Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	Title	#f	T	TVal	Price	Qty	oc	Own	H
7/1/25 21:17	6/27/25	CRVS	Corvus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Thompson Peter A.	CA	DT		1	S.d	-4,892	4.16	-1,176		7,165	I
7/1/25 20:33	6/27/25	TRDA	Entrada Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Parmar Kush	CA	DT		1	S.m	-867	6.93	-125		4,283	I
7/1/25 20:32	6/27/25	TRDA	Entrada Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5Am Ventures V, L.P.	CA	T		1	S.m	-867	6.93	-125		4,283	M
7/1/25 19:48	6/27/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Viking Global Investors LP	CT	T		1	S	-154,000	44.00	-3,500		18,555	I
7/1/25 17:01	6/30/25	AKBA	Akebia Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ostrowski Erik	MA	O	SVP,CFO,	1	S	-152	3.67	-41		504	D
7/1/25 16:49	6/27/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Abi-Saab Walid	P7	O	Chief Me	1	S	-20	13.92	-1		150	D
7/1/25 16:42	6/27/25	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Flynn James E	NY	T		1	S	-13,663	18.46	-740		9,775	I
7/1/25 16:42	6/27/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hohl Benjamin	CO	O	CFO	4	S.d	-249	19.52	-13		23	D
7/1/25 16:37	6/30/25	CLYM	Climb Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Brennan Aoife	MA	DO	P,CEO	1	S.d	-25	1.22	-21		48	D
7/1/25 16:30	6/30/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Du Ying	MA	DO	Chairper	6	S.dm	-7,092	30.08	-236		526	D
7/1/25 16:30	6/27/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Balcom Alexandra	MA	O	CFO	1	S.d	-1,600	80.02	-20		62	D
7/1/25 16:22	6/30/25	ALXO	Alx Oncology Holdings Inc	DE	Health	Drug	Pharmaceutical Preparations	Pinto Shelly	CA	O	SVP,Fina	1	S	-1	0.4302	-2		89	D
6/30/25 17:51	6/26/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Valantine Hannah	CA	D		2	S.d	-379	42.12	-9		8	M
6/30/25 17:02	6/26/25	ZVRA	Zevra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Thompson Rahsaan	FL	OH	Chief Le	1	S	-221	9.21	-24		43	D
6/27/25 17:07	6/26/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Noci Darlene	MA	O	Chief De	3	S.d	-898	74.86	-12		48	D
6/27/25 17:05	6/25/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pelish Henry E.	MA	O	Chief Sc	2	S.dm	-879	79.88	-11		63	D
6/27/25 16:39	6/26/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	7	S.d	-22,745	295.39	-77		37	D
6/27/25 16:27	6/27/25	NATR	Natures Sunshine Products Inc	UT	Health	Drug	Pharmaceutical Preparations	Shanghai Fosun Pharmaceutical (Group) Co., Ltd.	F4	T		1	S	-32,714	11.46	-2,855		64	I
6/27/25 16:15	6/26/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Edmondson Frazor Titus III	MA	O	GC	3	S.d	-431	35.58	-12		39	D
6/27/25 16:15	6/25/25	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	Lee Ting-Chuan	CA	D		1	S	-1	0.5100	-3	0	1,429	D
6/27/25 16:15	6/25/25	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	Tsai Chun-Jung	CA	D		2	S.m	-22	0.5166	-43		1,402	D
6/27/25 16:15	6/26/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Chen Yajing	MA	O	CFO	4	S.d	-605	32.72	-18		27	D
6/26/25 20:00	6/24/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Shelton Jerrell	TN	DO	P,CEO	2	S.dm	-2,405	6.75	-356		937	D
6/26/25 20:00	6/24/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kharabi Darius	MA	O	CHIEF BU	2	S	-21	3.97	-5		67	D
6/26/25 20:00	6/24/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Mandalam Ramkumar	TN	D		3	S.dm	-208	7.03	-30		77	D
6/26/25 20:00	6/24/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Reumuth Mary	MA	O	CFO	2	S	-25	3.89	-6		66	D
6/26/25 20:00	6/24/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bazemore Todd	MA	O	SEE REMA	2	S	-29	3.89	-7		88	D
6/26/25 20:00	6/24/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Brazzell Romulus K	MA	O	SEE REMA	2	S	-35	3.90	-9		88	D
