Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	Title	#f	T	TVal	Price	Qty	oc	Own	H
10/16/25 18:00	10/14/25	BGMS	Bio Green Med Solution, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ong Yee Lung	N8	T		1	S	-815	6.00	-136		269	D
10/16/25 17:05	9/2/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Blum Robert I	CA	DO	P,CEO	6	S	-1,442	48.08	-30		392	D
10/16/25 16:41	10/15/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cohlhepp Ryan	MA	DO	P,COO	2	S.dm	-1,139	18.08	-63		203	D
10/16/25 16:35	10/14/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Tessari Eben	X0	O	COO	7	S.dm	-11,865	34.97	-339		50	D
10/16/25 16:30	10/15/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	15	S.dm	-49,140	423.62	-116		644	D
10/16/25 16:30	10/15/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bredt David	MA	O	Chief Sc	3	S	-552	21.66	-26		427	D
10/16/25 16:30	9/4/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ceesay Abraham	MA	DO	CEO	3	S	-2,357	26.28	-90		722	D
10/16/25 16:21	10/7/25	EBS	Emergent Biosolutions Inc.	DE	Health	Drug	Pharmaceutical Preparations	Glessner Coleen	MD	O	EVP,Qual	1	S	-306	10.00	-31		144	D
10/16/25 16:15	10/16/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Seshadri Vishwas	OH	DO	CEO	2	S.m	-236	5.31	-45		1,190	D
10/16/25 16:13	8/15/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Hussain Iqbal J	X0	O	GC	4	S.dm	-1,209	20.85	-58		111	D
10/16/25 16:01	10/14/25	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Militello John	NJ	O	See Rema	3	S.m	-139	3.76	-37		67	D
10/15/25 20:56	10/13/25	LVTX	Lava Therapeutics Nv	P7	Health	Drug	Pharmaceutical Preparations	Cooperatieve Gilde Healthcare IV U.A.	P7	T		2	S.m	-917	1.52	-602		5,294	D
10/15/25 20:12	10/10/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dunlop A. Sinclair	MA	D		3	S	-2,153	23.08	-93		223	M
10/15/25 20:07	9/12/25	BYSI	Beyondspring Inc.		Health	Drug	Pharmaceutical Preparations	Decheng Capital China Life Sciences Usd Fund Iii, L.P.	CA	T		16	S.m	-1,792	2.48	-723		4,488	I
10/15/25 19:04	10/13/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Levy Adam Scott	PA	O	CFO,Secr	2	S.m	-1,529	18.11	-84		133	D
10/15/25 19:04	10/13/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Congleton Jon	PA	DO	CEO	1	S	-644	42.67	-15		831	D
10/15/25 19:04	10/15/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rodman David Malcom	PA	O	Chief Me	3	S.d	-1,002	30.28	-33		93	D
10/15/25 18:47	10/15/25	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	Hopkinson Craig C.	MA	O	EVP R,D,	1	S.d	-284	31.53	-9		74	D
10/15/25 18:33	10/10/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Booth Bruce	MA	D		3	S.m	-9,793	30.30	-323		3,615	I
10/15/25 18:31	10/10/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Swisher Daniel N Jr	CA	D		3	S.d	-511	77.43	-7	-100	0	D
10/15/25 18:00	10/13/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mazumdar Claire	MA	DO	CEO	1	S.dm	-467	18.88	-25		310	D
10/15/25 16:36	10/13/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Schundler Russell	NC	O	GC	2	S.d	-214	24.08	-9		595	D
10/15/25 16:34	10/13/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Kaseta Michael	NC	O	CFO,COO	4	S.d	-1,429	22.77	-63		376	D
10/15/25 16:34	10/13/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Moomaw Scott	NC	O	Chief Co	2	S.d	-2,138	28.29	-76		155	D
10/15/25 16:33	10/13/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Saggar Rajeev	NC	O	Chief Me	3	S.d	-719	25.80	-28		269	D
10/15/25 16:32	10/13/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Boyle Dana	NC	O	Chief Ac	3	S	-58	22.47	-3		187	D
10/15/25 16:32	10/6/25	SPRB	Spruce Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Parkman Healthcare Partners LLC	CT	T		2	S	-10	19.14	-1		1	I
