Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	#o	#f	T	TVal	Price	Qty	oc	Own	H
9/3/25 06:04	8/28/25	SPRO	Spero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-16	1.97	-8		1,443	D
9/2/25 20:30	9/2/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	10	13	S.d	-22,611	44.53	-508		1,627	D
9/2/25 19:46	8/28/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	10	18	S.dm	-22,672	26.58	-853		10,628	I
9/2/25 19:11	9/2/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	S.dm	-19,782	115.57	-171		137	D
9/2/25 16:41	9/2/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	4	13	S.d	-1,946	39.78	-49		592	D
9/2/25 16:39	8/21/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	5	10	S.d	-25,807	304.76	-85		74	D
9/2/25 16:10	8/29/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	7	8	S.dm	-27,109	443.92	-61		206	D
8/29/25 20:35	8/27/25	CVKD	Cadrenal Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S.m	-98	13.99	-7		445	D
8/29/25 18:46	8/22/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	5	9	S.dm	-3,385	6.88	-492		1,354	D
8/29/25 17:30	8/27/25	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	3	4	S.dm	-4,813	55.41	-87		624	D
8/29/25 17:21	8/28/25	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	3	3	S.d	-1,430	7.44	-192		1,178	D
8/29/25 17:03	8/27/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	15	S.dm	-2,284	21.01	-109		2,244	D
8/29/25 16:19	8/27/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	6	S.dm	-9,895	24.79	-399		2,096	I
8/29/25 16:09	8/27/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	10	S.d	-2,034	35.29	-58		287	D
8/29/25 16:05	8/25/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	11	S.dm	-9,525	42.92	-222		2,296	D
8/29/25 16:02	8/27/25	VRTX	Vertex Pharmaceuticals Inc / Ma	MA	Health	Drug	Pharmaceutical Preparations	1	1	S	-103	386.69	0		5	D
8/28/25 20:39	8/26/25	BYSI	Beyondspring Inc.		Health	Drug	Pharmaceutical Preparations	1	5	S.m	-1,340	2.89	-464		4,488	I
8/28/25 19:32	8/26/25	QTTB	Q32 Bio Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-32	1.80	-18		265	D
8/28/25 19:30	8/26/25	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	7	S.d	-997	6.02	-166		3,217	D
8/28/25 17:40	8/26/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.dm	-2,919	23.28	-125		619	D
8/28/25 17:00	8/27/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	5	S.dm	-8,652	23.52	-368		5,989	D
8/28/25 16:55	8/26/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	7	S.d	-1,711	14.41	-119		538	D
8/28/25 16:25	8/27/25	AMRX	Amneal Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	6	10	S.dm	-11,577	9.19	-1,260		2,658	D
8/28/25 16:14	7/24/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	3	3	S	-226,938	804.03	-282	0	95,769	D
8/28/25 16:05	8/27/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	2	2	S	-20	15.62	-1		181	D
8/27/25 18:44	8/25/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	4	4	S	-355	12.04	-29		4,221	D
8/27/25 17:16	8/18/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	1	10	S.dm	-618	6.20	-100	-100	0	D
8/27/25 17:08	8/25/25	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	3	4	S.dm	-6,703	21.84	-307		128	D
8/27/25 16:30	8/7/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	12	S.dm	-12,468	79.34	-157		422	D
8/26/25 21:40	8/22/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	5	7	S.d	-2,835	9.64	-294		6,193	D
8/26/25 20:00	8/25/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	13	S.d	-1,545	14.82	-104		674	D
8/26/25 18:56	8/22/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	6	18	S.dm	-11,416	70.16	-163		3,071	D
8/26/25 18:26	8/22/25	EOLS	Evolus, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S.m	-1,326	9.92	-134		455	D
8/26/25 18:19	8/22/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	13	17	S.dm	-35,690	88.01	-406		1,905	D
8/26/25 18:01	8/22/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	12	S.dm	-8,006	58.91	-136		1,434	I
8/26/25 17:23	8/22/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	6	7	S.d	-1,705	43.10	-40		519	D
8/26/25 17:17	7/8/25	ELTP	Elite Pharmaceuticals Inc /Nv/	NJ	Health	Drug	Pharmaceutical Preparations	2	2	S.d	-378	0.5399	-700		6,600	D
