Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	Title	#f	T	TVal	Price	Qty	oc	Own	H
9/3/25 06:04	8/28/25	SPRO	Spero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mahadevia Ankit	MA	D		1	S	-13	1.97	-7		703	D
9/3/25 06:02	8/28/25	SPRO	Spero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Keutzer Timothy	MA	O	COO	1	S	-3	1.97	-2	0	740	D
9/2/25 21:52	8/25/25	STTK	Shattuck Labs, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D		2	P.d	10,364	1.39	7,482	999%	8,216	I
9/2/25 21:50	8/25/25	STTK	Shattuck Labs, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ashiya Mona	TX	D		1	P.d	5,472	0.8677	6,306		1,051	I
9/2/25 20:30	9/2/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gallagher Kathleen P.	CA	O	Chief Pr	2	S	-36	33.18	-1		50	D
9/2/25 19:46	8/28/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Manning Paul B	VA	D		1	S.m	-18,957	28.26	-671		5,950	I
9/2/25 19:11	9/2/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jeffs Roger	NY	D		7	S.dm	-13,952	78.24	-178		2,758	D
9/2/25 19:00	8/31/25	BTAI	Bioxcel Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mack David J.	CT	D		3	M.d	0	0.00	5	43	17	D
9/2/25 17:03	7/11/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Adair Jason	NC	O	Chief Bu	5	M.dm	785	20.93	37	24	194	D
9/2/25 17:03	8/28/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Adair Jason	NC	O	Chief Bu	5	S.dm	-785	20.93	-37		194	D
9/2/25 17:02	8/28/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Saggar Rajeev	NC	O	Chief Me	4	S.d	-670	21.34	-31		271	D
9/2/25 16:41	8/18/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Kaye Edward M. Md	CA	D		3	S.d	-559	12.38	-45		189	D
9/2/25 16:39	7/25/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Causey Christopher	MD	D		3	M.d	1,667	231.78	7		5	D
9/2/25 16:34	9/2/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Harrington Robert Arthur	CA	D		1	S	-105	48.67	-2		20	D
9/2/25 16:31	9/2/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Blum Robert I	CA	DO	P,CEO	6	S	-1,146	38.19	-30		407	D
9/2/25 16:10	8/29/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Tanguler Tolga	MA	O	EVP,Chie	2	S	-2,190	449.78	-5		29	D
9/2/25 13:05	8/28/25	CALC	Calcimedica, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Roberts Eric W	CA	DOT	CHIEF BU	13	P.dm	158	2.17	73	7	1,050	I
8/29/25 20:35	8/27/25	CVKD	Cadrenal Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Szot Matthew K	FL	O	CFO	1	S.m	-28	14.00	-2		31	D
8/29/25 20:34	8/27/25	CVKD	Cadrenal Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pham Quang X	FL	DOT	CEO,CB	1	S.m	-70	13.99	-5		413	D
8/29/25 18:46	8/22/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Hariri Robert J	TN	D		1	S	-43	8.60	-5		26	D
8/29/25 17:30	8/27/25	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	Waddill William D.	CA	D		1	S	-237	59.25	-4		9	D
8/29/25 17:21	8/28/25	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	Sherman Jeffrey W	IL	D		2	M.d	648	7.26	89	66	225	D
8/29/25 17:21	8/28/25	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	Sherman Jeffrey W	IL	D		2	S.d	-648	7.26	-89		225	D
8/29/25 17:03	8/27/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hohl Benjamin	CO	O	CFO	10	M.d	326	11.85	28		23	D
8/29/25 17:03	8/27/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hohl Benjamin	CO	O	CFO	10	S.d	-326	11.85	-28		23	D
8/29/25 16:55	8/21/25	AKTX	Akari Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Gaslightwala Abizer	MA	DO	CEO	4	P.m	57	1.09	52	21	299	D
8/29/25 16:28	8/28/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Boyce Sarah	CA	DO	P,CEO	2	M.d	1,266	25.31	50	20	306	D
8/29/25 16:28	8/28/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Boyce Sarah	CA	DO	P,CEO	2	S.d	-1,266	25.31	-50		306	D
8/29/25 16:21	8/19/25	PGEN	Precigen, Inc.	VA	Health	Drug	Pharmaceutical Preparations	Agee Nancy H	MD	D		2	P.dm	99	0.6457	153	305	203	D
