P.m	161	8.03	20	1	3,007	D
9/12/25 20:00	9/11/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Brege Laura	CA	D		M.d	255	15.00	17		16	D
9/12/25 20:00	9/11/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Brege Laura	CA	D		S.d	-1,265	74.40	-17	-52	16	D
9/12/25 20:00	9/11/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bjerkholt Eric	CA	O	CFO	M.d	0	0.00	18	85	40	D
9/12/25 20:00	9/12/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bjerkholt Eric	CA	O	CFO	S.d	-728	76.01	-10	-19	40	D
9/12/25 18:00	9/11/25	VTRS	Viatris Inc	DE	Health	Drug	Pharmaceutical Preparations	Le Goff Corinne	PA	O	Chief Co	S	-72	10.25	-7	-17	35	D
9/12/25 17:30	9/11/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Hariri Robert J	TN	D		M.d	133	2.66	50	999%	51	D
9/12/25 17:30	9/11/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Hariri Robert J	TN	D		S.d	-243	9.71	-25	-33	51	D
9/12/25 17:09	9/11/25	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	Persky Marla	IL	D		S	-120	7.72	-16	-9	148	D
9/12/25 17:09	9/10/25	PMVP	Pmv Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T		S	-900	1.80	-500	-8	5,975	I
9/12/25 16:42	9/11/25	TGTX	Tg Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lonial Sagar	NC	D		S	-672	32.24	-21	-18	94	D
9/12/25 16:38	9/10/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Lee Chan Henry	V8	O	SVP,GC	S.d	-3,257	325.53	-10	-4	238	D
9/12/25 16:38	9/10/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Lee Chan Henry	V8	O	SVP,GC	M.d	1,753	197.10	9	4	238	D
9/12/25 16:32	9/10/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Smiley Joshua L	MA	O	See Rema	P	289	28.91	10	13	87	D
9/12/25 16:30	9/10/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pelish Henry E.	MA	O	Chief Sc	M.d	100	26.94	4	6	66	D
9/12/25 16:30	9/10/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pelish Henry E.	MA	O	Chief Sc	S.d	-294	78.83	-4	-5	66	D
9/12/25 16:30	9/10/25	XOMA	Xoma Royalty Corp	NV	Health	Drug	Pharmaceutical Preparations	Montano Maricel Perea	CA	O	GC	M.d	0	0.00	9	New	9	D
9/12/25 16:11	9/12/25	RARE	Ultragenyx Pharmaceutical Inc.	DE	Health	Drug	Pharmaceutical Preparations	Parschauer Karah Herdman	CA	O	EVP,GC	S	-76	31.17	-2	-3	73	D
9/12/25 16:07	9/11/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Flanagan W. Michael	CA	O	Chief Sc	M.d	284	14.22	20	33	80	D
9/12/25 16:07	9/11/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Flanagan W. Michael	CA	O	Chief Sc	S.d	-779	38.94	-20	-20	80	D
9/12/25 16:01	9/10/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Watson David O.	MA	O	GC	S	-523	26.17	-20	-10	184	I
9/12/25 08:36	8/1/25	CPIX	Cumberland Pharmaceuticals Inc	TN	Health	Drug	Pharmaceutical Preparations	Young Caroline	TN	D		P.m	0	3.29	0	0	33	D
9/12/25 08:35	8/1/25	CPIX	Cumberland Pharmaceuticals Inc	TN	Health	Drug	Pharmaceutical Preparations	Jones James	TN	D		P.m	1	3.29	0	1	44	D
9/12/25 08:34	8/1/25	CPIX	Cumberland Pharmaceuticals Inc	TN	Health	Drug	Pharmaceutical Preparations	Kazimi A J	TN	DOT	CB,CEO	P.m	1	3.29	0	0	5,700	D
9/12/25 08:32	8/1/25	CPIX	Cumberland Pharmaceuticals Inc	TN	Health	Drug	Pharmaceutical Preparations	Krogulski Kenneth	TN	D		P.m	5	3.29	1	0	290	D
9/11/25 21:45	9/9/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	Zelnick Kaufman Beth	NJ	O	GC	M.d	165	3.30	50	38	180	D
9/11/25 21:45	9/9/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	Zelnick Kaufman Beth	NJ	O	GC	S.d	-670	13.41	-50	-22	180	D
9/11/25 21:45	9/9/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hurlburt Elizabeth	NJ	O	COO	M.dm	78	1.45	54	44	177	D
9/11/25 21:45	9/9/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hurlburt Elizabeth	NJ	O	COO	S.dm	-712	13.18	-54	-23	177	D
