Pharmaceutical Preparations Industry - Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	Title	T	TVal	Price	Qty	oc	Own	H
10/10/25 19:17	10/10/25	ZVRA	Zevra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McFarlane Neil F.	FL	DO	P,CEO	S.d	-211	10.82	-20	-8	222	D
10/10/25 18:45	10/8/25	LVTX	Lava Therapeutics Nv	P7	Health	Drug	Pharmaceutical Preparations	Cooperatieve Gilde Healthcare IV U.A.	P7	T		S.m	-198	1.56	-127	-2	5,294	D
10/10/25 18:17	9/12/25	BGMS	Bio Green Med Solution, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kua Khai Loon	N8	T		S.m	-267	5.65	-47	-12	338	D
10/10/25 18:16	10/8/25	BGMS	Bio Green Med Solution, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fitters Diversified Berhad	N8	T		S	-752	5.29	-142	-20	557	D
10/10/25 17:58	10/8/25	BYSI	Beyondspring Inc.		Health	Drug	Pharmaceutical Preparations	Decheng Capital China Life Sciences Usd Fund Iii, L.P.	CA	T		S.m	-25	1.78	-14	0	4,313	I
10/10/25 17:40	10/8/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kumar Neil	CA	DO	CEO	S.m	-4,383	54.79	-80	-1	5,697	I
10/10/25 17:33	10/9/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Khattar Jack A.	MD	DO	P,CEO	S.d	-3,029	50.57	-60	-3	2,212	D
10/10/25 17:23	10/9/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Raben David	MA	O	Chief Me	S.d	-406	18.45	-22	-38	35	D
10/10/25 17:22	10/9/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hyep Ivan	MA	O	CFO	S.d	-117	18.23	-6	-4	145	D
10/10/25 17:03	10/9/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	S.dm	-3,574	446.81	-8	-1	644	D
10/10/25 16:56	10/8/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Lee Chan Henry	V8	O	SVP,GC	S.d	-3,739	350.40	-11	-5	223	D
10/10/25 16:30	10/8/25	ALZN	Alzamend Neuro, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ault Milton C III	NV	D		S.dm	-295	2.42	-122	-85	21	I
10/10/25 16:21	10/9/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Newhall Charles W III	MD	D		S	-1,269	50.77	-25	-19	105	D
10/10/25 16:18	10/8/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Scadden David	MA	D		S.d	-8	41.00	0	-1	18	D
10/10/25 16:12	10/8/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kaye Edward M. Md	MA	D		S.d	-750	30.00	-25	-34	49	D
10/10/25 16:01	10/8/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	Anderman Todd	MA	O	GC	S	-137	12.34	-11	-11	88	D
10/10/25 16:00	10/9/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	Lilly Endowment Inc	IN	T		S	-9,038	852.49	-11	0	94,537	D
10/9/25 18:58	10/7/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rolph Timothy	CA	O	Chief Sc	S.d	-576	46.08	-13	-7	167	D
10/9/25 17:51	10/7/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Guyer William	CA	O	Chief De	S.d	-1,799	89.94	-20	-79	5	D
10/9/25 17:21	10/7/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Patel Anish	CO	O	COO	S	-134	20.10	-7	-2	277	I
10/9/25 16:22	8/19/25	HOOK	Hookipa Pharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	Peters Malte	NY	DO	CEO	S	-21	0.8217	-25	-32	54	D
10/9/25 16:07	10/7/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bitterman Kevin	MA	D		S.m	-6,313	70.14	-90	-8	972	I
10/9/25 16:00	10/8/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	Lilly Endowment Inc	IN	T		S	-86,235	850.28	-101	0	94,548	D
10/9/25 13:37	10/8/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Degnan Chris	NJ	O	CFO	S.d	-37	16.85	-2	-49	2	D
10/8/25 21:08	10/6/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tabuteau Herriot	NY	DOT	CEO	S.dm	-5,418	119.38	-45	-1	7,352	D
10/8/25 21:00	10/6/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Venker Eric	X0	O	P,Immuno	S.dm	-10,782	16.21	-665	-31	1,505	D
10/8/25 20:55	10/6/25	SPRB	Spruce Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Parkman Healthcare Partners LLC	CT	T		S	-5	19.14	0	-20	1	I
