Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	Title	T	TVal	Price	Qty	oc	Own	H
1/28/26 18:30	12/15/25	MIST	Milestone Pharmaceuticals Inc.	A8	Health	Drug	Pharmaceutical Preparations	Bharucha David	A8	O	Chief Me	S.dm	-158	2.25	-70	-38	113	D
1/28/26 18:30	1/26/26	MIST	Milestone Pharmaceuticals Inc.	A8	Health	Drug	Pharmaceutical Preparations	Bharucha David	A8	O	Chief Me	M.d	0	0.00	20	22	113	D
1/28/26 18:30	12/15/25	MIST	Milestone Pharmaceuticals Inc.	A8	Health	Drug	Pharmaceutical Preparations	Nelson Jeffrey Edward	A8	O	COO	S.dm	-158	2.25	-70	-58	50	D
1/28/26 18:30	1/26/26	MIST	Milestone Pharmaceuticals Inc.	A8	Health	Drug	Pharmaceutical Preparations	Nelson Jeffrey Edward	A8	O	COO	M.d	0	0.00	20	68	50	D
1/28/26 18:30	12/15/25	MIST	Milestone Pharmaceuticals Inc.	A8	Health	Drug	Pharmaceutical Preparations	Muller Lorenz	A8	O	Chief Co	S.dm	-146	2.25	-65	-24	205	D
1/28/26 18:30	1/26/26	MIST	Milestone Pharmaceuticals Inc.	A8	Health	Drug	Pharmaceutical Preparations	Muller Lorenz	A8	O	Chief Co	M.d	0	0.00	20	11	205	D
1/28/26 18:30	12/15/25	MIST	Milestone Pharmaceuticals Inc.	A8	Health	Drug	Pharmaceutical Preparations	Hasija Amit	A8	O	CFO,EVP	S.dm	-158	2.25	-70	-41	100	D
1/28/26 18:30	1/26/26	MIST	Milestone Pharmaceuticals Inc.	A8	Health	Drug	Pharmaceutical Preparations	Hasija Amit	A8	O	CFO,EVP	M.d	0	0.00	20	25	100	D
1/28/26 18:30	12/15/25	MIST	Milestone Pharmaceuticals Inc.	A8	Health	Drug	Pharmaceutical Preparations	Oliveto Joseph	A8	DO	P,CEO	S.dm	-375	2.24	-168	-26	483	D
1/28/26 18:30	1/26/26	MIST	Milestone Pharmaceuticals Inc.	A8	Health	Drug	Pharmaceutical Preparations	Oliveto Joseph	A8	DO	P,CEO	M.d	0	0.00	67	16	483	D
1/28/26 18:07	1/26/26	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	Duato Joaquin	NJ	DO	CEO,CB	S	-22,123	221.23	-100	-25	308	I
1/28/26 17:01	1/26/26	CLNN	Clene Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ugwumba Chidozie	AR	T		S.m	-96	4.98	-19	-3	580	I
1/28/26 16:31	1/20/26	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Benkowitz Michael	MD	O	P,COO	M.dm	4,022	132.42	30		3	I
1/28/26 16:31	1/20/26	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Benkowitz Michael	MD	O	P,COO	S.dm	-14,277	470.03	-30	-92	3	I
1/28/26 16:30	1/26/26	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Boyle Dana	NC	O	Chief Ac	S	-66	41.65	-2	-1	179	D
1/28/26 16:30	1/20/26	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Benkowitz Michael	MD	O	P,COO	M.d	1,722	117.76	15		3	I
1/28/26 16:30	1/20/26	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Benkowitz Michael	MD	O	P,COO	S.d	-6,796	464.66	-15	-85	3	I
1/28/26 16:30	1/26/26	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Adair Jason	NC	O	Chief Bu	S	-29	41.65	-1	0	211	D
1/28/26 16:05	1/27/26	SIGA	Siga Technologies Inc	DE	Health	Drug	Pharmaceutical Preparations	Nguyen Diem	NY	DO	CEO	M.d	0	0.00	56	125	101	D
1/27/26 21:35	1/27/26	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Powl Brian T.	CA	O	Chief Co	S	-54	8.46	-6	-3	183	D
1/27/26 21:35	1/27/26	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ford Kathleen	CA	O	COO	S	-15	8.46	-2	-1	154	D
1/27/26 21:35	1/27/26	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Leoni Mollie	CA	O	Chief Me	S	-69	8.46	-8	-3	267	D
1/27/26 21:35	1/27/26	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Doyle Thomas James	CA	O	SVP,Fina	S	-60	8.46	-7	-5	146	D