8/26/25 16:30	8/22/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S.d	-4,244	31.68	-134		166	D
8/26/25 16:15	8/22/25	TNGX	Tango Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S	-9,828	7.01	-1,402		15,759	D
8/25/25 20:59	8/21/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	12	S.dm	-9,978	83.72	-119		151	D
8/25/25 19:12	8/22/25	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	3	3	S.d	-28,654	177.12	-162		503	D
8/22/25 21:00	6/18/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	2	5	S.dm	-25,009	11.42	-2,191		53,438	D
8/22/25 20:49	8/21/25	DVAX	Dynavax Technologies Corp	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.m	-22,352	10.82	-2,065		15,726	D
8/22/25 19:07	8/21/25	SKYE	Skye Bioscience, Inc.	NV	Health	Drug	Pharmaceutical Preparations	2	2	S.m	-1,601	3.46	-463		19,364	I
8/22/25 16:58	8/21/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	12	S.dm	-184,917	44.31	-4,173		26,998	D
8/22/25 16:30	8/21/25	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	6	S.dm	-15,774	17.87	-883		32,459	I
8/22/25 16:19	8/21/25	BHC	Bausch Health Companies Inc.	NJ	Health	Drug	Pharmaceutical Preparations	1	1	S	-122	7.66	-16		74	D
8/22/25 16:07	8/21/25	LYEL	Lyell Immunopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	S.m	-134	10.53	-13		124	D
8/21/25 21:32	8/19/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	10	S.dm	-1,254	14.46	-87		1,622	D
8/21/25 21:05	8/19/25	NKTR	Nektar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	3	3	S.d	-79	26.59	-3		109	D
8/21/25 20:44	8/21/25	CLNN	Clene Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-18	5.34	-3	0	705	D
8/21/25 17:44	8/18/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	10	S.dm	-109,462	362.77	-302		2,081	D
8/21/25 17:07	8/4/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	7	19	S.dm	-65,183	99.57	-655		1,397	D
8/20/25 17:14	8/19/25	ETON	Eton Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S.m	-1,178	15.56	-76		817	D
8/20/25 17:00	8/18/25	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	7	S.m	-111	3.02	-37		546	D
8/20/25 16:57	8/18/25	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	4	6	S.d	-2,561	36.63	-70		3,445	D
8/20/25 16:36	8/18/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	6	10	S.dm	-17,160	32.24	-532		287	D
8/20/25 16:13	8/18/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	7	S	-31,219	10.27	-3,039		4,108	D
8/19/25 19:40	8/18/25	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	S.d	-191	6.77	-28		2,145	D
8/19/25 18:00	8/18/25	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-554	25.18	-22		40	D
8/19/25 16:40	8/18/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	6	13	S.dm	-9,583	35.04	-273		754	D
8/19/25 16:15	8/15/25	HRMY	Harmony Biosciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-787	36.50	-22	-100	0	D
8/19/25 16:12	8/15/25	ALXO	Alx Oncology Holdings Inc	DE	Health	Drug	Pharmaceutical Preparations	2	4	S	-3	0.5324	-7		302	D
8/19/25 16:08	8/18/25	MCRB	Seres Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	S.d	-7	16.65	0		28	D
8/18/25 17:14	8/15/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	3	S	-340	13.33	-26		444	D
8/18/25 17:02	8/14/25	SNDX	Syndax Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	3	3	S.dm	-957	14.41	-66		583	D
8/18/25 16:33	8/15/25	EBS	Emergent Biosolutions Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-131	8.75	-15		209	D
8/15/25 18:13	8/15/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	4	9	S.d	-2,563	14.45	-177		709	D
8/15/25 17:59	8/13/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.m	-200	20.00	-10		262	D
8/15/25 16:40	8/1/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	7	21	S.dm	-57,617	282.81	-204	0	68,028	D
8/15/25 16:30	8/14/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	13	S	-1,590	6.25	-255		2,698	D
8/15/25 12:45	8/13/25	NATR	Natures Sunshine Products Inc	UT	Health	Drug	Pharmaceutical Preparations	3	3	S	-32,962	11.49	-2,870		162	D
8/14/25 18:02	8/13/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	S.dm	-1,942	14.45	-134		1,155	D
8/14/25 17:00	8/12/25	ABBV	Abbvie Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S.d	-11,046	198.44	-56		242	D
