Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	Title	T	TVal	Price	Qty	oc	Own	H
12/23/25 21:42	12/19/25	OLMA	Olema Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Clark Ian T	CA	D		M.d	1,220	4.61	265		0	D
12/23/25 21:42	12/19/25	OLMA	Olema Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Clark Ian T	CA	D		S.d	-7,873	29.73	-265	-100	0	D
12/23/25 21:41	12/19/25	OLMA	Olema Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Myles David C.	CA	O	CH. DISC	S	-1,554	30.46	-51	-7	711	D
12/23/25 21:40	12/19/25	OLMA	Olema Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Zojwalla Naseem	CA	O	Chief Me	M.dm	1,664	11.89	140		4	D
12/23/25 21:40	12/19/25	OLMA	Olema Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Zojwalla Naseem	CA	O	Chief Me	S.dm	-7,530	27.94	-270	-98	4	D
12/23/25 20:48	12/23/25	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Firestone Karen	MA	D		P	101	12.45	8	15	63	D
12/23/25 20:09	12/22/25	OKUR	Onkure Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Saccomano Nicholas A	CO	DO	P,CEO	S	0	2.97	0	-1	7	D
12/23/25 20:08	12/22/25	OKUR	Onkure Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Leverone Jason A.	CO	O	CFO	S	-1	2.97	0	-2	16	D
12/23/25 18:52	12/22/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ramasastry Saira	CA	D		M.d	118	23.51	5		0	D
12/23/25 18:52	12/22/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ramasastry Saira	CA	D		S.d	-400	80.00	-5	-100	0	D
12/23/25 18:50	12/19/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Grey Michael G	CA	D		M.d	147	2.94	50	22	280	D
12/23/25 18:50	12/19/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Grey Michael G	CA	D		S.d	-3,900	78.00	-50	-15	280	D
12/23/25 18:47	12/22/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hohl Benjamin	CO	O	CFO	M.d	32	2.48	13	57	36	D
12/23/25 18:45	12/19/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lyssikatos Joseph P	CO	O	CHIEF SC	S	-84	16.84	-5	-1	898	I
12/23/25 18:01	12/19/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Waddill William D.	CA	D		S	-566	67.65	-8	-13	57	D
12/23/25 18:01	12/19/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Vakiener Victoria	CA	D		S	-679	67.68	-10	-22	36	D
12/23/25 18:01	12/19/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Anzalone Christopher Richard	CA	DO	CEO	S.m	-1,771	68.04	-26	-1	3,806	D
12/23/25 18:01	12/19/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Olukotun Adeoye Y	CA	D		S	-677	67.66	-10	-23	34	D
12/23/25 17:00	12/19/25	PHAT	Phathom Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Parikh Asit	NJ	D		M.d	90	10.30	9	8	122	D
12/23/25 16:41	12/22/25	IMNM	Immunome Inc.	DE	Health	Drug	Pharmaceutical Preparations	Barchas Isaac	WA	D		S	-8,330	21.74	-383	-8	4,166	I
12/23/25 16:37	12/19/25	CLNN	Clene Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ugwumba Chidozie	AR	T		S.m	-65	6.49	-10	-3	383	I
12/23/25 16:33	12/23/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Malcolm Jan	MD	D		S	-26	512.12	0	-11	0	D
12/23/25 16:33	12/22/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Sullivan Louis W	MD	D		M.d	1,219	204.93	6		3	I
12/23/25 16:33	12/22/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Sullivan Louis W	MD	D		S.d	-3,047	512.14	-6	-65	3	I
12/23/25 16:31	12/22/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pelish Henry E.	MA	O	Chief Sc	M.d	5	1.08	5	8	71	D
12/23/25 16:30	12/22/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Balcom Alexandra	MA	O	CFO	M.d	37	1.08	35	63	89	D
12/23/25 16:30	12/23/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Ware J. Anthony	CA	D		S	-193	49.58	-4	-29	10	D
12/23/25 16:30	12/19/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Porter James Richard	MA	DO	P,CEO	M.d	37	0.6500	57	23	306	D
12/23/25 16:30	12/19/25	ALZN	Alzamend Neuro, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Horne William B.	GA	D		S	-7	2.12	-3	-100	0	D
