Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	Title	#f	T	TVal	Price	Qty	oc	Own	H
10/17/25 21:05	10/15/25	NTRA	Natera, Inc.	DE	Health	Health	Medical Laboratories	Sheena Jonathan	TX	DH	CO-FOUND	5	S.dm	-4,359	172.43	-25		317	M
10/17/25 21:00	10/15/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Venker Eric	X0	O	P,Immuno	6	S.dm	-55,145	15.52	-3,553		1,654	D
10/17/25 20:44	10/17/25	ARTV	Artiva Biotherapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Aslan Fred	CA	DO	P,CEO	2	S	-223	4.36	-51		382	D
10/17/25 19:55	10/15/25	BLFS	Biolife Solutions Inc	DE	Health	ElcMd	Electromedical & Electrothera	Casdin Partners Master Fund, L.P.	NY	T		3	S	-44,910	25.66	-1,750		7,207	I
10/17/25 19:29	10/17/25	LXEO	Lexeo Therapeutics, Inc.		Health	BioPrd	Biological Products, (No Diag	See Tai Sandi	NY	O	Chief De	2	S	-37	8.56	-4		66	D
10/17/25 19:28	10/17/25	LXEO	Lexeo Therapeutics, Inc.		Health	BioPrd	Biological Products, (No Diag	Robertson Jenny	NY	O	GC	2	S	-34	8.37	-4		69	D
10/17/25 19:28	10/17/25	LXEO	Lexeo Therapeutics, Inc.		Health	BioPrd	Biological Products, (No Diag	Otero Jose Manuel	NY	O	Chief Te	2	S	-32	6.49	-5		64	D
10/17/25 19:26	10/17/25	LXEO	Lexeo Therapeutics, Inc.		Health	BioPrd	Biological Products, (No Diag	Adler Eric	NY	O	Chief Me	2	S	-33	8.29	-4		73	D
10/17/25 19:26	10/17/25	LXEO	Lexeo Therapeutics, Inc.		Health	BioPrd	Biological Products, (No Diag	Townsend Richard Nolan	NY	DO	CEO	3	S	-135	7.97	-17		242	D
10/17/25 18:33	10/15/25	VOR	Vor Biopharma Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Reprogrammed Interchange LLC	CA	T		11	S.m	-26,547	4.01	-6,628		38,303	D
10/17/25 18:03	10/15/25	VOR	Vor Biopharma Inc.		Health	BioPrd	Biological Products, (No Diag	Ra Capital Management, L.P.	MA	DT		1	S.m	-13,707	29.54	-464		15	I
10/17/25 17:53	10/15/25	KROS	Keros Therapeutics, Inc.		Health	Drug	Pharmaceutical Preparations	Pontifax Management 4 G.P. (2015) Ltd.	L3	T		1	S	-84,975	17.75	-4,787	-100	11	I
10/17/25 17:11	8/26/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cloonan Michael	MA	DO	P,CEO	4	S.dm	-2,709	27.04	-100		547	D
10/17/25 16:41	10/15/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bitterman Kevin	MA	D		8	S.m	-19,663	72.70	-270		1,148	I
10/17/25 16:39	10/10/25	MLSS	Milestone Scientific Inc.	DE	Health	Orthop	Orthopedic, Prosthetic & Surg	Bp4 S.R.L.	L6	T		5	S.m	-67	0.5156	-129		9,299	D
10/17/25 16:32	8/15/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Porter James Richard	MA	DO	P,CEO	3	S.d	-6,618	81.71	-81		249	D
10/17/25 16:32	10/15/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Miller Deborah Ann	MA	O	GC	1	S.dm	-2,540	90.72	-28		49	D
10/17/25 16:31	8/7/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pelish Henry E.	MA	O	Chief Sc	4	S.dm	-2,879	85.94	-34		66	D
10/17/25 16:31	10/15/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Balcom Alexandra	MA	O	CFO	4	S.dm	-7,694	86.19	-89		62	D
10/17/25 16:28	10/16/25	SDGR	Schrodinger, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dugan Margaret	NY	O	Chief Me	1	S	-29	21.07	-1		25	D
10/17/25 16:27	10/15/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McCarthy Teresa	CA	O	CHRO	3	S.d	-2,090	46.44	-45		97	D
10/17/25 16:15	10/15/25	VIR	Vir Biotechnology, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Svf Endurance (Cayman) Ltd	E9	T		4	S.m	-7,870	5.86	-1,344		16,160	I
10/17/25 16:15	10/16/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Watson David O.	MA	O	GC	4	S	-910	26.01	-35		204	D
