Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	Title	#f	T	TVal	Price	Qty	oc	Own	H
8/14/26 21:35	8/10/26	NTRA	Natera, Inc.	DE	Health	Health	Medical Laboratories	Sheena Jonathan	TX	DH	CO-FOUND	8	S.m	-7,236	288.99	-25		288	D
8/14/26 20:57	8/14/26	OTLK	Outlook Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Jahr Robert Charles	NJ	DO	CEO	1	P.d	0	0.00	152		152	D
8/14/26 20:46	8/12/26	CUE	Cue Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lin Shao-Lee	MA	DO	CEO	2	M.dm	1,607	9.60	167	31	706	D
8/14/26 20:46	8/12/26	CUE	Cue Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lin Shao-Lee	MA	DO	CEO	2	S.dm	-1,607	9.60	-167		706	D
8/14/26 19:52	8/12/26	OTLK	Outlook Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Sukhtian Ghiath M.		DT		2	P.d	7,500	0.6778	11,065	82	24,617	I
8/14/26 19:39	8/14/26	OTLK	Outlook Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Kenyon Lawrence A	NJ	DO	CFO	1	P.d	0	0.00	101	999%	107	D
8/14/26 19:25	8/12/26	TECX	Tectonic Therapeutic, Inc.	NY	Health	BioPrd	Biological Products, (No Diag	McNamara Peter	MA	O	Chief Sc	4	M.d	11	24.86	0	1	55	D
8/14/26 19:25	8/12/26	TECX	Tectonic Therapeutic, Inc.	NY	Health	BioPrd	Biological Products, (No Diag	McNamara Peter	MA	O	Chief Sc	4	S.d	-11	24.86	0		55	D
8/14/26 19:14	8/12/26	IRON	Disc Medicine, Inc.		Health	Drug	Pharmaceutical Preparations	Yu Jonathan Yen-Wen	MA	O	COO	10	M.d	2,420	40.99	59		54	D
8/14/26 19:14	8/12/26	IRON	Disc Medicine, Inc.		Health	Drug	Pharmaceutical Preparations	Yu Jonathan Yen-Wen	MA	O	COO	10	S.d	-2,420	40.99	-59		54	D
8/14/26 19:04	8/13/26	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lee Jennifer Kayden	MA	O	EVP,Head	2	M.d	9,899	74.74	132		0	D
8/14/26 19:04	8/13/26	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lee Jennifer Kayden	MA	O	EVP,Head	2	S.d	-9,899	74.74	-132	-100	0	D
8/14/26 19:01	8/12/26	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mazabraud Yann	MA	O	EVP,Head	2	M.d	6,938	66.95	104		56	D
8/14/26 19:01	8/12/26	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mazabraud Yann	MA	O	EVP,Head	2	S.d	-6,938	66.95	-104		56	D
8/14/26 18:22	8/14/26	KRYS	Krystal Biotech, Inc.		Health	BioPrd	Biological Products, (No Diag	Rossi Dino A	PA	D		1	S	-8,228	329.12	-25		50	D
8/14/26 18:01	8/12/26	MANE	Veradermics, Inc	DE	Health	Drug	Pharmaceutical Preparations	Childs John W	CT	D		1	S	-10,712	107.12	-100		2,102	I
8/14/26 17:52	8/14/26	ORKA	Oruka Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Quinlan Paul T	CA	O	GC	3	M.d	6,295	60.11	105		31	D
8/14/26 17:52	8/14/26	ORKA	Oruka Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Quinlan Paul T	CA	O	GC	3	S.d	-6,295	60.11	-105		31	D
8/14/26 17:48	8/13/26	LFST	Lifestance Health Group, Inc.	DE	Health	Health	Health Services	Deluca Teresa	AZ	D		1	S	-250	12.23	-20		105	D
8/14/26 17:44	8/12/26	SEPN	Septerna, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Third Rock Ventures V, L.P.	MA	T		2	S	-8,144	49.13	-166		17,530	D
8/14/26 17:42	8/13/26	ORKA	Oruka Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Agarwal Arjun	CA	O	SVP,Fina	9	M.dm	4,026	50.94	79		17	D
8/14/26 17:42	8/13/26	ORKA	Oruka Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Agarwal Arjun	CA	O	SVP,Fina	9	S.dm	-4,026	50.94	-79		17	D
8/14/26 17:24	8/14/26	CTTH	Ctt Pharmaceutical Holdings, Inc.	FL	Health	Drug	Pharmaceutical Preparations	Ctt Pharmaceutical Holdings, Inc.	FL	O	CEO	2	P	1	0.0645	10	0	9,355	D
8/14/26 17:15	8/12/26	PACS	Pacs Group, Inc.	DE	Health	Health	Skilled Nursing Care Faciliti	Jergensen Joshua	UT	O	P,COO	2	S	-3,624	45.31	-80		2,576	D
