Orbimed Advisors LLC - Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	T	TVal	Price	Qty	oc	Own	H
5/3/24 17:16	5/1/24	NPCE	Neuropace Inc	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	T	S.m	-409	14.02	-29	-1	3,406	I
4/26/24 17:01	4/24/24	NPCE	Neuropace Inc	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	T	S	-25	14.06	-2	0	3,436	I
4/23/24 18:38	4/19/24	NPCE	Neuropace Inc	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	T	S.m	-913	14.12	-65	-2	3,437	I
4/18/24 17:10	4/16/24	NPCE	Neuropace Inc	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	T	S.m	-238	14.02	-17	0	3,502	I
4/15/24 17:25	4/11/24	NPCE	Neuropace Inc	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	T	S.m	-7,026	14.49	-485	-12	3,519	I
1/31/24 16:12	1/30/24	AVBP	Arrivent Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P.d	8,000	18.00	444	42	1,514	I
1/26/24 19:14	1/25/24	ACET	Adicet Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P	7,500	2.40	3,125		2,931	I
1/25/24 16:28	1/23/24	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P	5,000	11.00	455	3	14,756	I
12/29/23 16:18	12/27/23	ALPN	Alpine Immune Sciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	S.m	-28,672	18.54	-1,546	-85	264	I
12/20/23 18:28	12/18/23	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	M.d	66	38.00	2	0	1,702	D
12/20/23 18:28	12/18/23	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	S.d	-102	59.24	-2	0	1,702	D
12/15/23 18:04	12/14/23	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	S	-24,584	56.75	-433	-66	224	I
12/14/23 17:44	12/12/23	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	S.m	-7,902	58.88	-134	-16	728	I
11/24/23 16:38	11/22/23	PMVP	Pmv Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T	S	-196	2.23	-88	-1	6,475	I
10/4/23 17:36	10/2/23	NPCE	Neuropace Inc	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	T	S.m	-75	9.07	-8	0	4,004	I
8/31/23 17:26	8/29/23	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	P	3,100	6.20	500	6	9,241	I
8/17/23 16:40	8/15/23	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T	S	-617	0.7500	-823	-35	1,510	I
8/2/23 17:05	7/31/23	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T	S	-628	3.00	-209	-9	2,106	I
7/27/23 16:28	7/25/23	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T	S	-114	2.92	-39	-2	2,259	I
7/24/23 16:38	7/20/23	TSBX	Turnstone Biologics Corp.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	DT	P.d	5,000	12.00	417	16	3,099	I
7/19/23 16:15	7/17/23	THRX	Theseus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P	1,464	3.05	480	281	651	I
7/17/23 16:13	7/13/23	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T	S	-467	2.40	-195	-8	2,286	I
6/29/23 16:46	6/27/23	ACET	Adicet Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P	1,829	2.09	875	999%	962	I
6/29/23 16:42	6/27/23	PASG	Passage Bio, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T	P.m	1,002	0.8400	1,193	17	8,034	I
5/24/23 17:09	5/22/23	PRLD	Prelude Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P	5,000	5.75	870	9	10,646	I
5/19/23 16:19	5/17/23	ELVN	Enliven Therapeutics, Inc.		Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	M.d	9	4.28	2	0	8,951	I
5/15/23 18:07	5/11/23	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	S.m	-9,938	20.58	-483	-11	3,778	I
5/8/23 17:22	5/4/23	KNTE	Kinnate Biopharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P.m	4,086	2.80	1,461	331	1,903	I
5/2/23 21:34	4/28/23	KNTE	Kinnate Biopharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P.m	3,674	2.61	1,405		1,329	I
4/21/23 17:08	4/19/23	TELA	Tela Bio, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	T	S.m	-1,792	9.34	-192	-6	2,836	I
4/17/23 17:28	4/13/23	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T	S.m	-128	1.87	-68	-3	2,418	I
4/12/23 18:44	4/10/23	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T	S.m	-121	1.80	-68	-3	2,464	I
4/7/23 16:42	4/5/23	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T	S.m	-222	2.16	-103	-4	2,510	I
2/17/23 16:43	2/15/23	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P	2,500	23.00	109	57	299	I
12/28/22 17:57	12/23/22	TERN	Terns Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P	1,000	7.25	138	2	7,619	I
12/27/22 17:38	12/22/22	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	S.m	-136,001	22.15	-6,140	-15	34,086	I
11/29/22 16:36	11/25/22	SCPH	Scpharmaceuticals Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T	P	4,002	5.25	762	16	5,560	I
11/25/22 20:13	11/22/22	TCDA	Tricida, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	S.m	-2,206	0.2145	-10,281	-100	0	I
