Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	Title	T	TVal	Price	Qty	oc	Own	H
8/14/26 21:35	8/10/26	NTRA	Natera, Inc.	DE	Health	Health	Medical Laboratories	Sheena Jonathan	TX	DH	CO-FOUND	S	-1,952	325.32	-6	-2	267	D
8/14/26 20:57	8/14/26	OTLK	Outlook Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Jahr Robert Charles	NJ	DO	CEO	P.d	0	0.00	152	New	152	D
8/14/26 20:46	8/12/26	CUE	Cue Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lin Shao-Lee	MA	DO	CEO	M.d	0	0.00	109	18	706	D
8/14/26 20:46	8/12/26	CUE	Cue Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lin Shao-Lee	MA	DO	CEO	S.dm	-1,607	27.58	-58	-8	706	D
8/14/26 19:52	8/12/26	OTLK	Outlook Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Sukhtian Ghiath M.		DT		P.d	2,500	0.9900	2,525	11	24,617	I
8/14/26 19:39	8/14/26	OTLK	Outlook Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Kenyon Lawrence A	NJ	DO	CFO	P.d	0	0.00	101	999%	107	D
8/14/26 19:25	8/12/26	TECX	Tectonic Therapeutic, Inc.	NY	Health	BioPrd	Biological Products, (No Diag	McNamara Peter	MA	O	Chief Sc	M.d	1	14.71	0	0	55	D
8/14/26 19:25	8/12/26	TECX	Tectonic Therapeutic, Inc.	NY	Health	BioPrd	Biological Products, (No Diag	McNamara Peter	MA	O	Chief Sc	S.d	-2	35.00	0	0	55	D
8/14/26 19:14	8/12/26	IRON	Disc Medicine, Inc.		Health	Drug	Pharmaceutical Preparations	Yu Jonathan Yen-Wen	MA	O	COO	M.d	11	13.50	1	2	54	D
8/14/26 19:14	8/12/26	IRON	Disc Medicine, Inc.		Health	Drug	Pharmaceutical Preparations	Yu Jonathan Yen-Wen	MA	O	COO	S.d	-66	82.64	-1	-1	54	D
8/14/26 19:04	8/13/26	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lee Jennifer Kayden	MA	O	EVP,Head	M.d	997	17.62	57		0	D
8/14/26 19:04	8/13/26	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lee Jennifer Kayden	MA	O	EVP,Head	S.d	-8,902	117.38	-76	-100	0	D
8/14/26 19:01	8/12/26	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mazabraud Yann	MA	O	EVP,Head	M.d	317	6.80	47	516	56	D
8/14/26 19:01	8/12/26	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mazabraud Yann	MA	O	EVP,Head	S.d	-6,621	116.15	-57	-51	56	D
8/14/26 18:22	8/14/26	KRYS	Krystal Biotech, Inc.		Health	BioPrd	Biological Products, (No Diag	Rossi Dino A	PA	D		S	-8,228	329.12	-25	-33	50	D
8/14/26 18:01	8/12/26	MANE	Veradermics, Inc	DE	Health	Drug	Pharmaceutical Preparations	Childs John W	CT	D		S	-10,712	107.12	-100	-5	2,102	I
8/14/26 17:52	8/14/26	ORKA	Oruka Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Quinlan Paul T	CA	O	GC	M.d	603	11.60	52		31	D
8/14/26 17:52	8/14/26	ORKA	Oruka Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Quinlan Paul T	CA	O	GC	S.d	-5,641	108.49	-52	-63	31	D
8/14/26 17:48	8/13/26	LFST	Lifestance Health Group, Inc.	DE	Health	Health	Health Services	Deluca Teresa	AZ	D		S	-250	12.23	-20	-16	105	D
8/14/26 17:44	8/12/26	SEPN	Septerna, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Third Rock Ventures V, L.P.	MA	T		S	-7,400	50.27	-147	-1	10,280	D
8/14/26 17:42	8/13/26	ORKA	Oruka Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Agarwal Arjun	CA	O	SVP,Fina	M.d	157	15.69	10	188	15	D
8/14/26 17:42	8/13/26	ORKA	Oruka Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Agarwal Arjun	CA	O	SVP,Fina	S.d	-1,067	106.66	-10	-40	15	D
8/14/26 17:24	8/14/26	CTTH	Ctt Pharmaceutical Holdings, Inc.	FL	Health	Drug	Pharmaceutical Preparations	Ctt Pharmaceutical Holdings, Inc.	FL	O	CEO	P	0	0.0620	2	0	9,355	D
8/14/26 17:15	8/12/26	PACS	Pacs Group, Inc.	DE	Health	Health	Skilled Nursing Care Faciliti	Jergensen Joshua	UT	O	P,COO	S	-1,824	45.59	-40	-2	2,536	D
