11/26/25 21:30 | 11/24/25 | CRMD | Cormedix Inc. | DE | Health | Drug | Pharmaceutical Preparations | Dillione Janet | NJ | D | | M.d | 96 | 3.64 | 0 | 26 | 119 | 48 | D | | | | | | | | | | | | | | |
11/26/25 21:30 | 11/24/25 | CRMD | Cormedix Inc. | DE | Health | Drug | Pharmaceutical Preparations | Dillione Janet | NJ | D | | S.d | -262 | 9.93 | 0 | -26 | -35 | 48 | D | | | | | | | | | | | | | | |
11/26/25 21:18 | 11/24/25 | FOLD | Amicus Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Castelli Jeff | NJ | O | Chief De | M.d | 452 | 9.03 | 0 | 50 | 13 | 439 | D | | | | | | | | | | | | | | |
11/26/25 21:18 | 11/24/25 | FOLD | Amicus Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Castelli Jeff | NJ | O | Chief De | S.d | -774 | 10.16 | 0 | -76 | -15 | 439 | D | | | | | | | | | | | | | | |
11/26/25 21:17 | 11/24/25 | FOLD | Amicus Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Clark David Michael | NJ | O | Chief Pe | S | -259 | 10.10 | 0 | -26 | -8 | 297 | D | | | | | | | | | | | | | | |
11/26/25 21:17 | 11/24/25 | FOLD | Amicus Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Campbell Bradley L | NJ | DO | P,CEO | M.d | 132 | 9.03 | 0 | 15 | 1 | 1,137 | D | | | | | | | | | | | | | | |
11/26/25 21:17 | 11/24/25 | FOLD | Amicus Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Campbell Bradley L | NJ | DO | P,CEO | S.d | -147 | 10.04 | 0 | -15 | -1 | 1,137 | D | | | | | | | | | | | | | | |
11/26/25 21:16 | 11/24/25 | FOLD | Amicus Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Rosenberg Ellen | NJ | O | GC | M.dm | 515 | 5.38 | 0 | 96 | 22 | 523 | D | | | | | | | | | | | | | | |
11/26/25 21:16 | 11/24/25 | FOLD | Amicus Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Rosenberg Ellen | NJ | O | GC | S.dm | -958 | 10.02 | 0 | -96 | -15 | 523 | D | | | | | | | | | | | | | | |
11/26/25 18:50 | 11/21/25 | KALV | Kalvista Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Piekos Brian | MA | O | CFO | M.d | 0 | 0.00 | 0 | 15 | | 11 | D | | | | | | | | | | | | | | |
11/26/25 18:50 | 11/24/25 | KALV | Kalvista Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Piekos Brian | MA | O | CFO | S.d | -60 | 13.45 | 0 | -4 | -30 | 11 | D | | | | | | | | | | | | | | |
11/26/25 18:49 | 11/21/25 | KALV | Kalvista Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Yea Christopher | MA | O | CHIEF DE | M.dm | 0 | 0.00 | 0 | 7 | 3 | 224 | D | | | | | | | | | | | | | | |
11/26/25 18:49 | 11/24/25 | KALV | Kalvista Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Yea Christopher | MA | O | CHIEF DE | S.d | -58 | 13.45 | 0 | -4 | -2 | 224 | D | | | | | | | | | | | | | | |
11/26/25 18:47 | 11/21/25 | KALV | Kalvista Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Audhya Paul K. | MA | O | CHIEF ME | M.dm | 0 | 0.00 | 0 | 11 | 9 | 132 | D | | | | | | | | | | | | | | |
11/26/25 18:47 | 11/24/25 | KALV | Kalvista Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Audhya Paul K. | MA | O | CHIEF ME | S.d | -71 | 13.45 | 0 | -5 | -4 | 132 | D | | | | | | | | | | | | | | |
11/26/25 18:46 | 11/21/25 | KALV | Kalvista Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Palleiko Benjamin L | MA | DO | CEO | M.d | 0 | 0.00 | 0 | 23 | 6 | 416 | D | | | | | | | | | | | | | | |
11/26/25 18:46 | 11/24/25 | KALV | Kalvista Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Palleiko Benjamin L | MA | DO | CEO | S.d | -147 | 13.45 | 0 | -11 | -3 | 416 | D | | | | | | | | | | | | | | |
11/26/25 18:45 | 11/24/25 | SION | Sionna Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D | | S.m | -4,814 | 44.55 | 0 | -108 | -3 | 3,597 | I | | | | | | | | | | | | | | |
11/26/25 18:41 | 11/24/25 | SION | Sionna Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Thompson Peter A. | MA | D | | S.m | -4,814 | 44.55 | 0 | -108 | -3 | 3,597 | I | | | | | | | | | | | | | | |
11/26/25 18:24 | 11/24/25 | ORGO | Organogenesis Holdings Inc. | DE | Health | Drug | Pharmaceutical Preparations | Nussdorf Glenn H | NY | DT | | S.m | -1,592 | 5.31 | 0 | -300 | -2 | 11,949 | D | | | | | | | | | | | | | | |
11/26/25 17:55 | 11/25/25 | NUVB | Nuvation Bio Inc. | DE | Health | Drug | Pharmaceutical Preparations | Liu Dongfang | NY | O | CHIEF ME | M.dm | 72 | 3.61 | 0 | 20 | | 18 | D | | | | | | | | | | | | | | |
11/26/25 17:55 | 11/25/25 | NUVB | Nuvation Bio Inc. | DE | Health | Drug | Pharmaceutical Preparations | Liu Dongfang | NY | O | CHIEF ME | S.dm | -155 | 7.75 | 0 | -20 | -53 | 18 | D | | | | | | | | | | | | | | |
11/26/25 17:46 | 11/25/25 | PAHC | Phibro Animal Health Corp | DE | Health | Drug | Pharmaceutical Preparations | Bendheim Jack | NJ | DOT | P,CEO | S.m | -542 | 43.97 | 0 | -12 | -20 | 51 | I | | | | | | | | | | | | | | |
11/26/25 17:22 | 11/25/25 | CORT | Corcept Therapeutics Inc | DE | Health | Drug | Pharmaceutical Preparations | Guyer William | CA | O | Chief De | S | -364 | 80.90 | 0 | -5 | -85 | 1 | D | | | | | | | | | | | | | | |
11/26/25 17:21 | 11/25/25 | SER | Serina Therapeutics, Inc. | AL | Health | Drug | Pharmaceutical Preparations | Moreadith Randall | AL | O | Chief Sc | M.d | 0 | 0.0600 | 0 | 6 | New | 6 | D | | | | | | | | | | | | | | |
