Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	Title	#f	T	TVal	Price	Qty	oc	Own	H
7/1/25 17:03	6/27/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tpg Gp A, LLC	TX	T		1	P	950	15.84	60	1	6,745	I
7/1/25 17:01	6/30/25	AKBA	Akebia Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ostrowski Erik	MA	O	SVP,CFO,	1	S	-152	3.67	-41		504	D
7/1/25 16:55	6/30/25	ANNX	Annexon, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Carson William H.	CA	D		1	P	10	2.46	4	16	30	D
7/1/25 16:50	6/27/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Savage William Jacob	MA	O	Chief Me	4	M.d	906	20.65	44	98	89	D
7/1/25 16:49	6/27/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Abi-Saab Walid	P7	O	Chief Me	1	S	-20	13.92	-1		150	D
7/1/25 16:42	6/27/25	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Flynn James E	NY	T		1	S	-13,663	18.46	-740		9,775	I
7/1/25 16:42	6/27/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hohl Benjamin	CO	O	CFO	8	M.d	281	11.00	26		23	D
7/1/25 16:42	6/27/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hohl Benjamin	CO	O	CFO	8	S.d	-281	11.00	-26		23	D
7/1/25 16:37	6/27/25	CLYM	Climb Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Brennan Aoife	MA	DO	P,CEO	2	M.d	25	0.2815	89		48	D
7/1/25 16:37	6/30/25	CLYM	Climb Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Brennan Aoife	MA	DO	P,CEO	2	S.d	-25	0.2815	-89		48	D
7/1/25 16:32	6/27/25	CLYM	Climb Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Thomas Stephen Basil	MA	D		1	M.d	0	0.00	25	14	204	D
7/1/25 16:30	6/27/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Du Ying	MA	DO	Chairper	12	M.dm	7,210	13.61	530		526	D
7/1/25 16:30	6/30/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Du Ying	MA	DO	Chairper	12	S.dm	-7,210	13.61	-530		526	D
7/1/25 16:30	6/27/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Balcom Alexandra	MA	O	CFO	2	M.d	1,979	49.48	40	184	62	D
7/1/25 16:30	6/27/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Balcom Alexandra	MA	O	CFO	2	S.d	-1,979	49.48	-40		62	D
7/1/25 16:22	6/30/25	ALXO	Alx Oncology Holdings Inc	DE	Health	Drug	Pharmaceutical Preparations	Pinto Shelly	CA	O	SVP,Fina	1	S	-1	0.4302	-2		89	D
7/1/25 16:08	6/30/25	INO	Inovio Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sumner Michael John	PA	O	Chief Me	2	M.d	0	0.00	5	42	18	D
6/30/25 21:30	6/26/25	AMRN	Amarin Corp Plcuk	X0	Health	Drug	Pharmaceutical Preparations	Berg Aaron	NJ	O	P,CEO	1	M.d	0	0.00	75	999%	81	D
6/30/25 17:51	6/26/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Valantine Hannah	CA	D		5	S.d	-506	29.11	-17		8	M
6/30/25 17:38	6/27/25	TERN	Terns Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gengos Andrew	CA	O	CFO	2	P.m	96	3.85	25		25	D
6/30/25 17:02	6/26/25	ZVRA	Zevra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Thompson Rahsaan	FL	OH	Chief Le	2	S.d	-221	2.44	-91		67	D
6/30/25 16:30	6/30/25	BTAI	Bioxcel Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mack David J.	CT	D		3	M.d	0	0.00	5	60	14	D
6/30/25 13:03	6/27/25	ACTU	Actuate Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bios Equity Cof, LP	TX	DT		1	P.d	500	7.00	71	1	10,196	I
6/30/25 13:02	6/27/25	ACTU	Actuate Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kreis Leslie W.	TX	DT		4	P.dm	1,000	4.36	229	2	11,374	I
