Pharmaceutical Preparations Industry - Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	Title	#f	T	TVal	Price	Qty	oc	Own	H
10/10/25 20:06	10/8/25	ACET	Adicet Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	T		3	P.d	11,372	0.9632	11,806	447	14,447	I
10/10/25 19:48	10/8/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Graham G. Walmsley	CA	D		1	M.d	1,866	20.55	91	8	1,293	D
10/10/25 19:17	10/10/25	ZVRA	Zevra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McFarlane Neil F.	FL	DO	P,CEO	2	M.d	211	3.03	70	46	222	D
10/10/25 19:17	10/10/25	ZVRA	Zevra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McFarlane Neil F.	FL	DO	P,CEO	2	S.d	-211	3.03	-70		222	D
10/10/25 18:45	10/8/25	LVTX	Lava Therapeutics Nv	P7	Health	Drug	Pharmaceutical Preparations	Cooperatieve Gilde Healthcare IV U.A.	P7	T		1	S.m	-198	1.56	-127		5,294	D
10/10/25 18:17	9/12/25	BGMS	Bio Green Med Solution, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kua Khai Loon	N8	T		2	S.m	-400	6.04	-66		385	D
10/10/25 18:16	10/8/25	BGMS	Bio Green Med Solution, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fitters Diversified Berhad	N8	T		1	S	-752	5.29	-142		557	D
10/10/25 17:58	9/12/25	BYSI	Beyondspring Inc.		Health	Drug	Pharmaceutical Preparations	Decheng Capital China Life Sciences Usd Fund Iii, L.P.	CA	T		15	S.m	-1,533	2.69	-569		4,488	I
10/10/25 17:40	9/4/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kumar Neil	CA	DO	CEO	5	S.dm	-13,503	40.81	-331		5,883	I
10/10/25 17:33	10/9/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Khattar Jack A.	MD	DO	P,CEO	27	M.dm	30,079	29.33	1,025	86	2,212	D
10/10/25 17:33	10/9/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Khattar Jack A.	MD	DO	P,CEO	27	S.dm	-30,079	29.33	-1,025		2,212	D
10/10/25 17:23	10/9/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Raben David	MA	O	Chief Me	2	M.d	489	11.12	44		35	D
10/10/25 17:23	10/9/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Raben David	MA	O	Chief Me	2	S.d	-489	11.12	-44		35	D
10/10/25 17:22	10/9/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hyep Ivan	MA	O	CFO	4	M.dm	810	11.00	74	103	145	D
10/10/25 17:22	10/9/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hyep Ivan	MA	O	CFO	4	S.dm	-810	11.00	-74		145	D
10/10/25 17:03	10/9/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	26	M.dm	54,188	270.94	200	45	644	D
10/10/25 17:03	10/9/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Rothblatt Martine A	MD	DO	CHAIRPER	26	S.dm	-54,188	270.94	-200		644	D
10/10/25 16:56	10/8/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Lee Chan Henry	V8	O	SVP,GC	7	S.d	-15,820	266.81	-59		266	D
10/10/25 16:56	10/8/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Lee Chan Henry	V8	O	SVP,GC	7	M.d	15,820	266.81	59	29	266	D
10/10/25 16:30	10/8/25	ALZN	Alzamend Neuro, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ault Milton C III	NV	D		10	S.dm	-2,212	2.44	-905		124	I
10/10/25 16:21	10/9/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Newhall Charles W III	MD	D		4	S	-1,539	49.65	-31		134	D
10/10/25 16:18	10/8/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Scadden David	MA	D		8	M.d	116	29.10	4	29	18	D
10/10/25 16:18	10/8/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Scadden David	MA	D		8	S.d	-116	29.10	-4		18	D