10/15/25 16:31	9/2/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Jeffs Roger	NC	DO	CEO	4	S.dm	-13,848	106.18	-130		2,752	D
10/15/25 16:31	10/13/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Adair Jason	NC	O	Chief Bu	3	S.dm	-834	27.22	-31		193	D
10/15/25 16:30	10/13/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Balcom Alexandra	MA	O	CFO	3	S.dm	-7,550	86.20	-88		62	D
10/15/25 16:30	10/13/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Benkowitz Michael	MD	O	P,COO	7	S.dm	-63,788	421.39	-151		3	I
10/15/25 16:30	8/7/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pelish Henry E.	MA	O	Chief Sc	3	S.dm	-1,600	82.92	-19		66	D
10/15/25 16:30	10/13/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Krepp Sarah	NC	O	Chief Hu	2	S	-46	24.03	-2		143	D
10/15/25 13:24	10/15/25	KROS	Keros Therapeutics, Inc.		Health	Drug	Pharmaceutical Preparations	Adar1 Capital Management, LLC	TX	T		1	S	-95,659	17.75	-5,389	-100	0	I
10/14/25 21:00	10/9/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Venker Eric	X0	O	P,Immuno	5	S.dm	-40,678	15.06	-2,702		1,654	D
10/14/25 20:11	10/10/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cheng Andrew	CA	DO	P,CEO	3	S.dm	-4,452	48.49	-92		526	D
10/14/25 19:49	10/13/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Cook Meredith	MN	O	SVP,GC,S	3	S	-111	92.46	-1		76	D
10/14/25 18:00	10/10/25	BGMS	Bio Green Med Solution, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fitters Diversified Berhad	N8	T		2	S	-1,022	5.28	-193		557	D
10/14/25 16:31	10/9/25	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	Bunn Paul A.	MA	D		1	S	-75	9.06	-8		8	D
10/14/25 16:05	10/9/25	CVKD	Cadrenal Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Szot Matthew K	FL	O	CFO	5	S.m	-278	14.03	-20		31	D
10/14/25 16:05	10/9/25	CVKD	Cadrenal Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pham Quang X	FL	DOT	CEO,CB	5	S.m	-278	14.05	-20		413	D
10/14/25 16:01	10/10/25	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	Waddill William D.	CA	D		3	S.d	-1,473	73.67	-20		9	D
10/14/25 16:00	7/24/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	Lilly Endowment Inc	IN	T		13	S	-1,208,375	814.46	-1,484		95,737	D
10/14/25 13:16	8/18/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	Moreadith Randall	AL	O	Chief Sc	8	S.dm	-534	6.32	-85	-100	0	D
10/14/25 12:15	10/13/25	RARE	Ultragenyx Pharmaceutical Inc.	DE	Health	Drug	Pharmaceutical Preparations	Horn Howard	CA	O	CFO	1	S	-250	31.51	-8		98	D
10/10/25 19:17	10/10/25	ZVRA	Zevra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McFarlane Neil F.	FL	DO	P,CEO	1	S.d	-211	10.82	-20		222	D
10/10/25 18:17	9/12/25	BGMS	Bio Green Med Solution, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kua Khai Loon	N8	T		2	S.m	-400	6.04	-66		385	D
10/10/25 17:40	9/4/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kumar Neil	CA	DO	CEO	4	S.m	-13,503	50.73	-266		5,857	I
10/10/25 17:33	10/9/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Khattar Jack A.	MD	DO	P,CEO	13	S.dm	-18,547	45.67	-406		2,212	D
10/10/25 17:23	10/9/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Raben David	MA	O	Chief Me	1	S.d	-406	18.45	-22		35	D
10/10/25 17:22	10/9/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hyep Ivan	MA	O	CFO	2	S.dm	-670	18.21	-37		145	D
10/10/25 16:56	10/8/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Lee Chan Henry	V8	O	SVP,GC	4	S.d	-10,586	324.61	-33		266	D
10/10/25 16:30	10/8/25	ALZN	Alzamend Neuro, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ault Milton C III	NV	D		10	S.dm	-2,212	2.44	-905		124	I
10/10/25 16:21	10/9/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Newhall Charles W III	MD	D		4	S	-1,539	49.65	-31		134	D
10/10/25 16:18	10/8/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Scadden David	MA	D		3	S.d	-24	40.33	-1		18	D
