Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	#o	#f	T	TVal	Price	Qty	oc	Own	H
12/23/25 21:42	12/19/25	OLMA	Olema Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	6	M.dm	19,855	19.35	1,026	999%	1,101	D
12/23/25 21:42	12/19/25	OLMA	Olema Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	6	S.dm	-19,855	19.35	-1,026		1,101	D
12/23/25 20:48	12/23/25	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	7	P	1,515	14.29	106	1	7,351	D
12/23/25 20:09	12/22/25	OKUR	Onkure Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-1	2.97	0		24	D
12/23/25 18:52	11/18/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	11	M.d	12,613	37.86	333	106	647	D
12/23/25 18:47	11/17/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	14	S.d	-1,849	15.65	-118		2,218	I
12/23/25 18:01	10/1/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	9	S.m	-23,671	64.19	-369		4,439	D
12/23/25 17:00	12/19/25	PHAT	Phathom Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	M.d	97	0.5136	189	268	260	D
12/23/25 16:41	12/19/25	IMNM	Immunome Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	P	9,684	21.67	447	10	5,062	D
12/23/25 16:37	12/19/25	CLNN	Clene Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.m	-1,790	6.69	-268		393	I
12/23/25 16:33	12/23/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	9	119	S.edm	-427,283	298.58	-1,431		726	D
12/23/25 16:31	11/24/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	37	S.dm	-106,298	74.95	-1,418		19,398	I
12/23/25 16:30	12/23/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	4	13	S.dm	-4,253	32.46	-131		55	D
12/23/25 16:30	12/19/25	ALZN	Alzamend Neuro, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	S.dm	-1,127	2.41	-468		82	D
12/23/25 16:26	12/22/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	8	34	M.d	13,959	37.46	373	98	752	D
12/23/25 16:24	12/23/25	EQ	Equillium, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	4	M.dm	284	1.16	244		127	D
12/23/25 16:24	12/23/25	EQ	Equillium, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	4	S.dm	-284	1.16	-244		127	D
12/23/25 16:16	12/19/25	FOLD	Amicus Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	14	S.dm	-5,885	9.39	-627		2,422	D
12/23/25 16:10	12/22/25	ALT	Altimmune, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	P.d	103	2.35	44	999%	48	D
12/23/25 16:02	11/24/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	29	M.dm	6,980	11.33	616	576	723	D
12/23/25 16:02	11/24/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	29	S.dm	-6,980	11.33	-616		723	D
12/23/25 16:02	12/19/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	2	4	M.dm	5,511	14.04	392	120	720	D
12/23/25 16:02	12/19/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.dm	-5,511	14.04	-392		720	D
12/23/25 14:55	12/19/25	CAPR	Capricor Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	4	1.39	3	27	14	D
12/23/25 14:04	11/24/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	1	32	M.dm	265	2.04	130		6	D
12/23/25 14:04	11/24/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	1	32	S.dm	-265	2.04	-130		6	D
12/23/25 13:21	12/16/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	7	38	S.dm	-6,809	4.59	-1,483		6,980	D
12/23/25 08:18	12/22/25	MAIA	Maia Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	14	P.dm	545	1.14	478	12	4,387	I
12/22/25 20:48	12/22/25	PGEN	Precigen, Inc.	VA	Health	Drug	Pharmaceutical Preparations	5	8	S.m	-27,933	3.93	-7,105		128,198	I
12/22/25 19:45	12/18/25	BNTC	Benitec Biopharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	P.m	20,539	13.45	1,528	511	1,827	I
12/22/25 17:52	12/22/25	ZYME	Zymeworks Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	M.d	1,284	8.71	148		133	D
12/22/25 17:52	12/22/25	ZYME	Zymeworks Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-1,284	8.71	-148		133	D
12/22/25 17:15	12/18/25	MRUS	Merus N.V.	P7	Health	Drug	Pharmaceutical Preparations	2	6	P.dm	54,345	95.34	570	1	72,024	I
