12/3/25 21:52 | 12/1/25 | SYRE | Spyre Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Turtle Cameron | MA | DO | CEO | S | -435 | 29.02 | 0 | -15 | -2 | 687 | D | | | | | | | | | | | | | | |
12/3/25 21:19 | 12/2/25 | CORT | Corcept Therapeutics Inc | DE | Health | Drug | Pharmaceutical Preparations | Guyer William | CA | O | Chief De | S.d | -1,602 | 80.08 | 0 | -20 | -94 | 1 | M | | | | | | | | | | | | | | |
12/3/25 20:53 | 12/1/25 | CORT | Corcept Therapeutics Inc | DE | Health | Drug | Pharmaceutical Preparations | Maduck Sean | CA | O | See Rema | S.d | -1,590 | 79.52 | 0 | -20 | -15 | 118 | D | | | | | | | | | | | | | | |
12/3/25 20:36 | 12/1/25 | CORT | Corcept Therapeutics Inc | DE | Health | Drug | Pharmaceutical Preparations | Lyon Joseph Douglas | CA | O | See Rema | S.d | -398 | 79.53 | 0 | -5 | -32 | 11 | D | | | | | | | | | | | | | | |
12/3/25 20:23 | 12/2/25 | STOK | Stoke Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Ticho Barry | MA | O | Chief Me | S.dm | -121 | 30.22 | 0 | -4 | -21 | 15 | D | | | | | | | | | | | | | | |
12/3/25 20:22 | 12/2/25 | STOK | Stoke Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kaye Edward M. Md | MA | D | | S.dm | -65 | 30.22 | 0 | -2 | -4 | 51 | D | | | | | | | | | | | | | | |
12/3/25 20:20 | 11/28/25 | XENE | Xenon Pharmaceuticals Inc. | A1 | Health | Drug | Pharmaceutical Preparations | Mortimer Ian | A1 | DO | P,CEO | S | -4 | 45.01 | 0 | 0 | 0 | 46 | D | | | | | | | | | | | | | | |
12/3/25 20:20 | 12/2/25 | STOK | Stoke Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Allan Jonathan | MA | O | GC,Corp | S.dm | -138 | 30.22 | 0 | -5 | -19 | 20 | D | | | | | | | | | | | | | | |
12/3/25 20:14 | 12/1/25 | CORT | Corcept Therapeutics Inc | DE | Health | Drug | Pharmaceutical Preparations | Belanoff Joseph K | CA | DO | CEO | S | -3,191 | 79.77 | 0 | -40 | -1 | 2,701 | I | | | | | | | | | | | | | | |
12/3/25 20:11 | 12/1/25 | FOLD | Amicus Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Campbell Bradley L | NJ | DO | P,CEO | S.d | -146 | 10.01 | 0 | -15 | -1 | 1,137 | D | | | | | | | | | | | | | | |
12/3/25 20:08 | 11/25/25 | CORT | Corcept Therapeutics Inc | DE | Health | Drug | Pharmaceutical Preparations | Guyer William | CA | O | Chief De | S.a | -364 | 80.90 | 0 | -5 | -85 | 1 | M | | | | | | | | | | | | | | |
12/3/25 20:00 | 12/1/25 | JANX | Janux Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Meyer Andrew Hollman | CA | O | Chief Bu | S.d | -110 | 32.98 | 0 | -3 | -4 | 85 | D | | | | | | | | | | | | | | |
12/3/25 19:01 | 12/1/25 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Wender Joseph H | CA | D | | S | -2,263 | 80.82 | 0 | -28 | -35 | 52 | I | | | | | | | | | | | | | | |
12/3/25 17:59 | 12/2/25 | MDGL | Madrigal Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Dier Mardi | PA | O | EVP,CFO | S.d | -2,413 | 578.34 | 0 | -4 | -29 | 10 | D | | | | | | | | | | | | | | |
12/3/25 17:24 | 12/1/25 | ARQT | Arcutis Biotherapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Matsuda Masaru | CA | O | See Rema | S | -50 | 30.23 | 0 | -2 | -1 | 151 | D | | | | | | | | | | | | | | |
12/3/25 17:23 | 12/1/25 | ARQT | Arcutis Biotherapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Welgus Howard G. | CA | D | | S | -302 | 30.21 | 0 | -10 | -11 | 80 | D | | | | | | | | | | | | | | |
12/3/25 17:11 | 12/1/25 | RPRX | Royalty Pharma Plc | X0 | Health | Drug | Pharmaceutical Preparations | Coyne Terrance P. | NY | O | EVP,CFO | S | -2,774 | 39.87 | 0 | -70 | -9 | 690 | I | | | | | | | | | | | | | | |
12/3/25 17:10 | 12/1/25 | RPRX | Royalty Pharma Plc | X0 | Health | Drug | Pharmaceutical Preparations | Urist Marshall | NY | O | EVP,Rese | S | -1,659 | 39.92 | 0 | -42 | -15 | 228 | M | | | | | | | | | | | | | | |
12/3/25 17:09 | 12/2/25 | ENTA | Enanta Pharmaceuticals Inc | | Health | Drug | Pharmaceutical Preparations | Capps Kathleen S. | MA | O | See Rema | S | -3 | 13.96 | 0 | 0 | -2 | 9 | D | | | | | | | | | | | | | | |
12/3/25 17:08 | 12/1/25 | LGND | Ligand Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Kozarich John W | FL | D | | S | -91 | 195.84 | 0 | 0 | -1 | 44 | D | | | | | | | | | | | | | | |
12/3/25 17:05 | 12/2/25 | ENTA | Enanta Pharmaceuticals Inc | | Health | Drug | Pharmaceutical Preparations | Trout Harry R. III | MA | O | See Rema | S | -5 | 13.96 | 0 | 0 | -2 | 17 | D | | | | | | | | | | | | | | |
12/3/25 17:02 | 12/1/25 | NUVB | Nuvation Bio Inc. | DE | Health | Drug | Pharmaceutical Preparations | Liu Dongfang | NY | O | CHIEF ME | S.d | -1,173 | 7.82 | 0 | -150 | -89 | 18 | D | | | | | | | | | | | | | | |
12/3/25 16:39 | 12/1/25 | AMLX | Amylyx Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Bedrosian Camille L | MA | O | Chief Me | S | -94 | 14.35 | 0 | -7 | -4 | 176 | D | | | | | | | | | | | | | | |
12/3/25 16:30 | 12/1/25 | TVTX | Travere Therapeutics, Inc. | CA | Health | Drug | Pharmaceutical Preparations | Cline Christopher R. | CA | O | CFO | S.d | -700 | 35.01 | 0 | -20 | -18 | 92 | D | | | | | | | | | | | | | | |
12/3/25 16:28 | 12/1/25 | CRNX | Crinetics Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Pizzuti Dana | CA | O | Chief Me | S.d | -225 | 45.02 | 0 | -5 | -7 | 67 | D | | | | | | | | | | | | | | |