8/29/25 16:19	8/27/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Francois Cedric	MA	DO	CEO	5	S.dm	-9,888	21.54	-459		1,882	I
8/29/25 16:09	8/27/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Scadden David	MA	D		5	M.d	93	17.47	5	43	18	D
8/29/25 16:09	8/27/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Scadden David	MA	D		5	S.d	-93	17.47	-5		18	D
8/29/25 16:05	8/6/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Khattar Jack A.	MD	DO	P,CEO	8	M.dm	11,957	27.27	439	26	2,098	D
8/29/25 16:05	8/6/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Khattar Jack A.	MD	DO	P,CEO	8	S.dm	-11,957	27.27	-439		2,098	D
8/29/25 16:05	8/27/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Newhall Charles W III	MD	D		3	S	-270	45.01	-6		134	D
8/29/25 16:05	8/28/25	AARD	Aardvark Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lee Tien-Li	CA	DOT	CEO	1	M.d	73	4.24	17	1	2,987	D
8/29/25 16:02	8/27/25	VRTX	Vertex Pharmaceuticals Inc / Ma	MA	Health	Drug	Pharmaceutical Preparations	Bhatia Sangeeta N.	MA	D		1	S	-103	386.69	0		5	D
8/28/25 20:39	8/26/25	BYSI	Beyondspring Inc.		Health	Drug	Pharmaceutical Preparations	Decheng Capital China Life Sciences Usd Fund Iii, L.P.	CA	T		5	S.m	-1,340	2.89	-464		4,488	I
8/28/25 19:32	8/26/25	QTTB	Q32 Bio Inc.	DE	Health	Drug	Pharmaceutical Preparations	Morrison Jodie Pope	MA	DO	CEO	1	S	-19	1.80	-10		122	D
8/28/25 19:30	8/26/25	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Williams Laura A	MA	O	Chief Pa	3	M.d	576	4.23	136	52	396	D
8/28/25 19:30	8/26/25	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Williams Laura A	MA	O	Chief Pa	3	S.d	-576	4.23	-136		396	D
8/28/25 19:29	8/21/25	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kelliher Mike	MA	O	Chief Bu	1	S	-32	5.93	-5		277	D
8/28/25 19:28	8/26/25	QTTB	Q32 Bio Inc.	DE	Health	Drug	Pharmaceutical Preparations	Violette Shelia M.	MA	O	Chief Sc	1	S	-5	1.80	-3		95	D
8/28/25 19:20	8/26/25	QTTB	Q32 Bio Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kalowski Lee	MA	O	CFO,P	1	S	-8	1.80	-4		49	D
8/28/25 17:40	8/26/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cloonan Michael	MA	DO	P,CEO	4	M.dm	1,499	14.99	100	22	547	D
8/28/25 17:40	8/26/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cloonan Michael	MA	DO	P,CEO	4	S.dm	-1,499	14.99	-100		547	D
8/28/25 17:40	8/26/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ridloff Elena	MA	O	CFO,Head	2	S.m	-1,726	22.89	-75		72	D
8/28/25 17:00	8/27/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tierney David S	FL	D		2	M.d	637	8.38	76	25	380	D
8/28/25 17:00	8/27/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tierney David S	FL	D		2	S.d	-637	8.38	-76		380	D
8/28/25 17:00	8/26/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Miller Steve	FL	O	Chief Op	2	M.dm	2,836	8.34	340	47	1,060	D
8/28/25 17:00	8/26/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Miller Steve	FL	O	Chief Op	2	S.dm	-2,836	8.34	-340		1,060	D
8/28/25 17:00	8/26/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Daly Richard J	FL	DO	P,CEO	2	M.d	586	8.03	73	47	227	D
8/28/25 17:00	8/26/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Daly Richard J	FL	DO	P,CEO	2	S.d	-586	8.03	-73		227	D
8/28/25 16:56	8/26/25	RLMD	Relmada Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Traversa Sergio	FL	DO	CEO	1	P.m	178	0.6696	266	36	1,000	D
8/28/25 16:55	8/26/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Russell Alan J	CO	DO	Chief Sc	4	M.d	1,503	7.24	208		23	D
8/28/25 16:55	8/26/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Russell Alan J	CO	DO	Chief Sc	4	S.d	-1,503	7.24	-208		23	D
8/28/25 16:25	8/27/25	AMRX	Amneal Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Kiely John	NJ	D		1	S	-295	9.23	-32		225	D
