Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	#o	#f	T	TVal	Price	Qty	oc	Own	H
12/31/25 17:45	12/29/25	SLGL	Sol-Gel Technologies Ltd.	L3	Health	Drug	Pharmaceutical Preparations	1	8	P.m	3,550	41.10	86	24	454	I
12/31/25 17:05	11/7/25	REGN	Regeneron Pharmaceuticals, Inc.	NY	Health	Drug	Pharmaceutical Preparations	8	10	S.dm	-220,002	555.75	-396		1,954	D
12/31/25 16:33	12/9/25	IRD	Opus Genetics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-8,924	2.14	-4,164		7,500	D
12/31/25 16:10	12/30/25	COCP	Cocrystal Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	4	P.m	105	0.9660	109	6	1,816	I
12/31/25 16:05	12/29/25	CVKD	Cadrenal Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	7	S.m	-262	11.07	-24		419	D
12/31/25 12:10	12/29/25	CLNN	Clene Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	4	S.dm	-1,937	6.64	-292		796	I
12/30/25 18:47	12/19/25	IMNM	Immunome Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	5	P	9,784	21.66	452	10	5,062	D
12/30/25 17:54	12/23/25	ALZN	Alzamend Neuro, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	S.dm	-947	2.43	-390		82	D
12/30/25 17:46	10/1/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	12	S.dm	-28,091	58.56	-480		4,439	D
12/30/25 17:41	12/26/25	MRUS	Merus N.V.	P7	Health	Drug	Pharmaceutical Preparations	2	8	P.edm	235,854	3.01	78,308		72,840	I
12/30/25 17:00	12/29/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	11	34	M.d	1,948	7.05	277	4	6,832	D
12/30/25 16:34	12/29/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	8	33	S.d	-13,428	37.02	-363		746	D
12/30/25 16:33	12/26/25	CYPH	Cypherpunk Technologies Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	M.d	5,069	2.99	1,697		180	D
12/30/25 16:31	12/23/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	9	115	S.edm	-431,093	301.88	-1,428		726	D
12/30/25 16:17	12/30/25	MBIO	Mustang Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	0	0.9639	0		1	D
12/30/25 16:12	12/29/25	CTNM	Contineum Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	M.d	111	9.73	11	7	171	D
12/30/25 16:12	12/29/25	CTNM	Contineum Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S.d	-111	9.73	-11		171	D
12/30/25 16:02	9/30/25	VREOF	Vireo Growth Inc.	A1	Health	Drug	Pharmaceutical Preparations	1	1	M.d	0	0.00	200		138	D
12/30/25 16:01	12/26/25	HYPD	Hyperion Defi, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	P.m	511	3.17	161	77	371	M
12/30/25 16:01	12/26/25	COGT	Cogent Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	S	-12,179	38.71	-315		515	D
12/30/25 16:00	11/13/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	2	29	S.e	-1,539,328	521.37	-2,952		95,034	D
12/30/25 13:49	12/29/25	RARE	Ultragenyx Pharmaceutical Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S	-365	32.88	-11		149	D
12/29/25 21:55	12/19/25	OLMA	Olema Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	7	M.dm	19,937	19.38	1,029	111	1,959	D
12/29/25 21:55	12/19/25	OLMA	Olema Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	7	S.dm	-19,937	19.38	-1,029		1,959	D
12/29/25 21:11	12/1/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	7	17	M.dm	16,624	26.90	618	198	930	D
12/29/25 21:11	12/1/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	7	17	S.dm	-16,624	26.90	-618		930	D
12/29/25 21:00	12/11/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	8	27	M.dm	558,121	17.19	32,472	30	139,172	D
12/29/25 21:00	12/11/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	8	27	S.dm	-558,121	17.19	-32,472		139,172	D
12/29/25 20:50	12/17/25	IRON	Disc Medicine, Inc.		Health	Drug	Pharmaceutical Preparations	5	13	S.dm	-99,228	77.04	-1,288		4,090	I
12/29/25 20:44	12/5/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	19	M.dm	59,598	34.71	1,717	18	11,516	D
12/29/25 20:44	12/5/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	19	S.dm	-59,598	34.71	-1,717		11,516	D
12/29/25 20:06	12/22/25	RIGL	Rigel Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	140	21.51	7	11	64	D
