Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	Title	#f	T	TVal	Price	Qty	oc	Own	H
10/15/25 20:56	10/13/25	LVTX	Lava Therapeutics Nv	P7	Health	Drug	Pharmaceutical Preparations	Cooperatieve Gilde Healthcare IV U.A.	P7	T		2	S.m	-917	1.52	-602		5,294	D
10/15/25 20:12	10/10/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dunlop A. Sinclair	MA	D		5	S	-4,946	29.57	-167		302	M
10/15/25 20:07	9/12/25	BYSI	Beyondspring Inc.		Health	Drug	Pharmaceutical Preparations	Decheng Capital China Life Sciences Usd Fund Iii, L.P.	CA	T		16	S.m	-1,792	2.48	-723		4,488	I
10/15/25 19:04	10/13/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Levy Adam Scott	PA	O	CFO,Secr	8	S.m	-3,453	14.69	-235		255	D
10/15/25 19:04	10/13/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Congleton Jon	PA	DO	CEO	8	S.m	-3,160	14.51	-218		976	D
10/15/25 19:04	10/15/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rodman David Malcom	PA	O	Chief Me	11	S.d	-3,018	18.25	-165		141	D
10/15/25 18:47	10/15/25	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	Hopkinson Craig C.	MA	O	EVP R,D,	8	S.dm	-20,144	32.84	-613		99	D
10/15/25 18:33	10/10/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Booth Bruce	MA	D		3	S.m	-9,793	30.30	-323		3,615	I
10/15/25 18:31	10/10/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Swisher Daniel N Jr	CA	D		15	S.d	-1,922	62.09	-31	-100	0	D
10/15/25 18:00	10/13/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mazumdar Claire	MA	DO	CEO	1	S.dm	-467	18.88	-25		310	D
10/15/25 16:36	10/13/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Schundler Russell	NC	O	GC	13	S.d	-857	15.17	-56		597	D
10/15/25 16:34	10/13/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Kaseta Michael	NC	O	CFO,COO	15	S.d	-2,392	17.91	-134		412	D
10/15/25 16:34	10/13/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Moomaw Scott	NC	O	Chief Co	13	S.d	-2,539	24.25	-105		225	D
10/15/25 16:33	10/13/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Saggar Rajeev	NC	O	Chief Me	13	S.d	-1,205	18.90	-64		273	D
10/15/25 16:32	10/13/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Boyle Dana	NC	O	Chief Ac	4	S	-75	19.89	-4		187	D
10/15/25 16:32	10/6/25	SPRB	Spruce Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Parkman Healthcare Partners LLC	CT	T		2	S	-10	19.14	-1		1	I
10/15/25 16:31	9/2/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Jeffs Roger	NC	DO	CEO	11	S.dm	-15,591	61.36	-254		2,764	D
10/15/25 16:31	10/13/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Adair Jason	NC	O	Chief Bu	19	S.dm	-1,115	21.58	-52		194	D
10/15/25 16:30	8/26/24	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	47	S.dm	-114,101	351.87	-324		647	D
10/15/25 16:30	10/13/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Balcom Alexandra	MA	O	CFO	12	S.dm	-16,416	85.68	-192		62	D
10/15/25 16:30	10/13/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Benkowitz Michael	MD	O	P,COO	28	S.dm	-151,596	385.98	-393		3	I
10/15/25 16:30	8/7/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pelish Henry E.	MA	O	Chief Sc	9	S.dm	-7,428	88.73	-84		66	D
10/15/25 16:30	10/13/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Krepp Sarah	NC	O	Chief Hu	3	S	-84	18.33	-5		143	D
10/15/25 13:24	10/15/25	KROS	Keros Therapeutics, Inc.		Health	Drug	Pharmaceutical Preparations	Adar1 Capital Management, LLC	TX	T		1	S	-95,659	17.75	-5,389	-100	0	I
10/14/25 21:00	10/9/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Venker Eric	X0	O	P,Immuno	17	S.dm	-77,627	12.85	-6,042		1,654	D
10/14/25 20:11	10/10/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cheng Andrew	CA	DO	P,CEO	18	S.dm	-22,840	40.75	-560		716	D
10/14/25 19:49	10/13/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Cook Meredith	MN	O	SVP,GC,S	17	S	-390	67.76	-6		82	D
