Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	Title	#f	T	TVal	Price	Qty	oc	Own	H
1/15/26 21:00	1/13/26	OLMA	Olema Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kovacs Shane William Charles	CA	O	CH. OPER	1	S.m	-2,980	28.70	-104		140	D
1/15/26 19:07	1/13/26	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rodman David Malcom	PA	O	Chief Me	3	S.dm	-10,161	35.00	-290		62	D
1/15/26 18:24	1/13/26	PAHC	Phibro Animal Health Corp	DE	Health	Drug	Pharmaceutical Preparations	Bendheim Jack	NJ	DOT	P,CEO	16	S.dm	-8,188	42.84	-191		91	I
1/15/26 17:22	10/27/25	HOWL	Werewolf Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Evnin Luke	MA	D		17	S.m	-2,057	0.9744	-2,111		4,133	I
1/15/26 16:34	1/13/26	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chopas James George	MA	O	VP,Chief	1	S	-19	22.19	-1		53	D
1/15/26 16:33	1/13/26	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Delong Mark Jeffrey	MA	O	Chief Bu	1	S	-39	22.19	-2		83	D
1/15/26 16:32	1/15/26	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	8	S.d	-39,065	472.94	-83		37	D
1/15/26 16:32	1/13/26	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Deschatelets Pascal	MA	O	Chief Sc	1	S	-51	22.19	-2	0	1,158	D
1/15/26 16:31	1/13/26	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Francois Cedric	MA	DO	CEO	1	S	-226	22.19	-10		1,636	D
1/15/26 16:30	1/13/26	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Nicholson Nur	MA	O	Chief Te	1	S	-58	22.19	-3		81	D
1/15/26 16:29	1/13/26	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sullivan Timothy Eugene	MA	O	CFO	2	S.d	-366	26.40	-14		171	D
1/15/26 16:28	1/13/26	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Watson David O.	MA	O	GC	3	S	-351	22.24	-16		169	D
1/15/26 16:22	1/13/26	BIOA	Bioage Labs, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Goldstein Dov A Md	CA	O	CFO	1	S.d	-532	19.70	-27		22	D
1/15/26 16:20	1/13/26	BIOA	Bioage Labs, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fortney Kristen	CA	DO	CEO	1	S	-4,223	18.12	-233		977	D
1/14/26 21:30	1/12/26	OLMA	Olema Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Myles David C.	CA	O	CH. DISC	2	S.dm	-4,661	28.95	-161		711	M
1/14/26 21:00	1/12/26	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Venker Eric	X0	O	P,Immuno	4	S.dm	-18,778	21.46	-875		1,655	D
1/14/26 18:14	1/13/26	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Cook Meredith	MN	O	SVP,GC,S	2	S	-77	85.64	-1		75	D
1/14/26 17:25	1/12/26	OMER	Omeros Corp	WA	Health	Drug	Pharmaceutical Preparations	Borges David J.	WA	O	VP,Finan	1	S.dm	-751	12.52	-60	-100	0	D
1/14/26 17:12	1/12/26	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	Paterson Dan	MA	DO	P,CEO	8	S.m	-396	9.43	-42		439	D
1/14/26 17:11	1/12/26	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	Calkins Daniel	MA	O	CFO	2	S	-37	7.17	-5		110	D
1/14/26 16:26	1/12/26	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Gut Robert	P7	D		2	S.d	-1,487	26.07	-57		40	D
1/14/26 16:23	1/12/26	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Garg Pushkal	MA	O	EVP Chie	1	S	-548	362.87	-2		23	D
1/14/26 16:23	1/12/26	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Greenstreet Yvonne	MA	DO	CEO	2	S.dm	-15,088	428.31	-35		79	D
1/14/26 16:22	1/12/26	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Poulton Jeffrey V.	MA	O	EVP,CFO	1	S	-1,009	362.87	-3		58	D
