Baker Bros. Advisors LP - Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	Title	T	TVal	Price	Qty	oc	Own	H
12/31/24 16:00	12/30/24	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Baker Bros. Advisors LP	NY	T		P	2,000	6.44	311	40	1,083	I
12/17/24 18:03	12/13/24	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Baker Bros. Advisors LP	NY	DT		P.m	21,230	14.29	1,485	17	9,995	I
12/10/24 21:25	12/9/24	BGNE	Beigene, Ltd.		Health	Drug	Pharmaceutical Preparations	Baker Bros. Advisors LP	NY	D		S	-194,200	187.27	-1,037	-10	9,013	I
8/22/24 16:03	8/20/24	KYMR	Kymera Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Baker Bros. Advisors LP	NY	D		P.d	0	46.41	0	0	5,996	I
5/9/24 18:25	5/7/24	INCY	Incyte Corp	DE	Health	Biolab	Commercial Physical & Biologi	Baker Bros. Advisors LP	NY	DT		M.d	1,470	49.01	30	0	34,056	I
3/28/24 19:04	3/26/24	IGMS	Igm Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Baker Bros. Advisors LP	NY	DT		P.m	3,426	8.67	395	12	3,753	I
12/15/23 17:32	12/13/23	IGMS	Igm Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Baker Bros. Advisors LP	NY	DT		P.m	3,431	6.44	533	19	3,390	I
12/14/23 18:10	12/13/23	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Baker Bros. Advisors LP	NY	D		P.m	22,517	221.20	102	6	1,793	I
12/14/23 18:09	12/12/23	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Baker Bros. Advisors LP	NY	D		P	7,549	218.31	35	2	1,699	I
11/21/23 18:15	11/21/23	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Baker Bros. Advisors LP	NY	D		P	12,128	188.48	64	4	1,667	I
11/21/23 18:14	11/17/23	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Baker Bros. Advisors LP	NY	D		P.m	11,947	178.11	67	4	1,608	I
11/15/23 17:13	11/14/23	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Baker Bros. Advisors LP	NY	D		P.m	7,810	158.13	49	3	1,546	I
11/15/23 17:12	11/13/23	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Baker Bros. Advisors LP	NY	D		P.m	15,801	146.99	107	8	1,500	I
10/23/23 16:49	10/19/23	BCEL	Atreca, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Baker Bros. Advisors LP	NY	H	Former 1	S	-111	0.4025	-275	-8	2,971	I
8/17/23 17:08	8/15/23	NLTX	Neoleukin Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Baker Bros. Advisors LP	NY	DT		P.m	1,463	0.6404	2,285	69	5,617	I
5/24/23 17:09	5/22/23	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Baker Bros. Advisors LP	NY	DT		P.dm	22,707	25.33	897	2	39,523	I
5/24/23 17:09	5/23/23	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Baker Bros. Advisors LP	NY	DT		M.d	425	17.01	25	0	39,523	I
5/3/23 16:04	5/1/23	SGEN	Seagen Inc.	WA	Health	BioPrd	Biological Products, (No Diag	Baker Bros. Advisors LP	NY	DT		M.d	642	36.70	18	1	1,752	M
3/15/23 16:03	3/13/23	INCY	Incyte Corp	DE	Health	Biolab	Commercial Physical & Biologi	Baker Bros. Advisors LP	NY	DT		M.d	910	22.74	40	0	34,036	I
1/17/23 16:22	1/12/23	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Baker Bros. Advisors LP	NY	DT		M.d	157	5.22	30	0	38,691	I
6/6/22 17:08	6/2/22	KOD	Kodiak Sciences Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Baker Bros. Advisors LP	NY	DT		P.m	4,448	7.77	572	4	15,968	I
6/6/22 17:07	6/2/22	TRDA	Entrada Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Baker Bros. Advisors LP	NY	T		P.m	261	6.37	41	1	4,502	I
5/24/22 18:39	5/20/22	TRDA	Entrada Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Baker Bros. Advisors LP	NY	T		P.m	282	5.82	49	1	4,465	I
5/18/22 17:38	5/16/22	TRDA	Entrada Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Baker Bros. Advisors LP	NY	T		P.m	431	5.99	72	2	4,422	I
5/18/22 17:30	5/16/22	KOD	Kodiak Sciences Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Baker Bros. Advisors LP	NY	DT		P.m	2,697	5.91	457	3	15,142	I

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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