RYTM - Rhythm Pharmaceuticals, Inc. - Insider Stock Trading

Filing Date	T Date	Ticker	Sector	Ind	Industry	Owner	oSt	Rel	Title	T	TVal	Price	Qty	oc	Own	H
4/16/24 20:11	4/14/24	RYTM	Health	Drug	Pharmaceutical Preparations	Mazabraud Yann	MA	O	EVP,Head	M.d	0	0.00	10	42	35	D
4/3/24 20:00	3/20/24	RYTM	Health	Drug	Pharmaceutical Preparations	German Christopher Paul	MA	O	Corporat	M.d	0	0.00	1		1	D
4/3/24 20:00	4/2/24	RYTM	Health	Drug	Pharmaceutical Preparations	German Christopher Paul	MA	O	Corporat	S.d	-15	41.76	0	-32	1	D
3/22/24 16:55	3/21/24	RYTM	Health	Drug	Pharmaceutical Preparations	Shulman Joseph	MA	O	Chief Te	S	-736	40.34	-18	-100	0	D
3/22/24 16:16	3/20/24	RYTM	Health	Drug	Pharmaceutical Preparations	Lee Jennifer Kayden	MA	O	EVP,Head	S	-707	38.77	-18	-73	7	D
3/19/24 20:57	3/19/24	RYTM	Health	Drug	Pharmaceutical Preparations	Smith Hunter C	MA	O	CFO	S	-608	39.22	-16	-14	98	D
3/19/24 20:56	3/19/24	RYTM	Health	Drug	Pharmaceutical Preparations	Shulman Joseph	MA	O	Chief Te	S	-608	39.22	-16	-46	18	D
3/19/24 20:54	3/19/24	RYTM	Health	Drug	Pharmaceutical Preparations	Meeker David P	MA	DO	P,CEO	S	-1,784	39.22	-45	-21	175	D
3/19/24 20:53	3/19/24	RYTM	Health	Drug	Pharmaceutical Preparations	Mazabraud Yann	MA	O	EVP,Head	S	-628	39.22	-16	-40	24	D
3/19/24 20:52	3/19/24	RYTM	Health	Drug	Pharmaceutical Preparations	Lee Jennifer Kayden	MA	O	EVP,Head	S	-608	39.22	-16	-38	25	D
3/19/24 20:50	3/19/24	RYTM	Health	Drug	Pharmaceutical Preparations	Cramer Pamela J.	MA	O	CHRO	S	-608	39.22	-16	-34	30	D
2/15/24 18:14	2/13/24	RYTM	Health	Drug	Pharmaceutical Preparations	Shulman Joseph	MA	O	Chief Te	S.m	-148	50.00	-3	-99	0	D
2/13/24 20:50	2/9/24	RYTM	Health	Drug	Pharmaceutical Preparations	Smith Hunter C	MA	O	CFO	M.dm	0	0.00	6	9	80	D
2/13/24 20:50	2/12/24	RYTM	Health	Drug	Pharmaceutical Preparations	Smith Hunter C	MA	O	CFO	S.dm	-97	50.80	-2	-2	80	D
2/13/24 20:49	2/9/24	RYTM	Health	Drug	Pharmaceutical Preparations	Mazabraud Yann	MA	O	EVP,Head	M.dm	0	0.00	5	429	7	D
2/13/24 20:49	2/12/24	RYTM	Health	Drug	Pharmaceutical Preparations	Mazabraud Yann	MA	O	EVP,Head	S.dm	-130	50.80	-3	-27	7	D
2/13/24 20:47	2/9/24	RYTM	Health	Drug	Pharmaceutical Preparations	Lee Jennifer Kayden	MA	O	EVP,Head	M.dm	0	0.00	5	395	7	D
2/13/24 20:47	2/12/24	RYTM	Health	Drug	Pharmaceutical Preparations	Lee Jennifer Kayden	MA	O	EVP,Head	S.dm	-83	50.80	-2	-19	7	D
2/13/24 20:46	2/9/24	RYTM	Health	Drug	Pharmaceutical Preparations	Shulman Joseph	MA	O	Chief Te	M.dm	1,479	20.15	73		3	D
2/13/24 20:46	2/9/24	RYTM	Health	Drug	Pharmaceutical Preparations	Shulman Joseph	MA	O	Chief Te	S.dm	-3,680	50.39	-73	-96	3	D
2/13/24 20:45	2/9/24	RYTM	Health	Drug	Pharmaceutical Preparations	Cramer Pamela J.	MA	O	CHRO	M.d	0	0.00	2	25	12	D
2/13/24 20:45	2/12/24	RYTM	Health	Drug	Pharmaceutical Preparations	Cramer Pamela J.	MA	O	CHRO	S.d	-36	51.38	-1	-6	12	D
