8/29/25 20:35 | 8/27/25 | CVKD | Cadrenal Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Szot Matthew K | FL | O | CFO | S.m | -28 | 14.00 | 0 | -2 | -6 | 31 | D | | | | | | | | | | | | | | |
8/29/25 20:34 | 8/27/25 | CVKD | Cadrenal Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Pham Quang X | FL | DOT | CEO,CB | S.m | -70 | 13.99 | 0 | -5 | -1 | 413 | D | | | | | | | | | | | | | | |
8/29/25 19:08 | 8/27/25 | AXSM | Axsome Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Jeffs Roger | NY | D | | S.m | -7,303 | 121.72 | 0 | -60 | -46 | 71 | D | | | | | | | | | | | | | | |
8/29/25 18:46 | 8/22/25 | CYRX | Cryoport, Inc. | NV | Health | Drug | Pharmaceutical Preparations | Hariri Robert J | TN | D | | S | -43 | 8.60 | 0 | -5 | -16 | 26 | D | | | | | | | | | | | | | | |
8/29/25 17:30 | 8/27/25 | PTGX | Protagonist Therapeutics, Inc | DE | Health | Drug | Pharmaceutical Preparations | Waddill William D. | CA | D | | S | -237 | 59.25 | 0 | -4 | -30 | 9 | D | | | | | | | | | | | | | | |
8/29/25 17:21 | 8/28/25 | XERS | Xeris Biopharma Holdings, Inc. | | Health | Drug | Pharmaceutical Preparations | Sherman Jeffrey W | IL | D | | S.d | -335 | 7.92 | 0 | -42 | -16 | 225 | D | | | | | | | | | | | | | | |
8/29/25 17:03 | 8/27/25 | ELVN | Enliven Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Hohl Benjamin | CO | O | CFO | S.d | -67 | 20.63 | 0 | -3 | -12 | 23 | D | | | | | | | | | | | | | | |
8/29/25 16:28 | 8/28/25 | RNA | Avidity Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Boyce Sarah | CA | DO | P,CEO | S.d | -1,235 | 49.39 | 0 | -25 | -8 | 306 | D | | | | | | | | | | | | | | |
8/29/25 16:19 | 8/27/25 | APLS | Apellis Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Francois Cedric | MA | DO | CEO | S.m | -6,353 | 28.23 | 0 | -225 | -12 | 1,646 | I | | | | | | | | | | | | | | |
8/29/25 16:09 | 8/27/25 | AGIO | Agios Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Scadden David | MA | D | | S.d | -8 | 40.00 | 0 | 0 | -1 | 18 | D | | | | | | | | | | | | | | |
8/29/25 16:05 | 8/27/25 | SUPN | Supernus Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Khattar Jack A. | MD | DO | P,CEO | S.dm | -1,569 | 45.10 | 0 | -35 | -2 | 2,098 | D | | | | | | | | | | | | | | |
8/29/25 16:05 | 8/27/25 | SUPN | Supernus Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Newhall Charles W III | MD | D | | S | -161 | 45.01 | 0 | -4 | -3 | 130 | D | | | | | | | | | | | | | | |
8/29/25 16:02 | 8/27/25 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Bhatia Sangeeta N. | MA | D | | S | -103 | 386.69 | 0 | 0 | -6 | 5 | D | | | | | | | | | | | | | | |
8/28/25 20:39 | 8/26/25 | BYSI | Beyondspring Inc. | | Health | Drug | Pharmaceutical Preparations | Decheng Capital China Life Sciences Usd Fund Iii, L.P. | CA | T | | S.m | -7 | 1.79 | 0 | -4 | 0 | 4,419 | I | | | | | | | | | | | | | | |
8/28/25 19:32 | 8/26/25 | QTTB | Q32 Bio Inc. | DE | Health | Drug | Pharmaceutical Preparations | Morrison Jodie Pope | MA | DO | CEO | S | -19 | 1.80 | 0 | -10 | -8 | 122 | D | | | | | | | | | | | | | | |
8/28/25 19:30 | 8/26/25 | ARDX | Ardelyx, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Williams Laura A | MA | O | Chief Pa | S.d | -490 | 6.12 | 0 | -80 | -18 | 366 | D | | | | | | | | | | | | | | |
8/28/25 19:29 | 8/21/25 | ARDX | Ardelyx, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kelliher Mike | MA | O | Chief Bu | S | -32 | 5.93 | 0 | -5 | -2 | 277 | D | | | | | | | | | | | | | | |
8/28/25 19:28 | 8/26/25 | QTTB | Q32 Bio Inc. | DE | Health | Drug | Pharmaceutical Preparations | Violette Shelia M. | MA | O | Chief Sc | S | -5 | 1.80 | 0 | -3 | -3 | 95 | D | | | | | | | | | | | | | | |
8/28/25 19:20 | 8/26/25 | QTTB | Q32 Bio Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kalowski Lee | MA | O | CFO,P | S | -8 | 1.80 | 0 | -4 | -8 | 49 | D | | | | | | | | | | | | | | |
8/28/25 17:40 | 8/26/25 | SION | Sionna Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Cloonan Michael | MA | DO | P,CEO | S.dm | -624 | 24.97 | 0 | -25 | -4 | 547 | D | | | | | | | | | | | | | | |
8/28/25 17:40 | 8/26/25 | SION | Sionna Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Ridloff Elena | MA | O | CFO,Head | S.m | -602 | 25.70 | 0 | -23 | -33 | 48 | D | | | | | | | | | | | | | | |
8/28/25 17:00 | 8/27/25 | CPRX | Catalyst Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Tierney David S | FL | D | | S.d | -525 | 20.20 | 0 | -26 | -6 | 380 | D | | | | | | | | | | | | | | |
8/28/25 17:00 | 8/26/25 | CPRX | Catalyst Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Miller Steve | FL | O | Chief Op | S.d | -2,332 | 20.28 | 0 | -115 | -10 | 1,060 | D | | | | | | | | | | | | | | |
8/28/25 17:00 | 8/26/25 | CPRX | Catalyst Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Daly Richard J | FL | DO | P,CEO | S.d | -474 | 20.62 | 0 | -23 | -9 | 227 | D | | | | | | | | | | | | | | |
8/28/25 16:55 | 8/26/25 | EWTX | Edgewise Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Russell Alan J | CO | DO | Chief Sc | S.d | -1,460 | 14.60 | 0 | -100 | -81 | 23 | D | | | | | | | | | | | | | | |
8/28/25 16:25 | 8/27/25 | AMRX | Amneal Pharmaceuticals, Inc. | | Health | Drug | Pharmaceutical Preparations | Kiely John | NJ | D | | S | -295 | 9.23 | 0 | -32 | -12 | 225 | D | | | | | | | | | | | | | | |
