Orbimed Advisors LLC - Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	Title	T	TVal	Price	Qty	oc	Own	H
4/26/24 17:01	4/24/24	NPCE	Neuropace Inc	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	T		S	-25	14.06	-2	0	3,436	I
4/23/24 18:38	4/19/24	NPCE	Neuropace Inc	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	T		S.m	-913	14.12	-65	-2	3,437	I
4/18/24 17:10	4/16/24	NPCE	Neuropace Inc	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	T		S.m	-238	14.02	-17	0	3,502	I
4/15/24 17:25	4/11/24	NPCE	Neuropace Inc	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	T		S.m	-7,026	14.49	-485	-12	3,519	I
1/31/24 16:12	1/30/24	AVBP	Arrivent Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P.d	8,000	18.00	444	42	1,514	I
1/26/24 19:14	1/25/24	ACET	Adicet Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P	7,500	2.40	3,125		2,931	I
1/25/24 16:28	1/23/24	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P	5,000	11.00	455	3	14,756	I
12/29/23 16:18	12/27/23	ALPN	Alpine Immune Sciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D		S.m	-28,672	18.54	-1,546	-85	264	I
12/20/23 18:28	12/18/23	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D		M.d	66	38.00	2	0	1,702	D
12/20/23 18:28	12/18/23	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D		S.d	-102	59.24	-2	0	1,702	D
12/15/23 18:04	12/14/23	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D		S	-24,584	56.75	-433	-66	224	I
12/14/23 17:44	12/12/23	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D		S.m	-7,902	58.88	-134	-16	728	I
11/24/23 16:38	11/22/23	PMVP	Pmv Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T		S	-196	2.23	-88	-1	6,475	I
10/4/23 17:36	10/2/23	NPCE	Neuropace Inc	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	T		S.m	-75	9.07	-8	0	4,004	I
8/31/23 17:26	8/29/23	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D		P	3,100	6.20	500	6	9,241	I
8/17/23 16:40	8/15/23	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T		S	-617	0.7500	-823	-35	1,510	I
8/2/23 17:05	7/31/23	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T		S	-628	3.00	-209	-9	2,106	I
7/27/23 16:28	7/25/23	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T		S	-114	2.92	-39	-2	2,259	I
7/24/23 16:38	7/20/23	TSBX	Turnstone Biologics Corp.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	DT		P.d	5,000	12.00	417	16	3,099	I
7/19/23 16:15	7/17/23	THRX	Theseus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P	1,464	3.05	480	281	651	I
7/17/23 16:13	7/13/23	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T		S	-467	2.40	-195	-8	2,286	I
6/29/23 16:46	6/27/23	ACET	Adicet Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P	1,829	2.09	875	999%	962	I
6/29/23 16:42	6/27/23	PASG	Passage Bio, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T		P.m	1,002	0.8400	1,193	17	8,034	I
5/24/23 17:09	5/22/23	PRLD	Prelude Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P	5,000	5.75	870	9	10,646	I
5/19/23 16:19	5/17/23	ELVN	Enliven Therapeutics, Inc.		Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		M.d	9	4.28	2	0	8,951	I
5/15/23 18:07	5/11/23	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D		S.m	-9,938	20.58	-483	-11	3,778	I
5/8/23 17:22	5/4/23	KNTE	Kinnate Biopharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P.m	4,086	2.80	1,461	331	1,903	I
5/2/23 21:34	4/28/23	KNTE	Kinnate Biopharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P.m	3,674	2.61	1,405		1,329	I
4/21/23 17:08	4/19/23	TELA	Tela Bio, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	T		S.m	-1,792	9.34	-192	-6	2,836	I