10/10/25 16:12	10/8/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kaye Edward M. Md	MA	D		7	S.dm	-4,394	27.18	-162		177	D
10/10/25 16:01	10/8/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	Anderman Todd	MA	O	GC	1	S	-137	12.34	-11		88	D
10/9/25 18:58	9/8/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rolph Timothy	CA	O	Chief Sc	4	S.d	-1,768	46.47	-38		167	D
10/9/25 17:51	10/7/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Guyer William	CA	O	Chief De	5	S.dm	-6,081	76.10	-80		5	D
10/9/25 17:21	10/7/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Patel Anish	CO	O	COO	3	S	-391	19.53	-20		290	I
10/9/25 16:22	8/19/25	HOOK	Hookipa Pharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	Peters Malte	NY	DO	CEO	2	S	-48	0.8745	-54		80	D
10/9/25 16:07	10/7/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bitterman Kevin	MA	D		7	S.m	-11,618	65.68	-177		1,148	I
10/9/25 13:37	10/8/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Degnan Chris	NJ	O	CFO	1	S.d	-37	16.85	-2		2	D
10/8/25 21:08	10/6/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tabuteau Herriot	NY	DOT	CEO	2	S.dm	-12,780	118.04	-108		7,352	D
10/8/25 19:48	10/1/25	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hunter Heather	MI	O	SVP,COO	1	S	-3	1.19	-3		135	D
10/8/25 19:08	10/6/25	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jarrett Jennifer	CA	O	COO	1	S.dm	-750	14.92	-50		214	D
10/8/25 18:37	10/6/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Swayze Eric	CA	O	EVP Rese	3	S.dm	-2,819	62.52	-45		37	D
10/8/25 18:37	10/6/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	O'Neil Patrick R.	CA	O	EVP CLO,	6	S.dm	-13,812	63.94	-216		57	D
10/8/25 18:36	10/6/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Monia Brett P	CA	DO	CEO	3	S.d	-12,434	60.16	-207		180	D
10/8/25 18:36	10/6/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Baroldi Joseph	CA	O	EVP,Chie	5	S.d	-3,837	62.27	-62		35	D
10/8/25 17:37	10/6/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Piscitelli Dominic	CA	O	CFO	1	S.d	-160	14.52	-11		48	D
10/8/25 17:35	10/6/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chacko Jacob	CA	DO	P,CEO	3	S.m	-2,865	11.46	-250		656	D
10/8/25 16:16	10/7/25	CARM	Carisma Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Klichinsky Michael	PA	O	Chief Sc	2	S.dm	-139	0.2565	-541	-100	0	D
10/8/25 16:10	8/5/25	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	Taiwan Carbon Nano Technology Corp	F5	T		5	S.m	-167	2.94	-57		1,080	D
10/7/25 17:08	9/9/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Malik Fady Ibraham	CA	O	EVP Rese	6	S.d	-547	45.54	-12		141	D
10/7/25 16:26	10/3/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Allan Jonathan	MA	O	GC,Corp	4	S.dm	-932	19.61	-48		24	D
10/7/25 16:11	10/3/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mosbrooker Eric	CA	O	Chief Co	3	S.d	-6,370	44.26	-144		55	D
10/6/25 17:13	10/2/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	Kaiser Peter	MA	O	Chief De	2	S	-143	11.27	-13		204	D
10/6/25 17:10	10/2/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	Heier Jeffrey S.	MA	O	Chief Sc	2	S	-153	11.27	-14		260	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Lee Kevin	X0	DO	CEO	1	S.m	-46	8.41	-5		475	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Skynner Michael	X0	O	CTO	1	S.m	-15	8.41	-2		118	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Milnes Alistair	X0	O	COO	1	S.m	-18	8.40	-2		93	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Hannay Michael Charles Ferguson	X0	O	CHIEF PR	1	S.m	-6	8.40	-1		53	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Young Alethia	X0	O	CFO	1	S	-4	8.51	0		45	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Thompson Travis Alvin	X0	O	Chief Ac	1	S.m	-3	8.40	0		31	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Swanton Robert Charles	X0	D		1	S	-1	8.55	0		15	D
