9/4/24 20:42 | 2/2/24 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | EVP,Chie | S.a | -93 | 49.52 | 0 | -2 | -2 | 79 | D | | | | | | | | | | | | | | |
2/2/24 19:54 | 2/2/24 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | EVP,Chie | S | -92 | 49.52 | 0 | -2 | -2 | 79 | D | | | | | | | | | | | | | | |
1/18/24 17:44 | 1/16/24 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | EVP,Chie | M.d | 0 | 0.00 | 0 | 18 | 31 | 77 | D | | | | | | | | | | | | | | |
1/18/24 17:44 | 1/17/24 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | EVP,Chie | S.d | -340 | 50.42 | 0 | -7 | -8 | 77 | D | | | | | | | | | | | | | | |
12/22/23 19:11 | 12/20/23 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | EVP,Chie | M.dm | 1,070 | 47.34 | 0 | 23 | 52 | 66 | D | | | | | | | | | | | | | | |
12/22/23 19:11 | 12/20/23 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | EVP,Chie | S.dm | -1,117 | 49.39 | 0 | -23 | -26 | 66 | D | | | | | | | | | | | | | | |
12/18/23 16:55 | 12/14/23 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | EVP,Chie | M.d | 1,070 | 47.34 | 0 | 23 | 52 | 66 | D | | | | | | | | | | | | | | |
12/18/23 16:55 | 12/14/23 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | EVP,Chie | S.d | -1,121 | 49.58 | 0 | -23 | -26 | 66 | D | | | | | | | | | | | | | | |
9/29/23 17:20 | 9/28/23 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | EVP,Chie | S | -207 | 46.50 | 0 | -4 | -6 | 66 | D | | | | | | | | | | | | | | |
2/7/23 17:36 | 2/6/23 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | EVP,Chie | S | -74 | 40.57 | 0 | -2 | -3 | 70 | D | | | | | | | | | | | | | | |
1/19/23 20:19 | 1/17/23 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | EVP,Chie | M.d | 0 | 0.00 | 0 | 19 | 40 | 68 | D | | | | | | | | | | | | | | |
1/19/23 20:19 | 1/18/23 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | EVP,Chie | S.d | -271 | 38.89 | 0 | -7 | -9 | 68 | D | | | | | | | | | | | | | | |
1/20/22 20:21 | 1/18/22 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | EVP,Chie | M.d | 0 | 0.00 | 0 | 19 | 52 | 55 | D | | | | | | | | | | | | | | |
1/20/21 19:08 | 1/15/21 | IONS | Ionis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | Chief Sc | M.d | 0 | 0.00 | 0 | 16 | 58 | 43 | D | | | | | | | | | | | | | | |
12/8/20 20:49 | 12/4/20 | IONS | Ionis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | Chief Sc | M.d | 317 | 39.87 | 0 | 8 | 32 | 32 | D | | | | | | | | | | | | | | |
12/8/20 20:49 | 12/4/20 | IONS | Ionis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | Chief Sc | S.d | -406 | 51.04 | 0 | -8 | -20 | 32 | D | | | | | | | | | | | | | | |
12/4/20 20:53 | 12/2/20 | IONS | Ionis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | Chief Sc | M.d | 281 | 39.87 | 0 | 7 | 28 | 32 | D | | | | | | | | | | | | | | |
12/4/20 20:53 | 12/2/20 | IONS | Ionis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | Chief Sc | S.d | -362 | 51.32 | 0 | -7 | -18 | 32 | D | | | | | | | | | | | | | | |
11/5/20 20:26 | 11/3/20 | IONS | Ionis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | Chief Sc | M.d | 598 | 39.87 | 0 | 15 | 86 | 32 | D | | | | | | | | | | | | | | |
11/5/20 20:26 | 11/3/20 | IONS | Ionis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | Chief Sc | S.d | -702 | 46.77 | 0 | -15 | -32 | 32 | D | | | | | | | | | | | | | | |