10/17/25 16:10	10/16/25	PRAX	Praxis Precision Medicines, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Adage Capital Management, L.P.	MA	T		1	S	-33,198	105.76	-314		4,422	I
10/17/25 16:01	10/15/25	INCY	Incyte Corp	DE	Health	Biolab	Commercial Physical & Biologi	Denton Sheila A.	DE	O	EVP,GC	6	S.dm	-519	84.67	-6		33	D
10/17/25 15:08	8/13/25	MRAI	Marpai, Inc.	DE	Health	Health	Misc Health & Allied Services	Intelligent Fanatics Capital Management LLC	PA	T		1	S.m	-271	1.44	-188		3,541	M
10/17/25 14:01	10/15/25	AQST	Aquestive Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jung Cassie	NJ	O	COO	2	S.d	-785	6.05	-130		285	D
10/17/25 14:01	10/15/25	AQST	Aquestive Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kraus Carl N	NJ	O	Chief Me	1	S	-142	7.00	-20		282	D
10/17/25 14:00	10/15/25	AQST	Aquestive Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Boyd Peter E.	NJ	O	See Rema	3	S	-213	6.07	-35		288	D
10/16/25 21:35	10/15/25	GILD	Gilead Sciences, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Dickinson Andrew D	CA	O	CFO	3	S	-875	116.73	-8		160	D
10/16/25 21:28	10/15/25	GILD	Gilead Sciences, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Mercier Johanna	CA	O	Chief Co	3	S.d	-4,014	118.06	-34		114	D
10/16/25 20:16	10/16/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Swayze Eric	CA	O	EVP Rese	4	S.dm	-2,823	62.54	-45		37	I
10/16/25 20:16	10/15/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Parshall B Lynne	CA	D		3	S	-1,587	52.89	-30		86	D
10/16/25 20:16	10/15/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Devers Shannon L.	CA	O	EVP,Chie	2	S.dm	-724	69.41	-10		17	D
10/16/25 20:15	10/14/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Birchler Brian	CA	O	EVP,Corp	1	S.dm	-1,724	72.13	-24		57	D
10/16/25 18:18	10/15/25	GRAL	Grail, Inc.		Health	Health	Medical Laboratories	Ragusa Robert P	CA	DO	CEO	1	S	-499	68.88	-7		727	D
10/16/25 18:17	8/19/25	GRAL	Grail, Inc.		Health	Health	Medical Laboratories	Ofman Joshua J.	CA	O	P	4	S.m	-7,017	63.64	-110		488	D
10/16/25 18:00	10/14/25	BGMS	Bio Green Med Solution, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ong Yee Lung	N8	T		1	S	-815	6.00	-136		269	D
10/16/25 17:44	10/16/25	AURA	Aura Biosciences, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Plavsic Mark	MA	O	CTO	1	S	-77	6.35	-12		197	D
10/16/25 17:05	9/2/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Blum Robert I	CA	DO	P,CEO	6	S	-1,442	48.08	-30		392	D
10/16/25 16:41	10/15/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cohlhepp Ryan	MA	DO	P,COO	2	S.dm	-1,139	18.08	-63		203	D
10/16/25 16:35	10/14/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Tessari Eben	X0	O	COO	7	S.dm	-11,865	34.97	-339		50	D
10/16/25 16:30	10/15/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	15	S.dm	-49,140	423.62	-116		644	D
10/16/25 16:30	10/15/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bredt David	MA	O	Chief Sc	3	S	-552	21.66	-26		427	D
10/16/25 16:30	9/4/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ceesay Abraham	MA	DO	CEO	3	S	-2,357	26.28	-90		722	D
10/16/25 16:21	10/7/25	EBS	Emergent Biosolutions Inc.	DE	Health	Drug	Pharmaceutical Preparations	Glessner Coleen	MD	O	EVP,Qual	1	S	-306	10.00	-31		144	D
10/16/25 16:15	10/14/25	CDRE	Cadre Holdings, Inc.	DE	Health	Orthop	Orthopedic, Prosthetic & Surg	Williams Brad	FL	O	P	2	S	-318	38.50	-8		114	D
10/16/25 16:15	10/16/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Seshadri Vishwas	OH	DO	CEO	2	S.m	-236	5.31	-45		1,190	D
10/16/25 16:13	8/15/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Hussain Iqbal J	X0	O	GC	4	S.dm	-1,209	20.85	-58		111	D