12/23/25 16:28	12/22/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Lizzul Paul F.	CA	O	Chief Me	M.d	28	18.50	2	6	27	D
12/23/25 16:28	12/22/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Lizzul Paul F.	CA	O	Chief Me	S.d	-75	50.00	-2	-5	27	D
12/23/25 16:28	12/22/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Mulroy Dennis	CA	O	CFO	M.d	202	20.16	10		9	D
12/23/25 16:28	12/22/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Mulroy Dennis	CA	O	CFO	S.d	-500	50.00	-10	-52	9	D
12/23/25 16:27	12/22/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Loumeau Eric J	CA	O	GC	M.d	140	14.02	10		9	D
12/23/25 16:27	12/22/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Loumeau Eric J	CA	O	GC	S.d	-510	51.00	-10	-53	9	D
12/23/25 16:26	12/22/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Blum Robert I	CA	DO	P,CEO	M.d	475	6.67	71	22	395	D
12/23/25 16:24	12/23/25	EQ	Equillium, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Zedelmayer Christine	CA	O	SVP,COO	M.d	79	0.7850	100		91	D
12/23/25 16:24	12/23/25	EQ	Equillium, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Zedelmayer Christine	CA	O	SVP,COO	S.d	-150	1.50	-100	-52	91	D
12/23/25 16:16	12/19/25	FOLD	Amicus Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Clark David Michael	NJ	O	Chief Pe	S	-363	14.17	-26	-9	246	D
12/23/25 16:13	12/22/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Wierenga Wendell	CA	D		M.d	152	7.61	20	161	32	D
12/23/25 16:13	12/22/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Wierenga Wendell	CA	D		S.d	-1,323	66.14	-20	-38	32	D
12/23/25 16:10	12/23/25	ALT	Altimmune, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gill John	MD	D		P	51	4.10	13	New	13	D
12/23/25 16:02	12/22/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hyep Ivan	MA	O	CFO	M.d	35	3.79	9	7	145	D
12/23/25 16:02	12/22/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hyep Ivan	MA	O	CFO	S.d	-168	18.31	-9	-6	145	D
12/23/25 16:02	12/19/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	Desjarlais John R	CA	O	SVP,CSO	M.dm	997	12.51	80	49	243	D
12/23/25 16:02	12/19/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	Desjarlais John R	CA	O	SVP,CSO	S.d	-1,153	15.72	-73	-23	243	D
12/23/25 16:01	12/19/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	Dahiyat Bassil I	CA	DO	P,CEO	M.dm	1,564	12.51	125	35	477	D
12/23/25 16:01	12/19/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	Dahiyat Bassil I	CA	DO	P,CEO	S.d	-1,797	15.71	-114	-19	477	D
12/23/25 14:55	12/19/25	CAPR	Capricor Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dunbar George W Jr	CA	D		M.d	4	1.39	3	27	14	D
12/23/25 14:04	12/22/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	Moreadith Randall	AL	O	Chief Sc	M.d	0	0.0600	6		0	D
12/23/25 14:04	12/22/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	Moreadith Randall	AL	O	Chief Sc	S.d	-15	2.67	-6	-100	0	D
12/23/25 13:21	12/23/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Freeman Kevin D	GA	D		P.a	20	3.55	6	4	153	D
12/23/25 13:19	12/23/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Freeman Kevin D	GA	D		P.a	20	3.55	6	4	137	D
12/23/25 13:17	12/23/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Eldred Kary	GA	D		P	3	3.73	1	1	70	D
12/23/25 11:29	12/23/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Freeman Kevin D	GA	D		P	20	3.55	6	4	137	D
12/23/25 11:28	12/23/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Eldred Kary	GA	D		P	3	3.73	1	1	70	D
12/23/25 08:18	12/22/25	MAIA	Maia Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Smith Stan	IL	D		P.d	70	1.22	57	4	1,435	I
12/23/25 08:16	12/22/25	MAIA	Maia Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chaouki Steven M	IL	D		P.d	50	1.22	41	37	152	D
