11/13/25 08:52 | 11/12/25 | CRVO | Cervomed Inc. | DE | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | DOT | CEO,P | P | 41 | 7.35 | 0 | 6 | 0 | 1,467 | D | | | | | | | | | | | | | | |
10/2/08 11:02 | 10/1/08 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Med. | M.d | 58 | 13.63 | 33 | 4 | 3 | 142 | D | -3 | -13 | 29 | -4 | 24 | 17 | 18 | -4 | -5 | -19 | -24 | -7 | -13 | 5 |
10/2/08 11:02 | 10/1/08 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Med. | S.d | -139 | 32.65 | 33 | -4 | -3 | 142 | D | -3 | -13 | 29 | -4 | 24 | 17 | 18 | -4 | -5 | -19 | -24 | -7 | -13 | 5 |
9/11/08 16:24 | 9/10/08 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Med. | M.d | 67 | 10.19 | 33 | 7 | 5 | 142 | D | -24 | -33 | 74 | -16 | -19 | 2 | 0 | 3 | -4 | -5 | -7 | -13 | 5 | 30 |
9/11/08 16:24 | 9/10/08 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Med. | S.d | -173 | 26.23 | 33 | -7 | -4 | 142 | D | -24 | -33 | 74 | -16 | -19 | 2 | 0 | 3 | -4 | -5 | -7 | -13 | 5 | 30 |
9/4/08 16:14 | 9/3/08 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Med. | M.d | 67 | 10.19 | 33 | 7 | 5 | 142 | D | -24 | -33 | 55 | -9 | -20 | -9 | -3 | -4 | 3 | 5 | 20 | -13 | 9 | 39 |
9/4/08 16:14 | 9/3/08 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Med. | S.d | -171 | 25.86 | 33 | -7 | -4 | 142 | D | -24 | -33 | 55 | -9 | -20 | -9 | -3 | -4 | 3 | 5 | 20 | -13 | 9 | 39 |
8/28/08 13:19 | 8/27/08 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Med. | M.d | 67 | 10.19 | 33 | 7 | 5 | 142 | D | -24 | -25 | 47 | -5 | -17 | -7 | -2 | 0 | 1 | -5 | 25 | -15 | 12 | 38 |
8/28/08 13:19 | 8/27/08 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Med. | S.d | -179 | 27.02 | 33 | -7 | -4 | 142 | D | -24 | -25 | 47 | -5 | -17 | -7 | -2 | 0 | 1 | -5 | 25 | -15 | 12 | 38 |
8/21/08 13:52 | 8/20/08 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Med. | M.d | 67 | 10.19 | 33 | 7 | 5 | 142 | D | -20 | -30 | 48 | 1 | -21 | -24 | -10 | -8 | 2 | 3 | 11 | 0 | 26 | 38 |
8/21/08 13:52 | 8/20/08 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Med. | S.d | -182 | 27.57 | 33 | -7 | -4 | 142 | D | -20 | -30 | 48 | 1 | -21 | -24 | -10 | -8 | 2 | 3 | 11 | 0 | 26 | 38 |
6/23/08 11:21 | 6/19/08 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Med. | M.d | 130 | 15.76 | 33 | 8 | 6 | 142 | D | 7 | 24 | 34 | 86 | 24 | 17 | 4 | 0 | -5 | -3 | -6 | -12 | -13 | -1 |
5/22/08 09:24 | 5/20/08 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Med. | S.m | -22 | 27.62 | 33 | -1 | -1 | 134 | D | -14 | -17 | 4 | 47 | -1 | -2 | -6 | -6 | 4 | 9 | 28 | 1 | 1 | 11 |
12/12/07 11:22 | 12/11/07 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Medi | S | -12 | 25.62 | 33 | 0 | 0 | 124 | D | -3 | -42 | -8 | -38 | -21 | 2 | -1 | -3 | 0 | -1 | -10 | -39 | 27 | -1 |
11/19/07 14:50 | 11/16/07 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Medi | S | 0 | 25.82 | 33 | 0 | 0 | 124 | D | -1 | -42 | -19 | -30 | -30 | -22 | 4 | -2 | -2 | -8 | -3 | -30 | 7 | 4 |