12/3/25 16:01 | 12/1/25 | INSM | Insmed Inc | VA | Health | Drug | Pharmaceutical Preparations | Flammer Martina M.D. | NJ | O | Chief Me | S.d | -1,841 | 206.98 | 0 | -9 | -10 | 83 | D | | | | | | | | | | | | | | |
12/2/25 19:00 | 12/1/25 | GNLX | Genelux Corp | DE | Health | Drug | Pharmaceutical Preparations | Thomas John | CA | D | | S | -50 | 5.00 | 0 | -10 | -2 | 493 | D | | | | | | | | | | | | | | |
12/2/25 17:14 | 12/1/25 | XERS | Xeris Biopharma Holdings, Inc. | | Health | Drug | Pharmaceutical Preparations | Hecht Beth | IL | O | See Rema | S | -117 | 7.01 | 0 | -17 | -1 | 1,320 | D | | | | | | | | | | | | | | |
12/2/25 17:14 | 12/2/25 | CYTK | Cytokinetics Inc | | Health | Drug | Pharmaceutical Preparations | Henderson John T | CA | D | | S.d | -559 | 63.90 | 0 | -9 | -10 | 75 | D | | | | | | | | | | | | | | |
12/2/25 17:10 | 12/2/25 | CYTK | Cytokinetics Inc | | Health | Drug | Pharmaceutical Preparations | Malik Fady Ibraham | CA | O | EVP Rese | S.d | -141 | 63.89 | 0 | -2 | -2 | 141 | D | | | | | | | | | | | | | | |
12/2/25 16:43 | 11/28/25 | PBH | Prestige Consumer Healthcare Inc. | | Health | Drug | Pharmaceutical Preparations | Zerillo Jeffrey | NY | O | SVP Oper | S.m | -60 | 60.00 | 0 | -1 | -2 | 42 | D | | | | | | | | | | | | | | |
12/2/25 16:34 | 12/1/25 | LQDA | Liquidia Corp | DE | Health | Drug | Pharmaceutical Preparations | Schundler Russell | NC | O | GC | S.d | -35 | 32.19 | 0 | -1 | 0 | 592 | D | | | | | | | | | | | | | | |
12/2/25 16:33 | 12/1/25 | LQDA | Liquidia Corp | DE | Health | Drug | Pharmaceutical Preparations | Krepp Sarah | NC | O | Chief Hu | S | -7 | 32.19 | 0 | 0 | 0 | 141 | D | | | | | | | | | | | | | | |
12/2/25 16:32 | 12/1/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Edgemond James | MD | O | CFO,TREA | S.d | -10,080 | 479.99 | 0 | -21 | -72 | 8 | D | | | | | | | | | | | | | | |
12/2/25 16:32 | 12/1/25 | LQDA | Liquidia Corp | DE | Health | Drug | Pharmaceutical Preparations | Kaseta Michael | NC | O | CFO,COO | S.d | -38 | 32.19 | 0 | -1 | 0 | 354 | D | | | | | | | | | | | | | | |
12/2/25 16:32 | 12/1/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Rothblatt Martine A | MD | DO | CHAIRPER | S.dm | -3,853 | 481.61 | 0 | -8 | -1 | 644 | D | | | | | | | | | | | | | | |
12/2/25 16:31 | 12/1/25 | LQDA | Liquidia Corp | DE | Health | Drug | Pharmaceutical Preparations | Boyle Dana | NC | O | Chief Ac | S | -10 | 32.19 | 0 | 0 | 0 | 155 | D | | | | | | | | | | | | | | |
12/2/25 16:31 | 12/1/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Benkowitz Michael | MD | O | P,COO | S.d | -10,798 | 479.92 | 0 | -23 | -89 | 3 | I | | | | | | | | | | | | | | |
12/2/25 16:31 | 12/1/25 | LQDA | Liquidia Corp | DE | Health | Drug | Pharmaceutical Preparations | Adair Jason | NC | O | Chief Bu | S.d | -22 | 32.19 | 0 | -1 | 0 | 176 | D | | | | | | | | | | | | | | |
12/2/25 16:30 | 11/28/25 | NUVL | Nuvalent, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Noci Darlene | MA | O | Chief De | S.d | -434 | 108.58 | 0 | -4 | -8 | 48 | D | | | | | | | | | | | | | | |
12/2/25 16:30 | 12/1/25 | LQDA | Liquidia Corp | DE | Health | Drug | Pharmaceutical Preparations | Moomaw Scott | NC | O | Chief Co | S.d | -27 | 32.19 | 0 | -1 | -1 | 155 | D | | | | | | | | | | | | | | |
12/2/25 16:15 | 11/28/25 | PAHC | Phibro Animal Health Corp | DE | Health | Drug | Pharmaceutical Preparations | Bendheim Jack | NJ | DOT | P,CEO | S.m | -296 | 42.10 | 0 | -7 | -14 | 44 | I | | | | | | | | | | | | | | |
12/2/25 16:04 | 12/1/25 | MIRM | Mirum Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Grey Michael G | CA | D | | S.d | -3,700 | 74.00 | 0 | -50 | -15 | 280 | D | | | | | | | | | | | | | | |
12/2/25 09:18 | 12/1/25 | CYTK | Cytokinetics Inc | | Health | Drug | Pharmaceutical Preparations | Kaye Edward M. Md | CA | D | | S.d | -1,872 | 66.72 | 0 | -28 | -74 | 10 | D | | | | | | | | | | | | | | |
12/2/25 09:13 | 12/1/25 | CYTK | Cytokinetics Inc | | Health | Drug | Pharmaceutical Preparations | Harrington Robert Arthur | CA | D | | S | -144 | 66.80 | 0 | -2 | -10 | 19 | D | | | | | | | | | | | | | | |
12/1/25 19:02 | 11/26/25 | TBPH | Theravance Biopharma, Inc. | CA | Health | Drug | Pharmaceutical Preparations | Broshy Eran | CA | D | | S.d | -590 | 20.00 | 0 | -30 | -40 | 45 | D | | | | | | | | | | | | | | |
12/1/25 18:14 | 11/26/25 | JAZZ | Jazz Pharmaceuticals Plc | L2 | Health | Drug | Pharmaceutical Preparations | Cozadd Bruce C | L2 | D | | S.d | -13,780 | 177.81 | 0 | -78 | -16 | 393 | D | | | | | | | | | | | | | | |
12/1/25 18:13 | 11/26/25 | HOWL | Werewolf Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Evnin Luke | MA | D | | S.m | -88 | 0.9643 | 0 | -91 | -3 | 3,196 | I | | | | | | | | | | | | | | |
12/1/25 18:12 | 11/26/25 | HOWL | Werewolf Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Mpm Bioventures 2014, L.P. | MA | T | | S.m | -137 | 0.9643 | 0 | -142 | -3 | 4,984 | I | | | | | | | | | | | | | | |
12/1/25 18:11 | 11/26/25 | HOWL | Werewolf Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Gadicke Ansbert | MA | T | | S.m | -137 | 0.9643 | 0 | -142 | -3 | 4,984 | I | | | | | | | | | | | | | | |