8/14/26 17:12	8/12/26	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Khattar Jack A.	MD	DO	P,CEO	1	M.d	0	0.00	30	1	2,216	D
8/14/26 17:11	8/12/26	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rubin Jonathan	MD	O	SVP,Chie	1	M.d	0	0.00	1	6	14	D
8/14/26 17:11	8/12/26	HOWL	Werewolf Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ra Capital Management, L.P.	MA	T		18	S.dm	-514,213	19.28	-26,675		61,064	I
8/14/26 17:11	8/12/26	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bhatt Padmanabh P.	MD	O	SVP of I	1	M.d	0	0.00	3	15	19	D
8/14/26 17:10	8/12/26	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mottola Frank	MD	O	SVP,Chie	1	M.d	0	0.00	2	9	20	D
8/14/26 17:09	8/12/26	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dec Timothy C	MD	O	Senior V	1	M.d	0	0.00	1	16	9	D
8/14/26 17:05	8/12/26	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Espinoza Octavio	FL	O	CFO	3	M.d	11,142	171.36	65		28	D
8/14/26 17:05	8/12/26	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Espinoza Octavio	FL	O	CFO	3	S.d	-11,142	171.36	-65		28	D
8/14/26 17:04	8/12/26	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Haas Jason	FL	D		4	M.d	4,264	179.64	24		5	D
8/14/26 17:04	8/12/26	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Haas Jason	FL	D		4	S.d	-4,264	179.64	-24		5	D
8/14/26 17:00	8/13/26	CGEM	Cullinan Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Michaelson Jennifer	MA	O	Chief Sc	4	M.d	897	12.45	72	79	163	D
8/14/26 17:00	8/13/26	CGEM	Cullinan Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Michaelson Jennifer	MA	O	Chief Sc	4	S.d	-897	12.45	-72		163	D
8/14/26 17:00	8/14/26	ACTU	Actuate Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Schmitt Daniel M	TX	DO	P,CEO,Di	1	M.d	0	0.00	272	41	932	D
8/14/26 16:54	8/13/26	MAZE	Maze Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Bernstein Harold	CA	O	P,R,D,CM	8	M.d	2,288	18.88	121		0	D
8/14/26 16:54	8/13/26	MAZE	Maze Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Bernstein Harold	CA	O	P,R,D,CM	8	S.d	-2,288	18.88	-121	-100	0	D
8/14/26 16:54	8/12/26	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Donovan Joanne M.	CO	O	CMO	2	M.dm	413	18.55	22		9	D
8/14/26 16:54	8/12/26	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Donovan Joanne M.	CO	O	CMO	2	S.dm	-413	18.55	-22		9	D
8/14/26 16:53	8/12/26	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Russell Alan J	CO	DO	Chief Sc	4	M.d	8,211	19.61	419		31	D
8/14/26 16:53	8/12/26	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Russell Alan J	CO	DO	Chief Sc	4	S.d	-8,211	19.61	-419		31	D
8/14/26 16:53	8/12/26	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Moore John R	CO	O	GC	2	M.d	220	12.55	18	999%	18	D
8/14/26 16:53	8/12/26	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Moore John R	CO	O	GC	2	S.d	-220	12.55	-18		18	D
8/14/26 16:53	8/12/26	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Derakhshan Behrad	CO	O	Chief Bu	2	M.d	223	12.16	18	137	32	D
8/14/26 16:53	8/12/26	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Derakhshan Behrad	CO	O	Chief Bu	2	S.d	-223	12.16	-18		32	D
8/14/26 16:52	8/12/26	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Koch Kevin	CO	DO	P,CEO	2	M.d	785	13.58	58		52	D
8/14/26 16:52	8/12/26	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Koch Kevin	CO	DO	P,CEO	2	S.d	-785	13.58	-58		52	D
8/14/26 16:41	8/13/26	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	126	M.d	402,354	341.12	1,180		749	I
8/14/26 16:41	8/13/26	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	126	S.d	-402,354	341.12	-1,180		749	I