10/8/25 19:48	10/1/25	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hunter Heather	MI	O	SVP,COO	S	-3	1.19	-3	-2	135	D
10/8/25 19:08	10/6/25	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jarrett Jennifer	CA	O	COO	S.dm	-750	14.92	-50	-19	214	D
10/8/25 18:37	10/6/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Swayze Eric	CA	O	EVP Rese	S	-473	69.02	-7	-18	31	D
10/8/25 18:37	10/6/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	O'Neil Patrick R.	CA	O	EVP CLO,	S.d	-937	69.74	-13	-20	54	D
10/8/25 18:36	10/6/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Monia Brett P	CA	DO	CEO	S	-30	69.26	0	0	180	D
10/8/25 18:36	10/6/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Baroldi Joseph	CA	O	EVP,Chie	S	-113	69.37	-2	-5	33	D
10/8/25 17:37	10/6/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Piscitelli Dominic	CA	O	CFO	S.d	-160	14.52	-11	-19	48	D
10/8/25 17:35	10/6/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chacko Jacob	CA	DO	P,CEO	S	-462	12.32	-37	-7	531	D
10/8/25 17:33	10/6/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hyep Ivan	MA	O	CFO	S.dm	-553	18.21	-30	-17	145	D
10/8/25 17:33	10/6/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cohlhepp Ryan	MA	DO	P,COO	S.dm	-912	18.06	-51	-20	203	D
10/8/25 16:31	10/7/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	S.dm	-3,611	451.35	-8	-1	644	D
10/8/25 16:16	10/7/25	CARM	Carisma Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Klichinsky Michael	PA	O	Chief Sc	S.d	-14	0.2542	-57	-100	0	D
10/8/25 16:10	10/6/25	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	Taiwan Carbon Nano Technology Corp	F5	T		S	-25	3.59	-7	-1	1,037	D
10/8/25 16:00	10/7/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	Lilly Endowment Inc	IN	T		S	-22,722	848.01	-27	0	94,649	D
10/8/25 06:50	10/6/25	ALZN	Alzamend Neuro, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ault Milton C III	NV	D		S.dm	-344	2.47	-139	-63	82	I
10/7/25 20:22	10/6/25	CVKD	Cadrenal Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Szot Matthew K	FL	O	CFO	S	-1	13.99	0	-1	17	D
10/7/25 18:14	10/3/25	BYSI	Beyondspring Inc.		Health	Drug	Pharmaceutical Preparations	Decheng Capital China Life Sciences Usd Fund Iii, L.P.	CA	T		S.m	-36	1.78	-20	0	4,327	I
10/7/25 17:08	10/7/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Malik Fady Ibraham	CA	O	EVP Rese	S.d	-121	60.56	-2	-1	141	D
10/7/25 17:00	10/3/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Booth Bruce	MA	D		S.m	-1,486	29.99	-50	-1	3,566	I
10/7/25 16:32	10/6/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Benkowitz Michael	MD	O	P,COO	S.d	-10,130	450.24	-23	-89	3	I
10/7/25 16:26	10/3/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kaye Edward M. Md	MA	D		S	-1,065	25.09	-42	-46	49	D
10/7/25 16:26	10/3/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Allan Jonathan	MA	O	GC,Corp	S.d	-251	25.07	-10	-46	12	D
10/7/25 16:11	10/3/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mosbrooker Eric	CA	O	Chief Co	S.d	-298	45.38	-7	-11	55	D
10/7/25 16:00	10/6/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	Lilly Endowment Inc	IN	T		S	-137,042	850.22	-161	0	94,676	D
10/6/25 17:54	10/2/25	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	Taiwan Carbon Nano Technology Corp	F5	T		S	-7	3.59	-2	0	1,044	D
10/6/25 17:35	10/3/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	S.dm	-3,584	447.95	-8	-1	644	D
10/6/25 17:13	10/2/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	Kaiser Peter	MA	O	Chief De	S	-106	11.03	-10	-5	194	D