10/10/25 16:12	10/8/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kaye Edward M. Md	MA	D		9	M.dm	4,409	20.71	213		189	D
10/10/25 16:12	10/8/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kaye Edward M. Md	MA	D		9	S.dm	-4,409	20.71	-213		189	D
10/10/25 16:01	10/8/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	Anderman Todd	MA	O	GC	1	S	-137	12.34	-11		88	D
10/10/25 16:00	7/24/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	Lilly Endowment Inc	IN	T		12	S	-1,205,217	814.34	-1,480		95,737	D
10/9/25 18:58	9/8/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rolph Timothy	CA	O	Chief Sc	7	M.d	2,576	34.10	76	83	167	D
10/9/25 18:58	9/8/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rolph Timothy	CA	O	Chief Sc	7	S.d	-2,576	34.10	-76		167	D
10/9/25 18:58	10/8/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cheng Andrew	CA	DO	P,CEO	4	M.dm	2,985	23.15	129	32	526	D
10/9/25 17:51	10/7/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Guyer William	CA	O	Chief De	10	M.dm	7,810	48.88	160		5	D
10/9/25 17:51	10/7/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Guyer William	CA	O	Chief De	10	S.dm	-7,810	48.88	-160		5	D
10/9/25 17:24	10/7/25	ZBIO	Zenas Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Moulder Leon O Jr	MA	DO	See Rema	1	P	770	20.85	37	2	1,975	I
10/9/25 17:21	10/7/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Patel Anish	CO	O	COO	3	S	-391	19.53	-20		290	I
10/9/25 16:22	8/19/25	HOOK	Hookipa Pharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	Peters Malte	NY	DO	CEO	2	S	-48	0.8745	-54		80	D
10/9/25 16:15	10/7/25	ZBIO	Zenas Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fairmount Funds Management LLC	PA	D		1	P	6,008	19.00	316	17	2,209	I
10/9/25 16:07	10/7/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bitterman Kevin	MA	D		7	S.m	-11,618	65.68	-177		1,148	I
10/9/25 15:37	9/13/24	ZBIO	Zenas Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lu Hongbo	MA	D		1	P.m	6,000	18.63	322		322	I
10/9/25 13:37	10/8/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Degnan Chris	NJ	O	CFO	2	M.d	37	5.55	7		2	D
10/9/25 13:37	10/8/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	Degnan Chris	NJ	O	CFO	2	S.d	-37	5.55	-7		2	D
10/9/25 09:01	10/8/25	MLTX	Moonlake Immunotherapeutics	E9	Health	Drug	Pharmaceutical Preparations	Bodenstedt Matthias	V8	O	CFO	1	P	99	9.09	11	2	628	D
10/8/25 21:08	10/6/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tabuteau Herriot	NY	DOT	CEO	4	M.dm	13,648	63.03	217	3	7,352	D
10/8/25 21:08	10/6/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tabuteau Herriot	NY	DOT	CEO	4	S.dm	-13,648	63.03	-217		7,352	D
10/8/25 21:00	10/6/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Venker Eric	X0	O	P,Immuno	8	M.dm	51,372	10.27	5,004		1,654	D
10/8/25 21:00	10/6/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Venker Eric	X0	O	P,Immuno	8	S.dm	-51,372	10.27	-5,004		1,654	D
10/8/25 20:55	10/6/25	SPRB	Spruce Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Parkman Healthcare Partners LLC	CT	T		2	P	10	18.53	1	96	1	I
10/8/25 20:55	10/6/25	SPRB	Spruce Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Parkman Healthcare Partners LLC	CT	T		2	S	-10	18.53	-1		1	I
10/8/25 19:48	10/1/25	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hunter Heather	MI	O	SVP,COO	1	S	-3	1.19	-3		135	D