8/14/26 16:36	8/13/26	BDX	Becton Dickinson & Co	NJ	Health	MdEq	Surgical & Medical Instrument	Polen Thomas E Jr	NJ	DO	CB,CEO,P	4	M.d	10,960	155.68	70	177	110	D
8/14/26 16:36	8/13/26	BDX	Becton Dickinson & Co	NJ	Health	MdEq	Surgical & Medical Instrument	Polen Thomas E Jr	NJ	DO	CB,CEO,P	4	S.d	-10,960	155.68	-70		110	D
8/14/26 16:35	8/13/26	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	Duato Joaquin	NJ	DO	CEO,CB	3	M.d	58,976	199.88	295	999%	308	D
8/14/26 16:35	8/13/26	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	Duato Joaquin	NJ	DO	CEO,CB	3	S.d	-58,976	199.88	-295		308	D
8/14/26 16:30	8/13/26	DNTH	Dianthus Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	Veness Adam M	NY	O	SVP,GC,S	5	M.dm	5,799	50.43	115		15	D
8/14/26 16:29	8/13/26	AMRX	Amneal Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Kiely John	NJ	D		1	S	-882	17.64	-50		200	D
8/14/26 16:18	8/10/26	MEDP	Medpace Holdings, Inc.	DE	Health	Biolab	Commercial Physical & Biologi	Troendle August J.	OH	DOT	P,CEO	3	S.m	-25,443	602.82	-42		5,372	D
8/14/26 16:12	8/12/26	TWST	Twist Bioscience Corp	DE	Health	BioPrd	Biological Products, (No Diag	Blake Katryn	CA	D		1	S	-275	122.88	-2		17	D
8/14/26 16:05	8/12/26	VCEL	Vericel Corp	MI	Health	BioPrd	Biological Products, (No Diag	McLaughlin Kevin F	MA	D		2	M.d	403	28.79	14	326	18	D
8/14/26 16:05	8/12/26	VCEL	Vericel Corp	MI	Health	BioPrd	Biological Products, (No Diag	McLaughlin Kevin F	MA	D		2	S.d	-403	28.79	-14		18	D
8/14/26 16:05	8/12/26	SLGL	Sol-Gel Technologies Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T		18	P.m	11,376	14.66	776	14	6,391	I
8/14/26 16:05	6/18/26	WGS	Genedx Holdings Corp.	DE	Health	Health	Health Services	Leproust Emily M.	CT	D		14	M.dm	28,045	64.25	436	100	872	D
8/14/26 16:01	8/6/26	AHCO	Adapthealth Corp.	DE	Health	Health	Home Health Care Services	Wolf Dale B	PA	D		2	P.m	371	6.18	60	51	177	D
8/14/26 16:01	8/12/26	INCY	Incyte Corp	DE	Health	Biolab	Commercial Physical & Biologi	Cagnoni Pablo J	DE	O	P,Global	3	S	-4,504	120.65	-37		215	D
8/14/26 14:37	8/13/26	CBLL	Ceribell, Inc.	DE	Health	ElcMd	Electromedical & Electrothera	Taylor Joseph Michael	CA	D		2	S	-408	21.92	-19		62	D
8/14/26 12:29	8/12/26	NIVF	Newgenivf Group Ltd	D8	Health	Health	Misc Health & Allied Services	Hrt Financial LP	NY	T		50	P.m	5,110	0.0907	56,362		7,750	D
8/14/26 12:29	8/13/26	NIVF	Newgenivf Group Ltd	D8	Health	Health	Misc Health & Allied Services	Hrt Financial LP	NY	T		50	S.m	-5,110	0.0907	-56,362		7,750	D
8/14/26 12:04	8/14/26	ABCL	Abcellera Biologics Inc.	A1	Health	Drug	Pharmaceutical Preparations	Booth Andrew		O	CFO	2	P.d	431	1.50	287	88	614	D
8/14/26 11:50	8/12/26	ABCL	Abcellera Biologics Inc.	A1	Health	Drug	Pharmaceutical Preparations	Hayden Michael R		D		2	P.m	1,540	23.19	66	5	1,516	I
8/14/26 06:10	8/12/26	BLTE	Belite Bio, Inc	E9	Health	Drug	Pharmaceutical Preparations	Chuang Hao-Yuan	CA	DO	CFO	1	S	-66	180.35	0	0	93	D
8/14/26 06:10	8/12/26	BLTE	Belite Bio, Inc	E9	Health	Drug	Pharmaceutical Preparations	Lin Yu-Hsin	CA	DO	CEO	1	S	-66	180.35	0	0	171	D
8/13/26 21:52	8/5/26	ATTO	Attovia Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Walsh Colin	NY	D		2	P.dm	12,537	18.15	691	30	3,021	I
8/13/26 21:52	8/5/26	ATTO	Attovia Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Walsh Colin	NY	D		2	S.dm	-12,537	18.15	-691		3,021	I
8/13/26 21:00	8/11/26	WVE	Wave Life Sciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Wagner Heidi L	MA	D		2	M.d	84	5.99	14	45	45	D
8/13/26 21:00	8/11/26	WVE	Wave Life Sciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Wagner Heidi L	MA	D		2	S.d	-84	5.99	-14		45	D
