Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	Title	T	TVal	Price	Qty	oc	Own	H
7/25/25 19:06	7/23/25	IGMS	Igm Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tahir Misbah	CA	O	CFO	S	-11	1.27	-9	-5	170	D
7/25/25 19:03	7/23/25	IGMS	Igm Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Harler Mary Beth	CA	DO	CEO	S	-18	1.27	-15	-4	324	D
7/25/25 19:01	7/23/25	IGMS	Igm Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Decker Lisa Lynn	CA	O	CHIEF BU	S	-6	1.27	-4	-6	68	D
7/25/25 18:56	7/24/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	M.d	1,490	135.42	11	43	37	D
7/25/25 18:56	7/24/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	S.d	-3,345	304.11	-11	-23	37	D
7/25/25 18:54	7/23/25	DMAC	Diamedica Therapeutics Inc.	Z4	Health	Drug	Pharmaceutical Preparations	Stahlberg Jan	V7	T		P	5,400	3.50	1,543	30	6,764	I
7/25/25 18:24	7/25/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Weinhoff Gregory M	X0	O	Chief Bu	M.d	39	3.85	10	9	122	D
7/25/25 18:24	7/25/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Weinhoff Gregory M	X0	O	Chief Bu	S.d	-156	15.56	-10	-8	122	D
7/25/25 18:05	7/10/25	ELTP	Elite Pharmaceuticals Inc /Nv/	NJ	Health	Drug	Pharmaceutical Preparations	Kirkov Kirko	NJ	O	Chief Co	P	10	0.5890	16	New	16	D
7/25/25 17:49	7/23/25	DMAC	Diamedica Therapeutics Inc.	Z4	Health	Drug	Pharmaceutical Preparations	Von Koch Thomas	V7	T		P	10,000	3.50	2,857	52	8,384	I
7/25/25 17:22	7/23/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bitterman Kevin	MA	D		S.m	-2,616	61.03	-43	-4	1,106	I
7/25/25 16:35	7/23/25	DMAC	Diamedica Therapeutics Inc.	Z4	Health	Drug	Pharmaceutical Preparations	Jacinto Richard II	FL	T		P	1,400	3.50	400	9	4,959	I
7/25/25 16:00	7/24/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	Lilly Endowment Inc	IN	T		S	-225,419	805.07	-280	0	95,737	D
7/24/25 17:00	7/22/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Mandalam Ramkumar	TN	D		M.d	184	3.07	60	186	92	D
7/24/25 17:00	7/22/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Mandalam Ramkumar	TN	D		S.d	-295	7.24	-41	-31	92	D
7/23/25 21:10	7/21/25	HROW	Harrow, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Baum Mark L	TN	DOT	CEO	M.d	4,722	7.87	600	26	2,886	D
7/23/25 21:00	7/21/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Venker Eric	X0	O	P,Immuno	M.d	385	3.85	100	7	1,462	D
7/23/25 21:00	7/21/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Venker Eric	X0	O	P,Immuno	S.d	-1,152	11.52	-100	-6	1,462	D
7/23/25 18:57	7/21/25	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	Patel Dinesh V Ph D	CA	DO	P,CEO	S.m	-2,880	54.92	-52	-9	531	D
7/23/25 18:52	7/21/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lyssikatos Joseph P	CO	O	CHIEF SC	S	-279	22.29	-13	-1	953	I
7/23/25 18:09	7/22/25	HOOK	Hookipa Pharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	Peters Malte	NY	DO	CEO	S	-27	0.9200	-29	-27	80	D
7/23/25 18:07	7/22/25	HOOK	Hookipa Pharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	Coelho Mary Theresa	NY	DO	EVP,CFO	S	-13	0.9200	-14	-19	56	D
7/23/25 17:18	7/22/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Abate Kristin	MA	O	Chief Ac	S	-1	4.00	0	-2	9	D
7/23/25 17:00	7/22/25	MURA	Mural Oncology Plc	L2	Health	Drug	Pharmaceutical Preparations	Keson-Brookes Maiken	L2	O	See Rema	S	-6	2.48	-3	-4	69	D
7/23/25 16:35	7/21/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Bonstein Sara	NJ	O	CFO	M.d	1,467	30.63	48	187	74	D
7/23/25 16:35	7/21/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Bonstein Sara	NJ	O	CFO	S.d	-5,996	102.67	-58	-44	74	D
7/23/25 16:30	7/21/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Saggar Rajeev	NC	O	Chief Me	S	-37	14.54	-3	-1	269	D
