Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	#o	#f	T	TVal	Price	Qty	oc	Own	H
5/22/25 21:55	5/20/25	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	15	S.d	-3,323	4.00	-830		5,887	D
5/22/25 21:00	5/6/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	2	9	S.dm	-26,516	8.16	-3,251		53,660	D
5/22/25 18:31	5/20/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	9	S.dm	-40,663	53.72	-757		617	D
5/22/25 18:27	5/21/25	ATOS	Atossa Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P	17	0.7951	21	84	46	D
5/22/25 17:55	5/19/25	NTHI	Neonc Technologies Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	11	P.adm	3,973	23.41	170	1	16,360	D
5/22/25 17:20	5/20/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	7	20	P.dm	13,784	54.03	255	26	1,230	I
5/22/25 17:00	5/20/25	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	12	M.dm	6,436	8.44	763		323	D
5/22/25 17:00	5/20/25	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	12	S.dm	-6,436	8.44	-763		323	D
5/22/25 16:48	5/20/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	7	37	S.dm	-54,884	53.64	-1,023		4,425	M
5/22/25 16:38	5/20/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	6	49	M.dm	12,920	17.40	742		433	D
5/22/25 16:38	5/20/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	6	49	S.dm	-12,920	17.40	-742		433	D
5/22/25 16:06	5/20/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	7	28	M.dm	20,488	4.81	4,260	15	32,457	D
5/22/25 16:06	5/20/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	7	28	S.dm	-20,488	4.81	-4,260		32,457	D
5/22/25 16:05	5/20/25	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	19	S.m	-854	8.08	-106		2,358	D
5/22/25 16:05	5/22/25	SLS	Sellas Life Sciences Group, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	36	1.80	20	95	41	D
5/22/25 16:03	5/20/25	MGNX	Macrogenics Inc	DE	Health	Drug	Pharmaceutical Preparations	9	9	M.d	0	0.00	59	80	132	D
5/22/25 16:01	5/20/25	GYRE	Gyre Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	18	S.dm	-1,212	1.58	-767		3,574	I
5/22/25 13:19	5/21/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	M.d	192	10.38	19	1	1,427	D
5/21/25 21:23	5/21/25	VNDA	Vanda Pharmaceuticals Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	10	P	472	4.63	102	4	2,718	D
5/21/25 20:08	5/19/25	NKTR	Nektar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-29	0.6700	-44		1,684	D
5/21/25 19:11	5/19/25	XOMA	Xoma Royalty Corp		Health	Drug	Pharmaceutical Preparations	4	9	M.dm	1,877	12.89	146	999%	155	D
5/21/25 19:11	5/20/25	XOMA	Xoma Royalty Corp		Health	Drug	Pharmaceutical Preparations	4	9	S.dm	-1,877	12.89	-146		155	D
5/21/25 18:31	5/19/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	20	S.dm	-1,801	16.15	-112		2,339	I
5/21/25 16:58	5/21/25	INO	Inovio Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	11	17	M.d	0	0.00	100	54	284	D
5/21/25 16:50	5/19/25	AEON	Aeon Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P.m	55	0.5027	110	114	207	D
5/21/25 16:33	5/19/25	BPMC	Blueprint Medicines Corp	DE	Health	Drug	Pharmaceutical Preparations	11	21	S.dm	-8,914	85.23	-105		805	D
5/21/25 16:13	5/20/25	PHIO	Phio Pharmaceuticals Corp.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	5	1.82	3	23	13	D
5/21/25 16:01	5/21/25	ZOMDF	Zomedica Corp.	A0	Health	Drug	Pharmaceutical Preparations	9	13	P	408	0.0636	6,425	34	25,429	D
5/21/25 12:57	5/20/25	MDCX	Medicus Pharma Ltd.	A6	Health	Drug	Pharmaceutical Preparations	1	1	S	-579	7.72	-75		3,249	I
5/20/25 21:46	5/20/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-322	107.49	-3		458	D
5/20/25 21:45	5/20/25	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.d	-590	4.65	-127		1,898	D
5/20/25 19:54	5/20/25	VSTM	Verastem, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	7	S.m	-582	8.10	-72		705	D
5/20/25 19:28	5/17/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	13	M.d	467	5.25	89	2	5,800	D