8/13/26 21:00	8/12/26	WVE	Wave Life Sciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rawcliffe Adrian	MA	D		1	S	-67	5.29	-13	-100	0	D
8/13/26 21:00	8/11/26	WVE	Wave Life Sciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Takanashi Ken		D		1	S	-23	6.01	-4	0	9,626	D
8/13/26 21:00	8/11/26	WVE	Wave Life Sciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tan Aik Na	MA	D		1	S	-3	6.01	0		25	D
8/13/26 20:54	8/11/26	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Lee Chan Henry		O	SVP,GC	10	M.d	3,501	270.73	13	4	347	D
8/13/26 20:54	8/11/26	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Lee Chan Henry		O	SVP,GC	10	S.d	-3,501	270.73	-13		347	D
8/13/26 20:18	8/13/26	CVRX	Cvrx, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Binkowski Brent	MN	O	COO	2	P	80	2.90	28	95	57	D
8/13/26 20:06	8/11/26	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Burnett Patrick	CA	O	See Rema	3	M.dm	474	15.33	31	35	119	D
8/13/26 20:06	8/11/26	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Burnett Patrick	CA	O	See Rema	3	S.dm	-474	15.33	-31		119	D
8/13/26 19:57	8/11/26	GKOS	Glaukos Corp	DE	Health	MdEq	Surgical & Medical Instrument	Gilliam Joseph E	CA	O	P,COO	2	M.d	13,961	116.34	120		73	D
8/13/26 19:57	8/11/26	GKOS	Glaukos Corp	DE	Health	MdEq	Surgical & Medical Instrument	Gilliam Joseph E	CA	O	P,COO	2	S.d	-13,961	116.34	-120		73	D
8/13/26 19:21	8/12/26	GH	Guardant Health, Inc.	DE	Health	Health	Medical Laboratories	Monroe Terilyn J.	CA	O	Chief Pe	3	M.d	8,696	90.01	97		23	D
8/13/26 19:21	8/12/26	GH	Guardant Health, Inc.	DE	Health	Health	Medical Laboratories	Monroe Terilyn J.	CA	O	Chief Pe	3	S.d	-8,696	90.01	-97		23	D
8/13/26 19:05	8/11/26	AMGN	Amgen Inc	DE	Health	BioPrd	Biological Products, (No Diag	Khosla Rachna	CA	O	SVP,Busi	2	S.dm	-1,550	344.16	-5		6	D
8/13/26 19:05	8/13/26	AMGN	Amgen Inc	DE	Health	BioPrd	Biological Products, (No Diag	Khosla Rachna	CA	O	SVP,Busi	2	M.dm	1,550	344.16	5	237	6	D
8/13/26 19:00	8/11/26	SEPN	Septerna, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bhatt Elizabeth	CA	O	P,COO	4	M.d	1,408	24.27	58	50	174	D
8/13/26 19:00	8/11/26	SEPN	Septerna, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bhatt Elizabeth	CA	O	P,COO	4	S.d	-1,408	24.27	-58		174	D
8/13/26 18:56	8/13/26	ICUI	Icu Medical Inc/De	DE	Health	MdEq	Surgical & Medical Instrument	Woolson Daniel	CA	O	P	2	S	-1,263	167.50	-8		22	D
8/13/26 17:43	8/13/26	BCDA	Biocardia, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Altman Peter	CA	DO	P,CEO	10	P.m	35	0.8984	39	12	376	D
8/13/26 17:33	8/10/26	SRTA	Strata Critical Medical, Inc.	DE	Health	Health	Health Services	Love Reginald	NY	D		1	S	-29	5.75	-5		146	D
8/13/26 17:22	6/5/26	BDSX	Biodesix Inc	DE	Health	Health	Medical Laboratories	Schuler Jack W	IL	TH	Emeritus	3	P.dm	1,133	4.28	265	4	6,408	I
8/13/26 17:14	8/11/26	ABT	Abbott Laboratories	IL	Health	Drug	Pharmaceutical Preparations	Morrone Louis H.	IL	O	EVP	1	S	-643	109.83	-6		71	M
8/13/26 17:04	8/11/26	KRRO	Korro Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Formela Jean Francois	MA	D		4	S.m	-4,071	14.21	-286		195	I
8/13/26 17:02	8/13/26	MRK	Merck & Co., Inc.	NJ	Health	Drug	Pharmaceutical Preparations	Guindo Chirfi	NJ	O	EVP,Acce	2	S	-3,315	132.60	-25		47	D
8/13/26 17:02	8/11/26	LFST	Lifestance Health Group, Inc.	DE	Health	Health	Health Services	Burdick Kenneth A	AZ	D		1	S	-5,755	11.51	-500		3,017	D
8/13/26 17:01	8/11/26	DNLI	Denali Therapeutics Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Schuth Alexander O.	CA	O	COFO,Sec	1	S	-72	25.07	-3	0	806	D