7/23/25 16:16	7/21/25	SGMT	Sagimet Biosciences Inc.	DE	Health	Drug	Pharmaceutical Preparations	Happel David	CA	DO	P,CEO	S	-598	9.13	-65	-9	690	D
7/23/25 16:15	7/21/25	SGMT	Sagimet Biosciences Inc.	DE	Health	Drug	Pharmaceutical Preparations	Martins Eduardo Bruno	CA	O	Chief Me	S	-76	9.13	-8	-7	107	D
7/23/25 16:14	7/21/25	SGMT	Sagimet Biosciences Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rozek Elizabeth	CA	O	GC,CCO	S	-98	9.13	-11	-6	184	D
7/23/25 11:55	7/22/25	CALC	Calcimedica, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Roberts Eric W	CA	DOT	CHIEF BU	P	6	3.78	2	0	1,014	I
7/23/25 11:01	7/22/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Malik Fady Ibraham	CA	O	EVP Rese	M.d	21	10.60	2	1	141	D
7/23/25 11:01	7/22/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Malik Fady Ibraham	CA	O	EVP Rese	S.d	-75	37.47	-2	-1	141	D
7/22/25 20:26	7/22/25	BTAI	Bioxcel Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Steinhart Richard I	CT	O	CFO	M.d	0	0.00	1	11	6	D
7/22/25 20:25	7/22/25	BTAI	Bioxcel Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rodriguez Javier	CT	O	See Rema	M.d	0	0.00	1	10	7	D
7/22/25 19:51	7/18/25	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cesano Alessandra	CA	D		S	-91	3.37	-27	-39	42	D
7/22/25 17:08	7/18/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Taub Rebecca	PA	D		M.d	9	9.45	1	0	1,117	D
7/22/25 17:08	7/18/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Taub Rebecca	PA	D		S.d	-350	350.01	-1	0	1,117	D
7/22/25 17:06	7/18/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Friedman Paul A	PA	D		M.d	13	9.45	1	0	843	D
7/22/25 17:06	7/18/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Friedman Paul A	PA	D		S.d	-490	350.03	-1	0	843	D
7/22/25 17:00	7/18/25	MURA	Mural Oncology Plc	L2	Health	Drug	Pharmaceutical Preparations	Keson-Brookes Maiken	L2	O	See Rema	S	-5	2.48	-2	-3	71	D
7/22/25 16:54	7/18/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Wang Lai	V8	O	Global H	S	-210	300.00	-1	0	1,746	I
7/22/25 16:52	7/18/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Shelton Jerrell	TN	DO	P,CEO	M.d	125	5.00	25	3	987	D
7/22/25 16:44	7/18/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bitterman Kevin	MA	D		S	-41	61.13	-1	0	1,148	I
7/22/25 16:15	7/22/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Vazzano Joseph Walter	OH	O	CFO	S	-10	6.64	-2	0	478	D
7/22/25 15:24	7/22/25	ETST	Earth Science Tech, Inc.	FL	Health	Drug	Pharmaceutical Preparations	Saumat Giorgio R.	FL	DOT	CEO	P	10	0.2050	50	0	122,930	D
7/22/25 12:43	7/19/25	HRTX	Heron Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	Forbes William P	NC	O	EVP,Chie	M.d	0	0.00	4	3	139	D
7/22/25 12:23	7/19/25	HRTX	Heron Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	Duarte IRA	NC	O	EVP,CFO	M.d	0	0.00	4	3	153	D
7/22/25 12:15	7/21/25	CALC	Calcimedica, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Roberts Eric W	CA	DOT	CHIEF BU	P	5	3.37	2	0	1,012	I
7/22/25 11:55	7/19/25	HRTX	Heron Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	Collard Craig A	NC	DO	CEO	M.d	0	0.00	14	3	440	D
7/22/25 10:25	7/21/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	Moreadith Randall	AL	O	Chief Sc	M.d	0	0.0600	7		0	D
7/22/25 10:25	7/21/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	Moreadith Randall	AL	O	Chief Sc	S.d	-35	5.34	-7	-100	0	D
7/22/25 07:36	7/21/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Eldred Kary	GA	D		P	3	2.93	1	1	69	D
7/21/25 19:39	7/21/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Saha Saurabh	X0	DO	CEO	M.d	212	3.85	55	27	259	D
7/21/25 19:39	7/21/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Saha Saurabh	X0	DO	CEO	S.d	-876	15.92	-55	-18	259	D
7/21/25 19:21	7/17/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kintz Samuel	CO	DO	P,CEO	S	-282	22.52	-13	-1	940	I