6/26/25 20:00	6/24/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Iwicki Mark T	MA	D		3	S	-134	3.84	-35		269	D
6/26/25 17:26	6/24/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Burns James William	MA	O	GC	1	S.d	-94	33.54	-3		29	D
6/26/25 17:25	6/24/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gheuens Sarah	MA	O	Chief Me	1	S.d	-98	33.54	-3		57	D
6/26/25 17:24	6/24/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jones Cecilia	MA	O	CFO	1	S.d	-60	33.54	-2		30	D
6/26/25 17:23	6/24/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Milanova Tsveta	MA	O	Chief Co	1	S.d	-93	33.54	-3		26	D
6/26/25 17:22	6/24/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Goff Brian	MA	DO	CEO	1	S.d	-627	33.54	-19		112	D
6/26/25 17:08	6/24/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McCormick Frank	CA	D		1	S	-4,423	44.23	-100		963	I
6/25/25 19:44	6/25/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Weinhoff Gregory M	X0	O	Chief Bu	3	S.d	-427	13.44	-32		122	D
6/25/25 19:43	6/24/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Hussain Iqbal J	X0	O	GC	3	S.dm	-252	14.01	-18		111	D
6/25/25 19:42	6/24/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Accardi Mario Alberto	X0	O	P,Orexin	1	S.d	-210	14.00	-15		216	D
6/25/25 18:52	6/23/25	OKUR	Onkure Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Saccomano Nicholas A	CO	DO	P,CEO	2	S.m	-3	2.89	-1		4	D
6/25/25 18:49	6/23/25	OKUR	Onkure Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Leverone Jason A.	CO	O	CFO	2	S.m	-10	2.89	-3		13	D
6/25/25 17:09	6/23/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Wang Lai	V8	O	Global H	3	S.m	-1,053	258.24	-4	0	1,769	D
6/25/25 17:08	6/23/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Wu Xiaobin	V8	O	P,COO	4	S.dm	-16,022	279.17	-57		1,262	D
6/25/25 17:08	6/24/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Wang Xiaodong	V8	DH	Chair, S	4	S.d	-30,975	243.35	-127		10,159	D
6/25/25 17:06	6/23/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Oyler John	V8	DO	CEO	3	S.m	-3,480	258.90	-13	0	54,270	D
6/25/25 17:01	6/23/25	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	Taiwan Carbon Nano Technology Corp	F5	T		1	S	0	0.00	-29		5,471	D
6/25/25 16:38	6/24/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mesa Nilda	MD	D		1	S	-187	289.99	-1		5	D
6/25/25 16:36	6/24/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Giltner Richard	MD	D		1	S.d	-879	289.60	-3		19	D
6/25/25 16:18	6/23/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Bonstein Sara	NJ	O	CFO	4	S.dm	-11,849	92.85	-128		113	D
6/24/25 21:01	6/20/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Venker Eric	NY	O	P,COO	4	S.dm	-14,417	11.09	-1,300		1,462	D
6/24/25 20:29	6/23/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Reardon Andrew	FL	O	CLO,Secr	3	S	-218	109.16	-2		33	D
6/24/25 18:33	6/23/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Piscitelli Dominic	CA	O	CFO	4	S.m	-416	10.41	-40		104	D
6/24/25 18:08	6/20/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Springhorn Jeremy P.	P7	D		1	S	-31	14.45	-2		38	D
6/24/25 18:03	6/20/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Post Leonard E	P7	D		1	S	-31	14.45	-2		30	D
6/24/25 17:53	6/20/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Kaye Jack	P7	D		1	S	-31	14.45	-2		20	D
6/24/25 17:50	6/20/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Jacques Rachelle Suzanne	P7	D		1	S	-31	14.45	-2		28	D
6/24/25 17:45	6/20/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Gut Robert	P7	D		1	S	-48	14.45	-3		57	D
6/24/25 17:42	6/20/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Balachandran Madhavan	P7	D		1	S	-31	14.45	-2		38	D