12/22/25 16:15	12/19/25	LITS	Lite Strategy, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	P	1,067	1.38	773	26	3,775	D
12/22/25 16:09	12/19/25	RPRX	Royalty Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	3	11	S.m	-29,490	38.96	-757		2,057	I
12/22/25 16:04	9/25/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	18	M.d	13,149	32.33	407	21	2,373	D
12/22/25 08:15	12/18/25	HYPD	Hyperion Defi, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	P	398	3.05	130	54	371	M
12/22/25 07:07	11/7/25	EVMN	Evommune, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	P.d	70,017	16.00	4,376	45	14,016	I
12/22/25 07:00	12/18/25	RNXT	Renovorx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	5	P.m	46	0.8550	54	5	1,119	D
12/19/25 21:30	12/18/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	11	M.d	3,269	8.86	369	69	902	D
12/19/25 21:30	12/18/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	11	S.d	-3,269	8.86	-369		902	D
12/19/25 21:04	12/11/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	7	23	M.dm	540,156	17.37	31,098	29	138,783	D
12/19/25 21:04	12/11/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	7	23	S.dm	-540,156	17.37	-31,098		138,783	D
12/19/25 21:00	12/19/25	TYRA	Tyra Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	5	S.m	-9,570	18.34	-522		4,130	I
12/19/25 20:00	12/17/25	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	3	9	M.dm	3,826	5.13	746	24	3,802	D
12/19/25 20:00	12/17/25	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	3	9	S.dm	-3,826	5.13	-746		3,802	D
12/19/25 19:29	12/5/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	20	M.dm	59,874	33.65	1,779	18	11,566	D
12/19/25 19:29	12/5/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	20	S.dm	-59,874	33.65	-1,779		11,566	D
12/19/25 18:16	12/17/25	IRON	Disc Medicine, Inc.		Health	Drug	Pharmaceutical Preparations	5	12	S.dm	-99,197	77.20	-1,285		4,087	I
12/19/25 17:38	12/19/25	ORKA	Oruka Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	M.d	266	18.97	14		2	D
12/19/25 17:38	12/19/25	ORKA	Oruka Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-266	18.97	-14		2	D
12/19/25 17:17	12/1/25	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	4	6	S.dm	-1,646	5.43	-303		4,908	D
12/19/25 17:00	12/19/25	SVRA	Savara Inc	DE	Health	Drug	Pharmaceutical Preparations	3	3	S.d	-138	4.36	-32		2,722	D
12/19/25 17:00	12/17/25	ADTX	Aditxt, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	0	2.50	0		0	D
12/19/25 16:47	12/18/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	5	6	S.m	-2,414	87.46	-28		450	D
12/19/25 16:30	12/18/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	15	M.d	1,738	8.63	201	14	1,673	D
12/19/25 16:30	12/18/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	15	S.d	-1,738	8.63	-201		1,673	D
12/19/25 16:15	12/17/25	VTYX	Ventyx Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	M.d	463	2.19	212	8	2,862	D
12/19/25 16:15	12/18/25	VTYX	Ventyx Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.d	-463	2.19	-212		2,862	D
12/19/25 16:12	11/3/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	7	16	M.d	47,099	135.62	347	43	1,151	D
12/19/25 16:12	11/3/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	7	16	S.d	-47,099	135.62	-347		1,151	D
12/19/25 16:05	12/17/25	SLGL	Sol-Gel Technologies Ltd.	L3	Health	Drug	Pharmaceutical Preparations	1	6	P.m	646	37.65	17	5	385	I
12/19/25 16:05	12/17/25	PVLA	Palvella Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	4	M.d	856	49.73	17		0	D
12/19/25 16:05	12/17/25	PVLA	Palvella Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	4	S.d	-856	49.73	-17	-100	0	D
12/19/25 15:43	12/18/25	MNPR	Monopar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	4	4	S.d	-35,344	62.18	-568		681	D
12/19/25 06:05	12/18/25	GLSI	Greenwich Lifesciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	4	P	201	9.30	22	0	5,592	D
12/18/25 20:05	12/16/25	SRPT	Sarepta Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-294	22.31	-13		193	D
