Opaleye Management Inc. - Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	T	TVal	Price	Qty	oc	Own	H
7/1/25 16:05	6/27/25	CDXS	Codexis, Inc.	DE	Chem	OChm	Industrial Organic Chemicals	Opaleye Management Inc.	MA	T	P	239	2.39	100	1	12,600	I
6/16/25 16:59	6/12/25	CDXS	Codexis, Inc.	DE	Chem	OChm	Industrial Organic Chemicals	Opaleye Management Inc.	MA	T	P.m	560	2.24	250	2	12,500	I
6/12/25 16:32	6/10/25	ETON	Eton Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T	P	125	15.82	8	0	2,855	I
5/28/25 16:05	5/23/25	CDXS	Codexis, Inc.	DE	Chem	OChm	Industrial Organic Chemicals	Opaleye Management Inc.	MA	T	P.m	5,487	2.36	2,325	23	12,250	I
5/2/25 16:05	4/30/25	CDXS	Codexis, Inc.	DE	Chem	OChm	Industrial Organic Chemicals	Opaleye Management Inc.	MA	T	P.m	104	2.31	45	0	9,925	I
4/30/25 19:06	4/29/25	SNWV	Sanuwave Health, Inc.	NV	Health	MdEq	Surgical & Medical Instrument	Opaleye Management Inc.	MA	T	P	204	25.49	8	1	980	I
4/29/25 16:05	4/25/25	CDXS	Codexis, Inc.	DE	Chem	OChm	Industrial Organic Chemicals	Opaleye Management Inc.	MA	T	P	56	2.24	25	0	9,880	I
4/17/25 18:07	4/15/25	CDXS	Codexis, Inc.	DE	Chem	OChm	Industrial Organic Chemicals	Opaleye Management Inc.	MA	T	P.m	299	2.13	140	1	9,855	I
4/9/25 16:05	4/8/25	CDXS	Codexis, Inc.	DE	Chem	OChm	Industrial Organic Chemicals	Opaleye Management Inc.	MA	T	P	198	1.98	100	1	9,715	I
4/3/25 19:39	4/1/25	CDXS	Codexis, Inc.	DE	Chem	OChm	Industrial Organic Chemicals	Opaleye Management Inc.	MA	T	P.m	272	2.36	115	1	9,615	I
3/24/25 16:05	3/20/25	CDXS	Codexis, Inc.	DE	Chem	OChm	Industrial Organic Chemicals	Opaleye Management Inc.	MA	T	P.m	236	2.54	93	1	9,500	I
3/14/25 16:05	3/13/25	CDXS	Codexis, Inc.	DE	Chem	OChm	Industrial Organic Chemicals	Opaleye Management Inc.	MA	T	P	216	2.54	85	1	9,150	I
3/10/25 17:16	3/6/25	CDXS	Codexis, Inc.	DE	Chem	OChm	Industrial Organic Chemicals	Opaleye Management Inc.	MA	T	P	261	2.61	100	1	9,065	I
3/6/25 16:51	3/4/25	CDXS	Codexis, Inc.	DE	Chem	OChm	Industrial Organic Chemicals	Opaleye Management Inc.	MA	T	P.m	172	2.65	65	1	8,965	I
3/4/25 16:05	2/28/25	CDXS	Codexis, Inc.	DE	Chem	OChm	Industrial Organic Chemicals	Opaleye Management Inc.	MA	T	P.m	574	2.95	195	2	8,900	I
2/12/25 19:42	2/10/25	CDXS	Codexis, Inc.	DE	Chem	OChm	Industrial Organic Chemicals	Opaleye Management Inc.	MA	T	P.m	205	4.11	50	1	8,705	I
1/31/25 19:08	1/30/25	CDXS	Codexis, Inc.	DE	Chem	OChm	Industrial Organic Chemicals	Opaleye Management Inc.	MA	T	P.m	283	4.35	65	1	8,655	I
1/2/25 16:05	12/30/24	CDXS	Codexis, Inc.	DE	Chem	OChm	Industrial Organic Chemicals	Opaleye Management Inc.	MA	T	P.m	211	4.69	45	1	8,590	I
11/1/24 19:47	10/30/24	SNWVD	Sanuwave Health, Inc.	NV	Health	MdEq	Surgical & Medical Instrument	Opaleye Management Inc.	MA	T	P.m	439	15.75	28	3	972	I