12/29/25 19:31	12/23/25	BNTC	Benitec Biopharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	3	P.m	22,442	13.42	1,672	948	1,848	I
12/29/25 18:42	12/22/25	EOLS	Evolus, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-92	7.15	-13		711	D
12/29/25 17:58	12/24/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	6	27	M.dm	26,086	23.75	1,098	53	3,180	D
12/29/25 17:27	12/2/25	HOWL	Werewolf Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	31	S.m	-6,294	1.12	-5,628		17,018	I
12/29/25 17:18	11/24/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	29	M.dm	6,355	10.72	593	368	754	D
12/29/25 17:18	11/24/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	29	S.dm	-6,355	10.72	-593		754	D
12/29/25 17:14	12/23/25	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	1	2	M.dm	6,651	22.94	290		15	D
12/29/25 17:14	12/23/25	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	1	2	S.dm	-6,651	22.94	-290		15	D
12/29/25 16:58	12/26/25	RPRX	Royalty Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	3	12	S.m	-30,277	38.97	-777		2,057	I
12/29/25 16:36	10/1/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	8	M.d	1,521	16.40	93	6	1,528	D
12/29/25 16:36	10/1/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	8	S.d	-1,521	16.40	-93		1,528	D
12/29/25 16:30	12/24/25	PTN	Palatin Technologies Inc	NJ	Health	Drug	Pharmaceutical Preparations	1	1	S	-9	16.75	-1		63	D
12/29/25 16:30	12/29/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S	-205	5.10	-40		1,252	D
12/29/25 16:23	12/23/25	TXMD	Therapeuticsmd, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	1	P	14	1.67	8	29	38	D
12/29/25 16:15	12/23/25	DVAX	Dynavax Technologies Corp	DE	Health	Drug	Pharmaceutical Preparations	5	6	M.dm	706	2.57	275	90	580	D
12/29/25 16:10	12/22/25	ALT	Altimmune, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	P.d	105	2.37	44	999%	49	D
12/29/25 12:24	12/24/25	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	6	14	S.dm	-575	9.27	-62		708	D
12/29/25 12:15	12/26/25	MNPR	Monopar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	2	2	P	449	67.79	7	182	10	D
12/29/25 11:40	11/24/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	1	34	M.dm	276	2.00	138		6	D
12/29/25 11:40	11/24/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	1	34	S.dm	-276	2.00	-138		6	D
12/29/25 08:10	12/23/25	PHIO	Phio Pharmaceuticals Corp.	DE	Health	Drug	Pharmaceutical Preparations	1	3	P	17	1.14	15	6	286	D
12/23/25 20:48	12/23/25	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P	195	13.30	15	7	239	D
12/23/25 20:09	12/22/25	OKUR	Onkure Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-1	2.97	0		24	D
12/23/25 18:52	11/18/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	11	M.d	12,613	37.86	333	106	647	D
12/23/25 18:47	11/17/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	10	S.d	-1,619	15.57	-104		2,193	I
12/23/25 17:00	12/19/25	PHAT	Phathom Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	M.d	97	0.9791	99	62	260	D
12/23/25 16:31	11/24/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	33	S.dm	-103,318	76.24	-1,355		19,398	I
12/23/25 16:30	12/23/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	4	11	S.dm	-3,944	33.49	-118		55	D
12/23/25 16:24	12/23/25	EQ	Equillium, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	4	M.dm	284	1.16	244		127	D
12/23/25 16:24	12/23/25	EQ	Equillium, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	4	S.dm	-284	1.16	-244		127	D
12/23/25 16:16	12/19/25	FOLD	Amicus Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	14	S.dm	-5,885	9.39	-627		2,422	D
12/23/25 16:02	12/19/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	2	4	M.dm	5,511	14.04	392	120	720	D
12/23/25 16:02	12/19/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.dm	-5,511	14.04	-392		720	D
12/23/25 14:55	12/19/25	CAPR	Capricor Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	4	1.39	3	27	14	D
12/23/25 13:21	12/16/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	7	38	S.dm	-6,809	4.59	-1,483		6,980	D