8/14/26 17:12	8/12/26	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Khattar Jack A.	MD	DO	P,CEO	M.d	0	0.00	30	1	2,216	D
8/14/26 17:11	8/12/26	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rubin Jonathan	MD	O	SVP,Chie	M.d	0	0.00	1	6	14	D
8/14/26 17:11	8/12/26	SEPN	Septerna, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ra Capital Management, L.P.	MA	DT		S	-63,453	42.50	-1,493	-67	725	I
8/14/26 17:11	8/12/26	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bhatt Padmanabh P.	MD	O	SVP of I	M.d	0	0.00	3	15	19	D
8/14/26 17:10	8/12/26	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mottola Frank	MD	O	SVP,Chie	M.d	0	0.00	2	9	20	D
8/14/26 17:09	8/12/26	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dec Timothy C	MD	O	Senior V	M.d	0	0.00	1	16	9	D
8/14/26 17:05	8/12/26	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Espinoza Octavio	FL	O	CFO	M.d	1,801	56.91	32		28	D
8/14/26 17:05	8/12/26	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Espinoza Octavio	FL	O	CFO	S.d	-9,241	292.07	-32	-53	28	D
8/14/26 17:04	8/12/26	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Haas Jason	FL	D		M.d	316	51.56	6		4	D
8/14/26 17:04	8/12/26	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Haas Jason	FL	D		S.d	-2,090	292.81	-7	-64	4	D
8/14/26 17:00	8/13/26	CGEM	Cullinan Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Michaelson Jennifer	MA	O	Chief Sc	M.d	129	4.30	30	23	163	D
8/14/26 17:00	8/13/26	CGEM	Cullinan Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Michaelson Jennifer	MA	O	Chief Sc	S.d	-608	20.26	-30	-16	163	D
8/14/26 17:00	8/14/26	ACTU	Actuate Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Schmitt Daniel M	TX	DO	P,CEO,Di	M.d	0	0.00	272	41	932	D
8/14/26 16:54	8/13/26	MAZE	Maze Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Bernstein Harold	CA	O	P,R,D,CM	M.d	168	10.42	16		0	D
8/14/26 16:54	8/13/26	MAZE	Maze Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Bernstein Harold	CA	O	P,R,D,CM	S.d	-446	27.61	-16	-100	0	D
8/14/26 16:54	8/12/26	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Donovan Joanne M.	CO	O	CMO	M.d	0	0.00	13		9	D
8/14/26 16:54	8/12/26	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Donovan Joanne M.	CO	O	CMO	S.dm	-413	43.71	-9	-52	9	D
8/14/26 16:53	8/12/26	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Russell Alan J	CO	DO	Chief Sc	M.d	0	0.00	13	69	31	D
8/14/26 16:53	8/12/26	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Russell Alan J	CO	DO	Chief Sc	S.d	-258	43.73	-6	-16	31	D
8/14/26 16:53	8/12/26	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Moore John R	CO	O	GC	M.d	0	0.00	12	240	18	D
8/14/26 16:53	8/12/26	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Moore John R	CO	O	GC	S.d	-220	43.82	-5	-22	18	D
8/14/26 16:53	8/12/26	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Derakhshan Behrad	CO	O	Chief Bu	M.d	0	0.00	13	72	32	D
8/14/26 16:53	8/12/26	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Derakhshan Behrad	CO	O	Chief Bu	S.d	-223	43.81	-5	-14	32	D
8/14/26 16:52	8/12/26	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Koch Kevin	CO	DO	P,CEO	M.d	0	0.00	40	315	52	D
8/14/26 16:52	8/12/26	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Koch Kevin	CO	DO	P,CEO	S.d	-785	43.68	-18	-26	52	D
8/14/26 16:41	8/13/26	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	M.d	1,286	135.42	10	1	669	I
8/14/26 16:41	8/13/26	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	S.d	-4,790	504.24	-10	-1	669	I
