Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	Title	T	TVal	Price	Qty	oc	Own	H
6/30/25 17:51	6/26/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Valantine Hannah	CA	D		S	-207	44.05	-5	-37	8	M
6/30/25 17:02	6/26/25	ZVRA	Zevra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Thompson Rahsaan	FL	OH	Chief Le	S	-221	9.21	-24	-36	43	D
6/27/25 17:07	6/26/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Noci Darlene	MA	O	Chief De	S.d	-315	78.71	-4	-8	48	D
6/27/25 17:05	6/25/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pelish Henry E.	MA	O	Chief Sc	S.dm	-863	79.88	-11	-15	63	D
6/27/25 16:39	6/26/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	S.d	-3,143	285.70	-11	-23	37	D
6/27/25 16:27	6/27/25	NATR	Natures Sunshine Products Inc	UT	Health	Drug	Pharmaceutical Preparations	Shanghai Fosun Pharmaceutical (Group) Co., Ltd.	F4	T		S	-32,714	11.46	-2,855	-98	64	I
6/27/25 16:15	6/26/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Edmondson Frazor Titus III	MA	O	GC	S.d	-212	36.13	-6	-13	39	D
6/27/25 16:15	6/25/25	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	Lee Ting-Chuan	CA	D		S	-1	0.5100	-3	0	1,429	D
6/27/25 16:15	6/25/25	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	Tsai Chun-Jung	CA	D		S.m	-9	0.5023	-17	-1	1,385	D
6/27/25 16:15	6/26/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Du Ying	MA	DO	Chairper	S.d	-855	36.13	-24	-4	515	D
6/27/25 16:15	6/26/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Chen Yajing	MA	O	CFO	S.d	-97	36.13	-3	-11	21	D
6/26/25 20:00	6/24/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Shelton Jerrell	TN	DO	P,CEO	S.d	-115	7.06	-16	-2	937	D
6/26/25 20:00	6/24/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kharabi Darius	MA	O	CHIEF BU	S	-18	4.01	-5	-7	63	D
6/26/25 20:00	6/24/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Mandalam Ramkumar	TN	D		S.d	-93	7.02	-13	-15	73	D
6/26/25 20:00	6/24/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Reumuth Mary	MA	O	CFO	S	-15	4.01	-4	-6	62	D
6/26/25 20:00	6/24/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bazemore Todd	MA	O	SEE REMA	S	-16	4.01	-4	-5	84	D
6/26/25 20:00	6/24/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Brazzell Romulus K	MA	O	SEE REMA	S	-21	4.01	-5	-6	83	D
6/26/25 20:00	6/24/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Iwicki Mark T	MA	D		S	-53	4.01	-13	-5	258	D
6/26/25 17:26	6/24/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Burns James William	MA	O	GC	S.d	-94	33.54	-3	-9	29	D
6/26/25 17:25	6/24/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gheuens Sarah	MA	O	Chief Me	S.d	-98	33.54	-3	-5	57	D
6/26/25 17:24	6/24/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jones Cecilia	MA	O	CFO	S.d	-60	33.54	-2	-6	30	D
6/26/25 17:23	6/24/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Milanova Tsveta	MA	O	Chief Co	S.d	-93	33.54	-3	-10	26	D
6/26/25 17:22	6/24/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Goff Brian	MA	DO	CEO	S.d	-627	33.54	-19	-14	112	D
6/26/25 17:08	6/24/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McCormick Frank	CA	D		S	-4,423	44.23	-100	-9	963	I
6/25/25 19:44	6/25/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Weinhoff Gregory M	X0	O	Chief Bu	S.d	-139	13.86	-10	-8	122	D
6/25/25 19:43	6/24/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Hussain Iqbal J	X0	O	GC	S.d	-168	14.02	-12	-10	111	D
6/25/25 19:42	6/24/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Accardi Mario Alberto	X0	O	P,Orexin	S.d	-210	14.00	-15	-6	216	D
6/25/25 18:52	6/23/25	OKUR	Onkure Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Saccomano Nicholas A	CO	DO	P,CEO	S	0	2.38	0	-2	4	D