11/26/25 17:21 | 11/25/25 | SER | Serina Therapeutics, Inc. | AL | Health | Drug | Pharmaceutical Preparations | Moreadith Randall | AL | O | Chief Sc | S.d | -23 | 3.90 | 0 | -6 | -50 | 6 | D | | | | | | | | | | | | | | |
11/26/25 17:01 | 11/24/25 | RPRX | Royalty Pharma Plc | X0 | Health | Drug | Pharmaceutical Preparations | Coyne Terrance P. | NY | O | EVP,CFO | S | -2,683 | 38.55 | 0 | -70 | -8 | 760 | I | | | | | | | | | | | | | | |
11/26/25 16:43 | 11/24/25 | MAIA | Maia Biotechnology, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Smith Stan | IL | D | | P.m | 25 | 0.9840 | 0 | 25 | 2 | 1,349 | I | | | | | | | | | | | | | | |
11/26/25 16:31 | 11/24/25 | INSM | Insmed Inc | VA | Health | Drug | Pharmaceutical Preparations | Anderson Elizabeth M | NJ | D | | S | -1,023 | 204.58 | 0 | -5 | -8 | 59 | D | | | | | | | | | | | | | | |
11/26/25 16:31 | 11/24/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Edgemond James | MD | O | CFO,TREA | M.d | 3,067 | 146.03 | 0 | 21 | | 8 | D | | | | | | | | | | | | | | |
11/26/25 16:31 | 11/24/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Edgemond James | MD | O | CFO,TREA | S.d | -9,947 | 473.65 | 0 | -21 | -72 | 8 | D | | | | | | | | | | | | | | |
11/26/25 16:30 | 11/24/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Benkowitz Michael | MD | O | P,COO | M.d | 3,084 | 137.07 | 0 | 23 | | 3 | I | | | | | | | | | | | | | | |
11/26/25 16:30 | 11/24/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Benkowitz Michael | MD | O | P,COO | S.d | -10,657 | 473.66 | 0 | -23 | -89 | 3 | I | | | | | | | | | | | | | | |
11/26/25 16:30 | 11/26/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Mahon Paul A | MD | O | EVP,GC | M.d | 1,490 | 135.42 | 0 | 11 | 43 | 37 | D | | | | | | | | | | | | | | |
11/26/25 16:30 | 11/26/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Mahon Paul A | MD | O | EVP,GC | S.d | -5,347 | 486.06 | 0 | -11 | -23 | 37 | D | | | | | | | | | | | | | | |
11/26/25 16:30 | 11/25/25 | ADTX | Aditxt, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Pankovcin Corinne | CA | O | Chief M, | S | 0 | 3.20 | 0 | 0 | -100 | 0 | D | | | | | | | | | | | | | | |
11/26/25 16:30 | 11/24/25 | NUVL | Nuvalent, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Shair Matthew | MA | D | | S | -820 | 109.37 | 0 | -8 | 0 | 1,579 | M | | | | | | | | | | | | | | |
11/26/25 16:07 | 11/26/25 | RCUS | Arcus Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Goeltz II Robert C. | CA | O | CFO | S | -125 | 25.00 | 0 | -5 | -5 | 87 | D | | | | | | | | | | | | | | |
11/26/25 16:06 | 11/24/25 | STOK | Stoke Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Krainer Adrian R. | MA | D | | S | -1,203 | 29.72 | 0 | -40 | -11 | 324 | D | | | | | | | | | | | | | | |
11/26/25 16:05 | 11/24/25 | SLGL | Sol-Gel Technologies Ltd. | L3 | Health | Drug | Pharmaceutical Preparations | Opaleye Management Inc. | MA | T | | P.m | 38 | 39.97 | 0 | 1 | 0 | 374 | I | | | | | | | | | | | | | | |
11/26/25 16:03 | 11/24/25 | AKRO | Akero Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Young Jonathan | CA | O | COO | M.d | 290 | 23.13 | 0 | 13 | 5 | 260 | D | | | | | | | | | | | | | | |
11/26/25 16:02 | 11/24/25 | OCUL | Ocular Therapeutix, Inc | DE | Health | Drug | Pharmaceutical Preparations | Nayak Sanjay | MA | O | Chief St | S | -23 | 12.04 | 0 | -2 | -1 | 278 | D | | | | | | | | | | | | | | |
11/26/25 16:02 | 11/24/25 | OCUL | Ocular Therapeutix, Inc | DE | Health | Drug | Pharmaceutical Preparations | Dugel Pravin | MA | DO | See Rema | S | -235 | 12.04 | 0 | -20 | -1 | 3,458 | M | | | | | | | | | | | | | | |
11/26/25 16:01 | 11/24/25 | OCUL | Ocular Therapeutix, Inc | DE | Health | Drug | Pharmaceutical Preparations | Kaiser Peter | MA | O | Chief De | S | -36 | 12.02 | 0 | -3 | -2 | 191 | D | | | | | | | | | | | | | | |
11/26/25 16:01 | 11/24/25 | OCUL | Ocular Therapeutix, Inc | DE | Health | Drug | Pharmaceutical Preparations | Heier Jeffrey S. | MA | O | Chief Sc | S | -42 | 12.04 | 0 | -3 | -1 | 246 | D | | | | | | | | | | | | | | |
11/26/25 16:00 | 11/25/25 | LLY | Eli Lilly & Co | IN | Health | Drug | Pharmaceutical Preparations | Lilly Endowment Inc | IN | T | | S.e | -3 | 0.2129 | 0 | -16 | 0 | 92,197 | D | | | | | | | | | | | | | | |
11/26/25 16:00 | 11/25/25 | LLY | Eli Lilly & Co | IN | Health | Drug | Pharmaceutical Preparations | Lilly Endowment Inc | IN | T | | S.e | -33 | 0.2228 | 0 | -147 | 0 | 92,213 | D | | | | | | | | | | | | | | |
11/26/25 14:58 | 11/26/25 | ABCL | Abcellera Biologics Inc. | A1 | Health | Drug | Pharmaceutical Preparations | Montalbano John S. | A1 | D | | P | 178 | 3.57 | 0 | 50 | 28 | 226 | D | | | | | | | | | | | | | | |
11/25/25 21:20 | 11/24/25 | SER | Serina Therapeutics, Inc. | AL | Health | Drug | Pharmaceutical Preparations | Moreadith Randall | AL | O | Chief Sc | M.d | 0 | 0.0600 | 0 | 1 | | 0 | D | | | | | | | | | | | | | | |
11/25/25 21:20 | 11/24/25 | SER | Serina Therapeutics, Inc. | AL | Health | Drug | Pharmaceutical Preparations | Moreadith Randall | AL | O | Chief Sc | S.d | -2 | 3.94 | 0 | -1 | -100 | 0 | D | | | | | | | | | | | | | | |
11/25/25 21:00 | 11/24/25 | TTRX | Turn Therapeutics Inc. | DE | Health | Drug | Pharmaceutical Preparations | Golden Arthur F | CA | D | | P | 34 | 3.44 | 0 | 10 | 19 | 61 | D | | | | | | | | | | | | | | |