10/16/25 16:01	10/14/25	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Militello John	NJ	O	See Rema	3	S.m	-139	3.76	-37		67	D
10/15/25 20:56	10/13/25	LVTX	Lava Therapeutics Nv	P7	Health	Drug	Pharmaceutical Preparations	Cooperatieve Gilde Healthcare IV U.A.	P7	T		2	S.m	-917	1.52	-602		5,294	D
10/15/25 20:12	10/10/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dunlop A. Sinclair	MA	D		3	S	-2,153	23.08	-93		223	M
10/15/25 20:07	9/12/25	BYSI	Beyondspring Inc.		Health	Drug	Pharmaceutical Preparations	Decheng Capital China Life Sciences Usd Fund Iii, L.P.	CA	T		16	S.m	-1,792	2.48	-723		4,488	I
10/15/25 19:28	10/15/25	ACLX	Arcellx, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Gilson Michelle	CA	O	CFO	2	S.m	-1,000	88.41	-11		14	D
10/15/25 19:04	10/13/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Levy Adam Scott	PA	O	CFO,Secr	2	S.m	-1,529	18.11	-84		133	D
10/15/25 19:04	10/13/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Congleton Jon	PA	DO	CEO	1	S	-644	42.67	-15		831	D
10/15/25 19:04	10/15/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rodman David Malcom	PA	O	Chief Me	3	S.d	-1,002	30.28	-33		93	D
10/15/25 18:47	10/15/25	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	Hopkinson Craig C.	MA	O	EVP R,D,	1	S.d	-284	31.53	-9		74	D
10/15/25 18:33	10/10/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Booth Bruce	MA	D		3	S.m	-9,793	30.30	-323		3,615	I
10/15/25 18:31	10/10/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Swisher Daniel N Jr	CA	D		3	S.d	-511	77.43	-7	-100	0	D
10/15/25 18:00	10/13/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mazumdar Claire	MA	DO	CEO	1	S.dm	-467	18.88	-25		310	D
10/15/25 17:35	8/18/25	CRSP	Crispr Therapeutics AG	V8	Health	BioPrd	Biological Products, (No Diag	Kulkarni Samarth	MA	DO	CEO	2	S.d	-1,043	60.22	-17		293	D
10/15/25 17:35	10/14/25	CRSP	Crispr Therapeutics AG	V8	Health	BioPrd	Biological Products, (No Diag	Kasinger James R.	MA	O	GC,Secre	1	S.d	-72	66.60	-1		83	D
10/15/25 17:28	10/15/25	KYMR	Kymera Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Gollob Jared	MA	O	Chief Me	2	S.d	-3,846	61.35	-63		118	D
10/15/25 17:09	10/13/25	RVMD	Revolution Medicines, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Kelsey Stephen Michael	CA	O	See Rema	3	S.dm	-7,017	45.17	-155		289	D
10/15/25 16:36	10/13/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Schundler Russell	NC	O	GC	2	S.d	-214	24.08	-9		595	D
10/15/25 16:34	10/13/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Kaseta Michael	NC	O	CFO,COO	4	S.d	-1,429	22.77	-63		376	D
10/15/25 16:34	10/13/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Moomaw Scott	NC	O	Chief Co	2	S.d	-2,138	28.29	-76		155	D
10/15/25 16:33	10/13/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Saggar Rajeev	NC	O	Chief Me	3	S.d	-719	25.80	-28		269	D
10/15/25 16:32	10/13/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Boyle Dana	NC	O	Chief Ac	3	S	-58	22.47	-3		187	D
10/15/25 16:32	10/6/25	SPRB	Spruce Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Parkman Healthcare Partners LLC	CT	T		2	S	-10	19.14	-1		1	I
10/15/25 16:31	9/2/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Jeffs Roger	NC	DO	CEO	4	S.dm	-13,848	106.18	-130		2,752	D
10/15/25 16:31	10/13/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Adair Jason	NC	O	Chief Bu	3	S.dm	-834	27.22	-31		193	D
10/15/25 16:30	10/13/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Benkowitz Michael	MD	O	P,COO	7	S.dm	-63,788	421.39	-151		3	I