1/14/26 16:22	1/12/26	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Tanguler Tolga	MA	O	EVP,Chie	1	S	-548	362.87	-2		30	D
1/14/26 16:21	1/12/26	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Fitzgerald Kevin Joseph	MA	O	CSO,EVP,	2	S.dm	-6,880	431.94	-16		22	D
1/14/26 12:56	11/24/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	Moreadith Randall	AL	O	Chief Sc	18	S.dm	-300	3.56	-85		6	D
1/13/26 20:43	11/11/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Congleton Jon	PA	DO	CEO	2	S	-9,618	44.48	-216		639	D
1/13/26 20:43	11/11/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Levy Adam Scott	PA	O	CFO,Secr	2	S.d	-5,709	43.82	-130		19	D
1/13/26 17:54	1/9/26	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Patel Anish	CO	O	COO	3	S	-1,608	26.09	-62		270	I
1/13/26 17:37	1/9/26	RPRX	Royalty Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Urist Marshall	NY	O	EVP,Rese	7	S	-7,193	39.27	-183		228	I
1/13/26 17:11	1/12/26	ZYME	Zymeworks Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hollywood Mark	DE	O	EVP,COO	1	S.d	-139	22.67	-6		133	D
1/13/26 17:10	1/12/26	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Benkowitz Michael	MD	O	P,COO	14	S.d	-137,455	469.93	-293		3	I
1/13/26 16:47	1/9/26	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Friedman Paul A	PA	D		3	S.d	-26,657	537.45	-50		843	D
1/13/26 16:38	1/9/26	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Taub Rebecca	PA	D		3	S.d	-20,047	537.45	-37		1,111	D
1/13/26 16:36	1/12/26	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Krepp Sarah	NC	O	Chief Hu	2	S.d	-500	37.34	-13		141	D
1/13/26 16:36	1/12/26	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Moomaw Scott	NC	O	Chief Co	2	S.d	-795	37.23	-21		155	D
1/13/26 16:34	1/12/26	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Kaseta Michael	NC	O	CFO,COO	2	S.d	-1,420	37.27	-38		354	D
1/13/26 16:34	1/12/26	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Adair Jason	NC	O	Chief Bu	4	S.d	-1,616	31.94	-51		184	D
1/13/26 16:33	1/12/26	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Schundler Russell	NC	O	GC	2	S.d	-1,056	37.23	-28		594	D
1/13/26 16:33	1/12/26	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Jeffs Roger	NC	DO	CEO	1	S.d	-2,493	37.43	-67		2,626	D
1/13/26 16:31	1/12/26	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Boyle Dana	NC	O	Chief Ac	4	S.d	-1,176	28.38	-41		184	D
1/13/26 16:31	1/12/26	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Saggar Rajeev	NC	O	Chief Me	2	S.d	-2,719	29.38	-93		177	D
1/13/26 16:04	12/18/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Lewis William	NJ	DO	Chair,CE	4	S.dm	-8,918	177.33	-50		600	D
1/13/26 16:03	1/9/26	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Flammer Martina M.D.	NJ	O	Chief Me	5	S.dm	-13,101	184.93	-71		95	D
1/12/26 21:01	1/8/26	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kumar Neil	CA	DO	CEO	5	S.dm	-20,897	70.56	-296		5,623	I
1/12/26 21:00	1/12/26	ZYME	Zymeworks Inc.	DE	Health	Drug	Pharmaceutical Preparations	Smith Jeffrey T L	DE	O	EVP,Chie	2	S.d	-476	23.96	-20		27	D
1/12/26 20:32	1/12/26	ZYME	Zymeworks Inc.	DE	Health	Drug	Pharmaceutical Preparations	Moore Paul Andrew	DE	O	Chief Sc	2	S.d	-721	24.32	-30		48	D
1/12/26 19:07	1/12/26	ZYME	Zymeworks Inc.	DE	Health	Drug	Pharmaceutical Preparations	Galbraith Kenneth	DE	DO	Chair,CE	3	S.d	-3,338	25.23	-132		227	D
1/12/26 17:12	1/8/26	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lyssikatos Joseph P	CO	O	CHIEF SC	4	S.m	-4,115	25.33	-163		915	I