4/17/23 17:28	4/13/23	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T		S.m	-128	1.87	-68	-3	2,418	I
4/12/23 18:44	4/10/23	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T		S.m	-121	1.80	-68	-3	2,464	I
4/7/23 16:42	4/5/23	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T		S.m	-222	2.16	-103	-4	2,510	I
2/17/23 16:43	2/15/23	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P	2,500	23.00	109	57	299	I
12/28/22 17:57	12/23/22	TERN	Terns Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P	1,000	7.25	138	2	7,619	I
12/27/22 17:38	12/22/22	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D		S.m	-136,001	22.15	-6,140	-15	34,086	I
11/29/22 16:36	11/25/22	SCPH	Scpharmaceuticals Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T		P	4,002	5.25	762	16	5,560	I
11/25/22 20:13	11/22/22	TCDA	Tricida, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		S.m	-2,206	0.2145	-10,281	-100	0	I
11/10/22 16:44	11/8/22	CMPX	Compass Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	DT		P	1,290	3.21	402	2	18,791	I
11/9/22 16:25	11/7/22	THRX	Theseus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P	1,000	5.21	192	1	17,234	I
9/21/22 18:00	9/19/22	THRD	Third Harmonic Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P.d	5,100	17.00	300	5	5,779	I
9/16/22 16:31	9/16/22	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P	5,000	10.32	484	4	14,302	I
9/14/22 16:24	9/12/22	SWTX	Springworks Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T		S	-4,919	31.96	-154	-3	5,600	I
8/18/22 17:00	8/16/22	TERN	Terns Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P.d	8,930	2.42	3,690		762	I
8/10/22 16:22	8/8/22	SWTX	Springworks Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T		S.m	-10,464	38.11	-275	-5	5,754	I
6/28/22 16:29	6/24/22	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T		S	-7,287	21.31	-342	-45	415	I
6/24/22 17:39	6/22/22	IKNA	Ikena Oncology, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	D		P.m	1,128	4.47	252	3	7,775	I
5/31/22 16:36	5/26/22	PMVP	Pmv Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T		S	-418	15.93	-26	0	6,563	I
5/20/22 16:38	5/18/22	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P	995	7.21	138	1	13,817	I
5/13/22 17:45	5/11/22	CMPX	Compass Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	DT		P.m	420	2.18	193	1	18,389	I
5/10/22 18:21	5/6/22	CMPX	Compass Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	DT		P.m	197	1.57	125	1	18,197	I
5/5/22 17:23	5/3/22	PASG	Passage Bio, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T		P.m	1,016	1.94	525	8	6,841	I
5/5/22 17:11	1/20/22	PASG	Passage Bio, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T		P.a	254	5.00	51	1	6,316	I
4/8/22 18:06	4/6/22	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T		S.m	-18,164	20.68	-878	-66	451	I
3/31/22 17:30	3/29/22	PMVP	Pmv Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T		S.m	-10,264	21.63	-475	-7	6,589	I
2/15/22 21:42	2/11/22	KNTE	Kinnate Biopharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D		P.m	1,989	10.17	196	5	4,044	I
1/27/22 17:22	1/25/22	ETNB	89Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T		S.m	-592	8.39	-71	-4	1,829	I
1/24/22 16:44	1/20/22	PASG	Passage Bio, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T		P	2,001	5.42	369	6	6,635	I
1/21/22 19:18	1/19/22	THRX	Theseus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P.m	1,579	9.97	158	1	17,042	I
1/20/22 18:03	1/14/22	PASG	Passage Bio, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T		P.m	905	5.38	168	3	6,266	I
1/13/22 19:37	1/11/22	PASG	Passage Bio, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T		P.m	841	5.61	150	3	6,097	I
