Opaleye Management Inc. - Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	T	TVal	Price	Qty	oc	Own	H
4/9/25 16:05	4/8/25	CDXS	Codexis, Inc.	DE	Chem	OChm	Industrial Organic Chemicals	Opaleye Management Inc.	MA	T	P	198	1.98	100	1	9,715	I
4/3/25 19:39	4/1/25	CDXS	Codexis, Inc.	DE	Chem	OChm	Industrial Organic Chemicals	Opaleye Management Inc.	MA	T	P.m	272	2.36	115	1	9,615	I
3/26/25 16:05	3/18/25	HROW	Harrow, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T	S	-150	30.01	-5	0	3,950	I
3/24/25 16:05	3/20/25	CDXS	Codexis, Inc.	DE	Chem	OChm	Industrial Organic Chemicals	Opaleye Management Inc.	MA	T	P.m	236	2.54	93	1	9,500	I
3/20/25 16:05	3/18/25	HROW	Harrow, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T	S	-148	29.64	-5	0	3,955	I
3/14/25 16:05	3/13/25	CDXS	Codexis, Inc.	DE	Chem	OChm	Industrial Organic Chemicals	Opaleye Management Inc.	MA	T	P	216	2.54	85	1	9,150	I
3/10/25 17:16	3/6/25	CDXS	Codexis, Inc.	DE	Chem	OChm	Industrial Organic Chemicals	Opaleye Management Inc.	MA	T	P	261	2.61	100	1	9,065	I
3/6/25 16:51	3/4/25	CDXS	Codexis, Inc.	DE	Chem	OChm	Industrial Organic Chemicals	Opaleye Management Inc.	MA	T	P.m	172	2.65	65	1	8,965	I
3/4/25 16:44	2/28/25	HROW	Harrow, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T	S	-140	28.05	-5	-3	150	I
3/4/25 16:05	2/28/25	CDXS	Codexis, Inc.	DE	Chem	OChm	Industrial Organic Chemicals	Opaleye Management Inc.	MA	T	P.m	574	2.95	195	2	8,900	I
2/12/25 19:42	2/10/25	CDXS	Codexis, Inc.	DE	Chem	OChm	Industrial Organic Chemicals	Opaleye Management Inc.	MA	T	P.m	205	4.11	50	1	8,705	I
1/31/25 19:08	1/30/25	CDXS	Codexis, Inc.	DE	Chem	OChm	Industrial Organic Chemicals	Opaleye Management Inc.	MA	T	P.m	283	4.35	65	1	8,655	I
1/24/25 21:29	1/22/25	HROW	Harrow, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T	S	-712	35.59	-20	-11	155	I
1/2/25 16:05	12/30/24	CDXS	Codexis, Inc.	DE	Chem	OChm	Industrial Organic Chemicals	Opaleye Management Inc.	MA	T	P.m	211	4.69	45	1	8,590	I
11/1/24 19:47	10/30/24	SNWVD	Sanuwave Health, Inc.	NV	Health	MdEq	Surgical & Medical Instrument	Opaleye Management Inc.	MA	T	P.m	439	15.75	28	3	972	I
10/28/24 16:05	10/25/24	CDXS	Codexis, Inc.	DE	Chem	OChm	Industrial Organic Chemicals	Opaleye Management Inc.	MA	T	P	73	2.91	25	0	8,545	I
10/25/24 16:05	10/23/24	ETON	Eton Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T	P	80	7.98	10	0	2,770	I
10/8/24 18:34	10/4/24	ETON	Eton Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T	P.m	434	6.99	62	2	2,812	I
9/26/24 15:21	9/24/24	CDXS	Codexis, Inc.	DE	Chem	OChm	Industrial Organic Chemicals	Opaleye Management Inc.	MA	T	P.m	249	2.93	85	1	8,520	I
9/23/24 17:19	9/20/24	CDXS	Codexis, Inc.	DE	Chem	OChm	Industrial Organic Chemicals	Opaleye Management Inc.	MA	T	P.m	3,308	3.01	1,100	15	8,685	I
9/19/24 18:16	9/18/24	CDXS	Codexis, Inc.	DE	Chem	OChm	Industrial Organic Chemicals	Opaleye Management Inc.	MA	T	P	193	3.16	61	1	7,585	I
9/12/24 20:20	9/11/24	TARA	Protara Therapeutics, Inc.		Health	BioPrd	Biological Products, (No Diag	Opaleye Management Inc.	MA	T	S.m	-272	1.71	-159	-7	1,989	I
9/12/24 19:31	9/10/24	ETON	Eton Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T	P.m	505	4.70	108	4	2,780	I
9/10/24 19:11	9/9/24	TARA	Protara Therapeutics, Inc.		Health	BioPrd	Biological Products, (No Diag	Opaleye Management Inc.	MA	T	S.m	-114	1.84	-62	-3	2,148	I
