Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	#o	#f	T	TVal	Price	Qty	oc	Own	H
1/21/26 21:00	12/19/25	OLMA	Olema Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	12	M.dm	26,882	19.82	1,356	183	2,099	D
1/21/26 21:00	12/19/25	OLMA	Olema Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	12	S.dm	-26,882	19.82	-1,356		2,099	D
1/21/26 19:17	11/24/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	1	36	M.dm	285	1.75	163		6	D
1/21/26 19:17	11/24/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	1	36	S.dm	-285	1.75	-163		6	D
1/21/26 18:55	12/17/25	IRON	Disc Medicine, Inc.		Health	Drug	Pharmaceutical Preparations	6	15	S.dm	-85,553	76.42	-1,119		3,170	I
1/21/26 18:13	1/16/26	CLNN	Clene Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	10	S.dm	-3,040	6.20	-491		1,274	I
1/21/26 17:17	1/20/26	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	4	5	S.d	-4,624	66.48	-70		817	D
1/21/26 17:17	1/20/26	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	S	-233	3.65	-64		2,324	D
1/21/26 16:30	1/21/26	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S	-274	5.13	-54		1,227	D
1/21/26 16:20	1/13/26	BIOA	Bioage Labs, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	10	S.d	-6,447	13.45	-479		1,003	D
1/21/26 16:19	1/20/26	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	19	S.d	-1,328	21.46	-62		3,438	D
1/21/26 16:05	12/1/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	8	20	M.dm	17,186	26.84	640	168	1,020	D
1/21/26 16:05	12/1/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	8	20	S.dm	-17,186	26.84	-640		1,020	D
1/21/26 16:05	1/16/26	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	15	M.d	13,465	37.77	357	118	658	D
1/21/26 16:05	1/20/26	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	15	S.d	-13,465	37.77	-357		658	D
1/21/26 16:04	12/15/25	SPRB	Spruce Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	5	M.dm	0	0.00	13	131	24	D
1/21/26 12:46	1/21/26	XCUR	Exicure, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	S	-11,579	5.34	-2,168		5,925	D
1/21/26 09:09	1/16/26	IMRX	Immuneering Corp	DE	Health	Drug	Pharmaceutical Preparations	5	5	P	234	4.52	52	3	1,649	D
1/20/26 21:46	1/15/26	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	9	M.dm	7,187	10.13	710	11	7,301	D
1/20/26 21:46	1/15/26	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	9	S.dm	-7,187	10.13	-710		7,301	D
1/20/26 20:39	1/15/26	HRMY	Harmony Biosciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	6	S.d	-3,449	31.26	-110	-100	0	D
1/20/26 20:33	11/20/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	19	S.dm	-76,399	35.77	-2,136		8,640	I
1/20/26 20:21	1/15/26	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	16	43	M.dm	49,948	50.36	992		902	D
1/20/26 19:57	11/3/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	13	S.d	-1,080	7.65	-141		172	D
1/20/26 19:19	12/15/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	9	M.d	677	3.09	219	26	1,057	D
1/20/26 19:19	12/16/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	9	S.d	-677	3.09	-219		1,057	D
1/20/26 17:58	1/20/26	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	23	S.d	-71,419	246.63	-290		2,157	D
1/20/26 17:39	1/15/26	NKTX	Nkarta, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-66	2.07	-32		558	D
1/20/26 17:00	1/16/26	RPRX	Royalty Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	3	16	S.m	-35,325	38.97	-906		2,057	I
1/20/26 16:52	11/24/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	16	M.dm	2,663	9.68	275	57	754	D
1/20/26 16:52	11/24/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	16	S.dm	-2,663	9.68	-275		754	D
1/20/26 16:33	1/15/26	DVAX	Dynavax Technologies Corp	DE	Health	Drug	Pharmaceutical Preparations	5	8	M.dm	3,609	7.18	503	653	580	D
1/20/26 16:33	1/15/26	DVAX	Dynavax Technologies Corp	DE	Health	Drug	Pharmaceutical Preparations	5	8	S.dm	-3,609	7.18	-503		580	D
