Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	Title	#f	T	TVal	Price	Qty	oc	Own	H
7/31/26 18:00	7/30/26	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Thompson Elizabeth H.Z.	CA	O	EVP,Head	2	S.d	-506	25.33	-20		19	D
7/31/26 16:34	7/29/26	KNSA	Kiniksa Pharmaceuticals International, Plc		Health	Drug	Pharmaceutical Preparations	Cole G Bradley		D		1	S	-299	81.43	-4		7	D
7/31/26 16:26	7/31/26	PGEN	Precigen, Inc.	VA	Health	Drug	Pharmaceutical Preparations	Thomasian Harry Jr.	MD	O	CFO	3	S.m	-1,902	5.56	-342		555	D
7/31/26 16:18	7/30/26	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	142	S.edm	-681,694	523.95	-1,301		749	I
7/30/26 20:31	7/29/26	PRTA	Prothena Corp Public Ltd Co	L2	Health	Drug	Pharmaceutical Preparations	Kingston Anne Evans	CA	O	Chief St	1	S	-65	8.47	-8		56	D
7/30/26 20:30	7/29/26	PRTA	Prothena Corp Public Ltd Co	L2	Health	Drug	Pharmaceutical Preparations	Isaacs Michael John	CA	O	GC,Compa	1	S	-71	8.47	-8		36	D
7/30/26 17:58	7/30/26	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Van Houte Hans	CA	O	CFO	10	S.d	-729	14.38	-51		52	D
7/30/26 17:56	7/30/26	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ring Christine	CA	O	GC	17	S.d	-2,812	17.67	-159		57	D
7/30/26 17:50	7/30/26	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hansen Gwenn	CA	O	Chief Sc	7	S.d	-475	16.33	-29		121	D
7/30/26 16:42	7/28/26	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Poulton Stuart	MA	O	EVP,Chie	5	S	-12	7.58	-2		99	D
7/30/26 16:26	6/5/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Callos Andrew	CA	O	EVP,Chie	26	S.d	-16,913	63.54	-266		78	D
7/30/26 16:02	7/29/26	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Carey Stephen P.	NJ	O	SVP,CFO	6	S.d	-5,877	84.40	-70		186	D
7/29/26 21:00	6/24/26	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Venker Eric		O	P,Immuno	21	S.dm	-133,070	17.33	-7,678		1,655	D
7/29/26 20:07	7/29/26	VKTX	Viking Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lian Brian	CA	DO	P,CEO	4	S.d	-14,753	32.94	-448		2,572	D
7/29/26 20:06	7/29/26	VKTX	Viking Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Zante Greg	CA	O	CFO	4	S.d	-2,942	32.93	-89		212	D
7/29/26 20:06	7/29/26	VKTX	Viking Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mancini Marianna	CA	O	COO	4	S.d	-2,846	32.97	-86		423	D
7/29/26 16:30	7/27/26	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Boyle Dana	NC	O	Chief Ac	14	S.d	-2,369	36.72	-65		187	D
7/29/26 16:30	7/27/26	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Adair Jason	NC	O	Chief Bu	18	S.dm	-3,568	33.01	-108		217	D
7/29/26 16:15	7/27/26	DYN	Dyne Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kersten Dirk	MA	D		8	S.m	-38,572	20.56	-1,876		4,774	I
7/29/26 16:10	7/27/26	MLTX	Moonlake Immunotherapeutics	E9	Health	Drug	Pharmaceutical Preparations	Reich Kristian		O	Chief Sc	6	S.m	-8,136	17.45	-466		2,975	I
7/29/26 16:05	7/27/26	AVTX	Avalo Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Doyle Mittie	PA	O	Chief Me	9	S.dm	-2,931	19.65	-149		52	D
7/29/26 16:05	9/4/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ceesay Abraham	MA	DO	CEO	10	S	-4,310	28.36	-152		722	D
7/28/26 16:15	7/24/26	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Heyman Richard A.	CO	D		6	S.dm	-655	17.95	-36		428	M
7/27/26 19:30	7/23/26	OLMA	Olema Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Harmon Cyrus	CA	D		5	S.m	-949	14.29	-66		861	D
7/27/26 16:33	9/2/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Blum Robert I	CA	DO	P,CEO	27	S.d	-12,535	55.28	-227		434	D
