12/19/25 21:30 | 12/18/25 | CRMD | Cormedix Inc. | DE | Health | Drug | Pharmaceutical Preparations | Todisco Joseph | NJ | DO | CEO | M.d | 133 | 4.43 | 0 | 30 | 6 | 509 | D | | | | | | | | | | | | | | |
12/19/25 21:30 | 12/18/25 | CRMD | Cormedix Inc. | DE | Health | Drug | Pharmaceutical Preparations | Todisco Joseph | NJ | DO | CEO | S.d | -360 | 12.00 | 0 | -30 | -6 | 509 | D | | | | | | | | | | | | | | |
12/19/25 21:04 | 12/17/25 | ROIV | Roivant Sciences Ltd. | D0 | Health | Drug | Pharmaceutical Preparations | Sukhatme Mayukh | X0 | DO | P,CIO | M.d | 755 | 12.68 | 0 | 60 | 0 | 18,837 | D | | | | | | | | | | | | | | |
12/19/25 21:04 | 12/17/25 | ROIV | Roivant Sciences Ltd. | D0 | Health | Drug | Pharmaceutical Preparations | Sukhatme Mayukh | X0 | DO | P,CIO | S.d | -620 | 23.09 | 0 | -27 | 0 | 18,837 | D | | | | | | | | | | | | | | |
12/19/25 21:00 | 12/19/25 | TYRA | Tyra Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | More Robert J | CA | D | | S | -250 | 25.00 | 0 | -10 | 0 | 3,823 | I | | | | | | | | | | | | | | |
12/19/25 20:00 | 12/17/25 | MNKD | Mannkind Corp | DE | Health | Drug | Pharmaceutical Preparations | Castagna Michael | CT | DO | CEO | M.d | 299 | 4.55 | 0 | 66 | 3 | 2,505 | D | | | | | | | | | | | | | | |
12/19/25 20:00 | 12/17/25 | MNKD | Mannkind Corp | DE | Health | Drug | Pharmaceutical Preparations | Castagna Michael | CT | DO | CEO | S.d | -395 | 6.01 | 0 | -66 | -3 | 2,505 | D | | | | | | | | | | | | | | |
12/19/25 19:29 | 12/17/25 | SION | Sionna Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D | | S.m | -83 | 44.49 | 0 | -2 | 0 | 3,595 | I | | | | | | | | | | | | | | |
12/19/25 19:24 | 12/17/25 | SION | Sionna Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Thompson Peter A. | MA | D | | S.m | -83 | 44.49 | 0 | -2 | 0 | 3,595 | I | | | | | | | | | | | | | | |
12/19/25 19:21 | 12/17/25 | HYPD | Hyperion Defi, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Walters Happy David | CA | D | | P | 187 | 3.02 | 0 | 62 | 124 | 112 | D | | | | | | | | | | | | | | |
12/19/25 18:56 | 12/17/25 | ARWR | Arrowhead Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Anzalone Christopher Richard | CA | DO | CEO | S | -5,443 | 64.04 | 0 | -85 | -2 | 3,832 | D | | | | | | | | | | | | | | |
12/19/25 18:16 | 12/19/25 | IRON | Disc Medicine, Inc. | | Health | Drug | Pharmaceutical Preparations | Quisel John D | MA | DO | CEO | M.d | 12 | 1.01 | 0 | 12 | 7 | 184 | D | | | | | | | | | | | | | | |
12/19/25 17:58 | 12/17/25 | ELVN | Enliven Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kunkel Lori Anne | CO | D | | M.d | 18 | 1.12 | 0 | 16 | 35 | 62 | D | | | | | | | | | | | | | | |
12/19/25 17:38 | 12/19/25 | ORKA | Oruka Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Goncalves Joana | CA | O | Chief Me | M.d | 51 | 7.32 | 0 | 7 | | 2 | D | | | | | | | | | | | | | | |
12/19/25 17:38 | 12/19/25 | ORKA | Oruka Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Goncalves Joana | CA | O | Chief Me | S.d | -214 | 30.61 | 0 | -7 | -82 | 2 | D | | | | | | | | | | | | | | |
12/19/25 17:24 | 12/17/25 | RPRX | Royalty Pharma Plc | X0 | Health | Drug | Pharmaceutical Preparations | Lloyd George W. | NY | O | EVP,Inve | S.m | -4,240 | 38.55 | 0 | -110 | -12 | 780 | I | | | | | | | | | | | | | | |
12/19/25 17:17 | 12/19/25 | XERS | Xeris Biopharma Holdings, Inc. | | Health | Drug | Pharmaceutical Preparations | Johnson John | IL | D | | S | -977 | 7.22 | 0 | -135 | -16 | 698 | D | | | | | | | | | | | | | | |
12/19/25 17:00 | 12/19/25 | SVRA | Savara Inc | DE | Health | Drug | Pharmaceutical Preparations | Ramsay David A | PA | D | | S | -121 | 6.06 | 0 | -20 | -1 | 2,534 | D | | | | | | | | | | | | | | |
12/19/25 17:00 | 12/17/25 | ADTX | Aditxt, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Brady Brian Michael | CA | D | | S | 0 | 1.75 | 0 | 0 | -25 | 0 | D | | | | | | | | | | | | | | |
12/19/25 16:47 | 12/18/25 | ANIP | Ani Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Davis Krista | MN | O | SVP,CHRO | S | -134 | 82.40 | 0 | -2 | -3 | 59 | D | | | | | | | | | | | | | | |
12/19/25 16:31 | 12/18/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Thompson Tommy G | MD | D | | M.d | 93 | 101.80 | 0 | 1 | 4 | 22 | D | | | | | | | | | | | | | | |
12/19/25 16:31 | 12/18/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Thompson Tommy G | MD | D | | S.d | -456 | 500.59 | 0 | -1 | -4 | 22 | D | | | | | | | | | | | | | | |
12/19/25 16:30 | 12/17/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Rothblatt Martine A | MD | DO | CHAIRPER | M.dm | 1,203 | 120.26 | 0 | 10 | 2 | 639 | D | | | | | | | | | | | | | | |
12/19/25 16:30 | 12/17/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Rothblatt Martine A | MD | DO | CHAIRPER | S.dm | -5,054 | 505.38 | 0 | -10 | -2 | 639 | D | | | | | | | | | | | | | | |
12/19/25 16:30 | 12/18/25 | KURA | Kura Oncology, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Burrows Francis | CA | O | Chief Sc | M.d | 168 | 4.80 | 0 | 35 | | 34 | D | | | | | | | | | | | | | | |
12/19/25 16:30 | 12/18/25 | KURA | Kura Oncology, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Burrows Francis | CA | O | Chief Sc | S.d | -232 | 9.78 | 0 | -24 | -41 | 34 | D | | | | | | | | | | | | | | |
