Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	Title	T	TVal	Price	Qty	oc	Own	H
10/14/25 21:00	10/9/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Venker Eric	X0	O	P,Immuno	M.dm	1,992	15.85	126	9	1,505	D
10/14/25 21:00	10/9/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Venker Eric	X0	O	P,Immuno	S.dm	-2,047	16.29	-126	-8	1,505	D
10/14/25 20:11	10/10/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cheng Andrew	CA	DO	P,CEO	M.d	596	19.87	30	6	526	D
10/14/25 20:11	10/10/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cheng Andrew	CA	DO	P,CEO	S.d	-1,619	53.98	-30	-5	526	D
10/14/25 19:49	10/13/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Cook Meredith	MN	O	SVP,GC,S	S	-36	90.09	0	-1	76	D
10/14/25 18:00	10/10/25	BGMS	Bio Green Med Solution, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fitters Diversified Berhad	N8	T		S	-270	5.26	-51	-9	506	D
10/14/25 17:16	10/9/25	ZBIO	Zenas Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Nunn Jason Raleigh	PA	D		P	1,200	19.00	63	2	3,120	I
10/14/25 17:14	10/9/25	ZBIO	Zenas Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sr One Capital Management, LLC	PA	T		P	2,400	19.00	126	3	5,038	I
10/14/25 16:31	10/9/25	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	Bunn Paul A.	MA	D		S	-75	9.06	-8	-50	8	D
10/14/25 16:05	10/9/25	CVKD	Cadrenal Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Szot Matthew K	FL	O	CFO	S.m	-49	14.03	-3	-21	14	D
10/14/25 16:05	10/9/25	CVKD	Cadrenal Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pham Quang X	FL	DOT	CEO,CB	S.m	-51	14.09	-4	-1	399	D
10/14/25 16:01	10/10/25	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	Waddill William D.	CA	D		M.d	84	6.98	12		5	D
10/14/25 16:01	10/10/25	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	Waddill William D.	CA	D		S.d	-979	81.62	-12	-70	5	D
10/14/25 16:00	10/10/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	Lilly Endowment Inc	IN	T		S	-3,158	863.24	-4	0	94,533	D
10/14/25 13:16	10/13/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	Moreadith Randall	AL	O	Chief Sc	M.d	0	0.0600	4		0	D
10/14/25 13:16	10/13/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	Moreadith Randall	AL	O	Chief Sc	S.d	-22	5.20	-4	-100	0	D
10/14/25 12:15	10/13/25	RARE	Ultragenyx Pharmaceutical Inc.	DE	Health	Drug	Pharmaceutical Preparations	Horn Howard	CA	O	CFO	S	-250	31.51	-8	-7	98	D
10/14/25 08:59	10/9/25	ZBIO	Zenas Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Enright Patrick G	MA	D		P	2,250	19.19	117	5	2,619	M
10/10/25 20:06	10/8/25	ACET	Adicet Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T		P	5,000	1.00	5,000	207	7,421	I
10/10/25 19:48	10/8/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Graham G. Walmsley	CA	D		M.d	1,866	20.55	91	8	1,293	D
10/10/25 19:17	10/10/25	ZVRA	Zevra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McFarlane Neil F.	FL	DO	P,CEO	M.d	0	0.00	50	29	222	D
10/10/25 19:17	10/10/25	ZVRA	Zevra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McFarlane Neil F.	FL	DO	P,CEO	S.d	-211	10.82	-20	-8	222	D
10/10/25 18:45	10/8/25	LVTX	Lava Therapeutics Nv	P7	Health	Drug	Pharmaceutical Preparations	Cooperatieve Gilde Healthcare IV U.A.	P7	T		S.m	-198	1.56	-127	-2	5,294	D
10/10/25 18:17	9/12/25	BGMS	Bio Green Med Solution, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kua Khai Loon	N8	T		S.m	-267	5.65	-47	-12	338	D
10/10/25 18:16	10/8/25	BGMS	Bio Green Med Solution, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fitters Diversified Berhad	N8	T		S	-752	5.29	-142	-20	557	D
10/10/25 17:58	10/8/25	BYSI	Beyondspring Inc.		Health	Drug	Pharmaceutical Preparations	Decheng Capital China Life Sciences Usd Fund Iii, L.P.	CA	T		S.m	-25	1.78	-14	0	4,313	I
