Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	#o	#f	T	TVal	Price	Qty	oc	Own	H
9/3/25 06:04	8/28/25	SPRO	Spero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-16	1.97	-8		1,443	D
9/2/25 21:52	8/25/25	STTK	Shattuck Labs, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P.d	10,944	0.8677	12,612		2,102	I
9/2/25 20:30	9/2/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	10	22	S.d	-27,650	31.58	-876		1,627	D
9/2/25 19:46	8/28/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	10	26	S.dm	-22,672	25.06	-905		10,628	I
9/2/25 19:11	9/2/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	9	S.dm	-21,060	90.70	-232		137	D
9/2/25 19:00	8/31/25	BTAI	Bioxcel Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	9	M.dm	0	0.00	7	1	517	D
9/2/25 16:41	9/2/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	4	18	S.d	-2,052	34.83	-59		592	D
9/2/25 16:39	8/21/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	10	27	M.dm	37,432	210.49	178		103	D
9/2/25 16:39	8/21/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	10	27	S.dm	-37,432	210.49	-178		103	D
9/2/25 16:10	8/29/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	7	10	S.dm	-32,029	308.67	-104		206	D
9/2/25 13:05	8/28/25	CALC	Calcimedica, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	22	P.dm	236	2.33	101	4	2,465	I
8/29/25 20:35	8/27/25	CVKD	Cadrenal Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S.m	-98	13.99	-7		445	D
8/29/25 18:46	8/22/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	5	21	S.dm	-6,971	5.45	-1,279		1,479	D
8/29/25 17:30	8/27/25	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	3	5	S.dm	-4,974	46.55	-107		624	D
8/29/25 17:21	8/28/25	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	4	5	M.d	1,853	7.01	264	10	2,914	D
8/29/25 17:21	8/28/25	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	4	5	S.d	-1,853	7.01	-264		2,914	D
8/29/25 17:03	8/27/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	20	M.dm	2,318	18.93	123	6	2,244	D
8/29/25 17:03	8/27/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	20	S.dm	-2,318	18.93	-123		2,244	D
8/29/25 16:55	8/21/25	AKTX	Akari Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	1	4	P.m	57	1.09	52	21	299	D
8/29/25 16:21	8/19/25	PGEN	Precigen, Inc.	VA	Health	Drug	Pharmaceutical Preparations	1	2	P.dm	99	0.6457	153	305	203	D
8/29/25 16:19	8/27/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	8	S.dm	-10,218	21.55	-474		2,096	I
8/29/25 16:09	8/27/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	13	32	M.d	2,361	12.43	190	61	502	D
8/29/25 16:09	8/27/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	13	32	S.d	-2,361	12.43	-190		502	D
8/29/25 16:05	8/25/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	17	M.dm	14,098	28.29	498	28	2,309	D
8/29/25 16:05	8/25/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	17	S.dm	-14,098	28.29	-498		2,309	D
8/29/25 16:05	8/28/25	AARD	Aardvark Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	73	4.24	17	1	2,987	D
8/29/25 16:02	8/27/25	VRTX	Vertex Pharmaceuticals Inc / Ma	MA	Health	Drug	Pharmaceutical Preparations	3	3	S	-5,947	389.56	-15		166	D
8/28/25 20:39	8/26/25	BYSI	Beyondspring Inc.		Health	Drug	Pharmaceutical Preparations	1	5	S.m	-1,340	2.89	-464		4,488	I
8/28/25 19:32	8/26/25	QTTB	Q32 Bio Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-32	1.80	-18		265	D
8/28/25 19:30	8/26/25	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	10	M.d	2,510	4.08	616	11	6,114	D
8/28/25 19:30	8/26/25	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	10	S.d	-2,510	4.08	-616		6,114	D
8/28/25 17:40	8/26/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	7	M.dm	4,175	17.74	235	3	7,364	D
8/28/25 17:40	8/26/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	7	S.dm	-4,175	17.74	-235		7,364	D