12/23/25 08:14	12/22/25	MAIA	Maia Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Louie Ngar Yee	IL	D		P.d	100	1.22	82	7	1,249	D
12/22/25 20:48	12/22/25	PGEN	Precigen, Inc.	VA	Health	Drug	Pharmaceutical Preparations	Kirk Randal J	VA	DT		S	-7,942	4.18	-1,900	-2	122,046	I
12/22/25 19:45	12/18/25	BNTC	Benitec Biopharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	Suvretta Capital Management, LLC	NY	DT		P.m	539	11.68	46	3	1,827	I
12/22/25 17:52	12/22/25	ZYME	Zymeworks Inc.	DE	Health	Drug	Pharmaceutical Preparations	Galbraith Kenneth	DE	DO	Chair,CE	M.d	0	0.00	100	301	133	D
12/22/25 17:52	12/22/25	ZYME	Zymeworks Inc.	DE	Health	Drug	Pharmaceutical Preparations	Galbraith Kenneth	DE	DO	Chair,CE	S.d	-1,284	27.02	-48	-26	133	D
12/22/25 17:15	12/18/25	MRUS	Merus N.V.	P7	Health	Drug	Pharmaceutical Preparations	Genmab A/S	G7	T		P.m	27,009	97.00	278	0	72,013	I
12/22/25 16:15	12/18/25	LITS	Lite Strategy, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Schornstein Alexander	2M	T		S	-946	1.37	-691	-16	3,675	D
12/22/25 16:10	12/22/25	ALT	Altimmune, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Durso Jerome Benedict	MD	D		P	52	4.13	13	New	13	D
12/22/25 16:09	12/19/25	RPRX	Royalty Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Urist Marshall	NY	O	EVP,Rese	S	-768	38.38	-20	-12	146	I
12/22/25 16:04	12/19/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mottola Frank	MD	O	SVP,Chie	M.d	577	28.83	20		15	D
12/22/25 16:04	12/19/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mottola Frank	MD	O	SVP,Chie	S.d	-1,008	50.41	-20	-56	15	D
12/22/25 16:00	12/19/25	LITS	Lite Strategy, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Flynn James P	CA	D		P	98	1.40	70	233	100	D
12/22/25 08:15	12/18/25	HYPD	Hyperion Defi, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Strahlman Ellen R	CA	D		P	121	3.14	38	29	171	M
12/22/25 07:38	12/19/25	IMNM	Immunome Inc.	DE	Health	Drug	Pharmaceutical Preparations	Siegall Clay B	WA	DO	P,CEO	P	149	20.48	7	1	661	D
12/22/25 07:32	12/19/25	IMNM	Immunome Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tsai Philip	WA	O	Chief Te	P	205	20.49	10	30	43	D
12/22/25 07:07	12/19/25	EVMN	Evommune, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hopfner Robert Lorne	CA	DT		P	17	17.35	1	0	3,372	I
12/22/25 07:00	12/18/25	RNXT	Renovorx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bagai Shaun	CA	DO	CEO	P	5	0.9013	5	1	340	D
12/19/25 21:30	12/18/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	Todisco Joseph	NJ	DO	CEO	M.d	133	4.43	30	6	509	D
12/19/25 21:30	12/18/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	Todisco Joseph	NJ	DO	CEO	S.d	-360	12.00	-30	-6	509	D
12/19/25 21:04	12/17/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Sukhatme Mayukh	X0	DO	P,CIO	M.d	755	12.68	60	0	18,837	D
12/19/25 21:04	12/17/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Sukhatme Mayukh	X0	DO	P,CIO	S.d	-620	23.09	-27	0	18,837	D
12/19/25 21:00	12/19/25	TYRA	Tyra Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	More Robert J	CA	D		S	-250	25.00	-10	0	3,823	I
12/19/25 20:00	12/17/25	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	Castagna Michael	CT	DO	CEO	M.d	299	4.55	66	3	2,505	D
12/19/25 20:00	12/17/25	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	Castagna Michael	CT	DO	CEO	S.d	-395	6.01	-66	-3	2,505	D
12/19/25 19:29	12/17/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D		S.m	-83	44.49	-2	0	3,595	I
12/19/25 19:24	12/17/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Thompson Peter A.	MA	D		S.m	-83	44.49	-2	0	3,595	I
12/19/25 19:21	12/17/25	HYPD	Hyperion Defi, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Walters Happy David	CA	D		P	187	3.02	62	124	112	D
12/19/25 18:56	12/17/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Anzalone Christopher Richard	CA	DO	CEO	S	-5,443	64.04	-85	-2	3,832	D