6/25/25 18:49	6/23/25	OKUR	Onkure Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Leverone Jason A.	CO	O	CFO	S	-1	2.38	0	-2	13	D
6/25/25 17:09	6/23/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Wang Lai	V8	O	Global H	S	-267	260.00	-1	0	1,755	D
6/25/25 17:08	6/23/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Wu Xiaobin	V8	O	P,COO	S	-354	260.00	-1	0	1,245	D
6/25/25 17:08	6/24/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Wang Xiaodong	V8	DH	Chair, S	S	-533	265.50	-2	0	10,133	D
6/25/25 17:06	6/23/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Oyler John	V8	DO	CEO	S	-830	261.61	-3	0	54,229	D
6/25/25 17:01	6/23/25	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	Taiwan Carbon Nano Technology Corp	F5	T		S	0	0.00	-29	-1	5,471	D
6/25/25 16:38	6/24/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mesa Nilda	MD	D		S	-187	289.99	-1	-12	5	D
6/25/25 16:36	6/24/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Giltner Richard	MD	D		S.d	-879	289.60	-3	-14	19	D
6/25/25 16:18	6/23/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Bonstein Sara	NJ	O	CFO	S.d	-5,879	101.78	-58	-38	94	D
6/24/25 21:01	6/20/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Venker Eric	X0	O	P,COO	S.d	-1,145	11.45	-100	-6	1,462	D
6/24/25 20:29	6/23/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Reardon Andrew	FL	O	CLO,Secr	S	-57	114.08	-1	-2	32	D
6/24/25 18:33	6/23/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Piscitelli Dominic	CA	O	CFO	S.m	-351	10.49	-34	-33	68	D
6/24/25 18:08	6/20/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Springhorn Jeremy P.	P7	D		S	-31	14.45	-2	-5	38	D
6/24/25 18:03	6/20/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Post Leonard E	P7	D		S	-31	14.45	-2	-7	30	D
6/24/25 17:53	6/20/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Kaye Jack	P7	D		S	-31	14.45	-2	-9	20	D
6/24/25 17:50	6/20/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Jacques Rachelle Suzanne	P7	D		S	-31	14.45	-2	-7	28	D
6/24/25 17:45	6/20/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Gut Robert	P7	D		S	-48	14.45	-3	-6	57	D
6/24/25 17:42	6/20/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Balachandran Madhavan	P7	D		S	-31	14.45	-2	-5	38	D
6/24/25 17:36	6/20/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lyssikatos Joseph P	CO	O	CHIEF SC	S	-267	21.40	-13	-1	965	I
6/24/25 17:34	6/20/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Meek David D.	P7	D		S	-31	14.45	-2	-6	34	D
6/24/25 16:39	6/20/25	VSTM	Verastem, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Paterson Dan	MA	DO	P,CEO	S	-91	5.13	-18	-4	444	D
6/24/25 16:37	6/20/25	VSTM	Verastem, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Calkins Daniel	MA	O	CFO	S.m	-21	5.13	-4	-4	110	D
6/24/25 16:08	6/24/25	ARVN	Arvinas, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Saik Andrew	CT	O	CFO	S	-43	7.61	-6	-3	164	D
6/24/25 16:00	6/20/25	MRUS	Merus N.V.	P7	Health	Drug	Pharmaceutical Preparations	Silverman Peter B.	P7	O	COO,GC	S.d	-1,794	52.76	-34	-100	0	D
6/23/25 19:44	6/18/25	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	Tsai Chun-Jung	CA	D		S.m	-14	0.5260	-26	-2	1,402	D
6/23/25 19:42	6/20/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Murdock Hunter R.	NY	O	GC	S.dm	-1,371	101.42	-14	-100	0	D
6/23/25 16:10	6/20/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Lis William	MA	D		S	-493	35.67	-14	-28	35	D
6/23/25 13:50	6/20/25	RARE	Ultragenyx Pharmaceutical Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sanders Corazon (Corsee) D.	CA	D		S	-90	37.39	-2	-14	15	D
6/23/25 11:35	6/18/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Ramaswamy Vivek	DC	T		S.m	-13,085	11.46	-1,142	-2	50,642	D
