Orbimed Advisors LLC - Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	T	TVal	Price	Qty	oc	Own	H
2/10/25 16:28	2/10/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	P.d	9,900	18.00	550	17	3,705	I
1/14/25 17:17	1/10/25	PASG	Passage Bio, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T	S.m	-142	0.6371	-223	-3	7,035	I
1/8/25 18:09	1/6/25	PASG	Passage Bio, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T	S.m	-103	0.7026	-147	-2	7,258	I
12/26/24 16:34	12/20/24	PASG	Passage Bio, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T	S	-138	0.6000	-230	-3	7,405	I
12/11/24 17:32	12/9/24	PASG	Passage Bio, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T	S.m	-52	0.8348	-62	-1	7,635	I
12/6/24 19:07	12/4/24	PASG	Passage Bio, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T	S.m	-77	0.7965	-97	-1	7,697	I
10/17/24 16:17	10/15/24	UPB	Upstream Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P.d	14,025	17.00	825	22	4,555	I
9/23/24 16:51	9/19/24	PASG	Passage Bio, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T	S	-28	0.7100	-39	-1	7,795	I
9/18/24 18:38	9/16/24	PASG	Passage Bio, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T	S.m	-147	0.7332	-200	-2	7,834	I
9/17/24 20:13	9/16/24	MBX	Mbx Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P.d	12,000	16.00	750	24	3,812	I
8/28/24 16:26	8/26/24	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	S	-1,088	13.00	-84	-1	8,289	I
8/23/24 18:38	8/21/24	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	S.m	-11,498	13.24	-869	-9	8,372	I
8/15/24 17:01	8/13/24	KROS	Keros Therapeutics, Inc.		Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	S	-11,003	44.01	-250	-68	120	I
8/15/24 16:51	8/13/24	SCPH	Scpharmaceuticals Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T	P	2,000	4.00	500		253	I
7/17/24 20:48	7/15/24	TERN	Terns Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	S.m	-562	10.00	-56	-7	756	I
7/2/24 16:54	6/28/24	TELA	Tela Bio, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	T	S.m	-2,022	4.72	-428	-15	2,407	I
6/20/24 17:19	6/17/24	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	P	3,000	36.00	83	55	235	I
5/20/24 17:00	5/16/24	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	S	-22,877	22.14	-1,033	-12	7,663	I
5/3/24 17:16	5/1/24	NPCE	Neuropace Inc	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	T	S.m	-409	14.02	-29	-1	3,406	I
4/26/24 17:01	4/24/24	NPCE	Neuropace Inc	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	T	S	-25	14.06	-2	0	3,436	I
4/23/24 18:38	4/19/24	NPCE	Neuropace Inc	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	T	S.m	-913	14.12	-65	-2	3,437	I
4/18/24 17:10	4/16/24	NPCE	Neuropace Inc	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	T	S.m	-238	14.02	-17	0	3,502	I
4/15/24 17:25	4/11/24	NPCE	Neuropace Inc	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	T	S.m	-7,026	14.49	-485	-12	3,519	I
1/31/24 16:12	1/30/24	AVBP	Arrivent Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P.d	8,000	18.00	444	42	1,514	I
1/26/24 19:14	1/25/24	ACET	Adicet Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P	7,500	2.40	3,125		2,931	I
1/25/24 16:28	1/23/24	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P	5,000	11.00	455	3	14,756	I
12/29/23 16:18	12/27/23	ALPN	Alpine Immune Sciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	S.m	-28,672	18.54	-1,546	-85	264	I
12/20/23 18:28	12/18/23	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	M.d	66	38.00	2	0	1,702	D
12/20/23 18:28	12/18/23	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	S.d	-102	59.24	-2	0	1,702	D
12/15/23 18:04	12/14/23	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	S	-24,584	56.75	-433	-66	224	I
12/14/23 17:44	12/12/23	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	S.m	-7,902	58.88	-134	-16	728	I
11/24/23 16:38	11/22/23	PMVP	Pmv Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T	S	-196	2.23	-88	-1	6,475	I
10/4/23 17:36	10/2/23	NPCE	Neuropace Inc	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	T	S.m	-75	9.07	-8	0	4,004	I
