Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	Title	#f	T	TVal	Price	Qty	oc	Own	H
8/26/25 06:10	8/22/25	RNXT	Renovorx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bagai Shaun	CA	DO	CEO	1	P.m	9	0.9297	10	3	330	D
8/25/25 21:33	8/21/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sweeny Nicole	MA	O	Chief Co	2	M.d	25	3.04	8	39	29	D
8/25/25 21:33	8/22/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sweeny Nicole	MA	O	Chief Co	2	S.d	-25	3.04	-8		29	D
8/25/25 21:13	8/21/25	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Williams Laura A	MA	O	Chief Pa	1	S	-37	5.93	-6		396	D
8/25/25 21:12	8/21/25	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Renz Justin A	MA	O	CFO	1	S	-42	5.93	-7		409	D
8/25/25 21:08	8/21/25	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Raab Michael	MA	DO	P,CEO	1	S	-271	5.93	-46		1,528	D
8/25/25 21:03	8/21/25	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Grammer Elizabeth A	MA	O	See Rema	1	S	-35	5.93	-6		306	D
8/25/25 21:02	8/21/25	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Foster Eric Duane	MA	O	Chief Co	1	S	-91	5.93	-15		301	D
8/25/25 20:59	8/21/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Shulman Joseph	MA	O	Chief Te	6	M.d	1,594	49.37	32		9	D
8/25/25 20:59	8/21/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Shulman Joseph	MA	O	Chief Te	6	S.d	-1,594	49.37	-32		9	D
8/25/25 19:46	8/21/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yea Christopher	MA	O	Chief De	5	M.d	541	12.52	43	49	131	D
8/25/25 19:46	8/22/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yea Christopher	MA	O	Chief De	5	S.d	-541	12.52	-43		131	D
8/25/25 19:46	8/21/25	BYSI	Beyondspring Inc.		Health	Drug	Pharmaceutical Preparations	Decheng Capital China Life Sciences Usd Fund Iii, L.P.	CA	T		4	S.m	-1,333	2.90	-460		4,488	I
8/25/25 19:46	8/21/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Palleiko Benjamin L	MA	DO	CEO	7	M.d	824	7.95	104	37	387	D
8/25/25 19:46	8/22/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Palleiko Benjamin L	MA	DO	CEO	7	S.d	-824	7.95	-104		387	D
8/25/25 19:45	8/21/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Audhya Paul K.	MA	O	Chief Me	4	M.d	78	4.18	19	18	120	D
8/25/25 19:45	8/22/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Audhya Paul K.	MA	O	Chief Me	4	S.d	-78	4.18	-19		120	D
8/25/25 19:12	8/22/25	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	Duato Joaquin	NJ	DO	CEO,CB	2	M.d	35,366	140.54	252	161	408	D
8/25/25 19:12	8/22/25	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	Duato Joaquin	NJ	DO	CEO,CB	2	S.d	-35,366	140.54	-252		408	D
8/25/25 17:04	8/21/25	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	Kastelein Johannes Jacob Pieter	P7	DO	Chief Sc	1	S.m	-2,472	24.72	-100		69	I
8/25/25 16:27	8/22/25	AMRX	Amneal Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Shah Nikita	NJ	O	EVP	3	S.m	-2,284	9.42	-243		339	D
8/25/25 16:19	8/22/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Davis Krista	MN	O	SVP,CHRO	1	S	-161	91.10	-2		63	D
8/25/25 09:30	8/21/25	CALC	Calcimedica, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Roberts Eric W	CA	DOT	CHIEF BU	12	P.dm	129	2.06	63	6	1,040	I
8/25/25 08:50	8/22/25	DVAX	Dynavax Technologies Corp	DE	Health	Drug	Pharmaceutical Preparations	Myers Scott Dunseth	CA	D		1	P	41	10.82	4	12	35	D