7/21/25 19:14	7/17/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Maduck Sean	CA	O	See Rema	M.dm	24	5.05	5	4	117	D
7/21/25 19:14	7/17/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Maduck Sean	CA	O	See Rema	S.dm	-352	73.47	-5	-4	117	D
7/21/25 19:11	7/17/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Belanoff Joseph K	CA	DO	CEO	S	-45	73.69	-1	0	2,901	I
7/21/25 19:10	7/17/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Lyon Joseph Douglas	CA	O	See Rema	M.dm	55	13.56	4	68	10	D
7/21/25 19:10	7/17/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Lyon Joseph Douglas	CA	O	See Rema	S.dm	-300	73.47	-4	-29	10	D
7/21/25 19:10	7/17/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Guyer William	CA	O	Chief De	M.dm	106	21.65	5	802	5	D
7/21/25 19:10	7/17/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Guyer William	CA	O	Chief De	S.dm	-358	73.48	-5	-47	5	D
7/21/25 16:43	7/17/25	APVO	Aptevo Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Harsanyi Zsolt	WA	D		M.d	0	0.00	0	New	0	D
7/21/25 16:42	7/17/25	APVO	Aptevo Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kunz Barbara Lopez	WA	D		M.d	0	0.00	0	New	0	D
7/21/25 16:42	7/21/25	ETST	Earth Science Tech, Inc.	FL	Health	Drug	Pharmaceutical Preparations	Saumat Giorgio R.	FL	DOT	CEO	P	20	0.2000	100	0	122,880	D
7/21/25 16:41	7/17/25	APVO	Aptevo Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Abdun-Nabi Daniel	WA	D		M.d	0	0.00	0	New	0	D
7/21/25 16:40	7/17/25	APVO	Aptevo Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Grant Grady III	WA	D		M.d	0	0.00	0	New	0	D
7/21/25 16:39	7/17/25	APVO	Aptevo Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Niederhuber John	WA	D		M.d	0	0.00	0	New	0	D
7/21/25 16:38	7/17/25	APVO	Aptevo Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Taylor Daphne	WA	O	SVP,CFO	M.d	0	0.00	0	New	0	D
7/21/25 16:37	7/17/25	APVO	Aptevo Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kwon Soyoung	WA	O	SVP,GC,B	M.d	0	0.00	0	300	0	D
7/21/25 16:36	7/17/25	APVO	Aptevo Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	White Marvin L	WA	DO	P,CEO	M.d	0	0.00	0	500	0	D
7/21/25 16:35	7/17/25	APVO	Aptevo Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lamothe Jeffrey G.	WA	O	EVP,COO	M.d	0	0.00	0	500	0	D
7/21/25 16:15	7/17/25	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	Taiwan Carbon Nano Technology Corp	F5	T		S.m	-39	2.81	-14	-1	1,080	D
7/21/25 14:02	7/21/25	CALC	Calcimedica, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Leheny A. Rachel	CA	DOT	CEO	P	3	3.40	1	0	875	I
7/21/25 08:30	7/18/25	ANIX	Anixa Biosciences Inc	DE	Health	Drug	Pharmaceutical Preparations	Baskies Arnold M	CA	D		P	17	3.39	5	4	125	D
7/18/25 18:00	7/16/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yale Catriona	CA	O	Chief De	M.d	199	19.87	10	12	91	D
7/18/25 18:00	7/16/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yale Catriona	CA	O	Chief De	S.d	-529	52.95	-10	-10	91	D
7/18/25 16:51	7/17/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Franchi Jean M.	MA	O	CFO	S	-120	59.00	-2	-3	63	D
7/18/25 16:30	7/16/25	SNDX	Syndax Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Goldan Keith A.	NY	O	CFO	S	-12	9.29	-1	-1	92	D
7/18/25 16:30	7/16/25	SNDX	Syndax Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Metzger Michael A	NY	DO	CEO	S	-70	9.29	-8	-2	299	D
7/18/25 16:13	7/16/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Friedman Paul A	PA	D		M.dm	273	9.45	29	4	843	D
7/18/25 16:13	7/16/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Friedman Paul A	PA	D		S.dm	-10,199	353.19	-29	-3	843	D
7/18/25 16:12	7/17/25	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	Reed John C	NJ	O	EVP,Inno	S	-3,130	163.55	-19	-64	11	D