11/25/25 20:30 | 11/25/25 | NKTR | Nektar Therapeutics | DE | Health | Drug | Pharmaceutical Preparations | Zalevsky Jonathan | CA | O | Chief R, | S.d | -63 | 54.28 | 0 | -1 | -6 | 19 | D | | | | | | | | | | | | | | |
11/25/25 20:29 | 11/25/25 | NKTR | Nektar Therapeutics | DE | Health | Drug | Pharmaceutical Preparations | Wilson Mark Andrew | CA | O | GC | S.d | -34 | 54.28 | 0 | -1 | -3 | 22 | D | | | | | | | | | | | | | | |
11/25/25 20:28 | 11/25/25 | NKTR | Nektar Therapeutics | DE | Health | Drug | Pharmaceutical Preparations | Robin Howard W | CA | DO | P,CEO | S.d | -120 | 54.28 | 0 | -2 | -4 | 54 | D | | | | | | | | | | | | | | |
11/25/25 20:17 | 11/25/25 | COCP | Cocrystal Pharma, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Frost Phillip Md Et Al | FL | DT | | P | 19 | 0.9406 | 0 | 20 | 1 | 1,727 | I | | | | | | | | | | | | | | |
11/25/25 19:38 | 11/25/25 | AMPH | Amphastar Pharmaceuticals, Inc. | | Health | Drug | Pharmaceutical Preparations | Prins Richard K | CA | D | | M.d | 70 | 16.69 | 0 | 4 | 13 | 35 | D | | | | | | | | | | | | | | |
11/25/25 19:38 | 11/25/25 | AMPH | Amphastar Pharmaceuticals, Inc. | | Health | Drug | Pharmaceutical Preparations | Prins Richard K | CA | D | | S.d | -113 | 27.10 | 0 | -4 | -11 | 35 | D | | | | | | | | | | | | | | |
11/25/25 19:00 | 11/25/25 | VRCA | Verrica Pharmaceuticals Inc. | DE | Health | Drug | Pharmaceutical Preparations | Rosenberg Noah L. | PA | O | CMO | P.d | 10 | 4.24 | 0 | 2 | New | 2 | D | | | | | | | | | | | | | | |
11/25/25 19:00 | 11/25/25 | VRCA | Verrica Pharmaceuticals Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kirby John J. | PA | O | Interim | P.d | 15 | 4.24 | 0 | 4 | 65 | 9 | D | | | | | | | | | | | | | | |
11/25/25 19:00 | 11/25/25 | VRCA | Verrica Pharmaceuticals Inc. | DE | Health | Drug | Pharmaceutical Preparations | Zawitz David | PA | O | COO | P.d | 42 | 4.24 | 0 | 10 | 91 | 21 | D | | | | | | | | | | | | | | |
11/25/25 19:00 | 11/25/25 | VRCA | Verrica Pharmaceuticals Inc. | DE | Health | Drug | Pharmaceutical Preparations | Rieger Jayson | PA | DO | CEO,P | P.d | 400 | 4.24 | 0 | 94 | 106 | 183 | D | | | | | | | | | | | | | | |
11/25/25 19:00 | 11/25/25 | VRCA | Verrica Pharmaceuticals Inc. | DE | Health | Drug | Pharmaceutical Preparations | Manning Paul B | VA | DT | | P.d | 17,505 | 4.24 | 0 | 4,126 | 108 | 7,932 | M | | | | | | | | | | | | | | |
11/25/25 18:59 | 11/24/25 | ANVS | Annovis Bio, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Hoffman Michael B | PA | D | | P.a | 160 | 4.08 | 0 | 39 | 1 | 2,753 | D | | | | | | | | | | | | | | |
11/25/25 18:42 | 11/21/25 | BCAX | Bicara Therapeutics Inc. | DE | Health | Drug | Pharmaceutical Preparations | Hyep Ivan | MA | O | CFO | M.dm | 70 | 3.79 | 0 | 18 | 14 | 145 | D | | | | | | | | | | | | | | |
11/25/25 18:42 | 11/21/25 | BCAX | Bicara Therapeutics Inc. | DE | Health | Drug | Pharmaceutical Preparations | Hyep Ivan | MA | O | CFO | S.dm | -341 | 18.54 | 0 | -18 | -11 | 145 | D | | | | | | | | | | | | | | |
11/25/25 18:41 | 11/21/25 | BCAX | Bicara Therapeutics Inc. | DE | Health | Drug | Pharmaceutical Preparations | Cohlhepp Ryan | MA | DO | P,COO | M.d | 30 | 3.79 | 0 | 8 | 4 | 194 | D | | | | | | | | | | | | | | |
11/25/25 18:41 | 11/21/25 | BCAX | Bicara Therapeutics Inc. | DE | Health | Drug | Pharmaceutical Preparations | Cohlhepp Ryan | MA | DO | P,COO | S.d | -226 | 18.05 | 0 | -13 | -6 | 194 | D | | | | | | | | | | | | | | |
11/25/25 18:40 | 11/24/25 | BCAX | Bicara Therapeutics Inc. | DE | Health | Drug | Pharmaceutical Preparations | Mazumdar Claire | MA | DO | CEO | M.d | 156 | 3.79 | 0 | 41 | 15 | 310 | D | | | | | | | | | | | | | | |
11/25/25 18:40 | 11/24/25 | BCAX | Bicara Therapeutics Inc. | DE | Health | Drug | Pharmaceutical Preparations | Mazumdar Claire | MA | DO | CEO | S.d | -776 | 18.86 | 0 | -41 | -12 | 310 | D | | | | | | | | | | | | | | |
11/25/25 18:39 | 11/24/25 | BCAX | Bicara Therapeutics Inc. | DE | Health | Drug | Pharmaceutical Preparations | Raben David | MA | O | Chief Me | M.dm | 42 | 3.79 | 0 | 11 | 45 | 35 | D | | | | | | | | | | | | | | |
11/25/25 18:39 | 11/24/25 | BCAX | Bicara Therapeutics Inc. | DE | Health | Drug | Pharmaceutical Preparations | Raben David | MA | O | Chief Me | S.dm | -205 | 18.65 | 0 | -11 | -24 | 35 | D | | | | | | | | | | | | | | |
11/25/25 18:27 | 11/24/25 | ARQT | Arcutis Biotherapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Lin Sue-Jean | CA | D | | M.d | 210 | 8.31 | 0 | 25 | 999% | 27 | D | | | | | | | | | | | | | | |
11/25/25 18:27 | 11/24/25 | ARQT | Arcutis Biotherapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Lin Sue-Jean | CA | D | | S.d | -778 | 30.78 | 0 | -25 | -49 | 27 | D | | | | | | | | | | | | | | |
11/25/25 18:08 | 11/25/25 | EQ | Equillium, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Zedelmayer Christine | CA | O | SVP,COO | S | -8 | 0.9504 | 0 | -8 | -6 | 127 | D | | | | | | | | | | | | | | |
11/25/25 18:05 | 11/21/25 | HOWL | Werewolf Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Evnin Luke | MA | D | | S.m | -115 | 0.9176 | 0 | -126 | -4 | 3,288 | I | | | | | | | | | | | | | | |