8/22/25 21:00	8/20/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Venker Eric	X0	O	P,Immuno	8	M.dm	21,111	7.07	2,985		1,654	D
8/22/25 21:00	8/20/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Venker Eric	X0	O	P,Immuno	8	S.dm	-21,111	7.07	-2,985		1,654	D
8/22/25 20:49	8/21/25	DVAX	Dynavax Technologies Corp	DE	Health	Drug	Pharmaceutical Preparations	Deep Track Biotechnology Master Fund, Ltd.	E9	T		1	S.m	-22,352	10.82	-2,065		15,726	D
8/22/25 19:07	8/21/25	SKYE	Skye Bioscience, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Schwab Andrew J.	CA	DT		1	S.m	-801	3.46	-231		9,682	I
8/22/25 19:05	8/21/25	SKYE	Skye Bioscience, Inc.	NV	Health	Drug	Pharmaceutical Preparations	5Am Partners Vii, LLC	CA	T		1	S.m	-801	3.46	-231		9,682	I
8/22/25 18:10	8/20/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Shanmugam Muthusamy	MN	DO	HEAD OF	2	S.m	-17,861	89.30	-200		630	I
8/22/25 17:20	8/22/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hughes Steven George	CA	O	Chief Me	6	M.d	4,266	31.28	136		39	D
8/22/25 17:20	8/22/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hughes Steven George	CA	O	Chief Me	6	S.d	-4,266	31.28	-136		39	D
8/22/25 16:58	8/21/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Trimarchi Thomas	CA	O	P,CFO	2	S	-2,962	49.70	-60		463	D
8/22/25 16:46	8/20/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kumar Neil	CA	DO	CEO	4	S.dm	-8,354	33.30	-251		5,932	D
8/22/25 16:38	8/12/25	AMRX	Amneal Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Boyer Andrew S	NJ	O	EVP	3	S.d	-3,403	6.98	-488		257	D
8/22/25 16:32	8/21/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	14	M.d	33,401	216.89	154		37	D
8/22/25 16:32	8/21/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	14	S.d	-33,401	216.89	-154		37	D
8/22/25 16:30	8/21/25	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lowenthal Richard E	CA	DOT	P,CEO	1	S	-724	14.49	-50	0	11,303	I
8/22/25 16:30	8/21/25	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Scott Kathleen D.	CA	O	CFO	2	M.d	206	8.25	25		18	D
8/22/25 16:30	8/21/25	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Scott Kathleen D.	CA	O	CFO	2	S.d	-206	8.25	-25		18	D
8/22/25 16:19	8/21/25	BHC	Bausch Health Companies Inc.	NJ	Health	Drug	Pharmaceutical Preparations	Lee Frank D.	NJ	D		1	S	-122	7.66	-16		74	D
8/22/25 16:07	8/21/25	LYEL	Lyell Immunopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Seely Lynn	CA	DO	P,CEO	2	S.m	-85	10.53	-8		68	D
8/22/25 16:06	8/21/25	LYEL	Lyell Immunopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hill Stephen J.	CA	O	COO	2	S.m	-13	10.53	-1		16	D
8/22/25 16:03	8/21/25	LYEL	Lyell Immunopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Newton Charles W.	CA	O	CFO	2	S.m	-18	10.53	-2		25	D
8/22/25 16:02	8/21/25	LYEL	Lyell Immunopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lee Gary K.	CA	O	Chief Sc	2	S.m	-18	10.53	-2		16	D
8/22/25 13:27	8/22/25	PRGO	Perrigo Co Plc	L2	Health	Drug	Pharmaceutical Preparations	Willis Robert	MI	O	EVP,CHRO	1	P	36	24.10	1	4	42	D
8/22/25 06:10	8/20/25	DRRX	Durect Corp	DE	Health	Drug	Pharmaceutical Preparations	Asen R Scott	NY	T		1	P.m	387	1.89	204	6	3,637	M
8/21/25 21:32	8/19/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Burnett Patrick	CA	O	See Rema	5	S.dm	-591	8.66	-68		115	D