7/18/25 16:11	7/16/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Taub Rebecca	PA	D		M.dm	275	9.45	29	3	1,117	D
7/18/25 16:11	7/16/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Taub Rebecca	PA	D		S.dm	-10,278	353.19	-29	-3	1,117	D
7/18/25 16:07	7/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Looker Benjamin	MI	O	GC	S	-1	1.13	-1	0	400	D
7/18/25 16:05	7/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Halladay Benjamin	MI	O	CFO	S	0	1.12	0	0	474	D
7/18/25 16:05	7/17/25	MRUS	Merus N.V.	P7	Health	Drug	Pharmaceutical Preparations	Silverman Peter B.	P7	O	COO,GC	M.d	611	24.43	25		0	D
7/18/25 16:05	7/17/25	MRUS	Merus N.V.	P7	Health	Drug	Pharmaceutical Preparations	Silverman Peter B.	P7	O	COO,GC	S.d	-1,500	60.00	-25	-100	0	D
7/18/25 16:05	7/16/25	PHAT	Phathom Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Breedlove Robert Charles	NJ	O	Principa	S	-14	8.36	-2	-3	54	D
7/18/25 16:02	7/17/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Francois Cedric	MA	DO	CEO	M.d	39	4.31	9	0	1,871	D
7/18/25 16:02	7/17/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Francois Cedric	MA	DO	CEO	S.d	-399	20.21	-20	-1	1,871	D
7/18/25 16:00	7/16/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Watson David O.	MA	O	GC	S	-98	19.55	-5	-2	209	D
7/18/25 14:42	7/18/25	CALC	Calcimedica, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Wilson Robert N	CA	D		P	13	2.87	5	1	422	D
7/18/25 14:36	7/18/25	CALC	Calcimedica, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Roberts Eric W	CA	DOT	CHIEF BU	P	6	2.88	2	0	1,011	I
7/18/25 10:38	7/17/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Freeman Kevin D	GA	D		P	14	2.90	5	4	148	D
7/17/25 20:51	7/16/25	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	Binder Steven B.	CT	D		S	-297	3.94	-75	-8	831	D
7/17/25 20:46	7/16/25	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	Thomson David	CT	O	EVP Genl	S	-29	3.94	-7	-1	842	D
7/17/25 18:20	7/15/25	ETNB	89Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Le-Nguyen Quoc	CA	O	See Rema	S	-115	11.02	-10	-3	324	D
7/17/25 17:19	7/15/25	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	Kling Douglas F	P7	O	COO	M.dm	1,075	10.90	99		44	D
7/17/25 17:19	7/15/25	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	Kling Douglas F	P7	O	COO	S.dm	-2,097	21.26	-99	-69	44	D
7/17/25 16:59	7/15/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Loscalzo Joseph	CA	D		M.d	0	0.00	4	13	36	D
7/17/25 16:54	7/15/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Yang Michael J.	CA	D		M.d	0	0.00	4	211	6	D
7/17/25 16:54	7/15/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Wender Joseph H	CA	D		M.d	0	0.00	4	3	137	I
7/17/25 16:54	7/15/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Parshall B Lynne	CA	D		M.d	0	0.00	4	5	91	D
7/17/25 16:54	7/15/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Herman Joan E	CA	D		M.d	0	0.00	4	10	46	D
7/17/25 16:54	7/15/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Hayden Michael R	CA	D		M.d	0	0.00	4	8	56	D
7/17/25 16:53	7/15/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Diaz Allene M.	CA	D		M.d	0	0.00	4	26	20	D
7/17/25 16:53	7/15/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Berthelsen Spencer R	CA	D		M.d	0	0.00	4	3	156	D
7/17/25 16:32	7/15/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Balcom Alexandra	MA	O	CFO	M.dm	379	18.93	20	48	62	D
7/17/25 16:32	7/15/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Balcom Alexandra	MA	O	CFO	S.dm	-1,693	84.67	-20	-24	62	D
7/17/25 16:31	7/15/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Porter James Richard	MA	DO	P,CEO	M.d	511	18.93	27	12	249	D
7/17/25 16:31	7/15/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Porter James Richard	MA	DO	P,CEO	S.d	-2,221	82.27	-27	-10	249	D