12/18/25 18:54	10/1/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	10	M.d	2,402	22.93	105	8	1,433	D
12/18/25 18:54	10/1/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	10	S.d	-2,402	22.93	-105		1,433	D
12/18/25 18:08	11/3/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	11	S.d	-1,004	7.51	-134		172	D
12/18/25 17:35	12/16/25	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	20	S.dm	-10,467	17.60	-595		4,178	D
12/18/25 17:23	12/17/25	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	3	9	M.dm	1,404	21.13	66	23	354	D
12/18/25 17:23	12/17/25	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	3	9	S.dm	-1,404	21.13	-66		354	D
12/18/25 16:47	12/16/25	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	5	13	S.dm	-574	9.27	-62		599	D
12/18/25 16:34	12/16/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	2	6	S.d	-454	18.08	-25		45	D
12/18/25 16:19	12/16/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	5	10	M.d	3,859	132.52	29	14	240	D
12/18/25 16:19	12/16/25	ORGO	Organogenesis Holdings Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	4	S.m	-3,796	4.31	-881		12,249	D
12/18/25 16:11	12/17/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	8	S.d	-1,728	25.32	-68		1,284	M
12/18/25 16:10	12/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	S	-231	3.65	-63		2,331	D
12/18/25 16:06	12/16/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	7	S.d	-2,169	22.32	-97		534	D
12/18/25 16:04	12/16/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	6	13	S.d	-24,465	23.41	-1,045		788	D
12/18/25 15:13	12/16/25	APLT	Applied Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-5	0.1120	-43		65	D
12/17/25 19:21	12/15/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	13	M.dm	2,375	6.05	392	58	1,064	D
12/17/25 19:21	12/16/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	13	S.dm	-2,375	6.05	-392		1,064	D
12/17/25 18:28	12/2/25	HOWL	Werewolf Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	30	S.m	-6,109	1.14	-5,337		17,018	I
12/17/25 17:53	11/3/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	9	25	S.dm	-9,385	20.66	-454		1,747	D
12/17/25 17:25	12/5/25	HRMY	Harmony Biosciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	6	M.d	2,696	20.07	134		21	D
12/17/25 17:25	12/5/25	HRMY	Harmony Biosciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	6	S.d	-2,696	20.07	-134		21	D
12/17/25 16:58	12/15/25	SPRB	Spruce Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	10	M.dm	19	0.9454	20	571	24	D
12/17/25 16:47	12/10/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	4	11	M.dm	45,974	308.95	149	0	52,514	D
12/17/25 16:47	12/10/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	4	11	S.dm	-45,974	308.95	-149	0	52,514	D
12/17/25 16:38	12/15/25	KNSA	Kiniksa Pharmaceuticals International, Plc		Health	Drug	Pharmaceutical Preparations	6	25	M.dm	25,803	23.95	1,077		399	D
12/17/25 16:38	12/15/25	KNSA	Kiniksa Pharmaceuticals International, Plc		Health	Drug	Pharmaceutical Preparations	6	25	S.dm	-25,803	23.95	-1,077		399	D
12/17/25 16:23	12/15/25	LFVN	Lifevantage Corp		Health	Drug	Pharmaceutical Preparations	2	3	P	336	6.80	49	28	229	D
12/17/25 16:14	12/16/25	RZLT	Rezolute, Inc.	NV	Health	Drug	Pharmaceutical Preparations	5	5	P	207	1.69	123	8	1,679	D
12/17/25 16:10	12/8/25	FULC	Fulcrum Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-58,587	13.97	-4,194		6,549	I
12/17/25 16:05	12/15/25	VERA	Vera Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	10	M.d	2,652	28.00	95	2	5,530	D
12/17/25 16:05	12/15/25	VERA	Vera Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	10	S.d	-2,652	28.00	-95		5,530	D
12/16/25 20:50	12/12/25	HROW	Harrow, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	M.d	948	3.95	240	7	3,797	D
12/16/25 18:34	12/15/25	SILO	Silo Pharma, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	3	P.m	8	0.4030	19	10	217	D
12/16/25 18:27	12/12/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	18	M.dm	49,900	53.69	929	15	7,277	D
