Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	Title	#f	T	TVal	Price	Qty	oc	Own	H
6/30/25 17:51	6/26/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Valantine Hannah	CA	D		4	S.d	-909	36.65	-25		8	M
6/30/25 17:02	6/26/25	ZVRA	Zevra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Thompson Rahsaan	FL	OH	Chief Le	1	S	-221	9.21	-24		43	D
6/27/25 17:07	6/26/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Noci Darlene	MA	O	Chief De	12	S.dm	-7,642	77.18	-99		48	D
6/27/25 17:05	6/25/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pelish Henry E.	MA	O	Chief Sc	5	S.dm	-5,214	91.83	-57		66	D
6/27/25 16:39	6/26/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	13	S.d	-33,985	291.97	-116		37	D
6/27/25 16:27	6/27/25	NATR	Natures Sunshine Products Inc	UT	Health	Drug	Pharmaceutical Preparations	Shanghai Fosun Pharmaceutical (Group) Co., Ltd.	F4	T		3	S.m	-32,889	11.47	-2,868		2,921	I
6/27/25 16:15	6/26/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Edmondson Frazor Titus III	MA	O	GC	10	S.d	-1,468	26.32	-56		39	D
6/27/25 16:15	6/25/25	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	Lee Ting-Chuan	CA	D		1	S	-1	0.5100	-3	0	1,429	D
6/27/25 16:15	6/25/25	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	Tsai Chun-Jung	CA	D		2	S.m	-22	0.5166	-43		1,402	D
6/27/25 16:15	6/26/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Du Ying	MA	DO	Chairper	10	S.dm	-14,160	30.65	-462		1,143	D
6/27/25 16:15	6/26/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Chen Yajing	MA	O	CFO	10	S.d	-685	29.91	-23		27	D
6/26/25 20:00	6/24/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Shelton Jerrell	TN	DO	P,CEO	9	S.dm	-4,936	7.55	-654		937	D
6/26/25 20:00	6/24/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kharabi Darius	MA	O	CHIEF BU	5	S.d	-62	4.91	-13		68	D
6/26/25 20:00	6/24/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Mandalam Ramkumar	TN	D		6	S.dm	-344	7.75	-44		77	D
6/26/25 20:00	6/24/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Reumuth Mary	MA	O	CFO	5	S.d	-69	4.87	-14		69	D
6/26/25 20:00	6/24/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bazemore Todd	MA	O	SEE REMA	5	S.d	-79	4.88	-16		88	D
6/26/25 20:00	6/24/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Brazzell Romulus K	MA	O	SEE REMA	5	S.d	-92	4.86	-19		92	D
6/26/25 20:00	6/24/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Iwicki Mark T	MA	D		6	S.d	-295	4.67	-63		280	D
6/26/25 17:26	6/24/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Burns James William	MA	O	GC	5	S.d	-1,472	46.36	-32		37	D
6/26/25 17:25	6/24/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gheuens Sarah	MA	O	Chief Me	5	S.d	-505	36.29	-14		57	D
6/26/25 17:24	6/24/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jones Cecilia	MA	O	CFO	4	S.d	-287	39.49	-7		30	D
6/26/25 17:23	6/24/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Milanova Tsveta	MA	O	Chief Co	3	S.d	-243	33.48	-7		26	D
6/26/25 17:22	6/24/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Goff Brian	MA	DO	CEO	5	S.d	-2,289	38.78	-59		112	D
6/26/25 17:08	6/24/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McCormick Frank	CA	D		1	S	-4,423	44.23	-100		963	I
6/25/25 19:44	6/25/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Weinhoff Gregory M	X0	O	Chief Bu	13	S.dm	-2,999	15.12	-198		223	D
6/25/25 19:43	6/24/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Hussain Iqbal J	X0	O	GC	7	S.dm	-1,813	15.95	-114		131	D
6/25/25 19:42	6/24/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Accardi Mario Alberto	X0	O	P,Orexin	1	S.d	-210	14.00	-15		216	D
6/25/25 18:52	6/23/25	OKUR	Onkure Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Saccomano Nicholas A	CO	DO	P,CEO	2	S.m	-3	2.89	-1		4	D