9/11/25 21:04	9/10/25	IMNM	Immunome Inc.	DE	Health	Drug	Pharmaceutical Preparations	Higgins Jack	WA	O	Chief Sc	M.d	30	1.35	22	117	41	D
9/11/25 21:01	9/9/25	NKTR	Nektar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	Robin Howard W	CA	DO	P,CEO	S	-311	46.69	-7	-12	49	D
9/11/25 20:56	9/9/25	PAHC	Phibro Animal Health Corp	DE	Health	Drug	Pharmaceutical Preparations	Bendheim Jack	NJ	DOT	P,CEO	S.m	-857	40.59	-21	-28	55	I
9/11/25 20:38	9/10/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Swisher Daniel N Jr	CA	D		M.d	31	14.08	2		0	D
9/11/25 20:38	9/10/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Swisher Daniel N Jr	CA	D		S.d	-159	72.45	-2	-100	0	D
9/11/25 19:43	9/9/25	BYSI	Beyondspring Inc.		Health	Drug	Pharmaceutical Preparations	Decheng Capital China Life Sciences Usd Fund Iii, L.P.	CA	T		S.m	-41	1.94	-21	0	4,384	I
9/11/25 19:41	9/10/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	M.dm	962	120.26	8	1	644	D
9/11/25 19:41	9/10/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	S.dm	-3,184	397.97	-8	-1	644	D
9/11/25 19:36	9/10/25	SMMT	Summit Therapeutics Inc.		Health	Drug	Pharmaceutical Preparations	Zanganeh Mahkam	FL	DOT	Co-CEO	P.m	5,985	17.69	338	0	591,832	I
9/11/25 19:32	9/10/25	SMMT	Summit Therapeutics Inc.		Health	Drug	Pharmaceutical Preparations	Duggan Robert W	FL	DOT	Co-CEO	P.m	5,985	17.69	338	0	591,832	D
9/11/25 18:57	9/9/25	LFVN	Lifevantage Corp		Health	Drug	Pharmaceutical Preparations	Beindorff Michael A	UT	D		S	-49	11.44	-4	-3	120	M
9/11/25 18:13	9/11/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Young Wendy B.	MA	D		P	79	22.60	4	58	10	D
9/11/25 18:00	9/10/25	DRRX	Durect Corp	DE	Health	Drug	Pharmaceutical Preparations	Farfel Gail M	CA	D		M.d	7	1.22	6	55	16	D
9/11/25 18:00	9/9/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Quisel John D	MA	DO	CEO	M.d	10	1.01	10	6	172	D
9/11/25 17:52	9/9/25	DRRX	Durect Corp	DE	Health	Drug	Pharmaceutical Preparations	Brown James E	CA	DO	P,CEO	M.dm	341	1.30	262	90	553	D
9/11/25 17:50	9/9/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Bush Tia L	X0	O	Chief Te	M.dm	434	8.72	50	69	122	D
9/11/25 17:50	9/9/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Bush Tia L	X0	O	Chief Te	S.dm	-1,046	21.00	-50	-29	122	D
9/11/25 17:50	9/10/25	DRRX	Durect Corp	DE	Health	Drug	Pharmaceutical Preparations	Robertson Judith J.	CA	D		M.d	7	1.22	6	15	41	D
9/11/25 17:48	9/9/25	DRRX	Durect Corp	DE	Health	Drug	Pharmaceutical Preparations	Garcia Peter S	CA	D		M.d	7	1.22	6	79	13	D
9/11/25 17:47	9/9/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Hussain Iqbal J	X0	O	GC	M.dm	234	5.84	40	56	111	D
9/11/25 17:47	9/9/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Hussain Iqbal J	X0	O	GC	S.dm	-840	21.00	-40	-27	111	D
9/11/25 17:45	9/9/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Accardi Mario Alberto	X0	O	P,Orexin	M.d	40	8.01	5	2	206	D
9/11/25 17:45	9/9/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Accardi Mario Alberto	X0	O	P,Orexin	S.d	-140	20.00	-7	-3	206	D
9/11/25 17:20	9/9/25	DNTH	Dianthus Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	Savitz Ryan	NY	O	CFO,CBO	M.d	169	8.44	20		0	D
9/11/25 17:20	9/9/25	DNTH	Dianthus Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	Savitz Ryan	NY	O	CFO,CBO	S.d	-700	35.00	-20	-100	0	D
9/11/25 17:10	9/9/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Wang Lai	V8	O	Global H	S	-1,750	350.06	-5	0	1,625	I
9/11/25 17:05	9/9/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Baroldi Joseph	CA	O	EVP,Chie	M.d	380	31.80	12	52	35	D