1/20/26 16:30	1/16/26	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	10	109	S.edm	-393,658	306.03	-1,286		730	D
1/20/26 16:30	1/16/26	ONCY	Oncolytics Biotech Inc		Health	Drug	Pharmaceutical Preparations	1	1	P	104	1.04	100	27	467	D
1/20/26 16:30	1/12/26	TYRA	Tyra Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	6	S.m	-9,798	18.49	-530		4,130	D
1/20/26 16:07	12/2/25	HOWL	Werewolf Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	36	S.m	-6,525	1.08	-6,019		17,018	I
1/20/26 16:01	1/19/26	IGC	Igc Pharma, Inc.	MD	Health	Drug	Pharmaceutical Preparations	1	1	M.d	0	0.00	100	8	1,371	D
1/20/26 15:00	1/19/26	HRTX	Heron Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	3	6	M.d	0	0.00	80	10	891	D
1/20/26 10:29	10/17/25	MYNZ	Mainz Biomed N.V.	P7	Health	Drug	Pharmaceutical Preparations	1	2	P.e	1,436	1.08	1,329		685	D
1/20/26 09:28	1/16/26	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	15	M.d	3,794	8.36	454	90	957	D
1/16/26 17:26	1/15/26	ORKA	Oruka Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	6	M.d	949	20.64	46	29	207	D
1/16/26 17:26	1/15/26	ORKA	Oruka Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	6	S.d	-949	20.64	-46		207	D
1/16/26 17:22	1/2/26	TERN	Terns Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	7	S.dm	-6,398	14.86	-431		348	D
1/16/26 17:00	1/10/26	ELDN	Eledon Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	6	M.d	0	0.00	26		26	D
1/16/26 16:06	1/15/26	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	9	S.d	-1,738	26.04	-67		1,564	D
1/16/26 16:05	1/15/26	GBIO	Generation Bio Co.		Health	Drug	Pharmaceutical Preparations	3	4	M.d	0	0.00	1	1	192	D
1/16/26 16:02	1/14/26	ACRV	Acrivon Therapeutics, Inc.		Health	Drug	Pharmaceutical Preparations	3	3	P	114	1.69	68	3	2,507	D
1/16/26 13:05	12/23/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	6	37	S.dm	-7,935	22.36	-355		576	D
1/15/26 18:24	1/13/26	PAHC	Phibro Animal Health Corp	DE	Health	Drug	Pharmaceutical Preparations	1	15	S.dm	-7,511	43.07	-174		79	I
1/15/26 16:45	1/13/26	PHAT	Phathom Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	M.d	187	1.73	108	67	269	D
1/15/26 14:35	1/2/26	ACUR	Acura Pharmaceuticals, Inc	NY	Health	Drug	Pharmaceutical Preparations	3	3	M.d	0	0.00	150	4	3,776	D
1/15/26 06:05	1/13/26	GLSI	Greenwich Lifesciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	8	P	489	14.61	34	1	5,604	D
1/14/26 21:00	12/11/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	8	25	M.dm	583,993	17.12	34,117	32	139,172	D
1/14/26 21:00	12/11/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	8	25	S.dm	-583,993	17.12	-34,117		139,172	D
1/14/26 18:20	1/12/26	AKTS	Aktis Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	6	P.d	114,312	18.00	6,351	33	25,418	I
1/14/26 18:14	12/18/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	5	6	S.m	-2,420	87.37	-28		450	D
1/14/26 17:25	1/12/26	OMER	Omeros Corp	WA	Health	Drug	Pharmaceutical Preparations	1	2	S.dm	-843	9.36	-90	-100	0	D
1/14/26 17:25	1/13/26	OMER	Omeros Corp	WA	Health	Drug	Pharmaceutical Preparations	1	2	M.dm	843	9.36	90		0	D
1/14/26 17:12	1/12/26	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	6	15	S.dm	-609	8.82	-69		708	D
1/14/26 16:26	1/12/26	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	2	8	M.d	3,670	20.26	181		61	D
1/14/26 16:26	1/12/26	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	2	8	S.d	-3,670	20.26	-181		61	D
1/14/26 16:23	1/12/26	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	5	10	S.dm	-28,550	299.07	-95		211	D
1/13/26 18:20	1/9/26	ALMS	Alumis Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	16	P.m	50,952	10.55	4,829	10	53,679	I
1/13/26 17:54	11/17/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	10	S.dm	-6,118	22.91	-267		2,310	I
1/13/26 17:11	1/12/26	ZYME	Zymeworks Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	16	M.d	4,674	8.11	576		435	D