7/17/25 16:15	7/15/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Hussain Iqbal J	X0	O	GC	M.d	35	5.84	6	6	111	D
7/17/25 16:15	7/15/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Hussain Iqbal J	X0	O	GC	S.d	-90	14.93	-6	-5	111	D
7/17/25 16:10	7/15/25	GBIO	Generation Bio Co.	DE	Health	Drug	Pharmaceutical Preparations	Howze Yalonda	MA	O	GC	M.d	0	0.00	3	19	21	D
7/17/25 16:10	7/15/25	GBIO	Generation Bio Co.	DE	Health	Drug	Pharmaceutical Preparations	Conway Kevin John	MA	O	CFO	M.d	0	0.00	1	3	18	D
7/17/25 16:10	7/15/25	GBIO	Generation Bio Co.	DE	Health	Drug	Pharmaceutical Preparations	Paone Antoinette	MA	O	COO	M.d	0	0.00	2	5	35	D
7/17/25 16:10	7/15/25	GBIO	Generation Bio Co.	DE	Health	Drug	Pharmaceutical Preparations	Samayoa Phillip	MA	O	CHIEF SC	M.d	0	0.00	1	1	141	D
7/17/25 16:10	7/15/25	GBIO	Generation Bio Co.	DE	Health	Drug	Pharmaceutical Preparations	McDonough Geoff	MA	DO	P,CEO	M.d	0	0.00	5	0	1,866	D
7/17/25 10:40	7/14/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	Moreadith Randall	AL	O	Chief Sc	M.d	0	0.0600	7		0	D
7/17/25 10:40	7/14/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	Moreadith Randall	AL	O	Chief Sc	S.d	-33	5.01	-7	-100	0	D
7/16/25 21:06	7/14/25	MNPR	Monopar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	Tsuchimoto Kim R	IL	D		S.d	-356	40.00	-9	-44	11	D
7/16/25 21:03	7/14/25	MNPR	Monopar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	Starr Christopher M	IL	D		S.d	-672	40.00	-17	-53	15	D
7/16/25 21:02	7/14/25	MNPR	Monopar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	Robinson Chandler	IL	DO	CEO	S.d	-672	40.00	-17	-2	896	D
7/16/25 18:01	7/14/25	TBPH	Theravance Biopharma, Inc.	E9	Health	Drug	Pharmaceutical Preparations	Farnum Rhonda	CA	O	SVP,COMM	S	-114	11.39	-10	-3	327	D
7/16/25 16:30	7/14/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Tessari Eben	X0	O	COO	M.d	57	8.83	7	15	49	D
7/16/25 16:30	7/14/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Tessari Eben	X0	O	COO	S.d	-543	28.72	-19	-28	49	D
7/16/25 16:20	7/14/25	ANNX	Annexon, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yednock Ted	CA	O	EVP,CHIE	S	-3	2.58	-1	-1	105	D
7/16/25 16:20	7/14/25	ANNX	Annexon, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lew Jennifer	CA	O	EVP,CFO	S	-3	2.58	-1	-1	122	D
7/16/25 16:20	7/14/25	ANNX	Annexon, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Overdorf Michael	CA	O	EVP,CHIE	S	-2	2.61	-1	-1	131	D
7/16/25 16:14	7/15/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bredt David	MA	O	Chief Sc	S	-119	14.00	-9	-2	435	D
7/16/25 16:11	7/14/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Francois Cedric	MA	DO	CEO	M.dm	284	4.31	66	4	1,882	D
7/16/25 16:11	7/14/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Francois Cedric	MA	DO	CEO	S.dm	-2,813	20.19	-139	-7	1,882	D
7/16/25 12:58	7/14/25	CALC	Calcimedica, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Roberts Eric W	CA	DOT	CHIEF BU	P	16	2.43	7	1	1,009	I
7/15/25 21:29	7/14/25	CALC	Calcimedica, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Leheny A. Rachel	CA	DOT	CEO	P	6	2.47	3	0	874	I
7/15/25 20:54	7/11/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Monia Brett P	CA	DO	CEO	S	-48	41.74	-1	-1	180	D
7/15/25 17:53	7/15/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Lewis William	NJ	DO	Chair,CE	M.d	74	10.85	7	1	588	I
7/15/25 17:53	7/15/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Lewis William	NJ	DO	Chair,CE	S.d	-699	102.38	-7	-1	588	I
7/15/25 17:52	7/11/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Smith Michael Alexander	NJ	O	GC	S.m	-168	99.80	-2	-2	66	D
7/15/25 17:38	7/14/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Blum Robert I	CA	DO	P,CEO	S	-191	38.15	-5	-1	397	D