12/16/25 18:27	12/15/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	18	S.dm	-49,900	53.69	-929		7,277	D
12/16/25 18:00	12/12/25	CLRB	Cellectar Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-1	3.70	0		0	I
12/16/25 17:41	12/15/25	SXTP	60 Degrees Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	P.m	20	0.8820	23	61	60	D
12/16/25 17:00	12/12/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	11	25	M.d	1,948	9.33	209	3	6,802	D
12/16/25 17:00	12/12/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	11	25	S.d	-1,948	9.33	-209		6,802	D
12/16/25 16:42	12/11/25	ELAN	Elanco Animal Health Inc		Health	Drug	Pharmaceutical Preparations	4	4	P	938	21.59	43	2	2,348	D
12/16/25 16:23	12/1/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	5	11	M.dm	11,722	25.73	456	160	740	D
12/16/25 16:23	12/1/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	5	11	S.dm	-11,722	25.73	-456		740	D
12/16/25 14:59	12/12/25	NATR	Natures Sunshine Products Inc	UT	Health	Drug	Pharmaceutical Preparations	6	10	S	-401	9.52	-42		456	D
12/16/25 09:30	12/15/25	RLMD	Relmada Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	4	6	P.d	2,358	2.27	1,038	53	3,006	D
12/16/25 08:56	12/15/25	ANIX	Anixa Biosciences Inc	DE	Health	Drug	Pharmaceutical Preparations	2	2	M.d	631	2.92	216	16	1,580	D
12/15/25 20:02	12/14/25	BTAI	Bioxcel Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	6	M.dm	0	0.00	4	1	541	D
12/15/25 19:55	12/11/25	CLYM	Climb Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P.dm	755	2.40	315	3	11,294	I
12/15/25 17:24	12/15/25	ZNTL	Zentalis Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	1	1	S	-9,975	1.33	-7,500		6,460	I
12/15/25 16:51	12/11/25	PAHC	Phibro Animal Health Corp	DE	Health	Drug	Pharmaceutical Preparations	1	14	S.dm	-8,431	42.77	-197		91	I
12/15/25 16:38	12/12/25	OGEN	Oragenics Inc	FL	Health	Drug	Pharmaceutical Preparations	1	1	S.d	0	0.9429	0		35	D
12/15/25 16:32	12/11/25	WVE	Wave Life Sciences Ltd.	X0	Health	Drug	Pharmaceutical Preparations	10	17	P.dm	48,075	13.71	3,507	10	36,993	I
12/15/25 16:30	12/11/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	12	M.dm	7,312	64.63	113		29	D
12/15/25 16:30	12/11/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	12	S.dm	-7,312	64.63	-113		29	D
12/15/25 16:18	10/24/25	CRBP	Corbus Pharmaceuticals Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	7	M.dm	1,236	10.90	113	5	2,563	D
12/15/25 16:18	10/24/25	CRBP	Corbus Pharmaceuticals Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	7	S.dm	-1,236	10.90	-113		2,563	D
12/15/25 16:15	12/11/25	BMEA	Biomea Fusion, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	P.m	197	1.09	180	7	2,688	D
12/12/25 20:30	12/11/25	AARD	Aardvark Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	P.d	155	12.43	12	0	3,135	D
12/12/25 18:00	12/12/25	TTRX	Turn Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	8	P.m	308	3.99	77	5	1,520	D
12/12/25 17:30	12/10/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	1	S	-116	9.99	-12		81	D
12/12/25 17:17	12/12/25	IMVT	Immunovant, Inc.	D0	Health	Drug	Pharmaceutical Preparations	1	1	P	350,000	21.00	16,667	17	113,317	D
12/12/25 16:40	12/10/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	13	M.d	46,577	233.17	200	10	2,148	D
12/12/25 16:40	12/10/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	13	S.d	-46,577	233.17	-200		2,148	D
12/12/25 07:16	12/11/25	FBLG	Fibrobiologics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	48	0.3400	140		140	D
12/11/25 21:47	12/9/25	PCRX	Pacira Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	M.dm	1,400	21.20	66	39	235	D
12/11/25 21:47	12/9/25	PCRX	Pacira Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.dm	-1,400	21.20	-66		235	D
12/11/25 20:50	8/21/25	GNLX	Genelux Corp	DE	Health	Drug	Pharmaceutical Preparations	5	5	S.m	-156	4.16	-37		1,402	D
12/11/25 17:35	12/9/25	IRD	Opus Genetics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-8,600	2.15	-4,000		5,492	D