1/13/22 19:18	1/11/22	THRX	Theseus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P.m	443	9.90	45	0	16,883	I
12/30/21 21:00	12/29/21	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D		S	-820	20.30	-40	-15	231	I
12/23/21 16:13	12/21/21	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D		S	-2,269	19.00	-119	-34	235	I
12/17/21 17:13	12/16/21	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D		S	-7,500	19.07	-393	-62	246	I
11/8/21 21:06	11/4/21	CMPX	Compass Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	DT		P	18,750	3.50	5,357		3,571	I
10/14/21 17:00	10/12/21	THRX	Theseus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P.d	10,000	16.00	625	4	16,839	I
9/22/21 17:27	9/20/21	CRVS	Corvus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		S	-6,758	6.09	-1,110	-14	6,944	I
9/21/21 18:42	9/17/21	ALPN	Alpine Immune Sciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P	9,500	9.40	1,011		426	I
9/8/21 18:18	9/3/21	RPTX	Repare Therapeutics Inc.	Z4	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D		S.m	-275	33.99	-8	-8	96	I
9/2/21 20:27	8/31/21	RPTX	Repare Therapeutics Inc.	Z4	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D		S.m	-1,291	34.08	-38	-28	96	I
8/30/21 18:37	8/26/21	RPTX	Repare Therapeutics Inc.	Z4	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D		S.m	-616	34.07	-18	-16	98	I
8/25/21 20:43	8/23/21	RPTX	Repare Therapeutics Inc.	Z4	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D		S.m	-622	34.17	-18	-16	98	I
8/19/21 20:55	8/17/21	RPTX	Repare Therapeutics Inc.	Z4	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D		S.m	-693	34.10	-20	-17	99	I
7/23/21 17:30	7/16/21	IMRA	Imara Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P.a	10,000	6.00	1,667	66	4,199	I
7/21/21 17:30	7/19/21	AFIB	Acutus Medical, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	DT		P	15,000	14.00	1,071	176	1,681	I
7/16/21 16:27	7/16/21	IMRA	Imara Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P	10,000	6.00	1,667	66	4,199	I
7/6/21 16:42	7/1/21	SWTX	Springworks Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T		S	-1,357	85.01	-16	0	6,028	I
6/30/21 21:01	6/28/21	SWTX	Springworks Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T		S	-554	85.17	-7	0	6,044	I
6/25/21 19:11	6/23/21	SWTX	Springworks Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T		S.m	-4,825	85.19	-57	-1	6,051	I
6/16/21 18:17	6/15/21	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D		P.d	12,000	17.00	706		282	I
6/14/21 17:58	6/10/21	SWTX	Springworks Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T		S	-2,625	85.09	-31	-1	6,107	I
6/9/21 18:26	6/7/21	SWTX	Springworks Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T		S.m	-4,102	85.36	-48	-1	6,138	I
4/23/21 20:32	4/21/21	NPCE	Neuropace Inc	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	T		P	3,995	17.00	235	New	235	I
4/13/21 18:36	3/30/21	IKNA	Ikena Oncology, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	D		P.ad	6,774	16.00	423		248	I
4/1/21 18:13	3/30/21	IKNA	Ikena Oncology, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	D		P.d	6,774	16.00	423		248	I
3/31/21 19:10	3/30/21	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P.d	5,750	16.00	359	3	13,359	I
3/31/21 17:08	3/29/21	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D		S.m	-2,428	23.48	-103	-4	2,213	I
3/26/21 17:51	3/24/21	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D		S.m	-2,754	24.53	-112	-5	2,316	I
3/23/21 17:22	3/19/21	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D		S.m	-863	26.21	-33	-1	2,428	I
3/18/21 21:07	3/16/21	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D		S.m	-1,850	27.95	-66	-3	2,461	I