7/27/26 16:08	7/23/26	IRD	Opus Genetics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yerxa Benjamin R	NC	DO	P	2	S	-61	4.11	-15		712	D
7/27/26 16:07	7/23/26	IRD	Opus Genetics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Schachle Joseph K	NC	O	COO	3	S	-58	4.42	-13		301	D
7/27/26 16:07	7/23/26	IRD	Opus Genetics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Magrath George	NC	DO	CEO	3	S	-205	4.72	-43		1,751	D
7/27/26 16:06	12/16/25	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	Gagnon Robert E.	MA	D		6	S	-73	4.33	-17		634	D
7/24/26 17:02	12/18/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Lewis William	NJ	DO	Chair,CE	32	S.dm	-56,976	112.34	-507		619	D
7/24/26 16:51	7/22/26	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Lee Chan Henry		O	SVP,GC	18	S.dm	-13,794	321.22	-43		347	D
7/24/26 16:30	7/22/26	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Bloch Stephen M	NC	D		11	S.m	-118,663	67.51	-1,758		2,255	I
7/23/26 18:39	6/26/26	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Warren Eric	PA	O	Chief Co	4	S.d	-2,900	25.42	-114		409	D
7/23/26 16:28	7/21/26	ACRV	Acrivon Therapeutics, Inc.		Health	Drug	Pharmaceutical Preparations	Miller Mary	MA	O	GC	1	S	-1	1.76	-1		82	D
7/23/26 16:09	9/9/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Malik Fady Ibraham	CA	O	EVP Rese	29	S.d	-4,897	58.00	-84		154	D
7/22/26 17:03	7/9/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Oyler John		DO	CEO	15	S.dm	-260,981	308.27	-847		54,270	D
7/22/26 16:30	7/22/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Vazzano Joseph Walter	OH	O	CFO	10	S.m	-990	6.04	-164		569	D
7/22/26 16:05	7/20/26	SGMT	Sagimet Biosciences Inc.	DE	Health	Drug	Pharmaceutical Preparations	Happel David	CA	DO	P,CEO	3	S	-1,160	8.19	-142		742	D
7/22/26 16:05	7/20/26	SGMT	Sagimet Biosciences Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rozek Elizabeth	CA	O	Chief Le	3	S	-194	8.12	-24		224	D
7/22/26 16:05	7/20/26	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	Kooij Louise Frederika		O	Chief Ac	10	S.dm	-21,283	31.35	-679		24	D
7/22/26 16:05	7/20/26	SGMT	Sagimet Biosciences Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kemble George	CA	D		2	S	-431	7.62	-57		81	D
7/21/26 20:50	7/20/26	AKTS	Aktis Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Herrmann Ken	MA	D		2	S.d	-197	24.81	-8	-100	0	D
7/21/26 19:24	3/27/26	RANI	Rani Therapeutics Holdings, Inc.	CA	Health	Drug	Pharmaceutical Preparations	Javadi Alireza	CA	O	Chief Te	1	S	0	0.7798	0		9	D
7/21/26 18:25	12/27/24	RANI	Rani Therapeutics Holdings, Inc.	CA	Health	Drug	Pharmaceutical Preparations	Imran Talat	CA	DO	CEO	1	S	-11	1.41	-8		435	D
7/21/26 17:27	7/20/26	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	Broadhurst Vanessa	NJ	O	EVP,Glob	2	S.d	-7,301	249.60	-29		23	D
7/21/26 17:24	7/17/26	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hohl Benjamin	CA	O	CFO	13	S.d	-1,439	28.91	-50		51	D
7/21/26 17:23	7/17/26	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Collins Helen Louise	CA	O	CHIEF ME	7	S.d	-3,640	33.09	-110		25	D
7/21/26 16:15	7/20/26	IMNN	Imunon, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Eylward Susan	NJ	O	GC,Corp	3	S	-26	1.76	-15		3	D
7/20/26 21:16	7/20/26	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sibold William John	PA	DO	P,CEO	6	S.d	-10,535	457.37	-23		209	D
7/20/26 21:00	7/13/26	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rodman David Malcom	PA	O	Chief Me	28	S.dm	-16,461	29.23	-563		117	D