6/24/25 17:36	6/20/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lyssikatos Joseph P	CO	O	CHIEF SC	5	S.m	-730	19.47	-38		998	I
6/24/25 17:34	6/20/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Meek David D.	P7	D		1	S	-31	14.45	-2		34	D
6/24/25 16:39	6/20/25	VSTM	Verastem, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Paterson Dan	MA	DO	P,CEO	4	S	-576	7.42	-78		462	D
6/24/25 16:37	6/20/25	VSTM	Verastem, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Calkins Daniel	MA	O	CFO	2	S.m	-112	7.32	-15		114	D
6/24/25 16:08	6/24/25	ARVN	Arvinas, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Saik Andrew	CT	O	CFO	1	S	-43	7.61	-6		164	D
6/24/25 16:00	6/20/25	MRUS	Merus N.V.	P7	Health	Drug	Pharmaceutical Preparations	Silverman Peter B.	P7	O	COO,GC	1	S.d	-1,794	52.76	-34	-100	0	D
6/23/25 19:42	6/20/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Murdock Hunter R.	NY	O	GC	2	S.dm	-3,647	101.28	-36	-100	0	D
6/23/25 16:10	6/20/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Lis William	MA	D		1	S	-493	35.67	-14		35	D
6/23/25 13:50	6/20/25	RARE	Ultragenyx Pharmaceutical Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sanders Corazon (Corsee) D.	CA	D		1	S	-90	37.39	-2		15	D
6/23/25 11:35	6/18/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Ramaswamy Vivek	DC	T		3	S.m	-31,669	11.35	-2,789		52,532	D
6/20/25 21:09	6/18/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cheng Andrew	CA	DO	P,CEO	4	S	-4,709	45.08	-104		624	D
6/20/25 21:08	6/18/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gangloff Scott A.	CA	O	CTO	1	S	-47	54.84	-1		23	D
6/20/25 21:08	6/20/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lamy Patrick	CA	O	SVP,Comm	6	S.d	-947	47.84	-20		33	D
6/20/25 21:07	6/18/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rolph Timothy	CA	O	Chief Sc	6	S.dm	-3,257	49.36	-66		170	D
6/20/25 21:07	6/18/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	White William Richard	CA	O	CFO	2	S	-241	54.31	-4		59	D
6/20/25 21:07	6/18/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yale Catriona	CA	O	Chief De	5	S.d	-1,520	45.37	-34		95	D
6/20/25 21:06	6/18/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Young Jonathan	CA	O	COO	2	S	-214	54.31	-4		258	D
6/20/25 20:58	6/20/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Saha Saurabh	X0	DO	CEO	3	S.dm	-2,076	12.58	-165		259	D
6/20/25 20:24	6/16/25	IGMS	Igm Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Weber Steven	CA	O	Principa	2	S	-3	1.14	-2		27	D
6/20/25 20:23	6/16/25	IGMS	Igm Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tahir Misbah	CA	O	CFO	1	S	-2	1.20	-2		179	D
6/20/25 20:20	6/16/25	IGMS	Igm Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Harler Mary Beth	CA	DO	CEO	1	S	-2	1.20	-2	0	338	D
6/20/25 20:19	6/16/25	IGMS	Igm Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Decker Lisa Lynn	CA	O	Chief Bu	1	S	-1	1.20	-1		73	D
6/20/25 19:43	6/16/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Potts Jeannette		O	GC	1	S	-71	15.14	-5		115	D
6/20/25 18:38	6/18/25	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Karas Eric	CA	O	Chief Co	1	S.d	-240	16.00	-15		8	D
6/20/25 17:42	6/17/25	TYRA	Tyra Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kaplan Gilla	CA	D		2	S.m	-628	10.23	-61		38	D
6/20/25 16:32	6/18/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Welgus Howard G.	CA	D		3	S	-433	14.37	-30		122	D
6/20/25 16:20	6/20/25	CLYM	Climb Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pimblett Emily	MA	O	SVP,Fina	1	S.d	-2	1.24	-1		19	D
6/20/25 16:08	6/18/25	NKTX	Nkarta, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hastings Paul J	CA	DO	CEO	1	S	-3	1.79	-2		320	D
6/20/25 16:07	6/18/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Fenton Dennis M	CA	D		1	S	-72	23.97	-3		5	D