8/14/26 16:36	8/13/26	BDX	Becton Dickinson & Co	NJ	Health	MdEq	Surgical & Medical Instrument	Polen Thomas E Jr	NJ	DO	CB,CEO,P	M.d	7,238	167.25	43	65	110	D
8/14/26 16:36	8/13/26	BDX	Becton Dickinson & Co	NJ	Health	MdEq	Surgical & Medical Instrument	Polen Thomas E Jr	NJ	DO	CB,CEO,P	S.d	-768	185.00	-4	-4	110	D
8/14/26 16:35	8/13/26	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	Duato Joaquin	NJ	DO	CEO,CB	M.d	14,261	115.67	123	67	308	D
8/14/26 16:35	8/13/26	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	Duato Joaquin	NJ	DO	CEO,CB	S.d	-32,200	261.17	-123	-29	308	D
8/14/26 16:30	8/13/26	DNTH	Dianthus Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	Veness Adam M	NY	O	SVP,GC,S	M.d	273	18.17	15	New	15	D
8/14/26 16:29	8/13/26	AMRX	Amneal Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Kiely John	NJ	D		S	-882	17.64	-50	-20	200	D
8/14/26 16:18	8/12/26	MEDP	Medpace Holdings, Inc.	DE	Health	Biolab	Commercial Physical & Biologi	Troendle August J.	OH	DOT	P,CEO	S.m	-7,112	601.49	-12	0	5,337	D
8/14/26 16:12	8/12/26	TWST	Twist Bioscience Corp	DE	Health	BioPrd	Biological Products, (No Diag	Blake Katryn	CA	D		S	-275	122.88	-2	-12	17	D
8/14/26 16:05	8/12/26	VCEL	Vericel Corp	MI	Health	BioPrd	Biological Products, (No Diag	McLaughlin Kevin F	MA	D		M.d	91	13.05	7	62	18	D
8/14/26 16:05	8/12/26	VCEL	Vericel Corp	MI	Health	BioPrd	Biological Products, (No Diag	McLaughlin Kevin F	MA	D		S.d	-312	44.53	-7	-28	18	D
8/14/26 16:05	8/12/26	SLGL	Sol-Gel Technologies Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T		P	68	71.50	1	0	510	I
8/14/26 16:05	8/12/26	TWST	Twist Bioscience Corp	DE	Health	BioPrd	Biological Products, (No Diag	Leproust Emily M.	CA	DO	CEO	M.d	532	26.66	20	2	819	D
8/14/26 16:05	8/12/26	TWST	Twist Bioscience Corp	DE	Health	BioPrd	Biological Products, (No Diag	Leproust Emily M.	CA	DO	CEO	S.d	-2,496	125.08	-20	-2	819	D
8/14/26 16:01	8/6/26	AHCO	Adapthealth Corp.	DE	Health	Health	Home Health Care Services	Wolf Dale B	PA	D		P.a	126	6.30	20	13	177	D
8/14/26 16:01	8/12/26	INCY	Incyte Corp	DE	Health	Biolab	Commercial Physical & Biologi	Cagnoni Pablo J	DE	O	P,Global	S	-1,297	120.04	-11	-5	194	D
8/14/26 14:37	8/13/26	CBLL	Ceribell, Inc.	DE	Health	ElcMd	Electromedical & Electrothera	Taylor Joseph Michael	CA	D		S	-306	23.40	-13	-21	48	D
8/14/26 12:29	8/12/26	PFSA	Profusa, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Hrt Financial LP	NY	T		P	5	0.9640	6	8	74	D
8/14/26 12:29	8/13/26	PFSA	Profusa, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Hrt Financial LP	NY	T		S	-38	0.8880	-42	-36	74	D
8/14/26 12:04	8/14/26	ABCL	Abcellera Biologics Inc.	A1	Health	Drug	Pharmaceutical Preparations	Booth Andrew		O	CFO	P	384	10.32	37	6	614	D
8/14/26 11:50	8/12/26	ABCL	Abcellera Biologics Inc.	A1	Health	Drug	Pharmaceutical Preparations	Hayden Michael R		D		P	481	10.37	46	3	1,438	I
8/14/26 06:10	8/12/26	BLTE	Belite Bio, Inc	E9	Health	Drug	Pharmaceutical Preparations	Chuang Hao-Yuan	CA	DO	CFO	S	-66	180.35	0	0	93	D
8/14/26 06:10	8/12/26	BLTE	Belite Bio, Inc	E9	Health	Drug	Pharmaceutical Preparations	Lin Yu-Hsin	CA	DO	CEO	S	-66	180.35	0	0	171	D
8/13/26 21:52	8/5/26	ATTO	Attovia Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Walsh Colin	NY	D		P.dm	10,285	17.58	585	24	3,021	I
8/13/26 21:52	8/5/26	ATTO	Attovia Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Walsh Colin	NY	D		S.d	-2,252	21.28	-106	-3	3,021	I
8/13/26 21:00	8/11/26	WVE	Wave Life Sciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Wagner Heidi L	MA	D		M.d	42	5.97	7	18	45	D