7/20/26 14:55	7/17/26	LYEL	Lyell Immunopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Innovative Cellular Therapeutics Holdings Ltd		T		2	S	0	13.70	0	0	2,857	D
7/20/26 06:00	7/15/26	MPLT	Maplight Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gillis Jonathan	CA	O	CAO,Inte	3	S.m	-3,556	32.21	-110		251	D
7/20/26 06:00	7/15/26	MPLT	Maplight Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kreitzer Anatol	CA	O	Chief Di	3	S.m	-2,781	32.71	-85		257	D
7/17/26 21:46	7/15/26	MPLT	Maplight Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kroeger Christopher A.	CA	DO	CEO	5	S.m	-12,542	31.10	-403		1,732	D
7/17/26 21:45	7/15/26	MPLT	Maplight Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lillie James Woodruff	CA	O	Chief Sc	4	S.m	-2,285	30.38	-75		295	D
7/17/26 21:44	7/15/26	MPLT	Maplight Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hanson Kristopher	CA	O	GC	4	S.m	-1,464	31.72	-46		190	D
7/17/26 21:43	7/17/26	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	Thomson David	CT	O	EVP Genl	6	S.d	-1,121	5.17	-217		891	D
7/17/26 21:43	7/15/26	MPLT	Maplight Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Foff Erin Pennock	CA	O	Chief Me	4	S.m	-3,376	32.12	-105		401	D
7/17/26 21:42	7/17/26	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	Binder Steven B.	CT	D		6	S.d	-1,251	4.16	-301		1,007	D
7/17/26 19:12	6/9/25	ETON	Eton Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T		13	S.m	-18,135	38.03	-477		6,693	I
7/17/26 19:00	7/15/26	SEPN	Septerna, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bhatt Elizabeth	CA	O	P,COO	3	S.d	-349	29.10	-12		174	D
7/17/26 18:38	7/15/26	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Wilson James N	CA	D		2	S	-1,715	85.75	-20		1,495	I
7/17/26 18:31	7/15/26	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Mokari Atabak	CA	O	CFO	3	S.d	-9,554	79.62	-120		16	D
7/17/26 17:09	7/16/26	SDGR	Schrodinger, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jain Rachit	NY	O	EVP,CFO	3	S	-45	13.56	-3		53	D
7/17/26 16:09	8/21/25	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Raab Michael	MA	DO	P,CEO	13	S.d	-3,177	5.54	-573		1,882	D
7/17/26 16:05	7/15/26	PVLA	Palvella Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Goin Kathleen	PA	O	COO	9	S.d	-4,197	108.39	-39	-100	0	D
7/17/26 16:01	5/1/26	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Welgus Howard G.	CA	D		16	S.dm	-3,047	20.88	-146		122	D
7/17/26 13:15	7/15/26	AQST	Aquestive Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Barber Daniel	NJ	DO	P,CEO	6	S.dm	-1,547	4.68	-331		1,015	D
7/16/26 17:39	7/14/26	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Jamil Khurram	GA	O	Chief Me	8	S.dm	-1,436	5.04	-285		4	D
7/16/26 16:30	8/21/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	34	S.d	-142,113	422.70	-336		45	D
7/15/26 20:58	7/13/26	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Congleton Jon	PA	DO	CEO	9	S	-15,324	34.91	-439		862	D
7/15/26 19:36	7/15/26	ORKA	Oruka Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Goncalves Joana	CA	O	Chief Me	8	S.d	-3,026	52.55	-58		34	D
7/15/26 15:36	7/13/26	SHPH	Shuttle Pharmaceuticals Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hrt Financial LP	NY	T		16	S.m	-1,028	0.0772	-13,318		3,043	D
7/15/26 13:08	7/13/26	PHVS	Pharvaris N.V.	P7	Health	Drug	Pharmaceutical Preparations	Modig Berndt	MA	DO	CEO	5	S	-931	28.65	-33		1,092	D