8/28/25 17:00	8/27/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	8	M.dm	9,380	13.54	693	13	5,989	D
8/28/25 17:00	8/27/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	8	S.dm	-9,380	13.54	-693		5,989	D
8/28/25 16:56	8/26/25	RLMD	Relmada Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	1	P.m	178	0.6696	266	36	1,000	D
8/28/25 16:55	8/26/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	14	M.d	1,729	6.51	266	97	538	D
8/28/25 16:55	8/26/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	14	S.d	-1,729	6.51	-266		538	D
8/28/25 16:25	8/27/25	AMRX	Amneal Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	6	11	S.dm	-12,059	8.40	-1,435		2,658	D
8/28/25 16:14	7/24/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	12	12	S.d	-231,475	797.67	-290	0	96,846	D
8/28/25 16:05	8/27/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	2	2	S	-20	15.62	-1		181	D
8/27/25 20:54	8/27/25	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	8	P.m	145	3.10	47	9	586	D
8/27/25 18:44	8/25/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	4	4	S	-355	12.04	-29		4,221	D
8/27/25 17:16	8/18/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	1	20	M.dm	624	3.13	199		0	D
8/27/25 17:16	8/18/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	1	20	S.dm	-624	3.13	-199	-100	0	D
8/27/25 17:08	8/11/25	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	4	9	P.dm	9,046	17.45	518	8	6,956	I
8/27/25 16:30	8/7/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	24	M.dm	15,960	51.13	312	284	422	D
8/27/25 16:30	8/7/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	24	S.dm	-15,960	51.13	-312		422	D
8/26/25 21:54	8/25/25	DERM	Journey Medical Corp	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	81	0.0650	1,250	110	2,387	D
8/26/25 21:40	8/22/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	5	8	S.d	-3,027	9.61	-315		6,193	D
8/26/25 20:00	8/22/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	24	M.d	1,545	8.02	193	40	674	D
8/26/25 20:00	8/25/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	24	S.d	-1,545	8.02	-193		674	D
8/26/25 18:56	8/22/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	6	33	M.dm	13,165	46.30	284	10	3,071	D
8/26/25 18:56	8/22/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	6	33	S.dm	-13,165	46.30	-284		3,071	D
8/26/25 18:26	8/22/25	EOLS	Evolus, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	S.m	-1,720	9.36	-184		594	D
8/26/25 18:19	8/22/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	13	18	S.dm	-38,015	83.45	-456		1,905	D
8/26/25 18:01	8/22/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	15	S.dm	-8,717	41.91	-208		1,467	I
8/26/25 17:23	8/22/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	12	17	S.d	-2,111	24.94	-85		963	D
8/26/25 17:17	7/10/25	ELTP	Elite Pharmaceuticals Inc /Nv/	NJ	Health	Drug	Pharmaceutical Preparations	3	5	P.d	538	0.0940	5,716	520	6,816	D
8/26/25 16:30	8/22/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	5	M.d	5,042	20.00	252		166	D
8/26/25 16:30	8/22/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	5	S.d	-5,042	20.00	-252		166	D
8/26/25 16:15	8/22/25	TNGX	Tango Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S	-9,828	7.01	-1,402		15,759	D
8/26/25 15:41	8/22/25	DRRX	Durect Corp	DE	Health	Drug	Pharmaceutical Preparations	1	2	P.m	398	1.89	210	6	3,643	D
8/26/25 06:10	8/22/25	RNXT	Renovorx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P.m	39	1.25	31	3	1,065	D
8/25/25 20:59	8/21/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	12	32	M.dm	11,101	40.21	276		206	D
8/25/25 20:59	8/21/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	12	32	S.dm	-11,101	40.21	-276		206	D
8/25/25 19:12	8/22/25	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	3	5	M.d	43,185	141.86	304	153	503	D
8/25/25 19:12	8/22/25	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	3	5	S.d	-43,185	141.86	-304		503	D