11/25/25 18:04 | 11/21/25 | HOWL | Werewolf Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Mpm Bioventures 2014, L.P. | MA | T | | S.m | -180 | 0.9176 | 0 | -196 | -4 | 5,126 | I | | | | | | | | | | | | | | |
11/25/25 18:03 | 11/21/25 | HOWL | Werewolf Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Gadicke Ansbert | MA | T | | S.m | -180 | 0.9176 | 0 | -196 | -4 | 5,126 | I | | | | | | | | | | | | | | |
11/25/25 18:00 | 11/21/25 | OLMA | Olema Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Rappaport Andrew | CA | D | | M.d | 14 | 0.3900 | 0 | 36 | 10 | 386 | D | | | | | | | | | | | | | | |
11/25/25 17:35 | 11/21/25 | VSTM | Verastem, Inc. | MA | Health | Drug | Pharmaceutical Preparations | Bunn Paul A. | MA | D | | S.d | -63 | 10.00 | 0 | -6 | -43 | 8 | D | | | | | | | | | | | | | | |
11/25/25 17:35 | 11/21/25 | VSTM | Verastem, Inc. | MA | Health | Drug | Pharmaceutical Preparations | Bunn Paul A. | MA | D | | M.d | 20 | 3.27 | 0 | 6 | 300 | 8 | D | | | | | | | | | | | | | | |
11/25/25 17:34 | 11/21/25 | VSTM | Verastem, Inc. | MA | Health | Drug | Pharmaceutical Preparations | Kauffman Michael | MA | D | | S | -86 | 10.00 | 0 | -9 | -50 | 9 | D | | | | | | | | | | | | | | |
11/25/25 17:32 | 11/21/25 | VSTM | Verastem, Inc. | MA | Health | Drug | Pharmaceutical Preparations | Paterson Dan | MA | DO | P,CEO | S.m | -60 | 10.00 | 0 | -6 | -1 | 433 | D | | | | | | | | | | | | | | |
11/25/25 17:31 | 11/24/25 | TGTX | Tg Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Echelard Yann | NC | D | | S | -163 | 32.57 | 0 | -5 | -2 | 224 | D | | | | | | | | | | | | | | |
11/25/25 17:00 | 11/21/25 | TYRA | Tyra Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | More Robert J | CA | D | | S | -5,000 | 20.25 | 0 | -247 | -6 | 3,833 | I | | | | | | | | | | | | | | |
11/25/25 16:49 | 11/24/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Rothblatt Martine A | MD | DO | CHAIRPER | M.dm | 962 | 120.26 | 0 | 8 | 1 | 644 | D | | | | | | | | | | | | | | |
11/25/25 16:49 | 11/24/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Rothblatt Martine A | MD | DO | CHAIRPER | S.dm | -3,784 | 473.05 | 0 | -8 | -1 | 644 | D | | | | | | | | | | | | | | |
11/25/25 16:44 | 11/21/25 | ARDX | Ardelyx, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Grammer Elizabeth A | MA | O | See Rema | S | -33 | 5.54 | 0 | -6 | -2 | 300 | D | | | | | | | | | | | | | | |
11/25/25 16:42 | 11/21/25 | ARDX | Ardelyx, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Raab Michael | MA | DO | P,CEO | S | -260 | 5.54 | 0 | -47 | -3 | 1,481 | D | | | | | | | | | | | | | | |
11/25/25 16:38 | 11/21/25 | ARDX | Ardelyx, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kelliher Mike | MA | O | See Rema | S | -31 | 5.54 | 0 | -6 | -2 | 271 | D | | | | | | | | | | | | | | |
11/25/25 16:35 | 11/21/25 | ARDX | Ardelyx, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Williams Laura A | MA | O | Chief Pa | S | -36 | 5.54 | 0 | -6 | -2 | 360 | D | | | | | | | | | | | | | | |
11/25/25 16:30 | 11/21/25 | DMAC | Diamedica Therapeutics Inc. | Z4 | Health | Drug | Pharmaceutical Preparations | Parsons James T. | MN | D | | M.d | 26 | 2.20 | 0 | 12 | 16 | 88 | D | | | | | | | | | | | | | | |
11/25/25 16:22 | 11/21/25 | ARDX | Ardelyx, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Foster Eric Duane | MA | O | Chief Co | S | -32 | 5.54 | 0 | -6 | -2 | 296 | D | | | | | | | | | | | | | | |
11/25/25 16:21 | 11/21/25 | ARDX | Ardelyx, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Reilly Joseph James | MA | O | See Rema | S | -61 | 5.54 | 0 | -11 | -9 | 109 | D | | | | | | | | | | | | | | |
11/25/25 16:17 | 11/25/25 | ABT | Abbott Laboratories | IL | Health | Drug | Pharmaceutical Preparations | Shroff Eric | IL | O | SVP | S | -203 | 128.02 | 0 | -2 | -5 | 30 | D | | | | | | | | | | | | | | |
11/25/25 16:15 | 11/21/25 | MAIA | Maia Biotechnology, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Vitoc Vlad | IL | DOT | CEO | P.m | 12 | 0.9786 | 0 | 12 | 1 | 1,031 | D | | | | | | | | | | | | | | |
11/25/25 16:11 | 11/21/25 | ZLAB | Zai Lab Ltd | E9 | Health | Drug | Pharmaceutical Preparations | Edmondson Frazor Titus III | MA | O | GC | S | -283 | 19.78 | 0 | -14 | -34 | 28 | D | | | | | | | | | | | | | | |
11/25/25 16:10 | 11/21/25 | MIRM | Mirum Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Grey Michael G | CA | D | | M.d | 147 | 2.94 | 0 | 50 | 22 | 280 | D | | | | | | | | | | | | | | |
11/25/25 16:10 | 11/21/25 | MIRM | Mirum Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Grey Michael G | CA | D | | S.d | -3,500 | 70.00 | 0 | -50 | -15 | 280 | D | | | | | | | | | | | | | | |
11/25/25 16:10 | 11/21/25 | HRMY | Harmony Biosciences Holdings, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kapadia Sandip | PA | O | CFO | S | -120 | 35.00 | 0 | -3 | -100 | 0 | D | | | | | | | | | | | | | | |
11/25/25 16:06 | 11/24/25 | SAVA | Cassava Sciences Inc | DE | Health | Drug | Pharmaceutical Preparations | Anderson Robert Eugene Jr | TX | D | | P | 25 | 2.90 | 0 | 9 | New | 9 | D | | | | | | | | | | | | | | |