7/14/26 20:11	7/13/26	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Krepp Sarah	NC	O	Chief Hu	11	S.d	-3,713	51.51	-72		165	D
7/14/26 20:09	7/13/26	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Khindri Sanjeev	NC	O	Chief De	2	S	-355	66.81	-5		67	D
7/14/26 20:08	7/13/26	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Kaseta Michael	NC	O	CFO,COO	15	S.dm	-17,671	37.05	-477		412	D
7/14/26 20:07	9/2/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Jeffs Roger	NC	DO	CEO	21	S.dm	-46,529	54.69	-851		2,836	D
7/14/26 20:04	7/13/26	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Schundler Russell	NC	O	GC	11	S.d	-3,234	35.96	-90		629	D
7/14/26 20:02	7/13/26	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Saggar Rajeev	NC	O	Chief Me	12	S.d	-6,073	31.31	-194		273	D
7/14/26 20:01	7/13/26	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Moomaw Scott	NC	O	Chief Co	13	S.d	-7,782	33.60	-232		225	D
7/14/26 18:32	7/13/26	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Quisel John D	MA	DO	CEO	6	S.d	-11,629	72.56	-160		226	D
7/14/26 16:22	11/24/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mazumdar Claire	MA	DO	CEO	9	S.dm	-3,777	19.88	-190		362	D
7/14/26 16:02	7/13/26	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Cook Meredith	NJ	O	SVP,GC,S	15	S	-526	78.46	-7		80	D
7/13/26 17:36	6/22/26	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jaen Juan C.	CA	O	P	8	S.m	-9,219	23.81	-387		1,459	I
7/13/26 17:09	7/13/26	ORKA	Oruka Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Agarwal Arjun	CA	O	SVP,Fina	5	S.dm	-2,286	71.15	-32		19	D
7/13/26 17:00	7/9/26	DNTH	Dianthus Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	Savitz Ryan	NY	O	EVP,CFO,	5	S.d	-14,992	77.34	-194	-100	0	D
7/13/26 16:41	7/9/26	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ellis Andrea	CA	D		5	S.d	-7,866	56.49	-139		23	D
7/13/26 16:40	7/9/26	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cook Jennifer E.	CA	D		3	S.dm	-21,920	78.80	-278		8	D
7/13/26 16:31	7/10/26	INDV	Indivior Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Heidbreder Christian	VA	O	Chief Sc	2	S	-1,472	39.60	-37		228	D
7/13/26 16:10	7/9/26	MLTX	Moonlake Immunotherapeutics	E9	Health	Drug	Pharmaceutical Preparations	Santos Da Silva Jorge		DO	CEO	4	S.m	-8,730	17.46	-500		2,925	D
7/13/26 16:03	7/10/26	RDHL	Redhill Biopharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Raday Gilead		O	COO	2	S.d	-3	0.0001	-29,870		261,060	D
7/13/26 16:00	7/9/26	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mazzariello Gina	MA	O	GC	7	S.m	-1,144	12.47	-92		188	D
7/10/26 18:15	7/8/26	ANTX	An2 Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Eizen Joshua M	CA	O	See Rema	3	S.m	-53	1.58	-34		207	D
7/10/26 17:20	7/8/26	CTNM	Contineum Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lorrain Daniel S.	CA	O	Chief Sc	12	S.dm	-1,134	14.92	-76		171	D
7/10/26 16:30	7/9/26	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pelish Henry E.	MA	O	Chief Sc	11	S.dm	-8,901	91.18	-98		83	D
7/10/26 16:10	12/15/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cohlhepp Ryan	MA	DO	P,COO	12	S.dm	-3,671	20.48	-179		214	D
7/10/26 16:10	12/22/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hyep Ivan	MA	O	CFO	10	S.dm	-2,892	20.90	-138		145	D
7/10/26 16:02	7/10/26	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Malcolm Jan	MD	D		9	S.d	-628	458.51	-1		1	D
7/10/26 14:17	7/9/26	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Schoenberg Mark	NJ	O	Chief Me	10	S.d	-1,918	26.00	-74		158	D
