IONS - Ionis Pharmaceuticals Inc - Insider Stock Trading

Filing Date	T Date	Ticker	Sector	Ind	Industry	Owner	oSt	Rel	Title	#f	T	TVal	Price	Qty	oc	Own	H
12/3/25 19:01	12/1/25	IONS	Health	Drug	Pharmaceutical Preparations	Wender Joseph H	CA	D		4	S.dm	-5,827	65.61	-89		92	I
11/28/25 17:51	11/25/25	IONS	Health	Drug	Pharmaceutical Preparations	Klein Joseph III	CA	D		2	M.d	960	40.00	24		16	I
11/28/25 17:51	11/25/25	IONS	Health	Drug	Pharmaceutical Preparations	Klein Joseph III	CA	D		2	S.d	-960	40.00	-24		16	I
11/28/25 17:51	11/25/25	IONS	Health	Drug	Pharmaceutical Preparations	Devers Shannon L.	CA	O	EVP,Chie	4	M.dm	3,081	62.08	50		17	D
11/28/25 17:51	11/25/25	IONS	Health	Drug	Pharmaceutical Preparations	Devers Shannon L.	CA	O	EVP,Chie	4	S.dm	-3,081	62.08	-50		17	D
11/20/25 17:12	11/19/25	IONS	Health	Drug	Pharmaceutical Preparations	Herman Joan E	CA	D		2	M.d	5,699	64.76	88		46	D
11/20/25 17:12	11/19/25	IONS	Health	Drug	Pharmaceutical Preparations	Herman Joan E	CA	D		2	S.d	-5,699	64.76	-88		46	D
11/7/25 17:13	11/6/25	IONS	Health	Drug	Pharmaceutical Preparations	Birchler Brian	CA	O	EVP,Corp	3	S.dm	-3,618	64.85	-56		57	D
11/7/25 17:12	11/5/25	IONS	Health	Drug	Pharmaceutical Preparations	Geary Richard S	CA	O	EVP,Chie	8	M.dm	22,785	65.05	350		80	D
11/7/25 17:12	11/5/25	IONS	Health	Drug	Pharmaceutical Preparations	Geary Richard S	CA	O	EVP,Chie	8	S.dm	-22,785	65.05	-350		80	D
11/3/25 20:14	10/31/25	IONS	Health	Drug	Pharmaceutical Preparations	Loscalzo Joseph	CA	D		2	M.d	2,037	63.66	32	739	36	D
11/3/25 20:14	10/31/25	IONS	Health	Drug	Pharmaceutical Preparations	Loscalzo Joseph	CA	D		2	S.d	-2,037	63.66	-32		36	D
10/16/25 20:16	10/15/25	IONS	Health	Drug	Pharmaceutical Preparations	Swayze Eric	CA	O	EVP Rese	5	M.dm	3,728	60.87	61		37	I
10/16/25 20:16	10/16/25	IONS	Health	Drug	Pharmaceutical Preparations	Swayze Eric	CA	O	EVP Rese	5	S.dm	-3,728	60.87	-61		37	I
10/16/25 20:16	10/15/25	IONS	Health	Drug	Pharmaceutical Preparations	Parshall B Lynne	CA	D		1	S	-359	71.74	-5		61	D
10/8/25 18:37	10/6/25	IONS	Health	Drug	Pharmaceutical Preparations	O'Neil Patrick R.	CA	O	EVP CLO,	10	M.dm	15,575	62.56	249		57	D
10/8/25 18:37	10/6/25	IONS	Health	Drug	Pharmaceutical Preparations	O'Neil Patrick R.	CA	O	EVP CLO,	10	S.dm	-15,575	62.56	-249		57	D
10/8/25 18:36	10/6/25	IONS	Health	Drug	Pharmaceutical Preparations	Monia Brett P	CA	DO	CEO	1	S	-30	69.26	0	0	180	D
10/8/25 18:36	10/6/25	IONS	Health	Drug	Pharmaceutical Preparations	Baroldi Joseph	CA	O	EVP,Chie	7	S.d	-2,756	49.20	-56		35	D
10/1/25 16:55	9/30/25	IONS	Health	Diagn	In Vitro & In Vivo Diagnostic	Hougen Elizabeth L	CA	O	EVP,Fina	2	M.d	5,927	59.51	100	914	111	D
10/1/25 16:55	9/30/25	IONS	Health	Diagn	In Vitro & In Vivo Diagnostic	Hougen Elizabeth L	CA	O	EVP,Fina	2	S.d	-5,927	59.51	-100		111	D
9/9/25 18:30	9/5/25	IONS	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	EVP,Chie	1	S	-358	59.60	-6		83	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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