Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	#o	#f	T	TVal	Price	Qty	oc	Own	H
4/25/25 20:20	4/25/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	6	13	S.dm	-4,367	15.74	-277		1,041	D
4/24/25 16:40	4/23/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	10	S	-171	4.71	-36		1,535	D
4/24/25 16:28	4/22/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	12	S.dm	-142,450	35.12	-4,056		28,481	I
4/24/25 16:06	4/22/25	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	8	S.m	-578	11.00	-53		2,317	D
4/23/25 20:00	4/21/25	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	3	S.d	-348	34.81	-10		82	D
4/23/25 18:00	4/21/25	TBPH	Theravance Biopharma, Inc.	E9	Health	Drug	Pharmaceutical Preparations	1	1	S	-36	9.00	-4		370	D
4/23/25 17:09	4/21/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	12	S.d	-1,341	20.08	-67		2,346	I
4/23/25 16:44	4/21/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	4	8	S.dm	-3,002	21.70	-138		141	D
4/23/25 16:30	4/22/25	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	4	5	S.d	-3,666	55.10	-67		700	D
4/23/25 16:15	4/21/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	6	12	S.d	-591	13.71	-43		4,258	D
4/22/25 21:00	4/21/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	2	5	S.dm	-17,212	10.67	-1,613		1,291	D
4/22/25 16:33	4/22/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	6	27	S.d	-9,313	42.75	-218		746	D
4/22/25 16:30	4/21/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	6	16	S.d	-38,944	328.14	-119		78	D
4/21/25 16:04	4/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	7	S	-29	1.50	-19		2,424	D
4/17/25 17:41	4/15/25	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	4	9	S.dm	-3,056	4.13	-741		487	D
4/17/25 16:55	4/15/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	7	S.dm	-9,087	73.88	-123		1,943	D
4/17/25 16:53	4/16/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	9	13	S.d	-2,340	31.54	-74		687	D
4/17/25 16:05	4/15/25	ETNB	89Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-91	5.95	-15		343	D
4/16/25 18:00	4/15/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	22	S.d	-19,462	49.82	-391		1,389	D
4/16/25 17:12	4/14/25	BGNE	Beigene, Ltd.		Health	Drug	Pharmaceutical Preparations	6	17	S.dm	-325,349	256.11	-1,270		73,887	D
4/16/25 17:00	4/15/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S	-174	10.21	-17		469	D
4/16/25 16:17	4/15/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	7	18	S.dm	-44,893	79.71	-563		1,571	I
4/15/25 20:39	4/14/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	S.d	-1,361	14.60	-93		1,194	D
4/15/25 17:30	3/31/25	ASMB	Assembly Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	S.d	-15	9.85	-1		49	D
4/15/25 16:31	4/14/25	SDGR	Schrodinger, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	8	S.d	-759	24.76	-31		131	D
4/14/25 18:23	4/11/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	8	15	S.dm	-4,119	22.31	-185		1,018	D
4/14/25 17:58	4/10/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	5	16	S.dm	-38,824	92.69	-419		3,140	D
4/14/25 16:17	3/19/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	3	7	S.d	-642	61.45	-10		245	D
4/14/25 16:13	4/10/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	5	5	S	-543	13.10	-41		881	D
4/11/25 21:45	4/9/25	OSTX	Os Therapies Inc	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.m	-366	2.29	-160		2,770	I
4/11/25 18:20	4/9/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.dm	-7,603	15.41	-494		4,098	D
4/10/25 17:17	4/8/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	23	S.dm	-8,646	55.51	-156		388	D
4/10/25 16:02	4/10/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	8	S.d	-1,217	33.48	-36		379	D