7/10/26 06:11	7/8/26	AKTS	Aktis Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ron-Bigger Shulamit	MA	O	COO	1	S.d	-1,388	27.75	-50	-100	0	D
7/10/26 06:10	7/8/26	AKTS	Aktis Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Czibere Akos	MA	O	Chief Me	1	S.d	-1,389	27.77	-50	-100	0	D
7/9/26 19:35	7/7/26	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yu Jonathan Yen-Wen	MA	O	COO	6	S.d	-4,767	76.95	-62		54	D
7/9/26 19:26	7/7/26	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	EVP,Chie	8	S.dm	-19,804	76.03	-260		100	M
7/9/26 19:22	7/9/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Seshadri Vishwas	OH	DO	CEO	10	S.m	-2,517	5.74	-439		1,460	D
7/9/26 19:20	7/9/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	O'Malley Brendan M.	OH	O	SVP,GC	7	S.m	-443	5.93	-75		451	D
7/9/26 19:17	7/9/26	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Vasanthavada Madhav	OH	O	Chief Co	4	S.m	-239	5.92	-40		319	D
7/9/26 18:07	7/7/26	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Diaz Allene M.	CA	D		3	S.d	-5,279	79.48	-66		18	D
7/9/26 18:07	7/7/26	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Kordasiewicz Holly B.	CA	O	EVP,Chie	3	S.d	-4,810	73.61	-65		22	D
7/9/26 17:38	7/7/26	IMNM	Immunome Inc.	DE	Health	Drug	Pharmaceutical Preparations	Horn Kinney	WA	O	CHIEF BU	1	S.d	-27	25.00	-1	-100	0	D
7/9/26 17:30	7/7/26	ATAI	Ataibeckley Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hershberg Robert	NY	D		1	S.d	-496	4.96	-100		100	D
7/9/26 16:56	7/7/26	IDYA	Ideaya Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ruiz Briseno Andres	CA	O	Chief Ac	1	S.d	-382	40.01	-10		26	D
7/9/26 16:54	7/8/26	SNDX	Syndax Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Metzger Michael A	NY	DO	CEO	6	S.d	-4,080	17.85	-229		509	D
7/9/26 16:47	7/7/26	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Thompson Peter A.	MA	D		11	S.dm	-60,567	25.12	-2,411		10,762	I
7/9/26 16:45	7/7/26	VERA	Vera Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fordyce Marshall	CA	DO	P,CEO	5	S	-5,059	41.09	-123		479	D
7/9/26 16:44	7/7/26	PMVP	Pmv Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T		18	S.dm	-118,487	22.72	-5,216		25,237	I
7/9/26 16:32	7/7/26	IRWD	Ironwood Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Silver Ronald	MA	O	PFO,PAO	4	S.m	-834	4.38	-190		314	D
7/8/26 20:21	7/6/26	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Auerbach Alan H	CA	DOT	P,CEO	3	S.m	-736	5.83	-126		7,262	D
7/8/26 20:19	7/6/26	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hunt Douglas M	CA	O	See Rema	3	S.m	-150	5.95	-25		197	D
7/8/26 20:18	7/6/26	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Nougues Maximo F	CA	O	CFO	3	S.m	-175	5.88	-30		231	D
7/8/26 19:54	7/7/26	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Guyer William	CA	O	Chief De	22	S.dm	-21,740	66.08	-329		5	D
7/8/26 18:49	7/8/26	CTNM	Contineum Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Stengone Carmine N.	CA	DO	CEO,P	4	S.dm	-320	16.01	-20		17	D
7/8/26 17:35	7/6/26	DYN	Dyne Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rhodes Jason P	MA	D		7	S.m	-63,911	20.60	-3,103		1,286	I
7/8/26 17:34	3/27/25	HOWL	Werewolf Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Evnin Luke	MA	D		32	S.dm	-3,258	0.7555	-4,312		4,310	I
7/8/26 17:15	7/6/26	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kunkel Lori Anne	CA	D		2	S	-850	42.51	-20		52	D
7/8/26 17:12	7/6/26	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Peetz Christopher	CA	DO	CEO	9	S.d	-17,247	77.93	-221		382	D