8/28/25 16:14 | 8/28/25 | LLY | Eli Lilly & Co | IN | Health | Drug | Pharmaceutical Preparations | Zakrowski Donald A | IN | O | SVP,Fina | S | -735 | 734.93 | 0 | -1 | -15 | 6 | D | | | | | | | | | | | | | | |
8/28/25 16:05 | 8/27/25 | TVTX | Travere Therapeutics, Inc. | CA | Health | Drug | Pharmaceutical Preparations | Cline Christopher R. | CA | O | CFO | S | -8 | 17.31 | 0 | 0 | -1 | 93 | D | | | | | | | | | | | | | | |
8/27/25 18:44 | 8/25/25 | OCUL | Ocular Therapeutix, Inc | DE | Health | Drug | Pharmaceutical Preparations | Kaiser Peter | MA | O | Chief De | S | -36 | 12.04 | 0 | -3 | -1 | 204 | D | | | | | | | | | | | | | | |
8/27/25 18:43 | 8/25/25 | OCUL | Ocular Therapeutix, Inc | DE | Health | Drug | Pharmaceutical Preparations | Nayak Sanjay | MA | O | Chief St | S | -23 | 12.04 | 0 | -2 | -1 | 280 | D | | | | | | | | | | | | | | |
8/27/25 18:42 | 8/25/25 | OCUL | Ocular Therapeutix, Inc | DE | Health | Drug | Pharmaceutical Preparations | Heier Jeffrey S. | MA | O | Chief Sc | S | -37 | 12.04 | 0 | -3 | -1 | 260 | D | | | | | | | | | | | | | | |
8/27/25 18:41 | 8/25/25 | OCUL | Ocular Therapeutix, Inc | DE | Health | Drug | Pharmaceutical Preparations | Dugel Pravin | MA | DO | See Rema | S | -259 | 12.04 | 0 | -21 | -1 | 3,478 | D | | | | | | | | | | | | | | |
8/27/25 17:16 | 8/25/25 | SER | Serina Therapeutics, Inc. | AL | Health | Drug | Pharmaceutical Preparations | Moreadith Randall | AL | O | Chief Sc | S.dm | -331 | 6.95 | 0 | -48 | -100 | 0 | D | | | | | | | | | | | | | | |
8/27/25 17:08 | 8/25/25 | NAMS | Newamsterdam Pharma Co N.V. | P7 | Health | Drug | Pharmaceutical Preparations | Kooij Louise Frederika | P7 | O | Chief Ac | S | -206 | 24.86 | 0 | -8 | -36 | 15 | D | | | | | | | | | | | | | | |
8/27/25 16:59 | 8/25/25 | SUPN | Supernus Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Mottola Frank | MD | O | SVP,Qual | S.d | -623 | 44.51 | 0 | -14 | -47 | 15 | D | | | | | | | | | | | | | | |
8/27/25 16:56 | 8/25/25 | SUPN | Supernus Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Newhall Charles W III | MD | D | | S | -45 | 45.00 | 0 | -1 | -1 | 133 | D | | | | | | | | | | | | | | |
8/27/25 16:56 | 8/25/25 | SUPN | Supernus Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Khattar Jack A. | MD | DO | P,CEO | S.d | -45 | 45.00 | 0 | -1 | 0 | 2,077 | D | | | | | | | | | | | | | | |
8/27/25 16:30 | 8/25/25 | NUVL | Nuvalent, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Noci Darlene | MA | O | Chief De | S.d | -298 | 74.62 | 0 | -4 | -8 | 48 | D | | | | | | | | | | | | | | |
8/26/25 21:40 | 8/22/25 | WVE | Wave Life Sciences Ltd. | U0 | Health | Drug | Pharmaceutical Preparations | Verdine Gregory L. | MA | D | | S | -100 | 10.00 | 0 | -10 | -3 | 285 | D | | | | | | | | | | | | | | |
8/26/25 21:40 | 8/22/25 | WVE | Wave Life Sciences Ltd. | U0 | Health | Drug | Pharmaceutical Preparations | Bolno Paul | MA | DO | P,CEO | S | -2,195 | 10.10 | 0 | -217 | -64 | 121 | D | | | | | | | | | | | | | | |
8/26/25 20:00 | 8/25/25 | KALV | Kalvista Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Sweeny Nicole | MA | O | Chief Co | S.d | -20 | 13.42 | 0 | -1 | -4 | 32 | D | | | | | | | | | | | | | | |
8/26/25 19:59 | 8/25/25 | KALV | Kalvista Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Yea Christopher | MA | O | Chief De | S.d | -26 | 13.42 | 0 | -2 | -1 | 132 | D | | | | | | | | | | | | | | |
8/26/25 19:57 | 8/25/25 | KALV | Kalvista Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Audhya Paul K. | MA | O | Chief Me | S.d | -31 | 13.42 | 0 | -2 | -2 | 123 | D | | | | | | | | | | | | | | |
8/26/25 19:00 | 8/22/25 | AXSM | Axsome Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Jeffs Roger | NY | D | | S.m | -4,405 | 120.05 | 0 | -37 | -22 | 131 | D | | | | | | | | | | | | | | |
8/26/25 18:56 | 8/22/25 | CORT | Corcept Therapeutics Inc | DE | Health | Drug | Pharmaceutical Preparations | Robb Gary Charles | CA | O | Chief Bu | S.d | -166 | 71.27 | 0 | -2 | -6 | 37 | D | | | | | | | | | | | | | | |
8/26/25 18:26 | 8/22/25 | EOLS | Evolus, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Yamagishi-Dressler Tomoko | CA | O | CMO | S | -43 | 7.51 | 0 | -6 | -6 | 90 | D | | | | | | | | | | | | | | |
8/26/25 18:19 | 8/25/25 | ANIP | Ani Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Leonard Matthew J | MN | D | | S | -229 | 90.62 | 0 | -3 | -27 | 7 | D | | | | | | | | | | | | | | |
8/26/25 18:01 | 8/22/25 | IRON | Disc Medicine, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Bitterman Kevin | MA | D | | S | -140 | 61.03 | 0 | -2 | 0 | 1,062 | I | | | | | | | | | | | | | | |
8/26/25 17:23 | 8/22/25 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Diaz Allene M. | CA | D | | S | -61 | 42.53 | 0 | -1 | -7 | 18 | D | | | | | | | | | | | | | | |
8/26/25 17:17 | 8/22/25 | ELTP | Elite Pharmaceuticals Inc /Nv/ | NJ | Health | Drug | Pharmaceutical Preparations | Elite Pharmaceuticals Inc /Nv/ | NJ | O | EVP Oper | S.d | -262 | 0.5243 | 0 | -500 | -10 | 4,300 | D | | | | | | | | | | | | | | |