1/27/26 21:35	1/27/26	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Burrows Francis	CA	O	Chief Sc	S	-11	8.46	-1	-4	32	D
1/27/26 21:35	1/27/26	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bair Teresa Brophy	CA	O	GC	S	-95	8.46	-11	-5	227	D
1/27/26 21:21	1/23/26	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	Patel Dinesh V Ph D	CA	DO	P,CEO	M.dm	521	10.79	48	9	575	D
1/27/26 21:21	1/23/26	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	Patel Dinesh V Ph D	CA	DO	P,CEO	S.dm	-4,064	84.18	-48	-8	575	D
1/27/26 21:20	1/27/26	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	Ali Asif	CA	O	CFO	M.d	453	16.18	28	87	60	D
1/27/26 21:20	1/27/26	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	Ali Asif	CA	O	CFO	S.d	-3,841	83.13	-46	-43	60	D
1/27/26 21:19	1/23/26	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	Molina Arturo Md	CA	O	Chief Me	S.dm	-1,905	82.30	-23	-22	84	D
1/27/26 21:19	1/26/26	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	Molina Arturo Md	CA	O	Chief Me	M.dm	80	8.04	10	13	84	D
1/27/26 20:25	1/23/26	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	Dube Eric M	CA	DO	CEO	M.dm	928	15.46	60	17	419	D
1/27/26 20:25	1/23/26	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	Dube Eric M	CA	DO	CEO	S.dm	-1,805	30.09	-60	-13	419	D
1/27/26 17:38	1/23/26	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	Kooij Louise Frederika	P7	O	Chief Ac	M.dm	791	10.90	73		24	D
1/27/26 17:38	1/23/26	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	Kooij Louise Frederika	P7	O	Chief Ac	S.dm	-2,416	33.29	-73	-75	24	D
1/27/26 16:30	1/23/26	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bjerkholt Eric	CA	O	CFO	M.d	0	0.00	3	6	44	D
1/27/26 16:30	1/26/26	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bjerkholt Eric	CA	O	CFO	S.d	-101	96.19	-1	-2	44	D
1/27/26 16:30	1/23/26	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Radovich Peter	CA	O	P,COO	M.d	0	0.00	6	33	23	D
1/27/26 16:30	1/26/26	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Radovich Peter	CA	O	P,COO	S.d	-302	96.19	-3	-12	23	D
1/27/26 16:30	1/23/26	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Howe Jolanda	CA	O	SVP,GLOB	M.d	0	0.00	2	68	4	D
1/27/26 16:30	1/26/26	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Howe Jolanda	CA	O	SVP,GLOB	S.d	-81	96.19	-1	-19	4	D
1/27/26 16:30	1/23/26	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Peetz Christopher	CA	DO	CEO	M.d	0	0.00	13	4	357	D
1/27/26 16:30	1/26/26	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Peetz Christopher	CA	DO	CEO	S.d	-657	96.19	-7	-2	357	D
1/27/26 16:15	1/23/26	PAHC	Phibro Animal Health Corp	DE	Health	Drug	Pharmaceutical Preparations	Bendheim Jack	NJ	DOT	P,CEO	S.d	-50	40.55	-1	-2	62	I
1/27/26 16:14	1/23/26	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Heron Patrick J	CA	D		P	9,000	68.48	131	3	4,032	I
1/27/26 07:10	1/25/26	ALT	Altimmune, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jordt Raymond M	MD	O	Chief Bu	M.d	0	0.00	15	37	54	D
1/27/26 07:05	1/25/26	ALT	Altimmune, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Garg Vipin K	MD	D		M.d	0	0.00	42	12	379	D
1/27/26 07:00	1/25/26	ALT	Altimmune, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Roberts M Scot	MD	O	Chief Sc	M.d	0	0.00	15	21	84	D