12/1/25 18:10 | 11/28/25 | ARWR | Arrowhead Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Ferrari Mauro | CA | D | | S | -493 | 56.39 | 0 | -9 | -11 | 69 | D | | | | | | | | | | | | | | |
12/1/25 18:09 | 11/26/25 | RCUS | Arcus Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Azoy Alexander | CA | O | Chief Ac | S.d | -49 | 26.00 | 0 | -2 | -6 | 27 | D | | | | | | | | | | | | | | |
12/1/25 17:41 | 12/1/25 | ALKS | Alkermes Plc. | | Health | Drug | Pharmaceutical Preparations | Hopkinson Craig C. | MA | O | EVP R,D, | S | -117 | 29.30 | 0 | -4 | -6 | 66 | D | | | | | | | | | | | | | | |
12/1/25 16:57 | 11/26/25 | ONC | Beone Medicines Ltd. | | Health | Drug | Pharmaceutical Preparations | Sanders Corazon (Corsee) D. | V8 | D | | S.d | -896 | 340.90 | 0 | -3 | -4 | 57 | D | | | | | | | | | | | | | | |
12/1/25 16:40 | 11/26/25 | VSTM | Verastem, Inc. | MA | Health | Drug | Pharmaceutical Preparations | Paterson Dan | MA | DO | P,CEO | S.m | -63 | 10.50 | 0 | -6 | -1 | 427 | D | | | | | | | | | | | | | | |
12/1/25 16:37 | 11/26/25 | KNSA | Kiniksa Pharmaceuticals International, Plc | | Health | Drug | Pharmaceutical Preparations | Tessari Eben | X0 | O | COO | S.d | -9 | 42.89 | 0 | 0 | -1 | 23 | D | | | | | | | | | | | | | | |
12/1/25 16:31 | 11/26/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Rothblatt Martine A | MD | DO | CHAIRPER | S.dm | -3,891 | 486.34 | 0 | -8 | -1 | 644 | D | | | | | | | | | | | | | | |
12/1/25 16:17 | 11/26/25 | RAPP | Rapport Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Gault Cheryl | MA | O | COO | S.d | -150 | 30.10 | 0 | -5 | -3 | 172 | D | | | | | | | | | | | | | | |
12/1/25 16:07 | 11/26/25 | CVRX | Cvrx, Inc. | NJ | Health | Drug | Pharmaceutical Preparations | Johnson & Johnson | NJ | T | | S | -64 | 10.03 | 0 | -6 | 0 | 4,041 | I | | | | | | | | | | | | | | |
12/1/25 16:02 | 11/26/25 | TEVA | Teva Pharmaceutical Industries Ltd | L3 | Health | Drug | Pharmaceutical Preparations | Mignone Roberto | L3 | D | | S | -1,302 | 26.03 | 0 | -50 | -8 | 550 | I | | | | | | | | | | | | | | |
11/28/25 17:51 | 11/25/25 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Klein Joseph III | CA | D | | S.d | -960 | 80.00 | 0 | -12 | -42 | 16 | I | | | | | | | | | | | | | | |
11/28/25 17:51 | 11/25/25 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Devers Shannon L. | CA | O | EVP,Chie | S.d | -1,357 | 80.91 | 0 | -17 | -49 | 17 | D | | | | | | | | | | | | | | |
11/28/25 17:00 | 11/26/25 | CPRX | Catalyst Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Del Carmen Jeffrey | FL | O | Chief Co | S.d | -256 | 23.33 | 0 | -11 | -73 | 4 | D | | | | | | | | | | | | | | |
11/28/25 16:05 | 11/25/25 | MRUS | Merus N.V. | P7 | Health | Drug | Pharmaceutical Preparations | Shuman Harry | P7 | O | VP Contr | S.d | -796 | 95.92 | 0 | -8 | -43 | 11 | D | | | | | | | | | | | | | | |
11/26/25 21:30 | 11/24/25 | CRMD | Cormedix Inc. | DE | Health | Drug | Pharmaceutical Preparations | Dillione Janet | NJ | D | | S.d | -262 | 9.93 | 0 | -26 | -35 | 48 | D | | | | | | | | | | | | | | |
11/26/25 21:18 | 11/24/25 | FOLD | Amicus Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Castelli Jeff | NJ | O | Chief De | S.d | -774 | 10.16 | 0 | -76 | -15 | 439 | D | | | | | | | | | | | | | | |
11/26/25 21:17 | 11/24/25 | FOLD | Amicus Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Clark David Michael | NJ | O | Chief Pe | S | -259 | 10.10 | 0 | -26 | -8 | 297 | D | | | | | | | | | | | | | | |
11/26/25 21:17 | 11/24/25 | FOLD | Amicus Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Campbell Bradley L | NJ | DO | P,CEO | S.d | -147 | 10.04 | 0 | -15 | -1 | 1,137 | D | | | | | | | | | | | | | | |
11/26/25 21:16 | 11/24/25 | FOLD | Amicus Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Rosenberg Ellen | NJ | O | GC | S.dm | -958 | 10.02 | 0 | -96 | -15 | 523 | D | | | | | | | | | | | | | | |
11/26/25 18:50 | 11/24/25 | KALV | Kalvista Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Piekos Brian | MA | O | CFO | S.d | -60 | 13.45 | 0 | -4 | -30 | 11 | D | | | | | | | | | | | | | | |
11/26/25 18:49 | 11/24/25 | KALV | Kalvista Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Yea Christopher | MA | O | CHIEF DE | S.d | -58 | 13.45 | 0 | -4 | -2 | 224 | D | | | | | | | | | | | | | | |
11/26/25 18:47 | 11/24/25 | KALV | Kalvista Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Audhya Paul K. | MA | O | CHIEF ME | S.d | -71 | 13.45 | 0 | -5 | -4 | 132 | D | | | | | | | | | | | | | | |
11/26/25 18:46 | 11/24/25 | KALV | Kalvista Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Palleiko Benjamin L | MA | DO | CEO | S.d | -147 | 13.45 | 0 | -11 | -3 | 416 | D | | | | | | | | | | | | | | |
11/26/25 18:45 | 11/24/25 | SION | Sionna Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Orbimed Advisors LLC | NY | D | | S.m | -4,814 | 44.55 | 0 | -108 | -3 | 3,597 | I | | | | | | | | | | | | | | |
11/26/25 18:41 | 11/24/25 | SION | Sionna Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Thompson Peter A. | MA | D | | S.m | -4,814 | 44.55 | 0 | -108 | -3 | 3,597 | I | | | | | | | | | | | | | | |
11/26/25 18:24 | 11/24/25 | ORGO | Organogenesis Holdings Inc. | DE | Health | Drug | Pharmaceutical Preparations | Nussdorf Glenn H | NY | DT | | S.m | -1,592 | 5.31 | 0 | -300 | -2 | 11,949 | D | | | | | | | | | | | | | | |