12/11/25 17:19	12/9/25	JAZZ	Jazz Pharmaceuticals Plc	L2	Health	Drug	Pharmaceutical Preparations	6	13	S.dm	-34,125	155.15	-220		537	D
12/11/25 16:27	11/7/25	REGN	Regeneron Pharmaceuticals, Inc.	NY	Health	Drug	Pharmaceutical Preparations	7	9	S.dm	-215,212	556.60	-387		1,921	D
12/11/25 16:21	12/9/25	BIOA	Bioage Labs, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	4	M.d	1,319	7.59	174		0	D
12/11/25 16:21	12/9/25	BIOA	Bioage Labs, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	4	S.d	-1,319	7.59	-174	-100	0	D
12/11/25 12:10	12/10/25	RARE	Ultragenyx Pharmaceutical Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S	-362	32.87	-11		98	D
12/11/25 08:31	12/10/25	APRE	Aprea Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P.d	31	1.17	26	10	284	D
12/10/25 20:51	12/8/25	XCUR	Exicure, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-3,774	8.71	-433	-100	0	D
12/10/25 18:49	12/10/25	IMMX	Immix Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P.d	10	6.62	2	0	1,884	D
12/10/25 18:48	11/18/25	TENX	Tenax Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	6	P.dm	204	8.31	25	999%	25	D
12/10/25 17:05	12/9/25	ELTX	Elicio Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	2	4.41	0	95	1	D
12/10/25 16:56	12/9/25	SNSE	Sensei Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	6	S.dm	-580	10.24	-57		323	D
12/10/25 16:56	12/9/25	SNSE	Sensei Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	6	M.dm	580	10.24	57	21	323	D
12/10/25 16:32	11/6/25	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	4	6	S.d	-4,593	33.15	-139		348	D
12/10/25 16:29	12/8/25	MLTX	Moonlake Immunotherapeutics	E9	Health	Drug	Pharmaceutical Preparations	4	4	S.m	-52,954	7.66	-6,914		8,475	D
12/10/25 16:24	12/8/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	24	S.dm	-6,572	19.61	-335		488	D
12/9/25 19:40	12/5/25	XENE	Xenon Pharmaceuticals Inc.	A1	Health	Drug	Pharmaceutical Preparations	1	4	S.dm	-2,343	31.12	-75		46	D
12/9/25 19:13	12/5/25	ALMS	Alumis Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	12	P.m	19,952	6.64	3,006	6	53,091	I
12/9/25 19:07	12/9/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	3	13	S.d	-4,160	18.74	-222		427	D
12/9/25 18:16	11/21/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	21	M.dm	695	2.81	247	42	830	D
12/9/25 18:16	11/24/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	21	S.dm	-695	2.81	-247		830	D
12/9/25 18:01	10/7/25	EBS	Emergent Biosolutions Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	5	S.d	-972	9.28	-105		452	D
12/9/25 16:36	11/13/25	MRVI	Maravai Lifesciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	P.m	1,880	3.32	567	26	2,732	I
12/8/25 20:05	12/8/25	ANVS	Annovis Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	8	P.d	2,816	2.27	1,239	44	4,024	D
12/8/25 17:15	11/21/25	DMAC	Diamedica Therapeutics Inc.	Z4	Health	Drug	Pharmaceutical Preparations	2	2	M.dm	7,658	7.14	1,073	14	8,914	D
12/8/25 16:30	12/4/25	XOMA	Xoma Royalty Corp	NV	Health	Drug	Pharmaceutical Preparations	1	1	P	2,505	25.05	100	99	201	D
12/8/25 16:30	12/4/25	CBIO	Crescent Biopharma, Inc.	E9	Health	Drug	Pharmaceutical Preparations	1	1	P.d	18,238	13.41	1,360	98	2,748	I
12/8/25 16:07	12/4/25	RNAC	Cartesian Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P.d	231	6.15	38	47	117	D
12/5/25 20:00	12/4/25	DNTH	Dianthus Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	2	4	M.dm	11,450	26.44	433		4	D
12/5/25 20:00	12/4/25	DNTH	Dianthus Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.dm	-11,450	26.44	-433		4	D
12/5/25 18:53	12/5/25	ENTA	Enanta Pharmaceuticals Inc		Health	Drug	Pharmaceutical Preparations	7	9	S	-183	14.22	-13		1,346	D
12/5/25 18:02	12/3/25	TBPH	Theravance Biopharma, Inc.	CA	Health	Drug	Pharmaceutical Preparations	2	4	S.d	-3,050	18.53	-165		338	D
12/5/25 16:21	12/3/25	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	1	7	M.d	1,053	26.65	39	115	74	D
12/5/25 16:21	12/3/25	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	1	7	S.d	-1,053	26.65	-39		74	D