10/8/25 19:08	10/6/25	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jarrett Jennifer	CA	O	COO	2	M.dm	812	8.07	101	89	214	D
10/8/25 19:08	10/6/25	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jarrett Jennifer	CA	O	COO	2	S.dm	-812	8.07	-101		214	D
10/8/25 18:37	10/6/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Swayze Eric	CA	O	EVP Rese	4	S.dm	-4,277	59.24	-72		37	D
10/8/25 18:37	10/6/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	O'Neil Patrick R.	CA	O	EVP CLO,	12	M.dm	25,027	58.37	429		57	D
10/8/25 18:37	10/6/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	O'Neil Patrick R.	CA	O	EVP CLO,	12	S.dm	-25,027	58.37	-429		57	D
10/8/25 18:36	10/6/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Monia Brett P	CA	DO	CEO	6	S.d	-21,594	52.15	-414		180	D
10/8/25 18:36	10/6/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Baroldi Joseph	CA	O	EVP,Chie	9	S.d	-5,745	47.24	-122		35	D
10/8/25 17:37	10/6/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Piscitelli Dominic	CA	O	CFO	2	M.d	208	9.44	22	84	48	D
10/8/25 17:37	10/6/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Piscitelli Dominic	CA	O	CFO	2	S.d	-208	9.44	-22		48	D
10/8/25 17:35	10/6/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chacko Jacob	CA	DO	P,CEO	3	S.m	-2,865	11.46	-250		656	D
10/8/25 17:33	10/6/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cohlhepp Ryan	MA	DO	P,COO	2	M.dm	1,033	12.52	83	69	203	D
10/8/25 17:33	10/6/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cohlhepp Ryan	MA	DO	P,COO	2	S.dm	-1,033	12.52	-83		203	D
10/8/25 16:58	10/4/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Megna Michael R	X0	O	CHIEF AC	5	M.dm	1,394	21.19	66		38	D
10/8/25 16:45	10/7/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Fisher Andrew	X0	O	GC	3	M.d	126	0.1309	962		418	D
10/8/25 16:44	10/7/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Zaccardelli David	X0	DO	P,CEO	3	M.d	2,746	0.7323	3,750	39	13,376	D
10/8/25 16:43	10/7/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Rickard Kathleen A.	X0	O	Chief Me	3	M.d	767	0.6079	1,261	94	2,607	D
10/8/25 16:42	10/7/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Hahn Mark W	X0	O	CFO	3	M.d	2,746	0.7323	3,750	43	12,465	D
10/8/25 16:41	10/7/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Austwick Michael	X0	D		3	M.d	148	1.38	107		13	D
10/8/25 16:40	10/7/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Ullman Anders	X0	D		2	M.d	0	0.00	96	37	359	D
10/8/25 16:38	10/7/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Shah Mahendra	X0	D		3	M.d	47	0.4761	100		93	D
10/8/25 16:36	10/7/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Sinha Vikas	X0	D		3	M.d	57	0.5670	100		94	D
10/8/25 16:35	10/7/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Deschamps Lisa	X0	D		3	M.d	124	1.18	105		85	D
10/8/25 16:34	10/7/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Ebsworth David R	X0	D		3	M.d	25	0.2556	98	7	1,498	M
10/8/25 16:33	10/7/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Edwards Martin	X0	D		3	M.d	142	1.33	107	209	158	D
10/8/25 16:32	10/7/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Brady James Aloysius	X0	D		3	M.d	11	0.1119	97		23	D
10/8/25 16:31	10/7/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Cunningham Kenneth	X0	D		3	M.d	142	1.33	107		80	D
10/8/25 16:30	10/7/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Ackermann Christina	X0	D		3	M.d	24	0.2430	98		64	D