7/8/26 17:07	9/12/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bjerkholt Eric	CA	O	CFO	7	S.d	-2,713	72.65	-37		50	D
7/8/26 16:40	7/6/26	ALMS	Alumis Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pangali Sanam	CA	O	GC	1	S.d	-140	28.00	-5		11	D
7/8/26 16:30	7/6/26	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Porter James Richard	MA	DO	P,CEO	14	S.dm	-34,876	88.64	-393		325	D
7/8/26 16:13	7/6/26	TBPH	Theravance Biopharma, Inc.	CA	Health	Drug	Pharmaceutical Preparations	Samaha Eli	NY	T		2	S.m	-5,911	17.20	-344		9,174	I
7/8/26 16:03	7/6/26	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Flammer Martina M.D.	NJ	O	Chief Me	17	S.dm	-53,417	136.07	-393		95	D
7/7/26 21:08	7/6/26	NGNE	Neurogene Inc.		Health	Drug	Pharmaceutical Preparations	Cvijic Christine Mikail	NY	DO	P,CFO	7	S.m	-976	27.81	-35		110	D
7/7/26 20:00	7/6/26	DMRA	Damora Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Winslow Garrett	MA	O	GC	3	S.d	-14	18.00	-1		2	D
7/7/26 19:50	7/6/26	NBP	Novabridge Biosciences	E9	Health	Drug	Pharmaceutical Preparations	Xu Cong Claire	MD	O	SVP,Clin	2	S.d	-18	2.23	-8		298	D
7/7/26 19:02	7/6/26	IMNM	Immunome Inc.	DE	Health	Drug	Pharmaceutical Preparations	Barchas Isaac	WA	D		3	S.m	-15,136	22.12	-684		4,166	I
7/7/26 19:00	7/2/26	STTK	Shattuck Labs, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Shukla Abhinav A.	TX	O	Chief Te	3	S.dm	-183	7.07	-26		99	D
7/7/26 18:04	7/2/26	KRRO	Korro Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Formela Jean Francois	MA	D		3	S.m	-4,041	14.22	-284		195	I
7/7/26 17:42	7/2/26	IMNM	Immunome Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lechleider Robert	WA	O	Chief Me	2	S.d	-2,336	21.24	-110		16	D
7/7/26 17:11	7/6/26	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	Pieper Steven	IL	O	See Rema	1	S.m	-383	8.52	-45		1,366	D
7/7/26 17:00	7/2/26	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Perry Jennifer Scott		O	COO	2	S.m	-13	4.62	-3		92	D
7/7/26 17:00	7/2/26	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Skynner Michael		O	CHIEF SC	6	S.dm	-106	6.43	-17		162	D
7/7/26 17:00	7/2/26	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Lee Kevin		DO	CEO	6	S.dm	-341	6.41	-53		619	D
7/7/26 17:00	7/2/26	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Hannay Michael Charles Ferguson		O	CHIEF PR	6	S.dm	-68	6.21	-11		98	D
7/7/26 17:00	7/2/26	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Thompson Travis Alvin		O	CFO	6	S.dm	-32	6.14	-5		66	D
7/7/26 16:47	7/2/26	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Kapusta Matthew C		DO	CEO,MD	7	S.dm	-22,247	40.43	-550		661	D
7/7/26 16:38	7/6/26	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fitzpatrick Jennifer	MA	O	GC	4	S.d	-1,446	35.27	-41	-100	0	D
7/7/26 16:30	7/2/26	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Vivaldi Coelho Rogerio	CA	D		2	S	-301	37.60	-8		19	D
7/7/26 16:15	7/2/26	VRTX	Vertex Pharmaceuticals Inc / Ma	MA	Health	Drug	Pharmaceutical Preparations	Tatsis Ourania	MA	O	EVP,Chie	7	S.m	-6,513	475.32	-14		51	D
7/7/26 16:08	7/2/26	VRTX	Vertex Pharmaceuticals Inc / Ma	MA	Health	Drug	Pharmaceutical Preparations	McKechnie Duncan	MA	O	EVP,Chie	4	S	-5,665	491.69	-12		18	D
7/7/26 16:05	7/2/26	REGN	Regeneron Pharmaceuticals, Inc.	NY	Health	Drug	Pharmaceutical Preparations	Ryan Arthur F	NY	D		5	S	-435	724.47	-1		18	D
7/6/26 18:49	7/1/26	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Klein Joseph III	CA	D		7	S.d	-9,356	70.20	-133		16	D