8/13/26 16:37	8/11/26	CRL	Charles River Laboratories International, Inc.		Health	Biolab	Commercial Physical & Biologi	Girshick Birgit	MA	DO	CEO	2	M.d	2,987	229.78	13	19	80	D
8/13/26 16:37	8/11/26	CRL	Charles River Laboratories International, Inc.		Health	Biolab	Commercial Physical & Biologi	Girshick Birgit	MA	DO	CEO	2	S.d	-2,987	229.78	-13		80	D
8/13/26 16:34	8/11/26	CRL	Charles River Laboratories International, Inc.		Health	Biolab	Commercial Physical & Biologi	Parisotto Shannon M	MA	O	CEVP,Dis	3	M.d	3,033	243.15	12	41	43	D
8/13/26 16:34	8/11/26	CRL	Charles River Laboratories International, Inc.		Health	Biolab	Commercial Physical & Biologi	Parisotto Shannon M	MA	O	CEVP,Dis	3	S.d	-3,033	243.15	-12		43	D
8/13/26 16:33	8/11/26	XENE	Xenon Pharmaceuticals Inc.	A1	Health	Drug	Pharmaceutical Preparations	Gannon Steven		D		2	S.d	-641	50.66	-13		12	D
8/13/26 16:32	8/13/26	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Cook Meredith	NJ	O	SVP,GC,S	3	S	-120	79.78	-2		78	D
8/13/26 16:28	8/12/26	ELAN	Elanco Animal Health Inc		Health	Drug	Pharmaceutical Preparations	Harrington Michael J	IN	D		1	P	109	21.82	5	4	131	D
8/13/26 16:22	8/12/26	AMRX	Amneal Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Shah Nikita	NJ	O	EVP	1	S	-2,564	17.51	-146		253	D
8/13/26 16:21	8/11/26	AMRX	Amneal Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Daly Jason B.	NJ	O	EVP,GC	1	S.m	-3,771	17.41	-217		35	D
8/13/26 16:21	8/11/26	AMRX	Amneal Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Buchi J Kevin	NJ	D		1	M	2,896	17.18	169	999%	169	I
8/13/26 16:15	8/12/26	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Lis William	MA	D		2	S	-340	21.87	-16		50	D
8/13/26 16:15	8/11/26	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Stevens Christopher James	NJ	O	COO	1	S	-128	3.50	-37		506	D
8/13/26 16:15	8/11/26	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chaudhuri Sarbani	NJ	O	See Rema	1	S	-16	3.50	-5		263	D
8/13/26 16:15	8/11/26	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Chen Yajing	MA	O	CFO	3	S.d	-55	6.02	-9		36	D
8/13/26 16:13	8/12/26	XFOR	X4 Pharmaceuticals, Inc	DE	Health	BioPrd	Biological Products, (No Diag	Volpone John	MA	O	P	1	S	-109	4.44	-25		265	D
8/13/26 16:12	8/11/26	MEDP	Medpace Holdings, Inc.	DE	Health	Biolab	Commercial Physical & Biologi	McCarthy Cornelius P. III	OH	D		4	S.d	-1,481	254.37	-6		13	D
8/13/26 16:11	8/12/26	MRK	Merck & Co., Inc.	NJ	Health	Drug	Pharmaceutical Preparations	Zachary Jennifer	NJ	O	EVP,GC	2	M.d	16,748	123.84	135		46	D
8/13/26 16:11	8/12/26	MRK	Merck & Co., Inc.	NJ	Health	Drug	Pharmaceutical Preparations	Zachary Jennifer	NJ	O	EVP,GC	2	S.d	-16,748	123.84	-135		46	D
8/13/26 16:10	8/12/26	XFOR	X4 Pharmaceuticals, Inc	DE	Health	BioPrd	Biological Products, (No Diag	Craig Adam R	MA	DO	Exec CB	1	S	-211	4.44	-47		329	D
8/13/26 16:05	8/13/26	ALT	Altimmune, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Durso Jerome Benedict	MD	DO	P,CEO	1	P	44	2.95	15	32	63	D
8/13/26 16:04	8/11/26	LIVN	Livanova Plc	X0	Health	ElcMd	Electromedical & Electrothera	Tezel Ahmet		O	Chief In	3	M.d	877	47.82	18		6	D
8/13/26 16:04	8/11/26	LIVN	Livanova Plc	X0	Health	ElcMd	Electromedical & Electrothera	Tezel Ahmet		O	Chief In	3	S.d	-877	47.82	-18		6	D
8/13/26 16:04	8/12/26	DXCM	Dexcom Inc	DE	Health	MdEq	Surgical & Medical Instrument	Heller Bridgette P	CA	D		1	S	-89	88.29	-1		30	D
8/13/26 10:50	8/12/26	EMBC	Embecta Corp.	DE	Health	MdEq	Surgical & Medical Instrument	Kurdikar Devdatt	NJ	DO	P,CEO	1	P	141	4.70	30	4	805	D
8/13/26 10:48	8/12/26	EMBC	Embecta Corp.	DE	Health	MdEq	Surgical & Medical Instrument	Elguicze Jacob	NJ	O	SVP,CFO	1	P	93	4.67	20	7	309	D