1/26/26 18:02	1/26/26	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Levy Richard S	PA	D		M.d	66	16.46	4	19	25	D
1/26/26 17:38	1/26/26	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Huntsman Carole	PA	O	Chief Co	S	-449	493.78	-1	-9	9	D
1/26/26 17:24	1/22/26	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tpg Gp A, LLC	TX	T		S	-10,000	40.00	-250	-4	6,495	I
1/26/26 17:14	1/26/26	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sibold William John	PA	DO	P,CEO	S	-777	492.42	-2	-1	148	D
1/26/26 17:05	1/26/26	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Taub Rebecca	PA	D		S	-319	492.42	-1	0	1,108	D
1/26/26 16:49	1/24/26	HRMY	Harmony Biosciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kapadia Sandip	PA	O	CFO	M.dm	0	0.00	9		2	D
1/26/26 16:48	1/24/26	HRMY	Harmony Biosciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Serafin Andrew	PA	O	CHIEF ST	M.dm	0	0.00	5		1	D
1/26/26 16:45	1/24/26	HRMY	Harmony Biosciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Budur Kumar	PA	O	CHIEF ME	M.dm	0	0.00	5		1	D
1/26/26 16:43	1/24/26	HRMY	Harmony Biosciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dayno Jeffrey M.	PA	DO	P,CEO	M.dm	0	0.00	24		7	D
1/26/26 16:35	1/22/26	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Vasanthavada Madhav	OH	O	Chief Co	S	-67	5.29	-13	-4	319	D
1/26/26 16:34	1/22/26	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cohlhepp Ryan	MA	DO	P,COO	S	-69	18.10	-4	-2	210	D
1/26/26 16:33	1/22/26	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hyep Ivan	MA	O	CFO	M.d	7	3.79	2	1	145	D
1/26/26 16:33	1/22/26	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hyep Ivan	MA	O	CFO	S.d	-34	18.15	-2	-1	145	D
1/26/26 16:10	1/23/26	RPRX	Royalty Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Urist Marshall	NY	O	EVP,Rese	S	-805	40.26	-20	-30	46	I
1/26/26 16:01	1/23/26	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	Desjarlais John R	CA	O	SVP,CSO	M.d	67	12.51	5	2	248	D
1/26/26 08:02	1/23/26	ABT	Abbott Laboratories	IL	Health	Drug	Pharmaceutical Preparations	Ford Robert B	IL	DO	CB,CEO	P	2,014	107.13	19	4	470	I
1/23/26 19:00	1/22/26	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pizzie Nick	NY	O	CFO	M.d	42	3.50	12	39	43	D
1/23/26 19:00	1/22/26	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pizzie Nick	NY	O	CFO	S.d	-2,255	187.92	-12	-22	43	D
1/23/26 19:00	1/21/26	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Maizel Ari	NY	O	Chief Co	M.d	530	70.73	8		0	D
1/23/26 19:00	1/21/26	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Maizel Ari	NY	O	Chief Co	S.d	-1,383	184.44	-8	-100	0	D
1/23/26 17:51	1/22/26	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Devers Shannon L.	CA	O	EVP,Chie	S	-323	81.34	-4	-15	23	D
1/23/26 17:42	1/22/26	SLGL	Sol-Gel Technologies Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T		P.m	187	56.36	3	1	460	I
1/23/26 17:34	1/21/26	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hughes Steven George	CA	O	Chief Me	S	-355	72.45	-5	-13	32	D
1/23/26 17:34	1/21/26	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Boyce Sarah	CA	DO	P,CEO	S	-1,042	72.45	-14	-5	269	D
1/23/26 17:33	1/21/26	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Flanagan W. Michael	CA	O	Chief Sc	S	-473	72.45	-7	-7	85	D
1/23/26 17:33	1/21/26	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Maclean Michael F	CA	O	CFO	S	-329	72.45	-5	-7	59	D