7/15/25 17:11	7/14/25	DYN	Dyne Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cox John	MA	DO	CEO,P	P	911	9.11	100	57	274	D
7/15/25 17:02	7/11/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Congleton Jon	PA	DO	CEO	S	-230	14.51	-16	-2	846	D
7/15/25 17:01	7/11/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Levy Adam Scott	PA	O	CFO,Secr	S	-155	14.45	-11	-5	207	D
7/15/25 17:00	7/14/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rodman David Malcom	PA	O	Chief Me	M.d	7	1.08	6	7	98	D
7/15/25 17:00	7/14/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rodman David Malcom	PA	O	Chief Me	S.d	-166	14.59	-11	-10	98	D
7/15/25 16:36	7/11/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Schundler Russell	NC	O	GC	M.d	0	0.00	4	1	592	D
7/15/25 16:36	7/14/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Schundler Russell	NC	O	GC	S.d	-112	14.28	-8	-1	592	D
7/15/25 16:36	7/11/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Saggar Rajeev	NC	O	Chief Me	M.d	0	0.00	4	1	271	D
7/15/25 16:36	7/14/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Saggar Rajeev	NC	O	Chief Me	S.d	-76	14.28	-5	-2	271	D
7/15/25 16:35	7/11/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Moomaw Scott	NC	O	Chief Co	M.d	0	0.00	3	1	223	D
7/15/25 16:35	7/14/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Moomaw Scott	NC	O	Chief Co	S.d	-69	14.28	-5	-2	223	D
7/15/25 16:35	7/14/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Krepp Sarah	NC	O	Chief Hu	S	-38	14.28	-3	-2	142	D
7/15/25 16:34	7/11/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Kaseta Michael	NC	O	CFO,COO	M.d	0	0.00	6	1	406	D
7/15/25 16:34	7/14/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Kaseta Michael	NC	O	CFO,COO	S.d	-165	14.28	-12	-3	406	D
7/15/25 16:33	7/11/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Jeffs Roger	NC	DO	CEO	M.d	0	0.00	14	1	2,627	D
7/15/25 16:33	7/14/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Jeffs Roger	NC	DO	CEO	S.d	-289	14.28	-20	-1	2,627	D
7/15/25 16:33	7/11/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Jeffs Roger	NC	DO	CEO	M.d	0	0.00	14	1	2,627	D
7/15/25 16:33	7/14/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Jeffs Roger	NC	DO	CEO	S.d	-289	14.28	-20	-1	2,627	D
7/15/25 16:30	7/14/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Boyle Dana	NC	O	Chief Ac	S	-17	14.28	-1	-1	187	D
7/15/25 16:30	7/11/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Adair Jason	NC	O	Chief Bu	M.d	0	0.00	2	1	194	D
7/15/25 16:30	7/14/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Adair Jason	NC	O	Chief Bu	S.d	-37	14.28	-3	-1	194	D
7/15/25 16:05	7/10/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Scadden David	MA	D		M.d	25	18.09	1	9	18	D
7/15/25 16:05	7/10/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Scadden David	MA	D		S.d	-56	40.00	-1	-7	18	D
7/15/25 07:00	7/11/25	AVBP	Arrivent Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lachapelle Robin	PA	O	COO	M.d	25	2.28	11	2	530	D
7/15/25 06:03	7/11/25	ANIX	Anixa Biosciences Inc	DE	Health	Drug	Pharmaceutical Preparations	Titterton Lewis H Jr	CA	D		P	31	3.14	10	1	943	D
7/14/25 21:36	7/10/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Franchi Jean M.	MA	O	CFO	S	-115	57.50	-2	-3	66	D
7/14/25 17:07	7/10/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hohl Benjamin	CO	O	CFO	M.d	2	2.48	1	5	23	D
7/14/25 17:07	7/10/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hohl Benjamin	CO	O	CFO	S.d	-23	22.66	-1	-4	23	D
7/14/25 16:36	7/10/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Swisher Daniel N Jr	CA	D		M.d	31	14.08	2		0	D
7/14/25 16:36	7/10/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Swisher Daniel N Jr	CA	D		S.d	-156	71.08	-2	-100	0	D