11/10/22 16:44	11/8/22	CMPX	Compass Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	DT	P	1,290	3.21	402	2	18,791	I
11/9/22 16:25	11/7/22	THRX	Theseus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P	1,000	5.21	192	1	17,234	I
9/21/22 18:00	9/19/22	THRD	Third Harmonic Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P.d	5,100	17.00	300	5	5,779	I
9/16/22 16:31	9/16/22	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P	5,000	10.32	484	4	14,302	I
9/14/22 16:24	9/12/22	SWTX	Springworks Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T	S	-4,919	31.96	-154	-3	5,600	I
8/18/22 17:00	8/16/22	TERN	Terns Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P.d	8,930	2.42	3,690		762	I
8/10/22 16:22	8/8/22	SWTX	Springworks Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T	S.m	-10,464	38.11	-275	-5	5,754	I
6/28/22 16:29	6/24/22	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T	S	-7,287	21.31	-342	-45	415	I
6/24/22 17:39	6/22/22	IKNA	Ikena Oncology, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	D	P.m	1,128	4.47	252	3	7,775	I
5/31/22 16:36	5/26/22	PMVP	Pmv Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T	S	-418	15.93	-26	0	6,563	I
5/20/22 16:38	5/18/22	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P	995	7.21	138	1	13,817	I
5/13/22 17:45	5/11/22	CMPX	Compass Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	DT	P.m	420	2.18	193	1	18,389	I
5/10/22 18:21	5/6/22	CMPX	Compass Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	DT	P.m	197	1.57	125	1	18,197	I
5/5/22 17:23	5/3/22	PASG	Passage Bio, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T	P.m	1,016	1.94	525	8	6,841	I
5/5/22 17:11	1/20/22	PASG	Passage Bio, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T	P.a	254	5.00	51	1	6,316	I
4/8/22 18:06	4/6/22	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T	S.m	-18,164	20.68	-878	-66	451	I
3/31/22 17:30	3/29/22	PMVP	Pmv Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T	S.m	-10,264	21.63	-475	-7	6,589	I
2/15/22 21:42	2/11/22	KNTE	Kinnate Biopharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	P.m	1,989	10.17	196	5	4,044	I
1/27/22 17:22	1/25/22	ETNB	89Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T	S.m	-592	8.39	-71	-4	1,829	I
1/24/22 16:44	1/20/22	PASG	Passage Bio, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T	P	2,001	5.42	369	6	6,635	I
1/21/22 19:18	1/19/22	THRX	Theseus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P.m	1,579	9.97	158	1	17,042	I
1/20/22 18:03	1/14/22	PASG	Passage Bio, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T	P.m	905	5.38	168	3	6,266	I
1/13/22 19:37	1/11/22	PASG	Passage Bio, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T	P.m	841	5.61	150	3	6,097	I
1/13/22 19:18	1/11/22	THRX	Theseus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P.m	443	9.90	45	0	16,883	I
12/30/21 21:00	12/29/21	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	S	-820	20.30	-40	-15	231	I
12/23/21 16:13	12/21/21	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	S	-2,269	19.00	-119	-34	235	I
12/17/21 17:13	12/16/21	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	S	-7,500	19.07	-393	-62	246	I
11/8/21 21:06	11/4/21	CMPX	Compass Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	DT	P	18,750	3.50	5,357		3,571	I
10/14/21 17:00	10/12/21	THRX	Theseus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P.d	10,000	16.00	625	4	16,839	I
9/22/21 17:27	9/20/21	CRVS	Corvus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	S	-6,758	6.09	-1,110	-14	6,944	I
9/21/21 18:42	9/17/21	ALPN	Alpine Immune Sciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P	9,500	9.40	1,011		426	I
9/8/21 18:18	9/3/21	RPTX	Repare Therapeutics Inc.	Z4	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	S.m	-275	33.99	-8	-8	96	I
9/2/21 20:27	8/31/21	RPTX	Repare Therapeutics Inc.	Z4	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	S.m	-1,291	34.08	-38	-28	96	I
8/30/21 18:37	8/26/21	RPTX	Repare Therapeutics Inc.	Z4	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	S.m	-616	34.07	-18	-16	98	I
8/25/21 20:43	8/23/21	RPTX	Repare Therapeutics Inc.	Z4	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	S.m	-622	34.17	-18	-16	98	I
8/19/21 20:55	8/17/21	RPTX	Repare Therapeutics Inc.	Z4	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	S.m	-693	34.10	-20	-17	99	I

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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