2/5/24 18:55	2/1/24	RYTM	Health	Drug	Pharmaceutical Preparations	Lee Jennifer Kayden	MA	O	EVP,Head	M.d	0	0.00	5		3	D
2/5/24 18:55	2/1/24	RYTM	Health	Drug	Pharmaceutical Preparations	Lee Jennifer Kayden	MA	O	EVP,Head	S.d	-67	45.06	-1	-33	3	D
2/5/24 18:54	2/1/24	RYTM	Health	Drug	Pharmaceutical Preparations	Smith Hunter C	MA	O	CFO	M.d	0	0.00	5	7	75	D
2/5/24 18:54	2/1/24	RYTM	Health	Drug	Pharmaceutical Preparations	Smith Hunter C	MA	O	CFO	S.d	-73	45.06	-2	-2	75	D
2/5/24 18:54	2/1/24	RYTM	Health	Drug	Pharmaceutical Preparations	Shulman Joseph	MA	O	Chief Te	M.d	0	0.00	4		3	D
2/5/24 18:54	2/1/24	RYTM	Health	Drug	Pharmaceutical Preparations	Shulman Joseph	MA	O	Chief Te	S.d	-60	45.06	-1	-34	3	D
2/5/24 18:53	2/1/24	RYTM	Health	Drug	Pharmaceutical Preparations	Meeker David P	MA	DO	P,CEO	M.d	0	0.00	14	13	121	D
2/5/24 18:53	2/1/24	RYTM	Health	Drug	Pharmaceutical Preparations	Meeker David P	MA	DO	P,CEO	S.d	-197	45.06	-4	-3	121	D
2/5/24 18:53	2/1/24	RYTM	Health	Drug	Pharmaceutical Preparations	Cramer Pamela J.	MA	O	CHRO	M.d	0	0.00	3	35	10	D
2/5/24 18:53	2/1/24	RYTM	Health	Drug	Pharmaceutical Preparations	Cramer Pamela J.	MA	O	CHRO	S.d	-43	45.06	-1	-9	10	D
1/3/24 16:15	12/29/23	RYTM	Health	Drug	Pharmaceutical Preparations	Smith Hunter C	MA	O	CFO	M.d	72	6.88	11	17	72	D
12/29/23 16:30	12/27/23	RYTM	Health	Drug	Pharmaceutical Preparations	Shulman Joseph	MA	O	Chief Te	M.dm	197	21.38	9		0	D
12/29/23 16:30	12/27/23	RYTM	Health	Drug	Pharmaceutical Preparations	Shulman Joseph	MA	O	Chief Te	S.dm	-647	50.01	-13	-100	0	D
12/7/23 16:16	12/5/23	RYTM	Health	Drug	Pharmaceutical Preparations	Smith Hunter C	MA	O	CFO	M.dm	186	6.88	27	79	61	D
12/7/23 16:16	12/5/23	RYTM	Health	Drug	Pharmaceutical Preparations	Smith Hunter C	MA	O	CFO	S.dm	-1,046	38.72	-27	-31	61	D
11/28/23 16:05	11/24/23	RYTM	Health	Drug	Pharmaceutical Preparations	Smith Hunter C	MA	O	CFO	M.d	76	6.88	11	22	61	D
11/28/23 16:05	11/24/23	RYTM	Health	Drug	Pharmaceutical Preparations	Smith Hunter C	MA	O	CFO	S.d	-384	35.02	-11	-15	61	D
11/16/23 16:05	11/14/23	RYTM	Health	Drug	Pharmaceutical Preparations	Shulman Joseph	MA	O	Chief Te	M.d	190	6.80	28		4	D
11/16/23 16:05	11/14/23	RYTM	Health	Drug	Pharmaceutical Preparations	Shulman Joseph	MA	O	Chief Te	S.d	-894	32.07	-28	-88	4	D
11/16/23 16:05	11/14/23	RYTM	Health	Drug	Pharmaceutical Preparations	Lee Jennifer Kayden	MA	O	EVP,Head	M.d	82	6.80	12		0	D
11/16/23 16:05	11/14/23	RYTM	Health	Drug	Pharmaceutical Preparations	Lee Jennifer Kayden	MA	O	EVP,Head	S.d	-438	32.01	-14	-100	0	D
11/16/23 16:05	11/14/23	RYTM	Health	Drug	Pharmaceutical Preparations	Smith Hunter C	MA	O	CFO	M.d	83	6.88	12	24	61	D
11/16/23 16:05	11/14/23	RYTM	Health	Drug	Pharmaceutical Preparations	Smith Hunter C	MA	O	CFO	S.d	-365	30.38	-12	-16	61	D