8/13/26 10:47	8/12/26	EMBC	Embecta Corp.	DE	Health	MdEq	Surgical & Medical Instrument	Mann Jeffrey Z	NJ	O	P,Pharm	1	P	100	4.99	20	8	263	D
8/13/26 10:45	6/22/26	SPTX	Seaport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hombach Robert J.	MA	D		2	P	460	7.92	58	90	123	I
8/13/26 09:54	8/6/26	PASG	Passage Bio, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Lynx1 Capital Management LP	PR	T		2	P.m	285	5.02	57	3	2,219	I
8/12/26 21:54	8/10/26	TAK	Takeda Pharmaceutical Co Ltd		Health	Drug	Pharmaceutical Preparations	Farajallah Awny Samaan Botros	MA	O	Chief Me	1	S	-240	17.10	-14		116	D
8/12/26 21:53	8/10/26	TAK	Takeda Pharmaceutical Co Ltd		Health	Drug	Pharmaceutical Preparations	Ibrahim Ramy Riad Ahmed	MA	O	P,PDT BU	1	S	-124	17.10	-7		103	D
8/12/26 21:53	8/10/26	TAK	Takeda Pharmaceutical Co Ltd		Health	Drug	Pharmaceutical Preparations	Pacheco Rhonda Janice	MA	O	P,U.S. B	1	S	-289	17.10	-17		183	D
8/12/26 21:51	8/10/26	TAK	Takeda Pharmaceutical Co Ltd		Health	Drug	Pharmaceutical Preparations	Duprey Lauren Rusckowski	MA	O	Chief Tr	1	S	-814	17.10	-48		226	D
8/12/26 21:50	8/10/26	TAK	Takeda Pharmaceutical Co Ltd		Health	Drug	Pharmaceutical Preparations	Plump Andrew Stewart	MA	DO	P,R,D	1	S	-2,828	17.10	-165		1,048	D
8/12/26 21:46	8/10/26	TAK	Takeda Pharmaceutical Co Ltd		Health	Drug	Pharmaceutical Preparations	Pignagnoli Agosti Marcello	MA	O	Head,Str	1	S	-393	17.10	-23		177	D
8/12/26 21:45	8/10/26	TAK	Takeda Pharmaceutical Co Ltd		Health	Drug	Pharmaceutical Preparations	Bitetti Teresa Marie	MA	O	P,OBU	1	S	-855	17.10	-50		252	D
8/12/26 21:43	8/3/26	HEPA	Hepion Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Stetz Gary S. II	NJ	D		1	P.d	25	0.0500	500		500	D
8/12/26 21:42	8/10/26	TAK	Takeda Pharmaceutical Co Ltd		Health	Drug	Pharmaceutical Preparations	Shannon Elaine Mary	MA	O	P,Global	2	S	-425	17.48	-24		67	D
8/12/26 21:41	8/3/26	CNTN	Canton Strategic Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Stetz Gary S.	NJ	D		2	P.dm	444	0.2113	2,100	164	3,384	D
8/12/26 21:39	8/10/26	TAK	Takeda Pharmaceutical Co Ltd		Health	Drug	Pharmaceutical Preparations	Ricci Gabriele	MA	O	Chief Da	1	S	-429	17.10	-25		172	D
8/12/26 21:39	8/3/26	HEPA	Hepion Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Purcell Michael J.	NJ	D		1	P.d	100	0.0500	2,000	160	3,250	D
8/12/26 21:36	8/3/26	HEPA	Hepion Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Appajosyula Sireesh	NJ	DO	COO	1	P.d	100	0.0500	2,000	160	3,250	D
8/12/26 21:34	8/3/26	HEPA	Hepion Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lopriore Vincent S	NJ	DO	Exec CB	1	P.d	500	0.0500	10,000	49	30,500	I
8/12/26 21:28	8/10/26	TAK	Takeda Pharmaceutical Co Ltd		Health	Drug	Pharmaceutical Preparations	Greenway Nicola Deidre Petal	MA	O	CHRO	2	S	-722	17.44	-41		60	D
8/12/26 21:27	8/10/26	TAK	Takeda Pharmaceutical Co Ltd		Health	Drug	Pharmaceutical Preparations	Kim Julie So-Young	MA	DO	P,CEO	1	S	-1,523	17.10	-89		391	D
8/12/26 21:25	8/10/26	TAK	Takeda Pharmaceutical Co Ltd		Health	Drug	Pharmaceutical Preparations	Platford Giles Richard	MA	O	P,IBU	1	S	-532	17.10	-31		316	D
8/12/26 21:23	8/10/26	TAK	Takeda Pharmaceutical Co Ltd		Health	Drug	Pharmaceutical Preparations	Furney Natalie Anne Marie	MA	O	Global G	1	S	-528	17.10	-31		204	D
8/12/26 19:41	8/11/26	SGMT	Sagimet Biosciences Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kemble George	CA	D		3	M.d	470	7.93	59	999%	62	D
8/12/26 19:41	8/11/26	SGMT	Sagimet Biosciences Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kemble George	CA	D		3	S.d	-470	7.93	-59		62	D
