Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	Title	#f	T	TVal	Price	Qty	oc	Own	H
10/17/25 21:05	10/15/25	NTRA	Natera, Inc.	DE	Health	Health	Medical Laboratories	Sheena Jonathan	TX	DH	CO-FOUND	26	S.dm	-24,417	147.93	-165		442	M
10/17/25 21:00	10/15/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Venker Eric	X0	O	P,Immuno	18	S.dm	-92,095	13.36	-6,893		1,654	D
10/17/25 20:44	10/17/25	ARTV	Artiva Biotherapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Aslan Fred	CA	DO	P,CEO	2	S	-223	4.36	-51		382	D
10/17/25 19:55	10/15/25	BLFS	Biolife Solutions Inc	DE	Health	ElcMd	Electromedical & Electrothera	Casdin Partners Master Fund, L.P.	NY	T		4	S	-68,710	24.99	-2,750		7,707	I
10/17/25 19:29	10/17/25	LXEO	Lexeo Therapeutics, Inc.		Health	BioPrd	Biological Products, (No Diag	See Tai Sandi	NY	O	Chief De	4	S	-44	7.21	-6		66	D
10/17/25 19:28	10/17/25	LXEO	Lexeo Therapeutics, Inc.		Health	BioPrd	Biological Products, (No Diag	Robertson Jenny	NY	O	GC	4	S	-45	6.69	-7		69	D
10/17/25 19:28	10/17/25	LXEO	Lexeo Therapeutics, Inc.		Health	BioPrd	Biological Products, (No Diag	Otero Jose Manuel	NY	O	Chief Te	2	S	-32	6.49	-5		64	D
10/17/25 19:26	10/17/25	LXEO	Lexeo Therapeutics, Inc.		Health	BioPrd	Biological Products, (No Diag	Adler Eric	NY	O	Chief Me	4	S	-45	6.51	-7		73	D
10/17/25 19:26	10/17/25	LXEO	Lexeo Therapeutics, Inc.		Health	BioPrd	Biological Products, (No Diag	Townsend Richard Nolan	NY	DO	CEO	12	S.dm	-1,361	13.29	-102		242	D
10/17/25 18:33	10/15/25	VOR	Vor Biopharma Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Reprogrammed Interchange LLC	CA	T		11	S.m	-26,547	4.01	-6,628		38,303	D
10/17/25 18:03	8/9/24	VOR	Vor Biopharma Inc.		Health	BioPrd	Biological Products, (No Diag	Ra Capital Management, L.P.	MA	DT		2	S.m	-17,514	4.39	-3,989		316	I
10/17/25 17:53	10/15/25	KROS	Keros Therapeutics, Inc.		Health	Drug	Pharmaceutical Preparations	Pontifax Management 4 G.P. (2015) Ltd.	L3	T		1	S	-84,975	17.75	-4,787	-100	11	I
10/17/25 17:11	8/26/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cloonan Michael	MA	DO	P,CEO	4	S.dm	-2,709	27.04	-100		547	D
10/17/25 16:41	10/15/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bitterman Kevin	MA	D		8	S.m	-19,663	72.70	-270		1,148	I
10/17/25 16:39	10/10/25	MLSS	Milestone Scientific Inc.	DE	Health	Orthop	Orthopedic, Prosthetic & Surg	Bp4 S.R.L.	L6	T		14	S.m	-358	0.7516	-477		9,655	D
10/17/25 16:32	8/15/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Porter James Richard	MA	DO	P,CEO	14	S.d	-29,729	80.72	-368		249	D
10/17/25 16:32	10/15/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Miller Deborah Ann	MA	O	GC	9	S.dm	-6,298	86.32	-73		49	D
10/17/25 16:31	8/7/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pelish Henry E.	MA	O	Chief Sc	10	S.dm	-8,707	88.92	-98		66	D
10/17/25 16:31	10/15/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Balcom Alexandra	MA	O	CFO	13	S.dm	-16,560	85.68	-193		62	D
10/17/25 16:28	10/16/25	SDGR	Schrodinger, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dugan Margaret	NY	O	Chief Me	2	S	-57	19.35	-3		25	D
10/17/25 16:27	10/15/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McCarthy Teresa	CA	O	CHRO	12	S.d	-7,828	41.22	-190		105	D
10/17/25 16:15	10/15/25	VIR	Vir Biotechnology, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Svf Endurance (Cayman) Ltd	E9	T		4	S.m	-7,870	5.86	-1,344		16,160	I
10/17/25 16:15	10/16/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Watson David O.	MA	O	GC	12	S	-1,743	26.11	-67		228	D