10/6/25 17:10	10/2/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	Heier Jeffrey S.	MA	O	Chief Sc	S	-116	11.04	-11	-4	249	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Lee Kevin	X0	DO	CEO	S.m	-46	8.41	-5	-1	475	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Skynner Michael	X0	O	CTO	S.m	-15	8.41	-2	-2	118	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Milnes Alistair	X0	O	COO	S.m	-18	8.40	-2	-2	93	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Hannay Michael Charles Ferguson	X0	O	CHIEF PR	S.m	-6	8.40	-1	-1	53	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Young Alethia	X0	O	CFO	S	-4	8.51	0	-1	45	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Thompson Travis Alvin	X0	O	Chief Ac	S.m	-3	8.40	0	-1	31	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Swanton Robert Charles	X0	D		S	-1	8.55	0	-1	15	D
10/6/25 16:27	10/6/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Kaye Edward M. Md	CA	D		S	-405	60.00	-7	-41	10	D
10/6/25 16:00	10/3/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	Lilly Endowment Inc	IN	T		S	-161,220	837.93	-192	0	94,837	D
10/6/25 15:15	10/2/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Edwards Larry Todd	CA	O	See Rema	S	-90	20.04	-5	-2	179	D
10/3/25 21:58	10/2/25	ELTP	Elite Pharmaceuticals Inc /Nv/	NJ	Health	Drug	Pharmaceutical Preparations	Plassche Douglas	NJ	O	EVP Oper	S	-499	0.6240	-800	-19	3,500	D
10/3/25 21:35	10/1/25	ALZN	Alzamend Neuro, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ault Milton C III	NV	D		S.dm	-297	2.41	-123	-85	21	I
10/3/25 21:27	10/1/25	JAZZ	Jazz Pharmaceuticals Plc	L2	Health	Drug	Pharmaceutical Preparations	Cozadd Bruce C	L2	D		S.m	-754	137.01	-6	-1	409	D
10/3/25 20:24	10/2/25	CVKD	Cadrenal Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pham Quang X	FL	DOT	CEO,CB	S	-7	14.13	-1	0	402	D
10/3/25 18:15	10/1/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hamilton James C	CA	O	Chief Me	S	-700	35.00	-20	-9	212	D
10/3/25 17:25	10/1/25	CARM	Carisma Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Klichinsky Michael	PA	O	Chief Sc	S.m	-124	0.2567	-484	-100	0	D
10/3/25 17:24	10/1/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Belanoff Joseph K	CA	DO	CEO	S	-3,403	85.08	-40	-1	2,781	I
10/3/25 17:17	10/1/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Lyon Joseph Douglas	CA	O	See Rema	S.d	-424	84.75	-5	-33	10	D
10/3/25 17:15	10/1/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Maduck Sean	CA	O	See Rema	S.d	-1,701	85.06	-20	-15	118	D
10/3/25 17:14	10/2/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Poulton Jeffrey V.	MA	O	EVP,CFO	S	-1,727	452.05	-4	-7	54	D
10/3/25 17:14	10/2/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Greenstreet Yvonne	MA	DO	CEO	S	-4,034	452.05	-9	-12	66	D
10/3/25 17:14	10/2/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Tanguler Tolga	MA	O	EVP,Chie	S	-635	452.05	-1	-5	27	D
10/3/25 17:13	10/2/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Fitzgerald Kevin Joseph	MA	O	CSO,EVP,	S	-1,103	452.05	-2	-9	26	D
10/3/25 17:12	10/2/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Garg Pushkal	MA	O	EVP Chie	S.m	-2,692	451.76	-6	-22	21	D
10/3/25 17:02	10/1/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Watanabe Todd	CA	DO	See Rema	S.m	-885	19.66	-45	-4	1,080	D
10/3/25 17:01	10/1/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Welgus Howard G.	CA	D		S.d	-189	18.92	-10	-9	100	D
10/3/25 16:56	10/1/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Abate Kristin	MA	O	Chief Ac	S	-2	6.30	0	-3	10	D
10/3/25 16:45	10/1/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Kozarich John W	FL	D		S	-84	179.44	0	-1	45	D
10/3/25 16:41	10/1/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pizzuti Dana	CA	O	Chief Me	S.d	-209	41.81	-5	-7	66	D
10/3/25 16:30	10/1/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Young Jonathan	CA	O	COO	S.d	-597	47.76	-13	-5	257	D
10/3/25 16:28	10/1/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Balcom Alexandra	MA	O	CFO	S.d	-1,710	85.48	-20	-24	62	D