11/13/23 17:44	11/8/23	RYTM	Health	Drug	Pharmaceutical Preparations	Lee Jennifer Kayden	MA	O	EVP,Head	M.dm	62	6.80	9		2	D
11/13/23 17:44	11/8/23	RYTM	Health	Drug	Pharmaceutical Preparations	Lee Jennifer Kayden	MA	O	EVP,Head	S.dm	-260	28.45	-9	-85	2	D
11/7/23 18:17	11/3/23	RYTM	Health	Drug	Pharmaceutical Preparations	Lee Jennifer Kayden	MA	O	EVP,Head	M.d	1	6.80	0	5	2	D
11/7/23 18:17	11/3/23	RYTM	Health	Drug	Pharmaceutical Preparations	Lee Jennifer Kayden	MA	O	EVP,Head	S.d	-2	28.00	0	-5	2	D
9/7/23 17:48	9/5/23	RYTM	Health	Drug	Pharmaceutical Preparations	Lee Jennifer Kayden	MA	O	EVP,Head	M.d	31	6.80	5		2	D
9/7/23 17:48	9/5/23	RYTM	Health	Drug	Pharmaceutical Preparations	Lee Jennifer Kayden	MA	O	EVP,Head	S.d	-173	28.05	-6	-79	2	D
8/9/23 16:30	8/7/23	RYTM	Health	Drug	Pharmaceutical Preparations	Lee Jennifer Kayden	MA	O	EVP,Head	M.dm	70	6.80	10		3	D
8/9/23 16:30	8/7/23	RYTM	Health	Drug	Pharmaceutical Preparations	Lee Jennifer Kayden	MA	O	EVP,Head	S.dm	-314	24.24	-13	-80	3	D
7/28/23 21:01	7/26/23	RYTM	Health	Drug	Pharmaceutical Preparations	Cramer Pamela J.	MA	O	CHRO	M.d	0	0.00	3	59	8	D
7/28/23 21:01	7/26/23	RYTM	Health	Drug	Pharmaceutical Preparations	Cramer Pamela J.	MA	O	CHRO	S.d	-16	17.64	-1	-10	8	D
6/21/23 16:05	6/16/23	RYTM	Health	Drug	Pharmaceutical Preparations	Smith Hunter C	MA	O	CFO	M.d	14	6.88	2	3	61	D
3/31/23 21:38	3/29/23	RYTM	Health	Drug	Pharmaceutical Preparations	Roberts William T.	MA	O	Chief Ac	M.d	0	0.00	3	47	8	D
3/31/23 21:38	3/29/23	RYTM	Health	Drug	Pharmaceutical Preparations	Roberts William T.	MA	O	Chief Ac	S.d	-16	17.50	-1	-10	8	D
2/16/23 16:05	2/14/23	RYTM	Health	Drug	Pharmaceutical Preparations	Mazabraud Yann	MA	O	EVP,Head	S	-32	27.03	-1	-24	4	D
2/14/23 21:00	2/11/23	RYTM	Health	Drug	Pharmaceutical Preparations	Shulman Joseph	MA	O	Chief Te	M.d	0	0.00	2	72	4	D
2/14/23 21:00	2/14/23	RYTM	Health	Drug	Pharmaceutical Preparations	Shulman Joseph	MA	O	Chief Te	S.d	-15	26.87	-1	-13	4	D
2/14/23 20:59	2/11/23	RYTM	Health	Drug	Pharmaceutical Preparations	Chien Jennifer	MA	O	EVP,Head	M.d	0	0.00	2	70	5	D
2/14/23 20:59	2/14/23	RYTM	Health	Drug	Pharmaceutical Preparations	Chien Jennifer	MA	O	EVP,Head	S.d	-17	26.87	-1	-11	5	D
2/14/23 20:59	2/11/23	RYTM	Health	Drug	Pharmaceutical Preparations	Smith Hunter C	MA	O	CFO	M.d	0	0.00	2	4	59	D
2/14/23 20:59	2/14/23	RYTM	Health	Drug	Pharmaceutical Preparations	Smith Hunter C	MA	O	CFO	S.d	-19	26.87	-1	-1	59	D
2/14/23 20:57	2/11/23	RYTM	Health	Drug	Pharmaceutical Preparations	Mazabraud Yann	MA	O	EVP,Head	M.d	0	0.00	2	68	5	D
2/14/23 19:30	2/9/23	RYTM	Health	Drug	Pharmaceutical Preparations	Cramer Pamela J.	MA	O	CHRO	S.a	-23	27.51	-1	-12	6	D
2/14/23 19:27	2/9/23	RYTM	Health	Drug	Pharmaceutical Preparations	Mazabraud Yann	MA	O	EVP,Head	S.a	-43	27.51	-2	-34	3	D
2/14/23 19:27	2/9/23	RYTM	Health	Drug	Pharmaceutical Preparations	Roberts William T.	MA	O	Chief Ac	S.a	-27	27.51	-1	-13	6	D