10/10/25 17:40	10/8/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kumar Neil	CA	DO	CEO	S.m	-4,383	54.79	-80	-1	5,697	I
10/10/25 17:33	10/9/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Khattar Jack A.	MD	DO	P,CEO	M.d	2,056	25.30	81	4	2,212	D
10/10/25 17:33	10/9/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Khattar Jack A.	MD	DO	P,CEO	S.d	-3,029	50.57	-60	-3	2,212	D
10/10/25 17:23	10/9/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Raben David	MA	O	Chief Me	M.d	83	3.79	22	163	35	D
10/10/25 17:23	10/9/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Raben David	MA	O	Chief Me	S.d	-406	18.45	-22	-38	35	D
10/10/25 17:22	10/9/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hyep Ivan	MA	O	CFO	M.d	24	3.79	6	5	145	D
10/10/25 17:22	10/9/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hyep Ivan	MA	O	CFO	S.d	-117	18.23	-6	-4	145	D
10/10/25 17:03	10/9/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	M.dm	962	120.26	8	1	644	D
10/10/25 17:03	10/9/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	S.dm	-3,574	446.81	-8	-1	644	D
10/10/25 16:56	10/8/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Lee Chan Henry	V8	O	SVP,GC	S.d	-3,739	350.40	-11	-5	223	D
10/10/25 16:56	10/8/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Lee Chan Henry	V8	O	SVP,GC	M.d	2,017	211.04	10	4	223	D
10/10/25 16:30	10/8/25	ALZN	Alzamend Neuro, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ault Milton C III	NV	D		S.dm	-295	2.42	-122	-85	21	I
10/10/25 16:21	10/9/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Newhall Charles W III	MD	D		S	-1,269	50.77	-25	-19	105	D
10/10/25 16:18	10/8/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Scadden David	MA	D		M.d	4	18.09	0	1	18	D
10/10/25 16:18	10/8/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Scadden David	MA	D		S.d	-8	41.00	0	-1	18	D
10/10/25 16:12	10/8/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kaye Edward M. Md	MA	D		M.d	15	0.6000	25	104	49	D
10/10/25 16:12	10/8/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kaye Edward M. Md	MA	D		S.d	-750	30.00	-25	-34	49	D
10/10/25 16:01	10/8/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	Anderman Todd	MA	O	GC	S	-137	12.34	-11	-11	88	D
10/10/25 16:00	10/9/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	Lilly Endowment Inc	IN	T		S	-9,038	852.49	-11	0	94,537	D
10/9/25 18:58	10/7/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rolph Timothy	CA	O	Chief Sc	M.d	354	28.35	13	8	167	D
10/9/25 18:58	10/7/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rolph Timothy	CA	O	Chief Sc	S.d	-576	46.08	-13	-7	167	D
10/9/25 18:58	10/8/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cheng Andrew	CA	DO	P,CEO	M.d	32	0.6150	52	11	526	D
10/9/25 17:51	10/7/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Guyer William	CA	O	Chief De	M.d	433	21.65	20		5	D
10/9/25 17:51	10/7/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Guyer William	CA	O	Chief De	S.d	-1,799	89.94	-20	-79	5	D
10/9/25 17:24	10/7/25	ZBIO	Zenas Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Moulder Leon O Jr	MA	DO	See Rema	P	770	20.85	37	2	1,975	I
10/9/25 17:21	10/7/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Patel Anish	CO	O	COO	S	-134	20.10	-7	-2	277	I
10/9/25 16:22	8/19/25	HOOK	Hookipa Pharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	Peters Malte	NY	DO	CEO	S	-21	0.8217	-25	-32	54	D
10/9/25 16:15	10/7/25	ZBIO	Zenas Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fairmount Funds Management LLC	PA	D		P	6,008	19.00	316	17	2,209	I
10/9/25 16:07	10/7/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bitterman Kevin	MA	D		S.m	-6,313	70.14	-90	-8	972	I