6/25/25 18:49	6/23/25	OKUR	Onkure Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Leverone Jason A.	CO	O	CFO	2	S.m	-10	2.89	-3		13	D
6/25/25 17:09	6/23/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Wang Lai	V8	O	Global H	7	S.m	-3,979	227.60	-17		1,797	D
6/25/25 17:08	6/23/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Wu Xiaobin	V8	O	P,COO	13	S.dm	-44,882	254.28	-177		1,262	D
6/25/25 17:08	6/24/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Wang Xiaodong	V8	DH	Chair, S	10	S.d	-77,751	221.62	-351		10,325	D
6/25/25 17:06	6/23/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Oyler John	V8	DO	CEO	12	S.dm	-83,394	222.62	-375		54,270	D
6/25/25 17:01	6/23/25	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	Taiwan Carbon Nano Technology Corp	F5	T		1	S	0	0.00	-29		5,471	D
6/25/25 16:38	6/24/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mesa Nilda	MD	D		5	S	-532	310.29	-2		6	D
6/25/25 16:36	6/24/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Giltner Richard	MD	D		2	S.d	-4,696	360.25	-13		19	D
6/25/25 16:18	6/23/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Bonstein Sara	NJ	O	CFO	10	S.dm	-29,820	66.12	-451		156	D
6/24/25 21:01	6/20/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Venker Eric	NY	O	P,COO	12	S.dm	-36,949	11.06	-3,340		1,462	D
6/24/25 20:29	6/23/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Reardon Andrew	FL	O	CLO,Secr	6	S.d	-1,408	90.81	-16		33	D
6/24/25 18:33	6/23/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Piscitelli Dominic	CA	O	CFO	5	S.dm	-490	10.02	-49		107	D
6/24/25 18:08	6/20/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Springhorn Jeremy P.	P7	D		2	S	-42	9.66	-4		38	D
6/24/25 18:03	6/20/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Post Leonard E	P7	D		2	S	-42	9.68	-4		30	D
6/24/25 17:53	6/20/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Kaye Jack	P7	D		2	S	-42	9.69	-4		20	D
6/24/25 17:50	6/20/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Jacques Rachelle Suzanne	P7	D		2	S	-42	9.68	-4		28	D
6/24/25 17:45	6/20/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Gut Robert	P7	D		2	S	-66	9.67	-7		57	D
6/24/25 17:42	6/20/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Balachandran Madhavan	P7	D		2	S	-42	9.66	-4		38	D
6/24/25 17:36	6/20/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lyssikatos Joseph P	CO	O	CHIEF SC	19	S.dm	-5,344	23.25	-230		1,117	I
6/24/25 17:34	6/20/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Meek David D.	P7	D		2	S	-42	9.66	-4		34	D
6/24/25 16:39	6/20/25	VSTM	Verastem, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Paterson Dan	MA	DO	P,CEO	14	S.m	-647	6.95	-93		462	D
6/24/25 16:37	6/20/25	VSTM	Verastem, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Calkins Daniel	MA	O	CFO	13	S.m	-114	7.26	-16		114	D
6/24/25 16:08	6/24/25	ARVN	Arvinas, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Saik Andrew	CT	O	CFO	1	S	-43	7.61	-6		164	D
6/24/25 16:00	6/20/25	MRUS	Merus N.V.	P7	Health	Drug	Pharmaceutical Preparations	Silverman Peter B.	P7	O	COO,GC	3	S.d	-5,898	55.64	-106	-100	0	D
6/23/25 19:42	6/20/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Murdock Hunter R.	NY	O	GC	2	S.dm	-3,647	101.28	-36	-100	0	D
6/23/25 16:10	6/20/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Lis William	MA	D		3	S	-1,168	29.78	-39		53	D
6/23/25 13:50	6/20/25	RARE	Ultragenyx Pharmaceutical Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sanders Corazon (Corsee) D.	CA	D		3	S	-185	39.20	-5		15	D
6/23/25 11:35	6/18/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Ramaswamy Vivek	DC	T		3	S.m	-31,669	11.35	-2,789		52,532	D
6/20/25 21:09	6/18/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cheng Andrew	CA	DO	P,CEO	16	S.dm	-19,375	37.57	-516		716	D
6/20/25 21:08	6/18/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gangloff Scott A.	CA	O	CTO	1	S	-47	54.84	-1		23	D