6/30/25 13:01	6/27/25	ACTU	Actuate Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fletcher Aaron G.L.	TX	DT		4	P.dm	1,000	4.36	229	2	11,374	I
6/30/25 09:09	6/27/25	IMRX	Immuneering Corp	DE	Health	Drug	Pharmaceutical Preparations	Schall Thomas J.	MA	D		2	P	124	2.48	50	999%	53	D
6/27/25 19:35	6/26/25	CALC	Calcimedica, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Roberts Eric W	CA	DOT	CHIEF BU	3	P.m	33	1.70	20	2	997	I
6/27/25 17:07	6/26/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Noci Darlene	MA	O	Chief De	6	M.d	1,150	47.92	24	100	48	D
6/27/25 17:07	6/26/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Noci Darlene	MA	O	Chief De	6	S.d	-1,150	47.92	-24		48	D
6/27/25 17:05	6/25/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pelish Henry E.	MA	O	Chief Sc	4	M.dm	1,195	54.33	22	54	63	D
6/27/25 17:05	6/25/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pelish Henry E.	MA	O	Chief Sc	4	S.dm	-1,195	54.33	-22		63	D
6/27/25 16:39	6/26/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	14	M.d	32,325	209.90	154		37	D
6/27/25 16:39	6/26/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	14	S.d	-32,325	209.90	-154		37	D
6/27/25 16:27	6/27/25	NATR	Natures Sunshine Products Inc	UT	Health	Drug	Pharmaceutical Preparations	Shanghai Fosun Pharmaceutical (Group) Co., Ltd.	F4	T		1	S	-32,714	11.46	-2,855		64	I
6/27/25 16:15	6/25/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Edmondson Frazor Titus III	MA	O	GC	6	M.d	431	8.80	49		39	D
6/27/25 16:15	6/26/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Edmondson Frazor Titus III	MA	O	GC	6	S.d	-431	8.80	-49		39	D
6/27/25 16:15	6/25/25	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	Lee Ting-Chuan	CA	D		1	S	-1	0.5100	-3	0	1,429	D
6/27/25 16:15	6/25/25	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	Tsai Chun-Jung	CA	D		2	S.m	-22	0.5166	-43		1,402	D
6/27/25 16:15	6/25/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Chen Yajing	MA	O	CFO	7	M.d	605	14.24	43		27	D
6/27/25 16:15	6/26/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Chen Yajing	MA	O	CFO	7	S.d	-605	14.24	-43		27	D
6/26/25 20:00	6/24/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Shelton Jerrell	TN	DO	P,CEO	7	M.dm	5,310	5.67	937	999%	937	D
6/26/25 20:00	6/24/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Shelton Jerrell	TN	DO	P,CEO	7	S.dm	-5,310	5.67	-937		937	D
6/26/25 20:00	6/24/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kharabi Darius	MA	O	CHIEF BU	2	S	-21	3.97	-5		67	D
6/26/25 20:00	6/24/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Mandalam Ramkumar	TN	D		4	M.dm	270	5.43	50	181	77	D
6/26/25 20:00	6/24/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Mandalam Ramkumar	TN	D		4	S.dm	-270	5.43	-50		77	D
6/26/25 20:00	6/24/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Reumuth Mary	MA	O	CFO	2	S	-25	3.89	-6		66	D
6/26/25 20:00	6/24/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bazemore Todd	MA	O	SEE REMA	2	S	-29	3.89	-7		88	D
6/26/25 20:00	6/24/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Brazzell Romulus K	MA	O	SEE REMA	2	S	-35	3.90	-9		88	D
6/26/25 20:00	6/24/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Iwicki Mark T	MA	D		3	S	-134	3.84	-35		269	D
6/26/25 19:50	6/23/25	KANT	Kineta, Inc./De	DE	Health	Drug	Pharmaceutical Preparations	Iadonato Shawn	WA	D		1	M.d	89	0.3732	238	38	869	D