10/14/25 18:00	10/10/25	BGMS	Bio Green Med Solution, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fitters Diversified Berhad	N8	T		2	S	-1,022	5.28	-193		557	D
10/14/25 16:31	10/9/25	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	Bunn Paul A.	MA	D		1	S	-75	9.06	-8		8	D
10/14/25 16:05	10/9/25	CVKD	Cadrenal Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Szot Matthew K	FL	O	CFO	5	S.m	-278	14.03	-20		31	D
10/14/25 16:05	10/9/25	CVKD	Cadrenal Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pham Quang X	FL	DOT	CEO,CB	5	S.m	-278	14.05	-20		413	D
10/14/25 16:01	12/16/24	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	Waddill William D.	CA	D		8	S.dm	-2,815	50.73	-55		54	D
10/14/25 16:00	7/24/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	Lilly Endowment Inc	IN	T		41	S.e	-3,347,312	860.38	-3,890		98,402	D
10/14/25 13:16	8/18/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	Moreadith Randall	AL	O	Chief Sc	11	S.dm	-641	6.16	-104	-100	0	D
10/14/25 12:15	10/13/25	RARE	Ultragenyx Pharmaceutical Inc.	DE	Health	Drug	Pharmaceutical Preparations	Horn Howard	CA	O	CFO	3	S	-716	41.66	-17		106	D
10/10/25 19:17	10/10/25	ZVRA	Zevra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McFarlane Neil F.	FL	DO	P,CEO	2	S.dm	-938	8.43	-111		222	D
10/10/25 18:17	9/12/25	BGMS	Bio Green Med Solution, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kua Khai Loon	N8	T		2	S.m	-400	6.04	-66		385	D
10/10/25 17:40	9/4/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kumar Neil	CA	DO	CEO	13	S.dm	-52,350	38.53	-1,359		6,906	I
10/10/25 17:33	10/9/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Khattar Jack A.	MD	DO	P,CEO	15	S.dm	-27,668	42.17	-656		2,212	D
10/10/25 17:23	10/9/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Raben David	MA	O	Chief Me	1	S.d	-406	18.45	-22		35	D
10/10/25 17:22	10/9/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hyep Ivan	MA	O	CFO	2	S.dm	-670	18.21	-37		145	D
10/10/25 16:56	10/8/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Lee Chan Henry	V8	O	SVP,GC	11	S.d	-12,008	310.97	-39		278	D
10/10/25 16:30	10/8/25	ALZN	Alzamend Neuro, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ault Milton C III	NV	D		11	S.dm	-2,218	2.45	-906		124	I
10/10/25 16:21	10/9/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Newhall Charles W III	MD	D		5	S.d	-1,927	46.21	-42		134	D
10/10/25 16:18	10/8/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Scadden David	MA	D		5	S.d	-89	40.66	-2		18	D
10/10/25 16:12	10/8/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kaye Edward M. Md	MA	D		11	S.dm	-4,841	24.51	-198		183	D
10/10/25 16:01	10/8/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	Anderman Todd	MA	O	GC	1	S	-137	12.34	-11		88	D
10/9/25 18:58	9/8/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rolph Timothy	CA	O	Chief Sc	19	S.dm	-9,382	49.10	-191		198	D
10/9/25 17:51	10/7/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Guyer William	CA	O	Chief De	17	S.dm	-14,050	63.86	-220		6	D
10/9/25 17:21	10/7/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Patel Anish	CO	O	COO	13	S.dm	-3,173	22.63	-140		394	I
10/9/25 16:22	8/19/25	HOOK	Hookipa Pharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	Peters Malte	NY	DO	CEO	2	S	-48	0.8745	-54		80	D
10/9/25 16:07	10/7/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bitterman Kevin	MA	D		7	S.m	-11,618	65.68	-177		1,148	I
10/9/25 13:37	10/8/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Degnan Chris	NJ	O	CFO	1	S.d	-37	16.85	-2		2	D
10/8/25 21:08	10/6/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tabuteau Herriot	NY	DOT	CEO	2	S.dm	-12,780	118.04	-108		7,352	D
10/8/25 19:48	10/1/25	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hunter Heather	MI	O	SVP,COO	1	S	-3	1.19	-3		135	D