1/12/26 17:11	1/8/26	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Heyman Richard A.	CO	D		1	S.m	-348	25.02	-14		149	I
1/12/26 16:38	1/8/26	CLNN	Clene Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ugwumba Chidozie	AR	T		7	S.dm	-2,370	6.46	-367		796	I
1/12/26 16:21	1/9/26	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Kaye Jack	P7	D		2	S.d	-1,352	29.91	-45		20	D
1/12/26 16:10	1/8/26	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	Taiwan Carbon Nano Technology Corp	F5	T		1	S.m	-2	1.82	-1	0	1,036	D
1/9/26 20:30	1/8/26	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	Tross Stuart A	CT	O	Chief Pe	1	S	-298	6.33	-47		985	D
1/9/26 19:34	1/7/26	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	Davidson Michael H.	P7	DO	CEO	1	S.d	0	0.00	-12		460	D
1/9/26 19:16	1/8/26	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Lizzul Paul F.	CA	O	Chief Me	4	S.d	-522	44.94	-12		42	D
1/9/26 19:14	1/8/26	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Mulroy Dennis	CA	O	CFO	5	S.d	-1,549	46.23	-34		22	D
1/9/26 19:13	1/8/26	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Loumeau Eric J	CA	O	GC	5	S.dm	-2,204	46.44	-47		13	D
1/9/26 19:12	1/8/26	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Faga Daniel	CA	DO	P,CEO	3	S.d	-1,716	44.23	-39		479	D
1/9/26 18:59	1/8/26	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Williams Laura A	MA	O	Chief Pa	2	S.d	-384	6.81	-56		362	D
1/9/26 17:37	1/8/26	EQ	Equillium, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tom Penny	CA	O	Principa	1	S.d	-8	1.29	-7	-100	0	D
1/9/26 17:34	1/8/26	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	McCulloch Kevin	IL	O	See Rema	1	S	-120	8.00	-15		1,710	D
1/9/26 17:15	1/7/26	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Lee Chan Henry	V8	O	SVP,GC	3	S.dm	-782	336.33	-2		223	D
1/9/26 17:13	1/7/26	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Boyce Sarah	CA	DO	P,CEO	1	S	-619	72.23	-9		283	D
1/9/26 17:13	1/7/26	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Calderaro Charles III	CA	O	Chief Te	1	S	-269	72.23	-4		50	D
1/9/26 17:13	1/7/26	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McCarthy Teresa	CA	O	CHRO	1	S	-142	72.23	-2		117	D
1/9/26 17:12	1/7/26	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Moriarty John B	CA	O	GC	1	S	-171	72.23	-2		75	D
1/9/26 17:12	1/7/26	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Maclean Michael F	CA	O	CFO	1	S	-143	72.23	-2		64	D
1/9/26 17:12	1/7/26	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hughes Steven George	CA	O	Chief Me	2	S.d	-276	60.33	-5		39	D
1/9/26 17:12	1/7/26	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Flanagan W. Michael	CA	O	Chief Sc	1	S	-171	72.23	-2		92	D
1/9/26 17:08	1/7/26	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Devers Shannon L.	CA	O	EVP,Chie	2	S.d	-5,118	83.94	-61		17	D
1/9/26 16:53	1/7/26	MIST	Milestone Pharmaceuticals Inc.	A8	Health	Drug	Pharmaceutical Preparations	Oliveto Joseph	A8	DO	P,CEO	1	S.m	-98	2.25	-44		304	D
1/9/26 16:35	1/8/26	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Ragosa Mark	X0	O	CFO	4	S.d	-3,099	41.41	-75		31	D
1/9/26 16:05	1/7/26	VRTX	Vertex Pharmaceuticals Inc / Ma	MA	Health	Drug	Pharmaceutical Preparations	Tatsis Ourania	MA	O	EVP,Chie	2	S	-4,162	462.49	-9		47	D