8/26/25 16:30 | 8/22/25 | CRNX | Crinetics Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Pizzuti Dana | CA | O | Chief Me | S.d | -913 | 30.43 | 0 | -30 | -31 | 66 | D | | | | | | | | | | | | | | |
8/26/25 16:19 | 8/22/25 | SUPN | Supernus Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Newhall Charles W III | MD | D | | S | -64 | 45.00 | 0 | -1 | -1 | 134 | D | | | | | | | | | | | | | | |
8/26/25 16:18 | 8/22/25 | SUPN | Supernus Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Dec Timothy C | MD | O | Senior V | S | -524 | 44.49 | 0 | -12 | -90 | 1 | D | | | | | | | | | | | | | | |
8/26/25 16:15 | 8/22/25 | TNGX | Tango Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Third Rock Ventures Iv, L.P. | MA | T | | S | -2,115 | 7.00 | 0 | -302 | -2 | 15,457 | D | | | | | | | | | | | | | | |
8/26/25 16:08 | 8/22/25 | SUPN | Supernus Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Khattar Jack A. | MD | DO | P,CEO | S.d | -68 | 45.00 | 0 | -2 | 0 | 2,076 | D | | | | | | | | | | | | | | |
8/25/25 21:33 | 8/22/25 | KALV | Kalvista Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Sweeny Nicole | MA | O | Chief Co | S.d | -25 | 13.22 | 0 | -2 | -6 | 29 | D | | | | | | | | | | | | | | |
8/25/25 21:13 | 8/21/25 | ARDX | Ardelyx, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Williams Laura A | MA | O | Chief Pa | S | -37 | 5.93 | 0 | -6 | -2 | 396 | D | | | | | | | | | | | | | | |
8/25/25 21:12 | 8/21/25 | ARDX | Ardelyx, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Renz Justin A | MA | O | CFO | S | -42 | 5.93 | 0 | -7 | -2 | 409 | D | | | | | | | | | | | | | | |
8/25/25 21:08 | 8/21/25 | ARDX | Ardelyx, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Raab Michael | MA | DO | P,CEO | S | -271 | 5.93 | 0 | -46 | -3 | 1,528 | D | | | | | | | | | | | | | | |
8/25/25 21:03 | 8/21/25 | ARDX | Ardelyx, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Grammer Elizabeth A | MA | O | See Rema | S | -35 | 5.93 | 0 | -6 | -2 | 306 | D | | | | | | | | | | | | | | |
8/25/25 21:02 | 8/21/25 | ARDX | Ardelyx, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Foster Eric Duane | MA | O | Chief Co | S | -91 | 5.93 | 0 | -15 | -5 | 301 | D | | | | | | | | | | | | | | |
8/25/25 20:59 | 8/21/25 | RYTM | Rhythm Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Shulman Joseph | MA | O | Chief Te | S.d | -419 | 100.07 | 0 | -4 | -33 | 9 | D | | | | | | | | | | | | | | |
8/25/25 19:46 | 8/22/25 | KALV | Kalvista Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Yea Christopher | MA | O | Chief De | S.d | -31 | 13.22 | 0 | -2 | -2 | 131 | D | | | | | | | | | | | | | | |
8/25/25 19:46 | 8/21/25 | BYSI | Beyondspring Inc. | | Health | Drug | Pharmaceutical Preparations | Decheng Capital China Life Sciences Usd Fund Iii, L.P. | CA | T | | S.m | -10 | 1.77 | 0 | -6 | 0 | 4,423 | I | | | | | | | | | | | | | | |
8/25/25 19:46 | 8/22/25 | KALV | Kalvista Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Palleiko Benjamin L | MA | DO | CEO | S.d | -145 | 13.22 | 0 | -11 | -3 | 387 | D | | | | | | | | | | | | | | |
8/25/25 19:45 | 8/22/25 | KALV | Kalvista Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Audhya Paul K. | MA | O | Chief Me | S.d | -39 | 13.22 | 0 | -3 | -2 | 120 | D | | | | | | | | | | | | | | |
8/25/25 19:12 | 8/22/25 | JNJ | Johnson & Johnson | NJ | Health | Drug | Pharmaceutical Preparations | Duato Joaquin | NJ | DO | CEO,CB | S.d | -22,549 | 179.21 | 0 | -126 | -24 | 408 | D | | | | | | | | | | | | | | |
8/25/25 17:04 | 8/21/25 | NAMS | Newamsterdam Pharma Co N.V. | P7 | Health | Drug | Pharmaceutical Preparations | Kastelein Johannes Jacob Pieter | P7 | DO | Chief Sc | S.m | -2,472 | 24.72 | 0 | -100 | -59 | 69 | I | | | | | | | | | | | | | | |
8/25/25 16:27 | 8/22/25 | AMRX | Amneal Pharmaceuticals, Inc. | | Health | Drug | Pharmaceutical Preparations | Shah Nikita | NJ | O | EVP | S.m | -1,166 | 9.65 | 0 | -121 | -45 | 146 | D | | | | | | | | | | | | | | |
8/25/25 16:19 | 8/22/25 | ANIP | Ani Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Davis Krista | MN | O | SVP,CHRO | S | -161 | 91.10 | 0 | -2 | -3 | 63 | D | | | | | | | | | | | | | | |
8/22/25 21:00 | 8/20/25 | ROIV | Roivant Sciences Ltd. | D0 | Health | Drug | Pharmaceutical Preparations | Venker Eric | X0 | O | P,Immuno | S.d | -1,172 | 11.72 | 0 | -100 | -6 | 1,654 | D | | | | | | | | | | | | | | |
8/22/25 20:49 | 8/21/25 | DVAX | Dynavax Technologies Corp | DE | Health | Drug | Pharmaceutical Preparations | Deep Track Biotechnology Master Fund, Ltd. | E9 | T | | S.m | -22,352 | 10.82 | 0 | -2,065 | -12 | 15,726 | D | | | | | | | | | | | | | | |
8/22/25 19:07 | 8/21/25 | SKYE | Skye Bioscience, Inc. | NV | Health | Drug | Pharmaceutical Preparations | Schwab Andrew J. | CA | DT | | S.m | -801 | 3.46 | 0 | -231 | -2 | 9,682 | I | | | | | | | | | | | | | | |
8/22/25 19:05 | 8/21/25 | SKYE | Skye Bioscience, Inc. | NV | Health | Drug | Pharmaceutical Preparations | 5Am Partners Vii, LLC | CA | T | | S.m | -801 | 3.46 | 0 | -231 | -2 | 9,682 | I | | | | | | | | | | | | | | |
8/22/25 18:10 | 8/20/25 | ANIP | Ani Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Shanmugam Muthusamy | MN | DO | HEAD OF | S.m | -9,036 | 90.36 | 0 | -100 | -16 | 530 | I | | | | | | | | | | | | | | |