6/29/20 21:47 | 6/25/20 | IONS | Ionis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | EVP,Chie | M.d | 598 | 39.87 | 0 | 15 | 86 | 32 | D | | | | | | | | | | | | | | |
6/29/20 21:47 | 6/25/20 | IONS | Ionis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | EVP,Chie | S.d | -897 | 59.77 | 0 | -15 | -32 | 32 | D | | | | | | | | | | | | | | |
1/17/20 18:11 | 1/15/20 | IONS | Ionis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | Chief Sc | M.d | 0 | 0.00 | 0 | 12 | 57 | 32 | D | | | | | | | | | | | | | | |
2/5/19 17:59 | 2/1/19 | IONS | Ionis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | M.d | 132 | 14.69 | 0 | 9 | 58 | 25 | D | | | | | | | | | | | | | | |
2/5/19 17:59 | 2/1/19 | IONS | Ionis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | S.d | -525 | 58.29 | 0 | -9 | -27 | 25 | D | | | | | | | | | | | | | | |
1/17/19 19:39 | 1/15/19 | IONS | Ionis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | M.d | 0 | 0.00 | 0 | 8 | 47 | 24 | D | | | | | | | | | | | | | | |
11/1/18 19:34 | 11/1/18 | IONS | Ionis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | M.d | 184 | 14.69 | 0 | 13 | 181 | 19 | D | | | | | | | | | | | | | | |
11/1/18 19:34 | 11/1/18 | IONS | Ionis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | S.d | -619 | 49.54 | 0 | -13 | -39 | 19 | D | | | | | | | | | | | | | | |
8/9/18 18:34 | 8/8/18 | IONS | Ionis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | M.d | 184 | 14.68 | 0 | 13 | 181 | 19 | D | | | | | | | | | | | | | | |
8/9/18 18:34 | 8/8/18 | IONS | Ionis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | S.d | -563 | 45.00 | 0 | -13 | -39 | 19 | D | | | | | | | | | | | | | | |
5/11/18 21:06 | 5/11/18 | IONS | Ionis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | M.d | 91 | 7.25 | 0 | 13 | 189 | 19 | D | | | | | | | | | | | | | | |
5/11/18 21:06 | 5/11/18 | IONS | Ionis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | S.d | -563 | 45.00 | 0 | -13 | -40 | 19 | D | | | | | | | | | | | | | | |
2/1/18 19:58 | 2/1/18 | IONS | Ionis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | M.ad | 91 | 7.25 | 0 | 13 | 189 | 19 | D | | | | | | | | | | | | | | |
2/1/18 19:58 | 2/1/18 | IONS | Ionis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | S.ad | -656 | 52.50 | 0 | -13 | -40 | 19 | D | | | | | | | | | | | | | | |
1/17/18 21:22 | 1/15/18 | IONS | Ionis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | M.d | 0 | 0.00 | 0 | 7 | 54 | 19 | D | | | | | | | | | | | | | | |
1/17/18 21:22 | 1/16/18 | IONS | Ionis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | S.d | -140 | 51.76 | 0 | -3 | -12 | 19 | D | | | | | | | | | | | | | | |
10/20/17 17:35 | 10/18/17 | IONS | Ionis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | M.d | 126 | 10.29 | 0 | 12 | 439 | 15 | D | | | | | | | | | | | | | | |
10/20/17 17:35 | 10/18/17 | IONS | Ionis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | S.d | -796 | 65.00 | 0 | -12 | -45 | 15 | D | | | | | | | | | | | | | | |
7/26/17 20:03 | 7/24/17 | IONS | Ionis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | M.d | 103 | 10.29 | 0 | 10 | 198 | 15 | D | | | | | | | | | | | | | | |