8/13/26 21:00	8/11/26	WVE	Wave Life Sciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Wagner Heidi L	MA	D		S.d	-42	6.01	-7	-13	45	D
8/13/26 21:00	8/12/26	WVE	Wave Life Sciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rawcliffe Adrian	MA	D		S	-67	5.29	-13	-100	0	D
8/13/26 21:00	8/11/26	WVE	Wave Life Sciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Takanashi Ken		D		S	-23	6.01	-4	0	9,626	D
8/13/26 21:00	8/11/26	WVE	Wave Life Sciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tan Aik Na	MA	D		S	-3	6.01	0	-2	25	D
8/13/26 20:54	8/11/26	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Lee Chan Henry		O	SVP,GC	M.d	510	191.37	3	1	325	D
8/13/26 20:54	8/11/26	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Lee Chan Henry		O	SVP,GC	S.d	-960	360.00	-3	-1	325	D
8/13/26 20:18	8/13/26	CVRX	Cvrx, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Binkowski Brent	MN	O	COO	P	76	2.91	26	87	57	D
8/13/26 20:06	8/11/26	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Burnett Patrick	CA	O	See Rema	M.dm	55	3.64	15	14	119	D
8/13/26 20:06	8/11/26	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Burnett Patrick	CA	O	See Rema	S.dm	-395	26.33	-15	-11	119	D
8/13/26 19:57	8/11/26	GKOS	Glaukos Corp	DE	Health	MdEq	Surgical & Medical Instrument	Gilliam Joseph E	CA	O	P,COO	M.d	3,176	52.94	60	477	73	D
8/13/26 19:57	8/11/26	GKOS	Glaukos Corp	DE	Health	MdEq	Surgical & Medical Instrument	Gilliam Joseph E	CA	O	P,COO	S.d	-10,785	179.74	-60	-45	73	D
8/13/26 19:21	8/12/26	GH	Guardant Health, Inc.	DE	Health	Health	Medical Laboratories	Monroe Terilyn J.	CA	O	Chief Pe	M.d	1,051	22.70	46		23	D
8/13/26 19:21	8/12/26	GH	Guardant Health, Inc.	DE	Health	Health	Medical Laboratories	Monroe Terilyn J.	CA	O	Chief Pe	S.d	-7,645	165.12	-46	-67	23	D
8/13/26 19:05	8/11/26	AMGN	Amgen Inc	DE	Health	BioPrd	Biological Products, (No Diag	Khosla Rachna	CA	O	SVP,Busi	S.dm	-1,346	414.05	-3	-34	6	D
8/13/26 19:05	8/13/26	AMGN	Amgen Inc	DE	Health	BioPrd	Biological Products, (No Diag	Khosla Rachna	CA	O	SVP,Busi	M.d	204	162.60	1	24	6	D
8/13/26 19:00	8/11/26	SEPN	Septerna, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bhatt Elizabeth	CA	O	P,COO	M.d	145	5.79	25	17	174	D
8/13/26 19:00	8/11/26	SEPN	Septerna, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bhatt Elizabeth	CA	O	P,COO	S.d	-1,100	44.00	-25	-13	174	D
8/13/26 18:56	8/13/26	ICUI	Icu Medical Inc/De	DE	Health	MdEq	Surgical & Medical Instrument	Woolson Daniel	CA	O	VP,GM-In	S	-982	181.33	-5	-24	17	D
8/13/26 17:43	8/13/26	BCDA	Biocardia, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Altman Peter	CA	DO	P,CEO	P	2	0.9200	2	1	376	D
8/13/26 17:33	8/10/26	SRTA	Strata Critical Medical, Inc.	DE	Health	Health	Health Services	Love Reginald	NY	D		S	-29	5.75	-5	-3	146	D
8/13/26 17:22	8/12/26	BDSX	Biodesix Inc	DE	Health	Health	Medical Laboratories	Schuler Jack W	IL	TH	Emeritus	P	367	24.47	15	1	2,356	I
8/13/26 17:14	8/11/26	ABT	Abbott Laboratories	IL	Health	Drug	Pharmaceutical Preparations	Morrone Louis H.	IL	O	EVP	S	-643	109.83	-6	-8	71	M
8/13/26 17:09	8/12/26	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	M.d	1,286	135.42	10	1	669	I
8/13/26 17:09	8/12/26	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	S.d	-4,893	515.03	-10	-1	669	I
8/13/26 17:04	8/11/26	KRRO	Korro Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Formela Jean Francois	MA	D		S	-30	13.96	-2	-1	146	I
8/13/26 17:02	8/13/26	MRK	Merck & Co., Inc.	NJ	Health	Drug	Pharmaceutical Preparations	Guindo Chirfi	NJ	O	EVP,Acce	S	-1,350	135.00	-10	-21	37	D