1/13/26 17:11	1/12/26	ZYME	Zymeworks Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	16	S.d	-4,674	8.11	-576		435	D
1/13/26 16:36	1/9/26	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	8	32	M.d	11,984	19.33	620	16	4,415	D
1/13/26 16:36	1/12/26	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	8	32	S.d	-11,984	19.33	-620		4,415	D
1/13/26 16:35	1/9/26	ELTP	Elite Pharmaceuticals Inc /Nv/	NJ	Health	Drug	Pharmaceutical Preparations	1	1	M.d	75	0.0300	2,500	71	6,000	D
1/13/26 16:04	1/6/26	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	9	29	S.dm	-76,791	122.84	-625		1,370	D
1/12/26 21:01	1/8/26	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	18	S.dm	-51,560	55.48	-929		7,229	I
1/12/26 16:10	1/8/26	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	1	1	S.m	-2	1.82	-1	0	1,036	D
1/12/26 16:09	1/9/26	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	6	M.d	2,006	27.77	72	52	211	D
1/12/26 08:44	9/19/22	MAIA	Maia Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	14	P.dm	530	1.15	461	12	4,410	I
1/9/26 21:42	1/7/26	ZBIO	Zenas Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P.m	1,639	16.39	100	5	2,075	D
1/9/26 20:30	1/8/26	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	4	10	S.dm	-4,123	5.20	-793		4,787	D
1/9/26 19:34	1/7/26	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	4	6	S.dm	-7,109	22.54	-315		642	D
1/9/26 18:59	1/8/26	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	8	M.d	851	4.68	182	7	2,818	D
1/9/26 18:59	1/8/26	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	8	S.d	-851	4.68	-182		2,818	D
1/9/26 17:37	1/8/26	EQ	Equillium, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	5	S.dm	-292	1.17	-250		127	D
1/9/26 17:34	1/8/26	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	5	10	S.dm	-2,216	4.90	-452		6,685	D
1/9/26 17:15	1/7/26	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	4	11	M.dm	40,565	312.27	130	0	52,514	D
1/9/26 17:15	1/7/26	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	4	11	S.dm	-40,565	312.27	-130	0	52,514	D
1/9/26 17:13	1/7/26	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	9	S.d	-1,815	65.33	-28		719	D
1/9/26 16:53	1/7/26	MIST	Milestone Pharmaceuticals Inc.	A8	Health	Drug	Pharmaceutical Preparations	1	1	S.m	-98	2.25	-44		304	D
1/9/26 16:35	12/15/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	4	17	M.d	9,997	26.28	380		128	D
1/9/26 16:35	12/15/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	4	17	S.d	-9,997	26.28	-380		128	D
1/9/26 16:10	1/1/26	ALT	Altimmune, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	7	M.d	127	2.15	59	124	107	D
1/9/26 16:05	1/7/26	VRTX	Vertex Pharmaceuticals Inc / Ma	MA	Health	Drug	Pharmaceutical Preparations	5	11	S.dm	-90,942	285.03	-319		141	D
1/8/26 21:20	1/7/26	ERAS	Erasca, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	M.d	875	3.65	240		25	D
1/8/26 21:20	1/7/26	ERAS	Erasca, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-875	3.65	-240		25	D
1/8/26 20:35	1/6/26	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	5	20	M.dm	19,013	18.94	1,004	46	3,180	D
1/8/26 20:35	1/6/26	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	5	20	S.dm	-19,013	18.94	-1,004		3,180	D
1/8/26 20:27	1/6/26	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	S.m	-419	5.60	-75		7,549	D
1/8/26 17:23	1/8/26	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	1	8	M.d	1,031	26.10	39	131	70	D
1/8/26 17:23	1/8/26	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	1	8	S.d	-1,031	26.10	-39		70	D
1/8/26 16:57	12/31/25	ZNTL	Zentalis Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	2	2	P	17,727	1.27	13,960	232	19,970	D
1/8/26 16:20	1/6/26	RNAC	Cartesian Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	6	S.d	-514	6.20	-83		628	D
1/8/26 16:05	11/25/25	CVRX	Cvrx, Inc.	NJ	Health	Drug	Pharmaceutical Preparations	1	5	S.m	-861	10.14	-85		4,051	I