3/15/21 20:55	3/11/21	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D		S.m	-7,276	30.54	-238	-9	2,527	I
3/3/21 18:55	3/1/21	SWTX	Springworks Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T		S	-101,492	83.19	-1,220	-16	6,186	I
2/19/21 19:09	2/17/21	DBTX	Decibel Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P.d	30,000	18.00	1,667		883	I
2/19/21 16:52	2/17/21	CRVS	Corvus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P	4,500	3.50	1,286	19	8,053	I
2/9/21 15:09	2/9/21	TERN	Terns Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P.d	8,075	17.00	475	26	2,275	I
1/11/21 16:46	1/7/21	CTIC	Cti Biopharma Corp	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T		S	-7,000	3.50	-2,000	-21	7,521	I
12/30/20 16:44	12/28/20	ALPN	Alpine Immune Sciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		S	-8,550	14.25	-600	-16	3,071	I
12/10/20 17:04	12/8/20	ARPO	Aerpio Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T		S.d	-42	1.96	-21	0	5,194	I
12/8/20 20:41	12/8/20	SBTX	Silverback Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P.d	25,000	21.00	1,190	16	8,741	I
12/4/20 18:11	12/2/20	KNTE	Kinnate Biopharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P	15,000	20.00	750		450	I
11/4/20 20:00	11/2/20	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P.d	11,000	15.00	733	246	1,032	I
10/6/20 17:27	10/2/20	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P	12,400	25.00	496	122	902	I
10/5/20 17:36	10/1/20	LOGC	Logicbio Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	DT		P	8,889	6.00	1,481		296	I
9/29/20 20:10	9/25/20	PRLD	Prelude Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P.d	23,499	19.00	1,237	15	9,250	I
9/29/20 16:41	9/25/20	GRAY	Graybug Vision, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T		P.d	9,000	16.00	563	16	4,163	I
9/29/20 16:39	9/25/20	PMVP	Pmv Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P.d	17,100	18.00	950		475	I
9/23/20 17:09	9/21/20	ETNB	89Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		S	-7,700	28.00	-275	-13	1,865	I
8/19/20 17:24	8/17/20	INSP	Inspire Medical Systems, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	D		S.m	-14,927	107.82	-138	-99	2	I
8/14/20 17:19	8/12/20	INSP	Inspire Medical Systems, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	D		S.m	-10,010	108.58	-92	-40	140	I
8/12/20 21:06	8/10/20	AFIB	Acutus Medical, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	DT		P.d	7,470	18.00	415	46	1,320	I
8/11/20 18:23	8/7/20	INSP	Inspire Medical Systems, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	D		S.m	-12,316	105.65	-117	-33	232	I
7/2/20 16:02	6/30/20	FUSN	Fusion Pharmaceuticals Inc.	Z4	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	D		P.d	15,266	17.00	898	40	3,123	I
6/25/20 17:53	6/23/20	RPTX	Repare Therapeutics Inc.	Z4	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D		P.d	15,484	20.00	774	30	3,376	I
5/26/20 16:44	5/21/20	SCPH	Scpharmaceuticals Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T		P	12,000	8.65	1,387		231	I
4/28/20 17:13	4/24/20	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P.d	4,500	16.00	281	11	2,766	I
4/16/20 20:23	4/14/20	ALEC	Alector, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T		S.m	-2,010	23.53	-85	-4	1,907	I
4/13/20 17:17	4/13/20	KROS	Keros Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D		P.d	6,003	16.00	375	50	1,120	I
4/9/20 17:30	4/7/20	ALEC	Alector, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T		S.m	-9,020	23.74	-380	-16	1,927	I
4/2/20 17:06	3/31/20	ALEC	Alector, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T		S	-6,125	24.50	-250	-11	2,020	I