8/28/25 16:14	8/28/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	Zakrowski Donald A	IN	O	SVP,Fina	1	S	-735	734.93	-1		6	D
8/28/25 16:05	8/27/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	Cline Christopher R.	CA	O	CFO	1	S	-8	17.31	0		93	D
8/27/25 20:54	8/27/25	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bjork Elisabeth	NJ	D		1	P	34	3.41	10	33	40	D
8/27/25 18:44	8/25/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	Kaiser Peter	MA	O	Chief De	1	S	-36	12.04	-3		204	D
8/27/25 18:43	8/25/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	Nayak Sanjay	MA	O	Chief St	1	S	-23	12.04	-2		280	D
8/27/25 18:42	8/25/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	Heier Jeffrey S.	MA	O	Chief Sc	1	S	-37	12.04	-3		260	D
8/27/25 18:41	8/25/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	Dugel Pravin	MA	DO	See Rema	1	S	-259	12.04	-21		3,478	D
8/27/25 17:16	8/18/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	Moreadith Randall	AL	O	Chief Sc	20	M.dm	624	3.13	199		0	D
8/27/25 17:16	8/18/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	Moreadith Randall	AL	O	Chief Sc	20	S.dm	-624	3.13	-199	-100	0	D
8/27/25 17:08	8/25/25	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	Kooij Louise Frederika	P7	O	Chief Ac	1	S	-206	24.86	-8		15	D
8/27/25 17:01	8/25/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bhatt Padmanabh P.	MD	O	SVP of I	1	M.d	0	0.00	1	10	14	D
8/27/25 16:59	8/25/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mottola Frank	MD	O	SVP,Qual	2	M.d	805	28.75	28		15	D
8/27/25 16:59	8/25/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mottola Frank	MD	O	SVP,Qual	2	S.d	-805	28.75	-28		15	D
8/27/25 16:30	8/25/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Noci Darlene	MA	O	Chief De	6	M.d	1,269	52.87	24	100	48	D
8/27/25 16:30	8/25/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Noci Darlene	MA	O	Chief De	6	S.d	-1,269	52.87	-24		48	D
8/26/25 21:54	8/25/25	DERM	Journey Medical Corp	DE	Health	Drug	Pharmaceutical Preparations	Maraoui Claude	AZ	DO	P,CEO	1	M.d	81	0.0650	1,250	110	2,387	D
8/26/25 21:40	8/22/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	Verdine Gregory L.	MA	D		2	S	-309	7.71	-40		285	D
8/26/25 21:40	8/22/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	Bolno Paul	MA	DO	P,CEO	1	S	-2,195	10.10	-217		121	D
8/26/25 20:00	8/22/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sweeny Nicole	MA	O	Chief Co	4	M.d	45	3.05	15	82	32	D
8/26/25 20:00	8/25/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sweeny Nicole	MA	O	Chief Co	4	S.d	-45	3.05	-15		32	D
8/26/25 19:59	8/22/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yea Christopher	MA	O	Chief De	7	M.d	567	11.74	48	58	132	D
8/26/25 19:59	8/25/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yea Christopher	MA	O	Chief De	7	S.d	-567	11.74	-48		132	D
8/26/25 19:57	8/22/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Audhya Paul K.	MA	O	Chief Me	6	M.d	109	4.21	26	27	123	D
8/26/25 19:57	8/25/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Audhya Paul K.	MA	O	Chief Me	6	S.d	-109	4.21	-26		123	D
8/26/25 18:56	8/22/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Robb Gary Charles	CA	O	Chief Bu	3	M.d	411	39.06	11	40	37	D
8/26/25 18:56	8/22/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Robb Gary Charles	CA	O	Chief Bu	3	S.d	-411	39.06	-11		37	D
8/26/25 18:26	8/22/25	EOLS	Evolus, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yamagishi-Dressler Tomoko	CA	O	CMO	1	S	-43	7.51	-6		90	D
8/26/25 18:19	8/25/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Leonard Matthew J	MN	D		2	S	-841	88.82	-9		9	D
8/26/25 18:01	8/22/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bitterman Kevin	MA	D		6	S.m	-5,305	61.06	-87		1,148	I
8/26/25 17:23	8/22/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Diaz Allene M.	CA	D		2	S.d	-61	11.02	-6		20	D