8/14/25 16:20	8/12/25	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.m	-246	8.21	-30		157	D
8/14/25 16:15	8/13/25	DSGN	Design Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-2,954	5.25	-563		3,655	I
8/13/25 18:37	8/12/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	24	S.dm	-11,755	52.15	-225		1,201	D
8/13/25 18:03	8/11/25	ALDX	Aldeyra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-114	5.15	-22		222	D
8/13/25 16:05	8/11/25	IRWD	Ironwood Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	4	4	S	-11	0.8400	-13		1,101	D
8/13/25 09:58	8/11/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	2	4	S.d	-457	16.44	-28		200	D
8/12/25 20:00	8/11/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	6	S.dm	-5,476	53.56	-102		383	D
8/12/25 16:02	8/8/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.d	-838	22.55	-37		10	D
8/11/25 17:53	8/8/25	ABT	Abbott Laboratories	IL	Health	Drug	Pharmaceutical Preparations	1	1	S	-747	134.55	-6		51	D
8/11/25 16:35	8/11/25	RPRX	Royalty Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	1	1	S.d	-1,214	36.23	-34		195	D
8/11/25 16:09	8/7/25	PCRX	Pacira Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-116	23.67	-5		11	D
8/7/25 16:15	8/5/25	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	3	6	S.m	-149	1.24	-120		8,301	D
8/6/25 20:38	8/6/25	VSTM	Verastem, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	6	S.m	-127	5.19	-24		716	D
8/5/25 20:32	8/1/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	13	16	S.d	-17,148	12.07	-1,421		30,975	D
8/5/25 17:58	8/2/25	BMY	Bristol Myers Squibb Co	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.d	-17	44.23	0		5	D
8/5/25 17:03	8/1/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	2	4	S	-293	121.89	-2		79	D
8/5/25 16:54	8/1/25	JAZZ	Jazz Pharmaceuticals Plc	L2	Health	Drug	Pharmaceutical Preparations	1	2	S	-221	110.42	-2	0	437	D
8/5/25 16:07	8/1/25	AUPH	Aurinia Pharmaceuticals Inc.		Health	Drug	Pharmaceutical Preparations	1	1	S	-210	10.50	-20		133	D
8/5/25 16:04	8/1/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	3	3	S.d	-1,844	16.09	-115		410	D
8/4/25 19:23	7/30/25	CYCC	Cyclacel Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-83	12.36	-7		156	D
8/4/25 19:17	8/1/25	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	1	2	S	-22	22.15	-1		78	D
8/1/25 17:09	8/1/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	S.d	-209	11.71	-18		154	D
8/1/25 16:30	7/30/25	ALZN	Alzamend Neuro, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	3	S.dm	-628	2.58	-243		96	I
7/30/25 16:56	7/29/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-2	4.17	0		37	D
7/29/25 16:52	7/25/25	CALC	Calcimedica, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-4	3.65	-1		13	M
7/25/25 19:06	7/23/25	IGMS	Igm Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	7	S	-41	1.26	-32		616	D
7/23/25 18:09	7/22/25	HOOK	Hookipa Pharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-39	0.9200	-43		136	D
7/23/25 17:00	7/22/25	MURA	Mural Oncology Plc	L2	Health	Drug	Pharmaceutical Preparations	2	3	S	-42	2.45	-17		364	D
7/23/25 16:16	7/21/25	SGMT	Sagimet Biosciences Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-772	9.13	-85		980	D
7/22/25 19:51	7/18/25	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	9	10	S.m	-630	3.44	-183		7,914	D
7/18/25 16:07	7/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	5	S	-51	1.12	-45		2,417	D
7/18/25 16:05	7/17/25	MRUS	Merus N.V.	P7	Health	Drug	Pharmaceutical Preparations	1	3	S.dm	-4,586	55.59	-83	-100	0	D
7/18/25 16:05	7/16/25	PHAT	Phathom Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-14	8.36	-2		54	D
7/17/25 20:51	7/16/25	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	2	3	S	-583	3.97	-147		1,767	D
7/17/25 18:20	7/15/25	ETNB	89Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-115	11.02	-10		324	D
7/16/25 21:06	7/14/25	MNPR	Monopar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	3	3	S.d	-1,700	40.00	-43		922	D
7/16/25 18:01	7/14/25	TBPH	Theravance Biopharma, Inc.	E9	Health	Drug	Pharmaceutical Preparations	1	1	S	-114	11.39	-10		327	D
7/16/25 16:20	7/14/25	ANNX	Annexon, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-8	2.59	-3		357	D