10/8/25 16:16	10/7/25	CARM	Carisma Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Klichinsky Michael	PA	O	Chief Sc	3	M.dm	145	0.2425	598		0	D
10/8/25 16:16	10/7/25	CARM	Carisma Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Klichinsky Michael	PA	O	Chief Sc	3	S.dm	-145	0.2425	-598	-100	0	D
10/8/25 16:10	8/5/25	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	Taiwan Carbon Nano Technology Corp	F5	T		5	S.m	-167	2.94	-57		1,080	D
10/7/25 20:22	10/6/25	CVKD	Cadrenal Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Szot Matthew K	FL	O	CFO	4	S.m	-229	14.03	-16		31	D
10/7/25 17:08	9/9/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Malik Fady Ibraham	CA	O	EVP Rese	12	M.d	674	28.07	24	21	141	D
10/7/25 17:08	9/9/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Malik Fady Ibraham	CA	O	EVP Rese	12	S.d	-674	28.07	-24		141	D
10/7/25 17:00	10/3/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Booth Bruce	MA	D		2	S.m	-3,853	30.05	-128		3,615	I
10/7/25 16:32	10/6/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Benkowitz Michael	MD	O	P,COO	12	M.dm	74,749	290.00	258		3	I
10/7/25 16:32	10/6/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Benkowitz Michael	MD	O	P,COO	12	S.dm	-74,749	290.00	-258		3	I
10/7/25 16:26	10/3/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Allan Jonathan	MA	O	GC,Corp	7	M.dm	1,094	14.88	74		26	D
10/7/25 16:26	10/3/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Allan Jonathan	MA	O	GC,Corp	7	S.dm	-1,094	14.88	-74		26	D
10/7/25 16:11	10/3/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mosbrooker Eric	CA	O	Chief Co	6	M.d	7,618	27.04	282		55	D
10/7/25 16:11	10/3/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mosbrooker Eric	CA	O	Chief Co	6	S.d	-7,618	27.04	-282		55	D
10/7/25 08:56	10/3/25	IMRX	Immuneering Corp	DE	Health	Drug	Pharmaceutical Preparations	Feinberg Peter	MA	D		3	P	139	6.93	20	2	1,141	D
10/7/25 07:05	10/4/25	PRLD	Prelude Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Huang Jane	DE	O	P,CMO	1	M.d	0	0.00	9	12	87	D
10/6/25 17:22	10/2/25	BMY	Bristol Myers Squibb Co	DE	Health	Drug	Pharmaceutical Preparations	Gallman Cari	NJ	O	EVP,GC	2	M.d	0	0.00	6	103	11	D
10/6/25 17:13	10/2/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	Kaiser Peter	MA	O	Chief De	2	S	-143	11.27	-13		204	D
10/6/25 17:10	10/2/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	Heier Jeffrey S.	MA	O	Chief Sc	2	S	-153	11.27	-14		260	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Lee Kevin	X0	DO	CEO	1	S.m	-46	8.41	-5		475	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Skynner Michael	X0	O	CTO	1	S.m	-15	8.41	-2		118	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Milnes Alistair	X0	O	COO	1	S.m	-18	8.40	-2		93	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Hannay Michael Charles Ferguson	X0	O	CHIEF PR	1	S.m	-6	8.40	-1		53	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Young Alethia	X0	O	CFO	1	S	-4	8.51	0		45	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Thompson Travis Alvin	X0	O	Chief Ac	1	S.m	-3	8.40	0		31	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Swanton Robert Charles	X0	D		1	S	-1	8.55	0		15	D
10/6/25 15:15	10/2/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Edwards Larry Todd	CA	O	See Rema	1	S	-90	20.04	-5		179	D