6/20/25 21:09	6/18/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cheng Andrew	CA	DO	P,CEO	S	-363	54.84	-7	-1	550	D
6/20/25 21:08	6/18/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gangloff Scott A.	CA	O	CTO	S	-47	54.84	-1	-3	23	D
6/20/25 21:08	6/20/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lamy Patrick	CA	O	SVP,Comm	S	-48	54.59	-1	-3	32	D
6/20/25 21:07	6/18/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rolph Timothy	CA	O	Chief Sc	S	-62	54.84	-1	-1	166	D
6/20/25 21:07	6/18/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	White William Richard	CA	O	CFO	S	-90	54.84	-2	-3	58	D
6/20/25 21:07	6/18/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yale Catriona	CA	O	Chief De	S	-90	54.84	-2	-2	91	D
6/20/25 21:06	6/18/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Young Jonathan	CA	O	COO	S	-80	54.84	-1	-1	257	D
6/20/25 20:58	6/20/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Saha Saurabh	X0	DO	CEO	S.d	-695	12.63	-55	-18	259	D
6/20/25 20:24	6/16/25	IGMS	Igm Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Weber Steven	CA	O	Principa	S	-1	1.20	0	-2	27	D
6/20/25 20:23	6/16/25	IGMS	Igm Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tahir Misbah	CA	O	CFO	S	-2	1.20	-2	-1	179	D
6/20/25 20:20	6/16/25	IGMS	Igm Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Harler Mary Beth	CA	DO	CEO	S	-2	1.20	-2	0	338	D
6/20/25 20:19	6/16/25	IGMS	Igm Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Decker Lisa Lynn	CA	O	Chief Bu	S	-1	1.20	-1	-1	73	D
6/20/25 20:15	6/17/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Shelton Jerrell	TN	DO	P,CEO	S.dm	-2,290	6.74	-340	-27	912	D
6/20/25 19:43	6/16/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Potts Jeannette		O	GC	S	-71	15.14	-5	-4	115	D
6/20/25 18:38	6/18/25	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Karas Eric	CA	O	Chief Co	S.d	-240	16.00	-15	-66	8	D
6/20/25 17:42	6/17/25	TYRA	Tyra Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kaplan Gilla	CA	D		S.m	-94	9.78	-10	-25	28	D
6/20/25 16:32	6/18/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Welgus Howard G.	CA	D		S	-136	13.37	-10	-8	109	D
6/20/25 16:20	6/20/25	CLYM	Climb Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pimblett Emily	MA	O	SVP,Fina	S.d	-2	1.24	-1	-6	19	D
6/20/25 16:08	6/18/25	NKTX	Nkarta, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hastings Paul J	CA	DO	CEO	S	-3	1.79	-2	-1	320	D
6/20/25 16:07	6/18/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Fenton Dennis M	CA	D		S	-72	23.97	-3	-38	5	D
6/20/25 16:06	6/18/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Renton Hollings	CA	D		S	-72	23.97	-3	-38	5	D
6/20/25 11:22	6/16/25	VSTM	Verastem, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Paterson Dan	MA	DO	P,CEO	S	-2	5.65	0	0	462	D
6/20/25 11:22	6/16/25	VSTM	Verastem, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gagnon Robert E.	MA	D		S	-2	5.65	0	-1	42	D
6/20/25 11:21	6/16/25	VSTM	Verastem, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Stuglik Brian M	MA	D		S	-3	5.65	-1	-1	102	D
6/20/25 09:22	6/16/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yale Catriona	CA	O	Chief De	S.d	-542	54.23	-10	-10	92	D
6/20/25 09:22	6/16/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lamy Patrick	CA	O	SVP,Comm	S.d	-108	54.14	-2	-6	33	D
6/18/25 21:16	6/16/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Murdock Hunter R.	NY	O	GC	S.dm	-2,277	101.19	-23	-100	0	D
6/18/25 18:45	6/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Looker Benjamin	MI	O	GC	S	-7	1.15	-6	-2	401	D
6/18/25 18:44	6/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Koenig Sheldon L.	MI	DO	P,CEO	S	-34	1.11	-30	-2	1,541	D