5/20/25 19:28	5/19/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	13	S.d	-467	5.25	-89		5,800	D
5/20/25 18:06	5/16/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	15	M.dm	17,878	29.09	615	10	6,652	M
5/20/25 18:06	5/19/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	15	S.dm	-17,878	29.09	-615		6,652	M
5/20/25 18:03	5/16/25	RLMD	Relmada Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	4	4	P.m	461	0.4712	979	135	1,703	D
5/20/25 17:58	5/20/25	BMRN	Biomarin Pharmaceutical Inc	DE	Health	Drug	Pharmaceutical Preparations	3	5	S	-810	69.00	-12		137	D
5/20/25 17:44	5/20/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	5	17	M.dm	9,299	12.23	760	156	1,247	D
5/20/25 17:44	5/20/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	5	17	S.dm	-9,299	12.23	-760		1,247	D
5/20/25 17:05	5/17/25	JAGX	Jaguar Health, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	M.d	0	0.00	0	0	1	D
5/20/25 16:37	5/19/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	19	S.dm	-2,691	13.25	-203		10,880	D
5/20/25 16:35	5/16/25	HCWB	Hcw Biologics Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	9	P.d	3,045	22.83	133	30	582	D
5/20/25 16:32	5/15/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	6	31	M.d	47,064	221.05	213		78	D
5/20/25 16:32	5/15/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	6	31	S.d	-47,064	221.05	-213		78	D
5/20/25 16:28	5/20/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	7	41	M.d	10,673	34.84	306	66	770	D
5/20/25 16:28	5/20/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	7	41	S.d	-10,673	34.84	-306		770	D
5/20/25 16:16	5/8/25	MTVA	Metavia Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	3,300	0.7100	4,648	87	9,996	D
5/20/25 16:14	5/16/25	IRWD	Ironwood Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-9	0.5800	-16		1,930	D
5/20/25 16:00	5/15/25	INZY	Inozyme Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	M.d	162	0.8476	191	70	465	D
5/19/25 20:52	5/16/25	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	3	19	S.d	-453	8.68	-52		104	D
5/19/25 19:06	5/15/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	28	M.dm	19,508	39.39	495	25	2,480	D
5/19/25 19:06	5/15/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	28	S.dm	-19,508	39.39	-495		2,480	D
5/19/25 18:35	5/15/25	ZYME	Zymeworks Inc.		Health	Drug	Pharmaceutical Preparations	1	8	P.m	26,071	12.05	2,164	14	17,884	I
5/19/25 18:30	5/19/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	S	-344	7.09	-48		153	D
5/19/25 17:54	5/15/25	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	M.d	167	1.71	98	5	2,102	D
5/19/25 17:54	5/16/25	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	S.d	-167	1.71	-98		2,102	D
5/19/25 17:33	4/4/25	OKUR	Onkure Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	5	S.m	-6,013	1.85	-3,242		4,670	D
5/19/25 17:07	5/15/25	VRTX	Vertex Pharmaceuticals Inc / Ma	MA	Health	Drug	Pharmaceutical Preparations	6	16	S	-14,820	491.38	-30		199	D
5/19/25 16:54	5/16/25	JBIO	Jade Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	44	7.40	6		6	D
5/19/25 16:44	3/26/25	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	6	20	P.d	5,284	4.42	1,196	19	7,549	I
5/19/25 16:30	5/15/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	5	S.m	-417	10.05	-42		485	D
5/19/25 16:17	5/15/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	9	23	M.dm	14,983	179.69	83	44	275	D
5/19/25 16:17	5/15/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	9	23	S.dm	-14,983	179.69	-83		275	D
5/19/25 16:16	5/16/25	AMRX	Amneal Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	16	28	S.dm	-47,454	5.55	-8,545		102,465	D
5/19/25 16:05	5/15/25	MCRB	Seres Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	M.d	3	1.71	2	8	27	D
5/19/25 16:05	5/16/25	MCRB	Seres Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	S.d	-3	1.71	-2		27	D