11/26/25 17:55 | 11/25/25 | NUVB | Nuvation Bio Inc. | DE | Health | Drug | Pharmaceutical Preparations | Liu Dongfang | NY | O | CHIEF ME | S.dm | -155 | 7.75 | 0 | -20 | -53 | 18 | D | | | | | | | | | | | | | | |
11/26/25 17:46 | 11/25/25 | PAHC | Phibro Animal Health Corp | DE | Health | Drug | Pharmaceutical Preparations | Bendheim Jack | NJ | DOT | P,CEO | S.m | -542 | 43.97 | 0 | -12 | -20 | 51 | I | | | | | | | | | | | | | | |
11/26/25 17:22 | 11/25/25 | CORT | Corcept Therapeutics Inc | DE | Health | Drug | Pharmaceutical Preparations | Guyer William | CA | O | Chief De | S | -364 | 80.90 | 0 | -5 | -85 | 1 | D | | | | | | | | | | | | | | |
11/26/25 17:21 | 11/25/25 | SER | Serina Therapeutics, Inc. | AL | Health | Drug | Pharmaceutical Preparations | Moreadith Randall | AL | O | Chief Sc | S.d | -23 | 3.90 | 0 | -6 | -50 | 6 | D | | | | | | | | | | | | | | |
11/26/25 17:01 | 11/24/25 | RPRX | Royalty Pharma Plc | X0 | Health | Drug | Pharmaceutical Preparations | Coyne Terrance P. | NY | O | EVP,CFO | S | -2,683 | 38.55 | 0 | -70 | -8 | 760 | I | | | | | | | | | | | | | | |
11/26/25 16:31 | 11/24/25 | INSM | Insmed Inc | VA | Health | Drug | Pharmaceutical Preparations | Anderson Elizabeth M | NJ | D | | S | -1,023 | 204.58 | 0 | -5 | -8 | 59 | D | | | | | | | | | | | | | | |
11/26/25 16:31 | 11/24/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Edgemond James | MD | O | CFO,TREA | S.d | -9,947 | 473.65 | 0 | -21 | -72 | 8 | D | | | | | | | | | | | | | | |
11/26/25 16:30 | 11/24/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Benkowitz Michael | MD | O | P,COO | S.d | -10,657 | 473.66 | 0 | -23 | -89 | 3 | I | | | | | | | | | | | | | | |
11/26/25 16:30 | 11/26/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Mahon Paul A | MD | O | EVP,GC | S.d | -5,347 | 486.06 | 0 | -11 | -23 | 37 | D | | | | | | | | | | | | | | |
11/26/25 16:30 | 11/25/25 | ADTX | Aditxt, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Pankovcin Corinne | CA | O | Chief M, | S | 0 | 3.20 | 0 | 0 | -100 | 0 | D | | | | | | | | | | | | | | |
11/26/25 16:30 | 11/24/25 | NUVL | Nuvalent, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Shair Matthew | MA | D | | S | -820 | 109.37 | 0 | -8 | 0 | 1,579 | M | | | | | | | | | | | | | | |
11/26/25 16:07 | 11/26/25 | RCUS | Arcus Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Goeltz II Robert C. | CA | O | CFO | S | -125 | 25.00 | 0 | -5 | -5 | 87 | D | | | | | | | | | | | | | | |
11/26/25 16:06 | 11/24/25 | STOK | Stoke Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Krainer Adrian R. | MA | D | | S | -1,203 | 29.72 | 0 | -40 | -11 | 324 | D | | | | | | | | | | | | | | |
11/26/25 16:02 | 11/24/25 | OCUL | Ocular Therapeutix, Inc | DE | Health | Drug | Pharmaceutical Preparations | Nayak Sanjay | MA | O | Chief St | S | -23 | 12.04 | 0 | -2 | -1 | 278 | D | | | | | | | | | | | | | | |
11/26/25 16:02 | 11/24/25 | OCUL | Ocular Therapeutix, Inc | DE | Health | Drug | Pharmaceutical Preparations | Dugel Pravin | MA | DO | See Rema | S | -235 | 12.04 | 0 | -20 | -1 | 3,458 | M | | | | | | | | | | | | | | |
11/26/25 16:01 | 11/24/25 | OCUL | Ocular Therapeutix, Inc | DE | Health | Drug | Pharmaceutical Preparations | Kaiser Peter | MA | O | Chief De | S | -36 | 12.02 | 0 | -3 | -2 | 191 | D | | | | | | | | | | | | | | |
11/26/25 16:01 | 11/24/25 | OCUL | Ocular Therapeutix, Inc | DE | Health | Drug | Pharmaceutical Preparations | Heier Jeffrey S. | MA | O | Chief Sc | S | -42 | 12.04 | 0 | -3 | -1 | 246 | D | | | | | | | | | | | | | | |
11/26/25 16:00 | 11/25/25 | LLY | Eli Lilly & Co | IN | Health | Drug | Pharmaceutical Preparations | Lilly Endowment Inc | IN | T | | S.e | -3 | 0.2129 | 0 | -16 | 0 | 92,197 | D | | | | | | | | | | | | | | |
11/26/25 16:00 | 11/25/25 | LLY | Eli Lilly & Co | IN | Health | Drug | Pharmaceutical Preparations | Lilly Endowment Inc | IN | T | | S.e | -33 | 0.2228 | 0 | -147 | 0 | 92,213 | D | | | | | | | | | | | | | | |
11/25/25 21:20 | 11/24/25 | SER | Serina Therapeutics, Inc. | AL | Health | Drug | Pharmaceutical Preparations | Moreadith Randall | AL | O | Chief Sc | S.d | -2 | 3.94 | 0 | -1 | -100 | 0 | D | | | | | | | | | | | | | | |
11/25/25 20:30 | 11/25/25 | NKTR | Nektar Therapeutics | DE | Health | Drug | Pharmaceutical Preparations | Zalevsky Jonathan | CA | O | Chief R, | S.d | -63 | 54.28 | 0 | -1 | -6 | 19 | D | | | | | | | | | | | | | | |
11/25/25 20:29 | 11/25/25 | NKTR | Nektar Therapeutics | DE | Health | Drug | Pharmaceutical Preparations | Wilson Mark Andrew | CA | O | GC | S.d | -34 | 54.28 | 0 | -1 | -3 | 22 | D | | | | | | | | | | | | | | |
11/25/25 20:28 | 11/25/25 | NKTR | Nektar Therapeutics | DE | Health | Drug | Pharmaceutical Preparations | Robin Howard W | CA | DO | P,CEO | S.d | -120 | 54.28 | 0 | -2 | -4 | 54 | D | | | | | | | | | | | | | | |
11/25/25 19:38 | 11/25/25 | AMPH | Amphastar Pharmaceuticals, Inc. | | Health | Drug | Pharmaceutical Preparations | Prins Richard K | CA | D | | S.d | -113 | 27.10 | 0 | -4 | -11 | 35 | D | | | | | | | | | | | | | | |