2/14/23 19:26	2/9/23	RYTM	Health	Drug	Pharmaceutical Preparations	Shulman Joseph	MA	O	Chief Te	S.a	-26	27.51	-1	-25	3	D
2/14/23 19:19	2/9/23	RYTM	Health	Drug	Pharmaceutical Preparations	Chien Jennifer	MA	O	EVP,Head	S.a	-33	27.51	-1	-25	4	D
2/14/23 19:08	2/9/23	RYTM	Health	Drug	Pharmaceutical Preparations	Smith Hunter C	MA	O	CFO	S.a	-39	27.51	-1	-2	58	D
2/13/23 17:04	2/9/23	RYTM	Health	Drug	Pharmaceutical Preparations	Chien Jennifer	MA	O	EVP,Head	M.d	0	0.00	3	999%	4	D
2/13/23 17:04	2/9/23	RYTM	Health	Drug	Pharmaceutical Preparations	Chien Jennifer	MA	O	EVP,Head	S.d	-33	27.66	-1	-25	4	D
2/13/23 17:03	2/9/23	RYTM	Health	Drug	Pharmaceutical Preparations	Smith Hunter C	MA	O	CFO	M.d	0	0.00	4	8	58	D
2/13/23 17:03	2/9/23	RYTM	Health	Drug	Pharmaceutical Preparations	Smith Hunter C	MA	O	CFO	S.d	-39	27.66	-1	-2	58	D
2/13/23 17:03	2/9/23	RYTM	Health	Drug	Pharmaceutical Preparations	Mazabraud Yann	MA	O	EVP,Head	M.d	0	0.00	3		3	D
2/13/23 17:03	2/9/23	RYTM	Health	Drug	Pharmaceutical Preparations	Mazabraud Yann	MA	O	EVP,Head	S.d	-43	27.66	-2	-34	3	D
2/13/23 17:02	2/9/23	RYTM	Health	Drug	Pharmaceutical Preparations	Roberts William T.	MA	O	Chief Ac	M.d	0	0.00	2	58	6	D
2/13/23 17:02	2/9/23	RYTM	Health	Drug	Pharmaceutical Preparations	Roberts William T.	MA	O	Chief Ac	S.d	-27	27.66	-1	-13	6	D
2/13/23 17:02	2/9/23	RYTM	Health	Drug	Pharmaceutical Preparations	Cramer Pamela J.	MA	O	CHRO	M.d	0	0.00	2	62	6	D
2/13/23 17:02	2/9/23	RYTM	Health	Drug	Pharmaceutical Preparations	Cramer Pamela J.	MA	O	CHRO	S.d	-23	27.66	-1	-12	6	D
2/13/23 17:00	2/9/23	RYTM	Health	Drug	Pharmaceutical Preparations	Shulman Joseph	MA	O	Chief Te	M.d	0	0.00	3	999%	3	D
2/13/23 17:00	2/9/23	RYTM	Health	Drug	Pharmaceutical Preparations	Shulman Joseph	MA	O	Chief Te	S.d	-25	27.66	-1	-25	3	D
8/23/22 16:30	8/19/22	RYTM	Health	Drug	Pharmaceutical Preparations	Cramer Pamela J.	MA	O	CHRO	M.d	257	19.02	13		2	D
8/23/22 16:30	8/19/22	RYTM	Health	Drug	Pharmaceutical Preparations	Cramer Pamela J.	MA	O	CHRO	S.d	-335	24.83	-13	-86	2	D
7/28/22 16:31	7/26/22	RYTM	Health	Drug	Pharmaceutical Preparations	Cramer Pamela J.	MA	O	CHRO	M.d	0	0.00	3		2	D
7/28/22 16:31	7/27/22	RYTM	Health	Drug	Pharmaceutical Preparations	Cramer Pamela J.	MA	O	CHRO	S.d	-11	11.68	-1	-29	2	D
7/6/22 18:08	6/30/22	RYTM	Health	Drug	Pharmaceutical Preparations	Smith Hunter C	MA	O	CFO	M.d	0	0.00	25	77	58	D
7/6/22 18:08	7/1/22	RYTM	Health	Drug	Pharmaceutical Preparations	Smith Hunter C	MA	O	CFO	S.d	-31	4.08	-8	-12	58	D
3/31/22 16:31	3/29/22	RYTM	Health	Drug	Pharmaceutical Preparations	Roberts William T.	MA	O	Chief Ac	M.d	0	0.00	3		1	D
3/31/22 16:31	3/29/22	RYTM	Health	Drug	Pharmaceutical Preparations	Roberts William T.	MA	O	Chief Ac	S.d	-11	11.13	-1	-41	1	D