1/8/26 21:20	1/7/26	ERAS	Erasca, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Garner Ebun	CA	O	GC,Corp.	1	S.d	-671	5.59	-120		25	D
1/8/26 20:42	1/7/26	XCUR	Exicure, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Exicure Hitron Inc.	MA	T		1	S	-3,336	4.50	-741		5,925	D
1/8/26 20:35	1/6/26	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Guyer William	CA	O	Chief De	5	S.d	-4,540	65.80	-69		5	D
1/8/26 20:27	1/6/26	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Auerbach Alan H	CA	DOT	P,CEO	1	S.m	-205	5.86	-35	0	7,146	D
1/8/26 20:15	1/6/26	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hunt Douglas M	CA	O	See Rema	1	S.m	-53	5.86	-9		156	D
1/8/26 20:14	1/6/26	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Nougues Maximo F	CA	O	CFO	1	S.m	-64	5.86	-11		193	D
1/8/26 17:23	1/8/26	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	Hopkinson Craig C.	MA	O	EVP R,D,	5	S.d	-765	29.71	-26		70	D
1/8/26 17:22	1/6/26	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Adsett Roger	NJ	O	COO	1	S.m	-747	174.06	-4		108	D
1/8/26 17:21	1/6/26	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Bonstein Sara	NJ	O	CFO	1	S.m	-809	174.22	-5		81	D
1/8/26 17:19	1/6/26	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Smith Michael Alexander	NJ	O	GC	2	S.dm	-5,535	182.76	-30		57	D
1/8/26 16:20	1/6/26	RNAC	Cartesian Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Brunn Carsten	MD	DO	P,CEO	1	S	-162	6.82	-24		324	D
1/8/26 16:19	1/6/26	RNAC	Cartesian Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Miljkovic Milos	MD	O	Chief Me	1	S	-24	6.82	-4		59	D
1/8/26 16:19	1/6/26	RNAC	Cartesian Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Davis Blaine	MD	O	CFO	1	S	-72	6.82	-11		121	D
1/8/26 16:05	11/25/25	CVRX	Cvrx, Inc.	NJ	Health	Drug	Pharmaceutical Preparations	Johnson & Johnson	NJ	T		5	S.m	-861	10.14	-85		4,051	I
1/8/26 16:05	1/6/26	HROW	Harrow, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T		1	S	-1,067	53.35	-20		3,885	I
1/8/26 16:05	1/6/26	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Frates James M	MA	O	CFO	1	S	-37	11.11	-3		304	D
1/8/26 16:05	1/6/26	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cohen Joshua B	MA	DO	Co-CEO	1	S	-86	11.09	-8	0	3,318	D
1/8/26 16:05	1/6/26	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Klee Justin B.	MA	DO	Co-CEO	1	S	-86	11.09	-8	0	3,318	D
1/8/26 16:04	1/6/26	VRTX	Vertex Pharmaceuticals Inc / Ma	MA	Health	Drug	Pharmaceutical Preparations	Wagner Charles F Jr	MA	O	EVP,CO,F	2	S.d	-10,778	458.03	-24		38	D
1/8/26 16:03	1/7/26	REGN	Regeneron Pharmaceuticals, Inc.	NY	Health	Drug	Pharmaceutical Preparations	Bassler Bonnie L	NY	D		2	S.d	-1,770	783.19	-2		2	D
1/8/26 16:00	1/7/26	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	Lilly Endowment Inc	IN	T		23	S.e	-1,027,443	389.72	-2,636		94,232	D
1/7/26 20:15	1/5/26	ANTX	An2 Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Day Lucy	CA	O	CFO	1	S.m	-9	1.01	-9		75	D
1/7/26 20:15	1/5/26	ANTX	An2 Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Prior Stephen David	CA	O	Chief St	2	S.m	-7	1.02	-7		66	D
1/7/26 20:13	1/5/26	ANTX	An2 Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chanda Sanjay	CA	O	Chief De	1	S.m	-9	1.01	-9		76	D
1/7/26 20:12	1/5/26	ANTX	An2 Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Eizen Joshua M	CA	O	See Rema	2	S.m	-28	1.02	-28		177	D
1/7/26 19:00	1/5/26	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tabuteau Herriot	NY	DOT	CEO	3	S.dm	-57,346	149.60	-383		7,352	D