3/25/20 17:54	3/23/20	ALEC	Alector, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T		S.m	-3,425	24.70	-139	-6	2,080	I
3/16/20 17:06	3/12/20	IMRA	Imara Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P.d	15,000	16.00	938	59	2,532	I
3/10/20 17:06	3/6/20	INSP	Inspire Medical Systems, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	D		S	-41,760	83.52	-500	-59	348	I
3/5/20 18:34	3/3/20	INSP	Inspire Medical Systems, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	D		S	-42,123	84.25	-500	-37	848	I
3/4/20 16:17	3/2/20	ALEC	Alector, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T		S	-48,729	26.00	-1,874	-100	0	I
3/3/20 19:07	2/28/20	PASG	Passage Bio, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T		P.d	6,719	18.00	373	7	5,947	I
2/4/20 17:30	2/3/20	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P.d	9,501	17.00	559	999%	606	I
1/13/20 16:48	1/9/20	ALEC	Alector, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T		S	-7,410	19.50	-380	-91	39	I
12/26/19 16:54	12/20/19	ALEC	Alector, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T		S.m	-10,210	19.66	-519	-93	40	I
12/19/19 16:33	12/17/19	ALEC	Alector, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T		S	-17,670	18.52	-954	-91	98	I
12/12/19 17:20	12/11/19	TCDA	Tricida, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		S	-60,000	40.00	-1,500	-13	9,620	I
11/29/19 11:56	11/26/19	INSP	Inspire Medical Systems, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	D		S.m	-8,766	70.69	-124	-8	1,348	I
11/13/19 20:47	11/8/19	TELA	Tela Bio, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	T		P.d	5,000	13.00	385	15	3,028	D
11/13/19 19:00	11/11/19	ETNB	89Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P.d	13,400	16.00	838	72	2,002	I
9/19/19 19:12	9/17/19	SWTX	Springworks Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	CT	T		P.d	4,950	18.00	275	4	7,406	I
8/9/19 18:41	8/7/19	ALEC	Alector, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T		S	-11,635	17.90	-650	-17	3,172	I
8/8/19 16:59	8/6/19	CRVS	Corvus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P	501	3.51	143	2	6,768	I
7/1/19 18:15	6/27/19	CRVS	Corvus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P.m	2,444	3.72	657	11	6,625	I
6/26/19 16:54	6/24/19	PRVL	Prevail Therapeutics Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	DT		P.d	15,000	17.00	882	7	13,822	I
5/22/19 12:43	5/21/19	PRNB	Principia Biopharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T		S	-30,250	30.25	-1,000	-38	1,606	I
5/13/19 19:32	5/13/19	NXTC	Nextcure, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	MD	DT		P.d	5,250	15.00	350	15	2,711	I
4/24/19 18:16	4/22/19	TPTX	Turning Point Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	CA	D		P.d	6,480	18.00	360	22	2,028	I
4/5/19 15:24	4/3/19	TCDA	Tricida, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P	8,100	36.00	225	2	11,114	I
3/11/19 21:30	3/7/19	INSP	Inspire Medical Systems, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	D		S.m	-20,514	57.23	-358	-20	1,472	I
2/11/19 19:11	2/11/19	ALEC	Alector, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	DT		P.d	7,822	19.00	412		203	I
1/23/19 17:58	1/18/19	ALPN	Alpine Immune Sciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P.d	2,000	5.37	372	11	3,671	I
12/13/18 18:33	12/11/18	THOR	Synthorx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P.d	15,000	11.00	1,364	34	5,316	I
12/13/18 16:35	12/11/18	INSP	Inspire Medical Systems, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	D		S	-23,115	37.60	-615	-100	0	I