8/22/25 17:20 | 8/22/25 | RNA | Avidity Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Hughes Steven George | CA | O | Chief Me | S.d | -102 | 46.40 | 0 | -2 | -5 | 39 | D | | | | | | | | | | | | | | |
8/22/25 16:58 | 8/21/25 | BBIO | Bridgebio Pharma, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Trimarchi Thomas | CA | O | P,CFO | S | -2,090 | 49.48 | 0 | -42 | -9 | 421 | D | | | | | | | | | | | | | | |
8/22/25 16:46 | 8/20/25 | BBIO | Bridgebio Pharma, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kumar Neil | CA | DO | CEO | S | -1,277 | 48.82 | 0 | -26 | 0 | 5,857 | D | | | | | | | | | | | | | | |
8/22/25 16:38 | 8/20/25 | AMRX | Amneal Pharmaceuticals, Inc. | | Health | Drug | Pharmaceutical Preparations | Boyer Andrew S | NJ | O | EVP | S.d | -2,619 | 9.38 | 0 | -279 | -65 | 152 | D | | | | | | | | | | | | | | |
8/22/25 16:32 | 8/21/25 | UTHR | United Therapeutics Corp | DE | Health | Drug | Pharmaceutical Preparations | Mahon Paul A | MD | O | EVP,GC | S.d | -3,396 | 308.75 | 0 | -11 | -23 | 37 | D | | | | | | | | | | | | | | |
8/22/25 16:30 | 8/21/25 | SPRY | Ars Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Lowenthal Richard E | CA | DOT | P,CEO | S | -724 | 14.49 | 0 | -50 | 0 | 11,303 | I | | | | | | | | | | | | | | |
8/22/25 16:30 | 8/21/25 | SPRY | Ars Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Scott Kathleen D. | CA | O | CFO | S.d | -188 | 15.00 | 0 | -13 | -41 | 18 | D | | | | | | | | | | | | | | |
8/22/25 16:19 | 8/21/25 | BHC | Bausch Health Companies Inc. | NJ | Health | Drug | Pharmaceutical Preparations | Lee Frank D. | NJ | D | | S | -122 | 7.66 | 0 | -16 | -18 | 74 | D | | | | | | | | | | | | | | |
8/22/25 16:07 | 8/21/25 | LYEL | Lyell Immunopharma, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Seely Lynn | CA | DO | P,CEO | S | -77 | 10.54 | 0 | -7 | -10 | 68 | D | | | | | | | | | | | | | | |
8/22/25 16:06 | 8/21/25 | LYEL | Lyell Immunopharma, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Hill Stephen J. | CA | O | COO | S | -11 | 10.54 | 0 | -1 | -6 | 16 | D | | | | | | | | | | | | | | |
8/22/25 16:03 | 8/21/25 | LYEL | Lyell Immunopharma, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Newton Charles W. | CA | O | CFO | S | -15 | 10.54 | 0 | -1 | -5 | 25 | D | | | | | | | | | | | | | | |
8/22/25 16:02 | 8/21/25 | LYEL | Lyell Immunopharma, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Lee Gary K. | CA | O | Chief Sc | S | -15 | 10.54 | 0 | -1 | -9 | 16 | D | | | | | | | | | | | | | | |
8/21/25 21:32 | 8/19/25 | ARQT | Arcutis Biotherapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Burnett Patrick | CA | O | See Rema | S.m | -66 | 15.82 | 0 | -4 | -4 | 105 | D | | | | | | | | | | | | | | |
8/21/25 21:05 | 8/19/25 | NKTR | Nektar Therapeutics | DE | Health | Drug | Pharmaceutical Preparations | Zalevsky Jonathan | CA | O | Chief R, | S.d | -19 | 26.59 | 0 | -1 | -4 | 20 | D | | | | | | | | | | | | | | |
8/21/25 21:04 | 8/19/25 | NKTR | Nektar Therapeutics | DE | Health | Drug | Pharmaceutical Preparations | Wilson Mark Andrew | CA | O | GC | S.d | -18 | 26.59 | 0 | -1 | -3 | 20 | D | | | | | | | | | | | | | | |
8/21/25 21:03 | 8/19/25 | NKTR | Nektar Therapeutics | DE | Health | Drug | Pharmaceutical Preparations | Robin Howard W | CA | DO | P,CEO | S.d | -42 | 26.59 | 0 | -2 | -2 | 69 | D | | | | | | | | | | | | | | |
8/21/25 20:44 | 8/21/25 | CLNN | Clene Inc. | DE | Health | Drug | Pharmaceutical Preparations | General Resonance LLC | UT | T | | S | -18 | 5.34 | 0 | -3 | 0 | 705 | D | | | | | | | | | | | | | | |
8/21/25 18:48 | 8/20/25 | ELVN | Enliven Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kintz Samuel | CO | DO | P,CEO | S.a | -30 | 20.00 | 0 | -2 | 0 | 928 | I | | | | | | | | | | | | | | |
8/21/25 18:46 | 8/19/25 | ELVN | Enliven Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Lyssikatos Joseph P | CO | O | CHIEF SC | S.m | -248 | 19.86 | 0 | -13 | -1 | 940 | I | | | | | | | | | | | | | | |
8/21/25 17:44 | 8/21/25 | MDGL | Madrigal Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Sibold William John | PA | DO | P,CEO | S | -3,048 | 400.18 | 0 | -8 | -6 | 110 | D | | | | | | | | | | | | | | |
8/21/25 17:36 | 8/19/25 | SPRY | Ars Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Tanimoto Sarina | CA | OT | CHIEF ME | S.m | -704 | 14.08 | 0 | -50 | 0 | 11,353 | I | | | | | | | | | | | | | | |
8/21/25 17:07 | 8/20/25 | INSM | Insmed Inc | VA | Health | Drug | Pharmaceutical Preparations | Sharoky Melvin Md | NJ | D | | S | -1,295 | 129.50 | 0 | -10 | -3 | 307 | D | | | | | | | | | | | | | | |
8/21/25 17:05 | 8/19/25 | INSM | Insmed Inc | VA | Health | Drug | Pharmaceutical Preparations | Adsett Roger | NJ | O | COO | S | -3,190 | 127.58 | 0 | -25 | -19 | 106 | D | | | | | | | | | | | | | | |
8/21/25 17:00 | 8/19/25 | CYRX | Cryoport, Inc. | NV | Health | Drug | Pharmaceutical Preparations | Stefanovich Robert | TN | O | CFO | S.d | -81 | 8.67 | 0 | -9 | -4 | 207 | D | | | | | | | | | | | | | | |
8/21/25 16:30 | 8/19/25 | LQDA | Liquidia Corp | DE | Health | Drug | Pharmaceutical Preparations | Horobin Joanna | NC | D | | S | -136 | 27.17 | 0 | -5 | -13 | 34 | D | | | | | | | | | | | | | | |