8/21/25 21:05	8/19/25	NKTR	Nektar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	Zalevsky Jonathan	CA	O	Chief R,	1	S.d	-19	26.59	-1		20	D
8/21/25 21:04	8/19/25	NKTR	Nektar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	Wilson Mark Andrew	CA	O	GC	1	S.d	-18	26.59	-1		20	D
8/21/25 21:03	8/19/25	NKTR	Nektar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	Robin Howard W	CA	DO	P,CEO	1	S.d	-42	26.59	-2		69	D
8/21/25 20:44	8/21/25	CLNN	Clene Inc.	DE	Health	Drug	Pharmaceutical Preparations	General Resonance LLC	UT	T		5	S	-25	4.67	-5		710	D
8/21/25 18:48	8/20/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kintz Samuel	CO	DO	P,CEO	5	S.m	-959	21.32	-45		965	I
8/21/25 18:46	8/19/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lyssikatos Joseph P	CO	O	CHIEF SC	4	S.m	-945	20.99	-45		978	I
8/21/25 17:44	8/21/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sibold William John	PA	DO	P,CEO	1	S	-3,048	400.18	-8		110	D
8/21/25 17:36	8/19/25	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tanimoto Sarina	CA	OT	CHIEF ME	1	S.m	-704	14.08	-50	0	11,353	I
8/21/25 17:22	8/21/25	TNXP	Tonix Pharmaceuticals Holding Corp.	NV	Health	Drug	Pharmaceutical Preparations	Taylor Carolyn E.	NJ	D		1	P	15	36.03	0		0	D
8/21/25 17:07	8/20/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Sharoky Melvin Md	NJ	D		2	S	-2,511	125.54	-20		334	D
8/21/25 17:05	8/19/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Adsett Roger	NJ	O	COO	3	S	-4,379	116.62	-38		141	D
8/21/25 17:00	8/19/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Stefanovich Robert	TN	O	CFO	2	M.d	161	4.54	35	21	207	D
8/21/25 17:00	8/19/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Stefanovich Robert	TN	O	CFO	2	S.d	-161	4.54	-35		207	D
8/21/25 16:30	8/19/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Horobin Joanna	NC	D		1	S	-136	27.17	-5		34	D
8/21/25 16:30	8/20/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pizzuti Dana	CA	O	Chief Me	1	S	-189	29.18	-6		66	D
8/21/25 16:19	8/19/25	MGNX	Macrogenics Inc	DE	Health	Drug	Pharmaceutical Preparations	Heiden William K	MD	D		1	P.m	151	1.51	100	909	111	D
8/21/25 16:15	8/19/25	TNGX	Tango Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Third Rock Ventures Iv, L.P.	MA	T		1	S	-7,713	7.01	-1,100		15,759	D
8/21/25 16:05	8/20/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cloonan Michael	MA	DO	P,CEO	2	M.d	722	14.43	50	10	547	D
8/21/25 16:05	8/20/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cloonan Michael	MA	DO	P,CEO	2	S.d	-722	14.43	-50		547	D
8/21/25 16:04	8/19/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ridloff Elena	MA	O	CFO,Head	1	S.m	-1,124	21.62	-52		72	D
8/21/25 12:00	8/19/25	CALC	Calcimedica, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hebbar Sudarshan	CA	O	Chief Me	2	P.m	43	2.79	16	34	62	D
8/20/25 18:14	8/18/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	EVP,Chie	2	M.d	766	38.29	20	27	93	D
8/20/25 18:14	8/18/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Bennett C Frank	CA	O	EVP,Chie	2	S.d	-766	38.29	-20		93	D
8/20/25 18:12	8/18/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Baker Bros. Advisors LP	NY	D		2	P.m	61,921	373.73	166	9	1,948	I
8/20/25 17:14	8/19/25	ETON	Eton Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gruber James R.	IL	O	CFO	1	S.m	-674	16.15	-42		205	D
8/20/25 17:13	8/18/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	Moreadith Randall	AL	O	Chief Sc	18	M.dm	290	2.79	104		0	D