8/26/25 17:17	8/22/25	ELTP	Elite Pharmaceuticals Inc /Nv/	NJ	Health	Drug	Pharmaceutical Preparations	Elite Pharmaceuticals Inc /Nv/	NJ	O	EVP Oper	2	S.d	-337	0.1124	-3,000		4,300	D
8/26/25 17:17	8/25/25	ELTP	Elite Pharmaceuticals Inc /Nv/	NJ	Health	Drug	Pharmaceutical Preparations	Elite Pharmaceuticals Inc /Nv/	NJ	O	EVP Oper	2	M.d	337	0.1124	3,000	231	4,300	D
8/26/25 16:30	8/22/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pizzuti Dana	CA	O	Chief Me	3	M.d	1,609	24.20	66		66	D
8/26/25 16:30	8/22/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pizzuti Dana	CA	O	Chief Me	3	S.d	-1,609	24.20	-66		66	D
8/26/25 16:18	8/22/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dec Timothy C	MD	O	Senior V	1	S	-524	44.49	-12		1	D
8/26/25 16:15	8/22/25	TNGX	Tango Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Third Rock Ventures Iv, L.P.	MA	T		2	S	-9,828	7.01	-1,402		15,759	D
8/26/25 15:41	8/22/25	DRRX	Durect Corp	DE	Health	Drug	Pharmaceutical Preparations	Asen R Scott	NY	T		2	P.m	398	1.89	210	6	3,643	D
8/26/25 06:10	8/22/25	RNXT	Renovorx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bagai Shaun	CA	DO	CEO	1	P.m	9	0.9297	10	3	330	D
8/25/25 21:12	8/21/25	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Renz Justin A	MA	O	CFO	1	S	-42	5.93	-7		409	D
8/25/25 21:08	8/21/25	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Raab Michael	MA	DO	P,CEO	1	S	-271	5.93	-46		1,528	D
8/25/25 21:03	8/21/25	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Grammer Elizabeth A	MA	O	See Rema	1	S	-35	5.93	-6		306	D
8/25/25 21:02	8/21/25	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Foster Eric Duane	MA	O	Chief Co	1	S	-91	5.93	-15		301	D
8/25/25 20:59	8/21/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Shulman Joseph	MA	O	Chief Te	6	M.d	1,594	49.37	32		9	D
8/25/25 20:59	8/21/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Shulman Joseph	MA	O	Chief Te	6	S.d	-1,594	49.37	-32		9	D
8/25/25 19:46	8/21/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Palleiko Benjamin L	MA	DO	CEO	7	M.d	824	7.95	104	37	387	D
8/25/25 19:46	8/22/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Palleiko Benjamin L	MA	DO	CEO	7	S.d	-824	7.95	-104		387	D
8/25/25 19:12	8/22/25	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	Duato Joaquin	NJ	DO	CEO,CB	2	M.d	35,366	140.54	252	161	408	D
8/25/25 19:12	8/22/25	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	Duato Joaquin	NJ	DO	CEO,CB	2	S.d	-35,366	140.54	-252		408	D
8/25/25 17:04	8/21/25	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	Kastelein Johannes Jacob Pieter	P7	DO	Chief Sc	1	S.m	-2,472	24.72	-100		69	I
8/25/25 16:27	8/22/25	AMRX	Amneal Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Shah Nikita	NJ	O	EVP	3	S.m	-2,284	9.42	-243		339	D
8/25/25 16:19	8/22/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Davis Krista	MN	O	SVP,CHRO	1	S	-161	91.10	-2		63	D
8/25/25 08:50	8/22/25	DVAX	Dynavax Technologies Corp	DE	Health	Drug	Pharmaceutical Preparations	Myers Scott Dunseth	CA	D		1	P	41	10.82	4	12	35	D
8/22/25 21:00	8/20/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Venker Eric	X0	O	P,Immuno	6	M.d	4,624	7.71	600	57	1,654	D
8/22/25 21:00	8/20/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Venker Eric	X0	O	P,Immuno	6	S.d	-4,624	7.71	-600		1,654	D
8/22/25 20:49	8/21/25	DVAX	Dynavax Technologies Corp	DE	Health	Drug	Pharmaceutical Preparations	Deep Track Biotechnology Master Fund, Ltd.	E9	T		1	S.m	-22,352	10.82	-2,065		15,726	D
8/22/25 19:07	8/21/25	SKYE	Skye Bioscience, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Schwab Andrew J.	CA	DT		1	S.m	-801	3.46	-231		9,682	I
8/22/25 19:05	8/21/25	SKYE	Skye Bioscience, Inc.	NV	Health	Drug	Pharmaceutical Preparations	5Am Partners Vii, LLC	CA	T		1	S.m	-801	3.46	-231		9,682	I