8/25/25 08:50	8/22/25	DVAX	Dynavax Technologies Corp	DE	Health	Drug	Pharmaceutical Preparations	2	2	P.m	22,393	10.82	2,069	15	15,761	D
8/22/25 21:00	6/18/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	2	8	S.dm	-26,164	10.51	-2,491		53,438	D
8/22/25 19:07	8/21/25	SKYE	Skye Bioscience, Inc.	NV	Health	Drug	Pharmaceutical Preparations	2	2	S.m	-1,601	3.46	-463		19,364	I
8/22/25 16:58	8/21/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	17	S.dm	-185,331	43.47	-4,263		26,998	D
8/22/25 16:30	8/21/25	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	9	S.dm	-15,837	17.12	-925		32,459	I
8/22/25 16:19	8/21/25	BHC	Bausch Health Companies Inc.	NJ	Health	Drug	Pharmaceutical Preparations	2	5	S.m	-369,750	8.34	-44,333		70,830	D
8/22/25 16:07	8/21/25	LYEL	Lyell Immunopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	S.m	-134	10.53	-13		124	D
8/22/25 13:27	8/22/25	PRGO	Perrigo Co Plc	L2	Health	Drug	Pharmaceutical Preparations	5	8	P.d	1,580	25.73	61	33	247	D
8/21/25 21:32	8/19/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	14	S.dm	-1,319	10.11	-130		10,485	D
8/21/25 21:05	8/19/25	NKTR	Nektar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	3	3	S.d	-79	26.59	-3		109	D
8/21/25 20:44	8/21/25	CLNN	Clene Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-18	5.34	-3	0	705	D
8/21/25 17:44	8/18/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	20	S.dm	-174,220	229.16	-760		4,029	D
8/21/25 17:22	8/21/25	TNXP	Tonix Pharmaceuticals Holding Corp.	NV	Health	Drug	Pharmaceutical Preparations	2	2	P	24	36.02	1		1	D
8/21/25 17:07	8/4/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	7	31	M.dm	74,168	63.63	1,166	504	1,397	D
8/21/25 17:07	8/4/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	7	31	S.dm	-74,168	63.63	-1,166		1,397	D
8/21/25 16:19	8/13/25	MGNX	Macrogenics Inc	DE	Health	Drug	Pharmaceutical Preparations	2	2	M.dm	151	0.9849	153	19	941	D
8/20/25 17:14	6/10/25	ETON	Eton Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	P.m	1,304	15.58	84	2	3,672	I
8/20/25 16:57	8/18/25	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	4	10	M.d	3,418	28.21	121	4	3,445	D
8/20/25 16:57	8/18/25	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	4	10	S.d	-3,418	28.21	-121		3,445	D
8/20/25 16:38	8/19/25	ZVRA	Zevra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	P.d	267	2.79	96	598	112	D
8/20/25 16:36	8/18/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	8	22	M.dm	25,072	21.58	1,162		318	D
8/20/25 16:36	8/18/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	8	22	S.dm	-25,072	21.58	-1,162		318	D
8/20/25 16:13	8/18/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	11	S.d	-31,219	10.13	-3,083		4,145	D
8/20/25 16:04	8/19/25	GOSS	Gossamer Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	50	1.92	26	81	58	D
8/20/25 16:02	8/18/25	ALXO	Alx Oncology Holdings Inc	DE	Health	Drug	Pharmaceutical Preparations	3	5	P	62	0.7590	82	28	377	D
8/20/25 16:01	8/15/25	ARCT	Arcturus Therapeutics Holdings Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	P	41	16.56	2	1	222	D
8/19/25 21:32	8/15/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	33	M.dm	13,858	42.25	328	37	1,204	D
8/19/25 19:40	8/15/25	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	M.d	191	1.92	99	5	2,145	D
8/19/25 19:40	8/18/25	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	S.d	-191	1.92	-99		2,145	D
8/19/25 18:00	8/18/25	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-554	25.18	-22		40	D
8/19/25 17:02	8/18/25	SEPN	Septerna, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	94	4.10	23	22	128	D
8/19/25 16:40	8/15/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	6	23	M.dm	9,701	15.97	607	415	754	D
8/19/25 16:40	8/18/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	6	23	S.dm	-9,701	15.97	-607		754	D