7/26/17 20:03 | 7/24/17 | IONS | Ionis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | S.d | -593 | 59.29 | 0 | -10 | -40 | 15 | D | | | | | | | | | | | | | | |
3/6/17 19:25 | 3/3/17 | IONS | Ionis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | M.d | 51 | 10.29 | 33 | 5 | 51 | 15 | D | -22 | 42 | 84 | 25 | 16 | 20 | 20 | 10 | -7 | -15 | -21 | | | |
3/6/17 19:25 | 3/3/17 | IONS | Ionis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | S.d | -275 | 55.00 | 33 | -5 | -25 | 15 | D | -22 | 42 | 84 | 25 | 16 | 20 | 20 | 10 | -7 | -15 | -21 | | | |
1/18/17 18:37 | 1/15/17 | IONS | Ionis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | M.d | 0 | 0.00 | 33 | 6 | 72 | 15 | D | -32 | 6 | 68 | 61 | 8 | -13 | -1 | -5 | -1 | -10 | 0 | -10 | | |
1/18/17 18:37 | 1/17/17 | IONS | Ionis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | S.d | -112 | 46.29 | 33 | -2 | -14 | 15 | D | -32 | 6 | 68 | 61 | 8 | -13 | -1 | -5 | -1 | -10 | 0 | -10 | | |
11/14/16 18:51 | 11/9/16 | IONS | Ionis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | M.d | 257 | 11.27 | 33 | 23 | | 11 | D | -17 | -31 | 30 | 20 | 18 | 54 | 58 | 35 | 1 | -6 | -3 | -1 | | |
11/14/16 18:51 | 11/9/16 | IONS | Ionis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | S.d | -857 | 37.56 | 33 | -23 | -68 | 11 | D | -17 | -31 | 30 | 20 | 18 | 54 | 58 | 35 | 1 | -6 | -3 | -1 | | |
11/9/16 18:22 | 11/7/16 | IONS | Ionis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | M.d | 56 | 11.27 | 33 | 5 | 86 | 11 | D | -29 | -50 | -4 | -13 | -13 | 13 | 21 | 17 | 7 | 32 | 27 | 25 | 22 | |
11/9/16 18:22 | 11/7/16 | IONS | Ionis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | S.d | -170 | 34.00 | 33 | -5 | -32 | 11 | D | -29 | -50 | -4 | -13 | -13 | 13 | 21 | 17 | 7 | 32 | 27 | 25 | 22 | |
1/19/16 20:08 | 1/15/16 | IONS | Ionis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | M.d | 0 | 0.00 | 33 | 5 | 100 | 11 | D | -8 | -36 | -23 | 0 | -24 | -26 | -25 | -10 | 5 | 12 | -4 | 6 | -30 | 13 |
1/19/16 20:08 | 1/19/16 | IONS | Ionis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | S.d | -87 | 41.46 | 33 | -2 | -17 | 11 | D | -8 | -36 | -23 | 0 | -24 | -26 | -25 | -10 | 5 | 12 | -4 | 6 | -30 | 13 |
12/17/15 19:23 | 12/15/15 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | M.dm | 114 | 14.47 | 33 | 8 | | 7 | D | 57 | 8 | -6 | 8 | 12 | -5 | 4 | 10 | -1 | | | | | |
12/17/15 19:23 | 12/15/15 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | S.dm | -454 | 57.41 | 33 | -8 | -52 | 7 | D | 57 | 8 | -6 | 8 | 12 | -5 | 4 | 10 | -1 | | | | | |
11/12/15 19:03 | 11/10/15 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | M.d | 72 | 14.47 | 33 | 5 | 216 | 7 | D | 86 | 21 | 0 | 22 | 52 | 45 | 20 | 12 | 1 | -2 | -13 | | | |
11/12/15 19:03 | 11/10/15 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | S.d | -320 | 64.00 | 33 | -5 | -41 | 7 | D | 86 | 21 | 0 | 22 | 52 | 45 | 20 | 12 | 1 | -2 | -13 | | | |
11/9/15 19:28 | 11/6/15 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | M.d | 72 | 14.47 | 33 | 5 | 216 | 7 | D | 78 | 23 | -10 | 11 | 39 | 27 | 9 | 9 | 2 | -1 | -7 | | | |
11/9/15 19:28 | 11/6/15 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | S.d | -280 | 56.00 | 33 | -5 | -41 | 7 | D | 78 | 23 | -10 | 11 | 39 | 27 | 9 | 9 | 2 | -1 | -7 | | | |