9/11/25 17:05	9/9/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Baroldi Joseph	CA	O	EVP,Chie	S.d	-743	62.16	-12	-25	35	D
9/11/25 17:04	9/9/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	O'Neil Patrick R.	CA	O	EVP CLO,	M.d	1,275	60.69	21	58	57	D
9/11/25 17:04	9/9/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	O'Neil Patrick R.	CA	O	EVP CLO,	S.d	-1,356	64.56	-21	-27	57	D
9/11/25 17:00	9/9/25	PRGO	Perrigo Co Plc	L2	Health	Drug	Pharmaceutical Preparations	Ball David	MI	O	EVP,CBDO	M.d	172	22.28	8		5	D
9/11/25 16:59	9/11/25	CAMP	Camp4 Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Polaris Management Co. Vii, L.L.C.	MA	T		P	2,000	1.53	1,307		1,107	I
9/11/25 16:48	9/11/25	CAMP	Camp4 Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Nashat Amir	MA	DT		P	2,000	1.53	1,307		1,107	I
9/11/25 16:25	9/11/25	CAMP	Camp4 Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Maricich Yuri	MA	O	Chief Me	P	10	1.65	6	New	6	D
9/11/25 16:24	9/11/25	CAMP	Camp4 Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Gold Kelly	MA	O	CFO	P	10	1.65	6	10	68	D
9/11/25 16:23	9/11/25	CAMP	Camp4 Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mandel-Brehm Josh	MA	DO	CEO	P	10	1.65	6	2	278	D
9/11/25 16:22	9/11/25	CAMP	Camp4 Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Young Richard A	MA	D		P	25	1.65	15	10	170	D
9/11/25 16:16	9/10/25	BSPK	Bespoke Extracts, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Feinsod Michael	NY	DOT	CEO	P.m	1	0.2243	4	0	2,512	D
9/11/25 16:05	9/9/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Reitan Colleen F	MA	D		M.d	1,812	100.65	18		1	D
9/11/25 16:05	9/9/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Reitan Colleen F	MA	D		S.d	-8,417	467.60	-18	-96	1	D
9/11/25 13:14	9/9/25	DRRX	Durect Corp	DE	Health	Drug	Pharmaceutical Preparations	Maderis Gail J	CA	D		M.d	7	1.22	6	28	26	D
9/11/25 12:00	9/9/25	CALC	Calcimedica, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Roberts Eric W	CA	DOT	CHIEF BU	P	7	3.15	2	0	1,053	I
9/10/25 21:23	9/8/25	DRRX	Durect Corp	DE	Health	Drug	Pharmaceutical Preparations	Brown James E	CA	DO	P,CEO	M.d	13	1.30	10	4	283	D
9/10/25 20:12	9/8/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Patel Anish	CO	O	COO	S	-135	20.24	-7	-2	283	I
9/10/25 19:48	9/8/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rolph Timothy	CA	O	Chief Sc	M.d	190	15.18	13	8	167	D
9/10/25 19:48	9/8/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rolph Timothy	CA	O	Chief Sc	S.d	-552	44.17	-13	-7	167	D
9/10/25 18:21	9/8/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Watanabe Todd	CA	DO	See Rema	S.m	-178	17.54	-10	-1	1,125	D
9/10/25 17:50	9/8/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ramasastry Saira	CA	D		M.d	400	23.51	17		0	D
9/10/25 17:50	9/8/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ramasastry Saira	CA	D		S.d	0	0.00	-17	-100	0	D
9/10/25 17:39	9/9/25	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	Kooij Louise Frederika	P7	O	Chief Ac	M.d	1,500	10.00	150		15	D
9/10/25 17:39	9/9/25	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	Kooij Louise Frederika	P7	O	Chief Ac	S.d	-3,874	25.83	-150	-91	15	D
9/10/25 17:36	9/9/25	AARD	Aardvark Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sun Nelson	CA	O	CFO	P	48	8.07	6	6	105	D
9/10/25 17:19	9/8/25	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	Topper James N	CA	D		P	31	24.99	1	0	6,829	I
9/10/25 17:00	9/8/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Elsbernd Brian	FL	O	Chief Co	M.d	252	2.24	112	71	271	D
9/10/25 17:00	9/8/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Elsbernd Brian	FL	O	Chief Co	S.d	-609	20.30	-30	-10	271	D