8/21/25 16:30 | 8/20/25 | CRNX | Crinetics Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Pizzuti Dana | CA | O | Chief Me | S | -189 | 29.18 | 0 | -6 | -9 | 66 | D | | | | | | | | | | | | | | |
8/21/25 16:15 | 8/19/25 | TNGX | Tango Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Third Rock Ventures Iv, L.P. | MA | T | | S | -7,713 | 7.01 | 0 | -1,100 | -7 | 15,759 | D | | | | | | | | | | | | | | |
8/21/25 16:05 | 8/20/25 | SION | Sionna Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Cloonan Michael | MA | DO | P,CEO | S.d | -569 | 22.75 | 0 | -25 | -4 | 547 | D | | | | | | | | | | | | | | |
8/21/25 16:04 | 8/19/25 | SION | Sionna Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Ridloff Elena | MA | O | CFO,Head | S.m | -1,124 | 21.62 | 0 | -52 | -42 | 72 | D | | | | | | | | | | | | | | |
8/20/25 18:35 | 8/18/25 | BYSI | Beyondspring Inc. | | Health | Drug | Pharmaceutical Preparations | Decheng Capital China Life Sciences Usd Fund Iii, L.P. | CA | T | | S.m | -109 | 1.99 | 0 | -55 | -1 | 4,429 | I | | | | | | | | | | | | | | |
8/20/25 18:14 | 8/18/25 | IONS | Ionis Pharmaceuticals Inc | CA | Health | Drug | Pharmaceutical Preparations | Bennett C Frank | CA | O | EVP,Chie | S.d | -440 | 43.98 | 0 | -10 | -10 | 93 | D | | | | | | | | | | | | | | |
8/20/25 17:14 | 8/19/25 | ETON | Eton Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Gruber James R. | IL | O | CFO | S.m | -674 | 16.15 | 0 | -42 | -17 | 205 | D | | | | | | | | | | | | | | |
8/20/25 17:13 | 8/18/25 | SER | Serina Therapeutics, Inc. | AL | Health | Drug | Pharmaceutical Preparations | Moreadith Randall | AL | O | Chief Sc | S.dm | -22 | 5.18 | 0 | -4 | -100 | 0 | D | | | | | | | | | | | | | | |
8/20/25 17:00 | 8/18/25 | RCKT | Rocket Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Militello John | NJ | O | See Rema | S.m | -3 | 3.04 | 0 | -1 | -2 | 56 | D | | | | | | | | | | | | | | |
8/20/25 17:00 | 8/18/25 | RCKT | Rocket Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Schwartz Jonathan David | NJ | O | See Rema | S.m | -8 | 3.04 | 0 | -2 | -1 | 222 | D | | | | | | | | | | | | | | |
8/20/25 17:00 | 8/18/25 | RCKT | Rocket Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Wilson Martin | NJ | O | GC | S.m | -5 | 3.04 | 0 | -2 | -1 | 135 | D | | | | | | | | | | | | | | |
8/20/25 16:57 | 8/18/25 | COLL | Collegium Pharmaceutical, Inc | VA | Health | Drug | Pharmaceutical Preparations | Dreyer Scott | MA | O | EVP,Chie | S.d | -626 | 38.21 | 0 | -16 | -14 | 104 | D | | | | | | | | | | | | | | |
8/20/25 16:42 | 8/18/25 | ANIP | Ani Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Thoma Jeanne | MN | D | | S | -1,920 | 89.15 | 0 | -22 | -48 | 23 | D | | | | | | | | | | | | | | |
8/20/25 16:41 | 8/20/25 | ANIP | Ani Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Pera Antonio R | MN | D | | S | -486 | 89.73 | 0 | -5 | -15 | 30 | D | | | | | | | | | | | | | | |
8/20/25 16:36 | 8/18/25 | KNSA | Kiniksa Pharmaceuticals International, Plc | X0 | Health | Drug | Pharmaceutical Preparations | Tessari Eben | X0 | O | COO | S.d | -547 | 33.77 | 0 | -16 | -29 | 40 | D | | | | | | | | | | | | | | |
8/20/25 16:36 | 8/18/25 | ELVN | Enliven Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kintz Samuel | CO | DO | P,CEO | S.m | -220 | 20.02 | 0 | -11 | -1 | 929 | I | | | | | | | | | | | | | | |
8/20/25 16:28 | 8/18/25 | INSM | Insmed Inc | VA | Health | Drug | Pharmaceutical Preparations | Lewis William | NJ | DO | Chair,CE | S.d | -881 | 128.40 | 0 | -7 | -1 | 588 | I | | | | | | | | | | | | | | |
8/20/25 16:13 | 8/18/25 | STOK | Stoke Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Ticho Barry | MA | O | Chief Me | S | -51 | 18.24 | 0 | -3 | -10 | 24 | D | | | | | | | | | | | | | | |
8/20/25 16:12 | 8/18/25 | STOK | Stoke Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kaye Edward M. Md | MA | D | | S | -221 | 18.24 | 0 | -12 | -7 | 153 | D | | | | | | | | | | | | | | |
8/20/25 16:11 | 8/18/25 | STOK | Stoke Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Allan Jonathan | MA | O | GC,Corp | S | -31 | 18.24 | 0 | -2 | -7 | 24 | D | | | | | | | | | | | | | | |
8/19/25 20:00 | 8/15/25 | WVE | Wave Life Sciences Ltd. | U0 | Health | Drug | Pharmaceutical Preparations | Tan Aik Na | MA | D | | S.d | -194 | 9.25 | 0 | -21 | -34 | 40 | D | | | | | | | | | | | | | | |
8/19/25 19:40 | 8/18/25 | BBIO | Bridgebio Pharma, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Trimarchi Thomas | CA | O | P,CFO | S | -872 | 50.23 | 0 | -17 | -4 | 463 | D | | | | | | | | | | | | | | |
8/19/25 19:40 | 8/18/25 | DAWN | Day One Biopharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | York Charles N II | CA | O | COO,CFO | S.d | -28 | 6.77 | 0 | -4 | -1 | 278 | D | | | | | | | | | | | | | | |
8/19/25 19:38 | 8/18/25 | DAWN | Day One Biopharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Dubow Adam | CA | O | GC,Secre | S.d | -30 | 6.77 | 0 | -4 | -7 | 55 | D | | | | | | | | | | | | | | |
8/19/25 19:37 | 8/18/25 | DAWN | Day One Biopharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Bender Jeremy | CA | DO | CEO | S.d | -109 | 6.77 | 0 | -16 | -1 | 1,770 | D | | | | | | | | | | | | | | |