1/23/26 17:33	1/21/26	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Levin Arthur A	CA	D		S	-127	72.45	-2	-1	170	D
1/23/26 17:33	1/21/26	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McCarthy Teresa	CA	O	CHRO	S	-212	72.45	-3	-3	114	D
1/23/26 17:33	1/22/26	CLNN	Clene Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ugwumba Chidozie	AR	T		S.m	-97	5.30	-18	-3	600	I
1/23/26 17:30	1/21/26	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Howe Jolanda	CA	O	SVP,GLOB	M.d	0	0.00	2	103	3	D
1/23/26 17:30	1/22/26	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Howe Jolanda	CA	O	SVP,GLOB	S.d	-86	93.33	-1	-23	3	D
1/23/26 17:30	1/21/26	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Quan Joanne	CA	O	CHIEF ME	M.d	0	0.00	3	35	13	D
1/23/26 17:30	1/22/26	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Quan Joanne	CA	O	CHIEF ME	S.d	-170	93.33	-2	-12	13	D
1/23/26 17:30	1/21/26	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bjerkholt Eric	CA	O	CFO	M.d	0	0.00	3	9	42	D
1/23/26 17:30	1/22/26	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bjerkholt Eric	CA	O	CFO	S.d	-133	93.33	-1	-3	42	D
1/23/26 17:30	1/21/26	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Radovich Peter	CA	O	P,COO	M.d	0	0.00	4	25	21	D
1/23/26 17:30	1/22/26	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Radovich Peter	CA	O	P,COO	S.d	-222	93.33	-2	-10	21	D
1/23/26 17:30	1/21/26	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Peetz Christopher	CA	DO	CEO	M.d	0	0.00	13	4	351	D
1/23/26 17:30	1/22/26	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Peetz Christopher	CA	DO	CEO	S.d	-662	93.33	-7	-2	351	D
1/23/26 16:48	1/20/26	RPRX	Royalty Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Coyne Terrance P.	NY	O	EVP,CFO	S	-2,738	39.35	-70	-13	481	I
1/23/26 16:31	1/21/26	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Miller Deborah Ann	MA	O	GC	M.dm	418	27.85	15	34	60	D
1/23/26 16:31	1/21/26	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Miller Deborah Ann	MA	O	GC	S.dm	-1,652	110.15	-15	-20	60	D
1/23/26 16:13	1/22/26	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Baumal Caroline	MA	O	Chief Me	S	-61	21.77	-3	-3	87	D
1/23/26 16:12	1/22/26	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chopas James George	MA	O	VP,Chief	S	-45	21.77	-2	-4	50	D
1/23/26 16:11	1/22/26	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Delong Mark Jeffrey	MA	O	Chief Bu	S	-73	21.77	-3	-4	78	D
1/23/26 16:10	1/22/26	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Deschatelets Pascal	MA	O	Chief Sc	S	-129	21.77	-6	-1	1,151	D
1/23/26 16:09	1/22/26	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Francois Cedric	MA	DO	CEO	S	-592	21.77	-27	-2	1,600	D
1/23/26 16:08	1/22/26	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Nicholson Nur	MA	O	Chief Te	S	-168	21.77	-8	-10	71	D
1/23/26 16:07	1/22/26	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sullivan Timothy Eugene	MA	O	CFO	S	-224	21.77	-10	-6	154	D
1/23/26 16:05	1/22/26	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Watson David O.	MA	O	GC	S	-170	21.77	-8	-5	149	D
1/23/26 16:05	1/21/26	PVLA	Palvella Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Goin Kathleen	PA	O	COO	M.d	35	8.11	4		0	D
1/23/26 16:05	1/21/26	PVLA	Palvella Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Goin Kathleen	PA	O	COO	S.d	-420	97.63	-4	-100	0	D