12/5/25 16:16	12/3/25	VRTX	Vertex Pharmaceuticals Inc / Ma	MA	Health	Drug	Pharmaceutical Preparations	5	9	S.dm	-82,886	279.84	-296		141	D
12/5/25 16:11	12/5/25	DYN	Dyne Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-76	20.72	-4		451	D
12/4/25 19:39	12/2/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	6	M.dm	41,202	71.21	579	9	7,352	D
12/4/25 19:39	12/2/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	6	S.dm	-41,202	71.21	-579		7,352	D
12/4/25 19:00	12/2/25	QTTB	Q32 Bio Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-109	3.46	-32		139	D
12/4/25 17:15	12/2/25	SONN	Sonnet Biotherapeutics Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	0	0.00	250		0	D
12/4/25 16:50	12/2/25	ACRS	Aclaris Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	0	0.00	27		27	D
12/3/25 21:52	12/1/25	SYRE	Spyre Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S	-1,485	24.75	-60		702	D
12/3/25 21:19	12/2/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	5	25	M.dm	23,390	57.98	403	16	2,915	M
12/3/25 21:19	12/2/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	5	25	S.dm	-23,390	57.98	-403		2,915	M
12/3/25 20:00	12/1/25	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	6	M.d	894	19.16	47	122	85	D
12/3/25 20:00	12/1/25	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	6	S.d	-894	19.16	-47		85	D
12/3/25 19:01	12/1/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	12	41	S.dm	-62,474	63.08	-990		715	I
12/3/25 17:02	12/1/25	NUVB	Nuvation Bio Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	14	M.dm	8,069	4.54	1,778		42	D
12/3/25 17:02	12/1/25	NUVB	Nuvation Bio Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	14	S.dm	-8,069	4.54	-1,778		42	D
12/3/25 16:30	12/1/25	ANNX	Annexon, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	P.m	8,838	3.73	2,368	32	9,812	D
12/3/25 16:16	12/2/25	TRVI	Trevi Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	2	0.5110	4	19	26	D
12/2/25 16:43	11/28/25	PBH	Prestige Consumer Healthcare Inc.		Health	Drug	Pharmaceutical Preparations	1	1	S.m	-60	60.00	-1		42	D
12/2/25 16:34	11/28/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	8	30	M.d	5,438	19.50	279	7	4,472	D
12/2/25 16:34	12/1/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	8	30	S.d	-5,438	19.50	-279		4,472	D
12/1/25 17:17	11/26/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	7	8	M.d	287	10.76	27	21	151	D
12/1/25 16:15	11/26/25	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	2	3	P.d	7,874	176.18	45		13	D
12/1/25 16:10	11/26/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	5	10	M.dm	31,767	321.41	99	100	198	D
12/1/25 16:07	11/26/25	CVRX	Cvrx, Inc.	NJ	Health	Drug	Pharmaceutical Preparations	1	4	S.m	-637	10.18	-63		4,051	I
12/1/25 09:07	11/28/25	KTTA	Pasithea Therapeutics Corp.	DE	Health	Drug	Pharmaceutical Preparations	3	3	P	150	0.7500	200	184	309	D
11/28/25 17:38	11/25/25	BHC	Bausch Health Companies Inc.	NJ	Health	Drug	Pharmaceutical Preparations	1	1	P	15,625	6.25	2,500	4	73,256	I
11/28/25 09:00	11/26/25	COCP	Cocrystal Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	P	23	0.9495	24	1	1,731	I
11/28/25 06:03	11/25/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	11	M.d	7,019	16.46	427	21	2,436	D
11/26/25 16:02	11/24/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	6	8	S	-973	11.45	-85		4,441	D
11/26/25 16:00	11/13/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	2	29	S.e	-1,910,772	560.23	-3,411		95,498	D
11/26/25 14:58	11/26/25	ABCL	Abcellera Biologics Inc.	A1	Health	Drug	Pharmaceutical Preparations	1	1	P	178	3.57	50	28	226	D
11/25/25 20:30	11/25/25	NKTR	Nektar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	3	3	S.d	-217	54.28	-4		95	D
11/25/25 19:00	11/25/25	VRCA	Verrica Pharmaceuticals Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	5	P.d	17,973	4.24	4,236	108	8,148	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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