4/8/25 21:36	3/26/25	NTHI	Neonc Technologies Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	5	S.ad	-3,824	24.85	-154		15,023	I
4/8/25 19:40	4/8/25	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	3	7	S.d	-243	17.13	-14		99	D
4/8/25 19:24	4/4/25	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	7	S.d	-848	5.22	-162		2,431	D
4/8/25 17:32	4/4/25	OKUR	Onkure Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S.m	-12	2.94	-4		17	D
4/8/25 17:01	4/7/25	PHAT	Phathom Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-17	4.55	-4		92	D
4/8/25 16:45	4/7/25	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.dm	-1,931	12.07	-160		218	D
4/7/25 18:43	4/3/25	ALDX	Aldeyra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-4,828	1.42	-3,400		5,876	I
4/7/25 17:18	4/3/25	IBO	Impact Biomedical Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	1	S	-174	0.4950	-352	-100	0	I
4/7/25 16:48	4/4/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	7	16	S.dm	-9,495	34.12	-278		746	D
4/4/25 19:27	4/2/25	MNPR	Monopar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-1,167	35.00	-33		822	D
4/4/25 17:35	4/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	6	6	S.m	-85	7.73	-11		838	D
4/4/25 16:18	4/4/25	BFRG	Bullfrog Ai Holdings, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	2	S.m	-74	1.48	-50		2,348	D
4/3/25 19:27	4/2/25	CKPT	Checkpoint Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.m	-447	3.69	-121		5,234	D
4/3/25 17:32	2/3/25	JAZZ	Jazz Pharmaceuticals Plc	L2	Health	Drug	Pharmaceutical Preparations	4	8	S.dm	-4,134	140.10	-30		607	D
4/3/25 17:00	4/2/25	VERV	Verve Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	6	S.d	-100	4.15	-24		1,099	D
4/3/25 16:56	4/1/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	9	S.d	-3,259	30.67	-106		715	D
4/3/25 16:30	4/2/25	SYBX	Synlogic, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S	-3	1.32	-2		13	D
4/3/25 16:30	4/1/25	BPMC	Blueprint Medicines Corp	DE	Health	Drug	Pharmaceutical Preparations	11	16	S.dm	-7,751	89.05	-87		805	D
4/3/25 16:27	4/2/25	INZY	Inozyme Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.d	-8	0.8900	-9		41	D
4/3/25 16:21	4/2/25	VTYX	Ventyx Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-2	1.07	-2	0	467	D
4/3/25 16:21	4/1/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	14	S.dm	-2,518	14.00	-180		1,997	D
4/3/25 16:17	4/2/25	UBX	Unity Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	7	S.d	-145	1.04	-139		319	D
4/3/25 16:15	4/1/25	HRMY	Harmony Biosciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.dm	-1,006	35.43	-28	-100	0	D
4/2/25 18:48	4/1/25	TERN	Terns Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-2	2.49	-1		53	D
4/2/25 18:45	4/1/25	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	2	3	S.d	-159	27.69	-6		170	D
4/2/25 18:06	4/1/25	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-12	1.08	-11		201	D
4/2/25 17:22	3/31/25	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	12	S	-404	3.43	-118		7,410	D
4/2/25 17:00	3/31/25	ABBV	Abbvie Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	8	S.dm	-57,730	207.00	-279		533	D
4/2/25 16:12	4/1/25	AMRX	Amneal Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	6	8	S.m	-47,284	8.39	-5,635		51,582	D
3/31/25 19:17	3/31/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-141	4.86	-29		1,420	D
3/28/25 18:59	3/27/25	EOLS	Evolus, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	6	S	-2,164	13.20	-164		1,179	D
3/26/25 19:08	2/18/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	13	S.dm	-41,520	54.28	-765		829	D
3/26/25 19:01	3/24/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	4	10	S.d	-132	6.00	-22		1,109	D