8/20/25 17:13	8/18/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	Moreadith Randall	AL	O	Chief Sc	18	S.dm	-290	2.79	-104	-100	0	D
8/20/25 17:00	8/18/25	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Militello John	NJ	O	See Rema	2	S.m	-24	3.02	-8		57	D
8/20/25 17:00	8/18/25	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Schwartz Jonathan David	NJ	O	See Rema	2	S.m	-41	3.02	-14		224	D
8/20/25 17:00	8/18/25	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Wilson Martin	NJ	O	GC	2	S.m	-41	3.02	-14		137	D
8/20/25 16:57	8/18/25	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	Dreyer Scott	MA	O	EVP,Chie	4	M.d	1,265	29.75	43	70	104	D
8/20/25 16:57	8/18/25	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	Dreyer Scott	MA	O	EVP,Chie	4	S.d	-1,265	29.75	-43		104	D
8/20/25 16:42	8/18/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Thoma Jeanne	MN	D		1	S	-1,920	89.15	-22		23	D
8/20/25 16:41	8/20/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Pera Antonio R	MN	D		1	S	-486	89.73	-5		30	D
8/20/25 16:38	8/19/25	ZVRA	Zevra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bode John B	FL	D		1	P	46	9.17	5	13	45	D
8/20/25 16:36	8/18/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Tessari Eben	X0	O	COO	10	M.dm	10,834	22.07	491		72	D
8/20/25 16:36	8/18/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Tessari Eben	X0	O	COO	10	S.dm	-10,834	22.07	-491		72	D
8/20/25 16:28	6/16/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Lewis William	NJ	DO	Chair,CE	12	S.dm	-19,214	56.74	-339		593	M
8/20/25 16:28	6/16/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Lewis William	NJ	DO	Chair,CE	12	M.dm	19,214	56.74	339	133	593	M
8/20/25 16:15	8/20/25	TNXP	Tonix Pharmaceuticals Holding Corp.	NV	Health	Drug	Pharmaceutical Preparations	Treco James	NJ	D		1	P	9	36.00	0		0	D
8/20/25 16:13	8/18/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ticho Barry	MA	O	Chief Me	5	S.dm	-244	8.11	-30		27	D
8/20/25 16:12	8/18/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kaye Edward M. Md	MA	D		3	S.d	-338	8.04	-42		195	D
8/20/25 16:11	8/18/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Allan Jonathan	MA	O	GC,Corp	3	S.d	-236	11.05	-21		26	D
8/20/25 16:04	8/19/25	GOSS	Gossamer Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Milligan Sandra	CA	D		1	P	50	1.92	26	81	58	D
8/20/25 16:02	8/18/25	ALXO	Alx Oncology Holdings Inc	DE	Health	Drug	Pharmaceutical Preparations	Shantharam Harish	CA	O	CFO	1	P	58	0.7787	75		75	D
8/20/25 16:01	8/15/25	ARCT	Arcturus Therapeutics Holdings Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sassine Andy	CA	DO	CFO	2	P	41	16.56	2	1	222	D
8/20/25 08:11	8/18/25	PRGO	Perrigo Co Plc	L2	Health	Drug	Pharmaceutical Preparations	Parker Geoffrey M.	MI	D		2	P	201	22.97	9	16	65	I
8/19/25 21:32	8/15/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gangloff Scott A.	CA	O	CTO	2	M.d	98	28.28	3	15	26	D
8/19/25 20:00	8/15/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	Tan Aik Na	MA	D		3	M.d	396	9.18	43		40	D
8/19/25 20:00	8/15/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	Tan Aik Na	MA	D		3	S.d	-396	9.18	-43		40	D
8/19/25 19:40	8/15/25	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	York Charles N II	CA	O	COO,CFO	2	M.d	28	1.32	21	8	278	D