10/8/25 19:08	10/6/25	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jarrett Jennifer	CA	O	COO	1	S.dm	-750	14.92	-50		214	D
10/8/25 18:37	10/6/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Swayze Eric	CA	O	EVP Rese	8	S.adm	-3,243	57.07	-57		48	D
10/8/25 18:37	10/6/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	O'Neil Patrick R.	CA	O	EVP CLO,	11	S.adm	-14,432	61.64	-234		64	D
10/8/25 18:36	10/6/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Monia Brett P	CA	DO	CEO	11	S.ad	-17,851	51.30	-348		220	D
10/8/25 18:36	10/6/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Baroldi Joseph	CA	O	EVP,Chie	7	S.d	-4,094	58.50	-70		35	D
10/8/25 17:37	10/6/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Piscitelli Dominic	CA	O	CFO	7	S.dm	-850	10.65	-80		107	D
10/8/25 17:35	10/6/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chacko Jacob	CA	DO	P,CEO	4	S.dm	-3,069	11.17	-275		779	D
10/8/25 17:33	10/6/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cohlhepp Ryan	MA	DO	P,COO	1	S.dm	-912	18.06	-51		203	D
10/8/25 16:16	10/7/25	CARM	Carisma Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Klichinsky Michael	PA	O	Chief Sc	2	S.dm	-139	0.2565	-541	-100	0	D
10/8/25 16:10	8/5/25	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	Taiwan Carbon Nano Technology Corp	F5	T		6	S.m	-167	1.94	-86		5,471	D
10/7/25 17:08	9/9/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Malik Fady Ibraham	CA	O	EVP Rese	36	S.d	-7,762	50.12	-155		141	D
10/7/25 16:26	10/3/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Allan Jonathan	MA	O	GC,Corp	7	S.dm	-1,277	17.01	-75		35	D
10/7/25 16:11	10/3/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mosbrooker Eric	CA	O	Chief Co	3	S.d	-6,370	44.26	-144		55	D
10/6/25 17:13	10/2/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	Kaiser Peter	MA	O	Chief De	5	S	-211	9.79	-22		213	D
10/6/25 17:10	10/2/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	Heier Jeffrey S.	MA	O	Chief Sc	5	S	-222	9.83	-23		269	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Lee Kevin	X0	DO	CEO	6	S.dm	-437	12.42	-35		492	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Skynner Michael	X0	O	CTO	6	S.dm	-143	12.34	-12		124	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Milnes Alistair	X0	O	COO	6	S.dm	-169	12.19	-14		100	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Hannay Michael Charles Ferguson	X0	O	CHIEF PR	6	S.dm	-57	11.97	-5		55	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Young Alethia	X0	O	CFO	4	S.d	-27	11.73	-2		46	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Thompson Travis Alvin	X0	O	Chief Ac	7	S.dm	-238	19.68	-12		32	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Swanton Robert Charles	X0	D		1	S	-1	8.55	0		15	D
10/6/25 15:15	5/19/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Edwards Larry Todd	CA	O	See Rema	4	S	-260	14.56	-18		183	D
10/3/25 21:58	7/8/25	ELTP	Elite Pharmaceuticals Inc /Nv/	NJ	Health	Drug	Pharmaceutical Preparations	Plassche Douglas	NJ	O	EVP Oper	3	S.m	-1,177	0.5517	-2,134		3,500	D
10/3/25 21:27	2/3/25	JAZZ	Jazz Pharmaceuticals Plc	L2	Health	Drug	Pharmaceutical Preparations	Cozadd Bruce C	L2	D		12	S.m	-3,876	129.21	-30		464	D
10/3/25 18:15	10/1/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hamilton James C	CA	O	Chief Me	5	S.m	-2,374	25.60	-93		272	D
10/3/25 17:24	10/1/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Belanoff Joseph K	CA	DO	CEO	9	S.dm	-18,904	78.45	-241		3,019	I
10/3/25 17:17	10/1/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Lyon Joseph Douglas	CA	O	See Rema	15	S.dm	-23,989	91.77	-261		10	D
10/3/25 17:15	10/1/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Maduck Sean	CA	O	See Rema	12	S.dm	-23,957	79.86	-300		118	D
10/3/25 17:14	10/2/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Poulton Jeffrey V.	MA	O	EVP,CFO	7	S.d	-4,298	346.38	-12		54	D