6/26/25 19:41	6/24/25	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	Topper James N	CA	D		5	P.m	429	5.98	72	1	12,750	I
6/26/25 18:30	6/26/25	CALC	Calcimedica, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bardin Stephen	CA	O	CFO	2	P.d	5	1.57	3	8	43	I
6/26/25 17:26	6/24/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Burns James William	MA	O	GC	2	M.d	94	10.67	9	44	29	D
6/26/25 17:26	6/24/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Burns James William	MA	O	GC	2	S.d	-94	10.67	-9		29	D
6/26/25 17:25	6/24/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gheuens Sarah	MA	O	Chief Me	2	M.d	98	10.95	9	19	57	D
6/26/25 17:25	6/24/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gheuens Sarah	MA	O	Chief Me	2	S.d	-98	10.95	-9		57	D
6/26/25 17:24	6/24/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jones Cecilia	MA	O	CFO	2	M.d	60	7.67	8	35	30	D
6/26/25 17:24	6/24/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jones Cecilia	MA	O	CFO	2	S.d	-60	7.67	-8		30	D
6/26/25 17:23	6/24/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Milanova Tsveta	MA	O	Chief Co	2	M.d	93	10.59	9	51	26	D
6/26/25 17:23	6/24/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Milanova Tsveta	MA	O	Chief Co	2	S.d	-93	10.59	-9		26	D
6/26/25 17:22	6/24/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Goff Brian	MA	DO	CEO	2	M.d	627	11.01	57	104	112	D
6/26/25 17:22	6/24/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Goff Brian	MA	DO	CEO	2	S.d	-627	11.01	-57		112	D
6/26/25 17:08	6/24/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McCormick Frank	CA	D		1	S	-4,423	44.23	-100		963	I
6/26/25 09:07	6/25/25	RZLT	Rezolute, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Roberts Brian Kenneth	CA	O	Chief Me	1	P	11	4.38	3	1	174	D
6/25/25 21:55	6/23/25	KANT	Kineta, Inc./De	DE	Health	Drug	Pharmaceutical Preparations	Drapkin Kimberlee C	WA	D		1	M.d	8	0.6110	13	966	14	D
6/25/25 21:54	6/23/25	KANT	Kineta, Inc./De	DE	Health	Drug	Pharmaceutical Preparations	Peters Richard	WA	D		1	M.d	8	0.6110	13	14	102	D
6/25/25 21:52	6/23/25	KANT	Kineta, Inc./De	DE	Health	Drug	Pharmaceutical Preparations	Foote Marion R	WA	D		2	M.d	9	0.4250	21	14	165	D
6/25/25 21:52	6/23/25	KANT	Kineta, Inc./De	DE	Health	Drug	Pharmaceutical Preparations	Dylla Scott J.	WA	D		1	M.d	8	0.6110	13	236	18	D
6/25/25 21:49	6/23/25	KANT	Kineta, Inc./De	DE	Health	Drug	Pharmaceutical Preparations	Arkowitz David	WA	D		1	M.d	8	0.6110	13	222	18	D
6/25/25 21:47	6/23/25	KANT	Kineta, Inc./De	DE	Health	Drug	Pharmaceutical Preparations	Philips Craig W.	WA	O	P,Secret	1	M.d	81	0.3600	225	208	333	D
6/25/25 21:46	6/23/25	KANT	Kineta, Inc./De	DE	Health	Drug	Pharmaceutical Preparations	Guillaudeux Thierry	WA	O	Chief Sc	1	M.d	81	0.3600	225		217	D
6/25/25 21:45	6/23/25	KANT	Kineta, Inc./De	DE	Health	Drug	Pharmaceutical Preparations	Bartoszek Raymond J.	WA	D		1	M.d	8	0.6110	13	1	1,781	D
6/25/25 21:43	6/23/25	KANT	Kineta, Inc./De	DE	Health	Drug	Pharmaceutical Preparations	Baker Keith	WA	O	CFO	1	M.d	81	0.3600	225	981	248	D
6/25/25 20:07	6/23/25	VERA	Vera Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Enright Patrick G	CA	D		1	P.m	5,277	21.11	250	7	3,597	I
6/25/25 19:44	6/25/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Weinhoff Gregory M	X0	O	Chief Bu	5	M.d	504	9.74	52	73	122	D