8/19/25 16:15	8/15/25	HRMY	Harmony Biosciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-787	36.50	-22	-100	0	D
8/19/25 16:08	8/15/25	MCRB	Seres Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	M.d	7	3.80	2	7	28	D
8/19/25 16:08	8/18/25	MCRB	Seres Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	S.d	-7	3.80	-2		28	D
8/19/25 16:01	8/18/25	COYA	Coya Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	19	1.09	18	176	28	D
8/18/25 18:00	8/14/25	ATAI	Atai Life Sciences N.V.	P7	Health	Drug	Pharmaceutical Preparations	1	1	P	19,000	2.19	8,676	20	52,845	I
8/18/25 17:14	8/15/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	3	S	-340	13.33	-26		444	D
8/18/25 17:02	8/14/25	SNDX	Syndax Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	3	4	M.dm	1,372	11.06	124	27	583	D
8/18/25 17:02	8/14/25	SNDX	Syndax Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	3	4	S.dm	-1,372	11.06	-124		583	D
8/18/25 16:33	8/15/25	EBS	Emergent Biosolutions Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-131	8.75	-15		209	D
8/15/25 18:13	8/15/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	4	17	M.d	3,261	9.42	346	96	709	D
8/15/25 18:13	8/15/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	4	17	S.d	-3,261	9.42	-346		709	D
8/15/25 17:59	8/13/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.m	-200	20.00	-10		262	D
8/15/25 16:40	8/1/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	7	24	S.dm	-73,790	214.81	-344		68,028	D
8/15/25 16:30	8/14/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	13	S	-1,590	6.25	-255		2,698	D
8/15/25 16:09	8/13/25	ALDX	Aldeyra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P	127	5.17	25	12	224	D
8/15/25 12:45	8/13/25	NATR	Natures Sunshine Products Inc	UT	Health	Drug	Pharmaceutical Preparations	3	3	S	-32,962	11.49	-2,870		162	D
8/14/25 18:02	8/12/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	9	M.dm	1,963	12.79	153	15	1,155	D
8/14/25 18:02	8/13/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	9	S.dm	-1,963	12.79	-153		1,155	D
8/14/25 17:00	8/12/25	ABBV	Abbvie Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	M.d	13,371	136.39	98	68	242	D
8/14/25 17:00	8/12/25	ABBV	Abbvie Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S.d	-13,371	136.39	-98		242	D
8/14/25 16:20	8/12/25	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.m	-246	8.21	-30		157	D
8/14/25 16:15	8/13/25	DSGN	Design Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-2,954	5.25	-563		3,655	I
8/14/25 16:05	8/12/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P.m	303	6.06	50	9	630	D
8/14/25 16:01	8/13/25	MDCX	Medicus Pharma Ltd.	A6	Health	Drug	Pharmaceutical Preparations	1	1	M.d	156	1.08	145	38	528	D
8/13/25 18:08	8/12/25	VTRS	Viatris Inc	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	220	9.99	22	8	315	D
8/13/25 18:00	8/11/25	LGVN	Longeveron Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P.d	0	0.00	24	8	303	D
8/13/25 16:08	8/11/25	ORGO	Organogenesis Holdings Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	M.dm	735	2.87	256	20	1,519	D
8/13/25 16:05	8/7/25	BIVI	Biovie Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	1	P.d	0	0.00	5	100	10	I
8/13/25 16:05	8/11/25	IRWD	Ironwood Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	4	4	S	-11	0.8400	-13		1,101	D
8/13/25 13:58	8/11/25	ZOMDF	Zomedica Corp.	A0	Health	Drug	Pharmaceutical Preparations	1	3	P.m	82	0.0398	2,056	64	5,256	D
8/13/25 09:58	8/11/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	2	7	S.d	-457	7.11	-64		200	D
8/13/25 08:28	8/11/25	BBOT	Bridgebio Oncology Therapeutics, Inc.	E9	Health	Drug	Pharmaceutical Preparations	4	4	M.d	0	0.00	4,262	31	17,969	I
8/12/25 20:00	8/11/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	11	S.dm	-5,852	29.82	-196		383	D