10/17/25 16:10	10/16/25	PRAX	Praxis Precision Medicines, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Adage Capital Management, L.P.	MA	T		1	S	-33,198	105.76	-314		4,422	I
10/17/25 16:01	10/15/25	INCY	Incyte Corp	DE	Health	Biolab	Commercial Physical & Biologi	Denton Sheila A.	DE	O	EVP,GC	11	S.dm	-2,052	75.16	-27		33	D
10/17/25 15:08	8/13/25	MRAI	Marpai, Inc.	DE	Health	Health	Misc Health & Allied Services	Intelligent Fanatics Capital Management LLC	PA	T		1	S.m	-271	1.44	-188		3,541	M
10/17/25 14:01	10/15/25	AQST	Aquestive Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jung Cassie	NJ	O	COO	3	S.d	-785	6.05	-130		285	D
10/17/25 14:01	10/15/25	AQST	Aquestive Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kraus Carl N	NJ	O	Chief Me	1	S	-142	7.00	-20		282	D
10/17/25 14:00	10/15/25	AQST	Aquestive Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Boyd Peter E.	NJ	O	See Rema	3	S	-213	6.07	-35		288	D
10/16/25 21:35	10/15/25	GILD	Gilead Sciences, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Dickinson Andrew D	CA	O	CFO	15	S.d	-56,571	97.55	-580		173	D
10/16/25 21:28	10/15/25	GILD	Gilead Sciences, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Mercier Johanna	CA	O	Chief Co	10	S.d	-11,752	100.14	-117		121	D
10/16/25 20:16	10/16/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Swayze Eric	CA	O	EVP Rese	9	S.adm	-3,247	57.08	-57		48	I
10/16/25 20:16	9/9/24	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Parshall B Lynne	CA	D		11	S.d	-3,779	53.98	-70		107	D
10/16/25 20:16	10/15/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Devers Shannon L.	CA	O	EVP,Chie	3	S.dm	-863	58.77	-15		17	D
10/16/25 20:15	10/14/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Birchler Brian	CA	O	EVP,Corp	3	S.dm	-1,920	64.04	-30		57	D
10/16/25 18:18	5/2/25	GRAL	Grail, Inc.		Health	Health	Medical Laboratories	Ragusa Robert P	CA	DO	CEO	6	S	-5,937	24.64	-241		836	D
10/16/25 18:17	8/19/25	GRAL	Grail, Inc.		Health	Health	Medical Laboratories	Ofman Joshua J.	CA	O	P	11	S.m	-10,924	42.56	-257		562	D
10/16/25 18:00	10/14/25	BGMS	Bio Green Med Solution, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ong Yee Lung	N8	T		1	S	-815	6.00	-136		269	D
10/16/25 17:44	10/16/25	AURA	Aura Biosciences, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Plavsic Mark	MA	O	CTO	3	S	-167	7.68	-22		209	D
10/16/25 17:05	9/2/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Blum Robert I	CA	DO	P,CEO	32	S.d	-13,867	47.11	-294		443	D
10/16/25 16:41	10/15/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cohlhepp Ryan	MA	DO	P,COO	2	S.dm	-1,139	18.08	-63		203	D
10/16/25 16:35	10/14/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Tessari Eben	X0	O	COO	20	S.dm	-18,604	30.86	-603		120	D
10/16/25 16:30	8/26/24	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	48	S.dm	-117,568	353.83	-332		647	D
10/16/25 16:30	10/15/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bredt David	MA	O	Chief Sc	8	S	-1,020	14.99	-68		469	D
10/16/25 16:30	9/4/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ceesay Abraham	MA	DO	CEO	3	S	-2,357	26.28	-90		722	D
10/16/25 16:21	10/7/25	EBS	Emergent Biosolutions Inc.	DE	Health	Drug	Pharmaceutical Preparations	Glessner Coleen	MD	O	EVP,Qual	1	S	-306	10.00	-31		144	D
10/16/25 16:15	10/14/25	CDRE	Cadre Holdings, Inc.	DE	Health	Orthop	Orthopedic, Prosthetic & Surg	Williams Brad	FL	O	P	3	S	-1,174	35.30	-33		114	D
10/16/25 16:15	7/9/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Seshadri Vishwas	OH	DO	CEO	5	S.m	-1,105	5.83	-190		1,355	D
10/16/25 16:13	8/15/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Hussain Iqbal J	X0	O	GC	12	S.dm	-3,112	17.51	-178		131	D