11/25/25 18:42 | 11/21/25 | BCAX | Bicara Therapeutics Inc. | DE | Health | Drug | Pharmaceutical Preparations | Hyep Ivan | MA | O | CFO | S.dm | -341 | 18.54 | 0 | -18 | -11 | 145 | D | | | | | | | | | | | | | | |
11/25/25 18:41 | 11/21/25 | BCAX | Bicara Therapeutics Inc. | DE | Health | Drug | Pharmaceutical Preparations | Cohlhepp Ryan | MA | DO | P,COO | S.d | -226 | 18.05 | 0 | -13 | -6 | 194 | D | | | | | | | | | | | | | | |
11/25/25 18:40 | 11/24/25 | BCAX | Bicara Therapeutics Inc. | DE | Health | Drug | Pharmaceutical Preparations | Mazumdar Claire | MA | DO | CEO | S.d | -776 | 18.86 | 0 | -41 | -12 | 310 | D | | | | | | | | | | | | | | |
11/25/25 18:39 | 11/24/25 | BCAX | Bicara Therapeutics Inc. | DE | Health | Drug | Pharmaceutical Preparations | Raben David | MA | O | Chief Me | S.dm | -205 | 18.65 | 0 | -11 | -24 | 35 | D | | | | | | | | | | | | | | |
11/25/25 18:27 | 11/24/25 | ARQT | Arcutis Biotherapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Lin Sue-Jean | CA | D | | S.d | -778 | 30.78 | 0 | -25 | -49 | 27 | D | | | | | | | | | | | | | | |
11/25/25 18:08 | 11/25/25 | EQ | Equillium, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Zedelmayer Christine | CA | O | SVP,COO | S | -8 | 0.9504 | 0 | -8 | -6 | 127 | D | | | | | | | | | | | | | | |
11/25/25 18:05 | 11/21/25 | HOWL | Werewolf Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Evnin Luke | MA | D | | S.m | -115 | 0.9176 | 0 | -126 | -4 | 3,288 | I | | | | | | | | | | | | | | |
11/25/25 18:04 | 11/21/25 | HOWL | Werewolf Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Mpm Bioventures 2014, L.P. | MA | T | | S.m | -180 | 0.9176 | 0 | -196 | -4 | 5,126 | I | | | | | | | | | | | | | | |
11/25/25 18:03 | 11/21/25 | HOWL | Werewolf Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Gadicke Ansbert | MA | T | | S.m | -180 | 0.9176 | 0 | -196 | -4 | 5,126 | I | | | | | | | | | | | | | | |
11/25/25 17:35 | 11/21/25 | VSTM | Verastem, Inc. | MA | Health | Drug | Pharmaceutical Preparations | Bunn Paul A. | MA | D | | S.d | -63 | 10.00 | 0 | -6 | -43 | 8 | D | | | | | | | | | | | | | | |
11/25/25 17:34 | 11/21/25 | VSTM | Verastem, Inc. | MA | Health | Drug | Pharmaceutical Preparations | Kauffman Michael | MA | D | | S | -86 | 10.00 | 0 | -9 | -50 | 9 | D | | | | | | | | | | | | | | |
11/25/25 17:32 | 11/21/25 | VSTM | Verastem, Inc. | MA | Health | Drug | Pharmaceutical Preparations | Paterson Dan | MA | DO | P,CEO | S.m | -60 | 10.00 | 0 | -6 | -1 | 433 | D | | | | | | | | | | | | | | |
11/25/25 17:31 | 11/24/25 | TGTX | Tg Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Echelard Yann | NC | D | | S | -163 | 32.57 | 0 | -5 | -2 | 224 | D | | | | | | | | | | | | | | |
11/25/25 17:00 | 11/21/25 | TYRA | Tyra Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | More Robert J | CA | D | | S | -5,000 | 20.25 | 0 | -247 | -6 | 3,833 | I | | | | | | | | | | | | | | |
11/25/25 16:49 | 11/24/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Rothblatt Martine A | MD | DO | CHAIRPER | S.dm | -3,784 | 473.05 | 0 | -8 | -1 | 644 | D | | | | | | | | | | | | | | |
11/25/25 16:44 | 11/21/25 | ARDX | Ardelyx, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Grammer Elizabeth A | MA | O | See Rema | S | -33 | 5.54 | 0 | -6 | -2 | 300 | D | | | | | | | | | | | | | | |
11/25/25 16:42 | 11/21/25 | ARDX | Ardelyx, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Raab Michael | MA | DO | P,CEO | S | -260 | 5.54 | 0 | -47 | -3 | 1,481 | D | | | | | | | | | | | | | | |
11/25/25 16:38 | 11/21/25 | ARDX | Ardelyx, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kelliher Mike | MA | O | See Rema | S | -31 | 5.54 | 0 | -6 | -2 | 271 | D | | | | | | | | | | | | | | |
11/25/25 16:35 | 11/21/25 | ARDX | Ardelyx, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Williams Laura A | MA | O | Chief Pa | S | -36 | 5.54 | 0 | -6 | -2 | 360 | D | | | | | | | | | | | | | | |
11/25/25 16:22 | 11/21/25 | ARDX | Ardelyx, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Foster Eric Duane | MA | O | Chief Co | S | -32 | 5.54 | 0 | -6 | -2 | 296 | D | | | | | | | | | | | | | | |
11/25/25 16:21 | 11/21/25 | ARDX | Ardelyx, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Reilly Joseph James | MA | O | See Rema | S | -61 | 5.54 | 0 | -11 | -9 | 109 | D | | | | | | | | | | | | | | |
11/25/25 16:17 | 11/25/25 | ABT | Abbott Laboratories | IL | Health | Drug | Pharmaceutical Preparations | Shroff Eric | IL | O | SVP | S | -203 | 128.02 | 0 | -2 | -5 | 30 | D | | | | | | | | | | | | | | |
11/25/25 16:11 | 11/21/25 | ZLAB | Zai Lab Ltd | E9 | Health | Drug | Pharmaceutical Preparations | Edmondson Frazor Titus III | MA | O | GC | S | -283 | 19.78 | 0 | -14 | -34 | 28 | D | | | | | | | | | | | | | | |
11/25/25 16:10 | 11/21/25 | MIRM | Mirum Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Grey Michael G | CA | D | | S.d | -3,500 | 70.00 | 0 | -50 | -15 | 280 | D | | | | | | | | | | | | | | |
11/25/25 16:10 | 11/21/25 | HRMY | Harmony Biosciences Holdings, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kapadia Sandip | PA | O | CFO | S | -120 | 35.00 | 0 | -3 | -100 | 0 | D | | | | | | | | | | | | | | |
11/25/25 16:05 | 11/21/25 | VERA | Vera Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Carter Jason S | CA | O | GC | S | -107 | 27.82 | 0 | -4 | -7 | 49 | D | | | | | | | | | | | | | | |