3/25/15 16:23 | 3/23/15 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | M.dm | 217 | 14.47 | 33 | 15 | | 7 | D | 305 | 59 | 68 | 5 | 11 | -3 | -3 | -11 | -2 | 2 | 8 | 2 | -21 | |
3/25/15 16:23 | 3/23/15 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | S.dm | -1,059 | 70.61 | 33 | -15 | -67 | 7 | D | 305 | 59 | 68 | 5 | 11 | -3 | -3 | -11 | -2 | 2 | 8 | 2 | -21 | |
1/20/15 19:55 | 1/15/15 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | M.d | 0 | 0.00 | 33 | 4 | 123 | 7 | D | 394 | 45 | 141 | 71 | 32 | 9 | 1 | -3 | -4 | 1 | -10 | -10 | -24 | |
1/20/15 19:55 | 1/16/15 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | S.d | -103 | 67.96 | 33 | -2 | -17 | 7 | D | 394 | 45 | 141 | 71 | 32 | 9 | 1 | -3 | -4 | 1 | -10 | -10 | -24 | |
8/28/14 18:49 | 8/27/14 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | M.d | 77 | 15.38 | 33 | 5 | | 5 | D | 189 | 64 | -30 | 31 | 44 | 21 | 10 | 15 | 2 | -2 | 0 | 29 | 72 | 29 |
8/28/14 18:49 | 8/27/14 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | S.d | -203 | 40.53 | 33 | -5 | -52 | 5 | D | 189 | 64 | -30 | 31 | 44 | 21 | 10 | 15 | 2 | -2 | 0 | 29 | 72 | 29 |
6/25/14 19:47 | 6/23/14 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | M.d | 172 | 15.38 | 33 | 11 | | 4 | D | 228 | 27 | -13 | -17 | 44 | 32 | 8 | 4 | 1 | -2 | -15 | 11 | 74 | 72 |
6/25/14 19:47 | 6/23/14 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | S.d | -412 | 36.78 | 33 | -11 | -72 | 4 | D | 228 | 27 | -13 | -17 | 44 | 32 | 8 | 4 | 1 | -2 | -15 | 11 | 74 | 72 |
1/17/14 19:41 | 1/15/14 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | M.d | 0 | 0.00 | 33 | 2 | 95 | 4 | D | 528 | 240 | 57 | 40 | 23 | 16 | 22 | 1 | 2 | 3 | 9 | -28 | -39 | 47 |
1/17/14 19:41 | 1/16/14 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | S.d | -38 | 47.08 | 33 | -1 | -16 | 4 | D | 528 | 240 | 57 | 40 | 23 | 16 | 22 | 1 | 2 | 3 | 9 | -28 | -39 | 47 |
12/6/13 19:39 | 12/5/13 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | M.d | 154 | 15.38 | 33 | 10 | | 3 | D | 440 | 334 | 72 | 41 | 10 | 22 | 7 | 2 | -2 | -3 | 0 | 26 | -20 | 35 |
12/6/13 19:39 | 12/5/13 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | S.d | -399 | 39.92 | 33 | -10 | -78 | 3 | D | 440 | 334 | 72 | 41 | 10 | 22 | 7 | 2 | -2 | -3 | 0 | 26 | -20 | 35 |
9/23/13 19:36 | 9/19/13 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | M.d | 154 | 15.38 | 33 | 10 | | 3 | D | 428 | 147 | 114 | 64 | 28 | 40 | 15 | 13 | -2 | 0 | -18 | 1 | 12 | 6 |
9/23/13 19:36 | 9/19/13 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | S.d | -350 | 35.02 | 33 | -10 | -78 | 3 | D | 428 | 147 | 114 | 64 | 28 | 40 | 15 | 13 | -2 | 0 | -18 | 1 | 12 | 6 |
9/11/13 19:26 | 9/9/13 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | M.d | 154 | 15.38 | 33 | 10 | | 3 | D | 327 | 107 | 76 | 34 | 11 | 22 | 22 | 11 | -1 | 2 | 3 | 22 | 56 | 27 |
9/11/13 19:26 | 9/9/13 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | S.d | -302 | 30.23 | 33 | -10 | -78 | 3 | D | 327 | 107 | 76 | 34 | 11 | 22 | 22 | 11 | -1 | 2 | 3 | 22 | 56 | 27 |
5/2/13 19:48 | 4/30/13 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | M.dm | 564 | 9.41 | 30 | 60 | | 2 | D | 132 | 162 | 142 | 46 | 21 | 12 | -1 | -4 | 0 | -13 | -3 | 30 | 63 | 15 |