10/16/25 16:01	10/14/25	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Militello John	NJ	O	See Rema	12	S.m	-259	5.57	-46		67	D
10/15/25 20:56	10/13/25	LVTX	Lava Therapeutics Nv	P7	Health	Drug	Pharmaceutical Preparations	Cooperatieve Gilde Healthcare IV U.A.	P7	T		2	S.m	-917	1.52	-602		5,294	D
10/15/25 20:12	10/10/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dunlop A. Sinclair	MA	D		5	S	-4,946	29.57	-167		302	M
10/15/25 20:07	9/12/25	BYSI	Beyondspring Inc.		Health	Drug	Pharmaceutical Preparations	Decheng Capital China Life Sciences Usd Fund Iii, L.P.	CA	T		16	S.m	-1,792	2.48	-723		4,488	I
10/15/25 19:28	1/7/25	ACLX	Arcellx, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Gilson Michelle	CA	O	CFO	10	S.dm	-8,108	76.93	-105		28	D
10/15/25 19:04	10/13/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Levy Adam Scott	PA	O	CFO,Secr	8	S.m	-3,453	14.69	-235		255	D
10/15/25 19:04	10/13/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Congleton Jon	PA	DO	CEO	8	S.m	-3,160	14.51	-218		976	D
10/15/25 19:04	10/15/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rodman David Malcom	PA	O	Chief Me	11	S.d	-3,018	18.25	-165		141	D
10/15/25 18:47	10/15/25	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	Hopkinson Craig C.	MA	O	EVP R,D,	8	S.dm	-20,144	32.84	-613		99	D
10/15/25 18:33	10/10/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Booth Bruce	MA	D		5	S.m	-28,090	34.93	-804		4,417	I
10/15/25 18:31	10/10/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Swisher Daniel N Jr	CA	D		15	S.d	-1,922	62.09	-31	-100	0	D
10/15/25 18:00	10/13/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mazumdar Claire	MA	DO	CEO	1	S.dm	-467	18.88	-25		310	D
10/15/25 17:35	8/18/25	CRSP	Crispr Therapeutics AG	V8	Health	BioPrd	Biological Products, (No Diag	Kulkarni Samarth	MA	DO	CEO	9	S.dm	-6,787	53.02	-128		312	D
10/15/25 17:35	10/14/25	CRSP	Crispr Therapeutics AG	V8	Health	BioPrd	Biological Products, (No Diag	Kasinger James R.	MA	O	GC,Secre	5	S.dm	-1,042	49.96	-21		83	D
10/15/25 17:28	10/15/25	KYMR	Kymera Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Gollob Jared	MA	O	Chief Me	4	S.dm	-5,824	53.91	-108		120	D
10/15/25 17:09	10/13/25	RVMD	Revolution Medicines, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Kelsey Stephen Michael	CA	O	See Rema	14	S.dm	-12,526	45.45	-276		293	D
10/15/25 16:36	10/13/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Schundler Russell	NC	O	GC	13	S.d	-857	15.17	-56		597	D
10/15/25 16:34	10/13/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Kaseta Michael	NC	O	CFO,COO	15	S.d	-2,392	17.91	-134		412	D
10/15/25 16:34	10/13/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Moomaw Scott	NC	O	Chief Co	13	S.d	-2,539	24.25	-105		225	D
10/15/25 16:33	10/13/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Saggar Rajeev	NC	O	Chief Me	13	S.d	-1,205	18.90	-64		273	D
10/15/25 16:32	10/13/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Boyle Dana	NC	O	Chief Ac	4	S	-75	19.89	-4		187	D
10/15/25 16:32	10/6/25	SPRB	Spruce Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Parkman Healthcare Partners LLC	CT	T		2	S	-10	19.14	-1		1	I
10/15/25 16:31	9/2/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Jeffs Roger	NC	DO	CEO	11	S.dm	-15,591	61.36	-254		2,764	D
10/15/25 16:31	10/13/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Adair Jason	NC	O	Chief Bu	19	S.dm	-1,115	21.58	-52		194	D
10/15/25 16:30	10/13/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Benkowitz Michael	MD	O	P,COO	28	S.dm	-151,596	385.98	-393		3	I