12/19/25 16:15 | 12/18/25 | MIRM | Mirum Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Ramasastry Saira | CA | D | | M.d | 47 | 23.51 | 0 | 2 | | 0 | D | | | | | | | | | | | | | | |
12/19/25 16:15 | 12/18/25 | MIRM | Mirum Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Ramasastry Saira | CA | D | | S.d | -139 | 69.73 | 0 | -2 | -100 | 0 | D | | | | | | | | | | | | | | |
12/19/25 16:15 | 12/17/25 | VTYX | Ventyx Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Mohan Raju | CA | DO | CEO,P | M.d | 0 | 0.00 | 0 | 117 | 5 | 2,373 | D | | | | | | | | | | | | | | |
12/19/25 16:15 | 12/18/25 | VTYX | Ventyx Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Mohan Raju | CA | DO | CEO,P | S.d | -365 | 7.72 | 0 | -47 | -2 | 2,373 | D | | | | | | | | | | | | | | |
12/19/25 16:15 | 12/17/25 | VTYX | Ventyx Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Nuss John | CA | O | Chief Sc | M.d | 0 | 0.00 | 0 | 35 | 8 | 489 | D | | | | | | | | | | | | | | |
12/19/25 16:15 | 12/18/25 | VTYX | Ventyx Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Nuss John | CA | O | Chief Sc | S.d | -98 | 7.72 | 0 | -13 | -3 | 489 | D | | | | | | | | | | | | | | |
12/19/25 16:12 | 12/18/25 | INSM | Insmed Inc | VA | Health | Drug | Pharmaceutical Preparations | Lewis William | NJ | DO | Chair,CE | M.d | 267 | 24.94 | 0 | 11 | 2 | 588 | D | | | | | | | | | | | | | | |
12/19/25 16:12 | 12/18/25 | INSM | Insmed Inc | VA | Health | Drug | Pharmaceutical Preparations | Lewis William | NJ | DO | Chair,CE | S.d | -1,786 | 166.97 | 0 | -11 | -2 | 588 | D | | | | | | | | | | | | | | |
12/19/25 16:08 | 12/17/25 | GALT | Galectin Therapeutics Inc | NV | Health | Drug | Pharmaceutical Preparations | Lewis Joel | GA | DO | P,CEO | M.d | 22 | 2.86 | 0 | 8 | 1 | 835 | D | | | | | | | | | | | | | | |
12/19/25 16:08 | 12/17/25 | GALT | Galectin Therapeutics Inc | NV | Health | Drug | Pharmaceutical Preparations | Lewis Joel | GA | DO | P,CEO | S.d | -55 | 7.06 | 0 | -8 | -1 | 835 | D | | | | | | | | | | | | | | |
12/19/25 16:06 | 12/17/25 | GALT | Galectin Therapeutics Inc | NV | Health | Drug | Pharmaceutical Preparations | Jamil Khurram | GA | O | Chief Me | S.d | -137 | 7.04 | 0 | -19 | -100 | 0 | D | | | | | | | | | | | | | | |
12/19/25 16:06 | 12/17/25 | GALT | Galectin Therapeutics Inc | NV | Health | Drug | Pharmaceutical Preparations | Jamil Khurram | GA | O | Chief Me | M.d | 35 | 2.37 | 0 | 15 | | 0 | D | | | | | | | | | | | | | | |
12/19/25 16:05 | 12/18/25 | SUPN | Supernus Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Bhatt Padmanabh P. | MD | O | SVP of I | M.d | 0 | 0.00 | 0 | 2 | 12 | 15 | D | | | | | | | | | | | | | | |
12/19/25 16:05 | 12/18/25 | SUPN | Supernus Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Bhatt Padmanabh P. | MD | O | SVP of I | S.d | -32 | 44.44 | 0 | -1 | -5 | 15 | D | | | | | | | | | | | | | | |
12/19/25 16:05 | 12/17/25 | SLGL | Sol-Gel Technologies Ltd. | L3 | Health | Drug | Pharmaceutical Preparations | Opaleye Management Inc. | MA | T | | P | 110 | 40.37 | 0 | 3 | 1 | 385 | I | | | | | | | | | | | | | | |
12/19/25 16:05 | 12/17/25 | PVLA | Palvella Therapeutics, Inc. | NV | Health | Drug | Pharmaceutical Preparations | Goin Kathleen | PA | O | COO | M.d | 35 | 8.11 | 0 | 4 | | 0 | D | | | | | | | | | | | | | | |
12/19/25 16:05 | 12/17/25 | PVLA | Palvella Therapeutics, Inc. | NV | Health | Drug | Pharmaceutical Preparations | Goin Kathleen | PA | O | COO | S.d | -415 | 96.47 | 0 | -4 | -100 | 0 | D | | | | | | | | | | | | | | |
12/19/25 16:05 | 12/17/25 | GALT | Galectin Therapeutics Inc | NV | Health | Drug | Pharmaceutical Preparations | Shlevin Harold H. | GA | D | | M.d | 40 | 1.98 | 0 | 20 | | 7 | D | | | | | | | | | | | | | | |
12/19/25 16:05 | 12/17/25 | GALT | Galectin Therapeutics Inc | NV | Health | Drug | Pharmaceutical Preparations | Shlevin Harold H. | GA | D | | S.d | -172 | 7.04 | 0 | -24 | -79 | 7 | D | | | | | | | | | | | | | | |
12/19/25 15:43 | 12/18/25 | MNPR | Monopar Therapeutics | DE | Health | Drug | Pharmaceutical Preparations | Klausner Arthur J | IL | D | | S | -344 | 67.15 | 0 | -5 | -37 | 9 | D | | | | | | | | | | | | | | |
12/19/25 11:00 | 12/17/25 | HYPD | Hyperion Defi, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Geltzeiler Michael S | CA | D | | P | 90 | 3.01 | 0 | 30 | 52 | 88 | D | | | | | | | | | | | | | | |
12/19/25 07:00 | 12/17/25 | RNXT | Renovorx, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Bagai Shaun | CA | DO | CEO | P | 4 | 0.8524 | 0 | 5 | 2 | 335 | D | | | | | | | | | | | | | | |
12/19/25 06:05 | 12/18/25 | GLSI | Greenwich Lifesciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Patel Snehal | TX | DOT | CEO,CFO | P | 52 | 12.62 | 0 | 4 | 0 | 5,592 | D | | | | | | | | | | | | | | |
12/18/25 20:05 | 12/16/25 | SRPT | Sarepta Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Estepan Ian Michael | MA | O | COO | S | -294 | 22.31 | 0 | -13 | -6 | 193 | D | | | | | | | | | | | | | | |
12/18/25 19:54 | 12/16/25 | ROIV | Roivant Sciences Ltd. | D0 | Health | Drug | Pharmaceutical Preparations | Gold Daniel Allen | X0 | D | | S.m | -39,065 | 23.05 | 0 | -1,695 | -9 | 16,353 | I | | | | | | | | | | | | | | |