10/6/25 09:12	10/3/25	PMN	Promis Neurosciences Inc.	Z4	Health	Drug	Pharmaceutical Preparations	Milbury Max A.	A6	H	Principa	1	P	15	0.4912	30	203	45	D
10/3/25 21:58	10/2/25	ELTP	Elite Pharmaceuticals Inc /Nv/	NJ	Health	Drug	Pharmaceutical Preparations	Plassche Douglas	NJ	O	EVP Oper	1	S	-499	0.6240	-800		3,500	D
10/3/25 21:27	9/2/25	JAZZ	Jazz Pharmaceuticals Plc	L2	Health	Drug	Pharmaceutical Preparations	Cozadd Bruce C	L2	D		3	S.m	-1,638	131.08	-13		436	D
10/3/25 20:24	10/2/25	CVKD	Cadrenal Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pham Quang X	FL	DOT	CEO,CB	4	S.m	-227	14.04	-16		413	D
10/3/25 19:18	10/3/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Heyman Richard A.	CA	D		1	M.d	56	1.69	33	14	262	D
10/3/25 18:15	10/1/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hamilton James C	CA	O	Chief Me	4	S.m	-1,725	28.75	-60		262	D
10/3/25 17:24	10/1/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Belanoff Joseph K	CA	DO	CEO	4	S	-9,011	74.71	-121		2,901	I
10/3/25 17:17	10/1/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Lyon Joseph Douglas	CA	O	See Rema	8	M.dm	1,738	43.66	40		10	D
10/3/25 17:17	10/1/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Lyon Joseph Douglas	CA	O	See Rema	8	S.dm	-1,738	43.66	-40		10	D
10/3/25 17:15	10/1/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Maduck Sean	CA	O	See Rema	8	M.dm	6,297	39.46	160		118	D
10/3/25 17:15	10/1/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Maduck Sean	CA	O	See Rema	8	S.dm	-6,297	39.46	-160		118	D
10/3/25 17:14	10/2/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Poulton Jeffrey V.	MA	O	EVP,CFO	2	S	-2,758	452.50	-6		54	D
10/3/25 17:14	10/2/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Greenstreet Yvonne	MA	DO	CEO	2	S	-7,197	452.58	-16		66	D
10/3/25 17:14	10/2/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Tanguler Tolga	MA	O	EVP,Chie	3	S	-2,826	450.28	-6		29	D
10/3/25 17:13	10/2/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Fitzgerald Kevin Joseph	MA	O	CSO,EVP,	2	S	-1,736	452.49	-4		26	D
10/3/25 17:12	10/2/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Garg Pushkal	MA	O	EVP Chie	2	S.m	-3,992	453.10	-9		21	D
10/3/25 17:02	10/1/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Watanabe Todd	CA	DO	See Rema	3	S.m	-1,228	18.41	-67		1,135	D
10/3/25 17:01	10/1/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Welgus Howard G.	CA	D		6	M.d	505	8.48	60	146	100	D
10/3/25 17:01	10/1/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Welgus Howard G.	CA	D		6	S.d	-505	8.48	-60		100	D
10/3/25 16:56	9/3/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Abate Kristin	MA	O	Chief Ac	4	S	-3	5.45	-1		10	D
10/3/25 16:45	10/1/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Kozarich John W	FL	D		3	S	-221	157.86	-1		46	D
10/3/25 16:41	9/2/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pizzuti Dana	CA	O	Chief Me	7	M.d	2,147	24.83	86	885	96	D
10/3/25 16:41	9/2/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pizzuti Dana	CA	O	Chief Me	7	S.d	-2,147	24.83	-86		96	D
10/3/25 16:30	9/2/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Young Jonathan	CA	O	COO	7	M.d	2,587	34.22	76	42	257	D
10/3/25 16:30	9/2/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Young Jonathan	CA	O	COO	7	S.d	-2,587	34.22	-76		257	D