10/15/25 16:30	10/13/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Krepp Sarah	NC	O	Chief Hu	3	S	-84	18.33	-5		143	D
10/15/25 16:15	9/3/25	CGON	Cg Oncology, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Post Leonard E	CA	D		14	S.d	-613	28.74	-21		30	D
10/15/25 13:24	10/15/25	KROS	Keros Therapeutics, Inc.		Health	Drug	Pharmaceutical Preparations	Adar1 Capital Management, LLC	TX	T		1	S	-95,659	17.75	-5,389	-100	0	I
10/14/25 20:11	10/10/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cheng Andrew	CA	DO	P,CEO	18	S.dm	-22,840	40.75	-560		716	D
10/14/25 19:49	10/13/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Cook Meredith	MN	O	SVP,GC,S	17	S	-390	67.76	-6		82	D
10/14/25 18:00	10/10/25	BGMS	Bio Green Med Solution, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fitters Diversified Berhad	N8	T		2	S	-1,022	5.28	-193		557	D
10/14/25 17:30	9/11/25	BLFS	Biolife Solutions Inc	DE	Health	ElcMd	Electromedical & Electrothera	Wichterman Troy	WA	O	CFO	16	S.m	-951	23.36	-41		189	D
10/14/25 17:30	9/11/25	BLFS	Biolife Solutions Inc	DE	Health	ElcMd	Electromedical & Electrothera	Berard Todd	WA	O	CMO	18	S.m	-814	23.13	-35		136	D
10/14/25 17:30	10/9/25	BLFS	Biolife Solutions Inc	DE	Health	ElcMd	Electromedical & Electrothera	Mathew Aby J.	WA	O	EVP,Chie	20	S.dm	-2,853	23.31	-122		354	D
10/14/25 17:30	9/15/25	BLFS	Biolife Solutions Inc	DE	Health	ElcMd	Electromedical & Electrothera	Aebersold Sarah	WA	O	CHRO	20	S.m	-805	24.46	-33		80	D
10/14/25 17:30	9/11/25	BLFS	Biolife Solutions Inc	DE	Health	ElcMd	Electromedical & Electrothera	Foster Karen A.	WA	O	Chief Qu	16	S.m	-324	23.59	-14		196	D
10/14/25 16:33	10/10/25	CLPT	Clearpoint Neuro, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Burnett Joseph	CA	DO	CEO,P	2	S	-996	20.88	-48		269	I
10/14/25 16:31	10/9/25	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	Bunn Paul A.	MA	D		1	S	-75	9.06	-8		8	D
10/14/25 16:17	10/10/25	HIMS	Hims & Hers Health, Inc.	DE	Health	Health	Offices & Clinics of Doctors	Chi Michael	CA	O	Chief Co	40	S.dm	-34,373	24.95	-1,378		311	D
10/14/25 16:17	10/13/25	HIMS	Hims & Hers Health, Inc.	DE	Health	Health	Offices & Clinics of Doctors	Boughton Soleil	CA	O	GC	33	S.dm	-15,263	28.06	-544		177	D
10/14/25 16:10	7/7/25	FENC	Fennec Pharmaceuticals Inc.	A1	Health	BioPrd	Biological Products, (No Diag	Rallis Chris A	NC	D		6	S.d	-87	6.66	-13		57	D
10/14/25 16:05	10/9/25	CVKD	Cadrenal Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Szot Matthew K	FL	O	CFO	5	S.m	-278	14.03	-20		31	D
10/14/25 16:05	10/9/25	CVKD	Cadrenal Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pham Quang X	FL	DOT	CEO,CB	5	S.m	-278	14.05	-20		413	D
10/14/25 16:05	10/13/25	IRMD	Iradimed Corp	DE	Health	MdEq	Surgical & Medical Instrument	Susi Roger E.	FL	DOT	CEO,P,CB	5	S	-1,785	71.41	-25		4,583	I
10/14/25 16:04	10/9/25	FDMT	4D Molecular Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Bizily Scott	CA	O	GC	8	S.d	-289	18.55	-16		8	D
10/14/25 16:01	12/16/24	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	Waddill William D.	CA	D		8	S.dm	-2,815	50.73	-55		54	D
10/14/25 16:00	7/24/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	Lilly Endowment Inc	IN	T		41	S.e	-3,347,312	860.38	-3,890		98,402	D
10/14/25 13:16	8/18/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	Moreadith Randall	AL	O	Chief Sc	11	S.dm	-641	6.16	-104	-100	0	D
10/14/25 12:15	10/13/25	RARE	Ultragenyx Pharmaceutical Inc.	DE	Health	Drug	Pharmaceutical Preparations	Horn Howard	CA	O	CFO	3	S	-716	41.66	-17		106	D