6/20/25 21:08	6/20/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lamy Patrick	CA	O	SVP,Comm	11	S.d	-1,351	47.74	-28		34	D
6/20/25 21:07	6/18/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rolph Timothy	CA	O	Chief Sc	15	S.dm	-6,992	49.54	-141		198	D
6/20/25 21:07	6/18/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	White William Richard	CA	O	CFO	19	S.dm	-9,312	28.77	-324		62	D
6/20/25 21:07	6/18/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yale Catriona	CA	O	Chief De	24	S.dm	-12,115	42.90	-282		96	D
6/20/25 21:06	6/18/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Young Jonathan	CA	O	COO	20	S.d	-7,584	34.24	-222		587	D
6/20/25 20:58	6/20/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Saha Saurabh	X0	DO	CEO	16	S.dm	-14,266	15.76	-905		862	D
6/20/25 20:24	6/16/25	IGMS	Igm Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Weber Steven	CA	O	Principa	8	S.m	-30	3.89	-8		32	D
6/20/25 20:23	6/16/25	IGMS	Igm Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tahir Misbah	CA	O	CFO	6	S.m	-107	5.62	-19		188	D
6/20/25 20:20	6/16/25	IGMS	Igm Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Harler Mary Beth	CA	DO	CEO	5	S	-53	3.87	-14		347	D
6/20/25 20:19	6/16/25	IGMS	Igm Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Decker Lisa Lynn	CA	O	Chief Bu	6	S.m	-67	5.64	-12		79	D
6/20/25 19:43	6/16/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Potts Jeannette		O	GC	3	S.d	-167	10.12	-17		120	D
6/20/25 18:38	6/18/25	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Karas Eric	CA	O	Chief Co	5	S.dm	-800	14.55	-55		8	D
6/20/25 17:42	6/17/25	TYRA	Tyra Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kaplan Gilla	CA	D		2	S.m	-628	10.23	-61		38	D
6/20/25 16:32	6/18/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Welgus Howard G.	CA	D		13	S.d	-1,521	11.69	-130		205	D
6/20/25 16:20	6/20/24	CLYM	Climb Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pimblett Emily	MA	O	SVP,Fina	5	S.d	-24	3.98	-6		19	D
6/20/25 16:08	6/13/24	NKTX	Nkarta, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hastings Paul J	CA	DO	CEO	4	S.d	-76	3.50	-22		333	D
6/20/25 16:07	6/18/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Fenton Dennis M	CA	D		2	S	-117	23.66	-5		5	D
6/20/25 16:06	6/18/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Renton Hollings	CA	D		4	S.d	-674	26.99	-25		5	D
6/20/25 11:22	6/16/25	VSTM	Verastem, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gagnon Robert E.	MA	D		7	S.dm	-12	5.56	-2		42	D
6/20/25 11:21	6/13/25	VSTM	Verastem, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Stuglik Brian M	MA	D		9	S.dm	-87	3.82	-23		197	D
6/18/25 18:45	6/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Looker Benjamin	MI	O	GC	1	S	-7	1.15	-6		401	D
6/18/25 18:44	6/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Koenig Sheldon L.	MI	DO	P,CEO	4	S	-110	1.56	-71		1,572	D
6/18/25 18:44	6/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Halladay Benjamin	MI	O	CFO	6	S	-21	1.53	-14		482	D
6/18/25 18:26	6/16/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Robb Gary Charles	CA	O	Chief Bu	8	S.d	-2,412	43.72	-55		52	D
6/18/25 18:22	6/17/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kintz Samuel	CO	DO	P,CEO	18	S.dm	-5,080	23.27	-218		1,265	I
6/18/25 18:04	6/17/25	ARVN	Arvinas, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cacace Angela M	CT	O	Chief Sc	2	S	-90	13.19	-7		154	D
6/18/25 18:02	6/17/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gallagher Kathleen P.	CA	O	Chief Pr	7	S.dm	-1,212	30.53	-40		51	D
6/18/25 17:18	6/16/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Franchi Jean M.	MA	O	CFO	2	S	-276	53.68	-5		70	D
6/18/25 17:12	6/16/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Meisner Lara	MA	O	GC	2	S.d	-1,186	12.49	-95	-100	0	D