11/25/25 16:00 | 11/24/25 | LLY | Eli Lilly & Co | IN | Health | Drug | Pharmaceutical Preparations | Lilly Endowment Inc | IN | T | | S.e | -6 | 0.0452 | 0 | -142 | 0 | 92,360 | D | | | | | | | | | | | | | | |
11/25/25 12:54 | 11/21/25 | CVRX | Cvrx, Inc. | NJ | Health | Drug | Pharmaceutical Preparations | Johnson & Johnson | NJ | T | | S.m | -27 | 10.05 | 0 | -3 | 0 | 4,047 | I | | | | | | | | | | | | | | |
11/24/25 20:00 | 11/24/25 | NUVL | Nuvalent, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Flynn James E | NY | DTH | Director | S | -70,875 | 95.45 | 0 | -743 | -4 | 17,248 | I | | | | | | | | | | | | | | |
11/24/25 18:46 | 11/20/25 | BBIO | Bridgebio Pharma, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kumar Neil | CA | DO | CEO | S | -1,722 | 65.84 | 0 | -26 | 0 | 5,623 | D | | | | | | | | | | | | | | |
11/24/25 18:45 | 11/21/25 | ARQT | Arcutis Biotherapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Watanabe Todd | CA | DO | See Rema | S.m | -1,517 | 30.35 | 0 | -50 | -5 | 974 | D | | | | | | | | | | | | | | |
11/24/25 18:06 | 11/24/25 | NRIX | Nurix Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Ring Christine | CA | O | GC | S.d | -642 | 17.07 | 0 | -38 | -42 | 51 | D | | | | | | | | | | | | | | |
11/24/25 17:47 | 11/20/25 | JAZZ | Jazz Pharmaceuticals Plc | L2 | Health | Drug | Pharmaceutical Preparations | McSharry Heather Ann | L2 | D | | S.d | -607 | 177.78 | 0 | -3 | -14 | 20 | D | | | | | | | | | | | | | | |
11/24/25 17:43 | 11/20/25 | SION | Sionna Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Ra Capital Management, L.P. | MA | DT | | S.m | -1,201 | 39.61 | 0 | -30 | -16 | 159 | I | | | | | | | | | | | | | | |
11/24/25 16:42 | 11/20/25 | GRTX | Galera Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Sorensen Mel | PA | DO | P,CEO | S | -1 | 0.0201 | 0 | -70 | -26 | 195 | D | | | | | | | | | | | | | | |
11/24/25 16:30 | 11/21/25 | TRDA | Entrada Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Wentworth Kory James | MA | O | CFO | S | -89 | 9.98 | 0 | -9 | -7 | 110 | D | | | | | | | | | | | | | | |
11/24/25 16:15 | 11/20/25 | RYTM | Rhythm Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Cramer Pamela J. | MA | O | CHRO | S.d | -352 | 105.00 | 0 | -3 | -14 | 21 | D | | | | | | | | | | | | | | |
11/24/25 16:15 | 11/20/25 | PAHC | Phibro Animal Health Corp | DE | Health | Drug | Pharmaceutical Preparations | Bendheim Jack | NJ | DOT | P,CEO | S | -147 | 41.76 | 0 | -4 | -5 | 63 | I | | | | | | | | | | | | | | |
11/24/25 16:09 | 11/20/25 | NUVB | Nuvation Bio Inc. | DE | Health | Drug | Pharmaceutical Preparations | Hattersley Gary | NY | O | Chief Sc | S.d | -2,667 | 7.23 | 0 | -369 | -100 | 0 | D | | | | | | | | | | | | | | |
11/24/25 16:08 | 11/20/25 | NUVB | Nuvation Bio Inc. | DE | Health | Drug | Pharmaceutical Preparations | Liu Dongfang | NY | O | CHIEF ME | S.d | -140 | 7.00 | 0 | -20 | -53 | 18 | D | | | | | | | | | | | | | | |
11/24/25 16:05 | 11/20/25 | REGN | Regeneron Pharmaceuticals, Inc. | NY | Health | Drug | Pharmaceutical Preparations | Bassler Bonnie L | NY | D | | S.d | -570 | 750.00 | 0 | -1 | -33 | 2 | D | | | | | | | | | | | | | | |
11/24/25 16:03 | 11/20/25 | TEVA | Teva Pharmaceutical Industries Ltd | L3 | Health | Drug | Pharmaceutical Preparations | Fox Christine | L3 | O | EVP,Head | S.d | -700 | 24.78 | 0 | -28 | -31 | 64 | D | | | | | | | | | | | | | | |
11/24/25 16:00 | 11/21/25 | LLY | Eli Lilly & Co | IN | Health | Drug | Pharmaceutical Preparations | Lilly Endowment Inc | IN | T | | S.e | -18 | 0.1708 | 0 | -105 | 0 | 92,502 | D | | | | | | | | | | | | | | |
11/21/25 21:41 | 11/20/25 | PRAX | Praxis Precision Medicines, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Nemiroff Alex | MA | O | GC,Secre | S.d | -4,852 | 193.09 | 0 | -25 | -55 | 21 | D | | | | | | | | | | | | | | |
11/21/25 21:39 | 11/20/25 | PRAX | Praxis Precision Medicines, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Mastrocola Lauren | MA | O | Principa | S.d | -2,612 | 192.08 | 0 | -14 | -57 | 10 | D | | | | | | | | | | | | | | |
11/21/25 20:24 | 11/19/25 | ROIV | Roivant Sciences Ltd. | D0 | Health | Drug | Pharmaceutical Preparations | Manchester Keith S | X0 | D | | S | -26,305 | 20.23 | 0 | -1,300 | -7 | 18,048 | I | | | | | | | | | | | | | | |
11/21/25 20:22 | 11/19/25 | ROIV | Roivant Sciences Ltd. | D0 | Health | Drug | Pharmaceutical Preparations | Gold Daniel Allen | X0 | D | | S | -26,305 | 20.23 | 0 | -1,300 | -7 | 18,048 | I | | | | | | | | | | | | | | |
11/21/25 20:15 | 11/19/25 | ROIV | Roivant Sciences Ltd. | D0 | Health | Drug | Pharmaceutical Preparations | Qvt Financial LP | NY | H | Director | S | -26,305 | 20.23 | 0 | -1,300 | -7 | 18,048 | I | | | | | | | | | | | | | | |
11/21/25 19:54 | 11/19/25 | PGEN | Precigen, Inc. | VA | Health | Drug | Pharmaceutical Preparations | Kirk Randal J | VA | DT | | S.m | -12,292 | 4.14 | 0 | -2,966 | -2 | 123,946 | I | | | | | | | | | | | | | | |
11/21/25 18:34 | 11/19/25 | ARQT | Arcutis Biotherapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Matsuda Masaru | CA | O | See Rema | S | -72 | 28.29 | 0 | -3 | -2 | 151 | D | | | | | | | | | | | | | | |