10/3/25 17:14	10/2/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Greenstreet Yvonne	MA	DO	CEO	11	S.dm	-38,057	303.03	-126		99	D
10/3/25 17:14	10/2/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Tanguler Tolga	MA	O	EVP,Chie	7	S.d	-3,804	368.12	-10		29	D
10/3/25 17:13	10/2/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Fitzgerald Kevin Joseph	MA	O	CSO,EVP,	8	S.dm	-10,057	283.98	-35		26	D
10/3/25 17:12	10/2/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Garg Pushkal	MA	O	EVP Chie	10	S.dm	-24,828	298.04	-83		25	D
10/3/25 17:02	10/1/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Watanabe Todd	CA	DO	See Rema	11	S.dm	-2,538	14.87	-171		1,161	D
10/3/25 17:01	10/1/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Welgus Howard G.	CA	D		17	S.d	-2,137	12.62	-169		205	D
10/3/25 16:56	9/3/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Abate Kristin	MA	O	Chief Ac	5	S	-7	5.85	-1		10	D
10/3/25 16:45	10/1/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Kozarich John W	FL	D		4	S	-338	144.72	-2		46	D
10/3/25 16:41	9/2/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pizzuti Dana	CA	O	Chief Me	10	S.d	-4,399	41.02	-107		96	D
10/3/25 16:30	9/2/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Young Jonathan	CA	O	COO	21	S.d	-9,139	36.71	-249		313	D
10/3/25 16:25	10/1/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ticho Barry	MA	O	Chief Me	17	S.dm	-1,972	13.04	-151		61	D
10/3/25 16:20	10/2/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Chen Yajing	MA	O	CFO	11	S.d	-869	31.57	-28		27	D
10/3/25 16:07	10/2/25	VRTX	Vertex Pharmaceuticals Inc / Ma	MA	Health	Drug	Pharmaceutical Preparations	Biller Jonathan	MA	O	EVP,GC	4	S	-3,074	453.26	-7		18	D
10/2/25 19:36	10/1/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Wender Joseph H	CA	D		3	S.m	-4,325	59.41	-73		109	I
10/2/25 19:24	10/1/25	TERN	Terns Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kuriakose Emil	CA	O	Chief Me	4	S	-39	5.40	-7		54	D
10/2/25 17:04	10/1/25	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Petersen Floyd F.	CA	D		11	S.d	-403	36.66	-11		81	D
10/2/25 16:47	9/30/25	ONC	Beigene, Ltd.		Health	Drug	Pharmaceutical Preparations	Baker Bros. Advisors LP	NY	D		3	S.m	-385,792	154.30	-2,500		9,438	I
10/2/25 16:30	8/21/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	16	S.d	-55,309	326.50	-169		37	D
10/2/25 16:15	9/30/25	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Klee Justin B.	MA	DO	Co-CEO	6	S	-651	6.92	-94		3,355	D
10/2/25 16:15	9/30/25	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mazzariello Gina	MA	O	GC	7	S.m	-466	7.03	-66		188	D
10/2/25 16:15	9/30/25	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Frates James M	MA	O	CFO	2	S	-192	8.97	-21		318	D
10/2/25 16:15	9/30/25	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cohen Joshua B	MA	DO	Co-CEO	6	S	-649	6.91	-94		3,355	D
10/2/25 16:15	9/30/25	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bedrosian Camille L	MA	O	Chief Me	4	S	-285	6.90	-41		194	D
10/1/25 20:14	8/25/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Noci Darlene	MA	O	Chief De	14	S.dm	-7,044	77.40	-91		48	D
10/1/25 19:17	10/1/25	XENE	Xenon Pharmaceuticals Inc.	A1	Health	Drug	Pharmaceutical Preparations	Mortimer Ian	A1	DO	P,CEO,IN	2	S.dm	-3,218	40.23	-80		46	D
10/1/25 17:22	9/29/25	MLTX	Moonlake Immunotherapeutics	E9	Health	Drug	Pharmaceutical Preparations	Chen Bihua	MA	H	Former 1	1	S.m	-46,868	7.21	-6,500		1,994	I
10/1/25 17:16	12/9/24	PRGO	Perrigo Co Plc	L2	Health	Drug	Pharmaceutical Preparations	Kindler Jeffrey B	MI	D		2	S.m	-1,102	5.74	-192		351	D
10/1/25 16:57	6/16/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Meisner Lara	MA	O	GC	4	S.d	-1,867	12.91	-145	-100	0	D
10/1/25 16:55	9/30/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Geary Richard S	CA	O	EVP,Chie	8	S.dm	-5,237	57.26	-91		99	D