1/23/26 13:34	1/21/26	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Edris Badreddin	CO	D		M.d	170	1.47	115		20	D
1/23/26 13:34	1/21/26	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Edris Badreddin	CO	D		S.d	-3,399	29.44	-115	-85	20	D
1/23/26 12:35	1/22/26	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	Moreadith Randall	AL	O	Chief Sc	M.d	0	0.0600	3		0	D
1/23/26 12:35	1/22/26	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	Moreadith Randall	AL	O	Chief Sc	S.d	-7	2.95	-3	-100	0	D
1/22/26 21:46	1/20/26	PLRX	Pliant Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cummings Keith Lamont	CA	O	CFO	S	-31	1.28	-24	-7	297	D
1/22/26 21:38	1/20/26	PLRX	Pliant Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cheung Lily	CA	O	Chief Hu	S	-10	1.28	-8	-14	45	D
1/22/26 21:38	1/20/26	PLRX	Pliant Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Coulie Bernard	CA	DO	P,CEO	S	-114	1.28	-89	-9	915	D
1/22/26 21:38	1/20/26	PLRX	Pliant Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kuo Minnie	CA	O	COO	S	-9	1.28	-7	-15	38	D
1/22/26 21:30	1/21/26	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dillione Janet	NJ	D		S	-69	6.88	-10	-21	38	D
1/22/26 20:34	1/22/26	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Vazzano Joseph Walter	OH	O	CFO	S	-100	5.33	-19	-3	569	D
1/22/26 20:33	1/22/26	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Seshadri Vishwas	OH	DO	CEO	S	-372	5.33	-70	-5	1,460	D
1/22/26 20:33	1/22/26	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	O'Malley Brendan M.	OH	O	SVP,GC	S	-72	5.33	-14	-3	451	D
1/22/26 20:09	1/22/26	COGT	Cogent Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fairmount Funds Management LLC	PA	D		S.d	-127,400	36.40	-3,500	-39	5,503	I
1/22/26 19:41	1/21/26	PAHC	Phibro Animal Health Corp	DE	Health	Drug	Pharmaceutical Preparations	Bendheim Jack	NJ	DOT	P,CEO	S.m	-1,165	41.82	-28	-45	34	I
1/22/26 19:31	1/20/26	NKTR	Nektar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	Zalevsky Jonathan	CA	O	Chief R,	S	-138	35.67	-4	-15	21	D
1/22/26 19:26	1/20/26	FOLD	Amicus Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Campbell Bradley L	NJ	DO	P,CEO	M.d	458	6.10	75	8	1,021	D
1/22/26 19:26	1/20/26	FOLD	Amicus Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Campbell Bradley L	NJ	DO	P,CEO	S.d	-1,073	14.31	-75	-7	1,021	D
1/22/26 19:00	1/20/26	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ceesay Abraham	MA	DO	CEO	S	-285	26.12	-11	-2	670	M
1/22/26 17:34	1/20/26	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lyssikatos Joseph P	CO	O	CHIEF SC	S	-535	26.75	-20	-3	745	I
1/22/26 17:33	1/20/26	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Heyman Richard A.	CO	D		S	-33	26.75	-1	-1	173	I
1/22/26 17:24	1/20/26	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	Somaiya Mayur Ian	P7	O	CFO	M.dm	926	9.26	100		58	D
1/22/26 17:24	1/20/26	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	Somaiya Mayur Ian	P7	O	CFO	S.dm	-3,261	32.61	-100	-63	58	D
1/22/26 16:28	1/20/26	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Lewis William	NJ	DO	Chair,CE	M.d	267	24.94	11	2	591	D
1/22/26 16:28	1/20/26	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Lewis William	NJ	DO	Chair,CE	S.d	-1,700	158.93	-11	-2	591	D