8/12/25 20:00	8/12/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	11	M.dm	5,852	29.82	196	105	383	D
8/12/25 18:00	7/31/25	HRTX	Heron Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	5	10	M.d	6,231	1.46	4,258	12	38,713	D
8/12/25 16:05	8/11/25	OGN	Organon & Co.		Health	Drug	Pharmaceutical Preparations	1	1	M.d	0	0.00	12	87	25	D
8/12/25 16:02	8/8/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	7	13	M.d	1,054	9.43	112	922	124	D
8/12/25 16:02	8/8/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	7	13	S.d	-1,054	9.43	-112		124	D
8/12/25 07:00	8/8/25	ITRM	Iterum Therapeutics Plc	L2	Health	Drug	Pharmaceutical Preparations	1	1	P	11	0.7236	15	7	235	D
8/11/25 17:53	8/8/25	ABT	Abbott Laboratories	IL	Health	Drug	Pharmaceutical Preparations	1	1	S	-747	134.55	-6		51	D
8/11/25 16:35	8/11/25	RPRX	Royalty Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	1	1	S.d	-1,214	36.23	-34		195	D
8/11/25 16:09	8/7/25	PCRX	Pacira Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-116	23.67	-5		11	D
8/11/25 09:12	7/1/25	CPIX	Cumberland Pharmaceuticals Inc		Health	Drug	Pharmaceutical Preparations	4	12	P.m	22	4.22	5	0	6,065	D
8/8/25 16:56	8/8/25	OPK	Opko Health, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	891	1.32	675	0	248,373	I
8/8/25 16:05	8/7/25	VNDA	Vanda Pharmaceuticals Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P	74	4.33	17	1	2,433	D
8/8/25 15:13	8/7/25	GOVX	Geovax Labs, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	1	0.6703	1	46	3	D
8/7/25 16:15	8/5/25	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	4	7	S.m	-149	0.9948	-150		8,360	D
8/6/25 20:38	8/6/25	VSTM	Verastem, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	6	S.m	-127	5.19	-24		716	D
8/5/25 20:32	8/1/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	14	36	M.d	17,470	5.72	3,055	11	31,356	D
8/5/25 20:32	8/1/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	14	36	S.d	-17,470	5.72	-3,055		31,356	D
8/5/25 18:01	8/1/25	BMY	Bristol Myers Squibb Co	DE	Health	Drug	Pharmaceutical Preparations	2	3	M.d	17	7.68	2	19	14	D
8/5/25 17:31	8/1/25	AUPH	Aurinia Pharmaceuticals Inc.		Health	Drug	Pharmaceutical Preparations	2	2	S.m	-13,800	10.45	-1,320		11,463	D
8/5/25 17:03	8/1/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	2	4	S	-293	121.89	-2		79	D
8/5/25 16:54	8/1/25	JAZZ	Jazz Pharmaceuticals Plc	L2	Health	Drug	Pharmaceutical Preparations	1	2	S	-221	110.42	-2	0	437	D
8/5/25 16:04	8/1/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	13	15	M.d	1,844	6.49	284	7	4,328	D
8/5/25 16:04	8/1/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	13	15	S.d	-1,844	6.49	-284		4,328	D
8/5/25 08:46	8/4/25	MRK	Merck & Co., Inc.	NJ	Health	Drug	Pharmaceutical Preparations	2	2	M.d	4,283	79.29	54	79	122	D
8/4/25 19:23	7/30/25	CYCC	Cyclacel Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-83	12.36	-7		156	D
8/4/25 19:17	8/1/25	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	2	3	S.d	-2,628	13.08	-201		10,938	D
8/4/25 18:28	7/31/25	LRMR	Larimar Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	30,000	3.20	9,375	44	30,607	I
8/4/25 17:00	8/1/25	AMRN	Amarin Corp Plcuk	X0	Health	Drug	Pharmaceutical Preparations	2	2	M.d	0	0.00	75	802	85	D
8/4/25 16:43	8/3/25	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	3	3	M.dm	210	17.54	12	4	315	D
8/4/25 09:00	7/31/25	ANIX	Anixa Biosciences Inc	DE	Health	Drug	Pharmaceutical Preparations	3	5	P	111	3.16	35	2	1,658	D
8/1/25 17:09	8/1/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	7	S.d	-209	4.05	-52		154	D
8/1/25 16:30	7/30/25	ANNX	Annexon, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	5	P	28	2.48	11	3	391	D
8/1/25 16:30	7/30/25	ALZN	Alzamend Neuro, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	3	S.dm	-628	2.58	-243		96	I