11/25/25 16:05 | 11/21/25 | VERA | Vera Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Carter Jason S | CA | O | GC | S | -107 | 27.82 | 0 | -4 | -7 | 49 | D | | | | | | | | | | | | | | |
11/25/25 16:02 | 11/21/25 | ALMS | Alumis Inc. | DE | Health | Drug | Pharmaceutical Preparations | Foresite Capital Management VI LLC | CA | T | | P | 533 | 7.38 | 0 | 72 | 0 | 15,778 | I | | | | | | | | | | | | | | |
11/25/25 16:02 | 11/21/25 | ALMS | Alumis Inc. | DE | Health | Drug | Pharmaceutical Preparations | Tananbaum James B. | CA | DT | | P | 533 | 7.38 | 0 | 72 | 0 | 15,778 | I | | | | | | | | | | | | | | |
11/25/25 16:01 | 11/21/25 | ALMS | Alumis Inc. | DE | Health | Drug | Pharmaceutical Preparations | Foresite Labs, LLC | CA | T | | P | 533 | 7.38 | 0 | 72 | 0 | 15,778 | I | | | | | | | | | | | | | | |
11/25/25 16:00 | 11/24/25 | LLY | Eli Lilly & Co | IN | Health | Drug | Pharmaceutical Preparations | Lilly Endowment Inc | IN | T | | S.e | -6 | 0.0452 | 0 | -142 | 0 | 92,360 | D | | | | | | | | | | | | | | |
11/25/25 12:54 | 11/21/25 | CVRX | Cvrx, Inc. | NJ | Health | Drug | Pharmaceutical Preparations | Johnson & Johnson | NJ | T | | S.m | -27 | 10.05 | 0 | -3 | 0 | 4,047 | I | | | | | | | | | | | | | | |
11/25/25 12:26 | 11/24/25 | ANVS | Annovis Bio, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Hoffman Michael B | PA | D | | P | 160 | 4.08 | 0 | 39 | 1 | 2,743 | D | | | | | | | | | | | | | | |
11/24/25 21:10 | 11/21/25 | NTHI | Neonc Technologies Holdings, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Heshmatpour Amir F | CA | DOT | P | P.m | 185 | 6.16 | 0 | 30 | 0 | 10,494 | D | | | | | | | | | | | | | | |
11/24/25 20:08 | 11/21/25 | CPRX | Catalyst Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Sundaram Preethi | FL | O | Chief St | M.d | 0 | 0.00 | 0 | 6 | 14 | 45 | D | | | | | | | | | | | | | | |
11/24/25 20:08 | 11/21/25 | CPRX | Catalyst Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Miller Steve | FL | O | Chief Op | M.d | 0 | 0.00 | 0 | 8 | 1 | 1,068 | D | | | | | | | | | | | | | | |
11/24/25 20:08 | 11/21/25 | CPRX | Catalyst Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Thompson Tamar | FL | D | | M.d | 0 | 0.00 | 0 | 1 | 67 | 2 | D | | | | | | | | | | | | | | |
11/24/25 20:08 | 11/21/25 | CPRX | Catalyst Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kalb Michael Wayne | FL | O | EVP,CFO | M.d | 0 | 0.00 | 0 | 7 | 403 | 9 | D | | | | | | | | | | | | | | |
11/24/25 20:08 | 11/21/25 | CPRX | Catalyst Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Tierney David S | FL | D | | M.d | 0 | 0.00 | 0 | 1 | 0 | 381 | D | | | | | | | | | | | | | | |
11/24/25 20:08 | 11/21/25 | CPRX | Catalyst Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | McEnany Patrick J | FL | DH | Chairman | M.d | 0 | 0.00 | 0 | 2 | 0 | 4,283 | D | | | | | | | | | | | | | | |
11/24/25 20:08 | 11/21/25 | CPRX | Catalyst Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Harper Molly | FL | D | | M.d | 0 | 0.00 | 0 | 1 | 14 | 8 | D | | | | | | | | | | | | | | |
11/24/25 20:08 | 11/21/25 | CPRX | Catalyst Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Daly Richard J | FL | DO | P,CEO | M.d | 0 | 0.00 | 0 | 20 | 9 | 239 | D | | | | | | | | | | | | | | |
11/24/25 20:08 | 11/21/25 | CPRX | Catalyst Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Denkhaus Donald A | FL | D | | M.d | 0 | 0.00 | 0 | 1 | 0 | 496 | D | | | | | | | | | | | | | | |
11/24/25 20:08 | 11/21/25 | CPRX | Catalyst Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Elsbernd Brian | FL | O | Chief Co | M.d | 0 | 0.00 | 0 | 5 | 2 | 234 | D | | | | | | | | | | | | | | |
11/24/25 20:08 | 11/21/25 | CPRX | Catalyst Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Del Carmen Jeffrey | FL | O | Chief Co | M.d | 0 | 0.00 | 0 | 6 | | 4 | D | | | | | | | | | | | | | | |
11/24/25 20:00 | 11/24/25 | NUVL | Nuvalent, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Flynn James E | NY | DTH | Director | S | -70,875 | 95.45 | 0 | -743 | -4 | 17,248 | I | | | | | | | | | | | | | | |
11/24/25 18:50 | 11/20/25 | ALMS | Alumis Inc. | DE | Health | Drug | Pharmaceutical Preparations | Akkaraju Srinivas | CA | D | | P | 905 | 7.20 | 0 | 126 | 3 | 5,135 | I | | | | | | | | | | | | | | |
11/24/25 18:46 | 11/20/25 | BBIO | Bridgebio Pharma, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kumar Neil | CA | DO | CEO | S | -1,722 | 65.84 | 0 | -26 | 0 | 5,623 | D | | | | | | | | | | | | | | |
11/24/25 18:45 | 11/21/25 | ARQT | Arcutis Biotherapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Watanabe Todd | CA | DO | See Rema | S.m | -1,517 | 30.35 | 0 | -50 | -5 | 974 | D | | | | | | | | | | | | | | |
11/24/25 18:16 | 11/21/25 | SUPN | Supernus Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Newhall Charles W III | MD | D | | M.d | 195 | 12.98 | 0 | 15 | 14 | 120 | D | | | | | | | | | | | | | | |
11/24/25 18:06 | 11/24/25 | NRIX | Nurix Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Ring Christine | CA | O | GC | M.d | 70 | 1.86 | 0 | 38 | 283 | 51 | D | | | | | | | | | | | | | | |
11/24/25 18:06 | 11/24/25 | NRIX | Nurix Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Ring Christine | CA | O | GC | S.d | -642 | 17.07 | 0 | -38 | -42 | 51 | D | | | | | | | | | | | | | | |