10/28/24 16:05	10/25/24	CDXS	Codexis, Inc.	DE	Chem	OChm	Industrial Organic Chemicals	Opaleye Management Inc.	MA	T	P	73	2.91	25	0	8,545	I
10/25/24 16:05	10/23/24	ETON	Eton Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T	P	80	7.98	10	0	2,770	I
10/8/24 18:34	10/4/24	ETON	Eton Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T	P.m	434	6.99	62	2	2,812	I
9/26/24 15:21	9/24/24	CDXS	Codexis, Inc.	DE	Chem	OChm	Industrial Organic Chemicals	Opaleye Management Inc.	MA	T	P.m	249	2.93	85	1	8,520	I
9/23/24 17:19	9/20/24	CDXS	Codexis, Inc.	DE	Chem	OChm	Industrial Organic Chemicals	Opaleye Management Inc.	MA	T	P.m	3,308	3.01	1,100	15	8,685	I
9/19/24 18:16	9/18/24	CDXS	Codexis, Inc.	DE	Chem	OChm	Industrial Organic Chemicals	Opaleye Management Inc.	MA	T	P	193	3.16	61	1	7,585	I
9/12/24 19:31	9/10/24	ETON	Eton Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T	P.m	505	4.70	108	4	2,780	I
4/25/24 17:19	4/25/24	HROW	Harrow, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T	P	199	9.97	20	1	3,815	I
4/24/24 16:40	4/23/24	HROW	Harrow, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T	P.m	205	10.23	20	1	3,795	I
4/19/24 18:24	4/19/24	HROW	Harrow, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T	P	310	10.56	29	1	3,775	I
3/28/24 18:07	3/28/24	HROW	Harrow, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T	P	641	12.82	50	1	3,746	I
3/22/24 11:52	3/20/24	HROW	Harrow, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T	P	488	9.65	51	1	3,696	I
11/16/23 16:05	11/15/23	HROW	Harrow, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T	P	201	8.03	25	1	3,645	I
9/20/23 18:39	9/19/23	HROW	Harrow Health, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T	P.m	292	14.60	20	1	3,620	I
3/13/23 16:05	3/9/23	TCON	Tracon Pharmaceuticals, Inc.		Health	BioPrd	Biological Products, (No Diag	Opaleye Management Inc.	MA	T	P.d	241	1.38	175	4	4,325	I
12/16/22 17:03	12/14/22	TCON	Tracon Pharmaceuticals, Inc.		Health	BioPrd	Biological Products, (No Diag	Opaleye Management Inc.	MA	T	P.d	210	1.25	168	4	4,590	I
12/14/22 16:05	12/14/22	HROW	Harrow Health, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T	P	4,536	10.52	431	13	3,775	I
11/4/22 16:03	11/3/22	TELA	Tela Bio, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Opaleye Management Inc.	MA	T	P	158	7.81	20	1	2,073	I
10/19/22 19:22	10/18/22	TCON	Tracon Pharmaceuticals, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Opaleye Management Inc.	MA	T	P.d	21	1.65	13	0	7,915	I
10/11/22 19:29	10/11/22	TELA	Tela Bio, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Opaleye Management Inc.	MA	T	P	128	8.00	16	1	2,053	I
10/3/22 16:06	9/29/22	TCON	Tracon Pharmaceuticals, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Opaleye Management Inc.	MA	T	P.d	16	1.74	9	2	410	I

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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