6/18/25 18:44	6/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Halladay Benjamin	MI	O	CFO	S	-8	1.15	-7	-2	474	D
6/18/25 18:26	6/16/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Robb Gary Charles	CA	O	Chief Bu	S	-225	70.77	-3	-8	37	D
6/18/25 18:22	6/17/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kintz Samuel	CO	DO	P,CEO	S	-277	22.18	-13	-1	953	I
6/18/25 18:04	6/17/25	ARVN	Arvinas, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cacace Angela M	CT	O	Chief Sc	S	-19	7.49	-3	-2	154	D
6/18/25 18:02	6/17/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gallagher Kathleen P.	CA	O	Chief Pr	S	-28	30.24	-1	-2	50	D
6/18/25 17:18	6/16/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Franchi Jean M.	MA	O	CFO	S	-105	52.26	-2	-3	68	D
6/18/25 17:12	6/16/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Meisner Lara	MA	O	GC	S.d	-165	10.43	-16	-100	0	D
6/18/25 17:12	6/16/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Lee Chan Henry	V8	O	SVP,GC	S	-112	266.50	0	0	278	D
6/18/25 17:10	6/16/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Wang Lai	V8	O	Global H	S.m	-432	262.11	-2	0	1,769	D
6/18/25 17:08	6/16/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Wu Xiaobin	V8	O	P,COO	S.m	-568	261.27	-2	0	1,262	D
6/18/25 17:06	6/16/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Oyler John	V8	DO	CEO	S.m	-1,354	263.33	-5	0	54,270	D
6/18/25 16:50	6/16/25	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	Kling Douglas F	P7	O	COO	S.d	-1,929	19.29	-100	-69	44	D
6/18/25 16:39	6/16/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Tessari Eben	X0	O	COO	S.d	-489	28.28	-17	-22	62	D
6/18/25 16:31	6/16/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Fisher Andrew	X0	O	GC	S.d	-922	11.53	-80	-18	360	D
6/18/25 16:16	6/16/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Lewis William	NJ	DO	Chair,CE	S.d	-13,554	100.39	-135	-19	588	M
6/18/25 16:15	6/16/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Adsett Roger	NJ	O	COO	S	-1,056	98.82	-11	-8	131	D
6/18/25 16:15	6/16/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bredt David	MA	O	Chief Sc	S	-94	11.00	-9	-2	444	D
6/18/25 16:11	6/16/25	AMRX	Amneal Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Patel Gautam	NJ	D		S	-761	8.02	-95	-6	1,609	D
6/18/25 08:49	6/16/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Watson David O.	MA	O	GC	S	-94	18.77	-5	-2	214	D
6/17/25 19:55	6/13/25	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Wilson Troy Edward	CA	D		S	-37	3.40	-11	-20	44	D
6/17/25 19:52	6/13/25	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Stuglik Brian M	CA	D		S	-27	3.39	-8	-8	95	D
6/17/25 19:49	6/13/25	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Senderowicz Adrian	CA	D		S	-92	3.40	-27	-50	27	D
6/17/25 19:46	6/13/25	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Moyes Jay M	CA	D		S	-75	3.40	-22	-29	53	D
6/17/25 19:43	6/13/25	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dorval Allison	CA	D		S	-39	3.40	-12	-13	75	D
6/17/25 19:41	6/13/25	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cesano Alessandra	CA	D		S	-41	3.40	-12	-15	69	D
6/17/25 16:31	6/16/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Porter James Richard	MA	DO	P,CEO	S.d	-2,077	76.93	-27	-10	249	D
6/17/25 16:27	6/17/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Malik Fady Ibraham	CA	O	EVP Rese	S.d	-66	32.91	-2	-1	141	D
6/17/25 16:24	6/13/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hohl Benjamin	CO	O	CFO	S.d	-68	22.55	-3	-12	23	D
6/17/25 16:11	6/13/25	CTMX	Cytomx Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ogden Christopher	CA	O	CFO	S.dm	-33	2.72	-12	-5	226	D