12/18/25 19:52 | 12/16/25 | ROIV | Roivant Sciences Ltd. | D0 | Health | Drug | Pharmaceutical Preparations | Manchester Keith S | X0 | D | | S.m | -39,065 | 23.05 | 0 | -1,695 | -9 | 16,353 | I | | | | | | | | | | | | | | |
12/18/25 19:41 | 12/16/25 | ROIV | Roivant Sciences Ltd. | D0 | Health | Drug | Pharmaceutical Preparations | Qvt Financial LP | NY | H | Director | S.m | -39,065 | 23.05 | 0 | -1,695 | -9 | 16,353 | I | | | | | | | | | | | | | | |
12/18/25 18:54 | 12/18/25 | CRNX | Crinetics Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Struthers Richard Scott | CA | DO | P,CEO | M.d | 586 | 13.09 | 0 | 45 | 3 | 1,343 | D | | | | | | | | | | | | | | |
12/18/25 18:14 | 12/17/25 | IRON | Disc Medicine, Inc. | | Health | Drug | Pharmaceutical Preparations | Bitterman Kevin | MA | D | | S | -69 | 91.47 | 0 | -1 | -5 | 14 | I | | | | | | | | | | | | | | |
12/18/25 18:08 | 12/18/25 | NRIX | Nurix Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Ring Christine | CA | O | GC | M.d | 7 | 1.86 | 0 | 4 | 8 | 51 | D | | | | | | | | | | | | | | |
12/18/25 18:08 | 12/18/25 | NRIX | Nurix Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Ring Christine | CA | O | GC | S.d | -67 | 17.90 | 0 | -4 | -7 | 51 | D | | | | | | | | | | | | | | |
12/18/25 18:02 | 12/16/25 | BCAX | Bicara Therapeutics Inc. | DE | Health | Drug | Pharmaceutical Preparations | Mazumdar Claire | MA | DO | CEO | M.d | 161 | 5.45 | 0 | 30 | 10 | 339 | D | | | | | | | | | | | | | | |
12/18/25 17:54 | 12/16/25 | MRUS | Merus N.V. | P7 | Health | Drug | Pharmaceutical Preparations | Genmab A/S | G7 | T | | P.m | 26,340 | 97.00 | 0 | 272 | 0 | 71,735 | I | | | | | | | | | | | | | | |
12/18/25 17:35 | 12/16/25 | RCUS | Arcus Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Tang Carolyn C. | CA | O | GC | S.m | -318 | 22.01 | 0 | -14 | -10 | 125 | D | | | | | | | | | | | | | | |
12/18/25 17:35 | 12/16/25 | RCUS | Arcus Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Markus Richard | CA | O | Chief Me | S.m | -210 | 22.01 | 0 | -10 | -13 | 66 | D | | | | | | | | | | | | | | |
12/18/25 17:35 | 12/16/25 | RCUS | Arcus Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Azoy Alexander | CA | O | Chief Ac | S.m | -195 | 22.13 | 0 | -9 | -32 | 19 | D | | | | | | | | | | | | | | |
12/18/25 17:35 | 12/16/25 | RCUS | Arcus Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Goeltz II Robert C. | CA | O | CFO | S.m | -279 | 22.01 | 0 | -13 | -15 | 74 | D | | | | | | | | | | | | | | |
12/18/25 17:35 | 12/16/25 | RCUS | Arcus Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Jarrett Jennifer | CA | O | COO | S.m | -467 | 22.01 | 0 | -21 | -10 | 193 | D | | | | | | | | | | | | | | |
12/18/25 17:35 | 12/16/25 | RCUS | Arcus Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Jaen Juan C. | CA | O | P | S.m | -467 | 22.01 | 0 | -21 | -2 | 1,300 | D | | | | | | | | | | | | | | |
12/18/25 17:35 | 12/16/25 | RCUS | Arcus Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Rosen Terry J | CA | DO | CEO | S.m | -1,204 | 22.01 | 0 | -55 | -2 | 2,195 | D | | | | | | | | | | | | | | |
12/18/25 17:23 | 12/17/25 | AMPH | Amphastar Pharmaceuticals, Inc. | | Health | Drug | Pharmaceutical Preparations | Zhou Rong | CA | O | SENIOR E | M.d | 111 | 11.33 | 0 | 10 | 4 | 243 | D | | | | | | | | | | | | | | |
12/18/25 17:23 | 12/17/25 | AMPH | Amphastar Pharmaceuticals, Inc. | | Health | Drug | Pharmaceutical Preparations | Zhou Rong | CA | O | SENIOR E | S.d | -256 | 26.20 | 0 | -10 | -4 | 243 | D | | | | | | | | | | | | | | |
12/18/25 17:08 | 12/3/25 | CLNN | Clene Inc. | DE | Health | Drug | Pharmaceutical Preparations | Ugwumba Chidozie | AR | T | | S.m | -1,726 | 6.69 | 0 | -258 | -40 | 393 | I | | | | | | | | | | | | | | |
12/18/25 17:03 | 12/18/25 | IMNM | Immunome Inc. | DE | Health | Drug | Pharmaceutical Preparations | Siegall Clay B | WA | DO | P,CEO | P | 1,000 | 21.50 | 0 | 47 | 6 | 853 | D | | | | | | | | | | | | | | |
12/18/25 16:47 | 12/16/25 | VSTM | Verastem, Inc. | MA | Health | Drug | Pharmaceutical Preparations | Stuglik Brian M | MA | D | | S | -5 | 9.14 | 0 | -1 | -1 | 101 | D | | | | | | | | | | | | | | |
12/18/25 16:46 | 12/16/25 | VSTM | Verastem, Inc. | MA | Health | Drug | Pharmaceutical Preparations | Paterson Dan | MA | DO | P,CEO | S | -4 | 9.14 | 0 | 0 | 0 | 410 | D | | | | | | | | | | | | | | |
12/18/25 16:45 | 12/16/25 | VSTM | Verastem, Inc. | MA | Health | Drug | Pharmaceutical Preparations | Gagnon Robert E. | MA | D | | S | -3 | 9.14 | 0 | 0 | -1 | 42 | D | | | | | | | | | | | | | | |
12/18/25 16:34 | 12/16/25 | ZLAB | Zai Lab Ltd | E9 | Health | Drug | Pharmaceutical Preparations | Edmondson Frazor Titus III | MA | O | GC | S | -148 | 17.14 | 0 | -9 | -31 | 19 | D | | | | | | | | | | | | | | |
12/18/25 16:19 | 12/16/25 | LGND | Ligand Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Espinoza Octavio | FL | O | CFO | M.d | 164 | 69.00 | 0 | 2 | 9 | 29 | D | | | | | | | | | | | | | | |
12/18/25 16:19 | 12/16/25 | ORGO | Organogenesis Holdings Inc. | DE | Health | Drug | Pharmaceutical Preparations | Nussdorf Glenn H | NY | D | | S | -1,027 | 5.14 | 0 | -200 | -2 | 11,749 | D | | | | | | | | | | | | | | |