8/19/25 19:40	8/18/25	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	York Charles N II	CA	O	COO,CFO	2	S.d	-28	1.32	-21		278	D
8/19/25 19:38	8/15/25	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dubow Adam	CA	O	GC,Secre	2	M.d	30	1.80	16	43	55	D
8/19/25 19:38	8/18/25	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dubow Adam	CA	O	GC,Secre	2	S.d	-30	1.80	-16		55	D
8/19/25 19:37	8/15/25	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bender Jeremy	CA	DO	CEO	2	M.d	109	2.28	48	3	1,770	D
8/19/25 19:37	8/18/25	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bender Jeremy	CA	DO	CEO	2	S.d	-109	2.28	-48		1,770	D
8/19/25 19:36	8/15/25	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Merendino Lauren	CA	O	Chief Co	2	M.d	25	1.78	14	52	42	D
8/19/25 19:36	8/18/25	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Merendino Lauren	CA	O	Chief Co	2	S.d	-25	1.78	-14		42	D
8/19/25 18:00	8/18/25	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Schneyer Mark C.	CA	O	EVP,CFO	1	S	-554	25.18	-22		40	D
8/19/25 17:28	8/18/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Garg Pushkal	MA	O	EVP Chie	1	S.m	-1,300	455.89	-3		21	D
8/19/25 17:28	8/18/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Tanguler Tolga	MA	O	EVP,Chie	1	S	-633	453.27	-1		29	D
8/19/25 17:27	8/18/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Poulton Jeffrey V.	MA	O	EVP,CFO	1	S	-1,031	453.27	-2		50	D
8/19/25 17:27	8/18/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Greenstreet Yvonne	MA	DO	CEO	3	S.dm	-24,738	227.26	-109		57	D
8/19/25 17:26	8/18/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Fitzgerald Kevin Joseph	MA	O	CSO,EVP,	1	S	-633	453.27	-1		23	D
8/19/25 17:26	8/18/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Bonney Michael W	MA	D		2	M.d	5,852	260.10	23		21	D
8/19/25 17:26	8/18/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Bonney Michael W	MA	D		2	S.d	-5,852	260.10	-23		21	D
8/19/25 17:10	8/15/25	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	Santini Gino	MA	D		2	M.d	403	19.74	20	27	95	D
8/19/25 17:10	8/15/25	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	Santini Gino	MA	D		2	S.d	-403	19.74	-20		95	D
8/19/25 17:02	8/18/25	SEPN	Septerna, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Klein Uwe	CA	O	SVP,Biol	1	M.d	94	4.10	23	22	128	D
8/19/25 16:40	8/18/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Watson David O.	MA	O	GC	3	S	-331	22.04	-15		214	D
8/19/25 16:40	8/15/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Smiley Joshua L	MA	O	See Rema	2	M.d	241	10.68	23	42	77	D
8/19/25 16:40	8/18/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Smiley Joshua L	MA	O	See Rema	2	S.d	-241	10.68	-23		77	D
8/19/25 16:40	8/15/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Edmondson Frazor Titus III	MA	O	GC	4	M.d	281	10.31	27	183	42	D
8/19/25 16:40	8/18/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Edmondson Frazor Titus III	MA	O	GC	4	S.d	-281	10.31	-27		42	D
8/19/25 16:37	8/19/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Malik Fady Ibraham	CA	O	EVP Rese	12	M.d	549	22.86	24	21	141	D
8/19/25 16:37	8/19/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Malik Fady Ibraham	CA	O	EVP Rese	12	S.d	-549	22.86	-24		141	D
8/19/25 16:30	8/15/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Porter James Richard	MA	DO	P,CEO	6	M.d	8,109	50.06	162	186	249	D