12/23/25 08:18	12/22/25	MAIA	Maia Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	13	P.dm	520	1.13	458	12	4,387	I
12/22/25 20:48	12/22/25	PGEN	Precigen, Inc.	VA	Health	Drug	Pharmaceutical Preparations	2	3	S.m	-21,090	4.13	-5,102		124,057	I
12/22/25 17:52	12/22/25	ZYME	Zymeworks Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	M.d	1,284	8.71	148		133	D
12/22/25 17:52	12/22/25	ZYME	Zymeworks Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-1,284	8.71	-148		133	D
12/22/25 16:15	12/19/25	LITS	Lite Strategy, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	P	1,067	1.38	773	26	3,775	D
12/22/25 16:04	12/19/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	11	M.d	8,314	31.16	267	13	2,362	D
12/22/25 16:04	12/19/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	11	S.d	-8,314	31.16	-267		2,362	D
12/22/25 07:07	11/7/25	EVMN	Evommune, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	P.d	70,017	16.00	4,376	45	14,016	I
12/22/25 07:00	12/18/25	RNXT	Renovorx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	5	P.m	46	0.8550	54	5	1,119	D
12/19/25 21:30	12/18/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	11	M.d	3,269	8.86	369	69	902	D
12/19/25 21:30	12/18/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	11	S.d	-3,269	8.86	-369		902	D
12/19/25 21:00	12/19/25	TYRA	Tyra Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	5	S.m	-9,570	18.34	-522		4,130	I
12/19/25 20:00	12/17/25	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	3	9	M.dm	3,826	5.13	746	24	3,802	D
12/19/25 20:00	12/17/25	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	3	9	S.dm	-3,826	5.13	-746		3,802	D
12/19/25 17:38	12/19/25	ORKA	Oruka Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	M.d	266	18.97	14		2	D
12/19/25 17:38	12/19/25	ORKA	Oruka Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-266	18.97	-14		2	D
12/19/25 17:17	12/1/25	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	4	6	S.dm	-1,646	5.43	-303		4,908	D
12/19/25 17:00	12/19/25	SVRA	Savara Inc	DE	Health	Drug	Pharmaceutical Preparations	3	3	S.d	-138	4.36	-32		2,722	D
12/19/25 17:00	12/17/25	ADTX	Aditxt, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	0	2.50	0		0	D
12/19/25 16:47	12/18/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	5	6	S.m	-2,414	87.46	-28		450	D
12/19/25 16:30	12/18/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	9	M.d	1,040	8.43	123	17	847	D
12/19/25 16:30	12/18/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	9	S.d	-1,040	8.43	-123		847	D
12/19/25 16:15	12/17/25	VTYX	Ventyx Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	M.d	463	2.19	212	8	2,862	D
12/19/25 16:15	12/18/25	VTYX	Ventyx Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.d	-463	2.19	-212		2,862	D
12/19/25 16:12	11/3/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	7	16	M.d	47,099	135.62	347	43	1,151	D
12/19/25 16:12	11/3/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	7	16	S.d	-47,099	135.62	-347		1,151	D
12/19/25 16:05	12/17/25	PVLA	Palvella Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	4	M.d	856	49.73	17		0	D
12/19/25 16:05	12/17/25	PVLA	Palvella Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	4	S.d	-856	49.73	-17	-100	0	D
12/19/25 06:05	12/18/25	GLSI	Greenwich Lifesciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	4	P	201	9.30	22	0	5,592	D
12/18/25 20:05	12/16/25	SRPT	Sarepta Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-294	22.31	-13		193	D
12/18/25 18:08	11/3/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	11	S.d	-1,004	7.51	-134		172	D
12/18/25 17:35	12/16/25	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	19	S.dm	-10,430	17.63	-592		4,178	D
12/18/25 17:23	12/17/25	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	3	8	M.dm	1,391	21.09	66	23	353	D
12/18/25 17:23	12/17/25	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	3	8	S.dm	-1,391	21.09	-66		353	D
