Bennett C Frank - Insider Stock Trading

TC	Stat	Stk	Ins	Fil	+d	+w	+m	+q	+h	+y	avg
S	%ret	1	1	44	-1	-0	-3	2	6	26	5
S	%wins				64	60	67	48	61	34	56

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	Title	T	TVal	Price	L	Qty	oc	Own	H	r2y	r1y	r6m	r3m	r6w	r3w	r7d	r3d	f1d	f1w	f1m	f3m	f6m	f1y
2/2/24 19:54	2/2/24	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	EVP,Chie	S	-92	49.52	0	-2	-2	79	D
1/18/24 17:44	1/16/24	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	EVP,Chie	M.d	0	0.00	0	18	31	77	D
1/18/24 17:44	1/17/24	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	EVP,Chie	S.d	-340	50.42	0	-7	-8	77	D
12/22/23 19:11	12/20/23	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	EVP,Chie	M.dm	1,070	47.34	0	23	52	66	D
12/22/23 19:11	12/20/23	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	EVP,Chie	S.dm	-1,117	49.39	0	-23	-26	66	D
12/18/23 16:55	12/14/23	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	EVP,Chie	M.d	1,070	47.34	0	23	52	66	D
12/18/23 16:55	12/14/23	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	EVP,Chie	S.d	-1,121	49.58	0	-23	-26	66	D
9/29/23 17:20	9/28/23	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	EVP,Chie	S	-207	46.50	0	-4	-6	66	D
2/7/23 17:36	2/6/23	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	EVP,Chie	S	-74	40.57	0	-2	-3	70	D
1/19/23 20:19	1/17/23	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	EVP,Chie	M.d	0	0.00	0	19	40	68	D
1/19/23 20:19	1/18/23	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	EVP,Chie	S.d	-271	38.89	0	-7	-9	68	D
1/20/22 20:21	1/18/22	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	EVP,Chie	M.d	0	0.00	0	19	52	55	D
1/20/21 19:08	1/15/21	IONS	Ionis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	Chief Sc	M.d	0	0.00	0	16	58	43	D
12/8/20 20:49	12/4/20	IONS	Ionis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	Chief Sc	M.d	317	39.87	0	8	32	32	D
12/8/20 20:49	12/4/20	IONS	Ionis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	Chief Sc	S.d	-406	51.04	0	-8	-20	32	D
12/4/20 20:53	12/2/20	IONS	Ionis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	Chief Sc	M.d	281	39.87	0	7	28	32	D
12/4/20 20:53	12/2/20	IONS	Ionis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	Chief Sc	S.d	-362	51.32	0	-7	-18	32	D
11/5/20 20:26	11/3/20	IONS	Ionis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	Chief Sc	M.d	598	39.87	0	15	86	32	D
11/5/20 20:26	11/3/20	IONS	Ionis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	Chief Sc	S.d	-702	46.77	0	-15	-32	32	D
6/29/20 21:47	6/25/20	IONS	Ionis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	EVP,Chie	M.d	598	39.87	0	15	86	32	D
6/29/20 21:47	6/25/20	IONS	Ionis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	EVP,Chie	S.d	-897	59.77	0	-15	-32	32	D
1/17/20 18:11	1/15/20	IONS	Ionis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	Chief Sc	M.d	0	0.00	0	12	57	32	D
2/5/19 17:59	2/1/19	IONS	Ionis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	M.d	132	14.69	0	9	58	25	D
2/5/19 17:59	2/1/19	IONS	Ionis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	S.d	-525	58.29	0	-9	-27	25	D
1/17/19 19:39	1/15/19	IONS	Ionis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	M.d	0	0.00	0	8	47	24	D
11/1/18 19:34	11/1/18	IONS	Ionis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	M.d	184	14.69	0	13	181	19	D
11/1/18 19:34	11/1/18	IONS	Ionis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	S.d	-619	49.54	0	-13	-39	19	D