1/8/26 16:05	1/6/26	HROW	Harrow, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S.d	-2,015	7.75	-260		7,682	I
1/8/26 16:03	11/7/25	REGN	Regeneron Pharmaceuticals, Inc.	NY	Health	Drug	Pharmaceutical Preparations	8	14	S.dm	-221,763	486.32	-456		1,954	D
1/8/26 16:00	11/13/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	2	24	S.e	-1,027,444	389.58	-2,637		94,237	D
1/7/26 21:34	11/13/25	BHVN	Biohaven Ltd.	D8	Health	Drug	Pharmaceutical Preparations	7	9	P.d	33,145	7.45	4,446	38	16,166	D
1/7/26 20:15	1/5/26	ANTX	An2 Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	6	S.m	-54	1.02	-53		394	D
1/7/26 19:00	1/5/26	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	8	M.dm	66,832	79.39	842	13	7,362	D
1/7/26 19:00	1/5/26	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	8	S.dm	-66,832	79.39	-842		7,362	D
1/7/26 17:46	11/3/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	9	24	S.dm	-8,616	21.57	-399		1,668	D
1/7/26 17:27	11/24/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	27	S.dm	-95,591	82.91	-1,153		19,533	I
1/7/26 17:11	1/5/26	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	M.d	1,467	16.71	88	6	1,528	D
1/7/26 17:11	1/5/26	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	S.d	-1,467	16.71	-88		1,528	D
1/7/26 16:55	1/5/26	CLYM	Climb Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	P.dm	780	2.42	322	3	11,301	I
1/7/26 16:30	1/6/26	ALXO	Alx Oncology Holdings Inc	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-4	1.11	-4		88	D
1/7/26 16:23	10/30/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	20	M.d	1,325	11.38	116	55	329	D
1/7/26 16:23	10/30/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	20	S.d	-1,325	11.38	-116		329	D
1/7/26 16:18	12/31/25	ZVRA	Zevra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	0	0.00	141	999%	144	D
1/7/26 16:15	12/16/25	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	19	S.dm	-10,452	19.74	-530		4,178	D
1/7/26 16:05	1/5/26	IRWD	Ironwood Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-183	4.41	-41		512	D
1/7/26 13:51	1/5/26	INDV	Indivior Plc	X0	Health	Drug	Pharmaceutical Preparations	5	5	P	172	35.39	5	10	56	D
1/7/26 12:45	1/5/26	ACTU	Actuate Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-1,624	5.80	-280		2,354	I
1/6/26 21:36	1/2/26	SYRE	Spyre Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	3	S	-1,945	25.94	-75		702	D
1/6/26 21:30	12/11/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	10	19	P.dm	48,255	13.69	3,526	11	36,993	I
1/6/26 20:22	1/2/26	ATAI	Ataibeckley Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-154	3.90	-40		7,663	D
1/6/26 20:00	1/2/26	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	6	6	S.dm	-328	6.63	-50		1,169	D
1/6/26 19:47	1/2/26	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	5	10	S.d	-3,864	132.68	-29		240	D
1/6/26 17:30	1/5/26	PCRX	Pacira Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	5	S.dm	-1,434	21.27	-67		294	D
1/6/26 17:00	1/5/26	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	11	36	M.d	1,948	5.98	326	5	6,869	D
1/6/26 17:00	1/2/26	AMRN	Amarin Corp Plcuk	X0	Health	Drug	Pharmaceutical Preparations	4	4	M.d	0	0.00	14	32	56	D
1/6/26 16:54	12/16/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	7	46	S.dm	-7,639	4.01	-1,907		6,980	D
1/6/26 16:30	1/2/26	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	M.d	23	6.65	4	88	7	D
1/6/26 16:30	1/2/26	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	S.d	-23	6.65	-4		7	D
1/6/26 16:30	12/8/25	FULC	Fulcrum Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	S	-58,765	13.96	-4,209		6,549	I
1/6/26 16:16	1/5/26	CTNM	Contineum Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.d	-154	9.92	-16		171	D
1/6/26 16:05	1/2/26	SLGL	Sol-Gel Technologies Ltd.	L3	Health	Drug	Pharmaceutical Preparations	1	9	P.m	3,658	41.12	89	24	457	I