12/19/25 18:16	12/19/25	IRON	Disc Medicine, Inc.		Health	Drug	Pharmaceutical Preparations	Quisel John D	MA	DO	CEO	M.d	12	1.01	12	7	184	D
12/19/25 17:58	12/17/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kunkel Lori Anne	CO	D		M.d	18	1.12	16	35	62	D
12/19/25 17:38	12/19/25	ORKA	Oruka Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Goncalves Joana	CA	O	Chief Me	M.d	51	7.32	7		2	D
12/19/25 17:38	12/19/25	ORKA	Oruka Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Goncalves Joana	CA	O	Chief Me	S.d	-214	30.61	-7	-82	2	D
12/19/25 17:24	12/17/25	RPRX	Royalty Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Lloyd George W.	NY	O	EVP,Inve	S.m	-4,240	38.55	-110	-12	780	I
12/19/25 17:17	12/19/25	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	Johnson John	IL	D		S	-977	7.22	-135	-16	698	D
12/19/25 17:00	12/19/25	SVRA	Savara Inc	DE	Health	Drug	Pharmaceutical Preparations	Ramsay David A	PA	D		S	-121	6.06	-20	-1	2,534	D
12/19/25 17:00	12/17/25	ADTX	Aditxt, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Brady Brian Michael	CA	D		S	0	1.75	0	-25	0	D
12/19/25 16:47	12/18/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Davis Krista	MN	O	SVP,CHRO	S	-134	82.40	-2	-3	59	D
12/19/25 16:31	12/18/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Thompson Tommy G	MD	D		M.d	93	101.80	1	4	22	D
12/19/25 16:31	12/18/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Thompson Tommy G	MD	D		S.d	-456	500.59	-1	-4	22	D
12/19/25 16:30	12/17/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	M.dm	1,203	120.26	10	2	639	D
12/19/25 16:30	12/17/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	S.dm	-5,054	505.38	-10	-2	639	D
12/19/25 16:30	12/18/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Burrows Francis	CA	O	Chief Sc	M.d	168	4.80	35		34	D
12/19/25 16:30	12/18/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Burrows Francis	CA	O	Chief Sc	S.d	-232	9.78	-24	-41	34	D
12/19/25 16:15	12/18/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ramasastry Saira	CA	D		M.d	47	23.51	2		0	D
12/19/25 16:15	12/18/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ramasastry Saira	CA	D		S.d	-139	69.73	-2	-100	0	D
12/19/25 16:15	12/17/25	VTYX	Ventyx Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mohan Raju	CA	DO	CEO,P	M.d	0	0.00	117	5	2,373	D
12/19/25 16:15	12/18/25	VTYX	Ventyx Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mohan Raju	CA	DO	CEO,P	S.d	-365	7.72	-47	-2	2,373	D
12/19/25 16:15	12/17/25	VTYX	Ventyx Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Nuss John	CA	O	Chief Sc	M.d	0	0.00	35	8	489	D
12/19/25 16:15	12/18/25	VTYX	Ventyx Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Nuss John	CA	O	Chief Sc	S.d	-98	7.72	-13	-3	489	D
12/19/25 16:12	12/18/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Lewis William	NJ	DO	Chair,CE	M.d	267	24.94	11	2	588	D
12/19/25 16:12	12/18/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Lewis William	NJ	DO	Chair,CE	S.d	-1,786	166.97	-11	-2	588	D
12/19/25 16:08	12/17/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Lewis Joel	GA	DO	P,CEO	M.d	22	2.86	8	1	835	D
12/19/25 16:08	12/17/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Lewis Joel	GA	DO	P,CEO	S.d	-55	7.06	-8	-1	835	D
12/19/25 16:06	12/17/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Jamil Khurram	GA	O	Chief Me	S.d	-137	7.04	-19	-100	0	D
12/19/25 16:06	12/17/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Jamil Khurram	GA	O	Chief Me	M.d	35	2.37	15		0	D
12/19/25 16:05	12/18/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bhatt Padmanabh P.	MD	O	SVP of I	M.d	0	0.00	2	12	15	D
12/19/25 16:05	12/18/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bhatt Padmanabh P.	MD	O	SVP of I	S.d	-32	44.44	-1	-5	15	D
12/19/25 16:05	12/17/25	SLGL	Sol-Gel Technologies Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T		P	110	40.37	3	1	385	I