8/13/26 17:02	8/11/26	LFST	Lifestance Health Group, Inc.	DE	Health	Health	Health Services	Burdick Kenneth A	AZ	D		S	-5,755	11.51	-500	-14	3,017	D
8/13/26 17:01	8/11/26	DNLI	Denali Therapeutics Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Schuth Alexander O.	CA	O	COFO,Sec	S	-72	25.07	-3	0	806	D
8/13/26 16:37	8/11/26	CRL	Charles River Laboratories International, Inc.		Health	Biolab	Commercial Physical & Biologi	Girshick Birgit	MA	DO	CEO	M.d	1,168	179.66	7	9	80	D
8/13/26 16:37	8/11/26	CRL	Charles River Laboratories International, Inc.		Health	Biolab	Commercial Physical & Biologi	Girshick Birgit	MA	DO	CEO	S.d	-1,819	279.90	-7	-8	80	D
8/13/26 16:34	8/11/26	CRL	Charles River Laboratories International, Inc.		Health	Biolab	Commercial Physical & Biologi	Parisotto Shannon M	MA	O	CEVP,Dis	M.d	667	179.66	4	9	43	D
8/13/26 16:34	8/11/26	CRL	Charles River Laboratories International, Inc.		Health	Biolab	Commercial Physical & Biologi	Parisotto Shannon M	MA	O	CEVP,Dis	S.d	-1,039	279.66	-4	-8	43	D
8/13/26 16:33	8/11/26	XENE	Xenon Pharmaceuticals Inc.	A1	Health	Drug	Pharmaceutical Preparations	Gannon Steven		D		S	-641	64.06	-10	-84	2	D
8/13/26 16:32	8/13/26	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Cook Meredith	NJ	O	SVP,GC,S	S	-38	75.48	-1	-1	74	D
8/13/26 16:28	8/12/26	ELAN	Elanco Animal Health Inc		Health	Drug	Pharmaceutical Preparations	Harrington Michael J	IN	D		P	109	21.82	5	4	131	D
8/13/26 16:26	8/12/26	CVRX	Cvrx, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Binkowski Brent	MN	O	COO	S	-3	2.55	-1	-4	30	D
8/13/26 16:22	8/12/26	AMRX	Amneal Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Shah Nikita	NJ	O	EVP	S	-2,564	17.51	-146	-37	253	D
8/13/26 16:21	8/11/26	AMRX	Amneal Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Daly Jason B.	NJ	O	EVP,GC	S.m	-3,771	17.41	-217	-86	35	D
8/13/26 16:21	8/11/26	AMRX	Amneal Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Buchi J Kevin	NJ	D		M	2,896	17.18	169	999%	169	I
8/13/26 16:15	8/12/26	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Lis William	MA	D		S	-213	25.00	-9	-17	42	D
8/13/26 16:15	8/11/26	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Stevens Christopher James	NJ	O	COO	S	-128	3.50	-37	-7	506	D
8/13/26 16:15	8/11/26	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chaudhuri Sarbani	NJ	O	See Rema	S	-16	3.50	-5	-2	263	D
8/13/26 16:15	8/11/26	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Chen Yajing	MA	O	CFO	S	-15	25.00	-1	-2	35	D
8/13/26 16:13	8/12/26	XFOR	X4 Pharmaceuticals, Inc	DE	Health	BioPrd	Biological Products, (No Diag	Volpone John	MA	O	P	S	-109	4.44	-25	-8	265	D
8/13/26 16:12	8/11/26	MEDP	Medpace Holdings, Inc.	DE	Health	Biolab	Commercial Physical & Biologi	McCarthy Cornelius P. III	OH	D		S	-690	605.37	-1	-8	12	D
8/13/26 16:11	8/12/26	MRK	Merck & Co., Inc.	NJ	Health	Drug	Pharmaceutical Preparations	Zachary Jennifer	NJ	O	EVP,GC	M.d	6,030	109.78	55		46	D
8/13/26 16:11	8/12/26	MRK	Merck & Co., Inc.	NJ	Health	Drug	Pharmaceutical Preparations	Zachary Jennifer	NJ	O	EVP,GC	S.d	-10,718	133.46	-80	-64	46	D
8/13/26 16:10	8/12/26	XFOR	X4 Pharmaceuticals, Inc	DE	Health	BioPrd	Biological Products, (No Diag	Craig Adam R	MA	DO	Exec CB	S	-211	4.44	-47	-13	329	D
8/13/26 16:05	8/13/26	ALT	Altimmune, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Durso Jerome Benedict	MD	DO	P,CEO	P	44	2.95	15	32	63	D
8/13/26 16:04	8/11/26	LIVN	Livanova Plc	X0	Health	ElcMd	Electromedical & Electrothera	Tezel Ahmet		O	Chief In	M.d	669	52.68	13		6	D
8/13/26 16:04	8/11/26	LIVN	Livanova Plc	X0	Health	ElcMd	Electromedical & Electrothera	Tezel Ahmet		O	Chief In	S.d	-208	77.74	-3	-31	6	D