10/9/25 16:00	10/8/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	Lilly Endowment Inc	IN	T		S	-86,235	850.28	-101	0	94,548	D
10/9/25 15:37	9/13/24	ZBIO	Zenas Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lu Hongbo	MA	D		P.m	6,000	18.63	322	New	322	I
10/9/25 13:37	10/8/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Degnan Chris	NJ	O	CFO	M.d	0	0.00	4		2	D
10/9/25 13:37	10/8/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Degnan Chris	NJ	O	CFO	S.d	-37	16.85	-2	-49	2	D
10/9/25 09:01	10/8/25	MLTX	Moonlake Immunotherapeutics	E9	Health	Drug	Pharmaceutical Preparations	Bodenstedt Matthias	V8	O	CFO	P	99	9.09	11	2	628	D
10/8/25 21:08	10/6/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tabuteau Herriot	NY	DOT	CEO	M.dm	364	8.02	45	1	7,352	D
10/8/25 21:08	10/6/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tabuteau Herriot	NY	DOT	CEO	S.dm	-5,418	119.38	-45	-1	7,352	D
10/8/25 21:00	10/6/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Venker Eric	X0	O	P,Immuno	M.dm	5,956	8.95	665	79	1,505	D
10/8/25 21:00	10/6/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Venker Eric	X0	O	P,Immuno	S.dm	-10,782	16.21	-665	-31	1,505	D
10/8/25 20:55	10/6/25	SPRB	Spruce Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Parkman Healthcare Partners LLC	CT	T		P	5	17.91	0	32	1	I
10/8/25 20:55	10/6/25	SPRB	Spruce Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Parkman Healthcare Partners LLC	CT	T		S	-5	19.14	0	-20	1	I
10/8/25 19:48	10/1/25	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hunter Heather	MI	O	SVP,COO	S	-3	1.19	-3	-2	135	D
10/8/25 19:08	10/6/25	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jarrett Jennifer	CA	O	COO	M.dm	62	1.23	50	31	214	D
10/8/25 19:08	10/6/25	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jarrett Jennifer	CA	O	COO	S.dm	-750	14.92	-50	-19	214	D
10/8/25 18:37	10/6/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Swayze Eric	CA	O	EVP Rese	S	-473	69.02	-7	-18	31	D
10/8/25 18:37	10/6/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	O'Neil Patrick R.	CA	O	EVP CLO,	M.d	539	52.87	10	23	54	D
10/8/25 18:37	10/6/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	O'Neil Patrick R.	CA	O	EVP CLO,	S.d	-937	69.74	-13	-20	54	D
10/8/25 18:36	10/6/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Monia Brett P	CA	DO	CEO	S	-30	69.26	0	0	180	D
10/8/25 18:36	10/6/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Baroldi Joseph	CA	O	EVP,Chie	S	-113	69.37	-2	-5	33	D
10/8/25 17:37	10/6/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Piscitelli Dominic	CA	O	CFO	M.d	48	4.36	11	29	48	D
10/8/25 17:37	10/6/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Piscitelli Dominic	CA	O	CFO	S.d	-160	14.52	-11	-19	48	D
10/8/25 17:35	10/6/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chacko Jacob	CA	DO	P,CEO	S	-462	12.32	-37	-7	531	D
10/8/25 17:33	10/6/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hyep Ivan	MA	O	CFO	M.dm	115	3.79	30	26	145	D
10/8/25 17:33	10/6/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hyep Ivan	MA	O	CFO	S.dm	-553	18.21	-30	-17	145	D
10/8/25 17:33	10/6/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cohlhepp Ryan	MA	DO	P,COO	M.dm	121	3.79	32	19	203	D
10/8/25 17:33	10/6/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cohlhepp Ryan	MA	DO	P,COO	S.dm	-912	18.06	-51	-20	203	D
10/8/25 16:58	10/4/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Megna Michael R	X0	O	CHIEF AC	M.d	0	0.00	0	0	38	D
10/8/25 16:45	10/7/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Fisher Andrew	X0	O	GC	M.d	0	0.00	932		0	D
10/8/25 16:44	10/7/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Zaccardelli David	X0	DO	P,CEO	M.d	0	0.00	3,285		0	D