8/19/25 19:36 | 8/18/25 | DAWN | Day One Biopharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Merendino Lauren | CA | O | Chief Co | S.d | -25 | 6.77 | 0 | -4 | -8 | 42 | D | | | | | | | | | | | | | | |
8/19/25 18:00 | 8/18/25 | ACAD | Acadia Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Schneyer Mark C. | CA | O | EVP,CFO | S | -554 | 25.18 | 0 | -22 | -35 | 40 | D | | | | | | | | | | | | | | |
8/19/25 17:28 | 8/18/25 | ALNY | Alnylam Pharmaceuticals, Inc. | | Health | Drug | Pharmaceutical Preparations | Garg Pushkal | MA | O | EVP Chie | S.m | -1,300 | 455.89 | 0 | -3 | -12 | 21 | D | | | | | | | | | | | | | | |
8/19/25 17:28 | 8/18/25 | ALNY | Alnylam Pharmaceuticals, Inc. | | Health | Drug | Pharmaceutical Preparations | Tanguler Tolga | MA | O | EVP,Chie | S | -633 | 453.27 | 0 | -1 | -5 | 29 | D | | | | | | | | | | | | | | |
8/19/25 17:27 | 8/18/25 | ALNY | Alnylam Pharmaceuticals, Inc. | | Health | Drug | Pharmaceutical Preparations | Poulton Jeffrey V. | MA | O | EVP,CFO | S | -1,031 | 453.27 | 0 | -2 | -4 | 50 | D | | | | | | | | | | | | | | |
8/19/25 17:27 | 8/18/25 | ALNY | Alnylam Pharmaceuticals, Inc. | | Health | Drug | Pharmaceutical Preparations | Greenstreet Yvonne | MA | DO | CEO | S | -3,163 | 453.27 | 0 | -7 | -11 | 57 | D | | | | | | | | | | | | | | |
8/19/25 17:26 | 8/18/25 | ALNY | Alnylam Pharmaceuticals, Inc. | | Health | Drug | Pharmaceutical Preparations | Fitzgerald Kevin Joseph | MA | O | CSO,EVP, | S | -633 | 453.27 | 0 | -1 | -6 | 23 | D | | | | | | | | | | | | | | |
8/19/25 17:26 | 8/18/25 | ALNY | Alnylam Pharmaceuticals, Inc. | | Health | Drug | Pharmaceutical Preparations | Bonney Michael W | MA | D | | S.d | -5,063 | 450.00 | 0 | -11 | -35 | 21 | D | | | | | | | | | | | | | | |
8/19/25 17:10 | 8/15/25 | COLL | Collegium Pharmaceutical, Inc | VA | Health | Drug | Pharmaceutical Preparations | Santini Gino | MA | D | | S.d | -201 | 37.19 | 0 | -5 | -5 | 95 | D | | | | | | | | | | | | | | |
8/19/25 16:40 | 8/18/25 | APLS | Apellis Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Watson David O. | MA | O | GC | S | -139 | 27.80 | 0 | -5 | -2 | 204 | D | | | | | | | | | | | | | | |
8/19/25 16:40 | 8/18/25 | ZLAB | Zai Lab Ltd | E9 | Health | Drug | Pharmaceutical Preparations | Smiley Joshua L | MA | O | See Rema | S.d | -241 | 36.24 | 0 | -7 | -8 | 77 | D | | | | | | | | | | | | | | |
8/19/25 16:40 | 8/18/25 | ZLAB | Zai Lab Ltd | E9 | Health | Drug | Pharmaceutical Preparations | Edmondson Frazor Titus III | MA | O | GC | S.d | -68 | 36.24 | 0 | -2 | -4 | 42 | D | | | | | | | | | | | | | | |
8/19/25 16:37 | 8/19/25 | CYTK | Cytokinetics Inc | | Health | Drug | Pharmaceutical Preparations | Malik Fady Ibraham | CA | O | EVP Rese | S.d | -77 | 38.31 | 0 | -2 | -1 | 141 | D | | | | | | | | | | | | | | |
8/19/25 16:30 | 8/15/25 | NUVL | Nuvalent, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Porter James Richard | MA | DO | P,CEO | S.d | -2,036 | 75.42 | 0 | -27 | -10 | 249 | D | | | | | | | | | | | | | | |
8/19/25 16:30 | 8/15/25 | LQDA | Liquidia Corp | DE | Health | Drug | Pharmaceutical Preparations | Kaseta Michael | NC | O | CFO,COO | S | -524 | 26.18 | 0 | -20 | -5 | 356 | D | | | | | | | | | | | | | | |
8/19/25 16:27 | 8/18/25 | KALV | Kalvista Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Yea Christopher | MA | O | Chief De | S.d | -35 | 13.19 | 0 | -3 | -2 | 129 | D | | | | | | | | | | | | | | |
8/19/25 16:26 | 8/18/25 | KALV | Kalvista Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Audhya Paul K. | MA | O | Chief Me | S.d | -39 | 13.19 | 0 | -3 | -2 | 117 | D | | | | | | | | | | | | | | |
8/19/25 16:26 | 8/18/25 | KALV | Kalvista Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Palleiko Benjamin L | MA | DO | CEO | S.d | -58 | 13.19 | 0 | -4 | -1 | 375 | D | | | | | | | | | | | | | | |
8/19/25 16:15 | 8/15/25 | HRMY | Harmony Biosciences Holdings, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kapadia Sandip | PA | O | CFO | S | -787 | 36.50 | 0 | -22 | -100 | 0 | D | | | | | | | | | | | | | | |
8/19/25 16:12 | 8/15/25 | ALXO | Alx Oncology Holdings Inc | DE | Health | Drug | Pharmaceutical Preparations | Pinto Shelly | CA | O | SVP,Fina | S | 0 | 0.6404 | 0 | -1 | -1 | 89 | D | | | | | | | | | | | | | | |
8/19/25 16:09 | 8/15/25 | ALXO | Alx Oncology Holdings Inc | DE | Health | Drug | Pharmaceutical Preparations | Lettmann Jason | CA | DO | CEO | S | -2 | 0.6404 | 0 | -2 | -1 | 213 | D | | | | | | | | | | | | | | |
8/19/25 16:08 | 8/18/25 | MCRB | Seres Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Shaff Eric D. | MA | D | | S.d | -4 | 16.65 | 0 | 0 | -2 | 11 | D | | | | | | | | | | | | | | |
8/19/25 16:07 | 8/18/25 | MCRB | Seres Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Desrosier Thomas | MA | O | See Rema | S.d | -1 | 16.65 | 0 | 0 | -1 | 7 | D | | | | | | | | | | | | | | |
8/19/25 16:07 | 8/18/25 | MCRB | Seres Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Henn Matthew R | MA | O | See Rema | S.d | -1 | 16.65 | 0 | 0 | -2 | 5 | D | | | | | | | | | | | | | | |
8/19/25 16:06 | 8/18/25 | MCRB | Seres Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Young Teresa L. | MA | O | See Rema | S.d | -1 | 16.65 | 0 | 0 | -1 | 5 | D | | | | | | | | | | | | | | |