10/3/25 16:25	10/1/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ticho Barry	MA	O	Chief Me	S	-126	23.64	-5	-29	13	D
10/3/25 16:20	10/2/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Chen Yajing	MA	O	CFO	S.d	-16	34.25	0	-3	17	D
10/3/25 16:18	10/2/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Khattar Jack A.	MD	DO	P,CEO	S.d	-92	48.06	-2	0	2,167	D
10/3/25 16:07	10/2/25	VRTX	Vertex Pharmaceuticals Inc / Ma	MA	Health	Drug	Pharmaceutical Preparations	Biller Jonathan	MA	O	EVP,GC	S	-281	404.21	-1	-4	16	D
10/3/25 16:00	10/2/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	Lilly Endowment Inc	IN	T		S	-92,503	821.55	-113	0	95,029	D
10/2/25 20:51	9/30/25	BYSI	Beyondspring Inc.		Health	Drug	Pharmaceutical Preparations	Decheng Capital China Life Sciences Usd Fund Iii, L.P.	CA	T		S.m	-14	1.80	-8	0	4,347	I
10/2/25 19:36	10/1/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Wender Joseph H	CA	D		S	-1,100	65.50	-17	-15	92	I
10/2/25 19:36	10/1/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Swayze Eric	CA	O	EVP Rese	S.dm	-1,794	66.16	-27	-42	37	D
10/2/25 19:35	10/2/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	O'Neil Patrick R.	CA	O	EVP CLO,	S.d	-4,377	67.69	-65	-53	57	D
10/2/25 19:35	10/2/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Baroldi Joseph	CA	O	EVP,Chie	S.d	-1,020	68.01	-15	-30	35	D
10/2/25 19:24	10/1/25	TERN	Terns Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kuriakose Emil	CA	O	Chief Me	S	-7	7.85	-1	-2	52	D
10/2/25 19:18	9/30/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chacko Jacob	CA	DO	P,CEO	S.m	-1,054	12.04	-88	-13	569	D
10/2/25 17:04	10/1/25	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Petersen Floyd F.	CA	D		S	-14	27.20	-1	-1	76	D
10/2/25 16:56	10/1/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	Lilly Endowment Inc	IN	T		S	-177,290	821.47	-216	0	95,142	D
10/2/25 16:55	10/1/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	Lilly Endowment Inc	IN	T		S	-107,363	794.15	-135	0	95,358	D
10/2/25 16:47	9/30/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Baker Bros. Advisors LP	NY	H	Former 1	S.m	-1,057	1.45	-730	-63	425	I
10/2/25 16:30	10/1/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	S.dm	-3,441	430.17	-8	-1	644	D
10/2/25 16:30	10/2/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	S.d	-4,803	436.60	-11	-23	37	D
10/2/25 16:15	9/30/25	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Klee Justin B.	MA	DO	Co-CEO	S	-431	14.38	-30	-1	3,325	D
10/2/25 16:15	9/30/25	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mazzariello Gina	MA	O	GC	S	-129	14.58	-9	-6	148	D
10/2/25 16:15	9/30/25	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Frates James M	MA	O	CFO	S	-155	14.65	-11	-3	307	D
10/2/25 16:15	9/30/25	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cohen Joshua B	MA	DO	Co-CEO	S	-429	14.35	-30	-1	3,325	D
10/2/25 16:15	9/30/25	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bedrosian Camille L	MA	O	Chief Me	S	-176	14.58	-12	-6	182	D
10/2/25 16:10	9/30/25	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	Taiwan Carbon Nano Technology Corp	F5	T		S.m	-9	3.48	-3	0	1,046	D
10/2/25 16:03	9/30/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Scadden David	MA	D		S.d	-8	40.00	0	-1	18	D
10/2/25 16:02	10/1/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Khattar Jack A.	MD	DO	P,CEO	S.d	-1,931	48.07	-40	-2	2,166	D
10/2/25 16:02	9/30/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dunlop A. Sinclair	MA	D		S	-702	22.58	-31	-14	189	I
10/1/25 20:17	9/29/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Balcom Alexandra	MA	O	CFO	S.dm	-2,346	85.05	-28	-31	62	D
10/1/25 20:14	9/29/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Noci Darlene	MA	O	Chief De	S.d	-332	83.07	-4	-8	48	D
