IONS - Ionis Pharmaceuticals Inc - Insider Stock Trading

Filing Date	T Date	Ticker	Sector	Ind	Industry	Owner	oSt	Rel	Title	#f	T	TVal	Price	Qty	oc	Own	H
3/5/26 18:14	3/3/26	IONS	Health	Drug	Pharmaceutical Preparations	Loscalzo Joseph	CA	D		2	M.dm	122	59.16	2	6	36	D
3/5/26 18:14	3/3/26	IONS	Health	Drug	Pharmaceutical Preparations	Loscalzo Joseph	CA	D		2	S.dm	-122	59.16	-2		36	D
3/5/26 18:14	3/3/26	IONS	Health	Drug	Pharmaceutical Preparations	Klein Joseph III	CA	D		2	M.d	2,348	62.90	37		11	D
3/5/26 18:14	3/3/26	IONS	Health	Drug	Pharmaceutical Preparations	Klein Joseph III	CA	D		2	S.d	-2,348	62.90	-37		11	D
3/5/26 18:14	3/3/26	IONS	Health	Drug	Pharmaceutical Preparations	Diaz Allene M.	CA	D		2	M.d	5,956	62.56	95		4	D
3/5/26 18:14	3/3/26	IONS	Health	Drug	Pharmaceutical Preparations	Diaz Allene M.	CA	D		2	S.d	-5,956	62.56	-95		4	D
3/5/26 18:14	3/3/26	IONS	Health	Drug	Pharmaceutical Preparations	Devers Shannon L.	CA	O	EVP,Chie	7	M.d	9,304	58.77	158		27	D
3/5/26 18:14	3/3/26	IONS	Health	Drug	Pharmaceutical Preparations	Devers Shannon L.	CA	O	EVP,Chie	7	S.d	-9,304	58.77	-158		27	D
3/5/26 18:13	3/3/26	IONS	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	EVP,Chie	7	M.d	21,956	65.29	336		100	D
3/5/26 18:13	3/3/26	IONS	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	EVP,Chie	7	S.d	-21,956	65.29	-336		100	D
3/5/26 18:13	3/3/26	IONS	Health	Drug	Pharmaceutical Preparations	Baroldi Joseph	CA	O	EVP,Chie	5	S.dm	-1,676	39.87	-42		50	M
3/5/26 18:13	3/3/26	IONS	Health	Drug	Pharmaceutical Preparations	Baroldi Joseph	CA	O	EVP,Chie	5	M.dm	1,676	39.87	42	516	50	M
2/13/26 19:40	2/13/26	IONS	Health	Drug	Pharmaceutical Preparations	Swayze Eric	CA	O	EVP Rese	6	S.d	-5,825	58.16	-100		48	D
2/13/26 19:40	2/11/26	IONS	Health	Drug	Pharmaceutical Preparations	Parshall B Lynne	CA	D		1	S	-414	82.72	-5		56	D
2/10/26 17:04	2/6/26	IONS	Health	Drug	Pharmaceutical Preparations	Monia Brett P	CA	DO	CEO	4	S.d	-11,028	48.89	-226		284	D
2/2/26 20:52	1/30/26	IONS	Health	Drug	Pharmaceutical Preparations	Schneider Eugene	CA	O	EVP,Chf	3	S.d	-1,219	32.79	-37		70	D
2/2/26 20:51	1/30/26	IONS	Health	Drug	Pharmaceutical Preparations	O'Neil Patrick R.	CA	O	EVP CLO,	3	S.d	-1,213	32.93	-37		72	D
2/2/26 20:51	1/30/26	IONS	Health	Diagn	In Vitro & In Vivo Diagnostic	Hougen Elizabeth L	CA	O	EVP,Fina	3	S.d	-1,554	31.94	-49		133	D
2/2/26 20:51	1/30/26	IONS	Health	Drug	Pharmaceutical Preparations	Birchler Brian	CA	O	EVP,Corp	3	S.d	-1,150	33.09	-35		66	D
1/20/26 20:21	1/15/26	IONS	Health	Drug	Pharmaceutical Preparations	Yang Michael J.	CA	D		1	M.d	0	0.00	2	32	8	D
1/20/26 20:18	1/15/26	IONS	Health	Drug	Pharmaceutical Preparations	Kordasiewicz Holly B.	CA	O	EVP,Chie	2	M.d	313	20.53	15		15	D
1/20/26 20:18	1/16/26	IONS	Health	Drug	Pharmaceutical Preparations	Kordasiewicz Holly B.	CA	O	EVP,Chie	2	S.d	-313	20.53	-15		15	D
1/20/26 20:18	1/15/26	IONS	Health	Drug	Pharmaceutical Preparations	Jenne Kyle	CA	O	EVP,Chf	2	M.d	138	15.67	9	117	16	D
1/20/26 20:18	1/16/26	IONS	Health	Drug	Pharmaceutical Preparations	Jenne Kyle	CA	O	EVP,Chf	2	S.d	-138	15.67	-9		16	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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