8/18/25 18:19 | 8/15/25 | JNJ | Johnson & Johnson | NJ | Health | Drug | Pharmaceutical Preparations | Wolk Joseph J | NJ | O | EVP,CFO | S.d | -2,976 | 176.91 | 0 | -17 | -17 | 85 | D | | | | | | | | | | | | | | |
8/18/25 17:33 | 8/18/25 | MDGL | Madrigal Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Kelley Shannon T | PA | O | GC | S | -480 | 367.81 | 0 | -1 | -12 | 9 | D | | | | | | | | | | | | | | |
8/18/25 17:23 | 8/18/25 | ANIP | Ani Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Leonard Matthew J | MN | D | | S | -612 | 88.17 | 0 | -7 | -42 | 9 | D | | | | | | | | | | | | | | |
8/18/25 17:14 | 8/15/25 | RAPP | Rapport Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Bredt David | MA | O | Chief Sc | S | -127 | 15.00 | 0 | -9 | -2 | 427 | D | | | | | | | | | | | | | | |
8/18/25 17:02 | 8/14/25 | SNDX | Syndax Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Podlesak Dennis | NY | D | | S.dm | -875 | 15.19 | 0 | -58 | -23 | 192 | D | | | | | | | | | | | | | | |
8/18/25 16:35 | 8/14/25 | RCKT | Rocket Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Schwartz Jonathan David | NJ | O | See Rema | S | -34 | 3.02 | 0 | -11 | -5 | 224 | D | | | | | | | | | | | | | | |
8/18/25 16:35 | 8/14/25 | RCKT | Rocket Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Militello John | NJ | O | See Rema | S | -21 | 3.02 | 0 | -7 | -11 | 57 | D | | | | | | | | | | | | | | |
8/18/25 16:35 | 8/14/25 | RCKT | Rocket Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Wilson Martin | NJ | O | GC | S | -37 | 3.02 | 0 | -12 | -8 | 137 | D | | | | | | | | | | | | | | |
8/18/25 16:34 | 8/15/25 | ANIP | Ani Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Walsh Patrick D | MN | D | | S | -801 | 89.05 | 0 | -9 | -11 | 70 | D | | | | | | | | | | | | | | |
8/18/25 16:33 | 8/15/25 | EBS | Emergent Biosolutions Inc. | DE | Health | Drug | Pharmaceutical Preparations | Zoon Kathryn C | MD | D | | S | -63 | 8.87 | 0 | -7 | -9 | 72 | D | | | | | | | | | | | | | | |
8/18/25 16:32 | 8/14/25 | ANIP | Ani Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Shanmugam Muthusamy | MN | DO | HEAD OF | S.m | -8,825 | 88.25 | 0 | -100 | -14 | 630 | I | | | | | | | | | | | | | | |
8/18/25 16:31 | 8/14/25 | SUPN | Supernus Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Sensenig Bethany | MD | D | | S | -227 | 42.25 | 0 | -5 | -100 | 0 | D | | | | | | | | | | | | | | |
8/18/25 16:29 | 8/15/25 | ZLAB | Zai Lab Ltd | E9 | Health | Drug | Pharmaceutical Preparations | Chen Yajing | MA | O | CFO | S.d | -51 | 35.42 | 0 | -1 | -8 | 17 | D | | | | | | | | | | | | | | |
8/18/25 16:29 | 8/15/25 | ANIP | Ani Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Gassert Chad | MN | O | SVP - CO | S | -1,739 | 86.97 | 0 | -20 | -7 | 247 | I | | | | | | | | | | | | | | |
8/18/25 16:28 | 8/14/25 | SUPN | Supernus Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Hudson Frederick M. | MD | D | | S | -315 | 42.26 | 0 | -7 | -14 | 46 | D | | | | | | | | | | | | | | |
8/18/25 16:19 | 8/14/25 | INSM | Insmed Inc | VA | Health | Drug | Pharmaceutical Preparations | Schaeffer Orlov S Nicole | NJ | O | Chief Pe | S | -1,273 | 127.34 | 0 | -10 | -11 | 80 | D | | | | | | | | | | | | | | |
8/15/25 19:23 | 8/13/25 | IRON | Disc Medicine, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Bitterman Kevin | MA | D | | S.m | -1,966 | 61.11 | 0 | -32 | -3 | 1,064 | I | | | | | | | | | | | | | | |
8/15/25 19:11 | 8/14/25 | BYSI | Beyondspring Inc. | | Health | Drug | Pharmaceutical Preparations | Decheng Capital China Life Sciences Usd Fund Iii, L.P. | CA | T | | S.m | -10 | 2.00 | 0 | -5 | 0 | 4,483 | I | | | | | | | | | | | | | | |
8/15/25 18:13 | 8/15/25 | CNTA | Centessa Pharmaceuticals Plc | X0 | Health | Drug | Pharmaceutical Preparations | Hussain Iqbal J | X0 | O | GC | S.d | -103 | 17.23 | 0 | -6 | -5 | 111 | D | | | | | | | | | | | | | | |
8/15/25 18:04 | 8/15/25 | MDGL | Madrigal Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Bate Kenneth | PA | D | | S.d | -3,652 | 365.20 | 0 | -10 | -79 | 3 | D | | | | | | | | | | | | | | |
8/15/25 17:59 | 8/13/25 | ARWR | Arrowhead Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Hamilton James C | CA | O | Chief Me | S.m | -200 | 20.00 | 0 | -10 | -4 | 262 | D | | | | | | | | | | | | | | |
8/15/25 17:50 | 8/15/25 | RNA | Avidity Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | McCarthy Teresa | CA | O | CHRO | S.d | -466 | 46.56 | 0 | -10 | -9 | 97 | D | | | | | | | | | | | | | | |
8/15/25 17:08 | 8/13/25 | COLL | Collegium Pharmaceutical, Inc | VA | Health | Drug | Pharmaceutical Preparations | Dreyer Scott | MA | O | EVP,Chie | S.d | -185 | 38.03 | 0 | -5 | -4 | 104 | D | | | | | | | | | | | | | | |
8/15/25 16:57 | 8/13/25 | XERS | Xeris Biopharma Holdings, Inc. | | Health | Drug | Pharmaceutical Preparations | Johnson John | IL | D | | S | -786 | 7.32 | 0 | -108 | -11 | 833 | D | | | | | | | | | | | | | | |
8/15/25 16:40 | 8/13/25 | ONC | Beone Medicines Ltd. | | Health | Drug | Pharmaceutical Preparations | Wu Xiaobin | V8 | O | P,COO | S.dm | -27,348 | 304.56 | 0 | -90 | -7 | 1,245 | D | | | | | | | | | | | | | | |