6/25/25 19:44	6/25/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Weinhoff Gregory M	X0	O	Chief Bu	5	S.d	-504	9.74	-52		122	D
6/25/25 19:43	6/24/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Hussain Iqbal J	X0	O	GC	6	M.dm	357	9.93	36	48	111	D
6/25/25 19:43	6/24/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Hussain Iqbal J	X0	O	GC	6	S.dm	-357	9.93	-36		111	D
6/25/25 19:42	6/24/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Accardi Mario Alberto	X0	O	P,Orexin	2	M.d	268	8.93	30	16	216	D
6/25/25 19:42	6/24/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Accardi Mario Alberto	X0	O	P,Orexin	2	S.d	-268	8.93	-30		216	D
6/25/25 18:52	6/23/25	OKUR	Onkure Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Saccomano Nicholas A	CO	DO	P,CEO	2	S.m	-3	2.89	-1		4	D
6/25/25 18:49	6/23/25	OKUR	Onkure Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Leverone Jason A.	CO	O	CFO	2	S.m	-10	2.89	-3		13	D
6/25/25 18:08	6/25/25	TERN	Terns Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Burroughs Amy L.	CA	DO	CEO	1	P	90	3.87	23	98	47	D
6/25/25 17:09	6/23/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Wang Lai	V8	O	Global H	3	S.m	-1,053	258.24	-4	0	1,769	D
6/25/25 17:08	6/23/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Wu Xiaobin	V8	O	P,COO	5	S.dm	-24,181	221.21	-109		1,262	D
6/25/25 17:08	6/24/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Wang Xiaodong	V8	DH	Chair, S	7	S.d	-31,789	125.87	-253		10,159	D
6/25/25 17:06	6/23/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Oyler John	V8	DO	CEO	4	S.dm	-5,508	1.35	-4,069		54,270	D
6/25/25 17:01	6/23/25	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	Taiwan Carbon Nano Technology Corp	F5	T		1	S	0	0.00	-29		5,471	D
6/25/25 16:38	6/24/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mesa Nilda	MD	D		1	S	-187	289.99	-1		5	D
6/25/25 16:36	6/24/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Giltner Richard	MD	D		2	M.d	1,756	218.56	8	71	19	D
6/25/25 16:36	6/24/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Giltner Richard	MD	D		2	S.d	-1,756	218.56	-8		19	D
6/25/25 16:30	6/23/25	AKTX	Akari Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Gaslightwala Abizer	MA	DO	P,CEO	3	P.m	37	1.19	31	13	278	D
6/25/25 16:18	6/23/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Bonstein Sara	NJ	O	CFO	6	M.dm	13,629	61.01	223		113	D
6/25/25 16:18	6/23/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Bonstein Sara	NJ	O	CFO	6	S.dm	-13,629	61.01	-223		113	D
6/25/25 06:03	6/23/25	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	Ase Test, Inc.	F5	T		1	P	0	0.00	29	100	59	D
6/24/25 21:01	6/20/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Venker Eric	NY	O	P,COO	8	M.dm	20,904	7.00	2,985		1,462	D
6/24/25 21:01	6/20/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Venker Eric	NY	O	P,COO	8	S.dm	-20,904	7.00	-2,985		1,462	D
6/24/25 20:29	6/23/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Reardon Andrew	FL	O	CLO,Secr	3	S	-218	109.16	-2		33	D
6/24/25 18:33	6/23/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Piscitelli Dominic	CA	O	CFO	4	S.m	-416	10.41	-40		104	D
6/24/25 18:08	6/20/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Springhorn Jeremy P.	P7	D		1	S	-31	14.45	-2		38	D