8/22/25 18:10	8/20/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Shanmugam Muthusamy	MN	DO	HEAD OF	2	S.m	-17,861	89.30	-200		630	I
8/22/25 17:20	8/22/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hughes Steven George	CA	O	Chief Me	6	M.d	4,266	31.28	136		39	D
8/22/25 17:20	8/22/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hughes Steven George	CA	O	Chief Me	6	S.d	-4,266	31.28	-136		39	D
8/22/25 16:58	8/21/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Trimarchi Thomas	CA	O	P,CFO	2	S	-2,962	49.70	-60		463	D
8/22/25 16:46	8/20/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kumar Neil	CA	DO	CEO	4	S.dm	-8,354	33.30	-251		5,932	D
8/22/25 16:38	8/12/25	AMRX	Amneal Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Boyer Andrew S	NJ	O	EVP	3	S.d	-3,403	6.98	-488		257	D
8/22/25 16:32	8/21/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	12	M.d	28,505	215.95	132		37	D
8/22/25 16:32	8/21/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	12	S.d	-28,505	215.95	-132		37	D
8/22/25 16:30	8/21/25	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lowenthal Richard E	CA	DOT	P,CEO	1	S	-724	14.49	-50	0	11,303	I
8/22/25 16:30	8/21/25	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Scott Kathleen D.	CA	O	CFO	2	M.d	206	8.25	25		18	D
8/22/25 16:30	8/21/25	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Scott Kathleen D.	CA	O	CFO	2	S.d	-206	8.25	-25		18	D
8/22/25 16:19	8/21/25	BHC	Bausch Health Companies Inc.	NJ	Health	Drug	Pharmaceutical Preparations	Lee Frank D.	NJ	D		1	S	-122	7.66	-16		74	D
8/22/25 16:07	8/21/25	LYEL	Lyell Immunopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Seely Lynn	CA	DO	P,CEO	2	S.m	-85	10.53	-8		68	D
8/22/25 16:06	8/21/25	LYEL	Lyell Immunopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hill Stephen J.	CA	O	COO	2	S.m	-13	10.53	-1		16	D
8/22/25 16:03	8/21/25	LYEL	Lyell Immunopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Newton Charles W.	CA	O	CFO	2	S.m	-18	10.53	-2		25	D
8/22/25 16:02	8/21/25	LYEL	Lyell Immunopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lee Gary K.	CA	O	Chief Sc	2	S.m	-18	10.53	-2		16	D
8/22/25 13:27	8/22/25	PRGO	Perrigo Co Plc	L2	Health	Drug	Pharmaceutical Preparations	Willis Robert	MI	O	EVP,CHRO	1	P	36	24.10	1	4	42	D
8/21/25 21:32	8/19/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Burnett Patrick	CA	O	See Rema	5	S.dm	-591	8.66	-68		115	D
8/21/25 21:05	8/19/25	NKTR	Nektar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	Zalevsky Jonathan	CA	O	Chief R,	1	S.d	-19	26.59	-1		20	D
8/21/25 21:04	8/19/25	NKTR	Nektar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	Wilson Mark Andrew	CA	O	GC	1	S.d	-18	26.59	-1		20	D
8/21/25 21:03	8/19/25	NKTR	Nektar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	Robin Howard W	CA	DO	P,CEO	1	S.d	-42	26.59	-2		69	D
8/21/25 20:44	8/21/25	CLNN	Clene Inc.	DE	Health	Drug	Pharmaceutical Preparations	General Resonance LLC	UT	T		1	S	-18	5.34	-3	0	705	D
8/21/25 18:48	8/20/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kintz Samuel	CO	DO	P,CEO	4	S.m	-809	21.57	-38		953	I
8/21/25 18:46	8/19/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lyssikatos Joseph P	CO	O	CHIEF SC	3	S.m	-794	21.18	-38		965	I
8/21/25 17:44	8/21/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sibold William John	PA	DO	P,CEO	1	S	-3,048	400.18	-8		110	D
8/21/25 17:36	8/19/25	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tanimoto Sarina	CA	OT	CHIEF ME	1	S.m	-704	14.08	-50	0	11,353	I
8/21/25 17:22	8/21/25	TNXP	Tonix Pharmaceuticals Holding Corp.	NV	Health	Drug	Pharmaceutical Preparations	Taylor Carolyn E.	NJ	D		1	P	15	36.03	0		0	D
8/21/25 17:07	8/20/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Sharoky Melvin Md	NJ	D		2	S	-2,511	125.54	-20		334	D