7/18/24 16:05	7/16/24	TARA	Protara Therapeutics, Inc.		Health	BioPrd	Biological Products, (No Diag	Opaleye Management Inc.	MA	T	S	-28	2.44	-11	-1	2,210	I
7/11/24 19:56	7/9/24	TARA	Protara Therapeutics, Inc.		Health	BioPrd	Biological Products, (No Diag	Opaleye Management Inc.	MA	T	S.m	-176	2.36	-75	-3	2,221	I
7/3/24 14:00	7/1/24	TARA	Protara Therapeutics, Inc.		Health	BioPrd	Biological Products, (No Diag	Opaleye Management Inc.	MA	T	S	-18	2.12	-8	0	2,301	I
6/28/24 18:45	6/27/24	TARA	Protara Therapeutics, Inc.		Health	BioPrd	Biological Products, (No Diag	Opaleye Management Inc.	MA	T	S.m	-143	2.21	-65	-3	2,304	I
6/27/24 16:05	6/25/24	TARA	Protara Therapeutics, Inc.		Health	BioPrd	Biological Products, (No Diag	Opaleye Management Inc.	MA	T	S	-29	2.26	-13	-1	2,369	I
5/31/24 16:05	5/30/24	TARA	Protara Therapeutics, Inc.		Health	BioPrd	Biological Products, (No Diag	Opaleye Management Inc.	MA	T	S.m	-44	2.92	-15	-12	109	I
5/23/24 19:01	5/21/24	TARA	Protara Therapeutics, Inc.		Health	BioPrd	Biological Products, (No Diag	Opaleye Management Inc.	MA	T	S.m	-130	3.05	-43	-2	2,406	I
5/17/24 19:48	5/17/24	TARA	Protara Therapeutics, Inc.		Health	BioPrd	Biological Products, (No Diag	Opaleye Management Inc.	MA	T	S	-230	3.25	-71	-3	2,439	I
5/10/24 18:57	5/9/24	TARA	Protara Therapeutics, Inc.		Health	BioPrd	Biological Products, (No Diag	Opaleye Management Inc.	MA	T	S.m	-567	3.11	-182	-7	2,380	I
4/25/24 17:19	4/25/24	HROW	Harrow, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T	P	199	9.97	20	1	3,815	I
4/24/24 16:40	4/23/24	HROW	Harrow, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T	P.m	205	10.23	20	1	3,795	I
4/19/24 18:24	4/19/24	HROW	Harrow, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T	P	310	10.56	29	1	3,775	I
3/28/24 18:07	3/28/24	HROW	Harrow, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T	P	641	12.82	50	1	3,746	I
3/22/24 11:52	3/20/24	HROW	Harrow, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T	P	488	9.65	51	1	3,696	I
11/16/23 16:05	11/15/23	HROW	Harrow, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T	P	201	8.03	25	1	3,645	I
9/20/23 18:39	9/19/23	HROW	Harrow Health, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T	P.m	292	14.60	20	1	3,620	I
3/13/23 16:05	3/9/23	TCON	Tracon Pharmaceuticals, Inc.		Health	BioPrd	Biological Products, (No Diag	Opaleye Management Inc.	MA	T	P.d	241	1.38	175	4	4,325	I
12/30/22 18:00	12/30/22	TARA	Protara Therapeutics, Inc.		Health	BioPrd	Biological Products, (No Diag	Opaleye Management Inc.	MA	T	S	-42	2.71	-15	-1	2,693	I
12/16/22 17:03	12/14/22	TCON	Tracon Pharmaceuticals, Inc.		Health	BioPrd	Biological Products, (No Diag	Opaleye Management Inc.	MA	T	P.d	210	1.25	168	4	4,590	I
12/14/22 16:05	12/14/22	HROW	Harrow Health, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T	P	4,536	10.52	431	13	3,775	I
12/8/22 18:49	12/6/22	TCON	Tracon Pharmaceuticals, Inc.		Health	BioPrd	Biological Products, (No Diag	Opaleye Management Inc.	MA	T	S.d	-2	1.44	-2	0	8,135	I
11/4/22 16:03	11/3/22	TELA	Tela Bio, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Opaleye Management Inc.	MA	T	P	158	7.81	20	1	2,073	I
10/19/22 19:22	10/18/22	TCON	Tracon Pharmaceuticals, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Opaleye Management Inc.	MA	T	P.d	21	1.65	13	0	7,915	I