10/15/25 16:30	10/13/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Krepp Sarah	NC	O	Chief Hu	2	S	-46	24.03	-2		143	D
10/15/25 16:15	9/3/25	CGON	Cg Oncology, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Post Leonard E	CA	D		4	S.d	-307	38.35	-8	-100	0	D
10/15/25 13:24	10/15/25	KROS	Keros Therapeutics, Inc.		Health	Drug	Pharmaceutical Preparations	Adar1 Capital Management, LLC	TX	T		1	S	-95,659	17.75	-5,389	-100	0	I
10/14/25 20:11	10/10/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cheng Andrew	CA	DO	P,CEO	3	S.dm	-4,452	48.49	-92		526	D
10/14/25 19:49	10/13/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Cook Meredith	MN	O	SVP,GC,S	3	S	-111	92.46	-1		76	D
10/14/25 18:00	10/10/25	BGMS	Bio Green Med Solution, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fitters Diversified Berhad	N8	T		2	S	-1,022	5.28	-193		557	D
10/14/25 17:30	9/11/25	BLFS	Biolife Solutions Inc	DE	Health	ElcMd	Electromedical & Electrothera	Wichterman Troy	WA	O	CFO	3	S	-65	26.68	-2		185	D
10/14/25 17:30	9/11/25	BLFS	Biolife Solutions Inc	DE	Health	ElcMd	Electromedical & Electrothera	Berard Todd	WA	O	CMO	4	S	-282	25.62	-11		134	D
10/14/25 17:30	10/9/25	BLFS	Biolife Solutions Inc	DE	Health	ElcMd	Electromedical & Electrothera	Mathew Aby J.	WA	O	EVP,Chie	3	S	-44	26.55	-2	0	352	D
10/14/25 17:30	9/15/25	BLFS	Biolife Solutions Inc	DE	Health	ElcMd	Electromedical & Electrothera	Aebersold Sarah	WA	O	CHRO	4	S	-35	26.04	-1		78	D
10/14/25 17:30	9/11/25	BLFS	Biolife Solutions Inc	DE	Health	ElcMd	Electromedical & Electrothera	Foster Karen A.	WA	O	Chief Qu	3	S	-36	26.57	-1		194	D
10/14/25 16:33	10/10/25	CLPT	Clearpoint Neuro, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Burnett Joseph	CA	DO	CEO,P	1	S	-714	26.98	-26		228	I
10/14/25 16:31	10/9/25	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	Bunn Paul A.	MA	D		1	S	-75	9.06	-8		8	D
10/14/25 16:17	10/10/25	HIMS	Hims & Hers Health, Inc.	DE	Health	Health	Offices & Clinics of Doctors	Chi Michael	CA	O	Chief Co	7	S.dm	-3,784	59.50	-64		311	D
10/14/25 16:17	10/13/25	HIMS	Hims & Hers Health, Inc.	DE	Health	Health	Offices & Clinics of Doctors	Boughton Soleil	CA	O	GC	6	S	-830	53.11	-16		166	D
10/14/25 16:10	10/10/25	FENC	Fennec Pharmaceuticals Inc.	A1	Health	BioPrd	Biological Products, (No Diag	Rallis Chris A	NC	D		1	S.d	-16	9.24	-2		57	D
10/14/25 16:05	10/9/25	CVKD	Cadrenal Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Szot Matthew K	FL	O	CFO	5	S.m	-278	14.03	-20		31	D
10/14/25 16:05	10/9/25	CVKD	Cadrenal Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pham Quang X	FL	DOT	CEO,CB	5	S.m	-278	14.05	-20		413	D
10/14/25 16:05	10/13/25	IRMD	Iradimed Corp	DE	Health	MdEq	Surgical & Medical Instrument	Susi Roger E.	FL	DOT	CEO,P,CB	5	S	-1,785	71.41	-25		4,583	I
10/14/25 16:04	10/9/25	FDMT	4D Molecular Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Bizily Scott	CA	O	GC	2	S	-43	9.00	-5		8	D
10/14/25 16:01	10/10/25	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	Waddill William D.	CA	D		3	S.d	-1,473	73.67	-20		9	D
10/14/25 16:00	7/24/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	Lilly Endowment Inc	IN	T		13	S	-1,208,375	814.46	-1,484		95,737	D
10/14/25 13:16	8/18/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	Moreadith Randall	AL	O	Chief Sc	8	S.dm	-534	6.32	-85	-100	0	D
10/14/25 12:15	10/13/25	RARE	Ultragenyx Pharmaceutical Inc.	DE	Health	Drug	Pharmaceutical Preparations	Horn Howard	CA	O	CFO	1	S	-250	31.51	-8		98	D
