Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	#o	#f	T	TVal	Price	Qty	oc	Own	H
11/18/25 21:45	11/14/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	11	S.dm	-3,345	8.44	-396		1,225	D
11/18/25 19:50	9/9/25	PAHC	Phibro Animal Health Corp	DE	Health	Drug	Pharmaceutical Preparations	1	10	S.dm	-7,870	42.58	-185		91	I
11/18/25 19:31	9/4/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	15	S.dm	-45,086	49.49	-911		7,266	I
11/18/25 19:04	11/15/25	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	M.d	250	2.52	99	5	2,194	D
11/18/25 19:04	11/17/25	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	S.d	-250	2.52	-99		2,194	D
11/18/25 18:39	11/14/25	NATR	Natures Sunshine Products Inc	UT	Health	Drug	Pharmaceutical Preparations	6	8	S.m	-241	6.66	-36		456	D
11/18/25 17:30	11/14/25	RNTX	Rein Therapeutics, Inc.		Health	Drug	Pharmaceutical Preparations	1	2	P.m	551	1.34	410	40	1,426	I
11/18/25 17:18	11/18/25	OPK	Opko Health, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	P	892	1.31	683	0	248,663	I
11/18/25 16:36	9/9/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	8	104	S.edm	-350,667	283.86	-1,235		725	D
11/18/25 16:36	11/14/25	TRDA	Entrada Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S.m	-4,873	8.43	-578		12,778	I
11/18/25 16:30	11/15/25	MCRB	Seres Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	M.d	45	3.73	12	53	35	D
11/18/25 16:30	11/15/25	MCRB	Seres Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	S.d	-45	3.73	-12		35	D
11/18/25 16:27	9/8/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	11	M.d	5,013	25.15	199	17	1,375	D
11/18/25 16:27	9/8/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	11	S.d	-5,013	25.15	-199		1,375	D
11/18/25 16:26	11/18/25	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	5	S	-21	1.10	-19		858	D
11/18/25 16:23	9/9/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	5	25	M.d	4,147	45.25	92	18	599	D
11/18/25 16:23	9/9/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	5	25	S.d	-4,147	45.25	-92		599	D
11/18/25 16:22	10/3/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	13	M.dm	5,414	20.44	265	109	508	D
11/18/25 16:22	10/3/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	13	S.dm	-5,414	20.44	-265		508	D
11/18/25 16:21	11/3/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	7	17	M.d	88,986	104.68	850		705	D
11/18/25 16:21	11/3/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	7	17	S.d	-88,986	104.68	-850		705	D
11/18/25 16:18	11/17/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	3	21	M.dm	7,768	16.23	479		438	D
11/18/25 16:18	11/17/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	3	21	S.dm	-7,768	16.23	-479		438	D
11/18/25 16:15	11/18/25	BIXT	Bioxytran, Inc	NV	Health	Drug	Pharmaceutical Preparations	1	1	P	126	0.6000	210	50	626	D
11/18/25 16:01	11/14/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	4	4	S	-5,897	24.23	-243		660	D
11/18/25 16:00	11/13/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	2	25	S.e	-2,011,014	701.49	-2,867		95,636	D
11/18/25 10:05	11/17/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	14	S.dm	-11,119	25.75	-432		2,278	D
11/18/25 07:44	11/14/25	ANVS	Annovis Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	P.d	2,233	2.04	1,095	39	3,920	D
11/18/25 07:29	11/13/25	BHVN	Biohaven Ltd.	D8	Health	Drug	Pharmaceutical Preparations	4	4	P	33,145	7.50	4,417	39	15,825	D
11/17/25 21:23	11/17/25	TTRX	Turn Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	P	200	4.75	42	3	1,485	D
11/17/25 19:56	11/3/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	20	S.dm	-6,518	18.19	-358		1,757	D
11/17/25 19:23	11/13/25	HOWL	Werewolf Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	15	S.m	-4,163	1.27	-3,268		17,018	I
11/17/25 19:03	11/13/25	TYRA	Tyra Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.m	-2,108	16.04	-131		297	D
11/17/25 18:01	9/19/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	7	10	S.m	-12,390	90.33	-137		989	D
11/17/25 17:58	9/11/25	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	4	6	S.dm	-1,213	5.04	-241		4,440	D
11/17/25 17:52	9/3/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	3	15	S.dm	-147,095	13.63	-10,791		67,807	D
11/17/25 16:59	11/13/25	ALMS	Alumis Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	1,450	5.25	276	6	4,768	I
11/17/25 16:48	11/13/25	MRVI	Maravai Lifesciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	P.m	1,512	3.24	467	23	2,467	I
11/17/25 16:42	11/13/25	FGEN	Fibrogen Inc	DE	Health	Drug	Pharmaceutical Preparations	1	1	P.m	34	9.12	4	17	25	D
11/17/25 16:38	11/14/25	SVRA	Savara Inc	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	9	1.46	6	5	121	D