12/18/25 16:14 | 12/16/25 | ANAB | Anaptysbio, Inc | DE | Health | Drug | Pharmaceutical Preparations | Loumeau Eric J | CA | O | GC | M.dm | 362 | 16.07 | 0 | 23 | | 9 | D | | | | | | | | | | | | | | |
12/18/25 16:14 | 12/16/25 | ANAB | Anaptysbio, Inc | DE | Health | Drug | Pharmaceutical Preparations | Loumeau Eric J | CA | O | GC | S.dm | -1,027 | 45.38 | 0 | -23 | -72 | 9 | D | | | | | | | | | | | | | | |
12/18/25 16:13 | 12/16/25 | ANAB | Anaptysbio, Inc | DE | Health | Drug | Pharmaceutical Preparations | Mulroy Dennis | CA | O | CFO | M.d | 202 | 20.16 | 0 | 10 | | 9 | D | | | | | | | | | | | | | | |
12/18/25 16:13 | 12/16/25 | ANAB | Anaptysbio, Inc | DE | Health | Drug | Pharmaceutical Preparations | Mulroy Dennis | CA | O | CFO | S.d | -705 | 44.85 | 0 | -16 | -63 | 9 | D | | | | | | | | | | | | | | |
12/18/25 16:11 | 12/17/25 | RAPP | Rapport Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Ceesay Abraham | MA | DO | CEO | S | -324 | 29.64 | 0 | -11 | -2 | 681 | M | | | | | | | | | | | | | | |
12/18/25 16:10 | 12/17/25 | ESPR | Esperion Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Koenig Sheldon L. | MI | DO | P,CEO | S | -177 | 3.67 | 0 | -48 | -3 | 1,471 | D | | | | | | | | | | | | | | |
12/18/25 16:09 | 12/17/25 | ESPR | Esperion Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Halladay Benjamin | MI | O | CFO | S | -27 | 3.67 | 0 | -7 | -2 | 468 | D | | | | | | | | | | | | | | |
12/18/25 16:09 | 12/17/25 | ESPR | Esperion Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Looker Benjamin | MI | O | GC | S | -24 | 3.67 | 0 | -7 | -2 | 386 | D | | | | | | | | | | | | | | |
12/18/25 16:06 | 12/16/25 | APLS | Apellis Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Watson David O. | MA | O | GC | S | -122 | 24.49 | 0 | -5 | -3 | 164 | D | | | | | | | | | | | | | | |
12/18/25 16:04 | 12/16/25 | TEVA | Teva Pharmaceutical Industries Ltd | L3 | Health | Drug | Pharmaceutical Preparations | Weiss Amir | L3 | O | Chief Ac | S | -372 | 30.20 | 0 | -12 | -69 | 6 | D | | | | | | | | | | | | | | |
12/18/25 16:02 | 12/16/25 | TEVA | Teva Pharmaceutical Industries Ltd | L3 | Health | Drug | Pharmaceutical Preparations | Mignone Roberto | L3 | D | | S | -2,341 | 30.24 | 0 | -77 | -14 | 473 | I | | | | | | | | | | | | | | |
12/18/25 15:13 | 12/16/25 | APLT | Applied Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kanter Stacy J. | NY | D | | S | -5 | 0.1120 | 0 | -43 | -40 | 65 | D | | | | | | | | | | | | | | |
12/18/25 10:34 | 12/16/25 | GALT | Galectin Therapeutics Inc | NV | Health | Drug | Pharmaceutical Preparations | 10X Fund, L.P. | GA | T | | S | -204 | 6.66 | 0 | -31 | -1 | 5,614 | D | | | | | | | | | | | | | | |
12/17/25 21:00 | 12/15/25 | ROIV | Roivant Sciences Ltd. | D0 | Health | Drug | Pharmaceutical Preparations | Gline Matthew | X0 | DO | CEO | M.d | 47,062 | 12.16 | 0 | 3,871 | 29 | 17,287 | D | | | | | | | | | | | | | | |
12/17/25 21:00 | 12/15/25 | ROIV | Roivant Sciences Ltd. | D0 | Health | Drug | Pharmaceutical Preparations | Gline Matthew | X0 | DO | CEO | S.d | -37,723 | 21.68 | 0 | -1,740 | -9 | 17,287 | D | | | | | | | | | | | | | | |
12/17/25 19:56 | 12/16/25 | SER | Serina Therapeutics, Inc. | AL | Health | Drug | Pharmaceutical Preparations | Moreadith Randall | AL | O | Chief Sc | M.d | 0 | 0.0600 | 0 | 3 | | 0 | D | | | | | | | | | | | | | | |
12/17/25 19:56 | 12/16/25 | SER | Serina Therapeutics, Inc. | AL | Health | Drug | Pharmaceutical Preparations | Moreadith Randall | AL | O | Chief Sc | S.d | -10 | 2.96 | 0 | -3 | -100 | 0 | D | | | | | | | | | | | | | | |
12/17/25 19:21 | 12/15/25 | ORIC | Oric Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Multani Pratik S | CA | O | Chief Me | M.d | 0 | 0.00 | 0 | 29 | 76 | 68 | D | | | | | | | | | | | | | | |
12/17/25 19:21 | 12/16/25 | ORIC | Oric Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Multani Pratik S | CA | O | Chief Me | S.d | -97 | 9.06 | 0 | -11 | -14 | 68 | D | | | | | | | | | | | | | | |
12/17/25 19:19 | 12/15/25 | ORIC | Oric Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Piscitelli Dominic | CA | O | CFO | M.d | 0 | 0.00 | 0 | 29 | 76 | 68 | D | | | | | | | | | | | | | | |
12/17/25 19:19 | 12/16/25 | ORIC | Oric Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Piscitelli Dominic | CA | O | CFO | S.d | -97 | 9.06 | 0 | -11 | -14 | 68 | D | | | | | | | | | | | | | | |
12/17/25 19:18 | 12/15/25 | ORIC | Oric Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Chacko Jacob | CA | DO | P,CEO | M.d | 0 | 0.00 | 0 | 84 | 17 | 582 | D | | | | | | | | | | | | | | |
12/17/25 19:18 | 12/16/25 | ORIC | Oric Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Chacko Jacob | CA | DO | P,CEO | S.d | -302 | 9.06 | 0 | -33 | -5 | 582 | D | | | | | | | | | | | | | | |
12/17/25 18:28 | 12/15/25 | HOWL | Werewolf Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Evnin Luke | MA | D | | S.m | -52 | 1.08 | 0 | -48 | -2 | 2,842 | I | | | | | | | | | | | | | | |
12/17/25 18:21 | 12/15/25 | FOLD | Amicus Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Campbell Bradley L | NJ | DO | P,CEO | M.d | 636 | 9.03 | 0 | 70 | 7 | 1,130 | D | | | | | | | | | | | | | | |