10/1/25 19:17	10/1/25	XENE	Xenon Pharmaceuticals Inc.	A1	Health	Drug	Pharmaceutical Preparations	Mortimer Ian	A1	DO	P,CEO,IN	S.d	-1,004	40.16	-25	-35	46	D
10/1/25 18:04	9/29/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Booth Bruce	MA	D		S.m	-2,367	30.08	-79	-2	3,615	I
10/1/25 17:47	9/29/25	CVKD	Cadrenal Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Szot Matthew K	FL	O	CFO	S.m	-25	13.99	-2	-10	17	D
10/1/25 17:46	9/29/25	CVKD	Cadrenal Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pham Quang X	FL	DOT	CEO,CB	S.m	-18	14.01	-1	0	403	D
10/1/25 17:22	9/29/25	MLTX	Moonlake Immunotherapeutics	E9	Health	Drug	Pharmaceutical Preparations	Chen Bihua	MA	H	Former 1	S.m	-46,868	7.21	-6,500	-77	1,994	I
10/1/25 17:16	9/29/25	PGEN	Precigen, Inc.	VA	Health	Drug	Pharmaceutical Preparations	Kindler Jeffrey B	MD	D		S.m	-604	3.47	-174	-34	346	D
10/1/25 16:57	9/29/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Meisner Lara	MA	O	GC	S.d	-499	14.75	-34	-100	0	D
10/1/25 16:55	9/29/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	O'Neil Patrick R.	CA	O	EVP CLO,	S.dm	-1,635	64.62	-25	-31	57	D
10/1/25 16:55	9/30/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Geary Richard S	CA	O	EVP,Chie	S.d	-3,778	65.24	-58	-42	80	D
10/1/25 16:46	9/29/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hohl Benjamin	CO	O	CFO	S.d	-66	20.40	-3	-12	23	D
10/1/25 16:44	9/29/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Tessari Eben	X0	O	COO	S.d	-1,610	38.33	-42	-55	35	D
10/1/25 16:31	9/29/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Benkowitz Michael	MD	O	P,COO	S.d	-9,491	421.80	-23	-89	3	I
10/1/25 16:30	9/29/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	O'Malley Brendan M.	OH	O	SVP,GC	S	-51	5.39	-9	-3	351	D
10/1/25 16:30	9/29/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Seshadri Vishwas	OH	DO	CEO	S.m	-235	5.31	-44	-4	1,190	D
10/1/25 16:30	9/29/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Vazzano Joseph Walter	OH	O	CFO	S	-49	5.39	-9	-2	454	D
10/1/25 16:26	10/1/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Blum Robert I	CA	DO	P,CEO	S	-275	55.05	-5	-1	372	D
10/1/25 16:24	10/1/25	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chole Timothy	MI	O	SVP,CCO	S	-3	1.19	-3	-2	125	D
10/1/25 16:23	10/1/25	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Neri Jesse	MI	O	SVP,CFO	S	-1	1.19	-1	-1	126	D
10/1/25 16:22	10/1/25	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Strobeck Mark	MI	DO	P,CEO	S	-8	1.19	-7	-2	331	D
10/1/25 16:20	9/30/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Khattar Jack A.	MD	DO	P,CEO	S.d	-414	48.25	-9	0	2,153	D
10/1/25 16:10	9/30/25	PAHC	Phibro Animal Health Corp	DE	Health	Drug	Pharmaceutical Preparations	Bendheim Jack	NJ	DOT	P,CEO	S	-834	40.38	-21	-26	58	I
10/1/25 16:00	9/30/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Loumeau Eric J	CA	O	GC	S.d	-239	29.00	-8	-48	9	D
10/1/25 16:00	9/30/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	Lilly Endowment Inc	IN	T		S	-86,793	763.39	-114	0	95,493	D
10/1/25 08:00	9/29/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	S.dm	-3,394	424.24	-8	-1	644	D
9/30/25 19:15	9/26/25	ALZN	Alzamend Neuro, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ault Milton C III	NV	DT		S.m	-184	2.31	-80	-64	45	I
9/30/25 18:59	9/29/25	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Azoy Alexander	CA	O	Chief Ac	S	-37	13.00	-3	-9	27	D
9/30/25 17:56	9/26/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jones Cecilia	MA	O	CFO	S.d	-134	36.77	-4	-10	34	D
9/30/25 17:53	9/26/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lyssikatos Joseph P	CO	O	CHIEF SC	S	-81	20.25	-4	0	928	I
9/30/25 17:51	9/26/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kintz Samuel	CO	DO	P,CEO	S	-74	20.06	-4	0	915	I