10/8/25 16:43	10/7/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Rickard Kathleen A.	X0	O	Chief Me	M.d	0	0.00	1,132		0	D
10/8/25 16:42	10/7/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Hahn Mark W	X0	O	CFO	M.d	0	0.00	3,285		0	D
10/8/25 16:41	10/7/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Austwick Michael	X0	D		M.d	0	0.00	72		0	D
10/8/25 16:40	10/7/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Ullman Anders	X0	D		M.d	0	0.00	72		0	D
10/8/25 16:38	10/7/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Shah Mahendra	X0	D		M.d	0	0.00	72		0	D
10/8/25 16:36	10/7/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Sinha Vikas	X0	D		M.d	0	0.00	72		0	D
10/8/25 16:35	10/7/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Deschamps Lisa	X0	D		M.d	0	0.00	72		0	D
10/8/25 16:34	10/7/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Ebsworth David R	X0	D		M.d	0	0.00	72		0	M
10/8/25 16:33	10/7/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Edwards Martin	X0	D		M.d	0	0.00	72		0	D
10/8/25 16:32	10/7/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Brady James Aloysius	X0	D		M.d	0	0.00	72		0	D
10/8/25 16:31	10/7/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	M.dm	962	120.26	8	1	644	D
10/8/25 16:31	10/7/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	S.dm	-3,611	451.35	-8	-1	644	D
10/8/25 16:31	10/7/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Cunningham Kenneth	X0	D		M.d	0	0.00	72		0	D
10/8/25 16:30	10/7/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Ackermann Christina	X0	D		M.d	0	0.00	72		0	D
10/8/25 16:16	10/7/25	CARM	Carisma Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Klichinsky Michael	PA	O	Chief Sc	M.d	6	0.1100	57		0	D
10/8/25 16:16	10/7/25	CARM	Carisma Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Klichinsky Michael	PA	O	Chief Sc	S.d	-14	0.2542	-57	-100	0	D
10/8/25 16:10	10/6/25	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	Taiwan Carbon Nano Technology Corp	F5	T		S	-25	3.59	-7	-1	1,037	D
10/8/25 16:00	10/7/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	Lilly Endowment Inc	IN	T		S	-22,722	848.01	-27	0	94,649	D
10/8/25 06:50	10/6/25	ALZN	Alzamend Neuro, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ault Milton C III	NV	D		S.dm	-344	2.47	-139	-63	82	I
10/7/25 20:22	10/6/25	CVKD	Cadrenal Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Szot Matthew K	FL	O	CFO	S	-1	13.99	0	-1	17	D
10/7/25 18:14	10/3/25	BYSI	Beyondspring Inc.		Health	Drug	Pharmaceutical Preparations	Decheng Capital China Life Sciences Usd Fund Iii, L.P.	CA	T		S.m	-36	1.78	-20	0	4,327	I
10/7/25 17:08	10/7/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Malik Fady Ibraham	CA	O	EVP Rese	M.d	21	10.60	2	1	141	D
10/7/25 17:08	10/7/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Malik Fady Ibraham	CA	O	EVP Rese	S.d	-121	60.56	-2	-1	141	D
10/7/25 17:00	10/3/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Booth Bruce	MA	D		S.m	-1,486	29.99	-50	-1	3,566	I
10/7/25 16:32	10/6/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Benkowitz Michael	MD	O	P,COO	M.d	3,131	139.13	23		3	I
10/7/25 16:32	10/6/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Benkowitz Michael	MD	O	P,COO	S.d	-10,130	450.24	-23	-89	3	I
10/7/25 16:26	10/3/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kaye Edward M. Md	MA	D		S	-1,065	25.09	-42	-46	49	D
10/7/25 16:26	10/3/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Allan Jonathan	MA	O	GC,Corp	M.d	92	9.15	10	546	12	D
10/7/25 16:26	10/3/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Allan Jonathan	MA	O	GC,Corp	S.d	-251	25.07	-10	-46	12	D
10/7/25 16:11	10/3/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mosbrooker Eric	CA	O	Chief Co	M.d	59	9.05	7	14	55	D