6/18/25 17:12	6/16/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Lee Chan Henry	V8	O	SVP,GC	7	S	-1,422	236.87	-6		278	D
6/18/25 16:50	6/16/25	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	Kling Douglas F	P7	O	COO	8	S.dm	-1,929	2.69	-717		44	D
6/18/25 16:39	6/16/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Tessari Eben	X0	O	COO	13	S.dm	-6,222	25.32	-246		123	D
6/18/25 16:31	6/16/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Fisher Andrew	X0	O	GC	3	S.d	-1,842	9.90	-186		360	D
6/18/25 16:16	6/16/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Lewis William	NJ	DO	Chair,CE	18	S.dm	-43,373	78.67	-551		738	M
6/18/25 16:15	6/16/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Adsett Roger	NJ	O	COO	9	S.dm	-9,946	73.61	-135		189	D
6/18/25 16:15	6/16/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bredt David	MA	O	Chief Sc	4	S	-348	10.24	-34		469	D
6/18/25 16:11	6/16/25	AMRX	Amneal Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Patel Gautam	NJ	D		8	S.m	-3,951	8.23	-480		2,031	D
6/18/25 08:49	6/16/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Watson David O.	MA	O	GC	7	S	-735	27.47	-27		228	D
6/17/25 19:55	6/13/25	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Wilson Troy Edward	CA	D		2	S	-127	3.35	-38		44	D
6/17/25 19:49	6/13/25	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Senderowicz Adrian	CA	D		2	S	-182	3.36	-54		27	D
6/17/25 19:46	6/13/25	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Moyes Jay M	CA	D		2	S	-148	3.37	-44		53	D
6/17/25 19:43	6/13/25	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dorval Allison	CA	D		4	S.d	-94	3.53	-27		89	D
6/17/25 19:41	6/13/25	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cesano Alessandra	CA	D		1	S	-41	3.40	-12		69	D
6/17/25 16:31	6/16/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Porter James Richard	MA	DO	P,CEO	10	S.d	-20,890	80.25	-260		249	D
6/17/25 16:27	6/17/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Malik Fady Ibraham	CA	O	EVP Rese	32	S.d	-12,786	57.69	-222		141	D
6/17/25 16:24	6/13/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hohl Benjamin	CO	O	CFO	27	S.dm	-2,440	23.51	-104		23	D
6/17/25 16:11	6/13/25	CTMX	Cytomx Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ogden Christopher	CA	O	CFO	4	S.dm	-47	1.83	-26		226	D
6/17/25 16:10	6/16/25	CTMX	Cytomx Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Belvin Marcia	CA	O	SVP,Chie	4	S.d	-81	1.61	-50		272	D
6/17/25 16:09	6/16/25	CTMX	Cytomx Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McCarthy Sean A.	CA	DO	CEO	4	S.d	-231	1.82	-127		1,183	D
6/16/25 21:10	6/13/25	VNDA	Vanda Pharmaceuticals Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mitchell Stephen Ray	DC	D		2	S	-58	4.83	-12		97	D
6/16/25 19:35	6/16/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	Montgomery Alan Bruce	CA	D		3	S.dm	-457	24.30	-19		21	D
6/16/25 19:31	6/16/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	Gustafson Kurt A	CA	D		3	S.d	-404	20.71	-19		20	D
6/16/25 19:30	6/16/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	Gorman Kevin Charles	CA	D		2	S.d	-84	14.44	-6		19	D
6/16/25 19:26	6/16/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	Feigal Ellen	CA	D		2	S.d	-79	14.44	-5		19	D
6/16/25 19:22	6/16/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	Ranieri Richard J	CA	D		2	S.d	-79	14.44	-5		19	D
6/16/25 17:47	6/13/25	TGTX	Tg Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Echelard Yann	NC	D		2	S	-859	28.63	-30		229	D
6/16/25 17:24	6/13/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Cook Meredith	MN	O	SVP,GC,S	16	S	-303	61.88	-5		82	D
6/16/25 17:19	6/16/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Blum Robert I	CA	DO	P,CEO	24	S.d	-12,066	47.44	-254		443	D