10/11/22 19:29	10/11/22	TELA	Tela Bio, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Opaleye Management Inc.	MA	T	P	128	8.00	16	1	2,053	I
10/3/22 16:06	9/29/22	TCON	Tracon Pharmaceuticals, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Opaleye Management Inc.	MA	T	P.d	16	1.74	9	2	410	I
9/30/22 06:15	9/28/22	HROW	Harrow Health, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T	P	108	9.77	11	0	3,344	I
9/28/22 18:00	9/27/22	TCON	Tracon Pharmaceuticals, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Opaleye Management Inc.	MA	T	P.d	3	1.69	2	0	401	I
9/26/22 16:05	9/23/22	TELA	Tela Bio, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Opaleye Management Inc.	MA	T	P	54	7.99	7	0	2,037	I
9/22/22 18:09	9/22/22	TCON	Tracon Pharmaceuticals, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Opaleye Management Inc.	MA	T	P.d	30	1.73	17	0	4,179	I
9/20/22 17:37	9/20/22	TCON	Tracon Pharmaceuticals, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Opaleye Management Inc.	MA	T	P.d	19	1.85	10	3	385	I
9/19/22 19:27	9/19/22	TELA	Tela Bio, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Opaleye Management Inc.	MA	T	P	146	8.09	18	1	2,030	I
9/19/22 19:00	9/19/22	TCON	Tracon Pharmaceuticals, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Opaleye Management Inc.	MA	T	P.d	9	1.87	5	1	375	I
9/16/22 17:47	9/15/22	TELA	Tela Bio, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Opaleye Management Inc.	MA	T	P.m	53	8.09	7	0	2,012	I
9/15/22 16:05	8/16/22	TELA	Tela Bio, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Opaleye Management Inc.	MA	T	P	42	8.10	5	0	2,005	I
9/15/22 16:05	9/14/22	TARA	Protara Therapeutics, Inc.		Health	BioPrd	Biological Products, (No Diag	Opaleye Management Inc.	MA	T	P.m	94	3.93	24	1	2,708	I
8/16/22 16:05	8/16/22	TELA	Tela Bio, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Opaleye Management Inc.	MA	T	P	2,520	8.00	315	19	2,000	I
8/12/22 09:27	8/1/22	TELA	Tela Bio, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Opaleye Management Inc.	MA	T	P.a	40	7.96	5	0	1,669	I
8/12/22 06:41	8/10/22	TELA	Tela Bio, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Opaleye Management Inc.	MA	T	P	102	8.52	12	1	1,685	I
8/2/22 21:39	8/1/22	TELA	Tela Bio, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Opaleye Management Inc.	MA	T	P	40	7.96	5	0	1,666	I
7/26/22 17:25	7/26/22	TCON	Tracon Pharmaceuticals, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Opaleye Management Inc.	MA	T	P.d	4	1.72	2	1	370	I
7/22/22 17:48	7/22/22	TELA	Tela Bio, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Opaleye Management Inc.	MA	T	P	42	8.02	5	0	1,664	I
7/21/22 17:50	7/21/22	TELA	Tela Bio, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Opaleye Management Inc.	MA	T	P	83	8.03	10	1	1,659	I
7/20/22 18:55	7/20/22	TELA	Tela Bio, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Opaleye Management Inc.	MA	T	P	41	8.08	5	0	1,649	I
7/15/22 18:06	7/15/22	TCON	Tracon Pharmaceuticals, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Opaleye Management Inc.	MA	T	P.d	21	1.78	12	3	368	I
7/14/22 18:25	7/14/22	TCON	Tracon Pharmaceuticals, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Opaleye Management Inc.	MA	T	P.d	13	1.81	7	2	356	I

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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