8/19/25 16:30	8/15/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Porter James Richard	MA	DO	P,CEO	6	S.d	-8,109	50.06	-162		249	D
8/19/25 16:30	8/15/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Kaseta Michael	NC	O	CFO,COO	8	S.d	-1,554	13.57	-115		412	D
8/19/25 16:15	8/15/25	HRMY	Harmony Biosciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kapadia Sandip	PA	O	CFO	1	S	-787	36.50	-22	-100	0	D
8/19/25 16:12	8/15/25	ALXO	Alx Oncology Holdings Inc	DE	Health	Drug	Pharmaceutical Preparations	Pinto Shelly	CA	O	SVP,Fina	3	S	-2	0.4706	-4		89	D
8/19/25 16:09	8/15/25	ALXO	Alx Oncology Holdings Inc	DE	Health	Drug	Pharmaceutical Preparations	Lettmann Jason	CA	DO	CEO	1	S	-2	0.6402	-2		213	D
8/19/25 16:08	8/15/25	MCRB	Seres Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Shaff Eric D.	MA	D		2	M.d	4	3.84	1	10	11	D
8/19/25 16:08	8/18/25	MCRB	Seres Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Shaff Eric D.	MA	D		2	S.d	-4	3.84	-1		11	D
8/19/25 16:07	8/15/25	MCRB	Seres Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Desrosier Thomas	MA	O	See Rema	2	M.d	1	3.95	0	4	7	D
8/19/25 16:07	8/18/25	MCRB	Seres Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Desrosier Thomas	MA	O	See Rema	2	S.d	-1	3.95	0		7	D
8/19/25 16:07	8/15/25	MCRB	Seres Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Henn Matthew R	MA	O	See Rema	2	M.d	1	3.91	0	7	5	D
8/19/25 16:07	8/18/25	MCRB	Seres Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Henn Matthew R	MA	O	See Rema	2	S.d	-1	3.91	0		5	D
8/19/25 16:06	8/15/25	MCRB	Seres Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Young Teresa L.	MA	O	See Rema	2	M.d	1	3.40	0	6	5	D
8/19/25 16:06	8/18/25	MCRB	Seres Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Young Teresa L.	MA	O	See Rema	2	S.d	-1	3.40	0		5	D
8/19/25 16:01	8/18/25	COYA	Coya Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Goldstein Dov A Md	TX	D		1	M.d	19	1.09	18	176	28	D
8/19/25 10:41	8/18/25	PRGO	Perrigo Co Plc	L2	Health	Drug	Pharmaceutical Preparations	Bezerra Eduardo Guarita	MI	O	EVP,CFO	2	P.d	187	24.80	8	18	49	D
8/18/25 18:19	8/15/25	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	Wolk Joseph J	NJ	O	EVP,CFO	2	M.d	4,689	139.39	34	66	85	D
8/18/25 18:19	8/15/25	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	Wolk Joseph J	NJ	O	EVP,CFO	2	S.d	-4,689	139.39	-34		85	D
8/18/25 18:00	8/14/25	ATAI	Atai Life Sciences N.V.	P7	Health	Drug	Pharmaceutical Preparations	Apeiron Investment Group Ltd.	O1	T		1	P	19,000	2.19	8,676	20	52,845	I
8/18/25 17:33	8/18/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kelley Shannon T	PA	O	GC	1	S	-480	367.81	-1		9	D
8/18/25 17:23	8/18/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Leonard Matthew J	MN	D		1	S	-612	88.17	-7		9	D
8/18/25 17:14	8/15/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bredt David	MA	O	Chief Sc	3	S	-340	13.33	-26		444	D
8/18/25 17:02	8/14/25	SNDX	Syndax Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Podlesak Dennis	NY	D		2	M.dm	1,290	11.20	115	150	192	D
8/18/25 17:02	8/14/25	SNDX	Syndax Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Podlesak Dennis	NY	D		2	S.dm	-1,290	11.20	-115		192	D
8/18/25 16:34	8/15/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Walsh Patrick D	MN	D		1	S	-801	89.05	-9		70	D