1/22/26 16:09	1/21/26	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Abate Kristin	MA	O	Chief Ac	S	-2	5.96	0	-1	23	D
1/22/26 13:04	12/12/25	OGEN	Oragenics Inc	FL	Health	Drug	Pharmaceutical Preparations	Telling Fred	FL	D		S.ad	0	0.9446	0	-18	1	D
1/22/26 07:00	1/21/26	RNXT	Renovorx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Agah Ramtin	CA	DO	Chief Me	P	10	0.9975	10	1	798	D
1/21/26 21:00	1/20/26	OLMA	Olema Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Harmon Cyrus	CA	D		S	-269	26.88	-10	-1	845	D
1/21/26 19:17	1/20/26	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	Moreadith Randall	AL	O	Chief Sc	M.dm	0	0.0600	4		0	D
1/21/26 19:17	1/20/26	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	Moreadith Randall	AL	O	Chief Sc	S.dm	-12	3.04	-4	-100	0	D
1/21/26 18:55	1/20/26	IRON	Disc Medicine, Inc.		Health	Drug	Pharmaceutical Preparations	Khara Rahul	MA	O	GC	M.d	14	13.50	1	3	38	D
1/21/26 18:55	1/20/26	IRON	Disc Medicine, Inc.		Health	Drug	Pharmaceutical Preparations	Khara Rahul	MA	O	GC	S.d	-70	69.74	-1	-3	38	D
1/21/26 18:13	1/16/26	CLNN	Clene Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ugwumba Chidozie	AR	T		S.m	-162	4.97	-32	-5	618	I
1/21/26 17:17	1/20/26	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	Molina Arturo Md	CA	O	Chief Me	S	-785	82.48	-10	-9	97	D
1/21/26 17:17	1/20/26	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Looker Benjamin	MI	O	GC	S	-5	2.88	-2	0	384	D
1/21/26 17:16	1/20/26	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	Patel Dinesh V Ph D	CA	DO	P,CEO	S	-2,840	82.48	-34	-6	581	D
1/21/26 17:15	1/20/26	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	Ali Asif	CA	O	CFO	S	-708	82.48	-9	-10	78	D
1/21/26 16:30	1/21/26	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Alvino Mark	OH	D		S	-71	5.23	-14	-22	49	D
1/21/26 16:20	1/16/26	BIOA	Bioage Labs, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Goldstein Dov A Md	CA	O	CFO	M.d	16	4.38	4	16	26	D
1/21/26 16:19	1/20/26	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Baumal Caroline	MA	O	Chief Me	S	-37	19.79	-2	-2	89	D
1/21/26 16:18	1/20/26	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chopas James George	MA	O	VP,Chief	S	-14	19.79	-1	-1	52	D
1/21/26 16:17	1/20/26	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Delong Mark Jeffrey	MA	O	Chief Bu	S	-26	19.79	-1	-2	82	D
1/21/26 16:16	1/20/26	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Deschatelets Pascal	MA	O	Chief Sc	S	-18	19.79	-1	0	1,157	D
1/21/26 16:14	1/20/26	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Francois Cedric	MA	DO	CEO	S	-162	19.79	-8	-1	1,628	D
1/21/26 16:12	1/20/26	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Nicholson Nur	MA	O	Chief Te	S	-44	19.79	-2	-3	79	D
1/21/26 16:10	1/20/26	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sullivan Timothy Eugene	MA	O	CFO	S	-57	19.79	-3	-2	165	D
1/21/26 16:08	1/20/26	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Watson David O.	MA	O	GC	S	-49	19.79	-2	-2	156	D
1/21/26 16:05	1/20/26	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	Reed Elizabeth E	CA	O	GC,GC	M.d	191	19.08	10	12	90	D
1/21/26 16:05	1/20/26	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	Reed Elizabeth E	CA	O	GC,GC	S.d	-273	27.34	-10	-10	90	D
1/21/26 16:05	1/16/26	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Quan Joanne	CA	O	CHIEF ME	M.d	0	0.00	13		11	D