11/24/25 18:00 | 11/21/25 | RNXT | Renovorx, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Agah Ramtin | CA | DO | Chief Me | P.m | 18 | 0.8000 | 0 | 22 | 3 | 756 | D | | | | | | | | | | | | | | |
11/24/25 17:47 | 11/20/25 | JAZZ | Jazz Pharmaceuticals Plc | L2 | Health | Drug | Pharmaceutical Preparations | McSharry Heather Ann | L2 | D | | M.d | 472 | 138.08 | 0 | 3 | 20 | 20 | D | | | | | | | | | | | | | | |
11/24/25 17:47 | 11/20/25 | JAZZ | Jazz Pharmaceuticals Plc | L2 | Health | Drug | Pharmaceutical Preparations | McSharry Heather Ann | L2 | D | | S.d | -607 | 177.78 | 0 | -3 | -14 | 20 | D | | | | | | | | | | | | | | |
11/24/25 17:46 | 11/20/25 | NTHI | Neonc Technologies Holdings, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Neman-Ebrahim Yousha | CA | O | Chief Cl | P | 7 | 6.69 | 0 | 1 | 1 | 134 | D | | | | | | | | | | | | | | |
11/24/25 17:43 | 11/20/25 | SION | Sionna Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Ra Capital Management, L.P. | MA | DT | | S.m | -1,201 | 39.61 | 0 | -30 | -16 | 159 | I | | | | | | | | | | | | | | |
11/24/25 17:08 | 11/20/25 | SLRX | Salarius Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Hanish Arnold C | TX | D | | P | 4 | 0.7481 | 0 | 5 | 999% | 5 | I | | | | | | | | | | | | | | |
11/24/25 17:07 | 11/21/25 | MLYS | Mineralys Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Congleton Jon | PA | DO | CEO | M.d | 13 | 0.5400 | 0 | 24 | 4 | 655 | D | | | | | | | | | | | | | | |
11/24/25 16:42 | 11/20/25 | GRTX | Galera Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Sorensen Mel | PA | DO | P,CEO | S | -1 | 0.0201 | 0 | -70 | -26 | 195 | D | | | | | | | | | | | | | | |
11/24/25 16:30 | 11/21/25 | TRDA | Entrada Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Wentworth Kory James | MA | O | CFO | S | -89 | 9.98 | 0 | -9 | -7 | 110 | D | | | | | | | | | | | | | | |
11/24/25 16:15 | 11/20/25 | RYTM | Rhythm Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Cramer Pamela J. | MA | O | CHRO | M.d | 92 | 27.35 | 0 | 3 | 19 | 21 | D | | | | | | | | | | | | | | |
11/24/25 16:15 | 11/20/25 | RYTM | Rhythm Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Cramer Pamela J. | MA | O | CHRO | S.d | -352 | 105.00 | 0 | -3 | -14 | 21 | D | | | | | | | | | | | | | | |
11/24/25 16:15 | 11/20/25 | PAHC | Phibro Animal Health Corp | DE | Health | Drug | Pharmaceutical Preparations | Bendheim Jack | NJ | DOT | P,CEO | S | -147 | 41.76 | 0 | -4 | -5 | 63 | I | | | | | | | | | | | | | | |
11/24/25 16:09 | 11/20/25 | TRDA | Entrada Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Baker Bros. Advisors LP | NY | T | | P | 262 | 9.07 | 0 | 29 | 1 | 4,691 | I | | | | | | | | | | | | | | |
11/24/25 16:09 | 11/20/25 | NUVB | Nuvation Bio Inc. | DE | Health | Drug | Pharmaceutical Preparations | Hattersley Gary | NY | O | Chief Sc | M.d | 702 | 1.90 | 0 | 369 | | 0 | D | | | | | | | | | | | | | | |
11/24/25 16:09 | 11/20/25 | NUVB | Nuvation Bio Inc. | DE | Health | Drug | Pharmaceutical Preparations | Hattersley Gary | NY | O | Chief Sc | S.d | -2,667 | 7.23 | 0 | -369 | -100 | 0 | D | | | | | | | | | | | | | | |
11/24/25 16:08 | 11/20/25 | NUVB | Nuvation Bio Inc. | DE | Health | Drug | Pharmaceutical Preparations | Liu Dongfang | NY | O | CHIEF ME | M.d | 37 | 1.87 | 0 | 20 | | 18 | D | | | | | | | | | | | | | | |
11/24/25 16:08 | 11/20/25 | NUVB | Nuvation Bio Inc. | DE | Health | Drug | Pharmaceutical Preparations | Liu Dongfang | NY | O | CHIEF ME | S.d | -140 | 7.00 | 0 | -20 | -53 | 18 | D | | | | | | | | | | | | | | |
11/24/25 16:07 | 11/20/25 | REGN | Regeneron Pharmaceuticals, Inc. | NY | Health | Drug | Pharmaceutical Preparations | Larosa Joseph J | NY | O | EVP GC,S | M.d | 8,029 | 555.67 | 0 | 14 | 54 | 41 | D | | | | | | | | | | | | | | |
11/24/25 16:05 | 11/20/25 | REGN | Regeneron Pharmaceuticals, Inc. | NY | Health | Drug | Pharmaceutical Preparations | Bassler Bonnie L | NY | D | | M.d | 282 | 371.40 | 0 | 1 | 96 | 2 | D | | | | | | | | | | | | | | |
11/24/25 16:05 | 11/20/25 | REGN | Regeneron Pharmaceuticals, Inc. | NY | Health | Drug | Pharmaceutical Preparations | Bassler Bonnie L | NY | D | | S.d | -570 | 750.00 | 0 | -1 | -33 | 2 | D | | | | | | | | | | | | | | |
11/24/25 16:03 | 11/20/25 | TEVA | Teva Pharmaceutical Industries Ltd | L3 | Health | Drug | Pharmaceutical Preparations | Fox Christine | L3 | O | EVP,Head | M.d | 0 | 0.00 | 0 | 63 | 999% | 64 | D | | | | | | | | | | | | | | |
11/24/25 16:03 | 11/20/25 | TEVA | Teva Pharmaceutical Industries Ltd | L3 | Health | Drug | Pharmaceutical Preparations | Fox Christine | L3 | O | EVP,Head | S.d | -700 | 24.78 | 0 | -28 | -31 | 64 | D | | | | | | | | | | | | | | |
11/24/25 16:02 | 11/20/25 | SAVA | Cassava Sciences Inc | DE | Health | Drug | Pharmaceutical Preparations | Barry Richard | TX | DO | P,CEO | P | 414 | 2.76 | 0 | 150 | 19 | 938 | I | | | | | | | | | | | | | | |
11/24/25 16:00 | 11/21/25 | LLY | Eli Lilly & Co | IN | Health | Drug | Pharmaceutical Preparations | Lilly Endowment Inc | IN | T | | S.e | -18 | 0.1708 | 0 | -105 | 0 | 92,502 | D | | | | | | | | | | | | | | |
11/24/25 12:54 | 11/21/25 | PHIO | Phio Pharmaceuticals Corp. | DE | Health | Drug | Pharmaceutical Preparations | Bitterman Robert J | PA | DO | CB,P,CEO | P | 6 | 1.14 | 0 | 5 | 2 | 281 | D | | | | | | | | | | | | | | |