10/3/25 16:28	10/1/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Balcom Alexandra	MA	O	CFO	6	M.dm	6,494	48.04	135		62	D
10/3/25 16:28	10/1/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Balcom Alexandra	MA	O	CFO	6	S.dm	-6,494	48.04	-135		62	D
10/3/25 16:25	10/1/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ticho Barry	MA	O	Chief Me	5	S.d	-345	12.24	-28		27	D
10/3/25 16:20	10/1/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Chen Yajing	MA	O	CFO	5	M.d	206	25.23	8	90	17	D
10/3/25 16:20	10/2/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Chen Yajing	MA	O	CFO	5	S.d	-206	25.23	-8		17	D
10/3/25 16:07	10/2/25	VRTX	Vertex Pharmaceuticals Inc / Ma	MA	Health	Drug	Pharmaceutical Preparations	Biller Jonathan	MA	O	EVP,GC	1	S	-281	404.21	-1		16	D
10/3/25 13:18	10/2/25	SNGX	Soligenix, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Schaber Christopher J	NJ	DO	CB,CEO,P	1	P	20	1.32	15	999%	16	D
10/2/25 19:36	10/1/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Wender Joseph H	CA	D		4	S.dm	-4,325	56.25	-77		137	I
10/2/25 19:24	10/1/25	TERN	Terns Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kuriakose Emil	CA	O	Chief Me	1	S	-7	7.85	-1		52	D
10/2/25 17:04	10/1/25	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	Petersen Floyd F.	CA	D		3	S	-40	26.34	-2		77	D
10/2/25 16:51	10/1/25	MAIA	Maia Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Smith Stan	IL	D		1	P.d	25	1.30	19	1	1,324	I
10/2/25 16:47	9/30/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Baker Bros. Advisors LP	NY	H	Former 1	3	S.m	-62,978	70.28	-896		2,373	I
10/2/25 16:44	9/30/25	SAVA	Cassava Sciences Inc	DE	Health	Drug	Pharmaceutical Preparations	Cook Robert Christopher	TX	O	COO,Lega	1	P	40	2.91	14		14	D
10/2/25 16:30	8/21/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	12	M.d	32,487	246.11	132		37	D
10/2/25 16:30	8/21/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	12	S.d	-32,487	246.11	-132		37	D
10/2/25 16:17	9/30/25	ANNX	Annexon, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Carson William H.	CA	D		3	P	31	2.52	12	42	42	D
10/2/25 16:15	9/30/25	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Klee Justin B.	MA	DO	Co-CEO	1	S	-431	14.38	-30		3,325	D
10/2/25 16:15	9/30/25	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mazzariello Gina	MA	O	GC	2	S.m	-375	9.65	-39		157	D
10/2/25 16:15	9/30/25	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Frates James M	MA	O	CFO	1	S	-155	14.65	-11		307	D
10/2/25 16:15	9/30/25	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cohen Joshua B	MA	DO	Co-CEO	1	S	-429	14.35	-30		3,325	D
10/2/25 16:15	9/30/25	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bedrosian Camille L	MA	O	Chief Me	1	S	-176	14.58	-12		182	D
10/2/25 16:10	10/1/25	FBRX	Forte Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Riley Antony A	TX	O	CFO	1	M.d	0	0.00	0	1	32	D
10/2/25 16:09	10/1/25	FBRX	Forte Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Wagner Paul A.	TX	DO	See Rema	1	M.d	0	0.00	1	2	82	D
10/2/25 16:05	9/30/25	ALLR	Allarity Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Graff Jeremy R.	FL	O	See Rema	1	M.d	0	0.00	39		25	D
10/2/25 16:05	9/30/25	HRMY	Harmony Biosciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kapadia Sandip	PA	O	CFO	2	M.d	787	11.83	67		21	D
10/2/25 16:02	9/30/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dunlop A. Sinclair	MA	D		2	S	-1,416	22.77	-62		223	I