1/21/26 16:05	1/20/26	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Quan Joanne	CA	O	CHIEF ME	S.d	-624	90.27	-7	-38	11	D
1/21/26 16:04	12/11/25	SPRB	Spruce Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ways Douglas Kirk	CA	DO	Interim	M.d	0	0.00	1	New	1	D
1/21/26 12:46	1/21/26	XCUR	Exicure, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Exicure Hitron Inc.	MA	T		S	-1,163	4.50	-258	-14	1,599	D
1/21/26 09:09	1/16/26	IMRX	Immuneering Corp	DE	Health	Drug	Pharmaceutical Preparations	Brakewood Harold Eugene	MA	O	Chief Bu	P	25	4.76	5	91	11	D
1/20/26 21:46	1/15/26	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cohen Joshua B	MA	DO	Co-CEO	M.dm	1,514	7.57	200	6	3,379	D
1/20/26 21:46	1/15/26	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cohen Joshua B	MA	DO	Co-CEO	S.dm	-1,878	13.59	-138	-4	3,379	D
1/20/26 21:46	1/15/26	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Klee Justin B.	MA	DO	Co-CEO	M.dm	1,514	7.57	200	6	3,379	D
1/20/26 21:46	1/15/26	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Klee Justin B.	MA	DO	Co-CEO	S.dm	-1,878	13.59	-138	-4	3,379	D
1/20/26 20:39	1/15/26	HRMY	Harmony Biosciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kapadia Sandip	PA	O	CFO	S	-753	35.92	-21	-100	0	D
1/20/26 20:33	1/20/26	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rodman David Malcom	PA	O	Chief Me	M.d	6	15.44	0	1	50	D
1/20/26 20:33	1/20/26	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rodman David Malcom	PA	O	Chief Me	S.d	-13	32.10	0	-1	50	D
1/20/26 20:21	1/15/26	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Yang Michael J.	CA	D		M.d	0	0.00	2	32	8	D
1/20/26 20:21	1/15/26	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Swayze Eric	CA	O	EVP Rese	M.d	0	0.00	21	103	42	M
1/20/26 20:21	1/16/26	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Swayze Eric	CA	O	EVP Rese	S.d	-748	75.34	-10	-19	42	M
1/20/26 20:21	1/15/26	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Schneider Eugene	CA	O	EVP,Chf	M.d	0	0.00	22	51	64	D
1/20/26 20:21	1/16/26	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Schneider Eugene	CA	O	EVP,Chf	S.d	-703	75.59	-9	-13	64	D
1/20/26 20:20	1/15/26	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	O'Neil Patrick R.	CA	O	EVP CLO,	M.d	0	0.00	21	48	66	D
1/20/26 20:20	1/16/26	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	O'Neil Patrick R.	CA	O	EVP CLO,	S.d	-697	75.84	-9	-12	66	D
1/20/26 20:20	1/15/26	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Monia Brett P	CA	DO	CEO	M.d	0	0.00	89	66	225	D
1/20/26 20:20	1/16/26	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Monia Brett P	CA	DO	CEO	S.d	-3,295	74.82	-44	-16	225	D
1/20/26 20:18	1/15/26	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Kordasiewicz Holly B.	CA	O	EVP,Chie	M.d	0	0.00	11	309	15	D
1/20/26 20:18	1/16/26	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Kordasiewicz Holly B.	CA	O	EVP,Chie	S.d	-313	75.66	-4	-22	15	D
1/20/26 20:18	1/15/26	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Jenne Kyle	CA	O	EVP,Chf	M.d	0	0.00	7	75	16	D
1/20/26 20:18	1/16/26	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Jenne Kyle	CA	O	EVP,Chf	S.d	-138	75.96	-2	-10	16	D
1/20/26 20:18	1/15/26	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Devers Shannon L.	CA	O	EVP,Chie	M.d	0	0.00	17	190	27	D