10/14/25 07:55	10/13/25	KYMR	Kymera Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Albers Jeffrey W.	MA	D		1	S.d	-296	59.19	-5	-100	0	D
10/10/25 19:17	10/10/25	ZVRA	Zevra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McFarlane Neil F.	FL	DO	P,CEO	1	S.d	-211	10.82	-20		222	D
10/10/25 18:38	9/10/25	RGNX	Regenxbio Inc.		Health	BioPrd	Biological Products, (No Diag	Simpson Curran	MD	DO	CEO	3	S	-417	11.52	-36		245	D
10/10/25 18:17	9/12/25	BGMS	Bio Green Med Solution, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kua Khai Loon	N8	T		2	S.m	-400	6.04	-66		385	D
10/10/25 18:03	10/10/25	RXRX	Recursion Pharmaceuticals, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Gibson Christopher	UT	DO	CEO	5	S.d	-5,299	5.20	-1,018		995	D
10/10/25 17:40	9/4/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kumar Neil	CA	DO	CEO	4	S.m	-13,503	50.73	-266		5,857	I
10/10/25 17:33	10/9/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Khattar Jack A.	MD	DO	P,CEO	13	S.dm	-18,547	45.67	-406		2,212	D
10/10/25 17:27	10/9/25	EXAS	Exact Sciences Corp	DE	Health	Health	Medical Laboratories	Herriott James	WI	O	SVP,GC,S	1	S	-90	60.00	-2		16	D
10/10/25 17:25	10/9/25	EXAS	Exact Sciences Corp	DE	Health	Health	Medical Laboratories	Doyle James Edward	WI	D		2	S	-182	52.34	-3		60	D
10/10/25 17:23	10/9/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Raben David	MA	O	Chief Me	1	S.d	-406	18.45	-22		35	D
10/10/25 17:22	10/9/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hyep Ivan	MA	O	CFO	2	S.dm	-670	18.21	-37		145	D
10/10/25 16:56	10/8/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Lee Chan Henry	V8	O	SVP,GC	4	S.d	-10,586	324.61	-33		266	D
10/10/25 16:30	10/8/25	ALZN	Alzamend Neuro, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ault Milton C III	NV	D		10	S.dm	-2,212	2.44	-905		124	I
10/10/25 16:21	10/9/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Newhall Charles W III	MD	D		4	S	-1,539	49.65	-31		134	D
10/10/25 16:18	10/8/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Scadden David	MA	D		3	S.d	-24	40.33	-1		18	D
10/10/25 16:15	10/9/25	CGON	Cg Oncology, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Mulay James	CA	D		4	S.dm	-2,496	36.52	-68	-100	0	D
10/10/25 16:12	10/8/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kaye Edward M. Md	MA	D		7	S.dm	-4,394	27.18	-162		177	D
10/10/25 16:05	10/8/25	TWST	Twist Bioscience Corp	DE	Health	BioPrd	Biological Products, (No Diag	Laponis Adam	CA	O	CFO	3	S.m	-389	31.62	-12		103	D
10/10/25 16:03	10/8/25	IMVT	Immunovant, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Geffner Michael	NY	O	Chief Me	2	S	-64	17.51	-4		222	D
10/10/25 16:01	10/8/25	IMVT	Immunovant, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Stout Jay S	NY	O	CTO	2	S	-77	17.48	-4		205	D
10/10/25 16:01	10/8/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	Anderman Todd	MA	O	GC	1	S	-137	12.34	-11		88	D
10/9/25 18:58	9/8/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rolph Timothy	CA	O	Chief Sc	4	S.d	-1,768	46.47	-38		167	D
10/9/25 17:51	10/7/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Guyer William	CA	O	Chief De	4	S.d	-5,722	76.27	-75		5	D
10/9/25 17:31	10/7/25	FENC	Fennec Pharmaceuticals Inc.	A1	Health	BioPrd	Biological Products, (No Diag	Southpoint Capital Advisors LP	NY	T		1	S.m	-636	9.48	-67		4,010	I
10/9/25 17:21	10/7/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Patel Anish	CO	O	COO	3	S	-391	19.53	-20		290	I
10/9/25 16:41	10/7/25	INBX	Inhibrx Biosciences, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Viking Global Investors LP	CT	T		1	S	-11,288	32.25	-350		103	I