8/15/25 16:38 | 8/13/25 | ONC | Beone Medicines Ltd. | | Health | Drug | Pharmaceutical Preparations | Lee Chan Henry | V8 | O | SVP,GC | S.d | -3,309 | 300.45 | 0 | -11 | -4 | 252 | D | | | | | | | | | | | | | | |
8/15/25 16:31 | 8/14/25 | AMRX | Amneal Pharmaceuticals, Inc. | | Health | Drug | Pharmaceutical Preparations | Shah Nikita | NJ | O | EVP | S | -666 | 9.29 | 0 | -72 | -21 | 267 | D | | | | | | | | | | | | | | |
8/15/25 16:31 | 8/13/25 | STOK | Stoke Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Allan Jonathan | MA | O | GC,Corp | S | -206 | 15.00 | 0 | -14 | -41 | 20 | D | | | | | | | | | | | | | | |
8/15/25 16:30 | 8/14/25 | ABEO | Abeona Therapeutics Inc. | DE | Health | Drug | Pharmaceutical Preparations | Crombez Eric | OH | D | | S | -33 | 6.93 | 0 | -5 | -10 | 42 | D | | | | | | | | | | | | | | |
8/15/25 16:30 | 8/15/25 | ABEO | Abeona Therapeutics Inc. | DE | Health | Drug | Pharmaceutical Preparations | Vazzano Joseph Walter | OH | O | CFO | S | -110 | 7.36 | 0 | -15 | -3 | 463 | D | | | | | | | | | | | | | | |
8/15/25 16:30 | 8/13/25 | AMRX | Amneal Pharmaceuticals, Inc. | | Health | Drug | Pharmaceutical Preparations | Konidaris Tasos | NJ | O | EVP,CFO | S.m | -4,663 | 9.33 | 0 | -500 | -80 | 122 | D | | | | | | | | | | | | | | |
8/15/25 16:23 | 8/15/25 | CYTK | Cytokinetics Inc | | Health | Drug | Pharmaceutical Preparations | Blum Robert I | CA | DO | P,CEO | S | -192 | 38.42 | 0 | -5 | -1 | 387 | D | | | | | | | | | | | | | | |
8/15/25 16:12 | 8/13/25 | COLL | Collegium Pharmaceutical, Inc | VA | Health | Drug | Pharmaceutical Preparations | Rubric Capital Management LP | NY | T | | S | -946 | 37.85 | 0 | -25 | -1 | 3,133 | I | | | | | | | | | | | | | | |
8/15/25 16:09 | 8/6/25 | RNA | Avidity Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Maclean Michael F | CA | O | CFO | S | -1,321 | 42.73 | 0 | -31 | -32 | 66 | D | | | | | | | | | | | | | | |
8/15/25 16:07 | 8/13/25 | RNA | Avidity Biosciences, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Hughes Steven George | CA | O | Chief Me | S.d | -72 | 46.66 | 0 | -2 | -4 | 39 | D | | | | | | | | | | | | | | |
8/15/25 16:05 | 8/14/25 | ALNY | Alnylam Pharmaceuticals, Inc. | | Health | Drug | Pharmaceutical Preparations | Ausiello Dennis A | MA | D | | S.d | -13,730 | 436.58 | 0 | -31 | -88 | 4 | D | | | | | | | | | | | | | | |
8/15/25 12:45 | 8/13/25 | NATR | Natures Sunshine Products Inc | UT | Health | Drug | Pharmaceutical Preparations | Lanoy Jonathan David | UT | O | SVP,Chie | S | -83 | 16.51 | 0 | -5 | -9 | 50 | D | | | | | | | | | | | | | | |
8/15/25 12:12 | 8/13/25 | NATR | Natures Sunshine Products Inc | UT | Health | Drug | Pharmaceutical Preparations | Brower Nathan G | UT | O | EVP,GC | S | -165 | 16.54 | 0 | -10 | -17 | 48 | D | | | | | | | | | | | | | | |
8/14/25 19:43 | 8/12/25 | EWTX | Edgewise Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Moore John R | CO | O | GC | S.d | -28 | 13.39 | 0 | -2 | -17 | 10 | D | | | | | | | | | | | | | | |
8/14/25 19:43 | 8/12/25 | EWTX | Edgewise Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Derakhshan Behrad | CO | O | Chief Bu | S.d | -33 | 13.39 | 0 | -2 | -10 | 24 | D | | | | | | | | | | | | | | |
8/14/25 19:43 | 8/12/25 | EWTX | Edgewise Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Carruthers R Michael | CO | O | CFO | S.d | -19 | 13.39 | 0 | -1 | -2 | 86 | D | | | | | | | | | | | | | | |
8/14/25 19:42 | 8/12/25 | EWTX | Edgewise Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Russell Alan J | CO | DO | Chief Sc | S.d | -26 | 13.39 | 0 | -2 | -8 | 23 | D | | | | | | | | | | | | | | |
8/14/25 19:42 | 8/12/25 | EWTX | Edgewise Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Koch Kevin | CO | DO | P,CEO | S.d | -107 | 13.39 | 0 | -8 | -2 | 369 | D | | | | | | | | | | | | | | |
8/14/25 19:41 | 8/12/25 | EWTX | Edgewise Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Donovan Joanne M. | CO | O | CMO | S.d | -38 | 13.39 | 0 | -3 | -10 | 25 | D | | | | | | | | | | | | | | |
8/14/25 18:48 | 8/12/25 | RYTM | Rhythm Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Smith Hunter C | MA | O | CFO | S.dm | -2,705 | 96.29 | 0 | -28 | -19 | 117 | D | | | | | | | | | | | | | | |
8/14/25 18:47 | 8/12/25 | RYTM | Rhythm Pharmaceuticals, Inc. | DE | Health | Drug | Pharmaceutical Preparations | German Christopher Paul | MA | O | Corporat | S.d | -143 | 95.00 | 0 | -2 | -62 | 1 | D | | | | | | | | | | | | | | |
8/14/25 18:02 | 8/13/25 | MLYS | Mineralys Therapeutics, Inc. | DE | Health | Drug | Pharmaceutical Preparations | Rodman David Malcom | PA | O | Chief Me | S.d | -147 | 12.93 | 0 | -11 | -11 | 93 | D | | | | | | | | | | | | | | |
8/14/25 17:53 | 8/12/25 | ANIP | Ani Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Rowland Thomas Andrew | MN | O | SVP,HEAD | S | -426 | 85.71 | 0 | -5 | -11 | 41 | D | | | | | | | | | | | | | | |
8/14/25 17:48 | 8/12/25 | ANIP | Ani Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Lalwani Nikhil | MN | DO | P,CEO | S | -4,895 | 85.93 | 0 | -57 | -12 | 411 | D | | | | | | | | | | | | | | |
8/14/25 17:46 | 8/12/25 | ANIP | Ani Pharmaceuticals Inc | DE | Health | Drug | Pharmaceutical Preparations | Gutwerg Ori | MN | O | SVP,GENE | S | -508 | 86.53 | 0 | -6 | -7 | 84 | D | | | | | | | | | | | | | | |