10/6/25 15:15	10/2/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Edwards Larry Todd	CA	O	See Rema	1	S	-90	20.04	-5		179	D
10/3/25 21:58	10/2/25	ELTP	Elite Pharmaceuticals Inc /Nv/	NJ	Health	Drug	Pharmaceutical Preparations	Plassche Douglas	NJ	O	EVP Oper	1	S	-499	0.6240	-800		3,500	D
10/3/25 21:27	9/2/25	JAZZ	Jazz Pharmaceuticals Plc	L2	Health	Drug	Pharmaceutical Preparations	Cozadd Bruce C	L2	D		3	S.m	-1,638	131.08	-13		436	D
10/3/25 18:15	10/1/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hamilton James C	CA	O	Chief Me	4	S.m	-1,725	28.75	-60		262	D
10/3/25 17:24	10/1/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Belanoff Joseph K	CA	DO	CEO	4	S	-9,011	74.71	-121		2,901	I
10/3/25 17:17	10/1/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Lyon Joseph Douglas	CA	O	See Rema	4	S.dm	-1,468	73.75	-20		10	D
10/3/25 17:15	10/1/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Maduck Sean	CA	O	See Rema	4	S.dm	-5,836	73.14	-80		118	D
10/3/25 17:14	10/2/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Poulton Jeffrey V.	MA	O	EVP,CFO	2	S	-2,758	452.50	-6		54	D
10/3/25 17:14	10/2/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Greenstreet Yvonne	MA	DO	CEO	2	S	-7,197	452.58	-16		66	D
10/3/25 17:14	10/2/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Tanguler Tolga	MA	O	EVP,Chie	3	S	-2,826	450.28	-6		29	D
10/3/25 17:13	10/2/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Fitzgerald Kevin Joseph	MA	O	CSO,EVP,	2	S	-1,736	452.49	-4		26	D
10/3/25 17:12	10/2/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Garg Pushkal	MA	O	EVP Chie	2	S.m	-3,992	453.10	-9		21	D
10/3/25 17:02	10/1/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Watanabe Todd	CA	DO	See Rema	3	S.m	-1,228	18.41	-67		1,135	D
10/3/25 17:01	10/1/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Welgus Howard G.	CA	D		3	S.d	-489	16.29	-30		100	D
10/3/25 16:56	9/3/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Abate Kristin	MA	O	Chief Ac	4	S	-3	5.45	-1		10	D
10/3/25 16:45	10/1/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Kozarich John W	FL	D		3	S	-221	157.86	-1		46	D
10/3/25 16:41	9/2/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pizzuti Dana	CA	O	Chief Me	4	S.d	-1,472	31.66	-46		96	D
10/3/25 16:30	9/2/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Young Jonathan	CA	O	COO	4	S.d	-1,796	47.14	-38		257	D
10/3/25 16:25	10/1/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ticho Barry	MA	O	Chief Me	4	S	-345	18.98	-18		24	D
10/3/25 16:20	10/2/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Chen Yajing	MA	O	CFO	3	S.d	-206	34.37	-6		17	D
10/3/25 16:07	10/2/25	VRTX	Vertex Pharmaceuticals Inc / Ma	MA	Health	Drug	Pharmaceutical Preparations	Biller Jonathan	MA	O	EVP,GC	1	S	-281	404.21	-1		16	D
10/2/25 19:36	10/1/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Wender Joseph H	CA	D		3	S.m	-4,325	59.41	-73		109	I
10/2/25 19:24	10/1/25	TERN	Terns Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kuriakose Emil	CA	O	Chief Me	1	S	-7	7.85	-1		52	D
10/2/25 17:04	10/1/25	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Petersen Floyd F.	CA	D		3	S	-40	26.34	-2		77	D
10/2/25 16:47	9/30/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Baker Bros. Advisors LP	NY	H	Former 1	1	S.m	-1,057	1.45	-730		425	I
10/2/25 16:30	8/21/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	6	S.d	-23,549	356.81	-66		37	D
10/2/25 16:15	9/30/25	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Klee Justin B.	MA	DO	Co-CEO	1	S	-431	14.38	-30		3,325	D
10/2/25 16:15	9/30/25	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mazzariello Gina	MA	O	GC	2	S.m	-375	9.65	-39		157	D