10/7/25 16:11	10/3/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mosbrooker Eric	CA	O	Chief Co	S.d	-298	45.38	-7	-11	55	D
10/7/25 16:00	10/6/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	Lilly Endowment Inc	IN	T		S	-137,042	850.22	-161	0	94,676	D
10/7/25 08:56	10/3/25	IMRX	Immuneering Corp	DE	Health	Drug	Pharmaceutical Preparations	Feinberg Peter	MA	D		P	50	6.67	8	1	1,141	D
10/7/25 07:05	10/4/25	PRLD	Prelude Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Huang Jane	DE	O	P,CMO	M.d	0	0.00	9	12	87	D
10/6/25 17:54	10/2/25	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	Taiwan Carbon Nano Technology Corp	F5	T		S	-7	3.59	-2	0	1,044	D
10/6/25 17:35	10/3/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	M.dm	962	120.26	8	1	644	D
10/6/25 17:35	10/3/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	S.dm	-3,584	447.95	-8	-1	644	D
10/6/25 17:22	10/2/25	BMY	Bristol Myers Squibb Co	DE	Health	Drug	Pharmaceutical Preparations	Gallman Cari	NJ	O	EVP,GC	M.d	0	0.00	5	70	11	D
10/6/25 17:13	10/2/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	Kaiser Peter	MA	O	Chief De	S	-106	11.03	-10	-5	194	D
10/6/25 17:10	10/2/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	Heier Jeffrey S.	MA	O	Chief Sc	S	-116	11.04	-11	-4	249	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Lee Kevin	X0	DO	CEO	S.m	-46	8.41	-5	-1	475	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Skynner Michael	X0	O	CTO	S.m	-15	8.41	-2	-2	118	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Milnes Alistair	X0	O	COO	S.m	-18	8.40	-2	-2	93	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Hannay Michael Charles Ferguson	X0	O	CHIEF PR	S.m	-6	8.40	-1	-1	53	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Young Alethia	X0	O	CFO	S	-4	8.51	0	-1	45	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Thompson Travis Alvin	X0	O	Chief Ac	S.m	-3	8.40	0	-1	31	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Swanton Robert Charles	X0	D		S	-1	8.55	0	-1	15	D
10/6/25 16:27	10/6/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Kaye Edward M. Md	CA	D		S	-405	60.00	-7	-41	10	D
10/6/25 16:00	10/3/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	Lilly Endowment Inc	IN	T		S	-161,220	837.93	-192	0	94,837	D
10/6/25 15:15	10/2/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Edwards Larry Todd	CA	O	See Rema	S	-90	20.04	-5	-2	179	D
10/6/25 09:12	10/3/25	PMN	Promis Neurosciences Inc.	Z4	Health	Drug	Pharmaceutical Preparations	Milbury Max A.	A6	H	Principa	P	15	0.4912	30	203	45	D
10/3/25 21:58	10/2/25	ELTP	Elite Pharmaceuticals Inc /Nv/	NJ	Health	Drug	Pharmaceutical Preparations	Plassche Douglas	NJ	O	EVP Oper	S	-499	0.6240	-800	-19	3,500	D
10/3/25 21:35	10/1/25	ALZN	Alzamend Neuro, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ault Milton C III	NV	D		S.dm	-297	2.41	-123	-85	21	I
10/3/25 21:27	10/1/25	JAZZ	Jazz Pharmaceuticals Plc	L2	Health	Drug	Pharmaceutical Preparations	Cozadd Bruce C	L2	D		S.m	-754	137.01	-6	-1	409	D
10/3/25 20:24	10/2/25	CVKD	Cadrenal Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pham Quang X	FL	DOT	CEO,CB	S	-7	14.13	-1	0	402	D
10/3/25 19:18	10/3/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Heyman Richard A.	CA	D		M.d	56	1.69	33	14	262	D
10/3/25 18:15	10/1/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hamilton James C	CA	O	Chief Me	S	-700	35.00	-20	-9	212	D
10/3/25 17:25	10/1/25	CARM	Carisma Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Klichinsky Michael	PA	O	Chief Sc	S.m	-124	0.2567	-484	-100	0	D
10/3/25 17:24	10/1/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Belanoff Joseph K	CA	DO	CEO	S	-3,403	85.08	-40	-1	2,781	I