1/7/26 18:31	1/5/26	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	Kastelein Johannes Jacob Pieter	P7	DO	Chief Sc	1	S.d	-200	33.25	-6		99	D
1/7/26 18:27	1/5/26	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	Kooij Louise Frederika	P7	O	Chief Ac	2	S.dm	-5,285	35.79	-148		24	D
1/7/26 18:27	1/5/26	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	Somaiya Mayur Ian	P7	O	CFO	1	S.d	-170	33.25	-5		58	D
1/7/26 17:46	12/15/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Burnett Patrick	CA	O	See Rema	5	S.dm	-1,028	26.08	-39		98	D
1/7/26 17:27	1/5/26	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pelish Henry E.	MA	O	Chief Sc	1	S.dm	-502	97.24	-5		83	D
1/7/26 17:26	1/5/26	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Noci Darlene	MA	O	Chief De	4	S.dm	-1,967	101.33	-19		58	D
1/7/26 17:26	1/5/26	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Miller Deborah Ann	MA	O	GC	5	S.dm	-6,958	102.39	-68		60	D
1/7/26 17:26	1/5/26	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Turner Christopher Durant	MA	O	Chief Me	1	S.dm	-721	97.25	-7		73	D
1/7/26 17:25	1/5/26	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Balcom Alexandra	MA	O	CFO	3	S.dm	-3,568	101.27	-35		99	D
1/7/26 17:25	1/5/26	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Porter James Richard	MA	DO	P,CEO	1	S.dm	-2,668	97.26	-27		325	D
1/7/26 17:11	1/5/26	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kalofonos Isabel	CA	O	Chief Co	1	S.d	-138	55.00	-3		1	D
1/7/26 16:30	1/6/26	ALXO	Alx Oncology Holdings Inc	DE	Health	Drug	Pharmaceutical Preparations	Pinto Shelly	CA	O	SVP,Fina	1	S	-4	1.11	-4		88	D
1/7/26 16:23	1/5/26	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Milanova Tsveta	MA	O	Chief Co	2	S.d	-157	27.06	-6		35	D
1/7/26 16:15	1/5/26	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jaen Juan C.	CA	O	P	6	S.m	-6,310	21.97	-287		1,459	I
1/7/26 16:05	1/5/26	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	Inrig Jula	CA	O	Chief Me	2	S.dm	-728	41.68	-17		89	D
1/7/26 16:05	1/5/26	IRWD	Ironwood Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Silver Ronald	MA	O	Principa	1	S	-163	4.60	-35		277	D
1/7/26 12:45	1/5/26	ACTU	Actuate Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Thomson Todd S	CA	DT		1	S	-1,624	5.80	-280		2,354	I
1/6/26 21:36	1/2/26	SYRE	Spyre Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Turtle Cameron	MA	DO	CEO	3	S	-1,945	25.94	-75		702	D
1/6/26 21:30	1/2/26	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	Francis Chris	MA	O	See Rema	2	S.d	-6,577	14.60	-450		25	D
1/6/26 20:26	1/5/26	TERN	Terns Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Burroughs Amy L.	CA	DO	CEO	1	S.d	-2,718	38.10	-71		147	D
1/6/26 20:25	1/2/26	TERN	Terns Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kuriakose Emil	CA	O	Chief Me	1	S	-45	38.57	-1		50	D
1/6/26 20:22	1/2/26	ATAI	Ataibeckley Inc.	DE	Health	Drug	Pharmaceutical Preparations	Feilding-Mellen Cosmo	NY	D		1	S	-154	3.90	-40		7,663	D
1/6/26 20:00	1/2/26	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Thompson Travis Alvin	X0	O	Chief Ac	1	S.dm	-16	6.64	-2		66	D
1/6/26 20:00	1/2/26	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Skynner Michael	X0	O	CTO	1	S.dm	-42	6.62	-6		162	D
1/6/26 20:00	1/2/26	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Hannay Michael Charles Ferguson	X0	O	CHIEF PR	1	S.dm	-34	6.64	-5		98	D