8/21/25 17:05	8/19/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Adsett Roger	NJ	O	COO	2	S	-4,246	118.97	-36		131	D
8/21/25 17:00	8/19/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Stefanovich Robert	TN	O	CFO	2	M.d	161	4.54	35	21	207	D
8/21/25 17:00	8/19/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Stefanovich Robert	TN	O	CFO	2	S.d	-161	4.54	-35		207	D
8/21/25 16:30	8/19/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Horobin Joanna	NC	D		1	S	-136	27.17	-5		34	D
8/21/25 16:19	8/19/25	MGNX	Macrogenics Inc	DE	Health	Drug	Pharmaceutical Preparations	Heiden William K	MD	D		1	P.m	151	1.51	100	909	111	D
8/21/25 12:00	8/19/25	CALC	Calcimedica, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hebbar Sudarshan	CA	O	Chief Me	2	P.m	43	2.79	16	34	62	D
8/20/25 18:14	8/18/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	EVP,Chie	2	M.d	766	38.29	20	27	93	D
8/20/25 18:14	8/18/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	EVP,Chie	2	S.d	-766	38.29	-20		93	D
8/20/25 18:12	8/18/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Baker Bros. Advisors LP	NY	D		2	P.m	61,921	373.73	166	9	1,948	I
8/20/25 17:14	8/19/25	ETON	Eton Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gruber James R.	IL	O	CFO	1	S.m	-674	16.15	-42		205	D
8/20/25 17:00	8/18/25	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Militello John	NJ	O	See Rema	2	S.m	-24	3.02	-8		57	D
8/20/25 17:00	8/18/25	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Schwartz Jonathan David	NJ	O	See Rema	2	S.m	-41	3.02	-14		224	D
8/20/25 17:00	8/18/25	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Wilson Martin	NJ	O	GC	2	S.m	-41	3.02	-14		137	D
8/20/25 16:57	8/18/25	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	Dreyer Scott	MA	O	EVP,Chie	4	M.d	1,265	29.75	43	70	104	D
8/20/25 16:57	8/18/25	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	Dreyer Scott	MA	O	EVP,Chie	4	S.d	-1,265	29.75	-43		104	D
8/20/25 16:42	8/18/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Thoma Jeanne	MN	D		1	S	-1,920	89.15	-22		23	D
8/20/25 16:41	8/20/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Pera Antonio R	MN	D		1	S	-486	89.73	-5		30	D
8/20/25 16:38	8/19/25	ZVRA	Zevra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bode John B	FL	D		1	P	46	9.17	5	13	45	D
8/20/25 16:36	8/18/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Tessari Eben	X0	O	COO	10	M.dm	10,834	22.07	491		72	D
8/20/25 16:36	8/18/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Tessari Eben	X0	O	COO	10	S.dm	-10,834	22.07	-491		72	D
8/20/25 16:28	6/16/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Lewis William	NJ	DO	Chair,CE	10	S.d	-18,261	57.15	-320		588	M
8/20/25 16:28	6/16/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Lewis William	NJ	DO	Chair,CE	10	M.d	18,261	57.15	320	119	588	M
8/20/25 16:15	8/20/25	TNXP	Tonix Pharmaceuticals Holding Corp.	NV	Health	Drug	Pharmaceutical Preparations	Treco James	NJ	D		1	P	9	36.00	0		0	D
8/20/25 16:13	8/18/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ticho Barry	MA	O	Chief Me	4	S.d	-161	7.39	-22		27	D
8/20/25 16:11	8/18/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Allan Jonathan	MA	O	GC,Corp	3	S.d	-236	11.05	-21		26	D
8/20/25 16:04	8/19/25	GOSS	Gossamer Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Milligan Sandra	CA	D		1	P	50	1.92	26	81	58	D
8/20/25 16:02	8/18/25	ALXO	Alx Oncology Holdings Inc	DE	Health	Drug	Pharmaceutical Preparations	Shantharam Harish	CA	O	CFO	1	P	58	0.7787	75		75	D
8/20/25 16:01	8/15/25	ARCT	Arcturus Therapeutics Holdings Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sassine Andy	CA	DO	CFO	2	P	41	16.56	2	1	222	D
8/20/25 08:11	8/18/25	PRGO	Perrigo Co Plc	L2	Health	Drug	Pharmaceutical Preparations	Parker Geoffrey M.	MI	D		2	P	201	22.97	9	16	65	I