9/30/25 17:44	9/30/25	PGEN	Precigen, Inc.	VA	Health	Drug	Pharmaceutical Preparations	Kirk Randal J	VA	DT		S	-6,171	3.41	-1,810	-1	126,913	I
9/30/25 16:42	9/26/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Struthers Richard Scott	CA	DO	P,CEO	S	-180	45.00	-4	0	1,298	I
9/30/25 16:41	9/26/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fust Matthew K	CA	D		S.d	-716	44.75	-16	-41	23	D
9/30/25 16:33	9/30/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Kaye Edward M. Md	CA	D		S	-369	55.08	-7	-29	17	D
9/30/25 16:24	9/29/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Khattar Jack A.	MD	DO	P,CEO	S.d	-491	48.02	-10	0	2,150	D
9/30/25 16:09	9/26/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cloonan Michael	MA	DO	P,CEO	S.dm	-728	29.11	-25	-4	547	D
9/29/25 20:06	9/25/25	BYSI	Beyondspring Inc.		Health	Drug	Pharmaceutical Preparations	Decheng Capital China Life Sciences Usd Fund Iii, L.P.	CA	T		S.m	-3	1.69	-2	0	4,355	I
9/29/25 19:30	9/29/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Powl Brian T.	CA	O	Chief Co	S	-80	8.94	-9	-8	100	D
9/29/25 19:30	9/29/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bair Teresa Brophy	CA	O	GC	S	-79	8.94	-9	-6	148	D
9/29/25 19:30	9/29/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ford Kathleen	CA	O	COO	S	-62	8.94	-7	-10	63	D
9/29/25 19:30	9/29/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Leoni Mollie	CA	O	Chief Me	S	-110	8.94	-12	-7	158	D
9/29/25 19:30	9/29/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Wilson Troy Edward	CA	DO	P,CEO	S	-327	8.94	-37	-4	826	D
9/29/25 19:30	9/29/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Doyle Thomas James	CA	O	SVP,Fina	S	-41	8.94	-5	-4	110	D
9/29/25 16:26	9/26/25	AQST	Aquestive Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Barber Daniel	NJ	DO	P,CEO	S	-551	6.03	-91	-9	923	D
9/29/25 16:26	9/26/25	AQST	Aquestive Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Boyd Peter E.	NJ	O	See Rema	S	-63	6.30	-10	-3	278	D
9/29/25 16:15	9/25/25	TNGX	Tango Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Third Rock Ventures Iv, L.P.	MA	T		S	-4,009	8.02	-500	-3	13,864	D
9/29/25 07:41	9/25/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	S.dm	-3,437	429.58	-8	-1	644	D
9/26/25 20:36	9/24/25	CVKD	Cadrenal Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Szot Matthew K	FL	O	CFO	S.m	-174	14.05	-12	-40	19	D
9/26/25 20:35	9/24/25	CVKD	Cadrenal Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pham Quang X	FL	DOT	CEO,CB	S.m	-132	14.06	-9	-2	404	D
9/26/25 19:43	9/24/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Kapusta Matthew C	P7	DO	CEO,MD	S.d	-9,382	41.46	-226	-26	651	D
9/26/25 19:37	9/24/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Klemt Christian	P7	O	CFO	S.dm	-945	52.51	-18	-8	218	D
9/26/25 15:53	9/24/25	MNPR	Monopar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	Tactic Pharma LLC	IL	T		S	-35,000	63.61	-550	-67	272	D
9/25/25 20:59	9/23/25	ALZN	Alzamend Neuro, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ault Milton C III	NV	DT		S.dm	-227	2.34	-97	-44	124	I
9/25/25 19:44	9/23/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lyssikatos Joseph P	CO	O	CHIEF SC	S	-30	20.03	-2	0	932	I
9/25/25 19:42	9/23/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kintz Samuel	CO	DO	P,CEO	S	-56	20.03	-3	0	919	I
9/25/25 16:31	9/24/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Causey Christopher	MD	D		S.d	-440	440.00	-1	-17	5	D
9/25/25 16:30	9/23/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	S.dm	-3,409	426.14	-8	-1	644	D
9/24/25 20:35	9/22/25	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	Waddill William D.	CA	D		S	-257	64.25	-4	-44	5	D
9/24/25 19:42	9/22/25	OKUR	Onkure Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Saccomano Nicholas A	CO	DO	P,CEO	S	0	2.62	0	-2	4	D