5/2/13 19:48 | 4/30/13 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | S.dm | -1,342 | 22.38 | 30 | -60 | -97 | 2 | D | 132 | 162 | 142 | 46 | 21 | 12 | -1 | -4 | 0 | -13 | -3 | 30 | 63 | 15 |
1/17/13 20:40 | 1/15/13 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | M.d | 0 | 0.00 | 19 | 1 | 49 | 2 | D | 41 | 85 | 4 | 11 | 56 | 39 | 32 | 6 | 1 | -4 | 2 | 37 | 115 | 239 |
1/17/13 20:40 | 1/16/13 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | S.d | -4 | 14.00 | 19 | 0 | -13 | 2 | D | 41 | 85 | 4 | 11 | 56 | 39 | 32 | 6 | 1 | -4 | 2 | 37 | 115 | 239 |
7/11/12 16:46 | 7/9/12 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | M.d | 72 | 6.83 | 12 | 11 | | 1 | D | 43 | 48 | 87 | 74 | 37 | 23 | 16 | 5 | 5 | 8 | 0 | -3 | 4 | 156 |
7/11/12 16:46 | 7/9/12 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | S.d | -142 | 13.51 | 12 | -11 | -89 | 1 | D | 43 | 48 | 87 | 74 | 37 | 23 | 16 | 5 | 5 | 8 | 0 | -3 | 4 | 156 |
7/3/12 19:06 | 7/3/12 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | M.d | 41 | 6.84 | 9 | 6 | | 1 | D | 41 | 39 | 79 | 45 | 38 | 26 | 19 | 10 | 0 | 5 | -9 | 7 | -19 | 132 |
7/3/12 19:06 | 7/3/12 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP,Anti | S.d | -77 | 12.91 | 9 | -6 | -82 | 1 | D | 41 | 39 | 79 | 45 | 38 | 26 | 19 | 10 | 0 | 5 | -9 | 7 | -19 | 132 |
12/22/11 17:20 | 12/21/11 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP | M.d | 9 | 5.80 | 4 | 2 | | 0 | D | -32 | -33 | -21 | 3 | -1 | -3 | 0 | 5 | -1 | 2 | 12 | 22 | 69 | 44 |
12/22/11 17:20 | 12/21/11 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP | S.d | -11 | 6.92 | 4 | -2 | -84 | 0 | D | -32 | -33 | -21 | 3 | -1 | -3 | 0 | 5 | -1 | 2 | 12 | 22 | 69 | 44 |
12/20/11 21:08 | 12/16/11 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP | M.dm | 32 | 5.80 | 4 | 6 | | 0 | D | -32 | -34 | -23 | -1 | -18 | -3 | -2 | 0 | 1 | 0 | 13 | 24 | 60 | 48 |
12/20/11 21:08 | 12/16/11 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP | S.dm | -38 | 6.82 | 4 | -6 | -95 | 0 | D | -32 | -34 | -23 | -1 | -18 | -3 | -2 | 0 | 1 | 0 | 13 | 24 | 60 | 48 |
8/5/11 17:40 | 8/4/11 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP | M.d | 53 | 5.25 | 4 | 10 | | 0 | D | -60 | -18 | -15 | -17 | -17 | -19 | -14 | -14 | -9 | -16 | -13 | 1 | 12 | 56 |
8/5/11 17:40 | 8/4/11 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP | S.d | -76 | 7.62 | 4 | -10 | -97 | 0 | D | -60 | -18 | -15 | -17 | -17 | -19 | -14 | -14 | -9 | -16 | -13 | 1 | 12 | 56 |
7/29/11 18:11 | 7/28/11 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP | S | -9 | 8.60 | 4 | -1 | -77 | 0 | D | -52 | -11 | -9 | -7 | -2 | -7 | -1 | 0 | -1 | -14 | -18 | -8 | -5 | 51 |
12/29/10 20:09 | 12/27/10 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP | M.dm | 118 | 9.63 | 5 | 12 | | 1 | D | -22 | -7 | 7 | 24 | 4 | 7 | 1 | -2 | -2 | 0 | -8 | -15 | -10 | -32 |
12/29/10 20:09 | 12/27/10 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP | S.dm | -128 | 10.38 | 5 | -12 | -96 | 1 | D | -22 | -7 | 7 | 24 | 4 | 7 | 1 | -2 | -2 | 0 | -8 | -15 | -10 | -32 |
12/27/10 16:09 | 12/22/10 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP | M.dm | 74 | 9.63 | 5 | 8 | | 1 | D | -22 | -6 | 6 | 21 | 7 | 10 | 7 | 2 | -2 | -4 | -12 | -17 | -15 | -33 |