10/3/25 17:17	10/1/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Lyon Joseph Douglas	CA	O	See Rema	M.d	68	13.56	5	95	10	D
10/3/25 17:17	10/1/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Lyon Joseph Douglas	CA	O	See Rema	S.d	-424	84.75	-5	-33	10	D
10/3/25 17:15	10/1/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Maduck Sean	CA	O	See Rema	M.d	159	7.95	20	20	118	D
10/3/25 17:15	10/1/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Maduck Sean	CA	O	See Rema	S.d	-1,701	85.06	-20	-15	118	D
10/3/25 17:14	10/2/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Poulton Jeffrey V.	MA	O	EVP,CFO	S	-1,727	452.05	-4	-7	54	D
10/3/25 17:14	10/2/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Greenstreet Yvonne	MA	DO	CEO	S	-4,034	452.05	-9	-12	66	D
10/3/25 17:14	10/2/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Tanguler Tolga	MA	O	EVP,Chie	S	-635	452.05	-1	-5	27	D
10/3/25 17:13	10/2/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Fitzgerald Kevin Joseph	MA	O	CSO,EVP,	S	-1,103	452.05	-2	-9	26	D
10/3/25 17:12	10/2/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Garg Pushkal	MA	O	EVP Chie	S.m	-2,692	451.76	-6	-22	21	D
10/3/25 17:02	10/1/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Watanabe Todd	CA	DO	See Rema	S.m	-885	19.66	-45	-4	1,080	D
10/3/25 17:01	10/1/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Welgus Howard G.	CA	D		M.d	16	1.68	10	11	100	D
10/3/25 17:01	10/1/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Welgus Howard G.	CA	D		S.d	-189	18.92	-10	-9	100	D
10/3/25 16:56	10/1/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Abate Kristin	MA	O	Chief Ac	S	-2	6.30	0	-3	10	D
10/3/25 16:45	10/1/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Kozarich John W	FL	D		S	-84	179.44	0	-1	45	D
10/3/25 16:41	10/1/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pizzuti Dana	CA	O	Chief Me	M.d	84	16.89	5	8	66	D
10/3/25 16:41	10/1/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pizzuti Dana	CA	O	Chief Me	S.d	-209	41.81	-5	-7	66	D
10/3/25 16:30	10/1/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Young Jonathan	CA	O	COO	M.d	264	21.10	13	5	257	D
10/3/25 16:30	10/1/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Young Jonathan	CA	O	COO	S.d	-597	47.76	-13	-5	257	D
10/3/25 16:28	10/1/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Balcom Alexandra	MA	O	CFO	M.d	176	8.82	20	48	62	D
10/3/25 16:28	10/1/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Balcom Alexandra	MA	O	CFO	S.d	-1,710	85.48	-20	-24	62	D
10/3/25 16:25	10/1/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ticho Barry	MA	O	Chief Me	S	-126	23.64	-5	-29	13	D
10/3/25 16:20	10/1/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Chen Yajing	MA	O	CFO	M.d	0	0.00	1	6	17	D
10/3/25 16:20	10/2/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Chen Yajing	MA	O	CFO	S.d	-16	34.25	0	-3	17	D
10/3/25 16:19	10/2/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Khattar Jack A.	MD	DO	P,CEO	M.d	0	0.00	39	2	2,191	D
10/3/25 16:18	10/2/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Khattar Jack A.	MD	DO	P,CEO	M.d	57	25.30	2	0	2,167	D
10/3/25 16:18	10/2/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Khattar Jack A.	MD	DO	P,CEO	S.d	-92	48.06	-2	0	2,167	D
10/3/25 16:07	10/2/25	VRTX	Vertex Pharmaceuticals Inc / Ma	MA	Health	Drug	Pharmaceutical Preparations	Biller Jonathan	MA	O	EVP,GC	S	-281	404.21	-1	-4	16	D
10/3/25 16:00	10/2/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	Lilly Endowment Inc	IN	T		S	-92,503	821.55	-113	0	95,029	D
10/3/25 13:18	10/2/25	SNGX	Soligenix, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Schaber Christopher J	NJ	DO	CB,CEO,P	P	20	1.32	15	999%	16	D