7/6/26 18:23	9/2/25	JAZZ	Jazz Pharmaceuticals Plc	L2	Health	Drug	Pharmaceutical Preparations	Cozadd Bruce C		D		14	S.dm	-25,592	178.97	-143		440	D
7/6/26 17:44	7/1/26	BOLD	Boundless Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Crandell Keith	IL	T		1	S.d	-40	2.49	-16		2,694	I
7/6/26 17:43	7/1/26	BOLD	Boundless Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Arch Venture Fund Ix, L.P.	IL	T		1	S.d	-40	2.49	-16		2,694	I
7/6/26 17:11	7/1/26	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Reardon Andrew	FL	O	CLO,Secr	8	S.d	-6,115	226.47	-27		42	D
7/6/26 16:48	7/6/26	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	Gaffin David Joseph	MA	O	EVP,CLO,	5	S.dm	-455	37.32	-12		236	D
7/6/26 16:44	7/1/26	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Maduck Sean	CA	O	See Rema	14	S.dm	-32,453	79.80	-407		119	D
7/6/26 16:31	7/1/26	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Noci Darlene	MA	O	Chief De	19	S.dm	-12,895	104.48	-123		58	D
7/6/26 16:30	7/1/26	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Balcom Alexandra	MA	O	CFO	14	S.dm	-21,897	93.04	-235		99	D
7/6/26 16:30	7/1/26	ALXO	Alx Oncology Holdings Inc	DE	Health	Drug	Pharmaceutical Preparations	Wong Shelly	CA	O	SVP,FINA	7	S	-12	1.13	-11		89	D
7/6/26 16:13	7/1/26	VRTX	Vertex Pharmaceuticals Inc / Ma	MA	Health	Drug	Pharmaceutical Preparations	Liu Joy	MA	O	EVP,GC	5	S	-2,131	460.34	-5		23	D
7/6/26 16:10	7/1/26	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ticho Barry	MA	O	Chief Me	16	S.dm	-2,130	19.82	-107		61	D
7/6/26 15:37	6/1/26	RARE	Ultragenyx Pharmaceutical Inc.	DE	Health	Drug	Pharmaceutical Preparations	Horn Howard	CA	O	CFO	9	S.m	-1,215	26.42	-46		110	D
7/2/26 21:33	6/25/26	SYRE	Spyre Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Burrows Scott L	MA	O	CFO	7	S.d	-4,161	58.67	-71		98	D
7/2/26 21:33	5/1/26	SYRE	Spyre Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sloan Sheldon	MA	O	Chief Me	4	S.d	-7,354	71.43	-103	-100	0	D
7/2/26 21:32	5/1/26	SYRE	Spyre Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Turtle Cameron	MA	DO	CEO	9	S	-7,252	43.95	-165		702	D
7/2/26 20:15	6/30/26	STTK	Shattuck Labs, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pandite Arundathy N.	TX	O	Chief Me	2	S	-409	6.81	-60		166	D
7/2/26 19:23	7/1/26	TNGX	Tango Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Crystal Adam	MA	O	P,R,D	9	S.d	-4,989	19.84	-252		187	D
7/2/26 19:06	6/30/26	NKTR	Nektar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	Zalevsky Jonathan	CA	O	Chief R,	10	S.d	-1,060	35.01	-30		306	D
7/2/26 19:03	6/30/26	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Fitzgerald Meghan		D		2	S.d	-2,271	28.38	-80		43	D
7/2/26 19:00	7/1/26	SEPN	Septerna, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Long Daniel D.	CA	O	SVP,Drug	3	S.d	-710	32.53	-22		96	D
7/2/26 18:01	7/1/26	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Howe Jolanda	CA	O	SVP,GLOB	10	S.dm	-4,586	54.70	-84		8	D
7/2/26 17:21	7/1/26	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Russell Alan J	CO	DO	Chief Sc	5	S.d	-11,505	28.52	-403		25	D
7/2/26 17:17	7/1/26	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Lee Sung	CA	O	EVP,CFO	5	S.d	-5,696	79.31	-72		87	D
7/2/26 17:00	7/1/26	ORMP	Oramed Pharmaceuticals Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hexter Joshua	NY	O	COO,CBO	1	S.d	-611	4.46	-137		1,073	D
7/2/26 17:00	7/1/26	ORMP	Oramed Pharmaceuticals Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gabay Avraham	NY	O	CFO	1	S	-331	4.51	-73		672	D