8/12/26 19:34	8/10/26	EXEL	Exelixis, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Beckerle Mary C	CA	D		1	S	-527	53.66	-10		16	D
8/12/26 19:33	8/10/26	ADPT	Adaptive Biotechnologies Corp	WA	Health	BioPrd	Biological Products, (No Diag	Bobulsky Susan	WA	O	Chief Co	7	S	-627	20.38	-31		417	D
8/12/26 19:33	8/10/26	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rodman David Malcom	PA	O	Chief Me	14	M.dm	1,588	18.81	84		63	D
8/12/26 19:33	8/10/26	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rodman David Malcom	PA	O	Chief Me	14	S.dm	-1,588	18.81	-84		63	D
8/12/26 19:06	8/10/26	BLCO	Bausch & Lomb Corp		Health	OthMd	Ophthalmic Goods	Munsch Frederick		O	SVP,Cont	1	S	-888	16.78	-53		46	D
8/12/26 18:55	7/13/26	BLLN	Billiontoone, Inc.	DE	Health	Health	Medical Laboratories	Ten Bosch John Roderick	CA	O	SVP of L	4	S	-1,122	113.17	-10		35	D
8/12/26 18:51	8/11/26	PTIX	Protagenic Therapeutics, Inc.New	DE	Health	Drug	Pharmaceutical Preparations	Armen Garo H	MA	DO	EXEC. CH	4	P	7	0.2036	34	999%	34	D
8/12/26 18:51	7/13/26	BLLN	Billiontoone, Inc.	DE	Health	Health	Medical Laboratories	Tsao David	CA	DO	CTO	6	M.d	5,612	56.12	100		1	D
8/12/26 18:51	7/13/26	BLLN	Billiontoone, Inc.	DE	Health	Health	Medical Laboratories	Tsao David	CA	DO	CTO	6	S.d	-5,612	56.12	-100		1	D
8/12/26 18:43	8/10/26	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	Patel Dinesh V Ph D	CA	DO	P,CEO	2	M.dm	17,049	85.24	200	62	523	D
8/12/26 18:43	8/10/26	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	Patel Dinesh V Ph D	CA	DO	P,CEO	2	S.dm	-17,049	85.24	-200		523	D
8/12/26 18:42	7/7/26	VERA	Vera Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fordyce Marshall	CA	DO	P,CEO	8	M.d	6,237	26.97	231	122	420	D
8/12/26 18:42	7/7/26	VERA	Vera Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fordyce Marshall	CA	DO	P,CEO	8	S.d	-6,237	26.97	-231		420	D
8/12/26 18:14	8/11/26	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Prins Richard K	CA	D		1	S	-162	20.30	-8		30	D
8/12/26 17:53	8/10/26	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Oyler John		DO	CEO	15	S.dm	-359,635	240.73	-1,494		51,730	D
8/12/26 17:51	8/12/26	AORT	Artivion, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Holloway Jean F	GA	O	SVP,GC	1	S	-28	28.49	-1		184	D
8/12/26 17:47	8/10/26	IMNM	Immunome Inc.	DE	Health	Drug	Pharmaceutical Preparations	Barchas Isaac	WA	D		4	S.m	-9,945	23.64	-421		620	M
8/12/26 17:30	8/10/26	IOVA	Iovance Biotherapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Kirby Daniel Gordon	CA	O	Chief Co	1	M.d	0	0.00	10	7	155	D
8/12/26 17:27	8/11/26	BDX	Becton Dickinson & Co	NJ	Health	MdEq	Surgical & Medical Instrument	Goette Roland	NJ	O	EVP,P,EM	1	S	-441	180.84	-2		17	D
8/12/26 17:14	8/11/26	CERS	Cerus Corp	DE	Health	MdEq	Surgical & Medical Instrument	Bjerkholt Eric	CA	D		5	S.d	-1,796	46.24	-39		309	D
8/12/26 17:07	6/29/26	REPL	Replimune Group, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Patel Sushil	MA	DO	CEO	4	M.d	1,860	21.83	85	12	769	D
8/12/26 17:07	6/29/26	REPL	Replimune Group, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Patel Sushil	MA	DO	CEO	4	S.d	-1,860	21.83	-85		769	D
8/12/26 17:07	8/10/26	LFST	Lifestance Health Group, Inc.	DE	Health	Health	Health Services	Paunovich Vukasin	AZ	O	CTO	1	S	-482	10.85	-44		247	D
8/12/26 17:07	8/10/26	HTFL	Heartflow, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Farquhar John C.M.	CA	DO	CEO	5	S.d	-3,427	24.87	-138		497	D
8/12/26 17:06	8/10/26	REPL	Replimune Group, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Hill Emily Luisa	MA	O	CFO	2	S	-188	9.77	-19		237	D