12/17/25 18:21 | 12/15/25 | FOLD | Amicus Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Campbell Bradley L | NJ | DO | P,CEO | S.d | -846 | 10.86 | 0 | -78 | -6 | 1,130 | D | | | | | | | | | | | | | | |
12/17/25 18:19 | 12/15/25 | FOLD | Amicus Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Clark David Michael | NJ | O | Chief Pe | S | -282 | 11.00 | 0 | -26 | -9 | 271 | D | | | | | | | | | | | | | | |
12/17/25 17:53 | 12/15/25 | ARQT | Arcutis Biotherapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Burnett Patrick | CA | O | See Rema | M.d | 42 | 3.64 | 0 | 12 | 13 | 98 | D | | | | | | | | | | | | | | |
12/17/25 17:53 | 12/15/25 | ARQT | Arcutis Biotherapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Burnett Patrick | CA | O | See Rema | S.d | -333 | 28.94 | 0 | -12 | -10 | 98 | D | | | | | | | | | | | | | | |
12/17/25 17:43 | 12/16/25 | RPRX | Royalty Pharma Plc | X0 | Health | Drug | Pharmaceutical Preparations | Urist Marshall | NY | O | EVP,Rese | S | -766 | 38.32 | 0 | -20 | -11 | 166 | I | | | | | | | | | | | | | | |
12/17/25 17:39 | 12/15/25 | RPRX | Royalty Pharma Plc | X0 | Health | Drug | Pharmaceutical Preparations | Coyne Terrance P. | NY | O | EVP,CFO | S | -2,669 | 38.36 | 0 | -70 | -10 | 621 | I | | | | | | | | | | | | | | |
12/17/25 17:25 | 12/12/25 | HRMY | Harmony Biosciences Holdings, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Dayno Jeffrey M. | PA | DO | P,CEO | M.d | 164 | 8.22 | 0 | 20 | | 0 | D | | | | | | | | | | | | | | |
12/17/25 17:25 | 12/12/25 | HRMY | Harmony Biosciences Holdings, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Dayno Jeffrey M. | PA | DO | P,CEO | S.d | -1,040 | 40.11 | 0 | -26 | -100 | 0 | D | | | | | | | | | | | | | | |
12/17/25 16:58 | 12/15/25 | SPRB | Spruce Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Gharib Samir M. | CA | O | P,CFO | M.d | 0 | 0.00 | 0 | 1 | 14 | 8 | D | | | | | | | | | | | | | | |
12/17/25 16:56 | 12/15/25 | SPRB | Spruce Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Szwarcberg Javier B. | CA | DO | CEO | M.d | 0 | 0.00 | 0 | 3 | 23 | 14 | D | | | | | | | | | | | | | | |
12/17/25 16:47 | 12/15/25 | ONC | Beone Medicines Ltd. | | Health | Drug | Pharmaceutical Preparations | Oyler John | V8 | DO | CEO | S.m | -30,659 | 306.59 | 0 | -100 | 0 | 51,196 | D | | | | | | | | | | | | | | |
12/17/25 16:38 | 12/15/25 | KNSA | Kiniksa Pharmaceuticals International, Plc | | Health | Drug | Pharmaceutical Preparations | Quart Barry D | X0 | D | | M.d | 209 | 10.36 | 0 | 20 | | 13 | D | | | | | | | | | | | | | | |
12/17/25 16:38 | 12/15/25 | KNSA | Kiniksa Pharmaceuticals International, Plc | | Health | Drug | Pharmaceutical Preparations | Quart Barry D | X0 | D | | S.d | -836 | 41.51 | 0 | -20 | -62 | 13 | D | | | | | | | | | | | | | | |
12/17/25 16:37 | 12/15/25 | KNSA | Kiniksa Pharmaceuticals International, Plc | | Health | Drug | Pharmaceutical Preparations | Tessari Eben | X0 | O | COO | M.d | 53 | 8.83 | 0 | 6 | 56 | 17 | D | | | | | | | | | | | | | | |
12/17/25 16:37 | 12/15/25 | KNSA | Kiniksa Pharmaceuticals International, Plc | | Health | Drug | Pharmaceutical Preparations | Tessari Eben | X0 | O | COO | S.d | -501 | 41.56 | 0 | -12 | -42 | 17 | D | | | | | | | | | | | | | | |
12/17/25 16:23 | 12/15/25 | LFVN | Lifevantage Corp | | Health | Drug | Pharmaceutical Preparations | Lewis Darwin | UT | D | | P | 5 | 6.54 | 0 | 1 | 1 | 132 | D | | | | | | | | | | | | | | |
12/17/25 16:14 | 12/16/25 | RZLT | Rezolute, Inc. | NV | Health | Drug | Pharmaceutical Preparations | Hogenhuis Wladimir | CA | D | | P | 10 | 1.69 | 0 | 6 | 5 | 120 | D | | | | | | | | | | | | | | |
12/17/25 16:13 | 12/16/25 | RZLT | Rezolute, Inc. | NV | Health | Drug | Pharmaceutical Preparations | Roberts Brian Kenneth | CA | O | Chief Me | P | 48 | 1.70 | 0 | 28 | 9 | 324 | D | | | | | | | | | | | | | | |
12/17/25 16:10 | 12/15/25 | FULC | Fulcrum Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Oltmans Curtis Gale | MA | O | GC | S | -45 | 12.92 | 0 | -3 | -25 | 10 | D | | | | | | | | | | | | | | |
12/17/25 16:05 | 12/15/25 | VERA | Vera Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Turner William D. | CA | O | Chief Re | M.d | 155 | 15.53 | 0 | 10 | 80 | 23 | D | | | | | | | | | | | | | | |
12/17/25 16:05 | 12/15/25 | VERA | Vera Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Turner William D. | CA | O | Chief Re | S.d | -501 | 50.08 | 0 | -10 | -31 | 23 | D | | | | | | | | | | | | | | |
12/17/25 07:00 | 12/16/25 | RNXT | Renovorx, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Agah Ramtin | CA | DO | Chief Me | P | 10 | 0.8500 | 0 | 12 | 2 | 778 | D | | | | | | | | | | | | | | |
12/16/25 21:43 | 12/12/25 | IRON | Disc Medicine, Inc. | | Health | Drug | Pharmaceutical Preparations | Bitterman Kevin | MA | D | | S.dm | -16,859 | 91.56 | 0 | -184 | -93 | 14 | M | | | | | | | | | | | | | | |
12/16/25 21:43 | 12/15/25 | IRON | Disc Medicine, Inc. | | Health | Drug | Pharmaceutical Preparations | Bitterman Kevin | MA | D | | M.d | 95 | 13.50 | 0 | 7 | 98 | 14 | M | | | | | | | | | | | | | | |