11/17/25 16:16	11/13/25	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	1	5	M.d	762	21.86	35	84	77	D
11/17/25 16:16	11/13/25	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	1	5	S.d	-762	21.86	-35		77	D
11/17/25 16:12	11/13/25	VRTX	Vertex Pharmaceuticals Inc / Ma	MA	Health	Drug	Pharmaceutical Preparations	3	4	M.dm	39,169	265.47	148		45	D
11/17/25 16:12	11/13/25	VRTX	Vertex Pharmaceuticals Inc / Ma	MA	Health	Drug	Pharmaceutical Preparations	3	4	S.dm	-39,169	265.47	-148		45	D
11/17/25 16:05	11/14/25	AVTX	Avalo Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-244	12.47	-20	-100	0	D
11/17/25 16:05	11/14/25	AVTX	Avalo Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	M.d	244	12.47	20		0	D
11/17/25 09:02	11/13/25	CRVO	Cervomed Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	6	P.m	302	7.48	40	1	2,969	M
11/17/25 08:01	11/13/25	CATX	Perspective Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P	42	2.06	20	13	179	D
11/14/25 21:00	11/13/25	DNTH	Dianthus Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	2	4	M.dm	11,247	25.97	433		4	D
11/14/25 21:00	11/13/25	DNTH	Dianthus Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.dm	-11,247	25.97	-433		4	D
11/14/25 21:00	11/13/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	4	4	P	2,411	9.86	244	1	18,651	I
11/14/25 20:00	11/14/25	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	4	M.d	749	18.73	40	89	85	D
11/14/25 20:00	11/14/25	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	4	S.d	-749	18.73	-40		85	D
11/14/25 20:00	9/8/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	12	P	1,607	9.31	173	12	1,615	D
11/14/25 20:00	11/14/25	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-345	5.25	-66		1,487	D
11/14/25 18:43	11/12/25	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	8	M.dm	3,340	9.15	365	2	22,685	D
11/14/25 18:43	11/12/25	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	8	S.dm	-3,340	9.15	-365		22,685	D
11/14/25 17:35	11/12/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	6	12	M.dm	29,311	307.29	95	0	56,536	D
11/14/25 17:35	11/12/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	6	12	S.dm	-29,311	307.29	-95	0	56,536	D
11/14/25 17:13	8/27/25	AMRX	Amneal Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	3	6	S.dm	-6,496	7.46	-871		524	D
11/14/25 17:12	11/13/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	M.d	22,263	342.27	65	95	134	D
11/14/25 17:12	11/13/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	S.d	-22,263	342.27	-65		134	D
11/14/25 17:00	11/12/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	11	S.dm	-6,927	8.98	-771		1,937	D
11/14/25 16:35	10/14/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	6	28	M.dm	28,524	22.65	1,259		409	D
11/14/25 16:35	10/14/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	6	28	S.dm	-28,524	22.65	-1,259		409	D
11/14/25 16:30	11/13/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	6	S.m	-410	5.22	-79		2,066	D
11/14/25 16:13	11/12/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	6	10	M.dm	36,597	322.94	113	139	195	D
11/14/25 16:13	11/12/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	6	10	S.dm	-36,597	322.94	-113		195	D
11/14/25 16:10	11/6/25	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	3	4	S.d	-3,965	33.84	-117		262	D
11/14/25 16:04	10/30/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	17	M.d	907	27.33	33	41	114	D
11/14/25 16:04	10/30/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	17	S.d	-907	27.33	-33		114	D
11/14/25 16:02	11/11/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	4	20	S.dm	-1,968	4.21	-468		6,727	D
11/14/25 15:07	11/12/25	CVRX	Cvrx, Inc.	NJ	Health	Drug	Pharmaceutical Preparations	1	2	S.m	-546	10.21	-54		4,051	I
11/14/25 10:45	9/9/25	PRGO	Perrigo Co Plc	L2	Health	Drug	Pharmaceutical Preparations	5	5	M.d	365	19.27	19	19	121	D
11/14/25 08:17	11/13/25	ZOMDF	Zomedica Corp.	A0	Health	Drug	Pharmaceutical Preparations	1	4	P	47	0.0891	528	10	5,784	D
11/14/25 06:00	11/11/25	TBPH	Theravance Biopharma, Inc.	CA	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-1,878	18.05	-104		60	D
11/13/25 20:57	11/11/25	VERA	Vera Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-475	19.01	-25		58	D
11/13/25 20:57	11/13/25	VERA	Vera Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	M.d	475	19.01	25	76	58	D
11/13/25 20:22	10/15/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	7	S.dm	-77,001	77.01	-1,000		4,089	I
11/13/25 20:13	11/10/25	SEPN	Septerna, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-63	18.06	-4		93	D
11/13/25 19:01	11/11/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	13	M.dm	65,692	28.11	2,337	19	14,617	D
