HLCS - Helicos Biosciences Corp - Insider Stock Trading

Filing Date	T Date	Ticker	Sector	Ind	Industry	Owner	oSt	Rel	Title	T	TVal	Price	Qty	oc	Own	H
10/5/09 17:04	9/18/09	HLCS	Health	Drug	Pharmaceutical Preparations	Afeyan Noubar	MA	DT		P.ad	0	0.00	243	2	12,193	I
9/22/09 19:51	9/18/09	HLCS	Health	Drug	Pharmaceutical Preparations	Flagship Ventures Fund 2004 L P	MA	DT		P.d	0	0.00	243	2	12,193	I
9/22/09 19:50	9/18/09	HLCS	Health	Drug	Pharmaceutical Preparations	Afeyan Noubar	MA	DT		P.d	0	0.00	243	2	12,193	I
9/22/09 17:44	9/18/09	HLCS	Health	Drug	Pharmaceutical Preparations	Lowy Ronald A	MA	DO	CEO	P.d	0	0.00	58	54	167	D
9/22/09 16:16	9/18/09	HLCS	Health	Drug	Pharmaceutical Preparations	Barrett Peter	MA	DT		P.d	0	0.00	243	2	11,851	I
9/22/09 16:16	9/18/09	HLCS	Health	Drug	Pharmaceutical Preparations	Atlas Venture Fund V LP	MA	DT		P.d	0	0.00	243	2	11,851	I
9/22/09 16:15	9/18/09	HLCS	Health	Drug	Pharmaceutical Preparations	Highland Management Partners VI L P	MA	DT		P.d	0	0.00	235	6	4,066	I
9/22/09 16:15	9/18/09	HLCS	Health	Drug	Pharmaceutical Preparations	Highland Capital Partners VI LP	MA	DT		P.d	0	0.00	152	2	7,418	D
9/22/09 16:15	9/18/09	HLCS	Health	Drug	Pharmaceutical Preparations	Hef Vi, Limited Partnership	MA	D		P.d	0	0.00	8	2	367	I
9/22/09 16:15	9/18/09	HLCS	Health	Drug	Pharmaceutical Preparations	Higgins Robert F	MA	DT		P.d	0	0.00	243	195	367	I
9/21/09 15:54	9/18/09	HLCS	Health	Drug	Pharmaceutical Preparations	Versant Venture Capital Ii, LP	CA	T		P.d	625	2.57	243	2	10,710	I
9/21/09 15:35	9/18/09	HLCS	Health	Drug	Pharmaceutical Preparations	Colella Samuel D	CA	T		P.d	625	2.57	243	2	10,710	I
9/21/09 14:35	9/18/09	HLCS	Health	Drug	Pharmaceutical Preparations	Atwood Brian G	CA	DT		P.d	625	2.57	243	2	10,710	I
12/29/08 16:18	12/23/08	HLCS	Health	Drug	Pharmaceutical Preparations	Colella Samuel D	CA	T		P.d	0	0.00	8,621	404	10,756	I
12/29/08 16:14	12/23/08	HLCS	Health	Drug	Pharmaceutical Preparations	Versant Venture Capital Ii, LP	CA	T		P.d	0	0.00	8,621	404	10,756	I
12/29/08 16:03	12/23/08	HLCS	Health	Drug	Pharmaceutical Preparations	Atwood Brian G	CA	DT		P.d	0	0.00	8,621	404	10,756	I
12/29/08 15:00	12/23/08	HLCS	Health	Drug	Pharmaceutical Preparations	Atlas Venture Fund V LP	MA	DT		P.d	0	0.00	8,621	289	11,608	I
12/29/08 14:54	12/23/08	HLCS	Health	Drug	Pharmaceutical Preparations	Hef Vi, Limited Partnership	MA	D		P.d	0	0.00	267	289	360	I
12/29/08 14:53	12/23/08	HLCS	Health	Drug	Pharmaceutical Preparations	Highland Capital Partners VI LP	MA	DT		P.d	0	0.00	5,395	289	7,266	D
12/29/08 14:53	12/23/08	HLCS	Health	Drug	Pharmaceutical Preparations	Highland Management Partners VI L P	MA	DT		P.d	0	0.00	8,353		3,983	I
12/29/08 14:52	12/23/08	HLCS	Health	Drug	Pharmaceutical Preparations	Higgins Robert F	MA	D		P.d	0	0.00	8,621		360	I
12/29/08 14:32	12/23/08	HLCS	Health	Drug	Pharmaceutical Preparations	Afeyan Noubar	MA	DT		P.d	0	0.00	8,621	259	11,950	I
12/29/08 14:32	12/23/08	HLCS	Health	Drug	Pharmaceutical Preparations	Agtc Advisors Fund LP	MA	DT		P.d	0	0.00	8,621	259	11,950	I
12/29/08 14:30	12/23/08	HLCS	Health	Drug	Pharmaceutical Preparations	Barrett Peter	MA	DT		P.d	0	0.00	8,621	289	11,608	I
5/28/08 10:26	5/27/08	HLCS	Health	Drug	Pharmaceutical Preparations	Allison Elisabeth	MA	D		P	5	4.98	1	New	1	D
6/1/07 16:23	5/30/07	HLCS	Health	Drug	Pharmaceutical Preparations	Colella Samuel D	CA	T		P.d	1,000	9.00	111	202	166	I
6/1/07 16:22	5/30/07	HLCS	Health	Drug	Pharmaceutical Preparations	Versant Venture Capital Ii, LP	CA	T		P.d	1,000	9.00	111	202	166	I
6/1/07 16:21	5/30/07	HLCS	Health	Drug	Pharmaceutical Preparations	Atwood Brian G	CA	DT		P.d	1,000	9.00	111	202	166	I
5/31/07 19:19	5/30/07	HLCS	Health	Drug	Pharmaceutical Preparations	Evnin Luke	MA	T		P.d	3,000	9.00	333	13	2,988	I
5/31/07 19:18	5/30/07	HLCS	Health	Drug	Pharmaceutical Preparations	Mpm Bioventures III Qp LP	MA	T		P.d	3,000	9.00	333	13	2,988	I
5/31/07 12:36	5/30/07	HLCS	Health	Drug	Pharmaceutical Preparations	Agtc Advisors Fund LP	MA	T		P.d	2,000	9.00	222	7	3,329	I
5/31/07 12:35	5/30/07	HLCS	Health	Drug	Pharmaceutical Preparations	Atlas Venture Fund V LP	MA	T		P.d	3,000	9.00	333	13	2,988	I
5/31/07 12:29	5/30/07	HLCS	Health	Drug	Pharmaceutical Preparations	Afeyan Noubar	MA	DT		P.d	2,000	9.00	222	7	3,329	I
5/31/07 12:24	5/30/07	HLCS	Health	Drug	Pharmaceutical Preparations	Barrett Peter	MA	DT		P.d	3,000	9.00	333	13	2,988	I
5/31/07 12:23	5/30/07	HLCS	Health	Drug	Pharmaceutical Preparations	Higgins Robert F	MA	D		P.d	3,000	9.00	333		10	I
5/31/07 12:23	5/30/07	HLCS	Health	Drug	Pharmaceutical Preparations	Highland Capital Partners VI LP	MA	T		P.d	1,878	9.00	209	New	209	D
5/31/07 12:22	5/30/07	HLCS	Health	Drug	Pharmaceutical Preparations	Highland Management Partners VI L P	MA	T		P.d	2,907	9.00	323		114	I

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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