10/1/25 16:46	9/29/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hohl Benjamin	CO	O	CFO	26	S.dm	-2,094	23.58	-89		23	D
10/1/25 16:44	9/29/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Tessari Eben	X0	O	COO	19	S.dm	-18,138	30.72	-590		120	D
10/1/25 16:30	7/9/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	O'Malley Brendan M.	OH	O	SVP,GC	4	S	-227	5.98	-38		378	D
10/1/25 16:30	7/9/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Seshadri Vishwas	OH	DO	CEO	4	S.m	-1,103	5.83	-189		1,355	D
10/1/25 16:30	7/22/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Vazzano Joseph Walter	OH	O	CFO	5	S	-438	6.37	-69		491	D
10/1/25 16:26	9/2/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Blum Robert I	CA	DO	P,CEO	31	S.d	-13,566	46.88	-289		443	D
10/1/25 16:24	10/1/25	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chole Timothy	MI	O	SVP,CCO	6	S	-17	1.26	-13		128	D
10/1/25 16:23	10/1/25	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Neri Jesse	MI	O	SVP,CFO	4	S	-3	0.9828	-4		127	D
10/1/25 16:22	10/1/25	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Strobeck Mark	MI	DO	P,CEO	6	S	-39	1.23	-32		338	D
10/1/25 16:10	9/9/25	PAHC	Phibro Animal Health Corp	DE	Health	Drug	Pharmaceutical Preparations	Bendheim Jack	NJ	DOT	P,CEO	3	S.dm	-1,974	40.46	-49		78	I
10/1/25 16:00	9/16/24	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Loumeau Eric J	CA	O	GC	2	S.dm	-731	35.27	-21		9	D
9/30/25 18:59	9/29/25	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Azoy Alexander	CA	O	Chief Ac	4	S	-79	13.23	-6		30	D
9/30/25 17:56	9/26/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jones Cecilia	MA	O	CFO	4	S.d	-399	38.98	-10		34	D
9/30/25 17:53	9/26/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lyssikatos Joseph P	CO	O	CHIEF SC	20	S.dm	-4,731	23.50	-201		1,117	I
9/30/25 17:51	9/26/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kintz Samuel	CO	DO	P,CEO	20	S.m	-3,971	23.07	-172		1,253	I
9/30/25 17:44	9/30/25	PGEN	Precigen, Inc.	VA	Health	Drug	Pharmaceutical Preparations	Kirk Randal J	VA	DT		2	S.dm	-24,824	3.65	-6,810		128,722	I
9/30/25 16:42	9/26/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Struthers Richard Scott	CA	DO	P,CEO	3	S	-1,349	43.04	-31		1,298	I
9/30/25 16:41	9/26/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fust Matthew K	CA	D		1	S.d	-716	44.75	-16		23	D
9/30/25 16:09	8/26/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cloonan Michael	MA	DO	P,CEO	3	S.dm	-1,921	25.61	-75		547	D
9/29/25 19:30	9/29/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Powl Brian T.	CA	O	Chief Co	2	S	-92	8.78	-10		100	D
9/29/25 19:30	9/29/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bair Teresa Brophy	CA	O	GC	3	S	-145	8.24	-18		148	D
9/29/25 19:30	9/29/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ford Kathleen	CA	O	COO	4	S	-94	8.72	-11		63	D
9/29/25 19:30	9/29/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Leoni Mollie	CA	O	Chief Me	2	S	-149	8.63	-17		158	D
9/29/25 19:30	9/5/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Wilson Troy Edward	CA	DO	P,CEO	5	S.d	-6,206	31.19	-199		1,583	D
9/29/25 19:30	9/29/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Doyle Thomas James	CA	O	SVP,Fina	2	S	-80	8.38	-9		110	D
9/29/25 16:26	9/26/25	AQST	Aquestive Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Barber Daniel	NJ	DO	P,CEO	2	S	-554	6.03	-92		1,015	D
9/29/25 16:26	9/26/25	AQST	Aquestive Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Boyd Peter E.	NJ	O	See Rema	2	S	-143	5.70	-25		288	D
9/29/25 16:15	9/25/25	TNGX	Tango Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Third Rock Ventures Iv, L.P.	MA	T		16	S.m	-45,058	8.44	-5,338		18,651	D