12/19/25 16:05	12/17/25	PVLA	Palvella Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Goin Kathleen	PA	O	COO	M.d	35	8.11	4		0	D
12/19/25 16:05	12/17/25	PVLA	Palvella Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Goin Kathleen	PA	O	COO	S.d	-415	96.47	-4	-100	0	D
12/19/25 16:05	12/17/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Shlevin Harold H.	GA	D		M.d	40	1.98	20		7	D
12/19/25 16:05	12/17/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Shlevin Harold H.	GA	D		S.d	-172	7.04	-24	-79	7	D
12/19/25 15:43	12/18/25	MNPR	Monopar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	Klausner Arthur J	IL	D		S	-344	67.15	-5	-37	9	D
12/19/25 11:00	12/17/25	HYPD	Hyperion Defi, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Geltzeiler Michael S	CA	D		P	90	3.01	30	52	88	D
12/19/25 07:00	12/17/25	RNXT	Renovorx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bagai Shaun	CA	DO	CEO	P	4	0.8524	5	2	335	D
12/19/25 06:05	12/18/25	GLSI	Greenwich Lifesciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Patel Snehal	TX	DOT	CEO,CFO	P	52	12.62	4	0	5,592	D
12/18/25 20:05	12/16/25	SRPT	Sarepta Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Estepan Ian Michael	MA	O	COO	S	-294	22.31	-13	-6	193	D
12/18/25 19:54	12/16/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Gold Daniel Allen	X0	D		S.m	-39,065	23.05	-1,695	-9	16,353	I
12/18/25 19:52	12/16/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Manchester Keith S	X0	D		S.m	-39,065	23.05	-1,695	-9	16,353	I
12/18/25 19:41	12/16/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Qvt Financial LP	NY	H	Director	S.m	-39,065	23.05	-1,695	-9	16,353	I
12/18/25 18:54	12/18/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Struthers Richard Scott	CA	DO	P,CEO	M.d	586	13.09	45	3	1,343	D
12/18/25 18:14	12/17/25	IRON	Disc Medicine, Inc.		Health	Drug	Pharmaceutical Preparations	Bitterman Kevin	MA	D		S	-69	91.47	-1	-5	14	I
12/18/25 18:08	12/18/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ring Christine	CA	O	GC	M.d	7	1.86	4	8	51	D
12/18/25 18:08	12/18/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ring Christine	CA	O	GC	S.d	-67	17.90	-4	-7	51	D
12/18/25 18:02	12/16/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mazumdar Claire	MA	DO	CEO	M.d	161	5.45	30	10	339	D
12/18/25 17:54	12/16/25	MRUS	Merus N.V.	P7	Health	Drug	Pharmaceutical Preparations	Genmab A/S	G7	T		P.m	26,340	97.00	272	0	71,735	I
12/18/25 17:35	12/16/25	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tang Carolyn C.	CA	O	GC	S.m	-318	22.01	-14	-10	125	D
12/18/25 17:35	12/16/25	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Markus Richard	CA	O	Chief Me	S.m	-210	22.01	-10	-13	66	D
12/18/25 17:35	12/16/25	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Azoy Alexander	CA	O	Chief Ac	S.m	-195	22.13	-9	-32	19	D
12/18/25 17:35	12/16/25	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Goeltz II Robert C.	CA	O	CFO	S.m	-279	22.01	-13	-15	74	D
12/18/25 17:35	12/16/25	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jarrett Jennifer	CA	O	COO	S.m	-467	22.01	-21	-10	193	D
12/18/25 17:35	12/16/25	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jaen Juan C.	CA	O	P	S.m	-467	22.01	-21	-2	1,300	D
12/18/25 17:35	12/16/25	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rosen Terry J	CA	DO	CEO	S.m	-1,204	22.01	-55	-2	2,195	D
12/18/25 17:23	12/17/25	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Zhou Rong	CA	O	SENIOR E	M.d	111	11.33	10	4	243	D
12/18/25 17:23	12/17/25	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Zhou Rong	CA	O	SENIOR E	S.d	-256	26.20	-10	-4	243	D
12/18/25 17:08	12/3/25	CLNN	Clene Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ugwumba Chidozie	AR	T		S.m	-1,726	6.69	-258	-40	393	I