11/24/25 07:13 | 11/21/25 | TTRX | Turn Therapeutics Inc. | DE | Health | Drug | Pharmaceutical Preparations | Golden Arthur F | CA | D | | P | 59 | 2.87 | 0 | 21 | 68 | 51 | D | | | | | | | | | | | | | | |
11/21/25 21:52 | 11/20/25 | ANNX | Annexon, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Satter Muneer A | CA | D | | P.m | 3,601 | 4.38 | 0 | 823 | 9 | 9,729 | I | | | | | | | | | | | | | | |
11/21/25 21:41 | 11/20/25 | PRAX | Praxis Precision Medicines, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Nemiroff Alex | MA | O | GC,Secre | M.d | 1,854 | 73.76 | 0 | 25 | | 21 | D | | | | | | | | | | | | | | |
11/21/25 21:41 | 11/20/25 | PRAX | Praxis Precision Medicines, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Nemiroff Alex | MA | O | GC,Secre | S.d | -4,852 | 193.09 | 0 | -25 | -55 | 21 | D | | | | | | | | | | | | | | |
11/21/25 21:39 | 11/20/25 | PRAX | Praxis Precision Medicines, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Mastrocola Lauren | MA | O | Principa | M.d | 831 | 61.12 | 0 | 14 | | 10 | D | | | | | | | | | | | | | | |
11/21/25 21:39 | 11/20/25 | PRAX | Praxis Precision Medicines, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Mastrocola Lauren | MA | O | Principa | S.d | -2,612 | 192.08 | 0 | -14 | -57 | 10 | D | | | | | | | | | | | | | | |
11/21/25 20:24 | 11/19/25 | ROIV | Roivant Sciences Ltd. | D0 | Health | Drug | Pharmaceutical Preparations | Manchester Keith S | X0 | D | | S | -26,305 | 20.23 | 0 | -1,300 | -7 | 18,048 | I | | | | | | | | | | | | | | |
11/21/25 20:22 | 11/19/25 | ROIV | Roivant Sciences Ltd. | D0 | Health | Drug | Pharmaceutical Preparations | Gold Daniel Allen | X0 | D | | S | -26,305 | 20.23 | 0 | -1,300 | -7 | 18,048 | I | | | | | | | | | | | | | | |
11/21/25 20:15 | 11/19/25 | ROIV | Roivant Sciences Ltd. | D0 | Health | Drug | Pharmaceutical Preparations | Qvt Financial LP | NY | H | Director | S | -26,305 | 20.23 | 0 | -1,300 | -7 | 18,048 | I | | | | | | | | | | | | | | |
11/21/25 19:57 | 11/21/25 | ANVS | Annovis Bio, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Hoffman Michael B | PA | D | | P | 70 | 3.50 | 0 | 20 | 1 | 2,714 | D | | | | | | | | | | | | | | |
11/21/25 19:54 | 11/19/25 | PGEN | Precigen, Inc. | VA | Health | Drug | Pharmaceutical Preparations | Kirk Randal J | VA | DT | | S.m | -12,292 | 4.14 | 0 | -2,966 | -2 | 123,946 | I | | | | | | | | | | | | | | |
11/21/25 18:35 | 11/20/25 | SILO | Silo Pharma, Inc. | NV | Health | Drug | Pharmaceutical Preparations | Weisblum Eric | FL | DO | CEO | P.m | 1 | 0.3675 | 0 | 2 | 1 | 212 | D | | | | | | | | | | | | | | |
11/21/25 18:34 | 11/19/25 | ARQT | Arcutis Biotherapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Matsuda Masaru | CA | O | See Rema | S | -72 | 28.29 | 0 | -3 | -2 | 151 | D | | | | | | | | | | | | | | |
11/21/25 18:21 | 11/20/25 | ARQT | Arcutis Biotherapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Gilbert Halley E | CA | D | | M.d | 92 | 7.51 | 0 | 12 | 123 | 22 | D | | | | | | | | | | | | | | |
11/21/25 18:21 | 11/20/25 | ARQT | Arcutis Biotherapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Gilbert Halley E | CA | D | | S.d | -455 | 27.55 | 0 | -17 | -43 | 22 | D | | | | | | | | | | | | | | |
11/21/25 18:13 | 11/20/25 | SGMT | Sagimet Biosciences Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kemble George | CA | DO | Exec CB | S | -290 | 7.69 | 0 | -38 | -32 | 81 | D | | | | | | | | | | | | | | |
11/21/25 18:07 | 11/20/25 | MLYS | Mineralys Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Slingsby Brian Taylor | WA | DT | | S | -43,350 | 43.35 | 0 | -1,000 | -11 | 7,904 | I | | | | | | | | | | | | | | |
11/21/25 17:43 | 11/20/25 | TTRX | Turn Therapeutics Inc. | DE | Health | Drug | Pharmaceutical Preparations | Chaudhary Zuraiz | CA | O | See Rema | P.m | 7 | 2.89 | 0 | 2 | 32 | 10 | D | | | | | | | | | | | | | | |
11/21/25 17:39 | 11/21/25 | MDGL | Madrigal Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Huntsman Carole | PA | O | Chief Co | S | -1,083 | 553.11 | 0 | -2 | -16 | 10 | D | | | | | | | | | | | | | | |
11/21/25 17:28 | 11/19/25 | ELVN | Enliven Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Lyssikatos Joseph P | CO | O | CHIEF SC | S | -279 | 22.33 | 0 | -13 | -1 | 903 | I | | | | | | | | | | | | | | |
11/21/25 17:26 | 11/20/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Rothblatt Martine A | MD | DO | CHAIRPER | M.dm | 962 | 120.26 | 0 | 8 | 1 | 644 | D | | | | | | | | | | | | | | |
11/21/25 17:26 | 11/20/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Rothblatt Martine A | MD | DO | CHAIRPER | S.dm | -3,812 | 476.51 | 0 | -8 | -1 | 644 | D | | | | | | | | | | | | | | |
11/21/25 17:07 | 11/21/25 | OPK | Opko Health, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Frost Phillip Md Et Al | FL | DOT | CEO,CB | P | 769 | 1.33 | 0 | 580 | 0 | 250,403 | I | | | | | | | | | | | | | | |
11/21/25 17:00 | 10/31/25 | GBIO | Generation Bio Co. | DE | Health | Drug | Pharmaceutical Preparations | McDonough Geoff | MA | D | | M.d | 0 | 0.00 | 0 | 1 | 0 | 187 | D | | | | | | | | | | | | | | |