8/13/26 16:04	8/12/26	DXCM	Dexcom Inc	DE	Health	MdEq	Surgical & Medical Instrument	Heller Bridgette P	CA	D		S	-89	88.29	-1	-3	30	D
8/13/26 10:50	8/12/26	EMBC	Embecta Corp.	DE	Health	MdEq	Surgical & Medical Instrument	Kurdikar Devdatt	NJ	DO	P,CEO	P	141	4.70	30	4	805	D
8/13/26 10:48	8/12/26	EMBC	Embecta Corp.	DE	Health	MdEq	Surgical & Medical Instrument	Elguicze Jacob	NJ	O	SVP,CFO	P	93	4.67	20	7	309	D
8/13/26 10:47	8/12/26	EMBC	Embecta Corp.	DE	Health	MdEq	Surgical & Medical Instrument	Mann Jeffrey Z	NJ	O	P,Pharm	P	100	4.99	20	8	263	D
8/13/26 10:45	8/12/26	EMBC	Embecta Corp.	DE	Health	MdEq	Surgical & Medical Instrument	Hombach Robert J.	NJ	D		P	224	4.97	45	70	110	D
8/13/26 09:54	8/6/26	KRRO	Korro Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lynx1 Capital Management LP		T		P.m	79	11.79	7	0	1,545	I
8/12/26 21:54	8/10/26	TAK	Takeda Pharmaceutical Co Ltd		Health	Drug	Pharmaceutical Preparations	Farajallah Awny Samaan Botros	MA	O	Chief Me	S	-240	17.10	-14	-11	116	D
8/12/26 21:53	8/10/26	TAK	Takeda Pharmaceutical Co Ltd		Health	Drug	Pharmaceutical Preparations	Ibrahim Ramy Riad Ahmed	MA	O	P,PDT BU	S	-124	17.10	-7	-7	103	D
8/12/26 21:53	8/10/26	TAK	Takeda Pharmaceutical Co Ltd		Health	Drug	Pharmaceutical Preparations	Pacheco Rhonda Janice	MA	O	P,U.S. B	S	-289	17.10	-17	-8	183	D
8/12/26 21:51	8/10/26	TAK	Takeda Pharmaceutical Co Ltd		Health	Drug	Pharmaceutical Preparations	Duprey Lauren Rusckowski	MA	O	Chief Tr	S	-814	17.10	-48	-17	226	D
8/12/26 21:50	8/10/26	TAK	Takeda Pharmaceutical Co Ltd		Health	Drug	Pharmaceutical Preparations	Plump Andrew Stewart	MA	DO	P,R,D	S	-2,828	17.10	-165	-14	1,048	D
8/12/26 21:46	8/10/26	TAK	Takeda Pharmaceutical Co Ltd		Health	Drug	Pharmaceutical Preparations	Pignagnoli Agosti Marcello	MA	O	Head,Str	S	-393	17.10	-23	-11	177	D
8/12/26 21:45	8/10/26	TAK	Takeda Pharmaceutical Co Ltd		Health	Drug	Pharmaceutical Preparations	Bitetti Teresa Marie	MA	O	P,OBU	S	-855	17.10	-50	-17	252	D
8/12/26 21:43	8/3/26	HEPA	Hepion Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Stetz Gary S. II	NJ	D		P.d	25	0.0500	500	New	500	D
8/12/26 21:42	8/10/26	TAK	Takeda Pharmaceutical Co Ltd		Health	Drug	Pharmaceutical Preparations	Shannon Elaine Mary	MA	O	P,Global	S	-68	17.10	-4	-6	63	D
8/12/26 21:41	8/3/26	HEPA	Hepion Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Stetz Gary S.	NJ	DO	Interim	P.d	100	0.0500	2,000	160	3,250	D
8/12/26 21:39	8/10/26	TAK	Takeda Pharmaceutical Co Ltd		Health	Drug	Pharmaceutical Preparations	Ricci Gabriele	MA	O	Chief Da	S	-429	17.10	-25	-13	172	D
8/12/26 21:39	8/3/26	HEPA	Hepion Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Purcell Michael J.	NJ	D		P.d	100	0.0500	2,000	160	3,250	D
8/12/26 21:36	8/3/26	HEPA	Hepion Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Appajosyula Sireesh	NJ	DO	COO	P.d	100	0.0500	2,000	160	3,250	D
8/12/26 21:34	8/3/26	HEPA	Hepion Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lopriore Vincent S	NJ	DO	Exec CB	P.d	500	0.0500	10,000	49	30,500	I
8/12/26 21:28	8/10/26	TAK	Takeda Pharmaceutical Co Ltd		Health	Drug	Pharmaceutical Preparations	Greenway Nicola Deidre Petal	MA	O	CHRO	S	-116	17.10	-7	-11	53	D
8/12/26 21:27	8/10/26	TAK	Takeda Pharmaceutical Co Ltd		Health	Drug	Pharmaceutical Preparations	Kim Julie So-Young	MA	DO	P,CEO	S	-1,523	17.10	-89	-19	391	D
8/12/26 21:25	8/10/26	TAK	Takeda Pharmaceutical Co Ltd		Health	Drug	Pharmaceutical Preparations	Platford Giles Richard	MA	O	P,IBU	S	-532	17.10	-31	-9	316	D