12/18/25 17:03	12/18/25	IMNM	Immunome Inc.	DE	Health	Drug	Pharmaceutical Preparations	Siegall Clay B	WA	DO	P,CEO	P	1,000	21.50	47	6	853	D
12/18/25 16:47	12/16/25	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	Stuglik Brian M	MA	D		S	-5	9.14	-1	-1	101	D
12/18/25 16:46	12/16/25	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	Paterson Dan	MA	DO	P,CEO	S	-4	9.14	0	0	410	D
12/18/25 16:45	12/16/25	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	Gagnon Robert E.	MA	D		S	-3	9.14	0	-1	42	D
12/18/25 16:34	12/16/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Edmondson Frazor Titus III	MA	O	GC	S	-148	17.14	-9	-31	19	D
12/18/25 16:19	12/16/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Espinoza Octavio	FL	O	CFO	M.d	164	69.00	2	9	29	D
12/18/25 16:19	12/16/25	ORGO	Organogenesis Holdings Inc.	DE	Health	Drug	Pharmaceutical Preparations	Nussdorf Glenn H	NY	D		S	-1,027	5.14	-200	-2	11,749	D
12/18/25 16:14	12/16/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Loumeau Eric J	CA	O	GC	M.dm	362	16.07	23		9	D
12/18/25 16:14	12/16/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Loumeau Eric J	CA	O	GC	S.dm	-1,027	45.38	-23	-72	9	D
12/18/25 16:13	12/16/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Mulroy Dennis	CA	O	CFO	M.d	202	20.16	10		9	D
12/18/25 16:13	12/16/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Mulroy Dennis	CA	O	CFO	S.d	-705	44.85	-16	-63	9	D
12/18/25 16:11	12/17/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ceesay Abraham	MA	DO	CEO	S	-324	29.64	-11	-2	681	M
12/18/25 16:10	12/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Koenig Sheldon L.	MI	DO	P,CEO	S	-177	3.67	-48	-3	1,471	D
12/18/25 16:09	12/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Halladay Benjamin	MI	O	CFO	S	-27	3.67	-7	-2	468	D
12/18/25 16:09	12/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Looker Benjamin	MI	O	GC	S	-24	3.67	-7	-2	386	D
12/18/25 16:06	12/16/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Watson David O.	MA	O	GC	S	-122	24.49	-5	-3	164	D
12/18/25 16:04	12/16/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	Weiss Amir	L3	O	Chief Ac	S	-372	30.20	-12	-69	6	D
12/18/25 16:02	12/16/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	Mignone Roberto	L3	D		S	-2,341	30.24	-77	-14	473	I
12/18/25 15:13	12/16/25	APLT	Applied Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kanter Stacy J.	NY	D		S	-5	0.1120	-43	-40	65	D
12/18/25 10:34	12/16/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	10X Fund, L.P.	GA	T		S	-204	6.66	-31	-1	5,614	D
12/17/25 21:00	12/15/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Gline Matthew	X0	DO	CEO	M.d	47,062	12.16	3,871	29	17,287	D
12/17/25 21:00	12/15/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Gline Matthew	X0	DO	CEO	S.d	-37,723	21.68	-1,740	-9	17,287	D
12/17/25 19:56	12/16/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	Moreadith Randall	AL	O	Chief Sc	M.d	0	0.0600	3		0	D
12/17/25 19:56	12/16/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	Moreadith Randall	AL	O	Chief Sc	S.d	-10	2.96	-3	-100	0	D
12/17/25 19:21	12/15/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Multani Pratik S	CA	O	Chief Me	M.d	0	0.00	29	76	68	D
12/17/25 19:21	12/16/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Multani Pratik S	CA	O	Chief Me	S.d	-97	9.06	-11	-14	68	D
12/17/25 19:19	12/15/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Piscitelli Dominic	CA	O	CFO	M.d	0	0.00	29	76	68	D
12/17/25 19:19	12/16/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Piscitelli Dominic	CA	O	CFO	S.d	-97	9.06	-11	-14	68	D
12/17/25 19:18	12/15/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chacko Jacob	CA	DO	P,CEO	M.d	0	0.00	84	17	582	D
12/17/25 19:18	12/16/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chacko Jacob	CA	DO	P,CEO	S.d	-302	9.06	-33	-5	582	D