6/20/25 16:06	6/18/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Renton Hollings	CA	D		1	S	-72	23.97	-3		5	D
6/20/25 11:22	6/16/25	VSTM	Verastem, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gagnon Robert E.	MA	D		1	S	-2	5.65	0		42	D
6/20/25 11:21	6/13/25	VSTM	Verastem, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Stuglik Brian M	MA	D		2	S	-31	3.54	-9		197	D
6/18/25 18:45	6/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Looker Benjamin	MI	O	GC	1	S	-7	1.15	-6		401	D
6/18/25 18:44	6/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Koenig Sheldon L.	MI	DO	P,CEO	1	S	-34	1.11	-30		1,541	D
6/18/25 18:44	6/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Halladay Benjamin	MI	O	CFO	2	S	-8	1.15	-7		482	D
6/18/25 18:26	6/16/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Robb Gary Charles	CA	O	Chief Bu	2	S	-398	72.89	-5		37	D
6/18/25 18:22	6/17/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kintz Samuel	CO	DO	P,CEO	5	S.m	-743	19.80	-38		985	I
6/18/25 18:04	6/17/25	ARVN	Arvinas, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cacace Angela M	CT	O	Chief Sc	1	S	-19	7.49	-3		154	D
6/18/25 18:02	6/17/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gallagher Kathleen P.	CA	O	Chief Pr	4	S.d	-572	30.87	-19		51	D
6/18/25 17:18	6/16/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Franchi Jean M.	MA	O	CFO	1	S	-105	52.26	-2		68	D
6/18/25 17:12	6/16/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Meisner Lara	MA	O	GC	1	S.d	-165	10.43	-16	-100	0	D
6/18/25 17:12	6/16/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Lee Chan Henry	V8	O	SVP,GC	2	S	-292	260.02	-1	0	278	D
6/18/25 16:50	6/16/25	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	Kling Douglas F	P7	O	COO	3	S.d	-1,929	6.43	-300		44	D
6/18/25 16:39	6/16/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Tessari Eben	X0	O	COO	4	S.dm	-3,212	28.64	-112		77	D
6/18/25 16:31	6/16/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Fisher Andrew	X0	O	GC	3	S.d	-1,842	9.90	-186		360	D
6/18/25 16:16	6/16/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Lewis William	NJ	DO	Chair,CE	7	S.dm	-19,212	88.57	-217		619	M
6/18/25 16:15	6/16/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Adsett Roger	NJ	O	COO	3	S.m	-1,823	83.03	-22		141	D
6/18/25 16:15	6/16/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bredt David	MA	O	Chief Sc	3	S	-256	10.04	-26		461	D
6/18/25 16:11	6/16/25	AMRX	Amneal Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Patel Gautam	NJ	D		3	S.m	-1,283	8.02	-160		1,720	D
6/18/25 08:49	6/16/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Watson David O.	MA	O	GC	1	S	-94	18.77	-5		214	D
6/17/25 19:55	6/13/25	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Wilson Troy Edward	CA	D		1	S	-37	3.40	-11		44	D
6/17/25 19:49	6/13/25	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Senderowicz Adrian	CA	D		1	S	-92	3.40	-27		27	D
6/17/25 19:46	6/13/25	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Moyes Jay M	CA	D		1	S	-75	3.40	-22		53	D
6/17/25 19:43	6/13/25	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dorval Allison	CA	D		2	S.d	-53	3.57	-15		89	D
6/17/25 19:41	6/13/25	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cesano Alessandra	CA	D		1	S	-41	3.40	-12		69	D
6/17/25 16:31	6/16/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Porter James Richard	MA	DO	P,CEO	3	S.d	-5,818	71.82	-81		249	D
6/17/25 16:27	6/17/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Malik Fady Ibraham	CA	O	EVP Rese	6	S.d	-412	34.35	-12		141	D
6/17/25 16:11	6/13/25	CTMX	Cytomx Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ogden Christopher	CA	O	CFO	1	S.dm	-33	2.72	-12		226	D
6/17/25 16:10	6/16/25	CTMX	Cytomx Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Belvin Marcia	CA	O	SVP,Chie	1	S.d	-37	2.69	-14		272	D