3/26/25 17:04	3/24/25	DVAX	Dynavax Technologies Corp	DE	Health	Drug	Pharmaceutical Preparations	1	3	S.d	-802	14.12	-57		22	D
3/26/25 16:30	3/25/25	TRVI	Trevi Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S.d	-601	6.74	-89		512	D
3/26/25 16:05	3/18/25	HROW	Harrow, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	3	S	-439	29.23	-15	0	3,955	I
3/25/25 16:10	3/21/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	6	17	S.dm	-25,976	277.06	-94		242	D
3/25/25 16:10	3/21/25	MRUS	Merus N.V.	P7	Health	Drug	Pharmaceutical Preparations	1	1	S.d	-194	48.50	-4		11	D
3/25/25 16:01	3/21/25	GYRE	Gyre Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	21	S.m	-896	11.45	-78		2,899	I
3/24/25 21:00	3/21/25	ATAI	Atai Life Sciences N.V.	P7	Health	Drug	Pharmaceutical Preparations	5	5	S	-246	1.35	-182		523	D
3/24/25 17:06	3/20/25	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	3	10	S.dm	-4,886	29.08	-168		426	D
3/24/25 16:39	3/20/25	VSTM	Verastem, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	5	S.m	-13	6.43	-2	0	562	D
3/24/25 16:33	3/21/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	7	S	-361	7.94	-45		411	D
3/21/25 21:00	3/20/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	2	2	S.d	-1,720	9.58	-180		354	D
3/21/25 18:34	3/19/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	5	S.d	-1,317	34.85	-38		1,489	D
3/21/25 17:31	3/20/25	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	1	1	S	-217	5.43	-40		1,354	D
3/20/25 19:38	3/19/25	BMRN	Biomarin Pharmaceutical Inc	DE	Health	Drug	Pharmaceutical Preparations	2	3	S	-686	70.91	-10		105	D
3/20/25 18:15	3/18/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S.dm	-261	8.49	-31		232	D
3/20/25 17:21	3/20/25	CLYM	Climb Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.d	-2	1.31	-1		15	D
3/20/25 16:34	3/18/25	CTMX	Cytomx Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	5	S	-48	0.5990	-80		1,794	D
3/19/25 18:47	3/18/25	CLNN	Clene Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.m	-12	4.42	-3	0	711	D
3/19/25 18:11	3/17/25	SLRN	Acelyrin, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-69	2.74	-25		915	D
3/19/25 17:40	3/18/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	12	S.d	-7,910	45.53	-174		382	D
3/19/25 16:49	3/17/25	TSVT	2Seventy Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	S	-80,103	4.93	-16,248		1,820	D
3/19/25 16:32	3/17/25	TRDA	Entrada Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-19	10.67	-2		110	D
3/19/25 15:31	3/18/25	NIKA	Nika Pharmaceuticals, Inc	CO	Health	Drug	Pharmaceutical Preparations	1	1	S	-500	0.2500	-2,000	0	455,590	D
3/19/25 14:48	3/18/25	OPTN	Optinose, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	5	S	-55	5.31	-10		226	D
3/19/25 08:06	3/18/25	ARVN	Arvinas, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	5	S	-840	15.42	-54		1,543	D
3/18/25 19:10	3/14/25	IGMS	Igm Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	S	-26	1.23	-21		622	D
3/18/25 18:45	3/17/25	VRCA	Verrica Pharmaceuticals Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.d	-3	0.6501	-4		176	D
3/18/25 18:35	3/14/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.d	-1,021	12.90	-79	-100	0	D
3/18/25 12:27	3/17/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	10	12	S	-374	27.61	-14	0	3,952	D
3/17/25 17:14	3/13/25	NGNE	Neurogene Inc.		Health	Drug	Pharmaceutical Preparations	1	1	S	-76	16.94	-5		72	D
3/17/25 16:09	3/13/25	VRTX	Vertex Pharmaceuticals Inc / Ma	MA	Health	Drug	Pharmaceutical Preparations	6	21	S	-18,923	483.40	-39		217	D
3/14/25 16:30	3/12/25	RPTX	Repare Therapeutics Inc.	Z4	Health	Drug	Pharmaceutical Preparations	4	4	S	-42	1.14	-37		595	D