9/26/25 19:43	9/24/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Kapusta Matthew C	P7	DO	CEO,MD	5	S.dm	-11,565	29.54	-392		651	D
9/26/25 19:37	9/24/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Klemt Christian	P7	O	CFO	5	S.dm	-1,260	25.67	-49		218	D
9/26/25 15:53	9/24/25	MNPR	Monopar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	Tactic Pharma LLC	IL	T		2	S	-36,167	61.98	-584		822	D
9/25/25 16:31	11/1/24	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Causey Christopher	MD	D		6	S.d	-3,800	354.44	-11		5	D
9/24/25 19:42	9/22/25	OKUR	Onkure Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Saccomano Nicholas A	CO	DO	P,CEO	3	S.m	-3	2.87	-1		4	D
9/24/25 19:41	9/22/25	OKUR	Onkure Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Leverone Jason A.	CO	O	CFO	3	S.m	-11	2.87	-4		13	D
9/24/25 19:00	2/3/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Bush Tia L	X0	O	Chief Te	4	S.dm	-2,549	20.69	-123		148	D
9/24/25 17:11	9/23/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Aryeh Jason	FL	D		1	S	-1,708	170.81	-10		126	D
9/24/25 16:30	9/22/25	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	Calkins Daniel	MA	O	CFO	11	S.m	-114	7.25	-16		114	D
9/24/25 16:05	5/5/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	Reed Elizabeth E	CA	O	GC,GC	6	S.d	-817	21.11	-39		90	D
9/23/25 17:32	9/22/25	XOMA	Xoma Royalty Corp	NV	Health	Drug	Pharmaceutical Preparations	Burns Thomas M.	CA	O	SVP,Fina	3	S.d	-715	29.06	-25		40	D
9/23/25 16:57	9/22/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hughes Steven George	CA	O	Chief Me	7	S.d	-4,225	41.23	-102		82	D
9/23/25 16:33	9/19/25	LVTX	Lava Therapeutics Nv	P7	Health	Drug	Pharmaceutical Preparations	Versant Venture Capital Vi, L.P.	CA	T		3	S.m	-7,538	1.40	-5,376		6,410	M
9/22/25 19:00	9/22/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jacobson Mark L.	NY	O	COO	5	S.dm	-17,417	102.94	-169		6	D
9/22/25 17:14	9/19/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Davis Krista	MN	O	SVP,CHRO	6	S	-561	73.54	-8		69	D
9/19/25 18:23	9/18/25	RARE	Ultragenyx Pharmaceutical Inc.	DE	Health	Drug	Pharmaceutical Preparations	Huizenga Theodore Alan	CA	O	SVP,Chie	4	S.d	-50	41.73	-1		50	D
9/19/25 16:49	9/19/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Olian Judy D.	MD	D		3	S	-1,972	375.59	-5		6	D
9/19/25 16:05	9/4/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ceesay Abraham	MA	DO	CEO	2	S	-2,075	26.34	-79		722	D
9/18/25 21:30	9/16/25	OLMA	Olema Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Harmon Cyrus	CA	D		6	S.m	-965	10.01	-96		903	M
9/18/25 18:16	6/13/25	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	Stuglik Brian M	MA	D		9	S.dm	-84	3.73	-23		197	D
9/18/25 18:14	9/16/25	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	Gagnon Robert E.	MA	D		7	S.dm	-11	5.16	-2		42	D
9/18/25 18:11	9/16/25	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	Paterson Dan	MA	DO	P,CEO	15	S.m	-654	6.93	-94		462	D
9/18/25 16:45	7/9/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Oyler John	V8	DO	CEO	12	S.dm	-83,651	253.33	-330		54,270	D
9/18/25 16:06	9/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Looker Benjamin	MI	O	GC	3	S	-26	1.89	-14		401	D
9/18/25 16:06	9/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Koenig Sheldon L.	MI	DO	P,CEO	5	S	-189	1.92	-99		1,572	D
9/18/25 16:06	9/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Halladay Benjamin	MI	O	CFO	8	S	-41	1.96	-21		482	D
9/18/25 16:01	9/16/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Watson David O.	MA	O	GC	11	S	-1,617	26.18	-62		228	D
9/17/25 20:08	9/15/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chopas James George	MA	O	VP,Chief	8	S	-130	30.64	-4		54	D
9/17/25 19:39	9/16/25	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	Tross Stuart A	CT	O	Chief Pe	4	S	-1,317	6.36	-207		1,047	D