6/24/25 18:05	6/20/25	AVIR	Atea Pharmaceuticals, Inc.	MA	Health	Drug	Pharmaceutical Preparations	Murphy Polly A.	MA	D		1	M.d	0	0.00	30	52	86	D
6/24/25 18:05	6/20/25	AVIR	Atea Pharmaceuticals, Inc.	MA	Health	Drug	Pharmaceutical Preparations	Berger Franklin M	MA	D		1	M.d	0	0.00	30	6	506	D
6/24/25 18:05	6/20/25	AVIR	Atea Pharmaceuticals, Inc.	MA	Health	Drug	Pharmaceutical Preparations	Duncan Barbara Gayle	MA	D		1	M.d	0	0.00	30	89	63	D
6/24/25 18:05	6/20/25	AVIR	Atea Pharmaceuticals, Inc.	MA	Health	Drug	Pharmaceutical Preparations	Polsky Bruce	MA	D		1	M.d	0	0.00	30	45	95	D
6/24/25 18:05	6/20/25	AVIR	Atea Pharmaceuticals, Inc.	MA	Health	Drug	Pharmaceutical Preparations	Adams Jerome M.	MA	D		1	M.d	0	0.00	30	89	63	D
6/24/25 18:05	6/20/25	AVIR	Atea Pharmaceuticals, Inc.	MA	Health	Drug	Pharmaceutical Preparations	Lucidi Bruno	MA	D		1	M.d	0	0.00	30	36	113	D
6/24/25 18:03	6/20/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Post Leonard E	P7	D		1	S	-31	14.45	-2		30	D
6/24/25 17:53	6/20/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Kaye Jack	P7	D		1	S	-31	14.45	-2		20	D
6/24/25 17:50	6/20/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Jacques Rachelle Suzanne	P7	D		1	S	-31	14.45	-2		28	D
6/24/25 17:45	6/20/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Gut Robert	P7	D		1	S	-48	14.45	-3		57	D
6/24/25 17:42	6/20/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Balachandran Madhavan	P7	D		1	S	-31	14.45	-2		38	D
6/24/25 17:36	6/20/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lyssikatos Joseph P	CO	O	CHIEF SC	5	S.m	-730	19.47	-38		998	I
6/24/25 17:34	6/20/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Meek David D.	P7	D		1	S	-31	14.45	-2		34	D
6/24/25 17:14	6/20/25	NVCT	Nuvectis Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mosseri Marlio Charles	N1	T		5	P.m	969	8.40	115	4	3,091	I
6/24/25 16:39	6/20/25	VSTM	Verastem, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Paterson Dan	MA	DO	P,CEO	4	S	-576	7.42	-78		462	D
6/24/25 16:37	6/20/25	VSTM	Verastem, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Calkins Daniel	MA	O	CFO	2	S.m	-112	7.32	-15		114	D
6/24/25 16:08	6/24/25	ARVN	Arvinas, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Saik Andrew	CT	O	CFO	1	S	-43	7.61	-6		164	D
6/24/25 16:00	6/20/25	MRUS	Merus N.V.	P7	Health	Drug	Pharmaceutical Preparations	Silverman Peter B.	P7	O	COO,GC	2	M.d	2,427	35.69	68		0	D
6/24/25 16:00	6/20/25	MRUS	Merus N.V.	P7	Health	Drug	Pharmaceutical Preparations	Silverman Peter B.	P7	O	COO,GC	2	S.d	-2,427	35.69	-68	-100	0	D
6/24/25 12:41	6/24/25	RZLT	Rezolute, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Evans Daron	CA	O	CFO	1	P	20	4.05	5	1	361	D
6/24/25 09:01	6/20/25	IMRX	Immuneering Corp	DE	Health	Drug	Pharmaceutical Preparations	Hall Brett Matthew	MA	O	CHIEF SC	1	P.m	35	2.58	13	4	359	D
6/24/25 08:52	6/20/25	IMRX	Immuneering Corp	DE	Health	Drug	Pharmaceutical Preparations	Brakewood Harold Eugene	MA	O	Chief Bu	1	P	5	2.53	2	49	6	D
6/23/25 21:29	6/20/25	THAR	Tharimmune, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gravitas Capital LP	NJ	DOT	Exec CB	1	P	500	1.48	338	86	732	D
6/23/25 20:05	6/20/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	You Angie	CA	D		1	P.m	263	9.39	28		28	D
6/23/25 19:42	6/20/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Murdock Hunter R.	NY	O	GC	4	M.dm	4,725	65.60	72		0	D