8/9/18 18:34	8/8/18	IONS	Ionis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	M.d	184	14.68	0	13	181	19	D
8/9/18 18:34	8/8/18	IONS	Ionis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	S.d	-563	45.00	0	-13	-39	19	D
5/11/18 21:06	5/11/18	IONS	Ionis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	M.d	91	7.25	0	13	189	19	D
5/11/18 21:06	5/11/18	IONS	Ionis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	S.d	-563	45.00	0	-13	-40	19	D
2/1/18 19:58	2/1/18	IONS	Ionis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	M.ad	91	7.25	0	13	189	19	D
2/1/18 19:58	2/1/18	IONS	Ionis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	S.ad	-656	52.50	0	-13	-40	19	D
1/17/18 21:22	1/15/18	IONS	Ionis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	M.d	0	0.00	0	7	54	19	D
1/17/18 21:22	1/16/18	IONS	Ionis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	S.d	-140	51.76	0	-3	-12	19	D
10/20/17 17:35	10/18/17	IONS	Ionis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	M.d	126	10.29	0	12	439	15	D
10/20/17 17:35	10/18/17	IONS	Ionis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	S.d	-796	65.00	0	-12	-45	15	D
7/26/17 20:03	7/24/17	IONS	Ionis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	M.d	103	10.29	0	10	198	15	D
7/26/17 20:03	7/24/17	IONS	Ionis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	S.d	-593	59.29	0	-10	-40	15	D
3/6/17 19:25	3/3/17	IONS	Ionis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	M.d	51	10.29	33	5	51	15	D	-22	42	84	25	16	20	20	10	-7	-15	-21
3/6/17 19:25	3/3/17	IONS	Ionis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	S.d	-275	55.00	33	-5	-25	15	D	-22	42	84	25	16	20	20	10	-7	-15	-21
1/18/17 18:37	1/15/17	IONS	Ionis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	M.d	0	0.00	33	6	72	15	D	-32	6	68	61	8	-13	-1	-5	-1	-10	0	-10
1/18/17 18:37	1/17/17	IONS	Ionis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	S.d	-112	46.29	33	-2	-14	15	D	-32	6	68	61	8	-13	-1	-5	-1	-10	0	-10
11/14/16 18:51	11/9/16	IONS	Ionis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	M.d	257	11.27	33	23		11	D	-17	-31	30	20	18	54	58	35	1	-6	-3	-1
11/14/16 18:51	11/9/16	IONS	Ionis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	S.d	-857	37.56	33	-23	-68	11	D	-17	-31	30	20	18	54	58	35	1	-6	-3	-1
11/9/16 18:22	11/7/16	IONS	Ionis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	M.d	56	11.27	33	5	86	11	D	-29	-50	-4	-13	-13	13	21	17	7	32	27	25	22
11/9/16 18:22	11/7/16	IONS	Ionis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	S.d	-170	34.00	33	-5	-32	11	D	-29	-50	-4	-13	-13	13	21	17	7	32	27	25	22
1/19/16 20:08	1/15/16	IONS	Ionis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	M.d	0	0.00	33	5	100	11	D	-8	-36	-23	0	-24	-26	-25	-10	5	12	-4	6	-30	13
1/19/16 20:08	1/19/16	IONS	Ionis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	S.d	-87	41.46	33	-2	-17	11	D	-8	-36	-23	0	-24	-26	-25	-10	5	12	-4	6	-30	13
12/17/15 19:23	12/15/15	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	M.dm	114	14.47	33	8		7	D	57	8	-6	8	12	-5	4	10	-1
12/17/15 19:23	12/15/15	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	S.dm	-454	57.41	33	-8	-52	7	D	57	8	-6	8	12	-5	4	10	-1
11/12/15 19:03	11/10/15	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	M.d	72	14.47	33	5	216	7	D	86	21	0	22	52	45	20	12	1	-2	-13
11/12/15 19:03	11/10/15	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	S.d	-320	64.00	33	-5	-41	7	D	86	21	0	22	52	45	20	12	1	-2	-13