2/15/22 19:32	2/11/22	RYTM	Health	Drug	Pharmaceutical Preparations	Shulman Joseph	MA	O	Chief Te	M.d	0	0.00	2		1	D
2/15/22 19:32	2/15/22	RYTM	Health	Drug	Pharmaceutical Preparations	Shulman Joseph	MA	O	Chief Te	S.d	-3	6.10	-1	-36	1	D
2/15/22 19:31	2/11/22	RYTM	Health	Drug	Pharmaceutical Preparations	Smith Hunter C	MA	O	CFO	M.d	0	0.00	2	6	40	D
2/15/22 19:31	2/15/22	RYTM	Health	Drug	Pharmaceutical Preparations	Smith Hunter C	MA	O	CFO	S.d	-5	6.10	-1	-2	40	D
2/15/22 19:29	2/11/22	RYTM	Health	Drug	Pharmaceutical Preparations	Mazabraud Yann	MA	O	EVP,Head	M.d	0	0.00	2		1	D
2/15/22 19:29	2/15/22	RYTM	Health	Drug	Pharmaceutical Preparations	Mazabraud Yann	MA	O	EVP,Head	S.d	-6	6.10	-1	-46	1	D
2/15/22 19:28	2/11/22	RYTM	Health	Drug	Pharmaceutical Preparations	Chien Jennifer	MA	O	EVP,Head	M.d	0	0.00	2		1	D
2/15/22 19:28	2/15/22	RYTM	Health	Drug	Pharmaceutical Preparations	Chien Jennifer	MA	O	EVP,Head	S.d	-4	6.10	-1	-36	1	D
4/23/21 06:08	4/21/21	RYTM	Health	Drug	Pharmaceutical Preparations	Smith Hunter C	MA	O	CFO	M.d	34	6.88	5	15	39	D
3/31/21 16:08	3/30/21	RYTM	Health	Drug	Pharmaceutical Preparations	Meeker David P	MA	DO	P,CEO	P	202	20.17	10	10	111	D
3/16/21 17:13	3/15/21	RYTM	Health	Drug	Pharmaceutical Preparations	Foley Todd	MA	D		S	-25,100	25.10	-1,000	-52	909	I
1/20/21 16:05	1/19/21	RYTM	Health	Drug	Pharmaceutical Preparations	Smith Hunter C	MA	O	CFO	M.d	28	6.88	4	13	34	D
12/4/20 16:30	12/2/20	RYTM	Health	Drug	Pharmaceutical Preparations	Ra Capital Management, L.P.	MA	H	Former 1	S.m	-7,030	29.47	-239	-5	4,361	I
9/1/20 16:05	8/31/20	RYTM	Health	Drug	Pharmaceutical Preparations	Desikan Nithya	MA	O	Chief Co	M.d	172	6.88	25	134	44	D
9/1/20 16:05	8/31/20	RYTM	Health	Drug	Pharmaceutical Preparations	Desikan Nithya	MA	O	Chief Co	S.d	-750	30.00	-25	-36	44	D
8/13/20 16:05	8/11/20	RYTM	Health	Drug	Pharmaceutical Preparations	Desikan Nithya	MA	O	Chief Co	M.d	100	6.88	15	50	44	D
7/2/20 16:46	6/30/20	RYTM	Health	Drug	Pharmaceutical Preparations	Ra Capital Management, L.P.	MA	T		S.m	-2,903	22.06	-132	-2	5,140	I
6/30/20 16:35	6/26/20	RYTM	Health	Drug	Pharmaceutical Preparations	Foley Todd	MA	D		S	-8	25.04	0	0	1,909	I
6/29/20 18:31	6/25/20	RYTM	Health	Drug	Pharmaceutical Preparations	Ra Capital Management, L.P.	MA	T		S.m	-3,466	23.05	-150	-3	5,272	I
6/25/20 17:38	6/24/20	RYTM	Health	Drug	Pharmaceutical Preparations	Foley Todd	MA	D		S.m	-2,924	25.35	-115	-6	1,910	I
6/5/20 16:16	6/5/20	RYTM	Health	Drug	Pharmaceutical Preparations	Foley Todd	MA	D		S	-38	20.00	-2	0	2,025	I
6/3/20 17:08	6/1/20	RYTM	Health	Drug	Pharmaceutical Preparations	Foley Todd	MA	D		S.m	-897	20.21	-44	-2	2,027	I
5/28/20 18:39	5/27/20	RYTM	Health	Drug	Pharmaceutical Preparations	Foley Todd	MA	D		S.m	-591	20.17	-29	-1	2,071	I
5/26/20 17:14	5/21/20	RYTM	Health	Drug	Pharmaceutical Preparations	Foley Todd	MA	D		S.m	-1,969	20.32	-97	-4	2,100	I