1/6/26 20:00	1/2/26	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Milnes Alistair	X0	O	COO	1	S.dm	-44	6.63	-7		137	D
1/6/26 20:00	1/2/26	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Young Alethia	X0	O	CFO	1	S.dm	-50	6.62	-8		87	D
1/6/26 20:00	1/2/26	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Lee Kevin	X0	DO	CEO	1	S.dm	-141	6.62	-21		619	D
1/6/26 19:47	1/2/26	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Kozarich John W	FL	D		3	S	-269	192.15	-1		45	D
1/6/26 18:14	1/5/26	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	Shannon John Patrick Jr	IL	DO	See Rema	2	S.d	-350	7.26	-48		2,798	D
1/6/26 17:35	1/2/26	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Swayze Eric	CA	O	EVP Rese	1	S.d	-1,856	79.12	-23		31	D
1/6/26 17:31	12/1/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Welgus Howard G.	CA	D		3	S	-844	28.15	-30		90	D
1/6/26 17:30	1/5/26	PCRX	Pacira Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Riker Lauren	CA	O	SVP,Fina	1	S	-34	24.24	-1		59	D
1/6/26 16:54	1/2/26	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Lewis Joel	GA	DO	P,CEO	6	S.dm	-621	4.70	-132		835	D
1/6/26 16:54	1/2/26	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Callicutt Jack W	GA	O	CFO	5	S.dm	-944	5.36	-176		15	D
1/6/26 16:53	1/2/26	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Jamil Khurram	GA	O	Chief Me	4	S.dm	-1,065	5.10	-209		4	D
1/6/26 16:31	1/6/26	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Causey Christopher	MD	D		2	S.d	-1,010	505.01	-2		4	D
1/6/26 16:31	1/5/26	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Malcolm Jan	MD	D		3	S	-75	496.71	0		0	D
1/6/26 16:30	1/2/26	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Schambye Hans T.	G7	DO	CEO	1	S.d	-15	21.38	-1		5	D
1/6/26 16:30	1/2/26	FULC	Fulcrum Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gould Robert J	MA	D		2	S	-344	11.45	-30		485	D
1/6/26 16:30	1/2/26	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Winslow Garrett	G7	O	GC	1	S.d	-5	21.38	0		2	D
1/6/26 16:30	1/2/26	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Firmani Lori	G7	O	CFO	1	S.d	-3	21.41	0		1	D
1/6/26 16:24	1/2/26	BIOA	Bioage Labs, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rubin Paul D	CA	O	Chief Me	3	S.d	-1,013	10.74	-94	-100	0	D
1/6/26 16:18	1/2/26	RPRX	Royalty Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Coyne Terrance P.	NY	O	EVP,CFO	5	S	-13,534	38.90	-348		829	I
1/6/26 16:16	1/5/26	CTNM	Contineum Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lorrain Daniel S.	CA	O	Chief Sc	2	S	-95	11.34	-8		171	D
1/6/26 16:06	1/5/26	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Baumal Caroline	MA	O	Chief Me	1	S	-77	25.53	-3		91	D
1/6/26 16:03	11/12/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Schaeffer Orlov S Nicole	NJ	O	Chief Pe	2	S.d	-21,113	180.01	-117		42	D
1/6/26 16:02	12/24/25	LYEL	Lyell Immunopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bulis Veronica Sanchez	CA	O	VP,Corpo	2	S.m	-78	33.76	-2		9	D
1/5/26 21:50	1/5/26	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	O'Brien Patrick	CA	O	COO	1	S	-3,123	63.11	-49		475	D
1/5/26 21:41	1/5/26	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hamilton James C	CA	O	Chief Me	1	S	-2,535	63.11	-40		172	D
1/5/26 21:39	1/2/26	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Anzalone Christopher Richard	CA	DO	CEO	5	S.dm	-24,011	66.65	-360		3,917	D