11/9/15 19:28	11/6/15	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	M.d	72	14.47	33	5	216	7	D	78	23	-10	11	39	27	9	9	2	-1	-7
11/9/15 19:28	11/6/15	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	S.d	-280	56.00	33	-5	-41	7	D	78	23	-10	11	39	27	9	9	2	-1	-7
3/25/15 16:23	3/23/15	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	M.dm	217	14.47	33	15		7	D	305	59	68	5	11	-3	-3	-11	-2	2	8	2	-21
3/25/15 16:23	3/23/15	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	S.dm	-1,059	70.61	33	-15	-67	7	D	305	59	68	5	11	-3	-3	-11	-2	2	8	2	-21
1/20/15 19:55	1/15/15	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	M.d	0	0.00	33	4	123	7	D	394	45	141	71	32	9	1	-3	-4	1	-10	-10	-24
1/20/15 19:55	1/16/15	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	S.d	-103	67.96	33	-2	-17	7	D	394	45	141	71	32	9	1	-3	-4	1	-10	-10	-24
8/28/14 18:49	8/27/14	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	M.d	77	15.38	33	5		5	D	189	64	-30	31	44	21	10	15	2	-2	0	29	72	29
8/28/14 18:49	8/27/14	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	S.d	-203	40.53	33	-5	-52	5	D	189	64	-30	31	44	21	10	15	2	-2	0	29	72	29
6/25/14 19:47	6/23/14	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	M.d	172	15.38	33	11		4	D	228	27	-13	-17	44	32	8	4	1	-2	-15	11	74	72
6/25/14 19:47	6/23/14	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	S.d	-412	36.78	33	-11	-72	4	D	228	27	-13	-17	44	32	8	4	1	-2	-15	11	74	72
1/17/14 19:41	1/15/14	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	M.d	0	0.00	33	2	95	4	D	528	240	57	40	23	16	22	1	2	3	9	-28	-39	47
1/17/14 19:41	1/16/14	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	S.d	-38	47.08	33	-1	-16	4	D	528	240	57	40	23	16	22	1	2	3	9	-28	-39	47
12/6/13 19:39	12/5/13	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	M.d	154	15.38	33	10		3	D	440	334	72	41	10	22	7	2	-2	-3	0	26	-20	35
12/6/13 19:39	12/5/13	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	S.d	-399	39.92	33	-10	-78	3	D	440	334	72	41	10	22	7	2	-2	-3	0	26	-20	35
9/23/13 19:36	9/19/13	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	M.d	154	15.38	33	10		3	D	428	147	114	64	28	40	15	13	-2	0	-18	1	12	6
9/23/13 19:36	9/19/13	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	S.d	-350	35.02	33	-10	-78	3	D	428	147	114	64	28	40	15	13	-2	0	-18	1	12	6
9/11/13 19:26	9/9/13	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	M.d	154	15.38	33	10		3	D	327	107	76	34	11	22	22	11	-1	2	3	22	56	27
9/11/13 19:26	9/9/13	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	S.d	-302	30.23	33	-10	-78	3	D	327	107	76	34	11	22	22	11	-1	2	3	22	56	27
5/2/13 19:48	4/30/13	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	M.dm	564	9.41	30	60		2	D	132	162	142	46	21	12	-1	-4	0	-13	-3	30	63	15
5/2/13 19:48	4/30/13	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	S.dm	-1,342	22.38	30	-60	-97	2	D	132	162	142	46	21	12	-1	-4	0	-13	-3	30	63	15
1/17/13 20:40	1/15/13	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	M.d	0	0.00	19	1	49	2	D	41	85	4	11	56	39	32	6	1	-4	2	37	115	239
1/17/13 20:40	1/16/13	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	S.d	-4	14.00	19	0	-13	2	D	41	85	4	11	56	39	32	6	1	-4	2	37	115	239
7/11/12 16:46	7/9/12	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	M.d	72	6.83	12	11		1	D	43	48	87	74	37	23	16	5	5	8	0	-3	4	156
7/11/12 16:46	7/9/12	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	S.d	-142	13.51	12	-11	-89	1	D	43	48	87	74	37	23	16	5	5	8	0	-3	4	156