10/9/25 16:22	8/19/25	HOOK	Hookipa Pharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	Peters Malte	NY	DO	CEO	2	S	-48	0.8745	-54		80	D
10/9/25 13:37	10/8/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Degnan Chris	NJ	O	CFO	1	S.d	-37	16.85	-2		2	D
10/9/25 11:03	10/7/25	RMD	Resmed Inc	DE	Health	MdEq	Surgical & Medical Instrument	Farrell Michael J.	CA	O	CEO	3	S.d	-6,731	280.16	-24		470	D
10/8/25 21:08	10/6/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tabuteau Herriot	NY	DOT	CEO	2	S.dm	-12,780	118.04	-108		7,352	D
10/8/25 20:12	10/6/25	SGHT	Sight Sciences, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Taylor Brenton	CA	O	EVP,Oper	1	S	-2	3.37	-1	0	185	D
10/8/25 19:48	10/1/25	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hunter Heather	MI	O	SVP,COO	1	S	-3	1.19	-3		135	D
10/8/25 19:08	10/6/25	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jarrett Jennifer	CA	O	COO	1	S.dm	-750	14.92	-50		214	D
10/8/25 18:37	10/6/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	O'Neil Patrick R.	CA	O	EVP CLO,	6	S.dm	-13,812	63.94	-216		57	D
10/8/25 18:36	10/6/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Monia Brett P	CA	DO	CEO	3	S.d	-12,434	60.16	-207		180	D
10/8/25 18:36	10/6/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Baroldi Joseph	CA	O	EVP,Chie	5	S.d	-3,837	62.27	-62		35	D
10/8/25 17:37	10/6/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Piscitelli Dominic	CA	O	CFO	1	S.d	-160	14.52	-11		48	D
10/8/25 17:35	10/6/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chacko Jacob	CA	DO	P,CEO	3	S.m	-2,865	11.46	-250		656	D
10/8/25 16:35	9/9/25	SERA	Sera Prognostics, Inc.	DE	Health	Health	Medical Laboratories	Harrison Robert Gardner	UT	O	CIO	5	S	-43	2.59	-17		109	D
10/8/25 16:34	10/6/25	STE	Steris Plc	L2	Health	Orthop	Orthopedic, Prosthetic & Surg	Carestio Daniel A	L2	DO	P,CEO	1	S	-38	241.82	0	0	51	D
10/8/25 16:16	10/7/25	CARM	Carisma Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Klichinsky Michael	PA	O	Chief Sc	2	S.dm	-139	0.2565	-541	-100	0	D
10/8/25 16:10	8/5/25	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	Taiwan Carbon Nano Technology Corp	F5	T		4	S.m	-128	2.98	-43		1,049	D
10/8/25 16:05	10/6/25	TWST	Twist Bioscience Corp	DE	Health	BioPrd	Biological Products, (No Diag	Leproust Emily M.	CA	DO	CEO	6	S.d	-1,357	30.78	-44		640	D
10/8/25 16:05	10/6/25	TWST	Twist Bioscience Corp	DE	Health	BioPrd	Biological Products, (No Diag	Werner Robert F.	CA	O	Chief Ac	5	S	-107	30.07	-4		50	D
10/8/25 16:05	10/6/25	TWST	Twist Bioscience Corp	DE	Health	BioPrd	Biological Products, (No Diag	Green Paula	CA	O	SVP of H	6	S	-400	30.94	-13		126	D
10/8/25 16:05	10/6/25	TWST	Twist Bioscience Corp	DE	Health	BioPrd	Biological Products, (No Diag	Finn Patrick John	CA	O	P,COO	5	S	-988	31.66	-31		238	D
10/8/25 16:05	10/6/25	TWST	Twist Bioscience Corp	DE	Health	BioPrd	Biological Products, (No Diag	Cho Dennis	CA	O	See Rema	7	S	-180	30.48	-6		104	D
10/7/25 21:49	10/7/25	MGTX	Meiragtx Holdings Plc		Health	BioPrd	Biological Products, (No Diag	Forbes Alexandria	NY	DO	P,CEO	1	S	-399	8.39	-48		1,314	D
10/7/25 19:18	10/2/25	PLSE	Pulse Biosciences, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Danahy Kevin Patrick	CA	O	Chief Co	2	S.dm	-462	18.50	-25		43	D
10/7/25 18:29	10/3/25	CBLL	Ceribell, Inc.	DE	Health	ElcMd	Electromedical & Electrothera	Woo Raymond	CA	O	CTO	2	S.d	-274	12.33	-22		168	D
10/7/25 17:18	10/6/25	AXGN	Axogen, Inc.	MN	Health	ElcMd	Electromedical & Electrothera	Burke William P. Mr.	FL	D		2	S.m	-597	18.14	-33		2	D