6/17/25 16:09	6/16/25	CTMX	Cytomx Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McCarthy Sean A.	CA	DO	CEO	1	S.d	-149	2.69	-56		1,183	D
6/16/25 21:10	6/13/25	VNDA	Vanda Pharmaceuticals Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mitchell Stephen Ray	DC	D		1	S	-32	4.59	-7		97	D
6/16/25 19:35	6/16/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	Montgomery Alan Bruce	CA	D		1	S.d	-20	9.22	-2		21	D
6/16/25 19:31	6/16/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	Gustafson Kurt A	CA	D		1	S.d	-28	9.22	-3		20	D
6/16/25 19:30	6/16/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	Gorman Kevin Charles	CA	D		1	S.d	-29	9.22	-3		19	D
6/16/25 19:26	6/16/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	Feigal Ellen	CA	D		1	S.d	-28	9.22	-3		19	D
6/16/25 19:22	6/16/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	Ranieri Richard J	CA	D		1	S.d	-28	9.22	-3		19	D
6/16/25 17:47	6/13/25	TGTX	Tg Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Echelard Yann	NC	D		1	S	-369	36.94	-10		229	D
6/16/25 17:24	6/13/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Cook Meredith	MN	O	SVP,GC,S	3	S	-77	64.18	-1		80	D
6/16/25 17:19	6/16/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Blum Robert I	CA	DO	P,CEO	5	S	-868	34.74	-25		427	D
6/16/25 16:56	6/12/25	ETON	Eton Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Krempa David	IL	O	Chief Bu	1	S.m	-504	14.83	-34		613	D
6/16/25 16:48	6/12/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Betz Stephen F.	CA	O	Chief Sc	1	S.d	-3,142	32.23	-97		100	D
6/16/25 16:42	6/13/25	EOLS	Evolus, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Moatazedi David	CA	DO	See Rema	2	S.m	-1,439	10.01	-144		493	D
6/16/25 16:03	6/12/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	Kalif Eliyahu Sharon	L3	O	EVP,CFO	1	S	-952	17.08	-56		403	D
6/16/25 16:03	6/13/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rodman David Malcom	PA	O	Chief Me	4	S.d	-1,384	15.40	-90		117	D
6/16/25 15:40	5/28/25	ANTX	An2 Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Leonard Braden Michael	IN	T		2	S.m	-3,090	1.13	-2,732		3,217	I
6/13/25 20:00	6/13/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	Verdine Gregory L.	MA	D		1	S	-209	6.95	-30		283	D
6/13/25 19:57	6/13/25	LTRN	Lantern Pharma Inc.	TX	Health	Drug	Pharmaceutical Preparations	Fletcher Aaron G.L.	TX	T		3	S.m	-500	3.17	-158		1,178	I
6/13/25 19:50	6/13/25	LTRN	Lantern Pharma Inc.	TX	Health	Drug	Pharmaceutical Preparations	Kreis Leslie W.	TX	T		3	S.m	-500	3.17	-158		1,178	I
6/13/25 16:31	6/11/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Hahn Mark W	X0	O	CFO	4	S.dm	-14,417	9.76	-1,477		13,466	D
6/13/25 16:30	6/11/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Zaccardelli David	X0	DO	P,CEO	4	S.dm	-14,418	9.76	-1,477		14,377	D
6/13/25 16:18	6/11/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fairey William	CA	D		1	S	-155	48.42	-3		3	D
6/12/25 20:42	6/10/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Swisher Daniel N Jr	CA	D		3	S.d	-468	70.96	-7	-100	0	D
6/12/25 20:41	6/10/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Guyer William	CA	O	Chief De	3	S.d	-4,366	73.60	-59		5	D
6/12/25 18:18	6/11/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Flanagan W. Michael	CA	O	Chief Sc	1	S.d	-658	32.88	-20		80	D
6/12/25 17:51	6/11/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Ball Titus B.	V8	O	Principa	1	S	-35	258.36	0	0	74	D
6/12/25 17:00	6/10/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sundaram Preethi	FL	O	Chief St	1	S.m	-104	26.41	-4		41	D
6/12/25 16:50	6/10/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	German Christopher Paul	MA	O	Corporat	1	S.d	-139	67.19	-2		2	D