6/17/25 16:10	6/16/25	CTMX	Cytomx Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Belvin Marcia	CA	O	SVP,Chie	S.d	-37	2.69	-14	-5	272	D
6/17/25 16:09	6/16/25	CTMX	Cytomx Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McCarthy Sean A.	CA	DO	CEO	S.d	-149	2.69	-56	-4	1,183	D
6/16/25 21:10	6/13/25	VNDA	Vanda Pharmaceuticals Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mitchell Stephen Ray	DC	D		S	-32	4.59	-7	-7	97	D
6/16/25 19:35	6/16/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	Montgomery Alan Bruce	CA	D		S.d	-20	9.22	-2	-10	21	D
6/16/25 19:31	6/16/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	Gustafson Kurt A	CA	D		S.d	-28	9.22	-3	-13	20	D
6/16/25 19:30	6/16/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	Gorman Kevin Charles	CA	D		S.d	-29	9.22	-3	-14	19	D
6/16/25 19:26	6/16/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	Feigal Ellen	CA	D		S.d	-28	9.22	-3	-13	19	D
6/16/25 19:22	6/16/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	Ranieri Richard J	CA	D		S.d	-28	9.22	-3	-13	19	D
6/16/25 19:05	6/12/25	TYRA	Tyra Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kaplan Gilla	CA	D		S.m	-535	10.32	-52	-58	38	D
6/16/25 17:47	6/13/25	TGTX	Tg Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Echelard Yann	NC	D		S	-369	36.94	-10	-4	229	D
6/16/25 17:24	6/13/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Cook Meredith	MN	O	SVP,GC,S	S	-25	61.37	0	-1	79	D
6/16/25 17:19	6/16/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Blum Robert I	CA	DO	P,CEO	S	-169	33.80	-5	-1	407	D
6/16/25 16:56	6/12/25	ETON	Eton Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Krempa David	IL	O	Chief Bu	S.m	-504	14.83	-34	-5	613	D
6/16/25 16:48	6/12/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Betz Stephen F.	CA	O	Chief Sc	S.d	-3,142	32.23	-97	-49	100	D
6/16/25 16:42	6/13/25	EOLS	Evolus, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Moatazedi David	CA	DO	See Rema	S.m	-1,283	10.03	-128	-26	365	D
6/16/25 16:03	6/12/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	Kalif Eliyahu Sharon	L3	O	EVP,CFO	S	-952	17.08	-56	-12	403	D
6/16/25 16:03	6/13/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rodman David Malcom	PA	O	Chief Me	S.d	-166	14.60	-11	-10	102	D
6/16/25 15:40	5/28/25	ANTX	An2 Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Leonard Braden Michael	IN	T		S	-218	1.09	-200	-6	3,017	I
6/16/25 08:48	6/12/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	S.d	-3,080	279.96	-11	-23	37	D
6/13/25 20:00	6/13/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	Verdine Gregory L.	MA	D		S	-209	6.95	-30	-10	283	D
6/13/25 19:57	6/13/25	LTRN	Lantern Pharma Inc.	TX	Health	Drug	Pharmaceutical Preparations	Fletcher Aaron G.L.	TX	T		S	-124	3.09	-40	-4	1,076	I
6/13/25 19:50	6/13/25	LTRN	Lantern Pharma Inc.	TX	Health	Drug	Pharmaceutical Preparations	Kreis Leslie W.	TX	T		S	-124	3.09	-40	-4	1,076	I
6/13/25 19:38	6/12/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Piscitelli Dominic	CA	O	CFO	S	-3	10.00	0	0	102	D
6/13/25 19:00	6/11/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Mandalam Ramkumar	TN	D		S.m	-75	7.03	-11	-14	66	D
6/13/25 16:31	6/11/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Hahn Mark W	X0	O	CFO	S	-4,560	11.40	-400	-3	12,279	D
6/13/25 16:30	6/11/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Zaccardelli David	X0	DO	P,CEO	S	-4,561	11.40	-400	-3	13,190	D
6/13/25 16:18	6/11/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fairey William	CA	D		S	-155	48.42	-3	-56	3	D
6/13/25 06:06	6/10/25	LTRN	Lantern Pharma Inc.	TX	Health	Drug	Pharmaceutical Preparations	Fletcher Aaron G.L.	TX	T		S.m	-208	3.38	-62	-5	1,116	I