6/23/25 19:42	6/20/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Murdock Hunter R.	NY	O	GC	4	S.dm	-4,725	65.60	-72	-100	0	D
6/23/25 19:34	6/20/25	THAR	Tharimmune, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Parikh Sanam	NJ	D		2	P	2	1.38	2		2	D
6/23/25 19:31	6/20/25	THAR	Tharimmune, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Appajosyula Sireesh	NJ	DO	CEO	1	P	91	1.48	61	999%	65	D
6/23/25 16:57	6/18/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mathers Edward T	NY	D		1	M.d	0	0.00	4	46	13	D
6/23/25 16:53	6/18/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jean Christophe	MA	D		1	M.d	0	0.00	4	133	7	D
6/23/25 16:53	6/18/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Good Jennifer L	MA	D		1	M.d	0	0.00	4	133	7	D
6/23/25 16:52	6/18/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bedrosian Camille L	MA	D		1	M.d	0	0.00	4	133	7	D
6/23/25 16:51	6/18/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Arbuckle Stuart A	MA	D		1	M.d	0	0.00	4	133	7	D
6/23/25 16:49	6/3/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McGirr David W J	MA	D		4	S.dm	-5,019	35.57	-141		105	D
6/23/25 16:48	6/18/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tetrault Lynn A.	MA	D		1	M.d	0	0.00	4	133	7	D
6/23/25 16:35	6/20/25	MBRX	Moleculin Biotech, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Foster Jonathan P.	TX	O	CFO	3	M.dm	100	0.3595	278	999%	288	D
6/23/25 16:35	6/23/25	MBRX	Moleculin Biotech, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Foster Jonathan P.	TX	O	CFO	3	P.dm	100	0.3595	278	999%	288	D
6/23/25 16:35	6/20/25	MBRX	Moleculin Biotech, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Klemp Walter V	TX	DO	CEO,P	3	M.dm	250	0.3623	690	999%	744	D
6/23/25 16:35	6/23/25	MBRX	Moleculin Biotech, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Klemp Walter V	TX	DO	CEO,P	3	P.dm	250	0.3623	690	999%	744	D
6/23/25 16:34	6/20/25	MBRX	Moleculin Biotech, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Picker Donald H	TX	O	Chief Sc	1	M.dm	0	0.00	3	39	10	D
6/23/25 16:27	6/20/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ballal Rahul D.	MA	D		1	M.d	0	0.00	2	27	10	D
6/23/25 16:25	6/20/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Capello Jeffrey D	MA	D		2	M.d	0	0.00	4	207	6	D
6/23/25 16:24	6/20/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Foster-Cheek Kaye I	MA	D		1	M.d	0	0.00	2	28	10	D
6/23/25 16:23	6/20/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fouse Jacqualyn A	MA	D		3	M.d	194	7.60	26	20	151	D
6/23/25 16:21	6/20/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ho Maykin	MA	D		1	M.d	0	0.00	2	14	17	D
6/23/25 16:20	6/20/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Owen Adams Catherine	MA	D		2	M.d	0	0.00	4	207	6	D
6/23/25 16:18	6/20/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Scadden David	MA	D		1	M.d	0	0.00	2	14	18	D
6/23/25 16:17	6/20/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Smith Cynthia	MA	D		1	M.d	0	0.00	2	27	10	D
6/23/25 16:10	6/20/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Lis William	MA	D		1	S	-493	35.67	-14		35	D
6/23/25 14:39	6/20/25	SVRA	Savara Inc	DE	Health	Drug	Pharmaceutical Preparations	Hawkins Richard J	PA	D		1	P	99	2.04	48	72	115	D