12/16/25 21:31 | 12/15/25 | IRON | Disc Medicine, Inc. | | Health | Drug | Pharmaceutical Preparations | Savage William Jacob | MA | O | Chief Me | S | -1,194 | 91.22 | 0 | -13 | -15 | 76 | D | | | | | | | | | | | | | | |
12/16/25 20:50 | 12/12/25 | HROW | Harrow, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Boll Andrew R. | TN | O | P,CFO | M.d | 237 | 3.95 | 0 | 60 | 8 | 811 | D | | | | | | | | | | | | | | |
12/16/25 20:48 | 12/12/25 | HROW | Harrow, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Baum Mark L | TN | DO | CEO | M.d | 711 | 3.95 | 0 | 180 | 6 | 2,986 | D | | | | | | | | | | | | | | |
12/16/25 20:15 | 12/12/25 | MNKD | Mannkind Corp | DE | Health | Drug | Pharmaceutical Preparations | Castagna Michael | CT | DO | CEO | M.dm | 192 | 4.55 | 0 | 42 | 2 | 2,505 | D | | | | | | | | | | | | | | |
12/16/25 20:15 | 12/12/25 | MNKD | Mannkind Corp | DE | Health | Drug | Pharmaceutical Preparations | Castagna Michael | CT | DO | CEO | S.dm | -253 | 6.00 | 0 | -42 | -2 | 2,505 | D | | | | | | | | | | | | | | |
12/16/25 18:59 | 12/12/25 | SER | Serina Therapeutics, Inc. | AL | Health | Drug | Pharmaceutical Preparations | Moreadith Randall | AL | O | Chief Sc | M.d | 0 | 0.0600 | 0 | 2 | | 0 | D | | | | | | | | | | | | | | |
12/16/25 18:59 | 12/12/25 | SER | Serina Therapeutics, Inc. | AL | Health | Drug | Pharmaceutical Preparations | Moreadith Randall | AL | O | Chief Sc | S.d | -6 | 3.26 | 0 | -2 | -100 | 0 | D | | | | | | | | | | | | | | |
12/16/25 18:36 | 12/12/25 | LGND | Ligand Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Espinoza Octavio | FL | O | CFO | S | -340 | 188.31 | 0 | -2 | -6 | 26 | D | | | | | | | | | | | | | | |
12/16/25 18:34 | 12/15/25 | SILO | Silo Pharma, Inc. | NV | Health | Drug | Pharmaceutical Preparations | Weisblum Eric | FL | DO | CEO | P | 2 | 0.4150 | 0 | 5 | 2 | 217 | D | | | | | | | | | | | | | | |
12/16/25 18:27 | 12/12/25 | BBIO | Bridgebio Pharma, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kumar Neil | CA | DO | CEO | M.d | 0 | 0.00 | 0 | 61 | 1 | 5,543 | D | | | | | | | | | | | | | | |
12/16/25 18:27 | 12/15/25 | BBIO | Bridgebio Pharma, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kumar Neil | CA | DO | CEO | S.d | -2,240 | 74.64 | 0 | -30 | -1 | 5,543 | D | | | | | | | | | | | | | | |
12/16/25 18:00 | 12/12/25 | CLRB | Cellectar Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Neis John | NJ | D | | S | -1 | 3.70 | 0 | 0 | -95 | 0 | I | | | | | | | | | | | | | | |
12/16/25 17:41 | 12/15/25 | SXTP | 60 Degrees Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Dow Geoffrey S | DC | DO | P,CEO | P | 8 | 0.8024 | 0 | 10 | 19 | 60 | D | | | | | | | | | | | | | | |
12/16/25 17:09 | 12/15/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Edgemond James | MD | O | CFO,TREA | M.d | 514 | 146.03 | 0 | 4 | 76 | 8 | D | | | | | | | | | | | | | | |
12/16/25 17:09 | 12/15/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Edgemond James | MD | O | CFO,TREA | S.d | -1,742 | 495.36 | 0 | -4 | -30 | 8 | D | | | | | | | | | | | | | | |
12/16/25 17:08 | 12/15/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Rothblatt Martine A | MD | DO | CHAIRPER | M.dm | 962 | 120.26 | 0 | 8 | 1 | 639 | D | | | | | | | | | | | | | | |
12/16/25 17:08 | 12/15/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Rothblatt Martine A | MD | DO | CHAIRPER | S.dm | -3,953 | 494.09 | 0 | -8 | -1 | 639 | D | | | | | | | | | | | | | | |
12/16/25 17:07 | 12/15/25 | RAPP | Rapport Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Bredt David | MA | O | Chief Sc | S | -255 | 30.02 | 0 | -9 | -2 | 393 | D | | | | | | | | | | | | | | |
12/16/25 17:00 | 12/12/25 | CPRX | Catalyst Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Harper Molly | FL | D | | M.d | 116 | 5.78 | 0 | 20 | | 2 | D | | | | | | | | | | | | | | |
12/16/25 17:00 | 12/12/25 | CPRX | Catalyst Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Harper Molly | FL | D | | S.d | -622 | 23.25 | 0 | -27 | -92 | 2 | D | | | | | | | | | | | | | | |
12/16/25 16:52 | 12/15/25 | BCAX | Bicara Therapeutics Inc. | DE | Health | Drug | Pharmaceutical Preparations | Cohlhepp Ryan | MA | DO | P,COO | M.d | 30 | 3.79 | 0 | 8 | 4 | 189 | D | | | | | | | | | | | | | | |
12/16/25 16:52 | 12/15/25 | BCAX | Bicara Therapeutics Inc. | DE | Health | Drug | Pharmaceutical Preparations | Cohlhepp Ryan | MA | DO | P,COO | S.d | -234 | 18.68 | 0 | -13 | -6 | 189 | D | | | | | | | | | | | | | | |
12/16/25 16:42 | 12/12/25 | ELAN | Elanco Animal Health Inc | | Health | Drug | Pharmaceutical Preparations | Kurzius Lawrence Erik | IN | D | | P | 213 | 21.30 | 0 | 10 | 8 | 132 | D | | | | | | | | | | | | | | |
12/16/25 16:33 | 12/15/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Benkowitz Michael | MD | O | P,COO | M.d | 5,491 | 244.05 | 0 | 23 | | 3 | I | | | | | | | | | | | | | | |
12/16/25 16:33 | 12/15/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Benkowitz Michael | MD | O | P,COO | S.d | -11,167 | 496.30 | 0 | -23 | -89 | 3 | I | | | | | | | | | | | | | | |
12/16/25 16:30 | 12/15/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Patusky Christopher | MD | D | | M.d | 102 | 101.80 | 0 | 1 | 63 | 3 | D | | | | | | | | | | | | | | |