8/12/26 17:05	8/10/26	REPL	Replimune Group, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Xynos Konstantinos	MA	O	Chief Me	2	S	-220	8.63	-25		236	D
8/12/26 17:04	8/10/26	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Adsett Roger	NJ	O	COO	3	M.d	37,113	76.99	482		99	D
8/12/26 17:04	8/10/26	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Adsett Roger	NJ	O	COO	3	S.d	-37,113	76.99	-482		99	D
8/12/26 17:04	8/10/26	REPL	Replimune Group, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Schwendenman Andrew	MA	O	Chief Ac	2	S	-139	8.96	-16		107	D
8/12/26 17:03	8/11/26	BFLY	Butterfly Network, Inc.	DE	Health	OthMd	X-Ray Apparatus & Tubes & Rel	Caezza Nicholas	MA	O	Deputy G	2	S	-105	8.98	-12		310	D
8/12/26 17:02	8/10/26	ICLR	Icon Plc		Health	Biolab	Commercial Physical & Biologi	Whitaker Anne Clem		D		2	M.d	138	53.70	3		1	D
8/12/26 17:02	8/11/26	ICLR	Icon Plc		Health	Biolab	Commercial Physical & Biologi	Whitaker Anne Clem		D		2	S.d	-138	53.70	-3		1	D
8/12/26 17:02	8/10/26	LFST	Lifestance Health Group, Inc.	DE	Health	Health	Health Services	Tpg Gp A, LLC	TX	T		2	S	-148,963	10.76	-13,846		101,866	I
8/12/26 17:01	8/10/26	ICLR	Icon Plc		Health	Biolab	Commercial Physical & Biologi	O'Neill Julie		D		2	M.d	150	56.79	3	305	4	D
8/12/26 17:01	8/11/26	ICLR	Icon Plc		Health	Biolab	Commercial Physical & Biologi	O'Neill Julie		D		2	S.d	-150	56.79	-3		4	D
8/12/26 17:00	8/10/26	ICLR	Icon Plc		Health	Biolab	Commercial Physical & Biologi	Murray Ciaran		D		2	M.d	440	82.14	5	35	20	D
8/12/26 17:00	8/11/26	ICLR	Icon Plc		Health	Biolab	Commercial Physical & Biologi	Murray Ciaran		D		2	S.d	-440	82.14	-5		20	D
8/12/26 17:00	8/10/26	ICLR	Icon Plc		Health	Biolab	Commercial Physical & Biologi	Murphy Ronan Martin		D		2	M.d	138	53.70	3	202	4	D
8/12/26 17:00	8/11/26	ICLR	Icon Plc		Health	Biolab	Commercial Physical & Biologi	Murphy Ronan Martin		D		2	S.d	-138	53.70	-3		4	D
8/12/26 16:59	8/10/26	ICLR	Icon Plc		Health	Biolab	Commercial Physical & Biologi	McCague Eugene Pacelli		D		2	M.d	138	53.70	3	208	4	D
8/12/26 16:59	8/11/26	ICLR	Icon Plc		Health	Biolab	Commercial Physical & Biologi	McCague Eugene Pacelli		D		2	S.d	-138	53.70	-3		4	D
8/12/26 16:59	8/10/26	LFST	Lifestance Health Group, Inc.	DE	Health	Health	Health Services	Miller Lisa K	AZ	O	COO	1	S	-520	10.85	-48		281	D
8/12/26 16:50	8/12/26	OMDA	Omada Health, Inc.	DE	Health	Health	Health Services	Shao Wei-Li	CA	O	P	3	S	-371	21.18	-17		317	D
8/12/26 16:48	8/10/26	OMDA	Omada Health, Inc.	DE	Health	Health	Health Services	Cook Steven L.	CA	O	CFO	20	M.dm	5,785	15.91	364		187	D
8/12/26 16:48	8/10/26	OMDA	Omada Health, Inc.	DE	Health	Health	Health Services	Cook Steven L.	CA	O	CFO	20	S.dm	-5,785	15.91	-364		187	D
8/12/26 16:47	8/10/26	ICLR	Icon Plc		Health	Biolab	Commercial Physical & Biologi	Grais Linda		D		2	M.d	138	53.70	3	72	6	D
8/12/26 16:47	8/11/26	ICLR	Icon Plc		Health	Biolab	Commercial Physical & Biologi	Grais Linda		D		2	S.d	-138	53.70	-3		6	D
8/12/26 16:47	8/10/26	ICLR	Icon Plc		Health	Biolab	Commercial Physical & Biologi	Climax John Dr		D		2	M.d	138	53.70	3		2	D
8/12/26 16:47	8/11/26	ICLR	Icon Plc		Health	Biolab	Commercial Physical & Biologi	Climax John Dr		D		2	S.d	-138	53.70	-3		2	D
8/12/26 16:46	8/10/26	OMDA	Omada Health, Inc.	DE	Health	Health	Health Services	Gracey Craig	CA	O	Chief Ac	18	M.dm	756	14.74	51		15	D
8/12/26 16:46	8/10/26	OMDA	Omada Health, Inc.	DE	Health	Health	Health Services	Gracey Craig	CA	O	Chief Ac	18	S.dm	-756	14.74	-51		15	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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