10/2/25 16:15	9/30/25	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Frates James M	MA	O	CFO	1	S	-155	14.65	-11		307	D
10/2/25 16:15	9/30/25	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cohen Joshua B	MA	DO	Co-CEO	1	S	-429	14.35	-30		3,325	D
10/2/25 16:15	9/30/25	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bedrosian Camille L	MA	O	Chief Me	1	S	-176	14.58	-12		182	D
10/1/25 20:14	8/25/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Noci Darlene	MA	O	Chief De	3	S.d	-952	79.35	-12		48	D
10/1/25 19:17	10/1/25	XENE	Xenon Pharmaceuticals Inc.	A1	Health	Drug	Pharmaceutical Preparations	Mortimer Ian	A1	DO	P,CEO,IN	1	S.d	-1,004	40.16	-25		46	D
10/1/25 17:22	9/29/25	MLTX	Moonlake Immunotherapeutics	E9	Health	Drug	Pharmaceutical Preparations	Chen Bihua	MA	H	Former 1	1	S.m	-46,868	7.21	-6,500		1,994	I
10/1/25 17:16	9/29/25	PGEN	Precigen, Inc.	VA	Health	Drug	Pharmaceutical Preparations	Kindler Jeffrey B	MD	D		1	S.m	-604	3.47	-174		346	D
10/1/25 16:57	9/29/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Meisner Lara	MA	O	GC	2	S.d	-681	13.71	-50	-100	0	D
10/1/25 16:55	9/30/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Geary Richard S	CA	O	EVP,Chie	3	S.d	-4,710	60.46	-78		89	D
10/1/25 16:46	9/29/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hohl Benjamin	CO	O	CFO	3	S.d	-200	20.50	-10		23	D
10/1/25 16:30	9/29/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	O'Malley Brendan M.	OH	O	SVP,GC	2	S	-54	5.40	-10		360	D
10/1/25 16:30	7/22/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Vazzano Joseph Walter	OH	O	CFO	3	S	-169	6.62	-26		478	D
10/1/25 16:24	10/1/25	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chole Timothy	MI	O	SVP,CCO	1	S	-3	1.19	-3		125	D
10/1/25 16:23	10/1/25	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Neri Jesse	MI	O	SVP,CFO	1	S	-1	1.19	-1		126	D
10/1/25 16:22	10/1/25	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Strobeck Mark	MI	DO	P,CEO	1	S	-8	1.19	-7		331	D
10/1/25 16:10	9/9/25	PAHC	Phibro Animal Health Corp	DE	Health	Drug	Pharmaceutical Preparations	Bendheim Jack	NJ	DOT	P,CEO	3	S.dm	-1,974	40.46	-49		78	I
10/1/25 16:00	9/30/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Loumeau Eric J	CA	O	GC	1	S.d	-239	29.00	-8		9	D
9/30/25 18:59	9/29/25	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Azoy Alexander	CA	O	Chief Ac	2	S	-56	12.60	-4		30	D
9/30/25 17:56	9/26/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jones Cecilia	MA	O	CFO	1	S.d	-134	36.77	-4		34	D
9/30/25 17:53	9/26/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lyssikatos Joseph P	CO	O	CHIEF SC	5	S.m	-774	20.63	-38		953	I
9/30/25 17:51	9/26/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kintz Samuel	CO	DO	P,CEO	6	S.m	-778	20.74	-38		940	I
9/30/25 17:44	9/30/25	PGEN	Precigen, Inc.	VA	Health	Drug	Pharmaceutical Preparations	Kirk Randal J	VA	DT		2	S.dm	-24,824	3.65	-6,810		128,722	I
9/30/25 16:42	9/26/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Struthers Richard Scott	CA	DO	P,CEO	1	S	-180	45.00	-4	0	1,298	I
9/30/25 16:41	9/26/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fust Matthew K	CA	D		1	S.d	-716	44.75	-16		23	D
9/30/25 16:09	8/26/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cloonan Michael	MA	DO	P,CEO	3	S.dm	-1,921	25.61	-75		547	D
9/29/25 19:30	9/29/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Powl Brian T.	CA	O	Chief Co	1	S	-80	8.94	-9		100	D
9/29/25 19:30	9/29/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bair Teresa Brophy	CA	O	GC	1	S	-79	8.94	-9		148	D
9/29/25 19:30	9/29/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ford Kathleen	CA	O	COO	1	S	-62	8.94	-7		63	D
9/29/25 19:30	9/29/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Leoni Mollie	CA	O	Chief Me	1	S	-110	8.94	-12		158	D