7/30/25 17:12	7/29/25	LEXX	Lexaria Bioscience Corp.	NV	Health	Drug	Pharmaceutical Preparations	5	5	P.dm	49	0.9153	54	5	1,116	I
7/30/25 16:56	7/29/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-2	4.17	0		37	D
7/28/25 17:14	7/25/25	ZTS	Zoetis Inc.		Health	Drug	Pharmaceutical Preparations	1	1	M.d	0	0.00	1	100	3	D
7/25/25 19:06	7/23/25	IGMS	Igm Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	7	S	-41	1.26	-32		616	D
7/25/25 18:54	7/23/25	DMAC	Diamedica Therapeutics Inc.	Z4	Health	Drug	Pharmaceutical Preparations	3	3	P	16,800	3.50	4,800	31	20,107	I
7/23/25 21:10	7/21/25	HROW	Harrow, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	M.dm	5,646	8.96	630	10	6,791	D
7/23/25 18:09	7/22/25	HOOK	Hookipa Pharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-39	0.9200	-43		136	D
7/23/25 17:00	7/22/25	MURA	Mural Oncology Plc	L2	Health	Drug	Pharmaceutical Preparations	2	3	S	-42	2.45	-17		364	D
7/23/25 16:16	7/21/25	SGMT	Sagimet Biosciences Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-772	9.13	-85		980	D
7/22/25 19:51	7/18/25	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	9	10	S.m	-630	3.44	-183		7,914	D
7/22/25 15:24	7/22/25	ETST	Earth Science Tech, Inc.	FL	Health	Drug	Pharmaceutical Preparations	2	4	P.m	48	0.1983	244	0	124,630	D
7/22/25 07:36	6/6/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	3	3	M.d	717	2.18	329	35	1,262	D
7/21/25 16:43	7/17/25	APVO	Aptevo Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	9	9	M.d	0	0.00	0	650	0	D
7/18/25 16:07	7/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	5	S	-51	1.12	-45		2,417	D
7/18/25 16:05	7/17/25	MRUS	Merus N.V.	P7	Health	Drug	Pharmaceutical Preparations	1	6	M.dm	6,267	37.98	165		0	D
7/18/25 16:05	7/17/25	MRUS	Merus N.V.	P7	Health	Drug	Pharmaceutical Preparations	1	6	S.dm	-6,267	37.98	-165	-100	0	D
7/18/25 16:05	7/16/25	PHAT	Phathom Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-14	8.36	-2		54	D
7/17/25 20:51	7/16/25	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	2	3	S	-583	3.97	-147		1,767	D
7/17/25 18:20	7/15/25	ETNB	89Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-115	11.02	-10		324	D
7/17/25 16:10	7/15/25	GBIO	Generation Bio Co.	DE	Health	Drug	Pharmaceutical Preparations	5	5	M.d	0	0.00	12	1	2,082	D
7/16/25 21:06	7/14/25	MNPR	Monopar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	4	5	S.d	-1,700	27.11	-63		968	D
7/16/25 18:01	7/14/25	TBPH	Theravance Biopharma, Inc.	E9	Health	Drug	Pharmaceutical Preparations	1	1	S	-114	11.39	-10		327	D
7/15/25 17:11	7/14/25	DYN	Dyne Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	P	985	9.33	106	30	463	D
7/15/25 07:00	7/11/25	AVBP	Arrivent Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	25	2.28	11	2	530	D
7/14/25 16:30	7/10/25	COGT	Cogent Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	25,000	9.00	2,778	45	9,003	I
7/11/25 17:27	5/13/24	TRDA	Entrada Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	5	P.m	2,870	8.11	354	4	8,684	D
7/10/25 17:15	7/10/25	OTLC	Oncotelic Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P.m	1	0.0050	199	0	117,041	D
7/10/25 16:45	7/8/25	LFCR	Lifecore Biomedical, Inc. De	DE	Health	Drug	Pharmaceutical Preparations	3	3	M.d	0	0.00	262	27	1,234	D
7/8/25 17:55	7/7/25	BRFG	Bullfrog Ai Holdings, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	2	S.m	-77	1.53	-50		2,321	D
7/8/25 16:20	7/3/25	BPMC	Blueprint Medicines Corp	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-285	128.25	-2		117	D
7/8/25 16:06	7/4/25	PRLD	Prelude Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	0	0.00	9	13	81	D
7/8/25 16:00	7/3/25	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	M.d	4	1.09	4	137	6	D
7/8/25 16:00	7/3/25	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	S.d	-4	1.09	-4		6	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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