5/19/25 16:04	5/19/25	SNDX	Syndax Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	5	7	P.d	459	8.93	51	9	614	D
5/19/25 07:32	5/16/25	SRPT	Sarepta Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	11	M.d	1,286	9.79	131	4	3,455	D
5/16/25 20:07	3/14/25	PGEN	Precigen, Inc.	VA	Health	Drug	Pharmaceutical Preparations	12	12	M.d	0	0.00	2,339	1	190,540	I
5/16/25 18:00	5/16/25	LGVN	Longeveron Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-7	1.40	-5		722	D
5/16/25 17:59	5/14/25	XENE	Xenon Pharmaceuticals Inc.	A1	Health	Drug	Pharmaceutical Preparations	1	1	M.d	65	12.57	5	257	7	D
5/16/25 17:23	5/16/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-165	5.00	-33		1,448	D
5/16/25 16:57	3/19/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	5	11	S.d	-1,001	61.30	-16		1,080	D
5/16/25 16:30	5/15/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	13	M.dm	11,445	46.15	248	15	1,941	D
5/16/25 16:30	5/15/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	13	S.dm	-11,445	46.15	-248		1,941	D
5/16/25 16:15	5/15/25	THAR	Tharimmune, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	1	1.30	1		1	D
5/16/25 16:05	5/14/25	IGMS	Igm Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	5	S	-28	1.22	-23		622	D
5/16/25 11:53	5/14/25	PRGO	Perrigo Co Plc	L2	Health	Drug	Pharmaceutical Preparations	13	19	M.dm	3,909	26.54	147	57	407	D
5/16/25 11:28	5/13/25	LFCR	Lifecore Biomedical, Inc. De	DE	Health	Drug	Pharmaceutical Preparations	1	3	S.m	-738	7.04	-105		1,714	I
5/15/25 19:01	5/14/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	13	S.d	-38,757	13.45	-2,881		27,649	D
5/15/25 18:48	5/13/25	APUS	Apimeds Pharmaceuticals Us, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	P.dm	2,107	3.79	556	9	7,088	D
5/15/25 17:37	5/13/25	BGNE	Beigene, Ltd.		Health	Drug	Pharmaceutical Preparations	6	26	M.d	333,375	38.51	8,657	13	75,846	D
5/15/25 17:37	5/13/25	BGNE	Beigene, Ltd.		Health	Drug	Pharmaceutical Preparations	6	26	S.d	-333,375	38.51	-8,657		75,846	D
5/15/25 17:08	5/15/25	TNXP	Tonix Pharmaceuticals Holding Corp.	NV	Health	Drug	Pharmaceutical Preparations	1	1	P	86	21.55	4	999%	4	D
5/15/25 17:00	5/13/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	7	M.dm	14,346	13.11	1,094		257	D
5/15/25 17:00	5/13/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	7	S.dm	-14,346	13.11	-1,094		257	D
5/15/25 16:43	5/14/25	NGNE	Neurogene Inc.		Health	Drug	Pharmaceutical Preparations	2	2	S	-179	15.87	-11		93	D
5/15/25 16:27	5/13/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	8	33	M.dm	16,130	15.87	1,016		770	D
5/15/25 16:27	5/13/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	8	33	S.dm	-16,130	15.87	-1,016		770	D
5/15/25 16:17	5/13/25	PHAT	Phathom Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	P.dm	351	4.05	87	1	6,106	I
5/15/25 16:17	3/3/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	5	8	S.ed	-549,760	897.75	-612		96,608	D
5/15/25 16:09	3/31/25	OGN	Organon & Co.		Health	Drug	Pharmaceutical Preparations	11	16	M.d	652	1.72	379	80	851	D
5/15/25 16:02	5/13/25	EBS	Emergent Biosolutions Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	P	611	5.82	105	27	488	D
5/14/25 21:55	5/12/25	KTTA	Pasithea Therapeutics Corp.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-1	0.8250	-1		40	D
5/14/25 19:27	5/12/25	EOLS	Evolus, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	9	S	-2,419	12.76	-190		1,179	D
5/14/25 18:08	5/12/25	HOWL	Werewolf Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	P.dm	496	0.9105	545	3	20,919	I
5/14/25 18:03	5/12/25	ASRT	Assertio Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	M.d	0	0.00	166	44	541	D
5/14/25 18:00	5/12/25	VTRS	Viatris Inc	DE	Health	Drug	Pharmaceutical Preparations	16	18	P.dm	536	0.2628	2,040	265	2,812	D
5/14/25 17:00	5/12/25	ALZN	Alzamend Neuro, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	9	S.d	-33	0.8711	-38		238	M