5/20/20 17:48	5/18/20	RYTM	Health	Drug	Pharmaceutical Preparations	Foley Todd	MA	D		S.m	-690	20.00	-35	-2	2,197	I
5/15/20 17:59	5/13/20	RYTM	Health	Drug	Pharmaceutical Preparations	Foley Todd	MA	D		S	-37	20.04	-2	0	2,232	I
5/12/20 17:28	5/8/20	RYTM	Health	Drug	Pharmaceutical Preparations	Foley Todd	MA	D		S.m	-1,076	20.25	-53	-2	2,234	I
5/7/20 17:02	5/6/20	RYTM	Health	Drug	Pharmaceutical Preparations	Foley Todd	MA	D		S.m	-37	20.00	-2	0	2,287	I
4/30/20 16:45	4/28/20	RYTM	Health	Drug	Pharmaceutical Preparations	Foley Todd	MA	D		S.m	-728	20.10	-36	-2	2,289	I
4/1/20 16:20	3/31/20	RYTM	Health	Drug	Pharmaceutical Preparations	Foley Todd	MA	D		S.m	-523	15.13	-35	-1	2,325	I
3/31/20 18:00	3/30/20	RYTM	Health	Drug	Pharmaceutical Preparations	Smith Hunter C	MA	O	CFO,Inte	M.d	27	6.88	4	15	30	D
3/30/20 16:57	3/26/20	RYTM	Health	Drug	Pharmaceutical Preparations	Foley Todd	MA	D		S	-35	15.04	-2	0	2,359	I
3/24/20 16:58	3/20/20	RYTM	Health	Drug	Pharmaceutical Preparations	Foley Todd	MA	D		S	-17	15.00	-1	0	2,362	I
3/19/20 17:04	3/17/20	RYTM	Health	Drug	Pharmaceutical Preparations	Foley Todd	MA	D		S.m	-463	15.12	-31	-1	2,363	I
3/16/20 16:16	3/13/20	RYTM	Health	Drug	Pharmaceutical Preparations	Smith Hunter C	MA	O	CFO	M.d	24	6.88	4	16	26	D
3/11/20 16:01	3/9/20	RYTM	Health	Drug	Pharmaceutical Preparations	Gottesdiener Keith Michael	MA	DO	CEO,P	M.d	21	6.14	3	1	558	D
2/12/20 16:00	2/10/20	RYTM	Health	Drug	Pharmaceutical Preparations	Gottesdiener Keith Michael	MA	DO	CEO,P	M.d	42	6.14	7	1	554	D
1/29/20 16:00	1/28/20	RYTM	Health	Drug	Pharmaceutical Preparations	Smith Hunter C	MA	O	CFO	M.d	43	6.88	6	39	22	D
1/10/20 16:01	1/8/20	RYTM	Health	Drug	Pharmaceutical Preparations	Gottesdiener Keith Michael	MA	DO	CEO,P	M.d	152	4.59	33	6	547	D
12/31/19 16:02	12/27/19	RYTM	Health	Drug	Pharmaceutical Preparations	Desikan Nithya	MA	O	Chief Co	M.d	242	6.88	35		29	D
12/31/19 16:02	12/27/19	RYTM	Health	Drug	Pharmaceutical Preparations	Desikan Nithya	MA	O	Chief Co	S.d	-802	22.79	-35	-55	29	D
12/13/19 16:25	12/11/19	RYTM	Health	Drug	Pharmaceutical Preparations	Foley Todd	MA	D		S.m	-436	25.11	-17	-1	2,393	I
12/11/19 16:13	12/9/19	RYTM	Health	Drug	Pharmaceutical Preparations	Foley Todd	MA	D		S.m	-1,617	25.25	-64	-3	2,411	I
12/3/19 20:05	12/2/19	RYTM	Health	Drug	Pharmaceutical Preparations	Foley Todd	MA	D		S.m	-933	22.15	-42	-2	2,475	I
11/29/19 14:40	11/26/19	RYTM	Health	Drug	Pharmaceutical Preparations	Foley Todd	MA	D		S.m	-2,947	23.11	-128	-5	2,517	I
11/26/19 16:22	11/22/19	RYTM	Health	Drug	Pharmaceutical Preparations	Foley Todd	MA	D		S.m	-5,048	22.53	-224	-8	2,645	I
11/22/19 17:30	11/20/19	RYTM	Health	Drug	Pharmaceutical Preparations	Foley Todd	MA	D		S.m	-4,447	21.56	-206	-7	2,869	I
8/13/19 16:04	8/12/19	RYTM	Health	Drug	Pharmaceutical Preparations	Desikan Nithya	MA	O	Chief Co	M.d	100	6.88	15	100	29	D