1/5/26 20:31	1/5/26	VKTX	Viking Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Zante Greg	CA	O	CFO	2	S.d	-2,113	33.10	-64		190	D
1/5/26 20:31	1/5/26	VKTX	Viking Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mancini Marianna	CA	O	COO	2	S.d	-2,118	33.17	-64		409	D
1/5/26 20:28	1/5/26	VKTX	Viking Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lian Brian	CA	DO	P,CEO	2	S.d	-9,057	33.25	-272		2,499	D
1/5/26 20:25	1/2/26	VKTX	Viking Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Foehr Matthew W	CA	D		1	S.d	-562	35.11	-16		135	D
1/5/26 20:02	1/2/26	IRON	Disc Medicine, Inc.		Health	Drug	Pharmaceutical Preparations	Khara Rahul	MA	O	GC	1	S.d	-511	78.69	-7		38	D
1/5/26 18:01	1/2/26	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	Hecht Beth	IL	O	See Rema	3	S	-364	7.28	-50		1,337	D
1/5/26 16:30	1/2/26	XLO	Xilio Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Brennan Kevin M.	MA	O	SVP,FINA	1	S.d	-1	0.6429	-2		6	D
1/5/26 16:30	1/2/26	XLO	Xilio Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Frankenfield Christopher James	MA	O	CFO	1	S.d	-5	0.6432	-7		25	D
1/5/26 16:26	1/5/26	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Callos Andrew	CA	O	EVP,Chie	5	S.d	-4,660	64.60	-72		51	D
1/5/26 16:20	12/31/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bredt David	MA	O	Chief Sc	3	S	-667	28.28	-24		404	D
1/5/26 16:19	12/31/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yeleswaram Krishnaswamy	MA	O	Chief De	1	S	-85	30.05	-3		297	D
1/5/26 16:15	1/2/26	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hunter Heather	MI	O	COO	1	S	-2	0.8354	-3		133	D
1/5/26 16:13	1/2/26	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Neri Jesse	MI	O	SVP,CFO	1	S	-1	0.8352	-1		125	D
1/5/26 16:07	1/2/26	RARE	Ultragenyx Pharmaceutical Inc.	DE	Health	Drug	Pharmaceutical Preparations	Horn Howard	CA	O	CFO	2	S	-184	29.54	-6		95	D
1/2/26 21:30	12/30/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dunton Alan W	NJ	D		1	S.d	-260	13.00	-20		40	D
1/2/26 21:00	1/2/26	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Meyer Andrew Hollman	CA	O	Chief Bu	4	S.d	-737	29.22	-25		85	D
1/2/26 21:00	1/2/26	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Diraimondo Thomas	CA	O	Chief Sc	1	S.d	-34	13.73	-3		156	D
1/2/26 21:00	1/2/26	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Campbell David Alan	CA	DO	P,CEO	1	S.d	-111	13.73	-8		382	D
1/2/26 21:00	1/2/26	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Winter Charles M.	CA	O	Chief Te	1	S.d	-33	13.73	-2		106	D
1/2/26 21:00	1/2/26	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McIver Zachariah	CA	O	Chief Me	1	S.d	-37	13.73	-3		52	D
1/2/26 21:00	1/2/26	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dobek Maria	CA	O	VP,Accou	1	S.d	-20	13.73	-1		34	D
1/2/26 20:25	1/2/26	ORKA	Oruka Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sandler Laura Lee	CA	O	COO	1	S.d	-371	28.52	-13		205	D
1/2/26 20:18	12/30/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Burns James William	MA	O	GC	1	S.d	-79	27.09	-3		32	D
1/2/26 20:16	12/30/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Goff Brian	MA	DO	CEO	1	S.d	-507	27.09	-19		143	D
1/2/26 20:15	10/30/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gheuens Sarah	MA	O	Chief Me	4	S.d	-341	38.33	-9		65	D