5/14/25 16:56	5/12/25	HROW	Harrow, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	9	S.dm	-1,129	0.7915	-1,426		7,805	I
5/14/25 16:15	5/12/25	RNAC	Cartesian Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	M.dm	2,943	11.59	254	3	9,686	D
5/14/25 16:11	5/14/25	CRVO	Cervomed Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	36	8.46	4	334	6	D
5/13/25 20:05	5/9/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	3	4	P.d	1,858	100.87	18	9	222	D
5/13/25 19:03	5/9/25	BMY	Bristol Myers Squibb Co	DE	Health	Drug	Pharmaceutical Preparations	13	16	S.d	-206	0.6162	-334		1,009	I
5/13/25 18:51	5/9/25	JAZZ	Jazz Pharmaceuticals Plc	L2	Health	Drug	Pharmaceutical Preparations	5	10	P.dm	14,668	107.90	136	8	1,885	I
5/13/25 18:36	5/12/25	NVCT	Nuvectis Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	3	P.m	655	8.59	76	3	2,943	I
5/13/25 17:52	5/13/25	LXRX	Lexicon Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	12	12	M.d	0	0.00	785	2	47,425	D
5/13/25 17:05	5/12/25	GNLX	Genelux Corp	DE	Health	Drug	Pharmaceutical Preparations	5	5	S	-78	2.92	-27		374	D
5/13/25 16:20	2/27/25	GERN	Geron Corp	DE	Health	Drug	Pharmaceutical Preparations	4	4	P	222	1.58	141	103	277	D
5/13/25 16:11	5/9/25	LFVN	Lifevantage Corp		Health	Drug	Pharmaceutical Preparations	5	5	P.d	26	1.90	14	2	705	M
5/12/25 21:30	5/7/25	PTN	Palatin Technologies Inc	NJ	Health	Drug	Pharmaceutical Preparations	1	1	P	10	0.1018	100	263	138	D
5/12/25 20:50	5/8/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	5	5	P	272	6.89	39	1	4,453	D
5/12/25 16:15	5/9/25	BSPK	Bespoke Extracts, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	1	P.m	0	0.1050	2	0	2,495	D
5/12/25 16:14	5/8/25	MAIA	Maia Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	8	P.d	587	1.50	392	27	1,860	D
5/12/25 16:00	5/8/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	8	29	S.dm	-13,166	6.83	-1,926		1,417	D
5/9/25 21:30	5/7/25	OSTX	Os Therapies Inc	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.m	-245	1.73	-142		2,770	I
5/9/25 17:05	4/1/25	CPIX	Cumberland Pharmaceuticals Inc		Health	Drug	Pharmaceutical Preparations	4	8	P.m	13	4.82	3	0	6,059	D
5/9/25 16:15	5/8/25	FULC	Fulcrum Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-3	5.06	0		14	D
5/9/25 16:09	5/7/25	CRVS	Corvus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	1,957	3.50	559	32	2,325	D
5/9/25 16:07	5/1/25	HRMY	Harmony Biosciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	5	M.d	426	8.45	50		17	D
5/7/25 21:10	5/1/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	18	M.d	20,271	19.27	1,052	285	1,421	D
5/7/25 21:10	5/2/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	18	S.d	-20,271	19.27	-1,052		1,421	D
5/7/25 17:03	5/6/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	9	S	-166	6.27	-27		205	D
5/7/25 11:48	9/24/24	ERNA	Ernexa Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	P.d	394	0.0232	17,021	503	20,402	D
5/6/25 21:48	5/2/25	ALMS	Alumis Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	6	P.m	2,314	4.73	489	1	49,306	I
5/6/25 19:06	12/18/24	PRTA	Prothena Corp Public Ltd Co	L2	Health	Drug	Pharmaceutical Preparations	2	2	P.m	53,590	8.26	6,487		6,232	M
5/6/25 16:40	5/2/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	5	6	S	-594	12.89	-46		881	D
5/6/25 16:10	5/2/25	RNXT	Renovorx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	10	M.dm	122	0.7484	164	12	1,512	D
5/6/25 16:05	5/2/25	NUVB	Nuvation Bio Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	M.dm	1,076	1.68	640	1	58,993	D
5/6/25 16:05	5/2/25	NUVB	Nuvation Bio Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	S.dm	-1,076	1.68	-640		58,993	D
5/5/25 21:54	5/2/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	5	11	M.d	645	9.31	69	9	830	D
5/5/25 21:54	5/5/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	5	11	S.d	-645	9.31	-69		830	D