10/14/25 07:55	11/6/24	BPMC	Blueprint Medicines Corp	DE	Health	Drug	Pharmaceutical Preparations	Albers Jeffrey W.	MA	D		13	S.d	-8,500	83.77	-101		192	I
10/10/25 19:17	10/10/25	ZVRA	Zevra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McFarlane Neil F.	FL	DO	P,CEO	2	S.dm	-938	8.43	-111		222	D
10/10/25 18:38	9/10/25	RGNX	Regenxbio Inc.		Health	BioPrd	Biological Products, (No Diag	Simpson Curran	MD	DO	CEO	5	S	-563	12.27	-46		245	D
10/10/25 18:17	9/12/25	BGMS	Bio Green Med Solution, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kua Khai Loon	N8	T		2	S.m	-400	6.04	-66		385	D
10/10/25 18:03	10/10/25	RXRX	Recursion Pharmaceuticals, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Gibson Christopher	UT	DO	CEO	16	S.dm	-10,035	5.95	-1,687		1,273	D
10/10/25 17:40	9/4/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kumar Neil	CA	DO	CEO	13	S.dm	-52,350	38.53	-1,359		6,906	I
10/10/25 17:33	10/9/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Khattar Jack A.	MD	DO	P,CEO	15	S.dm	-27,668	42.17	-656		2,212	D
10/10/25 17:27	10/9/25	EXAS	Exact Sciences Corp	DE	Health	Health	Medical Laboratories	Herriott James	WI	O	SVP,GC,S	1	S	-90	60.00	-2		16	D
10/10/25 17:25	10/9/25	EXAS	Exact Sciences Corp	DE	Health	Health	Medical Laboratories	Doyle James Edward	WI	D		2	S	-182	52.34	-3		60	D
10/10/25 17:23	10/9/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Raben David	MA	O	Chief Me	1	S.d	-406	18.45	-22		35	D
10/10/25 17:22	10/9/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hyep Ivan	MA	O	CFO	2	S.dm	-670	18.21	-37		145	D
10/10/25 16:56	10/8/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Lee Chan Henry	V8	O	SVP,GC	11	S.d	-12,008	310.97	-39		278	D
10/10/25 16:30	10/8/25	ALZN	Alzamend Neuro, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ault Milton C III	NV	D		11	S.dm	-2,218	2.45	-906		124	I
10/10/25 16:21	10/9/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Newhall Charles W III	MD	D		5	S.d	-1,927	46.21	-42		134	D
10/10/25 16:18	10/8/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Scadden David	MA	D		5	S.d	-89	40.66	-2		18	D
10/10/25 16:15	10/9/25	CGON	Cg Oncology, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Mulay James	CA	D		4	S.dm	-2,496	36.52	-68	-100	0	D
10/10/25 16:12	10/8/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kaye Edward M. Md	MA	D		11	S.dm	-4,841	24.51	-198		183	D
10/10/25 16:05	10/8/25	TWST	Twist Bioscience Corp	DE	Health	BioPrd	Biological Products, (No Diag	Laponis Adam	CA	O	CFO	11	S.m	-1,254	38.56	-33		110	D
10/10/25 16:03	10/8/25	IMVT	Immunovant, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Geffner Michael	NY	O	Chief Me	7	S	-372	22.56	-16		225	D
10/10/25 16:01	10/8/25	IMVT	Immunovant, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Stout Jay S	NY	O	CTO	7	S	-342	21.96	-16		209	D
10/10/25 16:01	10/8/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	Anderman Todd	MA	O	GC	1	S	-137	12.34	-11		88	D
10/9/25 18:58	9/8/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rolph Timothy	CA	O	Chief Sc	19	S.dm	-9,382	49.10	-191		198	D
10/9/25 17:51	10/7/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Guyer William	CA	O	Chief De	17	S.dm	-14,050	63.86	-220		6	D
10/9/25 17:31	10/7/25	FENC	Fennec Pharmaceuticals Inc.	A1	Health	BioPrd	Biological Products, (No Diag	Southpoint Capital Advisors LP	NY	T		1	S.m	-636	9.48	-67		4,010	I
10/9/25 17:21	10/7/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Patel Anish	CO	O	COO	13	S.dm	-3,173	22.63	-140		394	I
10/9/25 16:41	10/7/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Viking Global Investors LP	CT	T		3	S	-272,277	39.37	-6,916		22,158	I