8/18/25 16:33	8/15/25	EBS	Emergent Biosolutions Inc.	DE	Health	Drug	Pharmaceutical Preparations	Zoon Kathryn C	MD	D		1	S	-63	8.87	-7		72	D
8/18/25 16:31	8/14/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sensenig Bethany	MD	D		1	S	-227	42.25	-5	-100	0	D
8/18/25 16:29	8/14/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Chen Yajing	MA	O	CFO	6	M.d	575	22.72	25		21	D
8/18/25 16:29	8/15/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Chen Yajing	MA	O	CFO	6	S.d	-575	22.72	-25		21	D
8/18/25 16:29	8/15/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Gassert Chad	MN	O	SVP - CO	1	S	-1,739	86.97	-20		247	I
8/18/25 16:28	8/14/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hudson Frederick M.	MD	D		1	S	-315	42.26	-7		46	D
8/18/25 16:28	8/15/25	EOLS	Evolus, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Stewart Brady	CA	D		1	P	204	6.82	30	51	89	D
8/18/25 16:19	6/10/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Schaeffer Orlov S Nicole	NJ	O	Chief Pe	4	M.dm	15,681	60.92	257		119	D
8/18/25 16:19	6/10/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Schaeffer Orlov S Nicole	NJ	O	Chief Pe	4	S.dm	-15,681	60.92	-257		119	D
8/15/25 19:23	8/13/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bitterman Kevin	MA	D		5	S.m	-5,166	61.06	-85		1,148	I
8/15/25 18:13	8/15/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Hussain Iqbal J	X0	O	GC	6	M.d	501	10.44	48	76	111	D
8/15/25 18:13	8/15/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Hussain Iqbal J	X0	O	GC	6	S.d	-501	10.44	-48		111	D
8/15/25 18:04	8/15/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bate Kenneth	PA	D		2	M.d	3,817	190.83	20		3	D
8/15/25 18:04	8/15/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bate Kenneth	PA	D		2	S.d	-3,817	190.83	-20		3	D
8/15/25 17:59	8/13/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hamilton James C	CA	O	Chief Me	1	S.m	-200	20.00	-10		262	D
8/15/25 17:50	8/15/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McCarthy Teresa	CA	O	CHRO	2	M.d	689	34.45	20	26	97	D
8/15/25 17:50	8/15/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McCarthy Teresa	CA	O	CHRO	2	S.d	-689	34.45	-20		97	D
8/15/25 17:05	8/13/25	MGNX	Macrogenics Inc	DE	Health	Drug	Pharmaceutical Preparations	Koenig Scott	MD	D		1	M.d	0	0.00	53	7	830	D
8/15/25 17:00	8/13/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Shelton Jerrell	TN	DO	P,CEO	12	M.dm	5,935	5.59	1,062	999%	1,062	D
8/15/25 16:57	8/13/25	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	Johnson John	IL	D		1	S	-786	7.32	-108		833	D
8/15/25 16:40	6/23/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Wu Xiaobin	V8	O	P,COO	5	S.dm	-43,196	233.42	-185		1,262	D
8/15/25 16:38	7/30/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Lee Chan Henry	V8	O	SVP,GC	5	S.d	-5,345	251.11	-21		278	D
8/15/25 16:30	8/14/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Crombez Eric	OH	D		1	S	-33	6.93	-5		42	D
8/15/25 16:30	7/22/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Vazzano Joseph Walter	OH	O	CFO	4	S	-389	6.52	-60		491	D
8/15/25 16:30	8/13/25	AMRX	Amneal Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Konidaris Tasos	NJ	O	EVP,CFO	1	S.m	-4,663	9.33	-500		122	D
8/15/25 16:23	8/15/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Blum Robert I	CA	DO	P,CEO	6	S	-1,058	35.27	-30		412	D