5/5/25 20:40	12/16/24	BOLT	Bolt Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P.dm	6	0.5670	10	23	53	D
5/5/25 19:18	4/21/25	RARE	Ultragenyx Pharmaceutical Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	10	S.dm	-6,838	42.13	-162		3,565	D
5/5/25 17:34	5/2/25	DERM	Journey Medical Corp	DE	Health	Drug	Pharmaceutical Preparations	3	7	S.m	-887	5.17	-172		3,057	D
5/5/25 17:10	5/1/25	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	2	3	M.d	1,874	47.74	39	319	52	D
5/5/25 16:23	5/3/25	MRK	Merck & Co., Inc.	NJ	Health	Drug	Pharmaceutical Preparations	3	6	M.dm	2,209	79.38	28	257	39	D
5/5/25 16:20	5/1/25	ACRS	Aclaris Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	5	M.d	0	0.00	93	5	1,838	D
5/5/25 16:08	5/1/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	S.dm	-528	3.36	-157		281	D
5/2/25 20:41	4/30/25	HRTX	Heron Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	3	7	M.d	0	0.00	142	26	685	D
5/2/25 20:27	5/1/25	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	3	6	S.d	-7,641	14.82	-515		10,831	D
5/2/25 20:00	5/1/25	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	7	M.dm	25,699	30.45	844	8	11,272	D
5/2/25 20:00	5/1/25	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	7	S.dm	-25,699	30.45	-844		11,272	D
5/2/25 19:55	5/1/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	13	M.d	3,816	26.52	144	25	715	D
5/2/25 19:55	5/1/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	13	S.d	-3,816	26.52	-144		715	D
5/2/25 18:18	5/2/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	8	S.d	-255	5.54	-46		139	D
5/2/25 17:04	4/30/25	ABT	Abbott Laboratories	IL	Health	Drug	Pharmaceutical Preparations	7	8	S.dm	-20,513	108.35	-189		408	D
5/2/25 16:38	5/1/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	6	9	P.d	738	15.09	49	14	392	D
5/1/25 19:23	4/30/25	BTAI	Bioxcel Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	7	M.dm	0	0.00	6	1	500	D
5/1/25 19:07	4/30/25	ACRV	Acrivon Therapeutics, Inc.		Health	Drug	Pharmaceutical Preparations	1	2	S.m	-3,763	1.67	-2,257		3,841	I
5/1/25 16:53	4/29/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	11	M.dm	9,105	35.94	253		66	D
5/1/25 16:53	4/29/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	11	S.dm	-9,105	35.94	-253		66	D
4/30/25 17:07	4/30/25	ZNTL	Zentalis Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	1	1	P	29	1.40	21	8	281	D
4/30/25 16:45	4/28/25	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	5	8	M.d	4,693	31.01	151	25	768	D
4/30/25 16:15	4/28/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	6	17	S.d	-591	10.72	-55		4,258	D
4/29/25 06:14	4/25/25	GLSI	Greenwich Lifesciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	4	P	165	9.11	18	0	5,571	D
4/28/25 07:07	2/7/25	ZBIO	Zenas Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P.a	78	7.76	10		10	D
4/23/25 18:00	4/21/25	TBPH	Theravance Biopharma, Inc.	E9	Health	Drug	Pharmaceutical Preparations	1	1	S	-36	9.00	-4		370	D
4/22/25 21:00	4/18/25	AMRN	Amarin Corp Plcuk	X0	Health	Drug	Pharmaceutical Preparations	9	9	M.dm	0	0.00	12	17	83	D
4/22/25 17:38	4/30/24	VREO	Vireo Growth Inc.	A1	Health	Drug	Pharmaceutical Preparations	2	8	P.dm	20,262	0.6182	32,776	16	237,654	D
4/22/25 07:01	4/17/25	PEPG	Pepgen Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	P	66	1.22	54	87	117	D
4/21/25 17:00	4/18/25	SIGA	Siga Technologies Inc	DE	Health	Drug	Pharmaceutical Preparations	1	2	M.d	0	0.00	14	56	38	D
4/21/25 16:05	4/17/25	MRUS	Merus N.V.	P7	Health	Drug	Pharmaceutical Preparations	2	4	M.d	600	14.18	42	999%	42	D
4/21/25 16:04	4/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	5	S	-29	1.49	-19		2,424	D
4/17/25 16:05	4/15/25	GBIO	Generation Bio Co.	DE	Health	Drug	Pharmaceutical Preparations	5	5	M.d	0	0.00	12	1	2,039	D
4/17/25 16:05	4/15/25	ETNB	89Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-91	5.95	-15		343	D