9/24/25 19:41	9/22/25	OKUR	Onkure Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Leverone Jason A.	CO	O	CFO	S	-1	2.62	0	-2	13	D
9/24/25 19:00	9/24/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	Bush Tia L	X0	O	Chief Te	S.d	-840	24.00	-35	-22	122	D
9/24/25 18:49	9/22/25	BYSI	Beyondspring Inc.		Health	Drug	Pharmaceutical Preparations	Decheng Capital China Life Sciences Usd Fund Iii, L.P.	CA	T		S.m	-21	1.76	-12	0	4,357	I
9/24/25 17:11	9/23/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Aryeh Jason	FL	D		S	-1,708	170.81	-10	-7	126	D
9/24/25 16:30	9/22/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chacko Jacob	CA	DO	P,CEO	S	-1,350	10.80	-125	-16	656	D
9/24/25 16:30	9/22/25	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	Calkins Daniel	MA	O	CFO	S.m	-1	9.13	0	0	110	D
9/24/25 16:14	9/23/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Khattar Jack A.	MD	DO	P,CEO	S.d	-1,394	47.23	-30	-1	2,146	D
9/24/25 16:05	9/22/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	Reed Elizabeth E	CA	O	GC,GC	S.d	-250	25.00	-10	-10	90	D
9/24/25 06:35	9/22/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Benkowitz Michael	MD	O	P,COO	S.d	-9,368	416.35	-23	-89	3	I
9/23/25 21:00	9/19/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Venker Eric	X0	O	P,Immuno	S.dm	-25,525	14.92	-1,711	-53	1,505	D
9/23/25 17:32	9/22/25	XOMA	Xoma Royalty Corp	NV	Health	Drug	Pharmaceutical Preparations	Burns Thomas M.	CA	O	SVP,Fina	S.d	-156	35.99	-4	-10	40	D
9/23/25 17:14	9/19/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lyssikatos Joseph P	CO	O	CHIEF SC	S	-136	19.39	-7	-1	933	I
9/23/25 17:07	9/23/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Malik Fady Ibraham	CA	O	EVP Rese	S.d	-99	49.28	-2	-1	141	D
9/23/25 16:57	9/22/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hughes Steven George	CA	O	Chief Me	S.d	-90	40.58	-2	-5	39	D
9/23/25 16:33	9/19/25	LVTX	Lava Therapeutics Nv	P7	Health	Drug	Pharmaceutical Preparations	Versant Venture Capital Vi, L.P.	CA	T		S	-4,069	1.40	-2,903	-100	0	M
9/23/25 16:30	9/19/25	ALZN	Alzamend Neuro, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ault Milton C III	NV	DT		S.d	-181	2.35	-77	-39	121	I
9/23/25 16:22	9/22/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Khattar Jack A.	MD	DO	P,CEO	S.d	-780	47.02	-17	-1	2,128	D
9/22/25 19:49	9/22/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	O'Malley Brendan M.	OH	O	SVP,GC	S	-4	5.43	-1	0	360	D
9/22/25 19:00	9/22/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jacobson Mark L.	NY	O	COO	S.d	-1,160	115.96	-10	-100	0	D
9/22/25 18:32	9/18/25	PAHC	Phibro Animal Health Corp	DE	Health	Drug	Pharmaceutical Preparations	Bendheim Jack	NJ	DOT	P,CEO	S.d	-283	40.26	-7	-8	78	I
9/22/25 17:25	9/19/25	AQST	Aquestive Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Barber Daniel	NJ	DO	P,CEO	S	-2	6.00	0	0	1,015	D
9/22/25 17:14	9/19/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Davis Krista	MN	O	SVP,CHRO	S	-98	98.04	-1	-2	60	D
9/22/25 16:39	9/19/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	S.dm	-3,314	414.19	-8	-1	644	D
9/22/25 16:00	9/19/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	Lilly Endowment Inc	IN	T		S	-18,059	763.10	-24	0	95,607	D
9/19/25 21:17	9/19/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dunlop A. Sinclair	MA	D		S	-714	22.95	-31	-12	223	I
9/19/25 20:46	9/18/25	PGEN	Precigen, Inc.	VA	Health	Drug	Pharmaceutical Preparations	Kirk Randal J	VA	DT		S.dm	-18,654	3.73	-5,000	-4	128,722	I
9/19/25 19:12	9/17/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kintz Samuel	CO	DO	P,CEO	S.m	-116	19.29	-6	-1	922	I

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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