12/17/25 18:28	12/15/25	HOWL	Werewolf Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Evnin Luke	MA	D		S.m	-52	1.08	-48	-2	2,842	I
12/17/25 18:21	12/15/25	FOLD	Amicus Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Campbell Bradley L	NJ	DO	P,CEO	M.d	636	9.03	70	7	1,130	D
12/17/25 18:21	12/15/25	FOLD	Amicus Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Campbell Bradley L	NJ	DO	P,CEO	S.d	-846	10.86	-78	-6	1,130	D
12/17/25 18:19	12/15/25	FOLD	Amicus Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Clark David Michael	NJ	O	Chief Pe	S	-282	11.00	-26	-9	271	D
12/17/25 17:53	12/15/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Burnett Patrick	CA	O	See Rema	M.d	42	3.64	12	13	98	D
12/17/25 17:53	12/15/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Burnett Patrick	CA	O	See Rema	S.d	-333	28.94	-12	-10	98	D
12/17/25 17:43	12/16/25	RPRX	Royalty Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Urist Marshall	NY	O	EVP,Rese	S	-766	38.32	-20	-11	166	I
12/17/25 17:39	12/15/25	RPRX	Royalty Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Coyne Terrance P.	NY	O	EVP,CFO	S	-2,669	38.36	-70	-10	621	I
12/17/25 17:25	12/12/25	HRMY	Harmony Biosciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dayno Jeffrey M.	PA	DO	P,CEO	M.d	164	8.22	20		0	D
12/17/25 17:25	12/12/25	HRMY	Harmony Biosciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dayno Jeffrey M.	PA	DO	P,CEO	S.d	-1,040	40.11	-26	-100	0	D
12/17/25 16:58	12/15/25	SPRB	Spruce Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gharib Samir M.	CA	O	P,CFO	M.d	0	0.00	1	14	8	D
12/17/25 16:56	12/15/25	SPRB	Spruce Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Szwarcberg Javier B.	CA	DO	CEO	M.d	0	0.00	3	23	14	D
12/17/25 16:47	12/15/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Oyler John	V8	DO	CEO	S.m	-30,659	306.59	-100	0	51,196	D
12/17/25 16:38	12/15/25	KNSA	Kiniksa Pharmaceuticals International, Plc		Health	Drug	Pharmaceutical Preparations	Quart Barry D	X0	D		M.d	209	10.36	20		13	D
12/17/25 16:38	12/15/25	KNSA	Kiniksa Pharmaceuticals International, Plc		Health	Drug	Pharmaceutical Preparations	Quart Barry D	X0	D		S.d	-836	41.51	-20	-62	13	D
12/17/25 16:37	12/15/25	KNSA	Kiniksa Pharmaceuticals International, Plc		Health	Drug	Pharmaceutical Preparations	Tessari Eben	X0	O	COO	M.d	53	8.83	6	56	17	D
12/17/25 16:37	12/15/25	KNSA	Kiniksa Pharmaceuticals International, Plc		Health	Drug	Pharmaceutical Preparations	Tessari Eben	X0	O	COO	S.d	-501	41.56	-12	-42	17	D
12/17/25 16:23	12/15/25	LFVN	Lifevantage Corp		Health	Drug	Pharmaceutical Preparations	Lewis Darwin	UT	D		P	5	6.54	1	1	132	D
12/17/25 16:14	12/16/25	RZLT	Rezolute, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Hogenhuis Wladimir	CA	D		P	10	1.69	6	5	120	D
12/17/25 16:13	12/16/25	RZLT	Rezolute, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Roberts Brian Kenneth	CA	O	Chief Me	P	48	1.70	28	9	324	D
12/17/25 16:10	12/15/25	FULC	Fulcrum Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Oltmans Curtis Gale	MA	O	GC	S	-45	12.92	-3	-25	10	D
12/17/25 16:05	12/15/25	VERA	Vera Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Turner William D.	CA	O	Chief Re	M.d	155	15.53	10	80	23	D
12/17/25 16:05	12/15/25	VERA	Vera Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Turner William D.	CA	O	Chief Re	S.d	-501	50.08	-10	-31	23	D
12/17/25 07:00	12/16/25	RNXT	Renovorx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Agah Ramtin	CA	DO	Chief Me	P	10	0.8500	12	2	778	D
12/16/25 21:43	12/12/25	IRON	Disc Medicine, Inc.		Health	Drug	Pharmaceutical Preparations	Bitterman Kevin	MA	D		S.dm	-16,859	91.56	-184	-93	14	M
12/16/25 21:43	12/15/25	IRON	Disc Medicine, Inc.		Health	Drug	Pharmaceutical Preparations	Bitterman Kevin	MA	D		M.d	95	13.50	7	98	14	M

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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