7/2/26 16:59	6/30/26	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Abi-Saab Walid		O	Chief Me	6	S.d	-2,632	32.74	-80		190	D
7/2/26 16:54	6/30/26	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Kaye Jack		D		7	S.d	-2,724	34.74	-78		26	D
7/2/26 16:40	7/1/26	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	McCulloch Kevin	IL	O	See Rema	2	S	-843	8.02	-105		1,716	D
7/2/26 16:38	3/20/25	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	Hecht Beth	IL	O	See Rema	10	S.d	-1,248	6.57	-190		1,354	D
7/2/26 16:35	7/1/26	GNLX	Genelux Corp	DE	Health	Drug	Pharmaceutical Preparations	Smither John W	CA	D		1	S	-35	2.91	-12		91	D
7/2/26 16:30	6/30/26	PYXS	Pyxis Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dupont Jakob	MA	D		1	S.d	-107	3.06	-35		39	D
7/2/26 16:30	6/30/26	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Alland Leila	OH	D		2	S	-157	5.40	-29		174	D
7/2/26 16:10	7/1/26	RPRX	Royalty Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Urist Marshall	NY	O	EVP,Rese	14	S	-12,069	41.80	-289		228	D
7/2/26 16:08	6/30/26	RPRX	Royalty Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Hite Christopher	NY	O	EVP,CB,P	2	S	-15,505	55.37	-280		629	M
7/2/26 16:05	6/30/26	LEGN	Legend Biotech Corp	E9	Health	Drug	Pharmaceutical Preparations	Casey Patrick John	NJ	D		1	S	-89	14.80	-6		49	D
7/2/26 16:03	10/30/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gheuens Sarah	MA	O	Chief Me	10	S.d	-1,401	36.09	-39		85	D
7/2/26 12:57	7/1/26	EBS	Emergent Biosolutions Inc.	DE	Health	Drug	Pharmaceutical Preparations	Williams Paul Anthony	MD	O	SVP,Prod	2	S	-59	8.42	-7		159	D
7/1/26 21:52	6/29/26	CVKD	Cadrenal Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pham Quang X	FL	DOT	CB,CEO	16	S.m	-701	5.85	-120		413	D
7/1/26 21:30	7/1/26	ORKA	Oruka Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fairmount Funds Management LLC	PA	DT		4	S.d	-1,069,693	57.09	-18,738		10,021	I
7/1/26 19:58	7/1/26	ORKA	Oruka Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sandler Laura Lee	CA	O	COO	6	S.d	-1,397	47.83	-29		238	D
7/1/26 19:30	7/1/26	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tabuteau Herriot	NY	DOT	CEO	8	S.dm	-100,044	160.50	-623		7,352	D
7/1/26 19:06	6/29/26	PHVS	Pharvaris N.V.	P7	Health	Drug	Pharmaceutical Preparations	Schikan Johannes Gerardus Christiaan Petrus	MA	D		4	S.m	-2,626	32.82	-80		388	D
7/1/26 19:04	6/30/26	CTNM	Contineum Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Watkins Tim	CA	O	CMO,Head	4	S.d	-323	14.89	-22		9	D
7/1/26 19:02	6/29/26	PHVS	Pharvaris N.V.	P7	Health	Drug	Pharmaceutical Preparations	Lesage Anne	MA	O	Chief Ea	4	S.dm	-4,759	33.10	-144		213	M
7/1/26 18:34	6/29/26	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Epperly Melissa B,		D		1	S.d	-610	34.38	-18		16	D
7/1/26 18:29	7/1/26	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	Hopkinson Craig C.	MA	O	EVP R,D,	12	S.d	-3,081	34.71	-89		89	D
7/1/26 18:21	6/29/26	PGEN	Precigen, Inc.	VA	Health	Drug	Pharmaceutical Preparations	Shah Rutul R	MD	O	COO	2	S.d	-437	5.11	-86		498	D
7/1/26 18:19	6/29/26	PGEN	Precigen, Inc.	VA	Health	Drug	Pharmaceutical Preparations	Sabzevari Helen	MD	O	P,CEO	2	S.d	-2,563	5.50	-466		3,769	D
7/1/26 16:34	6/29/26	AKBA	Akebia Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ostrowski Erik	MA	O	SVP,CFO,	3	S	-262	1.98	-132		673	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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