7/3/12 19:06	7/3/12	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	M.d	41	6.84	9	6		1	D	41	39	79	45	38	26	19	10	0	5	-9	7	-19	132
7/3/12 19:06	7/3/12	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP,Anti	S.d	-77	12.91	9	-6	-82	1	D	41	39	79	45	38	26	19	10	0	5	-9	7	-19	132
12/22/11 17:20	12/21/11	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP	M.d	9	5.80	4	2		0	D	-32	-33	-21	3	-1	-3	0	5	-1	2	12	22	69	44
12/22/11 17:20	12/21/11	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP	S.d	-11	6.92	4	-2	-84	0	D	-32	-33	-21	3	-1	-3	0	5	-1	2	12	22	69	44
12/20/11 21:08	12/16/11	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP	M.dm	32	5.80	4	6		0	D	-32	-34	-23	-1	-18	-3	-2	0	1	0	13	24	60	48
12/20/11 21:08	12/16/11	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP	S.dm	-38	6.82	4	-6	-95	0	D	-32	-34	-23	-1	-18	-3	-2	0	1	0	13	24	60	48
8/5/11 17:40	8/4/11	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP	M.d	53	5.25	4	10		0	D	-60	-18	-15	-17	-17	-19	-14	-14	-9	-16	-13	1	12	56
8/5/11 17:40	8/4/11	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP	S.d	-76	7.62	4	-10	-97	0	D	-60	-18	-15	-17	-17	-19	-14	-14	-9	-16	-13	1	12	56
7/29/11 18:11	7/28/11	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP	S	-9	8.60	4	-1	-77	0	D	-52	-11	-9	-7	-2	-7	-1	0	-1	-14	-18	-8	-5	51
12/29/10 20:09	12/27/10	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP	M.dm	118	9.63	5	12		1	D	-22	-7	7	24	4	7	1	-2	-2	0	-8	-15	-10	-32
12/29/10 20:09	12/27/10	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP	S.dm	-128	10.38	5	-12	-96	1	D	-22	-7	7	24	4	7	1	-2	-2	0	-8	-15	-10	-32
12/27/10 16:09	12/22/10	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP	M.dm	74	9.63	5	8		1	D	-22	-6	6	21	7	10	7	2	-2	-4	-12	-17	-15	-33
12/27/10 16:09	12/22/10	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP	S.dm	-81	10.52	5	-8	-93	1	D	-22	-6	6	21	7	10	7	2	-2	-4	-12	-17	-15	-33
7/26/10 16:35	7/23/10	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP	S	-11	9.60	9	-1	-66	1	D	-39	-44	-13	-10	4	6	0	4	-1	-2	-24	-11	-8	-13
6/30/10 19:47	6/28/10	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP	M.dm	58	5.80	11	10		1	D	-30	-42	-13	-6	0	9	3	3	-4	-3	2	-13	8	-3
6/30/10 19:47	6/28/10	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP	S.dm	-99	9.89	11	-10	-90	1	D	-30	-42	-13	-6	0	9	3	3	-4	-3	2	-13	8	-3
12/17/09 19:15	12/15/09	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP	M.d	6	6.25	16	1		1	D	-35	-16	-34	-33	-19	-9	-3	2	0	12	14	0	-6	3
12/17/09 19:15	12/15/09	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP	S.d	-10	10.03	16	-1	-51	1	D	-35	-16	-34	-33	-19	-9	-3	2	0	12	14	0	-6	3
7/24/09 17:05	7/23/09	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP	M.d	82	6.81	11	12		1	D	66	8	31	11	12	9	13	6	-1	4	-10	-25	-37	-46
7/24/09 17:05	7/23/09	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP	S.d	-204	17.03	11	-12	-92	1	D	66	8	31	11	12	9	13	6	-1	4	-10	-25	-37	-46
4/24/09 17:32	4/22/09	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP	M.d	68	6.81	11	10		1	D	58	-7	12	18	19	2	7	2	-2	-2	-18	9	-17	-33
4/24/09 17:32	4/22/09	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP	S.d	-159	15.92	11	-10	-94	1	D	58	-7	12	18	19	2	7	2	-2	-2	-18	9	-17	-33
4/9/09 17:22	4/7/09	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP	M.d	68	6.81	11	10		1	D	53	-7	9	5	8	9	0	-1	1	1	2	1	-9	-29