6/16/25 16:56	6/12/25	ETON	Eton Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Krempa David	IL	O	Chief Bu	1	S.m	-504	14.83	-34		613	D
6/16/25 16:48	6/12/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Betz Stephen F.	CA	O	Chief Sc	11	S.d	-4,560	35.54	-128		109	D
6/16/25 16:42	6/13/25	EOLS	Evolus, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Moatazedi David	CA	DO	See Rema	10	S.dm	-10,742	12.46	-862		792	D
6/16/25 16:03	6/12/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	Kalif Eliyahu Sharon	L3	O	EVP,CFO	3	S.d	-2,904	15.36	-189		403	D
6/16/25 16:03	6/13/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rodman David Malcom	PA	O	Chief Me	8	S.d	-1,852	15.30	-121		141	D
6/16/25 15:40	5/28/25	ANTX	An2 Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Leonard Braden Michael	IN	T		2	S.m	-3,090	1.13	-2,732		3,217	I
6/13/25 20:00	6/13/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	Verdine Gregory L.	MA	D		1	S	-209	6.95	-30		283	D
6/13/25 19:57	6/13/25	ACTU	Actuate Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fletcher Aaron G.L.	TX	DT		7	S.dm	-1,791	4.69	-382		11,157	I
6/13/25 19:50	6/13/25	LTRN	Lantern Pharma Inc.	TX	Health	Drug	Pharmaceutical Preparations	Kreis Leslie W.	TX	T		6	S.dm	-1,602	4.55	-352		11,157	I
6/13/25 16:31	6/11/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Hahn Mark W	X0	O	CFO	13	S.dm	-26,463	6.19	-4,277		14,940	D
6/13/25 16:30	6/11/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Zaccardelli David	X0	DO	P,CEO	13	S.dm	-26,465	6.19	-4,277		15,851	D
6/13/25 16:18	6/11/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fairey William	CA	D		1	S	-155	48.42	-3		3	D
6/12/25 20:42	6/10/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Swisher Daniel N Jr	CA	D		14	S.d	-1,413	49.13	-29	-100	0	D
6/12/25 20:41	6/10/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Guyer William	CA	O	Chief De	12	S.dm	-8,922	52.48	-170		6	D
6/12/25 18:18	6/11/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Flanagan W. Michael	CA	O	Chief Sc	10	S.d	-12,033	39.69	-303		92	D
6/12/25 17:51	6/11/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Ball Titus B.	V8	O	Principa	2	S	-61	223.77	0	0	74	D
6/12/25 17:00	6/10/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sundaram Preethi	FL	O	Chief St	1	S.m	-104	26.41	-4		41	D
6/12/25 16:50	6/10/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	German Christopher Paul	MA	O	Corporat	4	S.d	-209	61.29	-3		3	D
6/12/25 16:21	6/10/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Flammer Martina M.D.	NJ	O	Chief Me	14	S.dm	-33,830	67.15	-504		138	D
6/12/25 16:20	6/10/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Schaeffer Orlov S Nicole	NJ	O	Chief Pe	12	S.dm	-30,902	76.34	-405		121	D
6/11/25 18:25	6/9/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Patel Anish	CO	O	COO	15	S.dm	-3,400	23.13	-147		401	I
6/11/25 17:40	6/9/25	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	Molina Arturo Md	CA	O	Chief Me	5	S.dm	-4,319	49.31	-88		84	D
6/11/25 17:35	6/9/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Quart Barry D	X0	D		1	S.dm	-833	30.35	-27		13	D
6/11/25 17:13	6/9/25	AKBA	Akebia Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Malabre Richard C	MA	O	SVP,Chie	3	S.d	-171	2.92	-59		280	D
6/11/25 17:04	6/9/25	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	Freund John Gordon	MA	D		1	S.d	-202	30.62	-7		114	D
6/11/25 16:15	6/9/25	HROW	Harrow, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T		9	S.m	-2,908	30.61	-95		3,960	I
6/11/25 09:14	6/9/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Schoenberg Mark	NJ	O	Chief Me	5	S.d	-336	12.12	-28		153	D
6/10/25 20:07	6/10/25	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	Binder Steven B.	CT	D		9	S.d	-1,791	5.45	-329		1,115	D