11/21/25 16:59 | 11/19/25 | LFVN | Lifevantage Corp | | Health | Drug | Pharmaceutical Preparations | Beindorff Michael A | UT | D | | S | -81 | 6.42 | 0 | -13 | -13 | 85 | I | | | | | | | | | | | | | | |
11/21/25 16:55 | 11/19/25 | RPRX | Royalty Pharma Plc | X0 | Health | Drug | Pharmaceutical Preparations | Lloyd George W. | NY | O | EVP,Inve | S | -5,193 | 38.34 | 0 | -135 | -12 | 1,000 | M | | | | | | | | | | | | | | |
11/21/25 16:25 | 11/19/25 | PVLA | Palvella Therapeutics, Inc. | NV | Health | Drug | Pharmaceutical Preparations | Goin Kathleen | PA | O | COO | M.d | 35 | 8.11 | 0 | 4 | | 0 | D | | | | | | | | | | | | | | |
11/21/25 16:25 | 11/19/25 | PVLA | Palvella Therapeutics, Inc. | NV | Health | Drug | Pharmaceutical Preparations | Goin Kathleen | PA | O | COO | S.d | -371 | 86.23 | 0 | -4 | -100 | 0 | D | | | | | | | | | | | | | | |
11/21/25 16:15 | 11/19/25 | FULC | Fulcrum Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Gould Robert J | MA | D | | S | -165 | 11.03 | 0 | -15 | -3 | 485 | D | | | | | | | | | | | | | | |
11/21/25 16:07 | 11/20/25 | KALV | Kalvista Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Yea Christopher | MA | O | CHIEF DE | M.d | 0 | 0.0043 | 0 | 87 | 65 | 221 | D | | | | | | | | | | | | | | |
11/21/25 16:05 | 11/20/25 | SLGL | Sol-Gel Technologies Ltd. | L3 | Health | Drug | Pharmaceutical Preparations | Opaleye Management Inc. | MA | T | | P | 207 | 35.83 | 0 | 6 | 2 | 373 | I | | | | | | | | | | | | | | |
11/21/25 16:05 | 11/19/25 | NUVB | Nuvation Bio Inc. | DE | Health | Drug | Pharmaceutical Preparations | Hanley David C. | NY | O | CHIEF TE | M.d | 374 | 1.87 | 0 | 200 | | 24 | D | | | | | | | | | | | | | | |
11/21/25 16:05 | 11/19/25 | NUVB | Nuvation Bio Inc. | DE | Health | Drug | Pharmaceutical Preparations | Hanley David C. | NY | O | CHIEF TE | S.d | -1,428 | 7.14 | 0 | -200 | -89 | 24 | D | | | | | | | | | | | | | | |
11/21/25 16:00 | 11/20/25 | LLY | Eli Lilly & Co | IN | Health | Drug | Pharmaceutical Preparations | Lilly Endowment Inc | IN | T | | S.e | -6 | 0.1701 | 0 | -37 | 0 | 92,607 | D | | | | | | | | | | | | | | |
11/21/25 08:45 | 11/19/25 | SLS | Sellas Life Sciences Group, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kalin Katherine Bach | NY | D | | P | 101 | 1.59 | 0 | 63 | 155 | 104 | D | | | | | | | | | | | | | | |
11/20/25 20:03 | 11/18/25 | JAZZ | Jazz Pharmaceuticals Plc | L2 | Health | Drug | Pharmaceutical Preparations | Cozadd Bruce C | L2 | D | | S | -3,260 | 181.09 | 0 | -18 | -4 | 393 | D | | | | | | | | | | | | | | |
11/20/25 18:38 | 11/18/25 | TENX | Tenax Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Giordano Christopher Thomas | NC | DO | CEO | P.dm | 20 | 7.68 | 0 | 3 | New | 3 | D | | | | | | | | | | | | | | |
11/20/25 18:16 | 11/17/25 | TENX | Tenax Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Almenoff June Sherie | NC | D | | P.am | 15 | 7.50 | 0 | 2 | New | 2 | I | | | | | | | | | | | | | | |
11/20/25 18:13 | 11/18/25 | JAZZ | Jazz Pharmaceuticals Plc | L2 | Health | Drug | Pharmaceutical Preparations | Carr Patricia | L2 | O | SVP,Chie | S.d | -968 | 182.07 | 0 | -5 | -43 | 7 | D | | | | | | | | | | | | | | |
11/20/25 18:13 | 11/18/25 | JAZZ | Jazz Pharmaceuticals Plc | L2 | Health | Drug | Pharmaceutical Preparations | Carr Patricia | L2 | O | SVP,Chie | M.d | 715 | 136.18 | 0 | 5 | 298 | 7 | D | | | | | | | | | | | | | | |
11/20/25 18:10 | 11/20/25 | OPK | Opko Health, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Frost Phillip Md Et Al | FL | DOT | CEO,CB | P | 771 | 1.33 | 0 | 580 | 0 | 249,823 | I | | | | | | | | | | | | | | |
11/20/25 17:54 | 11/18/25 | JAZZ | Jazz Pharmaceuticals Plc | L2 | Health | Drug | Pharmaceutical Preparations | Winningham Rick E | L2 | D | | S | -995 | 180.86 | 0 | -6 | -38 | 9 | D | | | | | | | | | | | | | | |
11/20/25 17:52 | 11/18/25 | HOWL | Werewolf Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Evnin Luke | MA | D | | S.m | -95 | 0.9239 | 0 | -103 | -3 | 3,413 | I | | | | | | | | | | | | | | |
11/20/25 17:51 | 11/18/25 | HOWL | Werewolf Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Mpm Bioventures 2014, L.P. | MA | T | | S.m | -148 | 0.9239 | 0 | -160 | -3 | 5,321 | I | | | | | | | | | | | | | | |
11/20/25 17:50 | 11/18/25 | HOWL | Werewolf Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Gadicke Ansbert | MA | T | | S.m | -148 | 0.9239 | 0 | -160 | -3 | 5,321 | I | | | | | | | | | | | | | | |
11/20/25 17:39 | 11/19/25 | SAVA | Cassava Sciences Inc | DE | Health | Drug | Pharmaceutical Preparations | Barry Richard | TX | DO | P,CEO | P | 202 | 2.75 | 0 | 73 | 10 | 788 | I | | | | | | | | | | | | | | |
11/20/25 17:12 | 11/18/25 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Wender Joseph H | CA | D | | M.d | 391 | 24.42 | 0 | 16 | 25 | 80 | D | | | | | | | | | | | | | | |
11/20/25 17:12 | 11/19/25 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Herman Joan E | CA | D | | M.d | 2,525 | 57.40 | 0 | 44 | 999% | 46 | D | | | | | | | | | | | | | | |
11/20/25 17:12 | 11/19/25 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Herman Joan E | CA | D | | S.d | -3,174 | 72.13 | 0 | -44 | -49 | 46 | D | | | | | | | | | | | | | | |