3/14/25 16:25	3/12/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	9	13	S.dm	-25,179	342.89	-73		1,588	D
3/13/25 20:15	3/12/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	1	1	S	-662	8.35	-79		2,609	D
3/13/25 20:00	3/12/25	SRPT	Sarepta Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.d	-248	99.64	-2		28	D
3/13/25 16:17	3/3/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	3	10	S.ed	-789,546	896.19	-881		96,902	D
3/13/25 16:13	3/13/25	DYN	Dyne Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	9	S	-200	12.40	-16		692	D
3/12/25 18:13	3/12/25	EBS	Emergent Biosolutions Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-261	5.81	-45		146	D
3/12/25 16:01	3/10/25	PBH	Prestige Consumer Healthcare Inc.		Health	Drug	Pharmaceutical Preparations	2	3	S.d	-1,648	86.47	-19		37	D
3/11/25 20:17	3/7/25	YMAB	Y-Mabs Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-77	5.22	-15		467	D
3/11/25 19:53	3/11/25	DERM	Journey Medical Corp	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.m	-818	5.06	-162		2,139	D
3/11/25 16:33	3/7/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	6	S.dm	-1,564	28.94	-54		401	D
3/11/25 16:20	3/10/25	ZTS	Zoetis Inc.		Health	Drug	Pharmaceutical Preparations	3	4	S.d	-372	165.82	-2		123	D
3/10/25 20:07	3/10/25	PRGO	Perrigo Co Plc	L2	Health	Drug	Pharmaceutical Preparations	1	1	S.d	-214	27.44	-8		34	D
3/10/25 18:43	3/7/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	S.d	-229	10.52	-22		485	D
3/10/25 12:53	3/6/25	RARE	Ultragenyx Pharmaceutical Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	9	S.dm	-6,810	42.15	-162		3,565	D
3/7/25 18:55	3/6/25	ABT	Abbott Laboratories	IL	Health	Drug	Pharmaceutical Preparations	9	10	S.dm	-77,945	130.58	-597		1,101	D
3/7/25 17:25	3/7/25	AUPH	Aurinia Pharmaceuticals Inc.		Health	Drug	Pharmaceutical Preparations	5	6	S.dm	-5,947	7.97	-746		3,718	D
3/7/25 17:00	3/5/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S.dm	-7,038	22.10	-318		257	D
3/7/25 16:30	3/6/25	CRBP	Corbus Pharmaceuticals Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-130	7.98	-16		282	D
3/7/25 16:05	3/5/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	7	12	S.dm	-11,235	16.12	-697		842	D
3/6/25 21:30	3/4/25	INVA	Innoviva, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.m	-28,395	17.55	-1,618		5,659	I
3/6/25 21:08	3/4/25	ORGO	Organogenesis Holdings Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-128	5.10	-25		167	D
3/6/25 20:30	3/4/25	APLT	Applied Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	S	-95	0.5835	-162		1,578	D
3/6/25 18:55	3/4/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.d	-575	115.03	-5		26	D
3/6/25 16:10	3/4/25	SNDX	Syndax Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	3	4	S.d	-454	15.38	-29		476	D
3/6/25 13:57	3/4/25	PFE	Pfizer Inc	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.d	-65	25.93	-3		12	D
3/5/25 17:32	3/4/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	4	6	S.dm	-1,034	10.56	-98		1,141	D
3/5/25 16:49	3/4/25	MURA	Mural Oncology Plc	L2	Health	Drug	Pharmaceutical Preparations	3	3	S.dm	-75	3.71	-20		434	D
3/4/25 18:09	3/3/25	AADI	Aadi Bioscience, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S.d	-25	2.35	-11		260	D
3/4/25 17:05	3/3/25	AKBA	Akebia Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	6	S.d	-687	2.06	-334		4,463	D
3/4/25 16:59	2/28/25	CARA	Cara Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S	-5	4.74	-1		21	D
3/3/25 17:29	3/3/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	5	S.d	-392	18.41	-21		128	D
2/28/25 18:54	11/15/24	SKYE	Skye Bioscience, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	1	S.am	-216	4.99	-43		168	D