4/9/09 17:22	4/7/09	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP	S.d	-146	14.60	11	-10	-94	1	D	53	-7	9	5	8	9	0	-1	1	1	2	1	-9	-29
8/25/08 18:27	8/20/08	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP	M.d	41	6.81	25	6		1	D	161	47	26	46	27	6	-3	2	-1	-1	-10	-35	-23	-10
8/25/08 18:27	8/20/08	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP	S.d	-108	17.97	25	-6	-92	1	D	161	47	26	46	27	6	-3	2	-1	-1	-10	-35	-23	-10
8/19/08 18:12	8/14/08	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP	M.dm	50	6.25	27	8		1	D	184	57	24	45	29	13	16	-2	-1	-1	-15	-22	-23	-15
8/19/08 18:12	8/14/08	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP	S.dm	-154	19.25	27	-8	-94	1	D	184	57	24	45	29	13	16	-2	-1	-1	-15	-22	-23	-15
8/13/08 18:47	8/11/08	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP	M.d	194	12.94	25	15		1	D	196	62	23	46	35	18	8	16	0	-5	-7	-19	-22	-17
8/13/08 18:47	8/11/08	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP	S.d	-274	18.28	25	-15	-97	1	D	196	62	23	46	35	18	8	16	0	-5	-7	-19	-22	-17
4/3/08 18:26	4/1/08	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP	M.d	53	5.25	25	10		0	D	74	65	-1	-4	5	10	2	5	2	4	-20	-9	11	-3
4/3/08 18:26	4/1/08	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	SVP	S.d	-153	15.33	25	-10	-96	0	D	74	65	-1	-4	5	10	2	5	2	4	-20	-9	11	-3
9/21/07 19:29	9/20/07	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	VP	M.d	172	12.31	23	14		0	D	170	93	41	51	23	19	12	3	-2	3	14	6	0	15
9/21/07 19:29	9/20/07	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	VP	S.d	-207	14.76	23	-14	-99	0	D	170	93	41	51	23	19	12	3	-2	3	14	6	0	15
9/18/07 17:11	9/14/07	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	VP	M.d	52	5.15	22	10		0	D	177	96	54	56	36	12	10	10	2	1	23	15	-2	15
9/18/07 17:11	9/14/07	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	VP	S.d	-138	13.76	22	-10	-98	0	D	177	96	54	56	36	12	10	10	2	1	23	15	-2	15
8/23/07 17:36	8/21/07	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	VP	M.d	63	6.25	19	10		0	D	150	82	29	27	6	26	10	7	1	-2	18	35	11	42
8/23/07 17:36	8/21/07	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	VP	S.d	-125	12.50	19	-10	-98	0	D	150	82	29	27	6	26	10	7	1	-2	18	35	11	42
7/10/07 18:22	7/9/07	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	VP	M.d	24	5.15	16	5		0	D	196	101	4	17	19	31	22	18	-2	-4	-8	37	25	24
7/10/07 18:22	7/9/07	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	VP	S.d	-61	10.65	16	-6	-97	0	D	196	101	4	17	19	31	22	18	-2	-4	-8	37	25	24
11/13/06 20:26	11/9/06	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	VP	M.dm	103	5.15	9	20		1	D	132	107	30	68	44	21	26	14	-11	-18	-4	-26	-27	32
11/13/06 20:26	11/9/06	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	VP	S.dm	-235	11.75	9	-20	-96	1	D	132	107	30	68	44	21	26	14	-11	-18	-4	-26	-27	32
5/9/06 19:58	5/5/06	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	VP	M.d	49	5.80	9	9		0										0	-2	-14	-21	0	25
5/9/06 19:58	5/5/06	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	VP	S.d	-73	8.56	9	-9	-96	0										0	-2	-14	-21	0	25
2/10/06 17:06	2/9/06	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	VP	S	-10	6.50	3	-2	-82	0										0	23	20	24	-1	56
1/22/04 18:08	1/21/04	ISIS	Isis Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	VP	S.a	-8	8.12	5	-1	-64	1	D		16	60	34	56	25	15	13	2	9	-2	-5	-43	-39

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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