12/18/25 16:34	12/16/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	2	6	S.d	-454	18.08	-25		45	D
12/18/25 16:19	12/16/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	5	10	M.d	3,859	132.52	29	14	240	D
12/18/25 16:19	12/16/25	ORGO	Organogenesis Holdings Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	4	S.m	-3,796	4.31	-881		12,249	D
12/18/25 16:11	12/17/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	8	S.d	-1,728	25.32	-68		1,284	M
12/18/25 16:10	12/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	S	-231	3.65	-63		2,331	D
12/18/25 16:06	12/16/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	S.d	-1,467	22.20	-66		499	D
12/18/25 16:04	12/16/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	6	13	S.d	-24,465	23.41	-1,045		788	D
12/18/25 15:13	12/16/25	APLT	Applied Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-5	0.1120	-43		65	D
12/17/25 19:21	12/15/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	12	M.d	1,321	4.33	305	40	1,064	D
12/17/25 19:21	12/16/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	12	S.d	-1,321	4.33	-305		1,064	D
12/17/25 17:53	11/3/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	9	25	S.dm	-9,385	20.66	-454		1,747	D
12/17/25 17:25	12/5/25	HRMY	Harmony Biosciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	5	M.d	2,696	30.17	89		0	D
12/17/25 17:25	12/5/25	HRMY	Harmony Biosciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	5	S.d	-2,696	30.17	-89	-100	0	D
12/17/25 16:58	12/15/25	SPRB	Spruce Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	10	M.dm	19	0.9454	20	571	24	D
12/17/25 16:47	12/10/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	4	11	M.dm	45,974	308.95	149	0	52,514	D
12/17/25 16:47	12/10/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	4	11	S.dm	-45,974	308.95	-149	0	52,514	D
12/17/25 16:38	12/15/25	KNSA	Kiniksa Pharmaceuticals International, Plc		Health	Drug	Pharmaceutical Preparations	6	23	M.dm	23,441	23.60	993		393	D
12/17/25 16:38	12/15/25	KNSA	Kiniksa Pharmaceuticals International, Plc		Health	Drug	Pharmaceutical Preparations	6	23	S.dm	-23,441	23.60	-993		393	D
12/17/25 16:23	12/15/25	LFVN	Lifevantage Corp		Health	Drug	Pharmaceutical Preparations	2	3	P	336	6.80	49	28	229	D
12/17/25 16:14	12/16/25	RZLT	Rezolute, Inc.	NV	Health	Drug	Pharmaceutical Preparations	5	5	P	207	1.69	123	8	1,679	D
12/17/25 16:10	12/8/25	FULC	Fulcrum Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-58,587	13.97	-4,194		6,549	I
12/17/25 16:05	12/15/25	VERA	Vera Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	10	M.d	2,652	28.00	95	2	5,530	D
12/17/25 16:05	12/15/25	VERA	Vera Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	10	S.d	-2,652	28.00	-95		5,530	D
12/16/25 20:50	12/12/25	HROW	Harrow, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	M.d	948	3.95	240	7	3,797	D
12/16/25 18:34	12/15/25	SILO	Silo Pharma, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	3	P.m	8	0.4030	19	10	217	D
12/16/25 18:27	12/12/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	18	M.dm	49,900	53.69	929	15	7,277	D
12/16/25 18:27	12/15/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	18	S.dm	-49,900	53.69	-929		7,277	D
12/16/25 18:00	12/12/25	CLRB	Cellectar Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-1	3.70	0		0	I
12/16/25 17:41	12/15/25	SXTP	60 Degrees Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	P.m	20	0.8820	23	61	60	D
12/16/25 16:42	12/11/25	ELAN	Elanco Animal Health Inc		Health	Drug	Pharmaceutical Preparations	4	4	P	938	21.59	43	2	2,348	D
12/16/25 14:59	12/12/25	NATR	Natures Sunshine Products Inc	UT	Health	Drug	Pharmaceutical Preparations	6	10	S	-401	9.52	-42		456	D
12/16/25 09:30	12/15/25	RLMD	Relmada Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	4	6	P.d	2,358	2.27	1,038	53	3,006	D
12/16/25 08:56	12/15/25	ANIX	Anixa Biosciences Inc	DE	Health	Drug	Pharmaceutical Preparations	2	2	M.d	631	2.92	216	16	1,580	D