7/14/25 16:30	7/10/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	M.d	1,490	135.42	11	43	37	D
7/14/25 16:30	7/10/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	S.d	-3,303	300.31	-11	-23	37	D
7/14/25 16:30	7/10/25	COGT	Cogent Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fairmount Funds Management LLC	PA	D		P	25,000	9.00	2,778	45	9,003	I
7/14/25 16:11	7/14/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Cook Meredith	MN	O	SVP,GC,S	S	-26	64.88	0	-1	79	D
7/14/25 16:02	7/10/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Burnett Patrick	CA	O	See Rema	M.dm	0	0.00	29	33	115	D
7/14/25 16:02	7/10/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Burnett Patrick	CA	O	See Rema	S.dm	-433	15.05	-29	-20	115	D
7/14/25 15:23	7/10/25	PRGO	Perrigo Co Plc	L2	Health	Drug	Pharmaceutical Preparations	Lockwood-Taylor Patrick	MI	DO	CEO	M.d	772	27.27	28	53	81	D
7/14/25 08:40	7/11/25	ANIX	Anixa Biosciences Inc	DE	Health	Drug	Pharmaceutical Preparations	Kumar Amit	CA	O	CEO	P	16	3.15	5	1	575	D
7/11/25 18:30	7/10/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cheng Andrew	CA	DO	P,CEO	S	-1,535	51.16	-30	-5	521	D
7/11/25 18:17	7/10/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Kozarich John W	FL	D		S	-117	125.00	-1	-2	46	D
7/11/25 17:50	6/2/25	CPIX	Cumberland Pharmaceuticals Inc		Health	Drug	Pharmaceutical Preparations	Young Caroline	TN	D		P.m	0	4.80	0	0	33	D
7/11/25 17:49	6/2/25	CPIX	Cumberland Pharmaceuticals Inc		Health	Drug	Pharmaceutical Preparations	Kazimi A J	TN	DOT	CB,CEO	P.m	1	4.80	0	0	5,699	D
7/11/25 17:48	6/2/25	CPIX	Cumberland Pharmaceuticals Inc		Health	Drug	Pharmaceutical Preparations	Jones James	TN	D		P.m	1	4.80	0	0	43	D
7/11/25 17:46	6/2/25	CPIX	Cumberland Pharmaceuticals Inc		Health	Drug	Pharmaceutical Preparations	Krogulski Kenneth	TN	D		P.m	5	4.83	1	0	287	D
7/11/25 17:27	7/9/25	TRDA	Entrada Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Parmar Kush	CA	DT		S	-203	7.50	-27	-1	4,256	I
7/11/25 17:25	7/9/25	TRDA	Entrada Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5Am Ventures V, L.P.	CA	T		S	-203	7.50	-27	-1	4,256	M
7/11/25 17:14	7/9/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Oyler John	V8	DO	CEO	S	-7,045	253.38	-28	0	53,868	D
7/11/25 16:59	7/9/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gheuens Sarah	MA	O	Chief Me	M.d	298	25.01	12	24	61	D
7/11/25 16:59	7/9/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gheuens Sarah	MA	O	Chief Me	S.d	-453	37.99	-12	-16	61	D
7/11/25 16:48	7/9/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Quisel John D	MA	DO	CEO	M.d	343	9.86	35	27	162	D
7/11/25 16:48	7/9/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Quisel John D	MA	DO	CEO	S.d	-1,926	55.33	-35	-18	162	D
7/11/25 16:31	7/9/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Smith Hunter C	MA	O	CFO	M.d	290	6.88	42	56	117	D
7/11/25 16:31	7/9/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Smith Hunter C	MA	O	CFO	S.d	-3,390	80.48	-42	-26	117	D
7/11/25 16:30	7/9/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Shulman Joseph	MA	O	Chief Te	M.d	54	6.80	8	999%	9	D
7/11/25 16:30	7/9/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Shulman Joseph	MA	O	Chief Te	S.d	-620	77.78	-8	-48	9	D
7/11/25 16:30	7/9/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	German Christopher Paul	MA	O	Corporat	M.d	78	27.29	3		1	D
7/11/25 16:30	7/9/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	German Christopher Paul	MA	O	Corporat	S.d	-308	80.75	-4	-81	1	D
7/11/25 16:30	7/9/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pelish Henry E.	MA	O	Chief Sc	S.dm	-614	80.31	-8	-11	61	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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