10/9/25 16:22	8/19/25	HOOK	Hookipa Pharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	Peters Malte	NY	DO	CEO	2	S	-48	0.8745	-54		80	D
10/9/25 13:37	10/8/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Degnan Chris	NJ	O	CFO	1	S.d	-37	16.85	-2		2	D
10/9/25 11:03	5/7/25	RMD	Resmed Inc	DE	Health	MdEq	Surgical & Medical Instrument	Farrell Michael J.	CA	O	CEO	16	S.d	-38,414	236.86	-162		470	D
10/8/25 21:08	10/6/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tabuteau Herriot	NY	DOT	CEO	2	S.dm	-12,780	118.04	-108		7,352	D
10/8/25 20:12	10/6/25	SGHT	Sight Sciences, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Taylor Brenton	CA	O	EVP,Oper	1	S	-2	3.37	-1	0	185	D
10/8/25 19:48	10/1/25	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hunter Heather	MI	O	SVP,COO	1	S	-3	1.19	-3		135	D
10/8/25 19:08	10/6/25	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jarrett Jennifer	CA	O	COO	1	S.dm	-750	14.92	-50		214	D
10/8/25 18:37	10/6/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	O'Neil Patrick R.	CA	O	EVP CLO,	11	S.adm	-14,432	61.64	-234		64	D
10/8/25 18:36	10/6/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Monia Brett P	CA	DO	CEO	11	S.ad	-17,851	51.30	-348		220	D
10/8/25 18:36	10/6/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Baroldi Joseph	CA	O	EVP,Chie	7	S.d	-4,094	58.50	-70		35	D
10/8/25 17:37	10/6/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Piscitelli Dominic	CA	O	CFO	7	S.dm	-850	10.65	-80		107	D
10/8/25 17:35	10/6/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chacko Jacob	CA	DO	P,CEO	4	S.dm	-3,069	11.17	-275		779	D
10/8/25 16:35	8/7/24	SERA	Sera Prognostics, Inc.	DE	Health	Health	Medical Laboratories	Harrison Robert Gardner	UT	O	CIO	15	S.dm	-332	4.84	-69		136	D
10/8/25 16:34	10/6/25	STE	Steris Plc	L2	Health	Orthop	Orthopedic, Prosthetic & Surg	Carestio Daniel A	L2	DO	P,CEO	2	S	-4,314	242.55	-18		51	D
10/8/25 16:16	10/7/25	CARM	Carisma Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Klichinsky Michael	PA	O	Chief Sc	2	S.dm	-139	0.2565	-541	-100	0	D
10/8/25 16:10	8/5/25	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	Taiwan Carbon Nano Technology Corp	F5	T		6	S.m	-167	1.94	-86		5,471	D
10/8/25 16:05	10/6/25	TWST	Twist Bioscience Corp	DE	Health	BioPrd	Biological Products, (No Diag	Leproust Emily M.	CA	DO	CEO	30	S.d	-5,652	39.57	-143		675	D
10/8/25 16:05	10/6/25	TWST	Twist Bioscience Corp	DE	Health	BioPrd	Biological Products, (No Diag	Werner Robert F.	CA	O	Chief Ac	21	S.m	-466	38.29	-12		53	D
10/8/25 16:05	10/6/25	TWST	Twist Bioscience Corp	DE	Health	BioPrd	Biological Products, (No Diag	Green Paula	CA	O	SVP of H	30	S	-1,629	39.62	-41		134	D
10/8/25 16:05	10/6/25	TWST	Twist Bioscience Corp	DE	Health	BioPrd	Biological Products, (No Diag	Finn Patrick John	CA	O	P,COO	24	S	-4,069	38.42	-106		274	D
10/8/25 16:05	10/6/25	TWST	Twist Bioscience Corp	DE	Health	BioPrd	Biological Products, (No Diag	Cho Dennis	CA	O	See Rema	37	S	-1,034	38.63	-27		114	D
10/7/25 21:49	10/7/25	MGTX	Meiragtx Holdings Plc		Health	BioPrd	Biological Products, (No Diag	Forbes Alexandria	NY	DO	P,CEO	4	S.dm	-1,336	7.03	-190		1,409	D
10/7/25 19:18	10/2/25	PLSE	Pulse Biosciences, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Danahy Kevin Patrick	CA	O	Chief Co	2	S.dm	-462	18.50	-25		43	D
10/7/25 18:29	10/3/25	CBLL	Ceribell, Inc.	DE	Health	ElcMd	Electromedical & Electrothera	Woo Raymond	CA	O	CTO	2	S.d	-274	12.33	-22		168	D
10/7/25 17:18	10/6/25	AXGN	Axogen, Inc.	MN	Health	ElcMd	Electromedical & Electrothera	Burke William P. Mr.	FL	D		3	S.m	-641	17.31	-37		24	D