12/27/10 16:09 | 12/22/10 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP | S.dm | -81 | 10.52 | 5 | -8 | -93 | 1 | D | -22 | -6 | 6 | 21 | 7 | 10 | 7 | 2 | -2 | -4 | -12 | -17 | -15 | -33 |
7/26/10 16:35 | 7/23/10 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP | S | -11 | 9.60 | 9 | -1 | -66 | 1 | D | -39 | -44 | -13 | -10 | 4 | 6 | 0 | 4 | -1 | -2 | -24 | -11 | -8 | -13 |
6/30/10 19:47 | 6/28/10 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP | M.dm | 58 | 5.80 | 11 | 10 | | 1 | D | -30 | -42 | -13 | -6 | 0 | 9 | 3 | 3 | -4 | -3 | 2 | -13 | 8 | -3 |
6/30/10 19:47 | 6/28/10 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP | S.dm | -99 | 9.89 | 11 | -10 | -90 | 1 | D | -30 | -42 | -13 | -6 | 0 | 9 | 3 | 3 | -4 | -3 | 2 | -13 | 8 | -3 |
12/17/09 19:15 | 12/15/09 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP | M.d | 6 | 6.25 | 16 | 1 | | 1 | D | -35 | -16 | -34 | -33 | -19 | -9 | -3 | 2 | 0 | 12 | 14 | 0 | -6 | 3 |
12/17/09 19:15 | 12/15/09 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP | S.d | -10 | 10.03 | 16 | -1 | -51 | 1 | D | -35 | -16 | -34 | -33 | -19 | -9 | -3 | 2 | 0 | 12 | 14 | 0 | -6 | 3 |
7/24/09 17:05 | 7/23/09 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP | M.d | 82 | 6.81 | 11 | 12 | | 1 | D | 66 | 8 | 31 | 11 | 12 | 9 | 13 | 6 | -1 | 4 | -10 | -25 | -37 | -46 |
7/24/09 17:05 | 7/23/09 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP | S.d | -204 | 17.03 | 11 | -12 | -92 | 1 | D | 66 | 8 | 31 | 11 | 12 | 9 | 13 | 6 | -1 | 4 | -10 | -25 | -37 | -46 |
4/24/09 17:32 | 4/22/09 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP | M.d | 68 | 6.81 | 11 | 10 | | 1 | D | 58 | -7 | 12 | 18 | 19 | 2 | 7 | 2 | -2 | -2 | -18 | 9 | -17 | -33 |
4/24/09 17:32 | 4/22/09 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP | S.d | -159 | 15.92 | 11 | -10 | -94 | 1 | D | 58 | -7 | 12 | 18 | 19 | 2 | 7 | 2 | -2 | -2 | -18 | 9 | -17 | -33 |
4/9/09 17:22 | 4/7/09 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP | M.d | 68 | 6.81 | 11 | 10 | | 1 | D | 53 | -7 | 9 | 5 | 8 | 9 | 0 | -1 | 1 | 1 | 2 | 1 | -9 | -29 |
4/9/09 17:22 | 4/7/09 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP | S.d | -146 | 14.60 | 11 | -10 | -94 | 1 | D | 53 | -7 | 9 | 5 | 8 | 9 | 0 | -1 | 1 | 1 | 2 | 1 | -9 | -29 |
8/25/08 18:27 | 8/20/08 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP | M.d | 41 | 6.81 | 25 | 6 | | 1 | D | 161 | 47 | 26 | 46 | 27 | 6 | -3 | 2 | -1 | -1 | -10 | -35 | -23 | -10 |
8/25/08 18:27 | 8/20/08 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP | S.d | -108 | 17.97 | 25 | -6 | -92 | 1 | D | 161 | 47 | 26 | 46 | 27 | 6 | -3 | 2 | -1 | -1 | -10 | -35 | -23 | -10 |
8/19/08 18:12 | 8/14/08 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP | M.dm | 50 | 6.25 | 27 | 8 | | 1 | D | 184 | 57 | 24 | 45 | 29 | 13 | 16 | -2 | -1 | -1 | -15 | -22 | -23 | -15 |
8/19/08 18:12 | 8/14/08 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP | S.dm | -154 | 19.25 | 27 | -8 | -94 | 1 | D | 184 | 57 | 24 | 45 | 29 | 13 | 16 | -2 | -1 | -1 | -15 | -22 | -23 | -15 |
8/13/08 18:47 | 8/11/08 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP | M.d | 194 | 12.94 | 25 | 15 | | 1 | D | 196 | 62 | 23 | 46 | 35 | 18 | 8 | 16 | 0 | -5 | -7 | -19 | -22 | -17 |