8/8/07 10:24 | 8/6/07 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Medi | M.d | 351 | 11.42 | 33 | 31 | 33 | 124 | D | 141 | 17 | 14 | 25 | 43 | 29 | 16 | 14 | 2 | -7 | 7 | -36 | -49 | -16 |
8/8/07 10:24 | 8/6/07 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Medi | S.d | -1,075 | 35.00 | 33 | -31 | -20 | 124 | D | 141 | 17 | 14 | 25 | 43 | 29 | 16 | 14 | 2 | -7 | 7 | -36 | -49 | -16 |
5/21/07 15:21 | 5/17/07 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Medi | S | -25 | 31.95 | 33 | -1 | -1 | 124 | D | 138 | 1 | -26 | 3 | 0 | 2 | 3 | -1 | 0 | -3 | -13 | 17 | -17 | -13 |
5/8/07 14:52 | 5/7/07 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Medi | S.d | -994 | 30.59 | 33 | -33 | -21 | 126 | D | 215 | -15 | -24 | -6 | 9 | -4 | -3 | -1 | -1 | 0 | -5 | 18 | -5 | -13 |
5/8/07 14:52 | 5/7/07 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Medi | M.d | 200 | 12.22 | 33 | 16 | 15 | 126 | D | 215 | -15 | -24 | -6 | 9 | -4 | -3 | -1 | -1 | 0 | -5 | 18 | -5 | -13 |
2/1/07 12:42 | 1/31/07 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Medi | M.d | 23 | 15.34 | 33 | 2 | 1 | 142 | D | 252 | 2 | 5 | -13 | -9 | 0 | -2 | 1 | -2 | -6 | -17 | -13 | -8 | -42 |
2/1/07 12:42 | 1/31/07 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Medi | S.d | -53 | 35.46 | 33 | -2 | -1 | 142 | D | 252 | 2 | 5 | -13 | -9 | 0 | -2 | 1 | -2 | -6 | -17 | -13 | -8 | -42 |
1/26/07 15:26 | 1/24/07 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Med. | M.d | 23 | 15.34 | 33 | 2 | 1 | 142 | D | 244 | 4 | -2 | 4 | -15 | -5 | -9 | -3 | 0 | -1 | -10 | -10 | -6 | -45 |
1/26/07 15:26 | 1/24/07 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Med. | S.d | -54 | 36.20 | 33 | -2 | -1 | 142 | D | 244 | 4 | -2 | 4 | -15 | -5 | -9 | -3 | 0 | -1 | -10 | -10 | -6 | -45 |
1/18/07 15:16 | 1/17/07 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Medi | M.d | 23 | 15.34 | 33 | 2 | 1 | 110 | D | 265 | 12 | 13 | 5 | -14 | 1 | 6 | 5 | -1 | -4 | -17 | -16 | -23 | -37 |
1/18/07 15:16 | 1/17/07 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Medi | S.d | -57 | 38.29 | 33 | -2 | -1 | 110 | D | 265 | 12 | 13 | 5 | -14 | 1 | 6 | 5 | -1 | -4 | -17 | -16 | -23 | -37 |
1/11/07 15:46 | 1/10/07 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Medi | M.d | 23 | 15.34 | 33 | 2 | 1 | 110 | D | 237 | 7 | -1 | -5 | -18 | -8 | -7 | -1 | 2 | 6 | -9 | -11 | -17 | -37 |
1/11/07 15:46 | 1/10/07 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Medi | S.d | -53 | 35.00 | 33 | -2 | -1 | 110 | D | 237 | 7 | -1 | -5 | -18 | -8 | -7 | -1 | 2 | 6 | -9 | -11 | -17 | -37 |
1/4/07 16:26 | 1/3/07 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | SVP, Dru | M.d | 23 | 15.34 | 33 | 2 | 1 | 110 | D | 249 | 33 | 1 | 8 | -17 | -10 | -1 | -1 | -3 | -4 | -9 | -19 | -22 | -42 |