9/17/25 16:31	8/15/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Porter James Richard	MA	DO	P,CEO	13	S.d	-27,282	79.94	-341		249	D
9/17/25 16:30	9/15/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Singh Raman	NC	D		2	S.d	-1,396	26.32	-53		31	D
9/17/25 16:15	9/15/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bredt David	MA	O	Chief Sc	7	S	-800	13.45	-60		469	D
9/17/25 16:03	9/15/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McCarthy Teresa	CA	O	CHRO	11	S.d	-6,825	40.17	-170		105	D
9/16/25 21:45	12/6/24	OGEN	Oragenics Inc	FL	Health	Drug	Pharmaceutical Preparations	Dunton Alan W	FL	D		2	S.d	-131	13.05	-10		66	D
9/16/25 18:16	7/29/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Accardi Mario Alberto	X0	O	P,Orexin	4	S.d	-652	16.93	-38		216	D
9/16/25 18:00	9/15/25	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Schneyer Mark C.	CA	O	EVP,CFO	10	S.d	-1,183	20.18	-59		63	D
9/16/25 16:35	9/15/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Paulson Richard A.	MA	DO	P,CEO	13	S	-112	2.39	-47		1,150	D
9/16/25 16:34	9/15/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mano Michael	MA	O	SVP,GC,S	3	S	-22	3.14	-7		274	D
9/16/25 16:33	9/15/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Poulton Stuart	MA	O	EVP,Chie	5	S	-33	2.51	-13		327	D
9/16/25 16:32	9/15/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rangwala Reshma	MA	O	EVP,Chie	3	S	-28	6.29	-4		29	D
9/16/25 16:31	9/15/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cheng Sohanya Roshan	MA	O	EVP,Chie	3	S	-28	3.03	-9		404	D
9/15/25 18:37	8/15/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Hussain Iqbal J	X0	O	GC	11	S.dm	-2,978	17.34	-172		131	D
9/15/25 17:39	9/12/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mottola Frank	MD	O	SVP,Chie	3	S.d	-1,407	41.39	-34		15	D
9/15/25 16:26	9/12/25	MRSN	Mersana Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Huber Martin H. Jr.	MA	DO	P,CEO	3	S.d	-106	1.86	-57		123	D
9/15/25 16:23	6/10/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Schaeffer Orlov S Nicole	NJ	O	Chief Pe	12	S.dm	-41,777	91.36	-457		121	D
9/15/25 16:22	9/12/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Sharoky Melvin Md	NJ	D		3	S	-3,965	132.16	-30		334	M
9/15/25 12:45	9/12/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Callicutt Jack W	GA	O	CFO	2	S.d	-92	1.88	-49		8	D
9/15/25 12:45	9/12/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Lewis Joel	GA	DO	P,CEO	2	S.d	-139	1.98	-70		899	D
9/12/25 21:45	9/12/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	Todisco Joseph	NJ	O	CEO	1	S.d	-650	13.00	-50		509	D
9/12/25 20:39	9/11/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yale Catriona	CA	O	Chief De	24	S.dm	-11,919	43.87	-272		96	D
9/12/25 20:38	9/11/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	White William Richard	CA	O	CFO	17	S.dm	-9,233	28.77	-321		62	D
9/12/25 20:00	9/11/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Brege Laura	CA	D		2	S.d	-1,580	50.23	-31		31	D
9/12/25 20:00	9/12/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bjerkholt Eric	CA	O	CFO	2	S.d	-728	41.42	-18		40	D
9/12/25 18:00	9/11/25	VTRS	Viatris Inc	DE	Health	Drug	Pharmaceutical Preparations	Le Goff Corinne	PA	O	Chief Co	1	S	-72	10.25	-7		35	D
9/12/25 17:30	9/11/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Hariri Robert J	TN	D		6	S.dm	-405	8.44	-48		51	D
9/12/25 17:09	9/11/25	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	Persky Marla	IL	D		1	S	-120	7.72	-16		148	D
9/12/25 17:09	9/10/25	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	D		9	S.dm	-50,050	15.14	-3,305		22,582	I
9/12/25 16:42	9/11/25	TGTX	Tg Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lonial Sagar	NC	D		3	S.m	-1,257	24.28	-52		105	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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