6/13/25 06:01	6/10/25	LTRN	Lantern Pharma Inc.	TX	Health	Drug	Pharmaceutical Preparations	Kreis Leslie W.	TX	T		S.m	-208	3.38	-62	-5	1,116	I
6/12/25 20:42	6/10/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Swisher Daniel N Jr	CA	D		S.d	-155	70.61	-2	-100	0	D
6/12/25 20:41	6/10/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Guyer William	CA	O	Chief De	S.d	-1,448	72.42	-20	-78	5	D
6/12/25 18:34	6/10/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cheng Andrew	CA	DO	P,CEO	S	-2,045	54.05	-38	-6	556	D
6/12/25 18:33	6/10/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rolph Timothy	CA	O	Chief Sc	S	-127	54.00	-2	-1	167	D
6/12/25 18:33	6/10/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	White William Richard	CA	O	CFO	S	-151	54.00	-3	-5	59	D
6/12/25 18:33	6/10/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yale Catriona	CA	O	Chief De	S	-151	54.00	-3	-3	92	D
6/12/25 18:32	6/10/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lamy Patrick	CA	O	SVP,Comm	S	-50	54.00	-1	-3	33	D
6/12/25 18:32	6/10/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Young Jonathan	CA	O	COO	S	-135	53.99	-2	-1	258	D
6/12/25 18:18	6/11/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Flanagan W. Michael	CA	O	Chief Sc	S.d	-658	32.88	-20	-20	80	D
6/12/25 17:51	6/10/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Reardon Andrew	FL	O	CLO,Secr	S	-57	114.54	-1	-2	32	D
6/12/25 17:51	6/11/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Ball Titus B.	V8	O	Principa	S	-35	258.36	0	0	74	D
6/12/25 17:39	6/10/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Wang Xiaodong	V8	DH	Chair, S	S.d	-10,975	262.82	-42	0	10,159	D
6/12/25 17:00	6/10/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sundaram Preethi	FL	O	Chief St	S.m	-104	26.41	-4	-9	41	D
6/12/25 16:50	6/10/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	German Christopher Paul	MA	O	Corporat	S.d	-139	67.19	-2	-52	2	D
6/12/25 16:21	6/10/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Flammer Martina M.D.	NJ	O	Chief Me	S.dm	-4,117	91.16	-45	-35	83	D
6/12/25 16:20	6/10/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Schaeffer Orlov S Nicole	NJ	O	Chief Pe	S.dm	-12,659	92.09	-137	-61	89	D
6/12/25 16:19	6/10/25	AMRX	Amneal Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Patel Gautam	NJ	D		S	-453	8.02	-56	-3	1,704	D
6/12/25 16:19	6/10/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Bonstein Sara	NJ	O	CFO	S.d	-5,148	89.12	-58	-36	103	D
6/11/25 18:37	6/10/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Piscitelli Dominic	CA	O	CFO	S.m	-33	10.01	-3	-3	102	D
6/11/25 18:25	6/9/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Patel Anish	CO	O	COO	S	-136	20.34	-7	-2	303	I
6/11/25 17:40	6/9/25	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	Molina Arturo Md	CA	O	Chief Me	S.dm	-1,125	56.27	-20	-19	84	D
6/11/25 17:35	6/9/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Quart Barry D	X0	D		S.dm	-833	30.35	-27	-69	13	D
6/11/25 17:32	6/9/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Tessari Eben	X0	O	COO	S.dm	-2,160	30.48	-71	-49	72	D
6/11/25 17:13	6/9/25	AKBA	Akebia Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Malabre Richard C	MA	O	SVP,Chie	S.d	-60	4.01	-15	-5	267	D
6/11/25 17:04	6/9/25	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	Freund John Gordon	MA	D		S.d	-202	30.62	-7	-5	114	D
6/11/25 17:00	6/10/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Valantine Hannah	CA	D		S.d	-172	40.00	-4	-45	5	D
6/11/25 16:15	6/9/25	HROW	Harrow, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T		S.m	-924	30.59	-30	-1	3,905	I
6/11/25 09:14	6/9/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Schoenberg Mark	NJ	O	Chief Me	S.d	-38	7.37	-5	-3	153	D