6/23/25 13:50	6/20/25	RARE	Ultragenyx Pharmaceutical Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sanders Corazon (Corsee) D.	CA	D		1	S	-90	37.39	-2		15	D
6/23/25 11:35	6/18/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Ramaswamy Vivek	DC	T		3	S.m	-31,669	11.35	-2,789		52,532	D
6/23/25 09:38	6/13/25	RZLT	Rezolute, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Kim Young-Jin	CA	D		1	P	4,000	3.25	1,231	17	8,573	I
6/23/25 09:12	6/13/25	RZLT	Rezolute, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Kreher Nerissa	CA	D		1	P	10	3.25	3	9	38	D
6/23/25 09:09	6/18/25	IMRX	Immuneering Corp	DE	Health	Drug	Pharmaceutical Preparations	Feinberg Peter	MA	D		1	P	63	2.53	25	2	1,121	D
6/20/25 21:09	6/18/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cheng Andrew	CA	DO	P,CEO	4	S	-4,709	45.08	-104		624	D
6/20/25 21:08	6/18/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gangloff Scott A.	CA	O	CTO	1	S	-47	54.84	-1		23	D
6/20/25 21:08	6/20/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lamy Patrick	CA	O	SVP,Comm	10	S.d	-1,403	37.11	-38		33	D
6/20/25 21:07	6/18/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rolph Timothy	CA	O	Chief Sc	10	S.dm	-4,576	35.61	-128		170	D
6/20/25 21:07	6/18/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	White William Richard	CA	O	CFO	2	S	-241	54.31	-4		59	D
6/20/25 21:07	6/18/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yale Catriona	CA	O	Chief De	8	S.d	-2,134	34.09	-63		95	D
6/20/25 21:06	6/18/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Young Jonathan	CA	O	COO	2	S	-214	54.31	-4		258	D
6/20/25 20:58	6/20/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Saha Saurabh	X0	DO	CEO	5	M.dm	2,499	9.09	275		259	D
6/20/25 20:58	6/20/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Saha Saurabh	X0	DO	CEO	5	S.dm	-2,499	9.09	-275		259	D
6/20/25 20:24	6/16/25	IGMS	Igm Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Weber Steven	CA	O	Principa	2	S	-3	1.14	-2		27	D
6/20/25 20:23	6/16/25	IGMS	Igm Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tahir Misbah	CA	O	CFO	1	S	-2	1.20	-2		179	D
6/20/25 20:20	6/16/25	IGMS	Igm Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Harler Mary Beth	CA	DO	CEO	1	S	-2	1.20	-2	0	338	D
6/20/25 20:19	6/16/25	IGMS	Igm Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Decker Lisa Lynn	CA	O	Chief Bu	1	S	-1	1.20	-1		73	D
6/20/25 19:43	6/16/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Potts Jeannette		O	GC	1	S	-71	15.14	-5		115	D
6/20/25 18:38	6/18/25	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Karas Eric	CA	O	Chief Co	2	M.d	263	8.75	30		8	D
6/20/25 18:38	6/18/25	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Karas Eric	CA	O	Chief Co	2	S.d	-263	8.75	-30		8	D
6/20/25 17:42	6/17/25	TYRA	Tyra Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kaplan Gilla	CA	D		2	S.m	-628	10.23	-61		38	D
6/20/25 17:16	6/5/25	IMUX	Immunic, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tardio Jason	NY	O	P,COO	2	P.d	20	0.7900	25		13	D
6/20/25 17:15	6/4/25	IMUX	Immunic, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Vitt Daniel	NY	DO	CEO,Dir	2	P.d	23	0.7700	30	8	392	D
6/20/25 16:32	6/18/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Welgus Howard G.	CA	D		3	S	-433	14.37	-30		122	D