10/2/25 15:04	9/30/25	MNPR	Monopar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	Cittadine Andrew	IL	O	COO	1	M.d	0	0.00	4	10	48	D
10/2/25 15:04	9/30/25	MNPR	Monopar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	Robinson Chandler	IL	DO	CEO	2	M.d	672	26.33	26	3	896	D
10/2/25 09:02	10/1/25	IMRX	Immuneering Corp	DE	Health	Drug	Pharmaceutical Preparations	Morales Mallory	MA	O	Chief Ac	1	P	2	6.39	0	1	28	D
10/2/25 08:57	10/1/25	IMRX	Immuneering Corp	DE	Health	Drug	Pharmaceutical Preparations	Neufeld Leah R	MA	O	CHIEF PE	1	P	5	6.38	1	4	23	D
10/2/25 08:52	10/1/25	IMRX	Immuneering Corp	DE	Health	Drug	Pharmaceutical Preparations	Bookman Michael	MA	O	GC,SECRE	1	P	7	6.83	1	26	5	D
10/1/25 20:14	8/25/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Noci Darlene	MA	O	Chief De	6	M.d	1,286	53.60	24	100	48	D
10/1/25 20:14	8/25/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Noci Darlene	MA	O	Chief De	6	S.d	-1,286	53.60	-24		48	D
10/1/25 19:17	10/1/25	XENE	Xenon Pharmaceuticals Inc.	A1	Health	Drug	Pharmaceutical Preparations	Mortimer Ian	A1	DO	P,CEO,IN	2	M.d	1,196	23.93	50		46	D
10/1/25 19:17	10/1/25	XENE	Xenon Pharmaceuticals Inc.	A1	Health	Drug	Pharmaceutical Preparations	Mortimer Ian	A1	DO	P,CEO,IN	2	S.d	-1,196	23.93	-50		46	D
10/1/25 19:00	9/30/25	BTAI	Bioxcel Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mack David J.	CT	D		3	M.d	0	0.00	5	38	19	D
10/1/25 17:22	8/11/25	MLTX	Moonlake Immunotherapeutics	E9	Health	Drug	Pharmaceutical Preparations	Chen Bihua	MA	H	Former 1	2	M.dm	46,868	4.39	10,672	116	19,873	I
10/1/25 17:16	9/29/25	PGEN	Precigen, Inc.	VA	Health	Drug	Pharmaceutical Preparations	Kindler Jeffrey B	MD	D		1	S.m	-604	3.47	-174		346	D
10/1/25 16:57	9/29/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Meisner Lara	MA	O	GC	4	M.d	1,079	10.87	99		0	D
10/1/25 16:57	9/29/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Meisner Lara	MA	O	GC	4	S.d	-1,079	10.87	-99	-100	0	D
10/1/25 16:55	9/30/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Geary Richard S	CA	O	EVP,Chie	4	M.d	7,823	57.61	136		89	D
10/1/25 16:55	9/30/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Geary Richard S	CA	O	EVP,Chie	4	S.d	-7,823	57.61	-136		89	D
10/1/25 16:47	8/6/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Levin Arthur A	MA	D		3	M.d	7,520	34.78	216		195	D
10/1/25 16:47	8/6/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Levin Arthur A	MA	D		3	S.d	-7,520	34.78	-216		195	D
10/1/25 16:46	9/29/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hohl Benjamin	CO	O	CFO	6	M.d	224	11.49	20	557	23	D
10/1/25 16:46	9/29/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hohl Benjamin	CO	O	CFO	6	S.d	-224	11.49	-20		23	D
10/1/25 16:44	9/29/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Tessari Eben	X0	O	COO	14	M.dm	16,217	24.28	668		50	D
10/1/25 16:44	9/29/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Tessari Eben	X0	O	COO	14	S.dm	-16,217	24.28	-668		50	D
10/1/25 16:43	9/30/25	ZTS	Zoetis Inc.		Health	Drug	Pharmaceutical Preparations	Fuller Julie	NJ	O	EVP	1	M.d	0	0.00	1		1	D
10/1/25 16:30	9/29/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	O'Malley Brendan M.	OH	O	SVP,GC	2	S	-54	5.40	-10		360	D
10/1/25 16:30	9/29/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Seshadri Vishwas	OH	DO	CEO	1	S.m	-235	5.31	-44		1,190	D