6/10/25 19:28	6/10/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Zecchini Edward J	TN	O	Chief Di	3	S.d	-406	7.23	-56		90	D
6/10/25 19:00	6/9/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jacobson Mark L.	NY	O	COO	5	S.dm	-13,509	92.54	-146		6	D
6/10/25 17:00	6/9/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Palleiko Benjamin L	MA	DO	CEO	13	S.d	-2,145	12.66	-169		315	D
6/10/25 17:00	6/6/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McEnany Patrick J	FL	DH	Chairman	4	S.dm	-23,452	23.45	-1,000		4,478	D
6/10/25 16:45	6/6/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cramer Pamela J.	MA	O	CHRO	12	S.dm	-6,175	51.46	-120		32	D
6/10/25 16:39	6/9/25	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	Nichols Christian Todd	MA	O	SVP,Chie	3	S.m	-655	29.37	-22		86	D
6/10/25 16:30	6/9/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Edgemond James	MD	O	CFO,TREA	15	S.d	-51,810	328.50	-158		8	D
6/9/25 20:49	6/6/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Savage William Jacob	MA	O	Chief Me	8	S.d	-2,300	57.86	-40		68	D
6/6/25 18:04	6/6/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Vazzano Joseph Walter	OH	O	CFO	1	S	-120	6.76	-18		491	D
6/6/25 18:00	6/6/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Seshadri Vishwas	OH	DO	CEO	2	S	-462	6.11	-76		1,355	D
6/6/25 17:58	6/5/25	XENE	Xenon Pharmaceuticals Inc.	A1	Health	Drug	Pharmaceutical Preparations	Gannon Steven	A1	D		2	S.d	-602	46.27	-13		7	D
6/6/25 17:56	6/6/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	O'Malley Brendan M.	OH	O	SVP,GC	1	S	-71	6.76	-10		378	D
6/6/25 16:53	6/5/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Smith Michael Alexander	NJ	O	GC	10	S.dm	-15,157	67.49	-225		97	D
6/6/25 16:47	6/5/25	KRON	Kronos Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Knobelman Deborah	MA	O	P,Interi	1	S	-22	0.8678	-25		139	D
6/6/25 16:20	6/4/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Skorpios Trust	G4	T		4	S	-122,582	11.63	-10,538		10,844	I
6/6/25 16:07	6/5/25	DYN	Dyne Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cox John	MA	DO	CEO,P	2	S	-102	12.59	-8		178	D
6/6/25 16:05	6/5/25	DYN	Dyne Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kerr Douglas	MA	O	Chief Me	2	S	-34	12.59	-3		94	D
6/6/25 16:03	6/5/25	DYN	Dyne Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Friedl-Naderer Johanna	MA	O	Chief Co	2	S	-4	12.74	0	0	96	D
6/5/25 19:25	3/26/25	NTHI	Neonc Technologies Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chiang Ming-Fu (Alan)	CA	D		2	S.ad	-2,868	24.85	-115		2,180	M
6/5/25 19:20	3/26/25	NTHI	Neonc Technologies Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Walters Patrick	CA	O	COO	2	S.ad	-589	24.85	-24		876	I
6/5/25 19:15	3/26/25	NTHI	Neonc Technologies Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Garnett Keithly	CA	DO	CFO	2	S.ad	-329	24.85	-13		321	I
6/5/25 19:10	3/26/25	NTHI	Neonc Technologies Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Heshmatpour Amir F	CA	D		2	S.ad	-1,912	24.85	-77		6,802	I
6/5/25 19:05	3/26/25	NTHI	Neonc Technologies Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chen Thomas C	CA	DOT	CEO	2	S.ad	-1,950	24.85	-78		4,843	I
6/5/25 18:01	6/4/25	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Brege Laura	CA	D		1	S	-315	21.78	-14		15	D
6/5/25 17:40	6/4/25	PCRX	Pacira Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Riker Lauren	CA	O	SVP,Fina	2	S	-260	27.25	-10		60	D
6/5/25 17:37	6/4/25	PCRX	Pacira Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Williams Kristen	CA	O	Chief Ad	2	S	-589	26.97	-22		162	D
6/5/25 17:15	6/3/25	ETON	Eton Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Brynjelsen Sean	IL	DOT	P,CEO	1	S.m	-3,593	17.11	-210		2,874	D
6/5/25 17:08	6/3/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	Shields Matthew	L3	O	EVP,Glob	1	S.d	-106	17.02	-6		10	D