8/12/26 21:23	8/10/26	TAK	Takeda Pharmaceutical Co Ltd		Health	Drug	Pharmaceutical Preparations	Furney Natalie Anne Marie	MA	O	Global G	S	-528	17.10	-31	-13	204	D
8/12/26 19:41	8/11/26	SGMT	Sagimet Biosciences Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kemble George	CA	D		M.d	129	6.36	20	48	62	D
8/12/26 19:41	8/11/26	SGMT	Sagimet Biosciences Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kemble George	CA	D		S.d	-201	9.95	-20	-25	62	D
8/12/26 19:34	8/10/26	EXEL	Exelixis, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Beckerle Mary C	CA	D		S	-527	53.66	-10	-38	16	D
8/12/26 19:33	8/10/26	ADPT	Adaptive Biotechnologies Corp	WA	Health	BioPrd	Biological Products, (No Diag	Bobulsky Susan	WA	O	Chief Co	S	-75	25.00	-3	-1	397	D
8/12/26 19:33	8/10/26	MLYS	Mineralys Therapeutics, Inc.		Health	Drug	Pharmaceutical Preparations	Rodman David Malcom	PA	O	Chief Me	M.d	35	16.00	2	4	51	D
8/12/26 19:33	8/10/26	MLYS	Mineralys Therapeutics, Inc.		Health	Drug	Pharmaceutical Preparations	Rodman David Malcom	PA	O	Chief Me	S.d	-59	27.09	-2	-4	51	D
8/12/26 19:06	8/10/26	BLCO	Bausch & Lomb Corp		Health	OthMd	Ophthalmic Goods	Munsch Frederick		O	SVP,Cont	S	-888	16.78	-53	-54	46	D
8/12/26 18:55	8/10/26	BLLN	Billiontoone, Inc.	DE	Health	Health	Medical Laboratories	Ten Bosch John Roderick	CA	O	SVP of L	S	-132	92.86	-1	-5	28	D
8/12/26 18:51	8/11/26	PTIX	Protagenic Therapeutics, Inc.New	DE	Health	Drug	Pharmaceutical Preparations	Armen Garo H	MA	DO	EXEC. CH	P	1	0.3200	2	7	34	D
8/12/26 18:51	8/10/26	BLLN	Billiontoone, Inc.	DE	Health	Health	Medical Laboratories	Tsao David	CA	DO	CTO	M.d	28	2.80	10		1	D
8/12/26 18:51	8/10/26	BLLN	Billiontoone, Inc.	DE	Health	Health	Medical Laboratories	Tsao David	CA	DO	CTO	S.d	-929	92.86	-10	-91	1	D
8/12/26 18:43	8/10/26	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	Patel Dinesh V Ph D	CA	DO	P,CEO	M.dm	2,158	21.58	100	24	523	D
8/12/26 18:43	8/10/26	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	Patel Dinesh V Ph D	CA	DO	P,CEO	S.dm	-14,891	148.91	-100	-16	523	D
8/12/26 18:42	7/7/26	VERA	Vera Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fordyce Marshall	CA	DO	P,CEO	M.ad	134	2.90	46	24	235	D
8/12/26 18:42	7/7/26	VERA	Vera Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fordyce Marshall	CA	DO	P,CEO	S.ad	-1,956	42.30	-46	-16	235	D
8/12/26 18:41	6/23/26	VERA	Vera Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fordyce Marshall	CA	DO	P,CEO	M.ad	54	2.90	19	9	235	D
8/12/26 18:41	6/23/26	VERA	Vera Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fordyce Marshall	CA	DO	P,CEO	S.ad	-702	37.93	-19	-7	235	D
8/12/26 18:39	5/12/26	VERA	Vera Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fordyce Marshall	CA	DO	P,CEO	M.ad	54	2.90	19	9	235	D
8/12/26 18:39	5/12/26	VERA	Vera Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fordyce Marshall	CA	DO	P,CEO	S.ad	-680	36.74	-19	-7	235	D
8/12/26 18:14	8/11/26	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Prins Richard K	CA	D		S	-162	20.30	-8	-21	30	D
8/12/26 17:55	8/10/26	BDSX	Biodesix Inc	DE	Health	Health	Medical Laboratories	Schuler Jack W	IL	TH	Emeritus	P.m	666	24.13	28	1	2,341	I
8/12/26 17:53	8/10/26	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Oyler John		DO	CEO	S.m	-86,480	359.12	-241	-1	47,363	D
8/12/26 17:51	8/12/26	AORT	Artivion, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Holloway Jean F	GA	O	SVP,GC	S	-28	28.49	-1	-1	184	D
8/12/26 17:47	8/10/26	IMNM	Immunome Inc.	DE	Health	Drug	Pharmaceutical Preparations	Barchas Isaac	WA	D		S.m	-2,199	26.35	-83	-48	92	M