1/6/26 16:05	1/2/26	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	5	P	69	3.20	22	1	1,983	D
1/6/26 16:02	12/24/25	LYEL	Lyell Immunopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	5	S.m	-88	29.91	-3		107	D
1/5/26 21:50	1/5/26	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	14	S.dm	-33,921	60.30	-563		4,874	D
1/5/26 20:31	1/5/26	VKTX	Viking Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	9	S.d	-16,038	32.59	-492		3,264	D
1/5/26 16:32	12/2/25	ACRS	Aclaris Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	M.dm	0	0.00	242	15	1,841	D
1/5/26 16:30	1/1/26	XLO	Xilio Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	6	M.d	6	0.0605	94	32	390	D
1/5/26 16:26	1/5/26	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	8	31	M.d	13,834	36.85	375	101	746	D
1/5/26 16:26	1/5/26	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	8	31	S.d	-13,834	36.85	-375		746	D
1/5/26 16:16	12/8/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	18	S.dm	-4,274	19.67	-217		489	D
1/5/26 16:15	1/2/26	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-8	0.8553	-9		398	D
1/5/26 16:07	1/2/26	RARE	Ultragenyx Pharmaceutical Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S	-187	29.60	-6		146	D
1/5/26 15:46	12/31/25	MNPR	Monopar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	4	4	M.d	449	22.82	20	5	419	D
1/5/26 08:00	12/31/25	HYPD	Hyperion Defi, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	5	P.m	611	3.23	189	37	698	D
1/5/26 07:00	12/31/25	RNXT	Renovorx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	7	P.m	55	0.8557	64	6	1,129	D
1/2/26 21:00	1/2/26	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	12	S.d	-1,156	17.59	-66		815	D
1/2/26 18:49	1/2/26	XENE	Xenon Pharmaceuticals Inc.	A1	Health	Drug	Pharmaceutical Preparations	1	4	M.dm	3,224	30.61	105		46	D
1/2/26 18:49	1/2/26	XENE	Xenon Pharmaceuticals Inc.	A1	Health	Drug	Pharmaceutical Preparations	1	4	S.dm	-3,224	30.61	-105		46	D
1/2/26 18:00	1/1/26	VTRS	Viatris Inc	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	0	0.00	25	239	36	D
1/2/26 17:25	12/31/25	VRDN	Viridian Therapeutics, Inc.De	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-10,071	22.05	-457		3,914	D
1/2/26 17:13	12/30/25	SLRX	Salarius Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S	-20	0.7895	-25		25	M
1/2/26 16:30	12/30/25	ANNX	Annexon, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	P.m	8,846	3.74	2,368	32	9,816	D
1/2/26 16:15	12/30/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	3	6	M.d	626	11.28	56	132	98	D
1/2/26 16:15	12/31/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	3	6	S.d	-626	11.28	-56		98	D
1/2/26 16:10	12/31/25	COCP	Cocrystal Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	5	P.m	153	0.9596	159	9	1,866	I
1/2/26 16:07	1/1/26	FBRX	Forte Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	M.d	255	22.54	11	10	125	D
1/2/26 16:05	12/31/25	PHIO	Phio Pharmaceuticals Corp.	DE	Health	Drug	Pharmaceutical Preparations	1	4	P	22	1.12	20	7	291	D
1/2/26 16:00	12/30/25	CUE	Cue Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	100	0.3080	324		324	D
12/31/25 16:33	12/9/25	IRD	Opus Genetics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-8,924	2.14	-4,164		7,500	D
12/31/25 16:05	12/29/25	CVKD	Cadrenal Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S.m	-154	9.63	-16		406	D
12/30/25 18:47	12/19/25	IMNM	Immunome Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	5	P	9,784	21.66	452	10	5,062	D
12/30/25 17:54	12/23/25	ALZN	Alzamend Neuro, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-11	2.10	-5		19	D
12/30/25 17:41	12/26/25	MRUS	Merus N.V.	P7	Health	Drug	Pharmaceutical Preparations	2	8	P.edm	235,854	3.01	78,308		72,840	I
12/30/25 16:33	12/26/25	CYPH	Cypherpunk Technologies Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	M.d	5,069	2.99	1,697		180	D
12/30/25 16:17	12/30/25	MBIO	Mustang Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	0	0.9639	0		1	D