12/16/25 16:30 | 12/15/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Patusky Christopher | MD | D | | S.d | -496 | 495.95 | 0 | -1 | -28 | 3 | D | | | | | | | | | | | | | | |
12/16/25 16:30 | 12/12/25 | TYRA | Tyra Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Bensen Daniel | CA | O | Chief Di | S | -181 | 22.64 | 0 | -8 | -5 | 163 | D | | | | | | | | | | | | | | |
12/16/25 16:29 | 12/16/25 | CYTK | Cytokinetics Inc | | Health | Drug | Pharmaceutical Preparations | Malik Fady Ibraham | CA | O | EVP Rese | M.d | 23 | 10.60 | 0 | 2 | 2 | 139 | D | | | | | | | | | | | | | | |
12/16/25 16:29 | 12/16/25 | CYTK | Cytokinetics Inc | | Health | Drug | Pharmaceutical Preparations | Malik Fady Ibraham | CA | O | EVP Rese | S.d | -135 | 61.24 | 0 | -2 | -2 | 139 | D | | | | | | | | | | | | | | |
12/16/25 16:23 | 12/15/25 | TVTX | Travere Therapeutics, Inc. | CA | Health | Drug | Pharmaceutical Preparations | Calvin Sandra | CA | O | SVP,Chie | S | -105 | 36.00 | 0 | -3 | -6 | 46 | D | | | | | | | | | | | | | | |
12/16/25 16:22 | 12/12/25 | GALT | Galectin Therapeutics Inc | NV | Health | Drug | Pharmaceutical Preparations | Shlevin Harold H. | GA | D | | M.dm | 117 | 4.16 | 0 | 28 | 999% | 31 | D | | | | | | | | | | | | | | |
12/16/25 16:22 | 12/12/25 | GALT | Galectin Therapeutics Inc | NV | Health | Drug | Pharmaceutical Preparations | Shlevin Harold H. | GA | D | | S.dm | -177 | 6.28 | 0 | -28 | -48 | 31 | D | | | | | | | | | | | | | | |
12/16/25 16:16 | 12/12/25 | PGEN | Precigen, Inc. | VA | Health | Drug | Pharmaceutical Preparations | Kindler Jeffrey B | MD | D | | S | -856 | 3.63 | 0 | -235 | -68 | 111 | D | | | | | | | | | | | | | | |
12/16/25 16:05 | 12/12/25 | SLGL | Sol-Gel Technologies Ltd. | L3 | Health | Drug | Pharmaceutical Preparations | Opaleye Management Inc. | MA | T | | P | 3 | 40.00 | 0 | 0 | 0 | 382 | I | | | | | | | | | | | | | | |
12/16/25 14:59 | 12/12/25 | NATR | Natures Sunshine Products Inc | UT | Health | Drug | Pharmaceutical Preparations | Yates Bryant J | UT | O | EVP,P,Eu | S | -38 | 22.29 | 0 | -2 | -2 | 99 | D | | | | | | | | | | | | | | |
12/16/25 13:14 | 12/15/25 | ARWR | Arrowhead Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Anzalone Christopher Richard | CA | DO | CEO | S.m | -12,349 | 67.00 | 0 | -184 | -4 | 3,917 | D | | | | | | | | | | | | | | |
12/16/25 09:30 | 12/15/25 | RLMD | Relmada Therapeutics, Inc. | NV | Health | Drug | Pharmaceutical Preparations | Traversa Sergio | FL | DO | CEO | P.d | 113 | 4.12 | 0 | 28 | 2 | 1,300 | D | | | | | | | | | | | | | | |
12/16/25 09:30 | 12/15/25 | RLMD | Relmada Therapeutics, Inc. | NV | Health | Drug | Pharmaceutical Preparations | Shenouda Maged | FL | O | CFO | P.d | 48 | 4.12 | 0 | 12 | 1 | 800 | D | | | | | | | | | | | | | | |
12/16/25 08:56 | 12/15/25 | ANIX | Anixa Biosciences Inc | DE | Health | Drug | Pharmaceutical Preparations | Titterton Lewis H Jr | CA | D | | M.d | 47 | 2.92 | 0 | 16 | 2 | 969 | D | | | | | | | | | | | | | | |
12/15/25 21:34 | 12/11/25 | ROIV | Roivant Sciences Ltd. | D0 | Health | Drug | Pharmaceutical Preparations | Ramaswamy Vivek | DC | T | | M.dm | 93,513 | 12.68 | 0 | 7,375 | 19 | 47,012 | D | | | | | | | | | | | | | | |
12/15/25 21:34 | 12/11/25 | ROIV | Roivant Sciences Ltd. | D0 | Health | Drug | Pharmaceutical Preparations | Ramaswamy Vivek | DC | T | | S.dm | -67,942 | 21.89 | 0 | -3,104 | -6 | 47,012 | D | | | | | | | | | | | | | | |
12/15/25 20:07 | 12/11/25 | VERA | Vera Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Enright Patrick G | CA | D | | P | 250 | 42.50 | 0 | 6 | 0 | 5,400 | D | | | | | | | | | | | | | | |
12/15/25 20:02 | 12/14/25 | BTAI | Bioxcel Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Mehta Vimal | CT | DO | CEO,P | M.dm | 0 | 0.00 | 0 | 0 | 0 | 501 | D | | | | | | | | | | | | | | |
12/15/25 20:01 | 12/14/25 | BTAI | Bioxcel Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Steinhart Richard I | CT | O | CFO | M.dm | 0 | 0.00 | 0 | 0 | 1 | 7 | D | | | | | | | | | | | | | | |
12/15/25 20:01 | 12/14/25 | BTAI | Bioxcel Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Rodriguez Javier | CT | O | See Rema | M.dm | 0 | 0.00 | 0 | 0 | 1 | 7 | D | | | | | | | | | | | | | | |
12/15/25 20:00 | 12/14/25 | BTAI | Bioxcel Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Yocca Frank | CT | O | Chief Sc | M.dm | 0 | 0.00 | 0 | 0 | 1 | 6 | D | | | | | | | | | | | | | | |
12/15/25 19:55 | 12/11/25 | CLYM | Climb Bio, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Ra Capital Management, L.P. | MA | DT | | P.dm | 755 | 2.40 | 0 | 315 | 3 | 11,294 | I | | | | | | | | | | | | | | |
12/15/25 19:35 | 12/15/25 | RZLT | Rezolute, Inc. | NV | Health | Drug | Pharmaceutical Preparations | Evans Daron | CA | O | CFO | P | 80 | 1.77 | 0 | 45 | 10 | 513 | M | | | | | | | | | | | | | | |
12/15/25 19:35 | 12/15/25 | RZLT | Rezolute, Inc. | NV | Health | Drug | Pharmaceutical Preparations | Elam Nevan C | CA | DO | CEO | P | 51 | 1.59 | 0 | 32 | 5 | 641 | D | | | | | | | | | | | | | | |
12/15/25 19:34 | 12/15/25 | RZLT | Rezolute, Inc. | NV | Health | Drug | Pharmaceutical Preparations | Karnawat Sunil Ratilal | CA | O | Chief Co | P | 20 | 1.62 | 0 | 12 | 17 | 81 | D | | | | | | | | | | | | | | |