8/15/25 16:13	8/15/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	Montarce Lucas	IN	O	EVP,CFO	1	P	495	691.79	1	5	15	D
8/15/25 16:12	8/13/25	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	Rubric Capital Management LP	NY	T		2	S.d	-4,527	1.88	-2,412		32,233	I
8/15/25 16:09	8/13/25	ALDX	Aldeyra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Alfieri Michael	MA	O	Principa	1	P	13	5.30	3		3	D
8/15/25 16:09	8/6/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Maclean Michael F	CA	O	CFO	1	S	-1,321	42.73	-31		66	D
8/15/25 16:05	8/14/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Ausiello Dennis A	MA	D		2	M.d	17,860	283.96	63		4	D
8/15/25 16:05	8/14/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Ausiello Dennis A	MA	D		2	S.d	-17,860	283.96	-63		4	D
8/15/25 12:45	8/13/25	NATR	Natures Sunshine Products Inc	UT	Health	Drug	Pharmaceutical Preparations	Lanoy Jonathan David	UT	O	SVP,Chie	1	S	-83	16.51	-5		50	D
8/15/25 12:12	8/13/25	NATR	Natures Sunshine Products Inc	UT	Health	Drug	Pharmaceutical Preparations	Brower Nathan G	UT	O	EVP,GC	1	S	-165	16.54	-10		48	D
8/14/25 21:35	8/14/25	BHC	Bausch Health Companies Inc.	NJ	Health	Drug	Pharmaceutical Preparations	Paulson John	FL	D		4	P.m	369,629	8.34	44,317	168	70,756	I
8/14/25 19:43	8/12/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Moore John R	CO	O	GC	2	M.d	28	3.57	8	337	10	D
8/14/25 19:43	8/12/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Moore John R	CO	O	GC	2	S.d	-28	3.57	-8		10	D
8/14/25 19:43	8/12/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Derakhshan Behrad	CO	O	Chief Bu	2	M.d	33	4.03	8	54	24	D
8/14/25 19:43	8/12/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Derakhshan Behrad	CO	O	Chief Bu	2	S.d	-33	4.03	-8		24	D
8/14/25 19:43	8/12/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Carruthers R Michael	CO	O	CFO	2	M.d	19	2.65	7	9	86	D
8/14/25 19:43	8/12/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Carruthers R Michael	CO	O	CFO	2	S.d	-19	2.65	-7		86	D
8/14/25 19:42	8/12/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Russell Alan J	CO	DO	Chief Sc	2	M.d	26	3.32	8	49	23	D
8/14/25 19:42	8/12/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Russell Alan J	CO	DO	Chief Sc	2	S.d	-26	3.32	-8		23	D
8/14/25 19:42	8/12/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Koch Kevin	CO	DO	P,CEO	2	M.d	107	4.12	26	8	369	D
8/14/25 19:42	8/12/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Koch Kevin	CO	DO	P,CEO	2	S.d	-107	4.12	-26		369	D
8/14/25 19:41	8/12/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Donovan Joanne M.	CO	O	CMO	2	M.d	38	4.43	9	52	25	D
8/14/25 19:41	8/12/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Donovan Joanne M.	CO	O	CMO	2	S.d	-38	4.43	-9		25	D
8/14/25 18:48	8/12/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Smith Hunter C	MA	O	CFO	7	M.dm	8,223	42.35	194		117	D
8/14/25 18:48	8/12/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Smith Hunter C	MA	O	CFO	7	S.dm	-8,223	42.35	-194		117	D
8/14/25 18:47	8/12/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	German Christopher Paul	MA	O	Corporat	6	M.d	729	56.96	13		2	D
8/14/25 18:47	8/12/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	German Christopher Paul	MA	O	Corporat	6	S.d	-729	56.96	-13		2	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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