9/10/25 16:31	9/8/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Benkowitz Michael	MD	O	P,COO	M.dm	5,216	318.55	16		3	I
9/10/25 16:31	9/8/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Benkowitz Michael	MD	O	P,COO	S.dm	-6,482	395.82	-16	-86	3	I
9/10/25 16:31	9/9/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Malcolm Jan	MD	D		S	-280	400.29	-1	-57	1	D
9/10/25 16:31	9/9/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	M.d	962	120.26	8	1	644	D
9/10/25 16:31	9/9/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	S.d	-3,188	398.55	-8	-1	644	D
9/10/25 16:30	9/10/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Thompson Tommy G	MD	D		M.d	1,048	229.81	5	25	22	D
9/10/25 16:30	9/10/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Thompson Tommy G	MD	D		S.d	-1,839	403.36	-5	-17	22	D
9/10/25 16:19	9/8/25	PRGO	Perrigo Co Plc	L2	Health	Drug	Pharmaceutical Preparations	Lennox Abigail	MI	O	EVP, CSO	P	28	22.41	1	New	1	D
9/10/25 16:15	9/8/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gault Cheryl	MA	O	COO	M.d	9	1.80	5	3	172	D
9/10/25 16:15	9/8/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gault Cheryl	MA	O	COO	S.d	-192	38.33	-5	-3	172	D
9/10/25 16:13	9/9/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Malik Fady Ibraham	CA	O	EVP Rese	M.d	21	10.60	2	1	141	D
9/10/25 16:13	9/9/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Malik Fady Ibraham	CA	O	EVP Rese	S.d	-103	51.29	-2	-1	141	D
9/10/25 16:02	9/8/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sullivan Timothy Eugene	MA	O	CFO	M.d	150	10.03	15	10	171	M
9/10/25 16:02	9/8/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sullivan Timothy Eugene	MA	O	CFO	S.d	-1,190	27.85	-43	-20	171	M
9/10/25 15:09	9/5/25	CYCC	Cyclacel Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kua Khai Loon	N8	T		S	-134	7.01	-19	-5	385	D
9/9/25 21:07	9/9/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sibold William John	PA	DO	P,CEO	S	-3,244	445.63	-7	-7	102	D
9/9/25 20:11	9/8/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Coleman Mark	NY	D		P	200	127.28	2	0	452	D
9/9/25 19:17	9/8/25	DRRX	Durect Corp	DE	Health	Drug	Pharmaceutical Preparations	Papp Timothy M.	CA	O	CFO	M.d	143	1.30	110	34	432	D
9/9/25 19:02	9/6/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Palleiko Benjamin L	MA	DO	CEO	M.d	0	0.00	16	4	395	D
9/9/25 19:02	9/8/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Palleiko Benjamin L	MA	DO	CEO	S.d	-116	15.84	-7	-2	395	D
9/9/25 18:37	9/7/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Schoenberg Mark	NJ	O	Chief Me	M.d	0	0.00	2	1	149	D
9/9/25 18:37	9/8/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Schoenberg Mark	NJ	O	Chief Me	S.d	-17	19.11	-1	-1	149	D
9/9/25 18:32	9/7/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Smith Jason Drew	NJ	O	GC	M.d	0	0.00	3	8	43	D
9/9/25 18:32	9/8/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Smith Jason Drew	NJ	O	GC	S.d	-29	19.11	-2	-3	43	D
9/9/25 18:30	9/5/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Baroldi Joseph	CA	O	EVP,Chie	M.d	8	31.80	0	1	35	D
9/9/25 18:30	9/5/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Baroldi Joseph	CA	O	EVP,Chie	S.d	-16	62.00	0	-1	35	D
9/9/25 18:30	9/5/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	EVP,Chie	S	-358	59.60	-6	-7	83	D
9/9/25 17:53	9/5/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Wilson Troy Edward	CA	D		M.d	181	12.48	15	27	68	D
9/9/25 17:53	9/5/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Wilson Troy Edward	CA	D		S.d	-1,475	50.00	-30	-30	68	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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