7/11/25 17:27	7/9/25	TRDA	Entrada Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.m	-2,138	7.03	-304		8,567	I
7/8/25 17:55	7/7/25	BRFG	Bullfrog Ai Holdings, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	2	S.m	-77	1.53	-50		2,321	D
7/8/25 16:20	7/3/25	BPMC	Blueprint Medicines Corp	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-285	128.25	-2		117	D
7/8/25 16:00	7/3/25	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S.d	-4	3.38	-1		6	D
7/7/25 17:20	7/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	6	6	S.m	-77	7.27	-11		827	D
7/7/25 16:03	7/3/25	MLTX	Moonlake Immunotherapeutics	E9	Health	Drug	Pharmaceutical Preparations	1	1	S.d	-1,147	48.79	-24	-100	0	D
7/3/25 19:51	7/1/25	PMVP	Pmv Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	S	-152	1.06	-143		1,155	D
7/3/25 19:39	7/1/25	LFVN	Lifevantage Corp		Health	Drug	Pharmaceutical Preparations	1	1	S.d	-37	13.39	-3		133	D
7/3/25 16:15	7/2/25	KZR	Kezar Life Sciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-4	4.28	-1		5	D
7/3/25 15:31	7/3/25	VKTX	Viking Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-985	27.80	-35		2,934	D
7/3/25 14:55	7/1/25	TERN	Terns Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-4	4.27	-1		52	D
7/3/25 13:28	7/1/25	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	S	-18	0.8200	-21		593	D
7/2/25 16:15	6/30/25	PMN	Promis Neurosciences Inc.	Z4	Health	Drug	Pharmaceutical Preparations	1	1	S	0	0.00	-93		2,124	D
7/2/25 16:07	7/1/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	5	S.m	-617	10.29	-60		104	D
7/1/25 21:23	6/27/25	CRVS	Corvus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S.d	-9,784	4.16	-2,353		14,330	I
7/1/25 17:01	6/30/25	AKBA	Akebia Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S.d	-212	3.76	-56		771	D
7/1/25 16:49	6/27/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	9	9	S	-322	14.56	-22		511	D
7/1/25 16:37	6/30/25	CLYM	Climb Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S.d	-27	1.22	-22		67	D
6/30/25 17:02	6/26/25	ZVRA	Zevra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-221	9.21	-24		43	D
6/26/25 20:00	6/24/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	5	S	-123	4.01	-31		549	D
6/25/25 18:52	6/23/25	OKUR	Onkure Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-1	2.38	0		17	D
6/24/25 16:08	6/24/25	ARVN	Arvinas, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-63	7.57	-8		319	D
6/23/25 13:50	6/20/25	RARE	Ultragenyx Pharmaceutical Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-90	37.39	-2		15	D
6/20/25 17:42	6/17/25	TYRA	Tyra Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.m	-628	10.23	-61		38	D
6/20/25 16:08	6/18/25	NKTX	Nkarta, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-3	1.79	-2		320	D
6/18/25 17:12	6/16/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.d	-165	10.43	-16	-100	0	D
6/17/25 16:11	6/13/25	CTMX	Cytomx Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S.dm	-220	2.69	-82		1,681	D
6/16/25 21:10	6/13/25	VNDA	Vanda Pharmaceuticals Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-32	4.59	-7		97	D
6/16/25 19:35	6/16/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	5	5	S.d	-132	9.22	-14		98	D
6/16/25 17:47	6/13/25	TGTX	Tg Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-369	36.94	-10		229	D
6/16/25 15:40	5/28/25	ANTX	An2 Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-218	1.09	-200		3,017	I
6/13/25 19:57	6/13/25	LTRN	Lantern Pharma Inc.	TX	Health	Drug	Pharmaceutical Preparations	2	4	S.m	-664	3.27	-203		2,232	I
6/11/25 16:15	6/9/25	HROW	Harrow, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.m	-924	30.59	-30		3,905	I
6/10/25 16:39	6/9/25	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	1	1	S.m	-210	31.52	-7		86	D
6/6/25 17:58	6/5/25	XENE	Xenon Pharmaceuticals Inc.	A1	Health	Drug	Pharmaceutical Preparations	1	1	S.d	0	30.33	0	0	7	D
6/6/25 16:47	6/5/25	KRON	Kronos Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-22	0.8678	-25		139	D
6/6/25 16:07	6/5/25	DYN	Dyne Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-74	13.35	-6		363	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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