IONS - Ionis Pharmaceuticals Inc - Insider Stock Trading

Filing Date	T Date	Ticker	Sector	Ind	Industry	Owner	oSt	Rel	Title	#f	T	TVal	Price	Qty	oc	Own	H
10/16/25 20:16	10/15/25	IONS	Health	Drug	Pharmaceutical Preparations	Swayze Eric	CA	O	EVP Rese	6	M.dm	4,281	59.14	72		37	I
10/16/25 20:16	10/16/25	IONS	Health	Drug	Pharmaceutical Preparations	Swayze Eric	CA	O	EVP Rese	6	S.dm	-4,281	59.14	-72		37	I
10/16/25 20:16	10/15/25	IONS	Health	Drug	Pharmaceutical Preparations	Parshall B Lynne	CA	D		3	S	-1,587	52.89	-30		86	D
10/16/25 20:16	10/15/25	IONS	Health	Drug	Pharmaceutical Preparations	Devers Shannon L.	CA	O	EVP,Chie	4	M.dm	1,129	50.38	22		17	D
10/16/25 20:16	10/15/25	IONS	Health	Drug	Pharmaceutical Preparations	Devers Shannon L.	CA	O	EVP,Chie	4	S.dm	-1,129	50.38	-22		17	D
10/16/25 20:15	10/14/25	IONS	Health	Drug	Pharmaceutical Preparations	Birchler Brian	CA	O	EVP,Corp	2	M.dm	3,009	62.95	48	530	57	D
10/16/25 20:15	10/14/25	IONS	Health	Drug	Pharmaceutical Preparations	Birchler Brian	CA	O	EVP,Corp	2	S.dm	-3,009	62.95	-48		57	D
10/8/25 18:37	10/6/25	IONS	Health	Drug	Pharmaceutical Preparations	O'Neil Patrick R.	CA	O	EVP CLO,	12	M.dm	25,027	58.37	429		57	D
10/8/25 18:37	10/6/25	IONS	Health	Drug	Pharmaceutical Preparations	O'Neil Patrick R.	CA	O	EVP CLO,	12	S.dm	-25,027	58.37	-429		57	D
10/8/25 18:36	10/6/25	IONS	Health	Drug	Pharmaceutical Preparations	Monia Brett P	CA	DO	CEO	5	S.d	-21,546	52.18	-413		180	D
10/8/25 18:36	10/6/25	IONS	Health	Drug	Pharmaceutical Preparations	Baroldi Joseph	CA	O	EVP,Chie	9	S.d	-5,745	47.24	-122		35	D
10/2/25 19:36	10/1/25	IONS	Health	Drug	Pharmaceutical Preparations	Wender Joseph H	CA	D		3	S.m	-4,325	59.41	-73		109	I
10/1/25 16:55	9/30/25	IONS	Health	Drug	Pharmaceutical Preparations	Geary Richard S	CA	O	EVP,Chie	4	M.d	7,823	57.61	136		89	D
10/1/25 16:55	9/30/25	IONS	Health	Drug	Pharmaceutical Preparations	Geary Richard S	CA	O	EVP,Chie	4	S.d	-7,823	57.61	-136		89	D
10/1/25 16:55	9/30/25	IONS	Health	Diagn	In Vitro & In Vivo Diagnostic	Hougen Elizabeth L	CA	O	EVP,Fina	2	M.d	5,927	59.51	100	914	111	D
10/1/25 16:55	9/30/25	IONS	Health	Diagn	In Vitro & In Vivo Diagnostic	Hougen Elizabeth L	CA	O	EVP,Fina	2	S.d	-5,927	59.51	-100		111	D
9/9/25 18:30	9/5/25	IONS	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	EVP,Chie	5	S.dm	-6,734	54.04	-125		93	D
9/4/25 20:38	9/3/25	IONS	Health	Drug	Pharmaceutical Preparations	Klein Joseph III	CA	D		4	M.d	3,360	30.00	112		16	I
9/4/25 20:38	9/3/25	IONS	Health	Drug	Pharmaceutical Preparations	Klein Joseph III	CA	D		4	S.d	-3,360	30.00	-112		16	I
9/4/25 20:28	9/3/25	IONS	Health	Drug	Pharmaceutical Preparations	Loscalzo Joseph	CA	D		2	M.d	1,353	42.28	32	739	36	D
9/4/25 20:28	9/3/25	IONS	Health	Drug	Pharmaceutical Preparations	Loscalzo Joseph	CA	D		2	S.d	-1,353	42.28	-32		36	D
9/4/25 20:28	9/3/25	IONS	Health	Drug	Pharmaceutical Preparations	Schneider Eugene	CA	O	EVP,Chf	3	M.d	2,661	54.46	49	999%	52	D
9/4/25 20:28	9/3/25	IONS	Health	Drug	Pharmaceutical Preparations	Schneider Eugene	CA	O	EVP,Chf	3	S.d	-2,661	54.46	-49		52	D
8/26/25 17:23	8/22/25	IONS	Health	Drug	Pharmaceutical Preparations	Diaz Allene M.	CA	D		1	S	-61	42.53	-1		18	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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