2/28/25 17:19	2/28/25	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	2	5	S.dm	-15,329	33.52	-457		66	D
2/28/25 16:48	2/26/25	CYCC	Cyclacel Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.d	-5,508	0.0283	-194,629	-100	0	D
2/28/25 16:15	2/26/25	OVID	Ovid Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-5	0.5600	-9		141	D
2/27/25 16:05	2/21/25	VERA	Vera Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.m	-547	27.78	-20		427	D
2/26/25 20:24	2/26/25	PEPG	Pepgen Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-5	1.68	-3		3	D
2/26/25 18:42	2/25/25	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	3	3	S.d	-3,227	158.04	-20		108	D
2/26/25 18:27	2/24/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	5	5	S.m	-338	7.22	-47		4,473	D
2/24/25 20:20	2/21/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S.dm	-542	39.64	-14		21	D
2/21/25 19:27	2/19/25	FOLD	Amicus Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.d	-4	10.00	0	0	1,151	D
2/21/25 18:10	2/18/25	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S.d	-252	11.96	-21		2,029	D
2/21/25 18:07	2/19/25	NKTR	Nektar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-46	1.01	-45		1,728	D
2/21/25 16:25	2/19/25	ALXO	Alx Oncology Holdings Inc	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-5	1.15	-4	0	837	D
2/20/25 16:54	2/18/25	ANNX	Annexon, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	9	S	-126	2.95	-43		716	D
2/20/25 16:01	2/19/25	MRK	Merck & Co., Inc.	NJ	Health	Drug	Pharmaceutical Preparations	3	3	S	-1,436	85.19	-17		62	D
2/19/25 20:11	2/18/25	MCRB	Seres Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	5	S.d	-23	0.8104	-29		556	D
2/19/25 16:23	2/15/25	MGNX	Macrogenics Inc	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.d	-1	2.56	0		10	D
2/14/25 21:20	2/13/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.dm	-1,952	130.10	-15		43	D
2/14/25 17:57	2/13/25	ZVRA	Zevra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	S.m	-920	7.91	-116		289	D
2/14/25 17:50	2/13/25	CMRX	Chimerix Inc	DE	Health	Drug	Pharmaceutical Preparations	5	8	S	-91	4.39	-21		1,308	D
2/12/25 21:00	2/10/25	IRWD	Ironwood Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	5	5	S	-428	1.76	-243		2,586	D
2/12/25 20:45	2/10/25	LFVN	Lifevantage Corp		Health	Drug	Pharmaceutical Preparations	3	3	S	-365	19.92	-18		275	D
2/7/25 16:43	2/5/25	TYRA	Tyra Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S	-153	14.94	-10	0	4,150	I
2/6/25 20:27	2/4/25	RIGL	Rigel Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	4	4	S.m	-424	21.39	-20		387	D
2/6/25 20:21	2/4/25	TNGX	Tango Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	S.m	-143	3.07	-47		1,997	D
2/5/25 21:04	2/5/25	SPRO	Spero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	S	-235	0.7800	-302		3,893	D
2/5/25 18:33	2/3/25	ZNTL	Zentalis Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	3	3	S.d	-52	1.71	-30		1,773	D
2/5/25 16:02	2/4/25	ABUS	Arbutus Biopharma Corp	A1	Health	Drug	Pharmaceutical Preparations	4	4	S	-252	3.28	-77		1,833	D
2/4/25 11:53	1/31/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	2	2	S.d	-133	11.14	-12		181	D
1/31/25 18:20	1/31/25	MRVI	Maravai Lifesciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-126	5.03	-25		168	D
1/30/25 18:39	1/28/25	EVOK	Evoke Pharma Inc	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	0	4.39	0	0	148	I
1/27/25 20:28	1/23/25	XENE	Xenon Pharmaceuticals Inc.	A1	Health	Drug	Pharmaceutical Preparations	1	1	S.dm	-2,214	40.25	-55		46	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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