1/20/26 20:18	1/16/26	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Devers Shannon L.	CA	O	EVP,Chie	S.d	-634	75.95	-8	-24	27	D
1/20/26 20:18	1/15/26	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Birchler Brian	CA	O	EVP,Corp	M.d	0	0.00	20	50	60	D
1/20/26 20:18	1/16/26	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Birchler Brian	CA	O	EVP,Corp	S.d	-637	75.11	-8	-12	60	D
1/20/26 20:18	1/15/26	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	EVP,Chie	M.d	0	0.00	21	29	95	D
1/20/26 20:18	1/16/26	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	EVP,Chie	S.d	-675	75.15	-9	-9	95	D
1/20/26 20:18	1/15/26	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Baroldi Joseph	CA	O	EVP,Chie	M.d	0	0.00	20	79	45	M
1/20/26 20:18	1/16/26	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Baroldi Joseph	CA	O	EVP,Chie	S.d	-610	75.75	-8	-15	45	M
1/20/26 19:57	1/20/26	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ring Christine	CA	O	GC	M.d	7	1.86	4	8	51	D
1/20/26 19:57	1/20/26	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ring Christine	CA	O	GC	S.d	-69	18.42	-4	-7	51	D
1/20/26 19:19	1/16/26	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Heyman Richard A.	CA	D		S	-80	12.00	-7	-3	255	M
1/20/26 17:58	1/20/26	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kelley Shannon T	PA	O	GC	S	-344	497.36	-1	-8	8	D
1/20/26 17:46	1/20/26	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Taub Rebecca	PA	D		S	-1,098	490.77	-2	0	1,109	D
1/20/26 17:39	1/15/26	NKTX	Nkarta, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hastings Paul J	CA	DO	CEO	S	-54	2.07	-26	-6	390	D
1/20/26 17:38	1/15/26	NKTX	Nkarta, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mahmood Nadir	CA	O	P	S	-12	2.07	-6	-3	168	D
1/20/26 17:00	1/16/26	RPRX	Royalty Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Urist Marshall	NY	O	EVP,Rese	S	-790	39.52	-20	-23	66	I
1/20/26 16:52	1/15/26	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cohlhepp Ryan	MA	DO	P,COO	S	-3	18.02	0	0	214	D
1/20/26 16:33	1/15/26	DVAX	Dynavax Technologies Corp	DE	Health	Drug	Pharmaceutical Preparations	Novack David F	CA	O	P,COO	M.d	1,120	9.83	114		63	D
1/20/26 16:33	1/15/26	DVAX	Dynavax Technologies Corp	DE	Health	Drug	Pharmaceutical Preparations	Novack David F	CA	O	P,COO	S.d	-1,783	15.64	-114	-64	63	D
1/20/26 16:30	1/16/26	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Malcolm Jan	MD	D		S	-23	460.98	0	-14	0	D
1/20/26 16:30	1/16/26	ONCY	Oncolytics Biotech Inc		Health	Drug	Pharmaceutical Preparations	Seizinger Bernd R.	CA	D		P	104	1.04	100	27	467	D
1/20/26 16:30	1/12/26	TYRA	Tyra Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bensen Daniel	CA	O	Chief Di	S	-228	28.52	-8	-5	155	D
1/20/26 16:07	1/16/26	HOWL	Werewolf Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Evnin Luke	MA	D		S	-21	0.5400	-39	-2	2,160	I
1/20/26 16:01	1/19/26	IGC	Igc Pharma, Inc.	MD	Health	Drug	Pharmaceutical Preparations	Prins Richard K	MD	D		M.d	0	0.00	100	8	1,371	D
1/20/26 15:00	1/19/26	HRTX	Heron Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	Forbes William P	NC	O	EVP,Chie	M.d	0	0.00	4	2	170	D
1/20/26 14:49	1/19/26	HRTX	Heron Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	Duarte IRA	NC	O	EVP,CFO	M.d	0	0.00	4	2	184	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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