11/21/25 18:21 | 11/20/25 | ARQT | Arcutis Biotherapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Gilbert Halley E | CA | D | | S.d | -455 | 27.55 | 0 | -17 | -43 | 22 | D | | | | | | | | | | | | | | |
11/21/25 18:13 | 11/20/25 | SGMT | Sagimet Biosciences Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kemble George | CA | DO | Exec CB | S | -290 | 7.69 | 0 | -38 | -32 | 81 | D | | | | | | | | | | | | | | |
11/21/25 18:07 | 11/20/25 | MLYS | Mineralys Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Slingsby Brian Taylor | WA | DT | | S | -43,350 | 43.35 | 0 | -1,000 | -11 | 7,904 | I | | | | | | | | | | | | | | |
11/21/25 17:39 | 11/21/25 | MDGL | Madrigal Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Huntsman Carole | PA | O | Chief Co | S | -1,083 | 553.11 | 0 | -2 | -16 | 10 | D | | | | | | | | | | | | | | |
11/21/25 17:28 | 11/19/25 | ELVN | Enliven Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Lyssikatos Joseph P | CO | O | CHIEF SC | S | -279 | 22.33 | 0 | -13 | -1 | 903 | I | | | | | | | | | | | | | | |
11/21/25 17:26 | 11/20/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Rothblatt Martine A | MD | DO | CHAIRPER | S.dm | -3,812 | 476.51 | 0 | -8 | -1 | 644 | D | | | | | | | | | | | | | | |
11/21/25 16:59 | 11/19/25 | LFVN | Lifevantage Corp | | Health | Drug | Pharmaceutical Preparations | Beindorff Michael A | UT | D | | S | -81 | 6.42 | 0 | -13 | -13 | 85 | I | | | | | | | | | | | | | | |
11/21/25 16:55 | 11/19/25 | RPRX | Royalty Pharma Plc | X0 | Health | Drug | Pharmaceutical Preparations | Lloyd George W. | NY | O | EVP,Inve | S | -5,193 | 38.34 | 0 | -135 | -12 | 1,000 | M | | | | | | | | | | | | | | |
11/21/25 16:25 | 11/19/25 | PVLA | Palvella Therapeutics, Inc. | NV | Health | Drug | Pharmaceutical Preparations | Goin Kathleen | PA | O | COO | S.d | -371 | 86.23 | 0 | -4 | -100 | 0 | D | | | | | | | | | | | | | | |
11/21/25 16:15 | 11/19/25 | FULC | Fulcrum Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Gould Robert J | MA | D | | S | -165 | 11.03 | 0 | -15 | -3 | 485 | D | | | | | | | | | | | | | | |
11/21/25 16:05 | 11/19/25 | NUVB | Nuvation Bio Inc. | DE | Health | Drug | Pharmaceutical Preparations | Hanley David C. | NY | O | CHIEF TE | S.d | -1,428 | 7.14 | 0 | -200 | -89 | 24 | D | | | | | | | | | | | | | | |
11/21/25 16:00 | 11/20/25 | LLY | Eli Lilly & Co | IN | Health | Drug | Pharmaceutical Preparations | Lilly Endowment Inc | IN | T | | S.e | -6 | 0.1701 | 0 | -37 | 0 | 92,607 | D | | | | | | | | | | | | | | |
11/20/25 20:03 | 11/18/25 | JAZZ | Jazz Pharmaceuticals Plc | L2 | Health | Drug | Pharmaceutical Preparations | Cozadd Bruce C | L2 | D | | S | -3,260 | 181.09 | 0 | -18 | -4 | 393 | D | | | | | | | | | | | | | | |
11/20/25 18:13 | 11/18/25 | JAZZ | Jazz Pharmaceuticals Plc | L2 | Health | Drug | Pharmaceutical Preparations | Carr Patricia | L2 | O | SVP,Chie | S.d | -968 | 182.07 | 0 | -5 | -43 | 7 | D | | | | | | | | | | | | | | |
11/20/25 17:54 | 11/18/25 | JAZZ | Jazz Pharmaceuticals Plc | L2 | Health | Drug | Pharmaceutical Preparations | Winningham Rick E | L2 | D | | S | -995 | 180.86 | 0 | -6 | -38 | 9 | D | | | | | | | | | | | | | | |
11/20/25 17:52 | 11/18/25 | HOWL | Werewolf Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Evnin Luke | MA | D | | S.m | -95 | 0.9239 | 0 | -103 | -3 | 3,413 | I | | | | | | | | | | | | | | |
11/20/25 17:51 | 11/18/25 | HOWL | Werewolf Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Mpm Bioventures 2014, L.P. | MA | T | | S.m | -148 | 0.9239 | 0 | -160 | -3 | 5,321 | I | | | | | | | | | | | | | | |
11/20/25 17:50 | 11/18/25 | HOWL | Werewolf Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Gadicke Ansbert | MA | T | | S.m | -148 | 0.9239 | 0 | -160 | -3 | 5,321 | I | | | | | | | | | | | | | | |
11/20/25 17:12 | 11/19/25 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Herman Joan E | CA | D | | S.d | -3,174 | 72.13 | 0 | -44 | -49 | 46 | D | | | | | | | | | | | | | | |
11/20/25 16:31 | 11/18/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Rothblatt Martine A | MD | DO | CHAIRPER | S.dm | -3,789 | 473.67 | 0 | -8 | -1 | 644 | D | | | | | | | | | | | | | | |
11/20/25 16:30 | 11/18/25 | LQDA | Liquidia Corp | DE | Health | Drug | Pharmaceutical Preparations | Adair Jason | NC | O | Chief Bu | S.d | -1,071 | 30.03 | 0 | -36 | -17 | 175 | D | | | | | | | | | | | | | | |
11/20/25 16:05 | 11/18/25 | RCKT | Rocket Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Schwartz Jonathan David | NJ | O | See Rema | S | -8 | 2.98 | 0 | -3 | -1 | 299 | D | | | | | | | | | | | | | | |
11/20/25 16:05 | 11/18/25 | RCKT | Rocket Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Shah Gaurav | NJ | DO | CEO | S | -19 | 2.98 | 0 | -6 | -1 | 1,185 | D | | | | | | | | | | | | | | |
11/20/25 16:05 | 11/18/25 | RCKT | Rocket Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Militello John | NJ | O | See Rema | S | -3 | 2.98 | 0 | -1 | -2 | 66 | D | | | | | | | | | | | | | | |
11/20/25 16:05 | 11/18/25 | RCKT | Rocket Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Wilson Martin | NJ | O | GC | S | -5 | 2.98 | 0 | -2 | 0 | 384 | D | | | | | | | | | | | | | | |