10/1/25 16:30	7/22/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Vazzano Joseph Walter	OH	O	CFO	3	S	-169	6.62	-26		478	D
10/1/25 16:26	9/2/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Blum Robert I	CA	DO	P,CEO	6	S	-1,333	44.43	-30		397	D
10/1/25 16:24	10/1/25	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chole Timothy	MI	O	SVP,CCO	1	S	-3	1.19	-3		125	D
10/1/25 16:23	10/1/25	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Neri Jesse	MI	O	SVP,CFO	1	S	-1	1.19	-1		126	D
10/1/25 16:22	10/1/25	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Strobeck Mark	MI	DO	P,CEO	1	S	-8	1.19	-7		331	D
10/1/25 16:10	9/9/25	PAHC	Phibro Animal Health Corp	DE	Health	Drug	Pharmaceutical Preparations	Bendheim Jack	NJ	DOT	P,CEO	3	S.dm	-1,974	40.46	-49		78	I
10/1/25 16:00	9/30/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Loumeau Eric J	CA	O	GC	2	M.d	309	23.34	13		9	D
10/1/25 16:00	9/30/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Loumeau Eric J	CA	O	GC	2	S.d	-309	23.34	-13		9	D
10/1/25 13:07	9/30/25	PEPG	Pepgen Inc.	DE	Health	Drug	Pharmaceutical Preparations	Oxford Science Enterprises Plc	X0	H	Former 1	1	P	640	3.20	200	4	4,955	D
9/30/25 18:59	9/29/25	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Azoy Alexander	CA	O	Chief Ac	2	S	-56	12.60	-4		30	D
9/30/25 17:56	9/26/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jones Cecilia	MA	O	CFO	2	M.d	134	12.07	11	49	34	D
9/30/25 17:56	9/26/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jones Cecilia	MA	O	CFO	2	S.d	-134	12.07	-11		34	D
9/30/25 17:53	9/26/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lyssikatos Joseph P	CO	O	CHIEF SC	5	S.m	-774	20.63	-38		953	I
9/30/25 17:51	9/26/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kintz Samuel	CO	DO	P,CEO	6	S.m	-778	20.74	-38		940	I
9/30/25 17:44	9/30/25	PGEN	Precigen, Inc.	VA	Health	Drug	Pharmaceutical Preparations	Kirk Randal J	VA	DT		3	S.dm	-24,824	1.03	-24,195		128,722	I
9/30/25 16:59	9/26/25	MBX	Mbx Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Heron Patrick J	CA	DT		1	P	12,000	18.00	667	15	5,219	I
9/30/25 16:42	9/26/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Struthers Richard Scott	CA	DO	P,CEO	1	S	-180	45.00	-4	0	1,298	I
9/30/25 16:41	9/26/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fust Matthew K	CA	D		2	M.d	735	28.27	26		23	D
9/30/25 16:41	9/26/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Fust Matthew K	CA	D		2	S.d	-735	28.27	-26		23	D
9/30/25 16:35	9/4/25	PEPG	Pepgen Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ra Capital Management, L.P.	MA	DT		2	P	60,000	5.69	10,551	63	27,388	I
9/30/25 16:09	8/26/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cloonan Michael	MA	DO	P,CEO	6	M.dm	2,379	15.86	150	38	547	D
9/30/25 16:09	8/26/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cloonan Michael	MA	DO	P,CEO	6	S.dm	-2,379	15.86	-150		547	D
9/30/25 16:07	9/26/25	PGEN	Precigen, Inc.	VA	Health	Drug	Pharmaceutical Preparations	Shah Rutul R	MD	O	COO	1	P	7	3.40	2	0	406	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

TC

Stat

Stk

Ins

Fil

+d

+w

+m

+q

+h

+y

avg

Filing Date

T Date

Ticker

Issuer

Inc

Sector

Ind

Industry

Owner

oSt

Rel

Title

#f

T

TVal

Price

L

Qty

oc

Own

H

r2y

r1y

r6m

r3m

r6w

r3w

r7d

r3d

f1d

f1w

f1m

f3m

f6m

f1y