10/7/25 17:08	9/9/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Malik Fady Ibraham	CA	O	EVP Rese	6	S.d	-547	45.54	-12		141	D
10/7/25 16:47	10/3/25	HIMS	Hims & Hers Health, Inc.	DE	Health	Health	Offices & Clinics of Doctors	Okupe Oluyemi	CA	O	CFO	6	S.d	-16,236	56.31	-288		137	D
10/7/25 16:30	10/3/25	VYGR	Voyager Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Jorgensen Nathan D.	MA	O	CFO	1	S	-37	4.78	-8		124	D
10/7/25 16:27	10/6/25	VCYT	Veracyte, Inc.	DE	Health	Health	Medical Laboratories	Febbo Phillip G.	CA	O	Chief Sc	1	S	-301	36.02	-8		92	D
10/7/25 16:26	10/3/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Allan Jonathan	MA	O	GC,Corp	4	S.dm	-932	19.61	-48		24	D
10/7/25 16:15	10/3/25	BBNX	Beta Bionics, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Feider Stephen	CA	O	CFO	7	S.d	-829	19.99	-41		46	D
10/7/25 16:11	10/3/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mosbrooker Eric	CA	O	Chief Co	3	S.d	-6,370	44.26	-144		55	D
10/6/25 20:00	10/2/25	NXGL	Nexgel, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Henry Scott Robert	PA	D		2	S.m	-39	2.45	-16		121	D
10/6/25 20:00	8/28/25	NXGL	Nexgel, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Levy Adam R.	PA	DO	CEO	2	S.m	-20	2.50	-8		372	D
10/6/25 18:22	10/6/25	FENC	Fennec Pharmaceuticals Inc.	A1	Health	BioPrd	Biological Products, (No Diag	Raykov Rosty	NC	D		3	S	-268	8.93	-30		83	D
10/6/25 18:10	10/2/25	SIBN	Si-Bone, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Pisetsky Michael A.	CA	O	SVP,Ops,	2	S	-97	14.97	-6		258	D
10/6/25 18:10	10/2/25	SIBN	Si-Bone, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Maheshwari Anshul	CA	O	CFO	3	S.a	-117	15.30	-8		218	D
10/6/25 18:09	8/18/25	SIBN	Si-Bone, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Recupero Anthony J	CA	O	P,Commer	2	S	-107	14.99	-7		275	D
10/6/25 17:13	10/2/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	Kaiser Peter	MA	O	Chief De	2	S	-143	11.27	-13		204	D
10/6/25 17:10	10/2/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	Heier Jeffrey S.	MA	O	Chief Sc	2	S	-153	11.27	-14		260	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Lee Kevin	X0	DO	CEO	1	S.m	-46	8.41	-5		475	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Skynner Michael	X0	O	CTO	1	S.m	-15	8.41	-2		118	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Milnes Alistair	X0	O	COO	1	S.m	-18	8.40	-2		93	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Hannay Michael Charles Ferguson	X0	O	CHIEF PR	1	S.m	-6	8.40	-1		53	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Young Alethia	X0	O	CFO	1	S	-4	8.51	0		45	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Thompson Travis Alvin	X0	O	Chief Ac	1	S.m	-3	8.40	0		31	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Swanton Robert Charles	X0	D		1	S	-1	8.55	0		15	D
10/6/25 16:15	9/5/25	SERA	Sera Prognostics, Inc.	DE	Health	Health	Medical Laboratories	Mirza Mansoor Raza	UT	D		3	S	-2	3.00	-1		59	D
10/6/25 16:11	10/2/25	CSTL	Castle Biosciences Inc	DE	Health	Health	Medical Laboratories	Maetzold Derek J	TX	DO	P,Chief	5	S	-958	19.79	-48		331	D
10/6/25 15:15	10/2/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Edwards Larry Todd	CA	O	See Rema	1	S	-90	20.04	-5		179	D
10/3/25 21:58	10/2/25	ELTP	Elite Pharmaceuticals Inc /Nv/	NJ	Health	Drug	Pharmaceutical Preparations	Plassche Douglas	NJ	O	EVP Oper	1	S	-499	0.6240	-800		3,500	D
10/3/25 21:27	9/2/25	JAZZ	Jazz Pharmaceuticals Plc	L2	Health	Drug	Pharmaceutical Preparations	Cozadd Bruce C	L2	D		3	S.m	-1,638	131.08	-13		436	D