8/19/25 21:32	8/15/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gangloff Scott A.	CA	O	CTO	2	M.d	98	28.28	3	15	26	D
8/19/25 20:00	8/15/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	Tan Aik Na	MA	D		3	M.d	396	9.18	43		40	D
8/19/25 20:00	8/15/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	Tan Aik Na	MA	D		3	S.d	-396	9.18	-43		40	D
8/19/25 19:40	8/15/25	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	York Charles N II	CA	O	COO,CFO	2	M.d	28	1.32	21	8	278	D
8/19/25 19:40	8/18/25	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	York Charles N II	CA	O	COO,CFO	2	S.d	-28	1.32	-21		278	D
8/19/25 19:38	8/15/25	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dubow Adam	CA	O	GC,Secre	2	M.d	30	1.80	16	43	55	D
8/19/25 19:38	8/18/25	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dubow Adam	CA	O	GC,Secre	2	S.d	-30	1.80	-16		55	D
8/19/25 19:37	8/15/25	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bender Jeremy	CA	DO	CEO	2	M.d	109	2.28	48	3	1,770	D
8/19/25 19:37	8/18/25	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bender Jeremy	CA	DO	CEO	2	S.d	-109	2.28	-48		1,770	D
8/19/25 19:36	8/15/25	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Merendino Lauren	CA	O	Chief Co	2	M.d	25	1.78	14	52	42	D
8/19/25 19:36	8/18/25	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Merendino Lauren	CA	O	Chief Co	2	S.d	-25	1.78	-14		42	D
8/19/25 18:00	8/18/25	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Schneyer Mark C.	CA	O	EVP,CFO	1	S	-554	25.18	-22		40	D
8/19/25 17:28	8/18/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Garg Pushkal	MA	O	EVP Chie	1	S.m	-1,300	455.89	-3		21	D
8/19/25 17:27	8/18/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Poulton Jeffrey V.	MA	O	EVP,CFO	1	S	-1,031	453.27	-2		50	D
8/19/25 17:27	8/18/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Greenstreet Yvonne	MA	DO	CEO	1	S	-3,163	453.27	-7		57	D
8/19/25 17:26	8/18/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Fitzgerald Kevin Joseph	MA	O	CSO,EVP,	1	S	-633	453.27	-1		23	D
8/19/25 17:26	8/18/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Bonney Michael W	MA	D		2	M.d	5,852	260.10	23		21	D
8/19/25 17:26	8/18/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Bonney Michael W	MA	D		2	S.d	-5,852	260.10	-23		21	D
8/19/25 17:10	8/15/25	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	Santini Gino	MA	D		2	M.d	403	19.74	20	27	95	D
8/19/25 17:10	8/15/25	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	Santini Gino	MA	D		2	S.d	-403	19.74	-20		95	D
8/19/25 17:02	8/18/25	SEPN	Septerna, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Klein Uwe	CA	O	SVP,Biol	1	M.d	94	4.10	23	22	128	D
8/19/25 16:40	8/18/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Watson David O.	MA	O	GC	3	S	-331	22.04	-15		214	D
8/19/25 16:40	8/15/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Smiley Joshua L	MA	O	See Rema	2	M.d	241	10.68	23	42	77	D
8/19/25 16:40	8/18/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Smiley Joshua L	MA	O	See Rema	2	S.d	-241	10.68	-23		77	D
8/19/25 16:40	8/15/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Edmondson Frazor Titus III	MA	O	GC	4	M.d	281	10.31	27	183	42	D
8/19/25 16:40	8/18/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Edmondson Frazor Titus III	MA	O	GC	4	S.d	-281	10.31	-27		42	D
8/19/25 16:37	8/19/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Malik Fady Ibraham	CA	O	EVP Rese	10	M.d	464	23.18	20	17	141	D
8/19/25 16:37	8/19/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Malik Fady Ibraham	CA	O	EVP Rese	10	S.d	-464	23.18	-20		141	D
8/19/25 16:30	8/15/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Porter James Richard	MA	DO	P,CEO	6	M.d	8,109	50.06	162	186	249	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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