1/4/07 16:26 | 1/3/07 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | SVP, Dru | S.d | -56 | 37.28 | 33 | -2 | -1 | 110 | D | 249 | 33 | 1 | 8 | -17 | -10 | -1 | -1 | -3 | -4 | -9 | -19 | -22 | -42 |
12/28/06 12:34 | 12/27/06 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | SVP, Dru | M.d | 23 | 15.34 | 33 | 2 | 1 | 110 | D | 244 | 33 | 26 | 14 | -12 | -16 | -4 | 0 | 1 | -4 | -4 | -25 | -24 | -37 |
12/28/06 12:34 | 12/27/06 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | SVP, Dru | S.d | -56 | 37.56 | 33 | -2 | -1 | 110 | D | 244 | 33 | 26 | 14 | -12 | -16 | -4 | 0 | 1 | -4 | -4 | -25 | -24 | -37 |
12/21/06 14:28 | 12/20/06 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | SVP, Dru | M.d | 23 | 15.34 | 33 | 2 | 1 | 110 | D | 242 | 37 | 21 | 14 | -11 | -15 | -9 | -4 | 0 | 1 | -3 | -25 | -30 | -33 |
12/21/06 14:28 | 12/20/06 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | SVP, Dru | S.d | -57 | 37.78 | 33 | -2 | -1 | 110 | D | 242 | 37 | 21 | 14 | -11 | -15 | -9 | -4 | 0 | 1 | -3 | -25 | -30 | -33 |
12/15/06 11:31 | 12/13/06 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Medi | M.ad | 23 | 15.34 | 33 | 2 | 1 | 110 | D | 238 | 42 | 17 | 17 | -2 | -14 | -13 | -6 | 1 | -3 | -4 | -28 | -30 | -37 |
12/15/06 11:31 | 12/13/06 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Medi | S.ad | -76 | 38.62 | 33 | -2 | -2 | 110 | D | 238 | 42 | 17 | 17 | -2 | -14 | -13 | -6 | 1 | -3 | -4 | -28 | -30 | -37 |
12/14/06 10:36 | 12/13/06 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Medi | S | -76 | 38.62 | 33 | -2 | -2 | 108 | D | 237 | 42 | 17 | 15 | -3 | -14 | -12 | -10 | 0 | -3 | -2 | -29 | -29 | -36 |
12/7/06 12:56 | 12/6/06 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Medi | M.d | 23 | 15.34 | 33 | 2 | 1 | 110 | D | 323 | 80 | 39 | 28 | 32 | 1 | 4 | 1 | -2 | -13 | -24 | -32 | -39 | -43 |
12/7/06 12:56 | 12/6/06 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Medi | S.d | -67 | 44.69 | 33 | -2 | -1 | 110 | D | 323 | 80 | 39 | 28 | 32 | 1 | 4 | 1 | -2 | -13 | -24 | -32 | -39 | -43 |
11/30/06 15:01 | 11/29/06 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Medi | M.d | 23 | 15.34 | 33 | 2 | 1 | 110 | D | 323 | 78 | 31 | 28 | 24 | 7 | 1 | 0 | -1 | -1 | -17 | -36 | -34 | -43 |
11/30/06 15:01 | 11/29/06 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Medi | S.d | -66 | 44.21 | 33 | -2 | -1 | 110 | D | 323 | 78 | 31 | 28 | 24 | 7 | 1 | 0 | -1 | -1 | -17 | -36 | -34 | -43 |
11/27/06 10:54 | 11/22/06 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Med. | M.d | 28 | 18.47 | 33 | 2 | 1 | 111 | D | 313 | 71 | 33 | 27 | 24 | 13 | 5 | 0 | -4 | -2 | -17 | -32 | -33 | -46 |
11/27/06 10:54 | 11/22/06 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Med. | S.d | -67 | 44.36 | 33 | -2 | -1 | 111 | D | 313 | 71 | 33 | 27 | 24 | 13 | 5 | 0 | -4 | -2 | -17 | -32 | -33 | -46 |
11/16/06 16:23 | 11/15/06 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Med. | M.d | 28 | 18.47 | 33 | 2 | 1 | 110 | D | 294 | 69 | 50 | 34 | 19 | 27 | 9 | 4 | 0 | 1 | -13 | -30 | -30 | -43 |