10/3/25 20:00	10/1/25	APGE	Apogee Therapeutics, Inc.		Health	BioPrd	Biological Products, (No Diag	Dambkowski Carl	MA	O	Chief Me	3	S.d	-410	38.78	-11		285	D
10/3/25 19:32	10/2/25	PEN	Penumbra Inc	DE	Health	MdEq	Surgical & Medical Instrument	Grewal Harpreet	CA	D		2	S	-97	260.40	0		9	D
10/3/25 19:31	10/1/25	PEN	Penumbra Inc	DE	Health	MdEq	Surgical & Medical Instrument	Roberts Johanna	CA	O	EVP,Gen.	3	S	-456	253.07	-2		65	D
10/3/25 19:30	10/1/25	PEN	Penumbra Inc	DE	Health	MdEq	Surgical & Medical Instrument	Wilder Thomas	CA	D		2	S	-137	244.75	-1		5	D
10/3/25 19:00	9/2/25	ATEC	Alphatec Holdings, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Miles Patrick	CA	DO	CEO	2	S	-6,115	15.29	-400		5,825	D
10/3/25 18:15	10/1/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hamilton James C	CA	O	Chief Me	4	S.m	-1,725	28.75	-60		262	D
10/3/25 18:00	10/1/25	HALO	Halozyme Therapeutics, Inc.	DE	Health	BioPrd	Biological Products, (No Diag	Torley Helen	CA	DO	P,CEO	3	S.dm	-12,574	69.85	-180		734	D
10/3/25 17:53	10/2/25	SGHT	Sight Sciences, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Bauerlein Alison	CA	O	CFO	1	S	-66	3.30	-20		598	D
10/3/25 17:53	10/1/25	SGHT	Sight Sciences, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Badawi Paul	CA	DOT	P,CEO	1	S	-82	3.34	-24	0	5,963	D
10/3/25 17:53	10/3/25	SGHT	Sight Sciences, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Badawi David	CA	DO	CTO	1	S	-20	3.27	-6	0	1,865	D
10/3/25 17:52	10/3/25	SGHT	Sight Sciences, Inc.	DE	Health	MdEq	Surgical & Medical Instrument	Hayden Jeremy B.	CA	O	GC	1	S	-32	3.27	-10		257	D
10/3/25 17:50	10/1/25	WRBY	Warby Parker Inc.	DE	Health	OthMd	Ophthalmic Goods	Gilboa David Abraham	NY	DO	Co-CEO	4	S.dm	-7,989	26.63	-300		33	D
10/3/25 17:24	10/1/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Belanoff Joseph K	CA	DO	CEO	3	S	-8,965	74.71	-120		2,861	I
10/3/25 17:17	10/1/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Lyon Joseph Douglas	CA	O	See Rema	3	S.d	-1,168	73.83	-16		10	D
10/3/25 17:15	10/1/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Maduck Sean	CA	O	See Rema	3	S.d	-5,484	73.12	-75		118	D
10/3/25 17:14	10/2/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Poulton Jeffrey V.	MA	O	EVP,CFO	2	S	-2,758	452.50	-6		54	D
10/3/25 17:14	10/2/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Greenstreet Yvonne	MA	DO	CEO	2	S	-7,197	452.58	-16		66	D
10/3/25 17:14	10/2/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Tanguler Tolga	MA	O	EVP,Chie	3	S	-2,826	450.28	-6		29	D
10/3/25 17:13	10/1/25	NTLA	Intellia Therapeutics, Inc.	DE	Health	Diagn	In Vitro & In Vivo Diagnostic	Schultes Birgit C	MA	O	EVP,Chie	1	S	-1	17.39	0	0	105	D
10/3/25 17:13	10/2/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Fitzgerald Kevin Joseph	MA	O	CSO,EVP,	2	S	-1,736	452.49	-4		26	D
10/3/25 17:13	10/1/25	NTLA	Intellia Therapeutics, Inc.	DE	Health	Diagn	In Vitro & In Vivo Diagnostic	Dube Michael P	MA	O	VP,Chief	1	S	-33	17.38	-2		55	D
10/3/25 17:12	10/2/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Garg Pushkal	MA	O	EVP Chie	2	S.m	-3,992	453.10	-9		21	D
10/3/25 17:02	10/1/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Watanabe Todd	CA	DO	See Rema	3	S.m	-1,228	18.41	-67		1,135	D
10/3/25 17:01	10/1/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Welgus Howard G.	CA	D		3	S.d	-489	16.29	-30		100	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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