10/25/18 18:28	10/23/18	LOGC	Logicbio Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	DT		P.d	11,900	10.00	1,190	23	6,467	I
10/19/18 16:52	10/19/18	SIBN	Si-Bone, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	D		P.d	3,000	15.00	200	25	985	I
9/20/18 18:59	9/18/18	PRNB	Principia Biopharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T		P.d	4,250	17.00	250	11	2,606	I
9/7/18 17:05	8/30/18	STDY	Steadymed Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T		S.d	-18,938	4.46	-4,246	-100	0	I
8/21/18 19:44	8/13/18	VRAY	Viewray, Inc.	DE	Health	ElcMd	Electromedical & Electrothera	Orbimed Advisors LLC	NY	T		S.am	-1,851	9.95	-186	-72	74	I
8/21/18 19:36	8/16/18	VRAY	Viewray, Inc.	DE	Health	ElcMd	Electromedical & Electrothera	Orbimed Advisors LLC	NY	T		S.am	-6,712	9.96	-674	-91	69	I
8/20/18 19:19	8/16/18	VRAY	Viewray, Inc.	DE	Health	ElcMd	Electromedical & Electrothera	Orbimed Advisors LLC	NY	T		S.m	-5,191	9.95	-522	-88	70	I
8/15/18 19:49	8/13/18	VRAY	Viewray, Inc.	DE	Health	ElcMd	Electromedical & Electrothera	Orbimed Advisors LLC	NY	T		S.m	-1,851	9.95	-186	-71	75	I
8/10/18 19:36	8/7/18	VRAY	Viewray, Inc.	DE	Health	ElcMd	Electromedical & Electrothera	Orbimed Advisors LLC	NY	T		M.dm	326	3.56	92		76	I
8/10/18 19:36	8/8/18	VRAY	Viewray, Inc.	DE	Health	ElcMd	Electromedical & Electrothera	Orbimed Advisors LLC	NY	T		S.dm	-13,646	9.97	-1,369	-95	76	I
8/7/18 18:12	8/3/18	VRAY	Viewray, Inc.	DE	Health	ElcMd	Electromedical & Electrothera	Orbimed Advisors LLC	NY	T		S.m	-1,904	11.20	-170	-66	88	I
7/24/18 16:46	7/23/18	CNST	Constellation Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T		P.d	3,000	15.00	200	92	418	I
7/2/18 21:11	7/2/18	TCDA	Tricida, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P.d	7,000	19.00	368	4	10,889	I
7/2/18 16:56	6/28/18	ARPO	Aerpio Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P	2,993	3.85	778	18	5,194	I
6/6/18 18:10	6/4/18	ADAP	Adaptimmune Therapeutics Plc	X0	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	D		S.m	-254	13.56	-19	0	4,901	I
6/1/18 17:25	5/30/18	ADAP	Adaptimmune Therapeutics Plc	X0	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	D		S.m	-2,310	13.51	-171	-3	4,920	I
5/24/18 16:13	5/22/18	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	TH	See Rema	S	-596	30.43	-20	-1	2,750	I
5/21/18 18:15	5/18/18	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T		S.m	-4,065	30.88	-132	-5	2,770	I
5/16/18 17:22	5/14/18	ADAP	Adaptimmune Therapeutics Plc	X0	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	D		S	-139	13.50	-10	0	5,091	I
5/9/18 21:21	5/7/18	INSP	Inspire Medical Systems, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	T		P.d	5,000	16.00	313	15	2,444	D
5/2/18 17:13	4/30/18	PIRS	Pieris Pharmaceuticals, Inc.	NV	Health	Biolab	Commercial Physical & Biologi	Orbimed Advisors LLC	NY	TH	See Rema	S	-6,350	6.35	-1,000	-96	39	I
3/29/18 18:54	3/27/18	ADAP	Adaptimmune Therapeutics Plc	X0	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	D		S.m	-12,054	11.50	-1,048	-17	5,101	I
3/14/18 13:58	3/12/18	CRVS	Corvus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P	5,000	8.50	588	11	5,968	I
3/12/18 18:16	3/8/18	BOLD	Audentes Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T		S.m	-5,470	34.97	-156	-4	3,540	I
3/6/18 19:36	3/2/18	GKOS	Glaukos Corp	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	D		S.m	-26,787	32.02	-837	-100	0	I
3/6/18 17:53	3/2/18	BOLD	Audentes Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T		S.m	-15,211	35.11	-433	-10	3,696	I
2/23/18 18:55	2/14/18	XTNT	Xtant Medical Holdings, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	DT		P.d	6,810	7.20	946	40	3,316	I