9/29/25 19:30	9/5/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Wilson Troy Edward	CA	DO	P,CEO	3	S.d	-6,080	37.72	-161		1,538	D
9/29/25 19:30	9/29/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Doyle Thomas James	CA	O	SVP,Fina	1	S	-41	8.94	-5		110	D
9/29/25 16:26	9/26/25	AQST	Aquestive Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Barber Daniel	NJ	DO	P,CEO	2	S	-554	6.03	-92		1,015	D
9/29/25 16:26	9/26/25	AQST	Aquestive Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Boyd Peter E.	NJ	O	See Rema	2	S	-143	5.70	-25		288	D
9/29/25 16:15	9/25/25	TNGX	Tango Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Third Rock Ventures Iv, L.P.	MA	T		5	S.m	-21,505	7.18	-2,995		15,759	D
9/26/25 19:43	9/24/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Kapusta Matthew C	P7	DO	CEO,MD	1	S.d	-9,382	41.46	-226		651	D
9/26/25 19:37	9/24/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Klemt Christian	P7	O	CFO	1	S.dm	-945	52.51	-18		218	D
9/26/25 15:53	9/24/25	MNPR	Monopar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	Tactic Pharma LLC	IL	T		1	S	-35,000	63.61	-550		272	D
9/25/25 16:31	9/24/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Causey Christopher	MD	D		2	S.d	-1,710	427.41	-4		5	D
9/24/25 19:42	9/22/25	OKUR	Onkure Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Saccomano Nicholas A	CO	DO	P,CEO	1	S	0	2.63	0		4	D
9/24/25 19:41	9/22/25	OKUR	Onkure Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Leverone Jason A.	CO	O	CFO	1	S	-1	2.62	0		13	D
9/24/25 19:00	9/24/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Bush Tia L	X0	O	Chief Te	2	S.dm	-1,886	22.24	-85		122	D
9/24/25 17:11	9/23/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Aryeh Jason	FL	D		1	S	-1,708	170.81	-10		126	D
9/24/25 16:30	9/22/25	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	Calkins Daniel	MA	O	CFO	1	S.m	-1	9.12	0	0	110	D
9/24/25 16:05	9/22/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	Reed Elizabeth E	CA	O	GC,GC	1	S.d	-250	25.00	-10		90	D
9/23/25 17:32	9/22/25	XOMA	Xoma Royalty Corp	NV	Health	Drug	Pharmaceutical Preparations	Burns Thomas M.	CA	O	SVP,Fina	1	S.d	-156	35.99	-4		40	D
9/23/25 16:57	9/22/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hughes Steven George	CA	O	Chief Me	5	S.d	-3,814	42.89	-89		39	D
9/23/25 16:33	9/19/25	LVTX	Lava Therapeutics Nv	P7	Health	Drug	Pharmaceutical Preparations	Versant Venture Capital Vi, L.P.	CA	T		2	S.m	-6,571	1.43	-4,588		2,903	M
9/22/25 19:00	9/22/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jacobson Mark L.	NY	O	COO	2	S.d	-6,401	114.74	-56	-100	0	D
9/22/25 17:14	9/19/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Davis Krista	MN	O	SVP,CHRO	2	S	-259	93.61	-3		63	D
9/19/25 18:23	9/18/25	RARE	Ultragenyx Pharmaceutical Inc.	DE	Health	Drug	Pharmaceutical Preparations	Huizenga Theodore Alan	CA	O	SVP,Chie	2	S	-5	30.43	0	0	50	D
9/19/25 16:49	9/19/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Olian Judy D.	MD	D		1	S	-748	415.43	-2		5	D
9/18/25 21:30	9/16/25	OLMA	Olema Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Harmon Cyrus	CA	D		1	S.m	-205	8.19	-25		861	M
9/18/25 18:16	9/16/25	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	Stuglik Brian M	MA	D		1	S	-6	9.99	-1		102	D
9/18/25 18:14	9/16/25	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	Gagnon Robert E.	MA	D		1	S	-3	9.99	0		42	D
9/18/25 18:11	9/16/25	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	Paterson Dan	MA	DO	P,CEO	2	S	-12	6.76	-2	0	443	D
9/18/25 16:45	9/16/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Oyler John	V8	DO	CEO	1	S	-9,056	325.71	-28	0	53,506	D
9/18/25 16:06	9/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Looker Benjamin	MI	O	GC	1	S	-18	2.80	-6		394	D