8/31/23 17:26	8/29/23	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	P	3,100	6.20	500	6	9,241	I
8/17/23 16:40	8/15/23	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T	S	-617	0.7500	-823	-35	1,510	I
8/2/23 17:05	7/31/23	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T	S	-628	3.00	-209	-9	2,106	I
7/27/23 16:28	7/25/23	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T	S	-114	2.92	-39	-2	2,259	I
7/24/23 16:38	7/20/23	TSBX	Turnstone Biologics Corp.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	DT	P.d	5,000	12.00	417	16	3,099	I
7/19/23 16:15	7/17/23	THRX	Theseus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P	1,464	3.05	480	281	651	I
7/17/23 16:13	7/13/23	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T	S	-467	2.40	-195	-8	2,286	I
6/29/23 16:46	6/27/23	ACET	Adicet Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P	1,829	2.09	875	999%	962	I
6/29/23 16:42	6/27/23	PASG	Passage Bio, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T	P.m	1,002	0.8400	1,193	17	8,034	I
5/24/23 17:09	5/22/23	PRLD	Prelude Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P	5,000	5.75	870	9	10,646	I
5/19/23 16:19	5/17/23	ELVN	Enliven Therapeutics, Inc.		Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	M.d	9	4.28	2	0	8,951	I
5/15/23 18:07	5/11/23	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	S.m	-9,938	20.58	-483	-11	3,778	I
5/8/23 17:22	5/4/23	KNTE	Kinnate Biopharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P.m	4,086	2.80	1,461	331	1,903	I
5/2/23 21:34	4/28/23	KNTE	Kinnate Biopharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P.m	3,674	2.61	1,405		1,329	I
4/21/23 17:08	4/19/23	TELA	Tela Bio, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Orbimed Advisors LLC	NY	T	S.m	-1,792	9.34	-192	-6	2,836	I
4/17/23 17:28	4/13/23	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T	S.m	-128	1.87	-68	-3	2,418	I
4/12/23 18:44	4/10/23	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T	S.m	-121	1.80	-68	-3	2,464	I
4/7/23 16:42	4/5/23	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T	S.m	-222	2.16	-103	-4	2,510	I
2/17/23 16:43	2/15/23	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P	2,500	23.00	109	57	299	I
12/28/22 17:57	12/23/22	TERN	Terns Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P	1,000	7.25	138	2	7,619	I
12/27/22 17:38	12/22/22	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D	S.m	-136,001	22.15	-6,140	-15	34,086	I
11/29/22 16:36	11/25/22	SCPH	Scpharmaceuticals Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T	P	4,002	5.25	762	16	5,560	I
11/25/22 20:13	11/22/22	TCDA	Tricida, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	S.m	-2,206	0.2145	-10,281	-100	0	I
11/10/22 16:44	11/8/22	CMPX	Compass Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	DT	P	1,290	3.21	402	2	18,791	I
11/9/22 16:25	11/7/22	THRX	Theseus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P	1,000	5.21	192	1	17,234	I
9/21/22 18:00	9/19/22	THRD	Third Harmonic Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P.d	5,100	17.00	300	5	5,779	I
9/16/22 16:31	9/16/22	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P	5,000	10.32	484	4	14,302	I
9/14/22 16:24	9/12/22	SWTX	Springworks Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T	S	-4,919	31.96	-154	-3	5,600	I
8/18/22 17:00	8/16/22	TERN	Terns Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P.d	8,930	2.42	3,690		762	I
8/10/22 16:22	8/8/22	SWTX	Springworks Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	T	S.m	-10,464	38.11	-275	-5	5,754	I
6/28/22 16:29	6/24/22	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T	S	-7,287	21.31	-342	-45	415	I
6/24/22 17:39	6/22/22	IKNA	Ikena Oncology, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Orbimed Advisors LLC	NY	D	P.m	1,128	4.47	252	3	7,775	I
5/31/22 16:36	5/26/22	PMVP	Pmv Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T	S	-418	15.93	-26	0	6,563	I
5/20/22 16:38	5/18/22	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT	P	995	7.21	138	1	13,817	I

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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