6/12/25 16:21	6/10/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Flammer Martina M.D.	NJ	O	Chief Me	4	S.dm	-5,693	82.84	-69		90	D
6/12/25 16:20	6/10/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Schaeffer Orlov S Nicole	NJ	O	Chief Pe	3	S.dm	-13,197	90.79	-145		119	D
6/11/25 18:25	6/9/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Patel Anish	CO	O	COO	3	S	-378	18.92	-20		317	I
6/11/25 17:40	6/9/25	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	Molina Arturo Md	CA	O	Chief Me	1	S.dm	-1,125	56.27	-20		84	D
6/11/25 17:35	6/9/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Quart Barry D	X0	D		1	S.dm	-833	30.35	-27		13	D
6/11/25 17:13	6/9/25	AKBA	Akebia Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Malabre Richard C	MA	O	SVP,Chie	2	S.d	-107	3.78	-28		267	D
6/11/25 17:04	6/9/25	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	Freund John Gordon	MA	D		1	S.d	-202	30.62	-7		114	D
6/11/25 16:15	6/9/25	HROW	Harrow, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T		5	S.am	-1,758	29.30	-60		3,960	I
6/11/25 09:14	6/9/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Schoenberg Mark	NJ	O	Chief Me	1	S.d	-38	7.37	-5		153	D
6/10/25 20:07	6/10/25	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	Binder Steven B.	CT	D		3	S.d	-685	4.38	-156		1,007	D
6/10/25 19:28	6/10/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Zecchini Edward J	TN	O	Chief Di	1	S.d	-353	6.85	-52		90	D
6/10/25 19:00	6/9/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jacobson Mark L.	NY	O	COO	2	S.dm	-6,994	106.49	-66		6	D
6/10/25 17:00	6/9/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Palleiko Benjamin L	MA	DO	CEO	3	S.d	-268	12.77	-21		315	D
6/10/25 17:00	6/6/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McEnany Patrick J	FL	DH	Chairman	1	S.m	-5,217	26.09	-200		4,282	D
6/10/25 16:45	6/6/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cramer Pamela J.	MA	O	CHRO	3	S.d	-2,185	62.74	-35		19	D
6/10/25 16:39	6/9/25	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	Nichols Christian Todd	MA	O	SVP,Chie	1	S.m	-210	31.52	-7		86	D
6/10/25 16:30	6/9/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Edgemond James	MD	O	CFO,TREA	2	S.d	-7,814	325.60	-24		8	D
6/9/25 20:49	6/6/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Savage William Jacob	MA	O	Chief Me	3	S	-589	50.05	-12		66	D
6/6/25 18:04	6/6/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Vazzano Joseph Walter	OH	O	CFO	1	S	-120	6.76	-18		491	D
6/6/25 18:00	6/6/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Seshadri Vishwas	OH	DO	CEO	1	S	-343	6.76	-51		1,304	D
6/6/25 17:58	6/5/25	XENE	Xenon Pharmaceuticals Inc.	A1	Health	Drug	Pharmaceutical Preparations	Gannon Steven	A1	D		1	S.d	0	30.33	0	0	7	D
6/6/25 17:56	6/6/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	O'Malley Brendan M.	OH	O	SVP,GC	1	S	-71	6.76	-10		378	D
6/6/25 16:53	6/5/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Smith Michael Alexander	NJ	O	GC	4	S.m	-2,401	69.66	-34		92	D
6/6/25 16:47	6/5/25	KRON	Kronos Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Knobelman Deborah	MA	O	P,Interi	1	S	-22	0.8678	-25		139	D
6/6/25 16:20	6/4/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Skorpios Trust	G4	T		1	S	-30,600	10.20	-3,000		3,906	I
6/6/25 16:07	6/5/25	DYN	Dyne Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cox John	MA	DO	CEO,P	1	S	-54	13.35	-4		174	D
6/6/25 16:05	6/5/25	DYN	Dyne Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kerr Douglas	MA	O	Chief Me	1	S	-18	13.35	-1		93	D
6/6/25 16:03	6/5/25	DYN	Dyne Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Friedl-Naderer Johanna	MA	O	Chief Co	1	S	-2	13.35	0	0	96	D