6/5/25 16:50	6/3/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Megna Michael R	X0	O	CHIEF AC	5	S.dm	-1,624	24.86	-65		33	D
6/5/25 16:46	6/3/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Moat Ross	X0	O	CHIEF CO	5	S.dm	-5,509	26.02	-212		22	D
6/5/25 16:42	3/18/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Kaye Edward M. Md	CA	D		6	S.dm	-1,169	13.08	-89		169	D
6/5/25 16:38	6/3/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Ragosa Mark	X0	O	CFO	8	S.dm	-6,040	24.50	-247		27	D
6/5/25 16:38	6/5/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Callos Andrew	CA	O	EVP,Chie	9	S.d	-2,959	41.94	-71		68	D
6/5/25 16:22	6/3/25	BPMC	Blueprint Medicines Corp	DE	Health	Drug	Pharmaceutical Preparations	Carter Percy H.	MA	O	Chief Sc	5	S	-1,541	103.32	-15		57	D
6/5/25 16:20	6/4/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Schundler Russell	NC	O	GC	12	S.d	-697	13.82	-50		597	D
6/5/25 16:20	6/4/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Moomaw Scott	NC	O	Chief Co	13	S.d	-460	14.13	-33		225	D
6/5/25 16:19	6/4/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Saggar Rajeev	NC	O	Chief Me	12	S.d	-575	13.92	-41		273	D
6/5/25 16:18	6/4/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Jeffs Roger	NC	DO	CEO	8	S.dm	-3,996	26.21	-152		2,801	D
6/5/25 16:18	6/4/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Kaseta Michael	NC	O	CFO,COO	12	S.d	-1,035	13.89	-75		412	D
6/5/25 16:16	6/3/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McGirr David W J	MA	D		2	S.dm	-4,719	65.83	-72		101	D
6/5/25 16:16	6/3/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Meeker David P	MA	DO	P,CEO	5	S.d	-5,455	50.59	-108		554	D
6/5/25 16:15	6/4/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Adair Jason	NC	O	Chief Bu	18	S.d	-342	13.82	-25		194	D
6/4/25 20:41	6/2/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Belanoff Joseph K	CA	DO	CEO	5	S.dm	-9,893	82.21	-120		3,019	I
6/4/25 20:34	6/2/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Lyon Joseph Douglas	CA	O	See Rema	15	S.dm	-23,164	86.95	-266		10	D
6/4/25 20:33	6/2/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Maduck Sean	CA	O	See Rema	11	S.dm	-21,407	62.05	-345		117	D
6/4/25 20:30	6/2/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ticho Barry	MA	O	Chief Me	16	S.dm	-1,916	11.82	-162		61	D
6/4/25 18:39	6/2/25	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Petersen Floyd F.	CA	D		10	S.d	-417	39.75	-11		81	D
6/4/25 18:04	6/2/25	TBPH	Theravance Biopharma, Inc.	E9	Health	Drug	Pharmaceutical Preparations	Farnum Rhonda	CA	O	SVP,COMM	6	S	-419	10.15	-41		370	D
6/4/25 16:50	2/3/25	JAZZ	Jazz Pharmaceuticals Plc	L2	Health	Drug	Pharmaceutical Preparations	Cozadd Bruce C	L2	DO	CB,CEO	8	S.m	-2,130	129.11	-17		464	D
6/4/25 16:31	6/3/25	ZTS	Zoetis Inc.		Health	Drug	Pharmaceutical Preparations	Lagano Roxanne	NJ	O	EVP	7	S.dm	-1,298	178.26	-7		18	D
6/4/25 16:11	6/2/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ramasastry Saira	CA	D		3	S.dm	-638	27.50	-23		40	D
6/4/25 15:23	6/4/25	CLNN	Clene Inc.	DE	Health	Drug	Pharmaceutical Preparations	General Resonance LLC	UT	T		10	S.m	-44	0.6848	-64	0	15,428	D
6/3/25 18:34	5/29/25	CKPT	Checkpoint Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fortress Biotech, Inc.	FL	T		1	S.d	-129	1.29	-100	-100	0	D
6/3/25 17:00	5/30/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Daly Richard J	FL	DO	P,CEO	2	S.d	-2,017	23.10	-87		235	D
6/3/25 16:20	6/2/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	Waheed Nadia	MA	O	Chief Me	1	S	-112	8.05	-14		207	D
6/3/25 16:15	5/30/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Smith Hunter C	MA	O	CFO	6	S.d	-2,389	53.26	-45		110	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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