6/10/25 20:07	6/10/25	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	Binder Steven B.	CT	D		S	-256	4.00	-64	-6	925	D
6/10/25 19:28	6/10/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Zecchini Edward J	TN	O	Chief Di	S.d	-353	6.85	-52	-36	90	D
6/10/25 19:25	6/9/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Mandalam Ramkumar	TN	D		S.d	-40	7.06	-6	-7	77	D
6/10/25 19:00	6/9/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jacobson Mark L.	NY	O	COO	S.d	-2,761	110.44	-25	-81	6	D
6/10/25 17:00	6/9/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Palleiko Benjamin L	MA	DO	CEO	S.d	-104	14.50	-7	-2	315	D
6/10/25 17:00	6/6/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McEnany Patrick J	FL	DH	Chairman	S.m	-5,217	26.09	-200	-4	4,282	D
6/10/25 16:57	6/6/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Lee Chan Henry	V8	O	SVP,GC	S	-179	256.11	-1	0	237	D
6/10/25 16:56	6/6/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Wang Lai	V8	O	Global H	S	-354	252.39	-1	0	1,704	D
6/10/25 16:55	6/6/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Wu Xiaobin	V8	O	P,COO	S	-490	253.15	-2	0	1,167	D
6/10/25 16:54	6/6/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Oyler John	V8	DO	CEO	S	-1,296	252.77	-5	0	54,152	D
6/10/25 16:45	6/6/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cramer Pamela J.	MA	O	CHRO	S.d	-478	68.05	-7	-27	19	D
6/10/25 16:39	6/9/25	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	Nichols Christian Todd	MA	O	SVP,Chie	S.m	-210	31.52	-7	-7	86	D
6/10/25 16:38	6/6/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pelish Henry E.	MA	O	Chief Sc	S.d	-16	79.82	0	0	63	D
6/10/25 16:30	6/9/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Edgemond James	MD	O	CFO,TREA	S.d	-3,904	325.38	-12	-60	8	D
6/9/25 20:49	6/6/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Savage William Jacob	MA	O	Chief Me	S	-150	50.00	-3	-5	57	D
6/9/25 20:18	6/6/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Piscitelli Dominic	CA	O	CFO	S.m	-29	10.01	-3	-3	104	D
6/9/25 17:30	6/5/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rolph Timothy	CA	O	Chief Sc	S.dm	-2,045	54.52	-38	-18	170	D
6/6/25 18:04	6/6/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Vazzano Joseph Walter	OH	O	CFO	S	-120	6.76	-18	-3	491	D
6/6/25 18:00	6/6/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Seshadri Vishwas	OH	DO	CEO	S	-343	6.76	-51	-4	1,304	D
6/6/25 17:58	6/5/25	XENE	Xenon Pharmaceuticals Inc.	A1	Health	Drug	Pharmaceutical Preparations	Gannon Steven	A1	D		S.d	0	30.48	0	0	7	D
6/6/25 17:56	6/6/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	O'Malley Brendan M.	OH	O	SVP,GC	S	-71	6.76	-10	-3	378	D
6/6/25 17:49	6/4/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Ramaswamy Vivek	DC	T		S.m	-8,455	11.30	-748	-1	51,784	D
6/6/25 16:53	6/5/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Smith Michael Alexander	NJ	O	GC	S	-138	73.50	-2	-3	68	D
6/6/25 16:47	6/5/25	KRON	Kronos Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Knobelman Deborah	MA	O	P,Interi	S	-22	0.8678	-25	-15	139	D
6/6/25 16:20	6/4/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Skorpios Trust	G4	T		S	-30,600	10.20	-3,000	-43	3,906	I
6/6/25 16:07	6/5/25	DYN	Dyne Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cox John	MA	DO	CEO,P	S	-54	13.35	-4	-2	174	D
6/6/25 16:05	6/5/25	DYN	Dyne Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kerr Douglas	MA	O	Chief Me	S	-18	13.35	-1	-1	93	D
6/6/25 16:03	6/5/25	DYN	Dyne Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Friedl-Naderer Johanna	MA	O	Chief Co	S	-2	13.35	0	0	96	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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