6/5/25 19:25	3/26/25	NTHI	Neonc Technologies Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chiang Ming-Fu (Alan)	CA	D		2	S.ad	-2,868	24.85	-115		2,180	M
6/5/25 19:20	3/26/25	NTHI	Neonc Technologies Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Walters Patrick	CA	O	COO	2	S.ad	-589	24.85	-24		876	I
6/5/25 19:15	3/26/25	NTHI	Neonc Technologies Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Garnett Keithly	CA	DO	CFO	2	S.ad	-329	24.85	-13		321	I
6/5/25 19:10	3/26/25	NTHI	Neonc Technologies Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Heshmatpour Amir F	CA	D		2	S.ad	-1,912	24.85	-77		6,802	I
6/5/25 19:05	3/26/25	NTHI	Neonc Technologies Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chen Thomas C	CA	DOT	CEO	2	S.ad	-1,950	24.85	-78		4,843	I
6/5/25 18:01	6/4/25	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Brege Laura	CA	D		1	S	-315	21.78	-14		15	D
6/5/25 17:40	6/4/25	PCRX	Pacira Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Riker Lauren	CA	O	SVP,Fina	1	S	-146	26.21	-6		60	D
6/5/25 17:37	6/4/25	PCRX	Pacira Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Williams Kristen	CA	O	Chief Ad	1	S	-377	26.24	-14		162	D
6/5/25 17:15	6/3/25	ETON	Eton Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Brynjelsen Sean	IL	DOT	P,CEO	1	S.m	-3,593	17.11	-210		2,874	D
6/5/25 17:08	6/3/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	Shields Matthew	L3	O	EVP,Glob	1	S.d	-106	17.02	-6		10	D
6/5/25 16:50	6/3/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Megna Michael R	X0	O	CHIEF AC	2	S.d	-908	27.64	-33		33	D
6/5/25 16:46	6/3/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Moat Ross	X0	O	CHIEF CO	4	S.dm	-3,720	25.97	-143		9	D
6/5/25 16:42	6/5/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Kaye Edward M. Md	CA	D		1	S	-117	32.10	-4		30	D
6/5/25 16:38	6/3/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Ragosa Mark	X0	O	CFO	2	S.dm	-2,874	26.94	-107		27	D
6/5/25 16:38	6/5/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Callos Andrew	CA	O	EVP,Chie	3	S	-527	33.93	-16		65	D
6/5/25 16:22	6/3/25	BPMC	Blueprint Medicines Corp	DE	Health	Drug	Pharmaceutical Preparations	Carter Percy H.	MA	O	Chief Sc	1	S	-340	127.88	-3		54	D
6/5/25 16:20	6/4/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Schundler Russell	NC	O	GC	3	S.d	-240	15.63	-15		597	D
6/5/25 16:20	6/4/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Moomaw Scott	NC	O	Chief Co	3	S.d	-169	15.87	-11		225	D
6/5/25 16:19	6/4/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Saggar Rajeev	NC	O	Chief Me	3	S.d	-213	15.46	-14		273	D
6/5/25 16:18	6/4/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Jeffs Roger	NC	DO	CEO	2	S.d	-711	15.90	-45		2,633	D
6/5/25 16:18	6/4/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Kaseta Michael	NC	O	CFO,COO	3	S.d	-378	15.78	-24		412	D
6/5/25 16:16	6/3/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McGirr David W J	MA	D		2	S.dm	-4,719	65.83	-72		101	D
6/5/25 16:16	6/3/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Meeker David P	MA	DO	P,CEO	1	S.d	-2,837	65.05	-44		202	D
6/5/25 16:15	6/4/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Adair Jason	NC	O	Chief Bu	4	S.d	-100	15.77	-6		194	D
6/4/25 20:41	6/2/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Belanoff Joseph K	CA	DO	CEO	2	S	-6,230	77.88	-80		2,942	I
6/4/25 20:34	6/2/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Lyon Joseph Douglas	CA	O	See Rema	2	S.d	-1,063	74.08	-14		10	D
6/4/25 20:33	6/2/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Maduck Sean	CA	O	See Rema	2	S.dm	-4,424	74.47	-59		117	D
6/4/25 20:30	6/2/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ticho Barry	MA	O	Chief Me	2	S.m	-349	10.02	-35		34	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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