10/7/25 17:08	9/9/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Malik Fady Ibraham	CA	O	EVP Rese	36	S.d	-7,762	50.12	-155		141	D
10/7/25 16:47	10/3/25	HIMS	Hims & Hers Health, Inc.	DE	Health	Health	Offices & Clinics of Doctors	Okupe Oluyemi	CA	O	CFO	29	S.d	-39,227	34.29	-1,144		211	D
10/7/25 16:30	10/3/25	VYGR	Voyager Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Jorgensen Nathan D.	MA	O	CFO	1	S	-37	4.78	-8		124	D
10/7/25 16:27	10/6/25	VCYT	Veracyte, Inc.	DE	Health	Health	Medical Laboratories	Febbo Phillip G.	CA	O	Chief Sc	3	S	-742	36.52	-20		92	D
10/7/25 16:26	10/3/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Allan Jonathan	MA	O	GC,Corp	7	S.dm	-1,277	17.01	-75		35	D
10/7/25 16:15	10/3/25	BBNX	Beta Bionics, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Feider Stephen	CA	O	CFO	8	S.d	-856	19.92	-43		46	D
10/7/25 16:11	10/3/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mosbrooker Eric	CA	O	Chief Co	3	S.d	-6,370	44.26	-144		55	D
10/6/25 20:00	6/13/25	NXGL	Nexgel, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Henry Scott Robert	PA	D		9	S.m	-105	2.85	-37		145	D
10/6/25 20:00	8/28/25	NXGL	Nexgel, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Levy Adam R.	PA	DO	CEO	10	S.dm	-94	2.94	-32		769	D
10/6/25 18:22	10/6/25	FENC	Fennec Pharmaceuticals Inc.	A1	Health	BioPrd	Biological Products, (No Diag	Raykov Rosty	NC	D		19	S	-953	7.13	-134		187	D
10/6/25 18:10	10/2/25	SIBN	Si-Bone, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Pisetsky Michael A.	CA	O	SVP,Ops,	5	S	-266	16.45	-16		265	D
10/6/25 18:10	10/2/25	SIBN	Si-Bone, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Maheshwari Anshul	CA	O	CFO	15	S.m	-1,622	16.98	-96		274	D
10/6/25 18:09	8/18/25	SIBN	Si-Bone, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Recupero Anthony J	CA	O	P,Commer	11	S.m	-778	15.08	-52		288	D
10/6/25 17:13	10/2/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	Kaiser Peter	MA	O	Chief De	5	S	-211	9.79	-22		213	D
10/6/25 17:10	10/2/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	Heier Jeffrey S.	MA	O	Chief Sc	5	S	-222	9.83	-23		269	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Lee Kevin	X0	DO	CEO	6	S.dm	-437	12.42	-35		492	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Skynner Michael	X0	O	CTO	6	S.dm	-143	12.34	-12		124	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Milnes Alistair	X0	O	COO	6	S.dm	-169	12.19	-14		100	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Hannay Michael Charles Ferguson	X0	O	CHIEF PR	6	S.dm	-57	11.97	-5		55	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Young Alethia	X0	O	CFO	4	S.d	-27	11.73	-2		46	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Thompson Travis Alvin	X0	O	Chief Ac	7	S.dm	-238	19.68	-12		32	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Swanton Robert Charles	X0	D		1	S	-1	8.55	0		15	D
10/6/25 16:15	9/5/25	SERA	Sera Prognostics, Inc.	DE	Health	Health	Medical Laboratories	Mirza Mansoor Raza	UT	D		15	S.d	-8	4.22	-2		59	D
10/6/25 16:11	10/2/25	CSTL	Castle Biosciences Inc	DE	Health	Health	Medical Laboratories	Maetzold Derek J	TX	DO	P,Chief	28	S.dm	-5,349	24.30	-220		437	D
10/6/25 15:15	5/19/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Edwards Larry Todd	CA	O	See Rema	4	S	-260	14.56	-18		183	D
10/3/25 21:58	7/8/25	ELTP	Elite Pharmaceuticals Inc /Nv/	NJ	Health	Drug	Pharmaceutical Preparations	Plassche Douglas	NJ	O	EVP Oper	3	S.m	-1,177	0.5517	-2,134		3,500	D
10/3/25 21:27	2/3/25	JAZZ	Jazz Pharmaceuticals Plc	L2	Health	Drug	Pharmaceutical Preparations	Cozadd Bruce C	L2	D		12	S.m	-3,876	129.21	-30		464	D