9/18/25 16:06	9/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Koenig Sheldon L.	MI	DO	P,CEO	1	S	-79	2.79	-28		1,519	D
9/18/25 16:06	9/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Halladay Benjamin	MI	O	CFO	1	S	-20	2.81	-7		475	D
9/18/25 16:01	9/16/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Watson David O.	MA	O	GC	3	S	-784	26.14	-30		204	D
9/17/25 20:08	9/15/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chopas James George	MA	O	VP,Chief	2	S	-20	27.08	-1		54	D
9/17/25 19:39	9/16/25	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	Tross Stuart A	CT	O	Chief Pe	1	S	-251	5.34	-47		1,032	D
9/17/25 16:31	8/15/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Porter James Richard	MA	DO	P,CEO	2	S.d	-4,171	77.25	-54		249	D
9/17/25 16:30	9/15/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Singh Raman	NC	D		2	S.d	-1,396	26.32	-53		31	D
9/17/25 16:03	9/15/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McCarthy Teresa	CA	O	CHRO	2	S.d	-1,087	43.47	-25		97	D
9/16/25 21:45	9/12/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dunton Alan W	NJ	D		1	S.d	-131	13.13	-10		40	D
9/16/25 18:16	7/29/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Accardi Mario Alberto	X0	O	P,Orexin	3	S.d	-442	18.80	-23		208	D
9/16/25 18:00	9/15/25	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Schneyer Mark C.	CA	O	EVP,CFO	2	S	-637	24.97	-25		43	D
9/16/25 16:35	9/15/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Paulson Richard A.	MA	DO	P,CEO	1	S	-8	6.43	-1		84	D
9/16/25 16:34	9/15/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mano Michael	MA	O	SVP,GC,S	1	S	-2	6.43	0		21	D
9/16/25 16:33	9/15/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Poulton Stuart	MA	O	EVP,Chie	2	S	-3	5.77	-1		28	D
9/16/25 16:32	9/15/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rangwala Reshma	MA	O	EVP,Chie	1	S	-3	6.43	0		29	D
9/16/25 16:31	9/15/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cheng Sohanya Roshan	MA	O	EVP,Chie	1	S	-2	6.43	0		36	D
9/15/25 17:39	9/12/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mottola Frank	MD	O	SVP,Chie	2	S.d	-852	44.87	-19		15	D
9/15/25 16:26	9/12/25	MRSN	Mersana Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Huber Martin H. Jr.	MA	DO	P,CEO	1	S.d	-15	7.31	-2		10	D
9/15/25 16:23	9/12/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Schaeffer Orlov S Nicole	NJ	O	Chief Pe	2	S.d	-12,403	143.36	-87		80	D
9/15/25 16:22	9/12/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Sharoky Melvin Md	NJ	D		3	S	-3,965	132.16	-30		334	M
9/15/25 12:45	9/12/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Callicutt Jack W	GA	O	CFO	1	S.d	-56	6.44	-9		8	D
9/15/25 12:45	9/12/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Lewis Joel	GA	DO	P,CEO	1	S.d	-89	6.36	-14		835	D
9/12/25 21:45	9/12/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	Todisco Joseph	NJ	O	CEO	1	S.d	-650	13.00	-50		509	D
9/12/25 20:39	9/11/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yale Catriona	CA	O	Chief De	1	S	-28	43.02	-1		91	D
9/12/25 20:38	9/11/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	White William Richard	CA	O	CFO	1	S	-28	43.02	-1		58	D
9/12/25 20:00	9/11/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Brege Laura	CA	D		1	S.d	-1,265	74.40	-17		16	D
9/12/25 20:00	9/12/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bjerkholt Eric	CA	O	CFO	2	S.d	-728	41.42	-18		40	D
9/12/25 18:00	9/11/25	VTRS	Viatris Inc	DE	Health	Drug	Pharmaceutical Preparations	Le Goff Corinne	PA	O	Chief Co	1	S	-72	10.25	-7		35	D
9/12/25 17:30	9/11/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	Hariri Robert J	TN	D		2	S.d	-286	9.52	-30		51	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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