1/2/26 20:14	12/30/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jones Cecilia	MA	O	CFO	1	S.d	-79	27.09	-3		37	D
1/2/26 19:02	12/31/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Saad Mark E	NY	D		1	S.d	-6,207	165.18	-38		10	D
1/2/26 18:49	1/2/26	XENE	Xenon Pharmaceuticals Inc.	A1	Health	Drug	Pharmaceutical Preparations	Mortimer Ian	A1	DO	P,CEO	3	S.dm	-2,924	44.78	-65		46	D
1/2/26 17:25	12/31/25	VRDN	Viridian Therapeutics, Inc.De	DE	Health	Drug	Pharmaceutical Preparations	Tousignant Jennifer	MA	O	GC	1	S	-71	31.16	-2	-100	0	D
1/2/26 17:13	12/30/25	SLRX	Salarius Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hanish Arnold C	TX	D		1	S	0	0.6296	0		5	M
1/2/26 16:19	12/16/25	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Goeltz II Robert C.	CA	O	CFO	4	S.m	-657	22.49	-29		92	D
1/2/26 16:15	12/31/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Amado Rafael	MA	O	See Rema	1	S.d	-188	17.43	-11		52	D
12/31/25 21:00	12/29/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Sukhatme Mayukh	X0	DO	P,CIO	2	S.dm	-29,522	21.74	-1,358		18,837	D
12/31/25 16:05	12/29/25	CVKD	Cadrenal Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Szot Matthew K	FL	O	CFO	2	S.m	-120	8.84	-14		10	D
12/30/25 17:54	12/23/25	ALZN	Alzamend Neuro, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ault Milton C III	NV	D		1	S	-4	2.07	-2		19	D
12/30/25 17:46	12/26/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ferrari Mauro	CA	D		2	S	-1,021	62.69	-16		69	D
12/30/25 16:17	12/30/25	MBIO	Mustang Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Herskowitz Neil	MA	D		1	S	0	0.9636	0		0	D
12/30/25 16:16	12/30/25	MBIO	Mustang Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chill Adam J.	MA	D		1	S	0	1.00	0		0	D
12/30/25 16:12	12/29/25	CTNM	Contineum Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Watkins Tim	CA	O	CMO,Head	1	S.d	-44	12.06	-4	-100	0	D
12/30/25 16:01	12/26/25	COGT	Cogent Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kearns Evan	MA	O	GC	1	S	-2,516	38.70	-65		109	D
12/30/25 16:01	12/26/25	COGT	Cogent Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Green John L.	MA	O	CFO	1	S	-2,978	38.68	-77		132	D
12/30/25 16:01	12/26/25	COGT	Cogent Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sachs Jessica	MA	O	Chief Me	1	S	-3,198	38.70	-83		134	D
12/30/25 16:01	12/26/25	COGT	Cogent Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Robinson John Edward	MA	O	Chief Sc	1	S	-3,487	38.74	-90		140	D
12/30/25 13:49	12/29/25	RARE	Ultragenyx Pharmaceutical Inc.	DE	Health	Drug	Pharmaceutical Preparations	Huizenga Theodore Alan	CA	O	SVP,Chie	1	S	-3	34.38	0	0	50	D
12/29/25 21:55	12/22/25	OLMA	Olema Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Harmon Cyrus	CA	D		1	S	-82	28.53	-3	0	858	D
12/29/25 21:11	12/24/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	Heerma Peter	CA	O	Chief Co	3	S	-475	35.88	-13		125	D
12/29/25 21:05	12/24/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	Rote William E.	CA	O	Chief Re	1	S.d	-2,406	40.10	-60		101	D
12/29/25 21:00	12/23/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Pulik Richard	X0	O	CFO	1	S.d	-9,122	22.43	-407		239	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

TC

Stat

Stk

Ins

Fil

+d

+w

+m

+q

+h

+y

avg

Filing Date

T Date

Ticker

Issuer

Inc

Sector

Ind

Industry

Owner

oSt

Rel

Title

#f

T

TVal

Price

L

Qty

oc

Own

H

r2y

r1y

r6m

r3m

r6w

r3w

r7d

r3d

f1d

f1w

f1m

f3m

f6m

f1y