10/3/25 20:00	10/1/25	APGE	Apogee Therapeutics, Inc.		Health	BioPrd	Biological Products, (No Diag	Dambkowski Carl	MA	O	Chief Me	17	S.d	-3,724	44.50	-84		295	D
10/3/25 19:32	10/2/25	PEN	Penumbra Inc	DE	Health	MdEq	Surgical & Medical Instrument	Grewal Harpreet	CA	D		6	S	-382	226.37	-2		9	D
10/3/25 19:31	10/1/25	PEN	Penumbra Inc	DE	Health	MdEq	Surgical & Medical Instrument	Roberts Johanna	CA	O	EVP,Gen.	16	S.d	-2,400	242.41	-10		67	D
10/3/25 19:30	10/1/25	PEN	Penumbra Inc	DE	Health	MdEq	Surgical & Medical Instrument	Wilder Thomas	CA	D		4	S	-328	256.58	-1		6	D
10/3/25 19:00	9/2/25	ATEC	Alphatec Holdings, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Miles Patrick	CA	DO	CEO	8	S.m	-9,331	13.55	-689		6,370	D
10/3/25 18:15	10/1/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hamilton James C	CA	O	Chief Me	5	S.m	-2,374	25.60	-93		272	D
10/3/25 18:00	10/1/25	HALO	Halozyme Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Torley Helen	CA	DO	P,CEO	9	S.dm	-25,407	61.97	-410		734	D
10/3/25 17:53	10/2/25	SGHT	Sight Sciences, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Bauerlein Alison	CA	O	CFO	7	S	-397	3.88	-102		650	D
10/3/25 17:53	10/1/25	SGHT	Sight Sciences, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Badawi Paul	CA	DOT	P,CEO	7	S	-509	3.78	-135		6,011	D
10/3/25 17:53	10/3/25	SGHT	Sight Sciences, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Badawi David	CA	DO	CTO	8	S	-135	3.71	-36		1,865	D
10/3/25 17:52	10/3/25	SGHT	Sight Sciences, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Hayden Jeremy B.	CA	O	GC	8	S	-195	3.77	-52		275	D
10/3/25 17:50	10/1/25	WRBY	Warby Parker Inc.	DE	Health	OthMd	Ophthalmic Goods	Gilboa David Abraham	NY	DO	Co-CEO	13	S.dm	-41,547	23.41	-1,775		33	D
10/3/25 17:24	10/1/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Belanoff Joseph K	CA	DO	CEO	9	S.dm	-18,904	78.45	-241		3,019	I
10/3/25 17:17	10/1/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Lyon Joseph Douglas	CA	O	See Rema	15	S.dm	-23,989	91.77	-261		10	D
10/3/25 17:15	10/1/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Maduck Sean	CA	O	See Rema	12	S.dm	-23,957	79.86	-300		118	D
10/3/25 17:14	10/2/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Poulton Jeffrey V.	MA	O	EVP,CFO	7	S.d	-4,298	346.38	-12		54	D
10/3/25 17:14	10/2/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Greenstreet Yvonne	MA	DO	CEO	11	S.dm	-38,057	303.03	-126		99	D
10/3/25 17:14	10/2/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Tanguler Tolga	MA	O	EVP,Chie	7	S.d	-3,804	368.12	-10		29	D
10/3/25 17:13	10/1/25	NTLA	Intellia Therapeutics, Inc.	DE	Health	Diagn	In Vitro & In Vivo Diagnostic	Schultes Birgit C	MA	O	EVP,Chie	1	S	-1	17.39	0	0	105	D
10/3/25 17:13	10/2/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Fitzgerald Kevin Joseph	MA	O	CSO,EVP,	8	S.dm	-10,057	283.98	-35		26	D
10/3/25 17:13	10/1/25	NTLA	Intellia Therapeutics, Inc.	DE	Health	Diagn	In Vitro & In Vivo Diagnostic	Dube Michael P	MA	O	VP,Chief	4	S	-112	14.49	-8		57	D
10/3/25 17:12	10/2/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Garg Pushkal	MA	O	EVP Chie	10	S.dm	-24,828	298.04	-83		25	D
10/3/25 17:02	10/1/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Watanabe Todd	CA	DO	See Rema	11	S.dm	-2,538	14.87	-171		1,161	D
10/3/25 17:01	10/1/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Welgus Howard G.	CA	D		17	S.d	-2,137	12.62	-169		205	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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