12/15/25 17:49 | 12/11/25 | IRON | Disc Medicine, Inc. | | Health | Drug | Pharmaceutical Preparations | Quisel John D | MA | DO | CEO | M.d | 394 | 9.86 | 0 | 40 | 30 | 172 | D | | | | | | | | | | | | | | |
12/15/25 17:49 | 12/11/25 | IRON | Disc Medicine, Inc. | | Health | Drug | Pharmaceutical Preparations | Quisel John D | MA | DO | CEO | S.d | -3,722 | 93.05 | 0 | -40 | -19 | 172 | D | | | | | | | | | | | | | | |
12/15/25 17:39 | 12/12/25 | EQ | Equillium, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Zedelmayer Christine | CA | O | SVP,COO | S.m | -47 | 1.33 | 0 | -36 | -28 | 91 | D | | | | | | | | | | | | | | |
12/15/25 17:24 | 12/12/25 | XERS | Xeris Biopharma Holdings, Inc. | | Health | Drug | Pharmaceutical Preparations | Bormann-Kennedy Barbara-Jean Anne | IL | D | | S | -106 | 7.09 | 0 | -15 | -10 | 143 | D | | | | | | | | | | | | | | |
12/15/25 17:24 | 12/15/25 | ZNTL | Zentalis Pharmaceuticals, Inc. | | Health | Drug | Pharmaceutical Preparations | Matrix Capital Management Company, LP | MA | T | | S | -9,975 | 1.33 | 0 | -7,500 | -54 | 6,460 | I | | | | | | | | | | | | | | |
12/15/25 17:17 | 12/11/25 | AMPH | Amphastar Pharmaceuticals, Inc. | | Health | Drug | Pharmaceutical Preparations | Petersen Floyd F. | CA | D | | S.m | -108 | 25.82 | 0 | -4 | -6 | 71 | D | | | | | | | | | | | | | | |
12/15/25 16:51 | 12/11/25 | PAHC | Phibro Animal Health Corp | DE | Health | Drug | Pharmaceutical Preparations | Bendheim Jack | NJ | DOT | P,CEO | S | -235 | 40.93 | 0 | -6 | -9 | 56 | I | | | | | | | | | | | | | | |
12/15/25 16:43 | 12/11/25 | ELAN | Elanco Animal Health Inc | | Health | Drug | Pharmaceutical Preparations | Modi Rajeev A. | IN | O | SEE REMA | P | 96 | 21.33 | 0 | 5 | 4 | 123 | D | | | | | | | | | | | | | | |
12/15/25 16:42 | 12/11/25 | ELAN | Elanco Animal Health Inc | | Health | Drug | Pharmaceutical Preparations | Vanhimbergen Robert M | IN | O | EVP,CFO | P | 150 | 21.64 | 0 | 7 | 6 | 124 | D | | | | | | | | | | | | | | |
12/15/25 16:41 | 12/11/25 | ELAN | Elanco Animal Health Inc | | Health | Drug | Pharmaceutical Preparations | Simmons Jeffrey N | IN | DO | P,CEO,Di | P | 478 | 21.75 | 0 | 22 | 1 | 1,969 | I | | | | | | | | | | | | | | |
12/15/25 16:38 | 12/12/25 | OGEN | Oragenics Inc | FL | Health | Drug | Pharmaceutical Preparations | Telling Fred | FL | D | | S.d | 0 | 0.9446 | 0 | 0 | -1 | 35 | D | | | | | | | | | | | | | | |
12/15/25 16:32 | 12/11/25 | WVE | Wave Life Sciences Ltd. | X0 | Health | Drug | Pharmaceutical Preparations | Gsk Plc | X0 | T | | P | 27,930 | 19.00 | 0 | 1,470 | 9 | 18,246 | I | | | | | | | | | | | | | | |
12/15/25 16:30 | 12/11/25 | RYTM | Rhythm Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Cramer Pamela J. | MA | O | CHRO | M.d | 92 | 27.35 | 0 | 3 | 19 | 21 | D | | | | | | | | | | | | | | |
12/15/25 16:30 | 12/11/25 | RYTM | Rhythm Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Cramer Pamela J. | MA | O | CHRO | S.d | -372 | 111.00 | 0 | -3 | -14 | 21 | D | | | | | | | | | | | | | | |
12/15/25 16:18 | 12/11/25 | CRBP | Corbus Pharmaceuticals Holdings, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Cormorant Asset Management, LP | MA | T | | S | -344 | 11.46 | 0 | -30 | -1 | 2,345 | I | | | | | | | | | | | | | | |
12/15/25 16:15 | 12/11/25 | BMEA | Biomea Fusion, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Erdtmann Rainer M | CA | DO | See Rema | P | 43 | 1.43 | 0 | 30 | 1 | 2,573 | D | | | | | | | | | | | | | | |
12/12/25 20:30 | 12/11/25 | AARD | Aardvark Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Sun Nelson | CA | O | CFO | P | 43 | 14.40 | 0 | 3 | 3 | 108 | D | | | | | | | | | | | | | | |
12/12/25 20:30 | 12/11/25 | AARD | Aardvark Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Lee Tien-Li | CA | DOT | CEO | P | 101 | 14.49 | 0 | 7 | 0 | 3,026 | D | | | | | | | | | | | | | | |
12/12/25 19:05 | 12/10/25 | SPRB | Spruce Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Gharib Samir M. | CA | O | P,CFO | M.dm | 0 | 0.00 | 0 | 2 | 46 | 8 | D | | | | | | | | | | | | | | |
12/12/25 19:03 | 12/10/25 | SPRB | Spruce Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Szwarcberg Javier B. | CA | DO | CEO | M.dm | 0 | 0.00 | 0 | 6 | 90 | 13 | D | | | | | | | | | | | | | | |
12/12/25 18:00 | 12/12/25 | TTRX | Turn Therapeutics Inc. | DE | Health | Drug | Pharmaceutical Preparations | Chaudhary Zuraiz | CA | O | See Rema | P | 9 | 3.50 | 0 | 3 | 25 | 13 | D | | | | | | | | | | | | | | |
12/12/25 17:32 | 12/10/25 | HOWL | Werewolf Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Evnin Luke | MA | D | | S.m | -89 | 1.07 | 0 | -83 | -3 | 2,890 | I | | | | | | | | | | | | | | |
12/12/25 17:30 | 12/10/25 | CYRX | Cryoport, Inc. | NV | Health | Drug | Pharmaceutical Preparations | Mandalam Ramkumar | TN | D | | S | -116 | 9.99 | 0 | -12 | -13 | 81 | D | | | | | | | | | | | | | | |
12/12/25 17:17 | 12/12/25 | IMVT | Immunovant, Inc. | D0 | Health | Drug | Pharmaceutical Preparations | Roivant Sciences Ltd. | X0 | DT | | P | 350,000 | 21.00 | 0 | 16,667 | 17 | 113,317 | D | | | | | | | | | | | | | | |