8/13/08 18:47 | 8/11/08 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP | S.d | -274 | 18.28 | 25 | -15 | -97 | 1 | D | 196 | 62 | 23 | 46 | 35 | 18 | 8 | 16 | 0 | -5 | -7 | -19 | -22 | -17 |
4/3/08 18:26 | 4/1/08 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP | M.d | 53 | 5.25 | 25 | 10 | | 0 | D | 74 | 65 | -1 | -4 | 5 | 10 | 2 | 5 | 2 | 4 | -20 | -9 | 11 | -3 |
4/3/08 18:26 | 4/1/08 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | SVP | S.d | -153 | 15.33 | 25 | -10 | -96 | 0 | D | 74 | 65 | -1 | -4 | 5 | 10 | 2 | 5 | 2 | 4 | -20 | -9 | 11 | -3 |
9/21/07 19:29 | 9/20/07 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | VP | M.d | 172 | 12.31 | 23 | 14 | | 0 | D | 170 | 93 | 41 | 51 | 23 | 19 | 12 | 3 | -2 | 3 | 14 | 6 | 0 | 15 |
9/21/07 19:29 | 9/20/07 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | VP | S.d | -207 | 14.76 | 23 | -14 | -99 | 0 | D | 170 | 93 | 41 | 51 | 23 | 19 | 12 | 3 | -2 | 3 | 14 | 6 | 0 | 15 |
9/18/07 17:11 | 9/14/07 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | VP | M.d | 52 | 5.15 | 22 | 10 | | 0 | D | 177 | 96 | 54 | 56 | 36 | 12 | 10 | 10 | 2 | 1 | 23 | 15 | -2 | 15 |
9/18/07 17:11 | 9/14/07 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | VP | S.d | -138 | 13.76 | 22 | -10 | -98 | 0 | D | 177 | 96 | 54 | 56 | 36 | 12 | 10 | 10 | 2 | 1 | 23 | 15 | -2 | 15 |
8/23/07 17:36 | 8/21/07 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | VP | M.d | 63 | 6.25 | 19 | 10 | | 0 | D | 150 | 82 | 29 | 27 | 6 | 26 | 10 | 7 | 1 | -2 | 18 | 35 | 11 | 42 |
8/23/07 17:36 | 8/21/07 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | VP | S.d | -125 | 12.50 | 19 | -10 | -98 | 0 | D | 150 | 82 | 29 | 27 | 6 | 26 | 10 | 7 | 1 | -2 | 18 | 35 | 11 | 42 |
7/10/07 18:22 | 7/9/07 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | VP | M.d | 24 | 5.15 | 16 | 5 | | 0 | D | 196 | 101 | 4 | 17 | 19 | 31 | 22 | 18 | -2 | -4 | -8 | 37 | 25 | 24 |
7/10/07 18:22 | 7/9/07 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | VP | S.d | -61 | 10.65 | 16 | -6 | -97 | 0 | D | 196 | 101 | 4 | 17 | 19 | 31 | 22 | 18 | -2 | -4 | -8 | 37 | 25 | 24 |
11/13/06 20:26 | 11/9/06 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | VP | M.dm | 103 | 5.15 | 9 | 20 | | 1 | D | 132 | 107 | 30 | 68 | 44 | 21 | 26 | 14 | -11 | -18 | -4 | -26 | -27 | 32 |
11/13/06 20:26 | 11/9/06 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | VP | S.dm | -235 | 11.75 | 9 | -20 | -96 | 1 | D | 132 | 107 | 30 | 68 | 44 | 21 | 26 | 14 | -11 | -18 | -4 | -26 | -27 | 32 |
5/9/06 19:58 | 5/5/06 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | VP | M.d | 49 | 5.80 | 9 | 9 | | 0 | | | | | | | | | | 0 | -2 | -14 | -21 | 0 | 25 |
5/9/06 19:58 | 5/5/06 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | VP | S.d | -73 | 8.56 | 9 | -9 | -96 | 0 | | | | | | | | | | 0 | -2 | -14 | -21 | 0 | 25 |
2/10/06 17:06 | 2/9/06 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | VP | S | -10 | 6.50 | 3 | -2 | -82 | 0 | | | | | | | | | | 0 | 23 | 20 | 24 | -1 | 56 |
1/22/04 18:08 | 1/21/04 | ISIS | Isis Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | VP | S.a | -8 | 8.12 | 5 | -1 | -64 | 1 | D | | 16 | 60 | 34 | 56 | 25 | 15 | 13 | 2 | 9 | -2 | -5 | -43 | -39 |