10/2/25 20:51	9/30/25	BYSI	Beyondspring Inc.		Health	Drug	Pharmaceutical Preparations	Decheng Capital China Life Sciences Usd Fund Iii, L.P.	CA	T		S.m	-14	1.80	-8	0	4,347	I
10/2/25 19:36	10/1/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Wender Joseph H	CA	D		S	-1,100	65.50	-17	-15	92	I
10/2/25 19:36	10/1/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Swayze Eric	CA	O	EVP Rese	M.dm	1,458	53.77	27	261	37	D
10/2/25 19:36	10/1/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Swayze Eric	CA	O	EVP Rese	S.dm	-1,794	66.16	-27	-42	37	D
10/2/25 19:35	10/2/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	O'Neil Patrick R.	CA	O	EVP CLO,	M.d	3,813	58.97	65		57	D
10/2/25 19:35	10/2/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	O'Neil Patrick R.	CA	O	EVP CLO,	S.d	-4,377	67.69	-65	-53	57	D
10/2/25 19:35	10/2/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Baroldi Joseph	CA	O	EVP,Chie	M.d	477	31.80	15	75	35	D
10/2/25 19:35	10/2/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Baroldi Joseph	CA	O	EVP,Chie	S.d	-1,020	68.01	-15	-30	35	D
10/2/25 19:24	10/1/25	TERN	Terns Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kuriakose Emil	CA	O	Chief Me	S	-7	7.85	-1	-2	52	D
10/2/25 19:18	9/30/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chacko Jacob	CA	DO	P,CEO	S.m	-1,054	12.04	-88	-13	569	D
10/2/25 17:04	10/1/25	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Petersen Floyd F.	CA	D		S	-14	27.20	-1	-1	76	D
10/2/25 16:56	10/1/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	Lilly Endowment Inc	IN	T		S	-177,290	821.47	-216	0	95,142	D
10/2/25 16:55	10/1/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	Lilly Endowment Inc	IN	T		S	-107,363	794.15	-135	0	95,358	D
10/2/25 16:51	10/1/25	MAIA	Maia Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Smith Stan	IL	D		P.d	25	1.30	19	1	1,324	I
10/2/25 16:47	9/30/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Baker Bros. Advisors LP	NY	H	Former 1	S.m	-1,057	1.45	-730	-63	425	I
10/2/25 16:44	9/30/25	SAVA	Cassava Sciences Inc	DE	Health	Drug	Pharmaceutical Preparations	Cook Robert Christopher	TX	O	COO,Lega	P	40	2.91	14	New	14	D
10/2/25 16:30	10/1/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	M.dm	962	120.26	8	1	644	D
10/2/25 16:30	10/1/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	S.dm	-3,441	430.17	-8	-1	644	D
10/2/25 16:30	10/2/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	M.d	1,490	135.42	11	43	37	D
10/2/25 16:30	10/2/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	S.d	-4,803	436.60	-11	-23	37	D
10/2/25 16:17	9/30/25	ANNX	Annexon, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Carson William H.	CA	D		P	13	3.05	4	11	42	D
10/2/25 16:15	9/30/25	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Klee Justin B.	MA	DO	Co-CEO	S	-431	14.38	-30	-1	3,325	D
10/2/25 16:15	9/30/25	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mazzariello Gina	MA	O	GC	S	-129	14.58	-9	-6	148	D
10/2/25 16:15	9/30/25	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Frates James M	MA	O	CFO	S	-155	14.65	-11	-3	307	D
10/2/25 16:15	9/30/25	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cohen Joshua B	MA	DO	Co-CEO	S	-429	14.35	-30	-1	3,325	D
10/2/25 16:15	9/30/25	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bedrosian Camille L	MA	O	Chief Me	S	-176	14.58	-12	-6	182	D
10/2/25 16:10	9/30/25	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	Taiwan Carbon Nano Technology Corp	F5	T		S.m	-9	3.48	-3	0	1,046	D
10/2/25 16:10	10/1/25	FBRX	Forte Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Riley Antony A	TX	O	CFO	M.d	0	0.00	0	1	32	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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