7/17/19 16:11	7/16/19	RYTM	Health	Drug	Pharmaceutical Preparations	Gottesdiener Keith Michael	MA	DO	CEO,P	M.d	34	4.59	8	1	514	D
7/15/19 16:01	7/11/19	RYTM	Health	Drug	Pharmaceutical Preparations	Smith Hunter C	MA	O	CFO	M.d	69	6.88	10	167	16	D
6/3/19 16:00	5/30/19	RYTM	Health	Drug	Pharmaceutical Preparations	Van Der Ploeg Leonardus H.T.	MA	O	Chief Sc	M.dm	46	4.59	10	31	42	D
6/3/19 16:00	5/30/19	RYTM	Health	Drug	Pharmaceutical Preparations	Van Der Ploeg Leonardus H.T.	MA	O	Chief Sc	S.dm	-252	25.21	-10	-19	42	D
5/30/19 16:01	5/28/19	RYTM	Health	Drug	Pharmaceutical Preparations	Van Der Ploeg Leonardus H.T.	MA	O	Chief Sc	M.dm	69	4.60	15	55	42	D
5/30/19 16:01	5/28/19	RYTM	Health	Drug	Pharmaceutical Preparations	Van Der Ploeg Leonardus H.T.	MA	O	Chief Sc	S.dm	-381	25.42	-15	-26	42	D
3/19/19 16:25	3/15/19	RYTM	Health	Drug	Pharmaceutical Preparations	Gottesdiener Keith Michael	MA	DO	CEO,P	S.m	-310	30.09	-10	-2	506	D
3/15/19 16:01	3/13/19	RYTM	Health	Drug	Pharmaceutical Preparations	Gottesdiener Keith Michael	MA	DO	CEO,P	S.m	-279	30.06	-9	-2	517	D
2/28/19 16:01	2/26/19	RYTM	Health	Drug	Pharmaceutical Preparations	Gottesdiener Keith Michael	MA	DO	CEO,P	S.m	-74	30.04	-2	0	526	D
2/20/19 16:01	2/15/19	RYTM	Health	Drug	Pharmaceutical Preparations	Gottesdiener Keith Michael	MA	DO	CEO,P	S.m	-388	30.02	-13	-2	528	D
2/15/19 16:09	2/13/19	RYTM	Health	Drug	Pharmaceutical Preparations	Gottesdiener Keith Michael	MA	DO	CEO,P	S.d	-118	30.00	-4	-1	541	D
2/4/19 16:01	1/31/19	RYTM	Health	Drug	Pharmaceutical Preparations	Smith Hunter C	MA	O	CFO	M.d	21	6.88	3	100	6	D
1/24/19 16:03	1/22/19	RYTM	Health	Drug	Pharmaceutical Preparations	Gottesdiener Keith Michael	MA	DO	CEO,P	S.m	-474	30.05	-16	-3	545	D
1/22/19 16:07	1/18/19	RYTM	Health	Drug	Pharmaceutical Preparations	Gottesdiener Keith Michael	MA	DO	CEO,P	S	-304	30.01	-10	-2	561	D
1/18/19 16:02	1/16/19	RYTM	Health	Drug	Pharmaceutical Preparations	Van Der Ploeg Leonardus H.T.	MA	O	Chief Sc	S	-6	30.00	0	0	42	D
1/17/19 18:13	1/16/19	RYTM	Health	Drug	Pharmaceutical Preparations	Gottesdiener Keith Michael	MA	DO	CEO,P	S	-20	30.00	-1	0	571	D
12/6/18 16:03	12/3/18	RYTM	Health	Drug	Pharmaceutical Preparations	Gottesdiener Keith Michael	MA	DO	CEO,P	S	-17	30.00	-1	0	571	D
11/6/18 17:21	11/2/18	RYTM	Health	Drug	Pharmaceutical Preparations	Gottesdiener Keith Michael	MA	DO	CEO,P	S	-496	30.08	-17	-3	572	D
11/6/18 17:20	11/2/18	RYTM	Health	Drug	Pharmaceutical Preparations	Van Der Ploeg Leonardus H.T.	MA	O	Chief Sc	M.d	174	6.18	28	197	43	D
11/6/18 17:20	11/2/18	RYTM	Health	Drug	Pharmaceutical Preparations	Van Der Ploeg Leonardus H.T.	MA	O	Chief Sc	S.d	-1,143	30.09	-38	-47	43	D
9/27/18 16:02	9/25/18	RYTM	Health	Drug	Pharmaceutical Preparations	Van Der Ploeg Leonardus H.T.	MA	O	Chief Sc	M.d	100	4.59	22	71	52	D