12/15/25 20:02	12/14/25	BTAI	Bioxcel Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	5	M.dm	0	0.00	2	0	541	D
12/15/25 19:55	12/11/25	CLYM	Climb Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P.dm	755	2.40	315	3	11,294	I
12/15/25 17:24	12/15/25	ZNTL	Zentalis Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	1	1	S	-9,975	1.33	-7,500		6,460	I
12/15/25 16:51	12/11/25	PAHC	Phibro Animal Health Corp	DE	Health	Drug	Pharmaceutical Preparations	1	13	S.dm	-7,597	43.05	-176		91	I
12/15/25 16:38	12/12/25	OGEN	Oragenics Inc	FL	Health	Drug	Pharmaceutical Preparations	1	1	S.d	0	0.9429	0		35	D
12/15/25 16:32	12/11/25	WVE	Wave Life Sciences Ltd.	X0	Health	Drug	Pharmaceutical Preparations	10	17	P.dm	48,075	13.71	3,507	10	36,993	I
12/15/25 16:30	12/11/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	12	M.dm	7,312	64.63	113		29	D
12/15/25 16:30	12/11/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	12	S.dm	-7,312	64.63	-113		29	D
12/15/25 16:18	10/24/25	CRBP	Corbus Pharmaceuticals Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	7	M.dm	1,236	10.90	113	5	2,563	D
12/15/25 16:18	10/24/25	CRBP	Corbus Pharmaceuticals Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	7	S.dm	-1,236	10.90	-113		2,563	D
12/15/25 16:15	12/11/25	BMEA	Biomea Fusion, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	P.m	197	1.09	180	7	2,688	D
12/12/25 20:30	12/11/25	AARD	Aardvark Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	P.d	155	12.43	12	0	3,135	D
12/12/25 18:00	12/12/25	TTRX	Turn Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	8	P.m	308	3.99	77	5	1,520	D
12/12/25 17:30	12/10/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	1	S	-116	9.99	-12		81	D
12/12/25 17:17	12/12/25	IMVT	Immunovant, Inc.	D0	Health	Drug	Pharmaceutical Preparations	1	1	P	350,000	21.00	16,667	17	113,317	D
12/12/25 16:40	12/10/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	13	M.d	46,577	233.17	200	10	2,148	D
12/12/25 16:40	12/10/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	13	S.d	-46,577	233.17	-200		2,148	D
12/12/25 07:16	12/11/25	FBLG	Fibrobiologics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	48	0.3400	140		140	D
12/11/25 21:47	12/9/25	PCRX	Pacira Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	M.dm	1,400	21.20	66	39	235	D
12/11/25 21:47	12/9/25	PCRX	Pacira Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.dm	-1,400	21.20	-66		235	D
12/11/25 20:50	8/21/25	GNLX	Genelux Corp	DE	Health	Drug	Pharmaceutical Preparations	5	5	S.m	-156	4.16	-37		1,402	D
12/11/25 17:19	12/9/25	JAZZ	Jazz Pharmaceuticals Plc	L2	Health	Drug	Pharmaceutical Preparations	6	13	S.dm	-34,125	155.15	-220		537	D
12/11/25 16:21	12/9/25	BIOA	Bioage Labs, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	4	M.d	1,319	7.59	174		0	D
12/11/25 16:21	12/9/25	BIOA	Bioage Labs, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	4	S.d	-1,319	7.59	-174	-100	0	D
12/11/25 08:31	12/10/25	APRE	Aprea Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P.d	31	1.17	26	10	284	D
12/10/25 20:51	12/8/25	XCUR	Exicure, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-3,774	8.71	-433	-100	0	D
12/10/25 18:49	12/10/25	IMMX	Immix Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P.d	10	6.62	2	0	1,884	D
12/10/25 18:48	11/18/25	TENX	Tenax Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	6	P.dm	204	8.31	25	999%	25	D
12/10/25 17:05	12/9/25	ELTX	Elicio Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	2	4.41	0	95	1	D
12/10/25 16:56	12/9/25	SNSE	Sensei Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	6	S.dm	-580	10.24	-57		323	D
12/10/25 16:56	12/9/25	SNSE	Sensei Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	6	M.dm	580	10.24	57	21	323	D
12/10/25 16:32	11/6/25	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	4	6	S.d	-4,593	33.15	-139		348	D
12/10/25 16:29	12/8/25	MLTX	Moonlake Immunotherapeutics	E9	Health	Drug	Pharmaceutical Preparations	3	3	S.m	-6,086	14.71	-414		6,481	D