6/20/25 16:20	6/18/25	CLYM	Climb Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pimblett Emily	MA	O	SVP,Fina	2	M.d	2	0.2467	6	49	19	D
6/20/25 16:20	6/20/25	CLYM	Climb Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pimblett Emily	MA	O	SVP,Fina	2	S.d	-2	0.2467	-6		19	D
6/20/25 16:08	6/18/25	NKTX	Nkarta, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hastings Paul J	CA	DO	CEO	1	S	-3	1.79	-2		320	D
6/20/25 16:07	6/18/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Fenton Dennis M	CA	D		2	S.d	-72	7.99	-9		8	D
6/20/25 16:06	6/18/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Renton Hollings	CA	D		2	S.d	-72	7.99	-9		8	D
6/20/25 11:22	6/16/25	VSTM	Verastem, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gagnon Robert E.	MA	D		1	S	-2	5.65	0		42	D
6/20/25 11:21	6/13/25	VSTM	Verastem, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Stuglik Brian M	MA	D		2	S	-31	3.54	-9		197	D
6/20/25 09:35	6/18/25	IMMX	Immix Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rachman Ilya M	CA	DO	CEO,CB	1	P	5	2.30	2	0	1,138	D
6/20/25 09:35	6/18/25	IMMX	Immix Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Morris Gabriel S	CA	DO	CFO	1	P	5	2.28	2	0	583	D
6/20/25 09:09	6/18/25	IMRX	Immuneering Corp	DE	Health	Drug	Pharmaceutical Preparations	Zeskind Benjamin J.	MA	DOT	P,CEO	1	P	50	2.39	21	1	3,198	D
6/18/25 21:28	6/16/25	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mott David M	MA	D		4	P	3,403	3.86	881	44	2,897	D
6/18/25 18:45	6/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Looker Benjamin	MI	O	GC	1	S	-7	1.15	-6		401	D
6/18/25 18:44	6/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Koenig Sheldon L.	MI	DO	P,CEO	1	S	-34	1.11	-30		1,541	D
6/18/25 18:44	6/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Halladay Benjamin	MI	O	CFO	2	S	-8	1.15	-7		482	D
6/18/25 18:26	6/16/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Robb Gary Charles	CA	O	Chief Bu	2	S	-398	72.89	-5		37	D
6/18/25 18:22	6/17/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kintz Samuel	CO	DO	P,CEO	5	S.m	-743	19.80	-38		985	I
6/18/25 18:04	6/17/25	ARVN	Arvinas, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cacace Angela M	CT	O	Chief Sc	1	S	-19	7.49	-3		154	D
6/18/25 18:02	6/17/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gallagher Kathleen P.	CA	O	Chief Pr	7	S.d	-855	23.64	-36		51	D
6/18/25 17:18	6/16/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Franchi Jean M.	MA	O	CFO	1	S	-105	52.26	-2		68	D
6/18/25 17:12	6/16/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Meisner Lara	MA	O	GC	2	M.d	251	7.94	32		0	D
6/18/25 17:12	6/16/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Meisner Lara	MA	O	GC	2	S.d	-251	7.94	-32	-100	0	D
6/18/25 17:12	6/16/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Lee Chan Henry	V8	O	SVP,GC	2	S	-292	260.02	-1	0	278	D
6/18/25 17:00	6/16/25	RGLS	Regulus Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Collier Kathryn J	CA	D		1	M.dm	60	9.50	6	11	63	D
6/18/25 16:57	6/16/25	XLO	Xilio Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Shannon James Samuel	MA	D		1	P.m	48	0.6869	70		70	D
6/18/25 16:56	6/16/25	XLO	Xilio Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Russo Rene	MA	DO	P,CEO	1	P	25	0.6801	36	15	281	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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