8/12/26 17:30	8/10/26	IOVA	Iovance Biotherapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Kirby Daniel Gordon	CA	O	Chief Co	M.d	0	0.00	10	7	155	D
8/12/26 17:27	8/11/26	BDX	Becton Dickinson & Co	NJ	Health	MdEq	Surgical & Medical Instrument	Goette Roland	NJ	O	EVP,P,EM	S	-441	180.84	-2	-13	17	D
8/12/26 17:14	8/11/26	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bjerkholt Eric	CA	O	CFO	S	-600	99.90	-6	-14	36	D
8/12/26 17:07	8/10/26	REPL	Replimune Group, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Patel Sushil	MA	DO	CEO	S	-510	12.97	-39	-5	708	D
8/12/26 17:07	8/10/26	LFST	Lifestance Health Group, Inc.	DE	Health	Health	Health Services	Paunovich Vukasin	AZ	O	CTO	S	-482	10.85	-44	-15	247	D
8/12/26 17:07	8/10/26	HTFL	Heartflow, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Farquhar John C.M.	CA	DO	CEO	S	-639	28.31	-23	-5	436	D
8/12/26 17:06	8/10/26	REPL	Replimune Group, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Hill Emily Luisa	MA	O	CFO	S	-148	12.97	-11	-5	225	D
8/12/26 17:05	8/10/26	REPL	Replimune Group, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Xynos Konstantinos	MA	O	Chief Me	S	-148	12.97	-11	-5	224	D
8/12/26 17:04	8/10/26	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Adsett Roger	NJ	O	COO	M.d	4,906	20.45	240		99	D
8/12/26 17:04	8/10/26	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Adsett Roger	NJ	O	COO	S.d	-31,965	133.27	-240	-71	99	D
8/12/26 17:04	8/10/26	REPL	Replimune Group, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Schwendenman Andrew	MA	O	Chief Ac	S	-99	12.97	-8	-7	99	D
8/12/26 17:03	8/11/26	BFLY	Butterfly Network, Inc.	DE	Health	OthMd	X-Ray Apparatus & Tubes & Rel	Caezza Nicholas	MA	O	Deputy G	S	-98	9.75	-10	-3	300	D
8/12/26 17:02	8/10/26	ICLR	Icon Plc		Health	Biolab	Commercial Physical & Biologi	Whitaker Anne Clem		D		M.d	0	0.00	2		1	D
8/12/26 17:02	8/11/26	ICLR	Icon Plc		Health	Biolab	Commercial Physical & Biologi	Whitaker Anne Clem		D		S.d	-138	164.29	-1	-49	1	D
8/12/26 17:02	8/10/26	LFST	Lifestance Health Group, Inc.	DE	Health	Health	Health Services	Tpg Gp A, LLC	TX	T		S	-144,891	10.62	-13,643	-12	98,101	I
8/12/26 17:01	8/10/26	ICLR	Icon Plc		Health	Biolab	Commercial Physical & Biologi	O'Neill Julie		D		M.d	0	0.00	2	97	4	D
8/12/26 17:01	8/11/26	ICLR	Icon Plc		Health	Biolab	Commercial Physical & Biologi	O'Neill Julie		D		S.d	-150	164.29	-1	-21	4	D
8/12/26 17:00	8/10/26	ICLR	Icon Plc		Health	Biolab	Commercial Physical & Biologi	Murray Ciaran		D		M.d	0	0.00	3	15	20	D
8/12/26 17:00	8/11/26	ICLR	Icon Plc		Health	Biolab	Commercial Physical & Biologi	Murray Ciaran		D		S.d	-440	164.29	-3	-12	20	D
8/12/26 17:00	8/10/26	ICLR	Icon Plc		Health	Biolab	Commercial Physical & Biologi	Murphy Ronan Martin		D		M.d	0	0.00	2	82	4	D
8/12/26 17:00	8/11/26	ICLR	Icon Plc		Health	Biolab	Commercial Physical & Biologi	Murphy Ronan Martin		D		S.d	-138	164.29	-1	-18	4	D
8/12/26 16:59	8/10/26	ICLR	Icon Plc		Health	Biolab	Commercial Physical & Biologi	McCague Eugene Pacelli		D		M.d	0	0.00	2	83	4	D
8/12/26 16:59	8/11/26	ICLR	Icon Plc		Health	Biolab	Commercial Physical & Biologi	McCague Eugene Pacelli		D		S.d	-138	164.29	-1	-18	4	D
8/12/26 16:59	8/10/26	LFST	Lifestance Health Group, Inc.	DE	Health	Health	Health Services	Miller Lisa K	AZ	O	COO	S	-520	10.85	-48	-15	281	D
8/12/26 16:50	8/12/26	OMDA	Omada Health, Inc.	DE	Health	Health	Health Services	Shao Wei-Li	CA	O	P	S	-222	25.02	-9	-3	307	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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