12/10/25 16:24	12/8/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	23	S.dm	-6,572	19.68	-334		466	D
12/9/25 19:40	12/5/25	XENE	Xenon Pharmaceuticals Inc.	A1	Health	Drug	Pharmaceutical Preparations	1	2	S.m	-1,147	45.33	-25		46	D
12/9/25 19:13	12/5/25	ALMS	Alumis Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	12	P.m	19,952	6.64	3,006	6	53,091	I
12/9/25 19:07	12/9/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	3	13	S.d	-4,160	18.74	-222		427	D
12/9/25 18:16	11/21/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	21	M.dm	695	2.81	247	42	830	D
12/9/25 18:16	11/24/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	21	S.dm	-695	2.81	-247		830	D
12/9/25 18:01	10/7/25	EBS	Emergent Biosolutions Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	5	S.d	-972	9.28	-105		452	D
12/9/25 16:36	11/13/25	MRVI	Maravai Lifesciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	P.m	1,880	3.32	567	26	2,732	I
12/8/25 20:05	12/8/25	ANVS	Annovis Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	8	P.d	2,816	2.27	1,239	44	4,024	D
12/8/25 17:15	11/21/25	DMAC	Diamedica Therapeutics Inc.	Z4	Health	Drug	Pharmaceutical Preparations	2	2	M.dm	7,658	7.14	1,073	14	8,914	D
12/8/25 16:30	12/4/25	XOMA	Xoma Royalty Corp	NV	Health	Drug	Pharmaceutical Preparations	1	1	P	2,505	25.05	100	99	201	D
12/8/25 16:30	12/4/25	CBIO	Crescent Biopharma, Inc.	E9	Health	Drug	Pharmaceutical Preparations	1	1	P.d	18,238	13.41	1,360	98	2,748	I
12/8/25 16:07	12/4/25	RNAC	Cartesian Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P.d	231	6.15	38	47	117	D
12/5/25 20:00	12/4/25	DNTH	Dianthus Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	2	4	M.dm	11,450	26.44	433		4	D
12/5/25 20:00	12/4/25	DNTH	Dianthus Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.dm	-11,450	26.44	-433		4	D
12/5/25 18:53	12/5/25	ENTA	Enanta Pharmaceuticals Inc		Health	Drug	Pharmaceutical Preparations	7	9	S	-183	14.22	-13		1,346	D
12/5/25 18:02	12/3/25	TBPH	Theravance Biopharma, Inc.	CA	Health	Drug	Pharmaceutical Preparations	2	4	S.d	-3,050	18.53	-165		338	D
12/5/25 16:21	12/3/25	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	1	7	M.d	1,053	26.65	39	115	74	D
12/5/25 16:21	12/3/25	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	1	7	S.d	-1,053	26.65	-39		74	D
12/5/25 16:16	12/3/25	VRTX	Vertex Pharmaceuticals Inc / Ma	MA	Health	Drug	Pharmaceutical Preparations	5	9	S.dm	-82,886	279.84	-296		141	D
12/5/25 16:11	12/5/25	DYN	Dyne Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-76	20.72	-4		451	D
12/4/25 19:39	12/2/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	6	M.dm	41,202	71.21	579	9	7,352	D
12/4/25 19:39	12/2/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	6	S.dm	-41,202	71.21	-579		7,352	D
12/4/25 19:00	12/2/25	QTTB	Q32 Bio Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-109	3.46	-32		139	D
12/4/25 17:15	12/2/25	SONN	Sonnet Biotherapeutics Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	0	0.00	250		0	D
12/4/25 16:50	12/2/25	ACRS	Aclaris Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	0	0.00	27		27	D
12/3/25 21:52	12/1/25	SYRE	Spyre Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S	-1,485	24.75	-60		702	D
12/3/25 20:00	12/1/25	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	6	M.d	894	19.16	47	122	85	D
12/3/25 20:00	12/1/25	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	6	S.d	-894	19.16	-47		85	D
12/3/25 19:01	12/1/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	12	30	S.dm	-38,472	64.80	-594		672	I
12/3/25 17:02	12/1/25	NUVB	Nuvation Bio Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	14	M.dm	8,069	4.54	1,778		42	D
12/3/25 17:02	12/1/25	NUVB	Nuvation Bio Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	14	S.dm	-8,069	4.54	-1,778		42	D
12/3/25 16:30	12/1/25	ANNX	Annexon, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	5	P.m	8,825	3.73	2,364	32	9,812	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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