9/27/18 16:02	9/25/18	RYTM	Health	Drug	Pharmaceutical Preparations	Van Der Ploeg Leonardus H.T.	MA	O	Chief Sc	S.d	-948	29.80	-32	-38	52	D
9/6/18 16:02	9/5/18	RYTM	Health	Drug	Pharmaceutical Preparations	Smith Hunter C	MA	O	CFO	M.d	21	6.88	3	New	3	D
8/14/18 16:01	8/10/18	RYTM	Health	Drug	Pharmaceutical Preparations	Desikan Nithya	MA	O	Chief Co	M.d	100	6.88	15	New	15	D
5/24/18 16:13	5/22/18	RYTM	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	TH	See Rema	S	-596	30.43	-20	-1	2,750	I
5/21/18 18:15	5/18/18	RYTM	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T		S.m	-4,065	30.88	-132	-5	2,770	I
5/10/18 16:08	5/9/18	RYTM	Health	Drug	Pharmaceutical Preparations	Gottesdiener Keith Michael	MA	DO	C.E.O.,P	M.d	14	4.59	3	1	589	D
10/11/17 14:25	10/10/17	RYTM	Health	Drug	Pharmaceutical Preparations	Mpm Bioventures V, L.P.	MA	T		P.d	1,700	17.00	100	4	2,696	I
10/11/17 14:24	10/10/17	RYTM	Health	Drug	Pharmaceutical Preparations	Foley Todd	MA	DT		P.d	1,700	17.00	100	4	2,696	I
10/10/17 16:36	10/10/17	RYTM	Health	Drug	Pharmaceutical Preparations	Viswanathan Ravi	MD	T		P.d	9,350	17.00	550	13	4,910	I
10/10/17 16:35	10/10/17	RYTM	Health	Drug	Pharmaceutical Preparations	Sandell Scott D	MD	T		P.d	9,350	17.00	550	13	4,910	I
10/10/17 16:35	10/10/17	RYTM	Health	Drug	Pharmaceutical Preparations	Mott David M	MD	T		P.d	9,350	17.00	550	13	4,910	I
10/10/17 16:34	10/10/17	RYTM	Health	Drug	Pharmaceutical Preparations	Kerins Patrick J	MD	T		P.d	9,350	17.00	550	13	4,910	I
10/10/17 16:34	10/10/17	RYTM	Health	Drug	Pharmaceutical Preparations	Baskett Forest	MD	T		P.d	9,350	17.00	550	13	4,910	I
10/10/17 16:33	10/10/17	RYTM	Health	Drug	Pharmaceutical Preparations	Barris Peter J	MD	T		P.d	9,350	17.00	550	13	4,910	I
10/10/17 16:33	10/10/17	RYTM	Health	Drug	Pharmaceutical Preparations	Barrett M James	MD	T		P.d	9,350	17.00	550	13	4,910	I
10/10/17 16:32	10/10/17	RYTM	Health	Drug	Pharmaceutical Preparations	New Enterprise Associates 13 LP	MD	T		P.d	9,350	17.00	550	13	4,910	D
10/10/17 16:24	10/10/17	RYTM	Health	Drug	Pharmaceutical Preparations	Meeker David P	MA	D		P.d	425	17.00	25	33	101	D
10/10/17 16:22	10/10/17	RYTM	Health	Drug	Pharmaceutical Preparations	Pfizer Inc	NY	T		P.d	680	17.00	40	3	1,428	D
10/10/17 16:22	10/10/17	RYTM	Health	Drug	Pharmaceutical Preparations	Ipsen, S.A.	I0	T		P.d	340	17.00	20	1	1,646	I
10/10/17 16:21	10/10/17	RYTM	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T		P.d	6,035	17.00	355	14	2,901	I
10/10/17 09:40	10/10/17	RYTM	Health	Drug	Pharmaceutical Preparations	Flynn James E	NY	TH	Possible	P.d	6,035	17.00	355	61	937	I
10/6/17 15:58	10/5/17	RYTM	Health	Drug	Pharmaceutical Preparations	Baker Bros. Advisors LP	NY	H	Former 1	P.d	15,045	17.00	885	89	1,878	I

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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