11/20/25 16:00 | 11/19/25 | LLY | Eli Lilly & Co | IN | Health | Drug | Pharmaceutical Preparations | Lilly Endowment Inc | IN | T | | S.e | -6 | 0.0377 | 0 | -168 | 0 | 92,644 | D | | | | | | | | | | | | | | |
11/20/25 13:42 | 11/19/25 | URGN | Urogen Pharma Ltd. | L3 | Health | Drug | Pharmaceutical Preparations | Schoenberg Mark | NJ | O | Chief Me | S | -250 | 25.00 | 0 | -10 | -7 | 139 | D | | | | | | | | | | | | | | |
11/19/25 20:43 | 11/17/25 | SION | Sionna Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Ra Capital Management, L.P. | MA | DT | | S.m | -5,500 | 40.34 | 0 | -136 | -45 | 168 | I | | | | | | | | | | | | | | |
11/19/25 20:31 | 11/17/25 | JAZZ | Jazz Pharmaceuticals Plc | L2 | Health | Drug | Pharmaceutical Preparations | Iannone Robert | L2 | O | EVP,Glob | S | -1,205 | 168.26 | 0 | -7 | -9 | 73 | D | | | | | | | | | | | | | | |
11/19/25 19:30 | 11/18/25 | TYRA | Tyra Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Bensen Daniel | CA | O | COO | S.m | -2,031 | 16.17 | 0 | -126 | -42 | 171 | D | | | | | | | | | | | | | | |
11/19/25 18:57 | 11/19/25 | CYTK | Cytokinetics Inc | | Health | Drug | Pharmaceutical Preparations | Parshall B Lynne | CA | D | | S | -324 | 64.73 | 0 | -5 | -18 | 23 | D | | | | | | | | | | | | | | |
11/19/25 18:45 | 11/17/25 | ELVN | Enliven Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kintz Samuel | CO | DO | P,CEO | S | -273 | 21.82 | 0 | -13 | -1 | 890 | I | | | | | | | | | | | | | | |
11/19/25 18:28 | 11/12/25 | NATR | Natures Sunshine Products Inc | UT | Health | Drug | Pharmaceutical Preparations | Norman Daniel C | UT | O | EVP,P,As | S | -182 | 20.46 | 0 | -9 | -12 | 63 | D | | | | | | | | | | | | | | |
11/19/25 18:00 | 11/18/25 | ACAD | Acadia Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Schneyer Mark C. | CA | O | EVP,CFO | S.d | -243 | 23.69 | 0 | -10 | -16 | 53 | D | | | | | | | | | | | | | | |
11/19/25 18:00 | 11/18/25 | ACAD | Acadia Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Kihara James | CA | O | PRINCIPA | S.d | -97 | 23.69 | 0 | -4 | -14 | 25 | D | | | | | | | | | | | | | | |
11/19/25 17:24 | 11/18/25 | NATR | Natures Sunshine Products Inc | UT | Health | Drug | Pharmaceutical Preparations | Lanoy Jonathan David | UT | O | SVP,Chie | S | -102 | 20.45 | 0 | -5 | -10 | 46 | D | | | | | | | | | | | | | | |
11/19/25 17:14 | 11/17/25 | NUVL | Nuvalent, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Balcom Alexandra | MA | O | CFO | S.dm | -2,065 | 99.62 | 0 | -21 | -25 | 62 | D | | | | | | | | | | | | | | |
11/19/25 17:13 | 11/17/25 | NUVL | Nuvalent, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Miller Deborah Ann | MA | O | GC | S.d | -2,553 | 105.50 | 0 | -24 | -33 | 49 | D | | | | | | | | | | | | | | |
11/19/25 17:08 | 11/17/25 | BBIO | Bridgebio Pharma, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Lo Andrew | CA | D | | S.m | -6,320 | 66.11 | 0 | -96 | -60 | 65 | M | | | | | | | | | | | | | | |
11/19/25 17:06 | 11/17/25 | BBIO | Bridgebio Pharma, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Scott Randal W. | CA | D | | S.d | -666 | 66.65 | 0 | -10 | -39 | 16 | D | | | | | | | | | | | | | | |
11/19/25 16:57 | 11/17/25 | ONC | Beone Medicines Ltd. | | Health | Drug | Pharmaceutical Preparations | Wu Xiaobin | V8 | O | P,COO | S | -1,518 | 380.43 | 0 | -4 | 0 | 985 | D | | | | | | | | | | | | | | |
11/19/25 16:53 | 11/17/25 | RPRX | Royalty Pharma Plc | X0 | Health | Drug | Pharmaceutical Preparations | Coyne Terrance P. | NY | O | EVP,CFO | S | -2,735 | 39.30 | 0 | -70 | -8 | 829 | I | | | | | | | | | | | | | | |
11/19/25 16:47 | 11/17/25 | NUVB | Nuvation Bio Inc. | DE | Health | Drug | Pharmaceutical Preparations | Liu Dongfang | NY | O | CHIEF ME | S.dm | -148 | 4.93 | 0 | -30 | -63 | 18 | D | | | | | | | | | | | | | | |
11/19/25 16:39 | 11/17/25 | RCUS | Arcus Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Jaen Juan C. | CA | O | P | S.m | -1,013 | 20.26 | 0 | -50 | -3 | 1,404 | I | | | | | | | | | | | | | | |
11/19/25 16:38 | 11/17/25 | KNSA | Kiniksa Pharmaceuticals International, Plc | | Health | Drug | Pharmaceutical Preparations | Tessari Eben | X0 | O | COO | S.d | -514 | 41.24 | 0 | -12 | -35 | 23 | D | | | | | | | | | | | | | | |
11/19/25 16:32 | 11/17/25 | PCRX | Pacira Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Slonin Jonathan | CA | O | Chief Me | S | -95 | 24.09 | 0 | -4 | -2 | 178 | D | | | | | | | | | | | | | | |
11/19/25 16:21 | 11/17/25 | AMRX | Amneal Pharmaceuticals, Inc. | | Health | Drug | Pharmaceutical Preparations | Nark Ted C | NJ | D | | S | -586 | 11.72 | 0 | -50 | -15 | 291 | D | | | | | | | | | | | | | | |
11/19/25 16:13 | 11/18/25 | KALV | Kalvista Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Palleiko Benjamin L | MA | DO | CEO | S.d | -65 | 14.48 | 0 | -4 | -1 | 404 | D | | | | | | | | | | | | | | |
11/19/25 16:11 | 11/18/25 | KALV | Kalvista Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Yea Christopher | MA | O | CHIEF DE | S.d | -39 | 14.48 | 0 | -3 | -2 | 134 | D | | | | | | | | | | | | | | |
11/19/25 16:11 | 11/18/25 | KALV | Kalvista Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Audhya Paul K. | MA | O | CHIEF ME | S.d | -45 | 14.48 | 0 | -3 | -2 | 126 | D | | | | | | | | | | | | | | |