12/30/25 16:02	9/30/25	VREOF	Vireo Growth Inc.	A1	Health	Drug	Pharmaceutical Preparations	1	1	M.d	0	0.00	200		138	D
12/30/25 16:01	12/26/25	COGT	Cogent Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	S	-12,179	38.71	-315		515	D
12/29/25 20:44	12/5/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	11	M.dm	34,709	40.96	847	13	7,403	D
12/29/25 20:44	12/5/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	11	S.dm	-34,709	40.96	-847		7,403	D
12/29/25 20:06	12/22/25	RIGL	Rigel Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	140	21.51	7	11	64	D
12/29/25 19:31	12/23/25	BNTC	Benitec Biopharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	3	P.m	22,442	13.42	1,672	948	1,848	I
12/29/25 18:42	12/22/25	EOLS	Evolus, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-92	7.15	-13		711	D
12/29/25 16:30	12/24/25	PTN	Palatin Technologies Inc	NJ	Health	Drug	Pharmaceutical Preparations	1	1	S	-9	16.75	-1		63	D
12/29/25 16:23	12/23/25	TXMD	Therapeuticsmd, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	1	P	14	1.67	8	29	38	D
12/23/25 20:09	12/22/25	OKUR	Onkure Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-1	2.97	0		24	D
12/23/25 16:16	12/19/25	FOLD	Amicus Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	14	S.dm	-5,885	9.39	-627		2,422	D
12/23/25 16:02	12/19/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	2	4	M.dm	5,511	14.04	392	120	720	D
12/23/25 16:02	12/19/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.dm	-5,511	14.04	-392		720	D
12/23/25 14:55	12/19/25	CAPR	Capricor Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	4	1.39	3	27	14	D
12/22/25 20:48	12/22/25	PGEN	Precigen, Inc.	VA	Health	Drug	Pharmaceutical Preparations	2	3	S.m	-21,090	4.13	-5,102		124,057	I
12/22/25 16:15	12/19/25	LITS	Lite Strategy, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	P	1,067	1.38	773	26	3,775	D
12/22/25 07:07	11/7/25	EVMN	Evommune, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	P.d	70,017	16.00	4,376	45	14,016	I
12/19/25 17:00	12/19/25	SVRA	Savara Inc	DE	Health	Drug	Pharmaceutical Preparations	3	3	S.d	-138	4.36	-32		2,722	D
12/19/25 17:00	12/17/25	ADTX	Aditxt, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	0	2.50	0		0	D
12/19/25 16:30	12/18/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	9	M.d	1,040	8.43	123	17	847	D
12/19/25 16:30	12/18/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	9	S.d	-1,040	8.43	-123		847	D
12/19/25 16:15	12/17/25	VTYX	Ventyx Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	M.d	463	2.19	212	8	2,862	D
12/19/25 16:15	12/18/25	VTYX	Ventyx Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.d	-463	2.19	-212		2,862	D
12/19/25 16:05	12/17/25	PVLA	Palvella Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	4	M.d	856	49.73	17		0	D
12/19/25 16:05	12/17/25	PVLA	Palvella Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	4	S.d	-856	49.73	-17	-100	0	D
12/18/25 20:05	12/16/25	SRPT	Sarepta Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-294	22.31	-13		193	D
12/18/25 17:23	12/17/25	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	3	8	M.dm	1,391	21.09	66	23	353	D
12/18/25 17:23	12/17/25	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	3	8	S.dm	-1,391	21.09	-66		353	D
12/18/25 16:19	12/16/25	ORGO	Organogenesis Holdings Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	4	S.m	-3,796	4.31	-881		12,249	D
12/18/25 16:04	12/16/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	6	13	S.d	-24,465	23.41	-1,045		788	D
12/18/25 15:13	12/16/25	APLT	Applied Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-5	0.1120	-43		65	D
12/17/25 16:23	12/15/25	LFVN	Lifevantage Corp		Health	Drug	Pharmaceutical Preparations	2	3	P	336	6.80	49	28	229	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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