11/16/06 16:23 | 11/15/06 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Med. | S.d | -96 | 43.70 | 33 | -2 | -2 | 110 | D | 294 | 69 | 50 | 34 | 19 | 27 | 9 | 4 | 0 | 1 | -13 | -30 | -30 | -43 |
11/9/06 14:09 | 11/8/06 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Med. | M.d | 28 | 18.47 | 33 | 2 | 1 | 110 | D | 266 | 71 | 19 | 38 | 26 | 16 | 5 | 6 | -2 | 5 | 3 | -24 | -27 | -39 |
11/9/06 14:09 | 11/8/06 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Med. | S.d | -62 | 41.49 | 33 | -2 | -1 | 110 | D | 266 | 71 | 19 | 38 | 26 | 16 | 5 | 6 | -2 | 5 | 3 | -24 | -27 | -39 |
11/2/06 16:02 | 11/1/06 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Med. | M.d | 55 | 18.47 | 33 | 3 | 3 | 110 | D | 267 | 70 | 12 | 22 | 21 | 10 | 18 | -2 | 0 | 6 | 11 | -18 | -23 | -27 |
11/2/06 16:02 | 11/1/06 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Med. | S.d | -121 | 40.33 | 33 | -3 | -3 | 110 | D | 267 | 70 | 12 | 22 | 21 | 10 | 18 | -2 | 0 | 6 | 11 | -18 | -23 | -27 |
10/19/06 13:49 | 10/18/06 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Med. | M.d | 28 | 18.47 | 33 | 2 | 1 | 110 | D | 253 | 60 | -8 | 3 | 4 | 8 | -3 | 0 | 0 | -7 | 23 | -1 | -13 | -15 |
10/19/06 13:49 | 10/18/06 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Med. | S.d | -54 | 36.26 | 33 | -2 | -1 | 110 | D | 253 | 60 | -8 | 3 | 4 | 8 | -3 | 0 | 0 | -7 | 23 | -1 | -13 | -15 |
10/12/06 13:54 | 10/11/06 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Med. | M.d | 139 | 18.47 | 33 | 8 | 7 | 110 | D | 239 | 71 | 2 | 3 | 2 | 9 | 5 | -3 | 1 | 1 | 15 | 6 | -16 | 0 |
10/12/06 13:54 | 10/11/06 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Med. | S.d | -265 | 35.35 | 33 | -8 | -6 | 110 | D | 239 | 71 | 2 | 3 | 2 | 9 | 5 | -3 | 1 | 1 | 15 | 6 | -16 | 0 |
9/7/06 13:59 | 9/6/06 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Med. | M.d | 28 | 18.47 | 31 | 2 | 1 | 110 | D | 237 | 93 | -14 | 10 | -2 | 8 | -2 | 1 | 0 | -1 | 6 | 28 | -16 | 14 |
9/7/06 13:59 | 9/6/06 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Med. | S.d | -53 | 35.59 | 31 | -2 | -1 | 110 | D | 237 | 93 | -14 | 10 | -2 | 8 | -2 | 1 | 0 | -1 | 6 | 28 | -16 | 14 |
8/31/06 14:05 | 8/30/06 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Med. | M.d | 139 | 18.47 | 30 | 8 | 7 | 110 | D | 260 | 96 | -20 | 2 | 0 | 15 | 8 | -1 | -1 | -1 | -4 | 28 | -17 | 11 |
8/31/06 14:05 | 8/30/06 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | EVP,Med. | S.d | -263 | 35.00 | 30 | -8 | -6 | 110 | D | 260 | 96 | -20 | 2 | 0 | 15 | 8 | -1 | -1 | -1 | -4 | 28 | -17 | 11 |
12/15/05 14:55 | 12/14/05 | VRTX | Vertex Pharmaceuticals Inc / Ma | MA | Health | Drug | Pharmaceutical Preparations | Alam John J | MA | O | SVP, Dru | S | -143 | 27.47 | 33 | -5 | -6 | 89 | D | 206 | 139 | 96 | 45 | 14 | 4 | 9 | 3 | 1 | 2 | 23 | 48 | 21 | 42 |