2/15/18 16:57	2/13/18	PIRS	Pieris Pharmaceuticals, Inc.	NV	Health	Biolab	Commercial Physical & Biologi	Orbimed Advisors LLC	NY	T		M.d	38	4.77	8	19	49	I
2/15/18 16:57	2/13/18	PIRS	Pieris Pharmaceuticals, Inc.	NV	Health	Biolab	Commercial Physical & Biologi	Orbimed Advisors LLC	NY	T		S.d	-71	8.98	-8	-14	49	I
2/12/18 16:35	2/8/18	KALA	Kala Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T		P	323	12.93	25	1	3,448	I
2/6/18 17:05	2/2/18	KALA	Kala Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T		P	557	14.73	38	1	3,423	I
2/2/18 17:45	1/31/18	KALA	Kala Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T		P.m	5,433	15.00	362	12	3,385	I
1/30/18 18:41	1/30/18	TORC	Restorbio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		P.d	8,000	15.00	533	12	4,830	I
1/30/18 15:34	1/26/18	KALA	Kala Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T		P.m	1,089	14.97	73	2	3,023	I
1/24/18 20:59	1/12/18	KALA	Kala Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T		P.m	3,829	14.88	257	10	2,950	I
1/12/18 17:29	1/10/18	KALA	Kala Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T		P.m	3,193	13.28	240	10	2,693	I
1/4/18 15:23	1/3/18	PIRS	Pieris Pharmaceuticals, Inc.	NV	Health	Biolab	Commercial Physical & Biologi	Orbimed Advisors LLC	NY	T		S	-12,566	7.35	-1,710	-97	49	I
12/20/17 17:12	12/18/17	PIRS	Pieris Pharmaceuticals, Inc.	NV	Health	Biolab	Commercial Physical & Biologi	Orbimed Advisors LLC	NY	T		M.d	308	2.09	148		65	I
12/20/17 17:12	12/18/17	PIRS	Pieris Pharmaceuticals, Inc.	NV	Health	Biolab	Commercial Physical & Biologi	Orbimed Advisors LLC	NY	T		S.d	-842	5.70	-148	-69	65	I
12/12/17 14:02	12/8/17	LOXO	Loxo Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D		S	-20,625	82.50	-250	-21	941	I
11/27/17 15:30	11/22/17	LOXO	Loxo Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D		S	-20,025	75.00	-267	-18	1,191	I
11/21/17 19:13	11/21/17	SCPH	Scpharmaceuticals Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	MA	T		P.d	11,667	14.00	833	32	3,410	I
11/20/17 19:31	11/16/17	LOXO	Loxo Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D		S	-20,051	74.26	-270	-16	1,458	I
10/10/17 16:21	10/10/17	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T		P.d	6,035	17.00	355	14	2,901	I
10/5/17 15:52	10/3/17	ROKA	Roka Bioscience, Inc.	DE	Electr	LabEq	Laboratory Analytical Instrum	Orbimed Advisors LLC	NY	T		S	-137	0.6800	-202	-100	0	I
10/2/17 16:07	9/28/17	ROKA	Roka Bioscience, Inc.	DE	Electr	LabEq	Laboratory Analytical Instrum	Orbimed Advisors LLC	NY	T		S.m	-344	0.7240	-475	-100	2	I
9/29/17 18:06	9/29/17	BOLD	Audentes Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T		S	-18,984	28.25	-672	-14	4,130	I
9/28/17 17:31	9/26/17	ROKA	Roka Bioscience, Inc.	DE	Electr	LabEq	Laboratory Analytical Instrum	Orbimed Advisors LLC	NY	T		S.m	-126	0.9845	-128	-95	6	I
9/11/17 14:16	9/7/17	BOLD	Audentes Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T		S.d	-112	22.35	-5	0	4,802	I
9/5/17 21:27	8/31/17	GKOS	Glaukos Corp	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	D		S.m	-22,473	38.73	-580	-99	8	I
8/25/17 15:30	8/23/17	ROKA	Roka Bioscience, Inc.	DE	Electr	LabEq	Laboratory Analytical Instrum	Orbimed Advisors LLC	NY	T		S.m	-21	1.50	-14	-65	8	I
8/22/17 20:27	8/18/17	ROKA	Roka Bioscience, Inc.	DE	Electr	LabEq	Laboratory Analytical Instrum	Orbimed Advisors LLC	NY	T		S.m	-114	1.52	-75	-91	8	I
8/17/17 17:20	8/15/17	GKOS	Glaukos Corp	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	D		S.m	-12,326	37.93	-325	-96	13	I

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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