4/15/25 17:30	3/31/25	ASMB	Assembly Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	S.d	-15	9.85	-1		49	D
4/15/25 16:31	4/14/25	SDGR	Schrodinger, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	M.d	606	15.30	40	128	71	D
4/15/25 16:31	4/14/25	SDGR	Schrodinger, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	S.d	-606	15.30	-40		71	D
4/15/25 16:30	4/13/25	CELU	Celularity Inc	DE	Health	Drug	Pharmaceutical Preparations	4	4	M.d	0	0.00	7	10	77	D
4/15/25 14:02	4/10/25	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	P.m	106	1.08	98	3	3,758	D
4/15/25 12:50	4/2/25	NBY	Novabay Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	7	P.m	314	0.6251	502	97	1,020	D
4/15/25 07:59	4/14/25	TXMD	Therapeuticsmd, Inc.	NV	Health	Drug	Pharmaceutical Preparations	2	3	P.m	3	0.9009	3	3	103	D
4/14/25 19:26	4/11/25	VKTX	Viking Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	M.d	226	9.72	23	21	133	D
4/14/25 17:17	4/11/25	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	7	15	M.dm	198	1.49	133	22	737	D
4/11/25 21:57	4/4/25	KROS	Keros Therapeutics, Inc.		Health	Drug	Pharmaceutical Preparations	2	2	M.d	9,479	9.64	984	21	5,693	D
4/11/25 18:20	4/9/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	4	S.dm	-9,908	12.50	-793		4,062	D
4/11/25 17:22	4/1/25	PCSA	Processa Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	M	0	0.00	61	16	435	D
4/11/25 13:23	4/10/25	GOVX	Geovax Labs, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	P	34	1.03	33	92	68	D
4/10/25 19:06	4/9/25	PVLA	Palvella Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	1	P	101	20.20	5	3	197	M
4/10/25 17:07	4/10/25	OPK	Opko Health, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	6	P.d	1,237	1.61	767	0	247,698	I
4/10/25 16:15	4/8/25	ACUT	Accustem Sciences Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	P.m	104	0.5428	191	4	4,911	I
4/10/25 16:02	4/8/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	14	M.d	1,138	9.30	122	48	379	D
4/10/25 16:02	4/10/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	14	S.d	-1,138	9.30	-122		379	D
4/10/25 08:39	4/8/25	MBX	Mbx Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	45	5.89	8	46	24	D
4/8/25 16:41	4/7/25	DMAC	Diamedica Therapeutics Inc.	Z4	Health	Drug	Pharmaceutical Preparations	1	1	M.d	51	2.11	24	8	313	D
4/7/25 18:43	4/3/25	ALDX	Aldeyra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-4,828	1.42	-3,400		5,876	I
4/7/25 17:18	4/3/25	IBO	Impact Biomedical Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	1	S	-174	0.4950	-352	-100	0	I
4/7/25 16:11	4/4/25	PRLD	Prelude Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	3	6	M.dm	651	0.6911	941	29	4,224	D
4/4/25 19:27	4/2/25	MNPR	Monopar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	3	4	S.d	-1,167	25.79	-45		1,786	D
4/4/25 17:35	4/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	6	6	S.m	-85	7.73	-11		838	D
4/4/25 16:34	4/3/25	TRDA	Entrada Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	M.d	42	3.28	13	12	121	D
4/4/25 16:30	4/2/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	5	M.d	1,277	11.19	114	8	1,571	D
4/4/25 16:18	4/4/25	BFRG	Bullfrog Ai Holdings, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	2	S.m	-74	1.48	-50		2,348	D
4/4/25 16:13	4/2/25	SEPN	Septerna, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	7	M.dm	7,194	5.80	1,241	12	11,412	D
4/4/25 07:30	4/3/25	APRE	Aprea Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	10	1.84	6	2	347	D
4/3/25 19:27	4/2/25	CKPT	Checkpoint Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-111	4.04	-27		5,206	D
4/3/25 17:00	4/1/25	VERV	Verve Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	12	M.d	100	0.9713	103	10	1,099	D
4/3/25 17:00	4/2/25	VERV	Verve Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	12	S.d	-100	0.9713	-103		1,099	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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