11/13/25 19:01	11/11/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	13	S.dm	-65,692	28.11	-2,337		14,617	D
11/13/25 18:06	11/12/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	5	M.d	3,808	9.27	411		47	D
11/13/25 18:06	11/12/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	5	S.d	-3,808	9.27	-411		47	D
11/13/25 16:41	11/11/25	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-97	4.86	-20		54	D
11/13/25 16:28	9/6/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	18	M.d	471	4.29	110	19	686	D
11/13/25 16:28	9/8/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	18	S.d	-471	4.29	-110		686	D
11/13/25 16:13	11/10/25	PCRX	Pacira Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-330	22.92	-14		65	D
11/13/25 16:05	11/12/25	OGN	Organon & Co.		Health	Drug	Pharmaceutical Preparations	4	5	P.d	502	6.20	81	134	141	I
11/12/25 20:44	11/7/25	SPRO	Spero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-112	2.30	-49		2,312	D
11/12/25 20:36	11/10/25	LYEL	Lyell Immunopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	8	S	-132	10.95	-12		133	D
11/12/25 18:00	11/10/25	ASRT	Assertio Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-7	0.7597	-9		99	D
11/12/25 18:00	9/15/25	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-795	22.66	-35		73	D
11/12/25 17:34	10/17/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	17	S.dm	-1,848	19.05	-97		2,174	I
11/12/25 16:45	11/7/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	4	8	M.d	4,906	149.11	33	19	210	D
11/12/25 16:45	11/7/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	4	8	S.d	-4,906	149.11	-33		210	D
11/12/25 16:33	11/10/25	APVO	Aptevo Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	20	1.49	14	999%	14	D
11/12/25 16:30	8/28/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	11	34	S.dm	-28,023	25.44	-1,101		10,500	I
11/12/25 16:30	11/7/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	12	M.dm	9,214	65.04	142		29	D
11/12/25 16:30	11/7/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	12	S.dm	-9,214	65.04	-142		29	D
11/12/25 16:26	11/7/25	EVMN	Evommune, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	P.d	70,000	16.00	4,375	70	10,644	I
11/12/25 16:13	10/7/25	EBS	Emergent Biosolutions Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-579	10.17	-57		353	D
11/12/25 16:07	11/11/25	ALT	Altimmune, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	0	0.00	19	433	23	D
11/12/25 16:04	9/29/25	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	9	S.dm	-4,082	13.09	-312		1,795	D
11/12/25 16:01	11/10/25	MRK	Merck & Co., Inc.	NJ	Health	Drug	Pharmaceutical Preparations	2	2	S	-1,336	85.13	-16		25	D
11/12/25 12:38	11/10/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	1	16	M.dm	478	3.06	156		0	D
11/12/25 12:38	11/10/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	1	16	S.dm	-478	3.06	-156	-100	0	D
11/12/25 06:05	11/7/25	GLSI	Greenwich Lifesciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	P	111	8.58	13	0	5,584	D
11/10/25 21:51	11/7/25	BNTC	Benitec Biopharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	20,000	13.50	1,481	438	1,820	I
11/10/25 19:14	9/16/25	LFVN	Lifevantage Corp		Health	Drug	Pharmaceutical Preparations	7	8	P.d	304	0.7630	398	34	1,568	D
11/10/25 18:30	11/3/25	MURA	Mural Oncology Plc	L2	Health	Drug	Pharmaceutical Preparations	2	2	S	-25	2.09	-12		184	D
11/10/25 16:54	11/6/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	4	8	M.dm	14,412	23.49	614	194	930	D
11/10/25 16:54	11/6/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	4	8	S.dm	-14,412	23.49	-614		930	D
11/10/25 16:37	11/7/25	REGN	Regeneron Pharmaceuticals, Inc.	NY	Health	Drug	Pharmaceutical Preparations	3	4	S.dm	-28,772	562.59	-51		64	D
11/10/25 16:05	11/6/25	CTMX	Cytomx Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-462	4.54	-102		1,081	D
11/7/25 17:13	11/6/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	14	66	S.dm	-107,252	55.96	-1,916		850	D
11/7/25 17:10	11/5/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	7	28	M.dm	22,437	53.79	417	16	2,999	D
11/7/25 17:10	11/5/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	7	28	S.dm	-22,437	53.79	-417		2,999	D
11/7/25 16:58	11/6/25	EVOK	Evoke Pharma Inc	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-96	10.65	-9		154	I
11/7/25 16:20	11/7/25	ARVN	Arvinas, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-229	7.58	-30		108	D
11/7/25 16:01	11/5/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	7	9	S	-1,005	11.47	-88		4,792	D
11/6/25 20:25	11/4/25	MBRX	Moleculin Biotech, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	M.d	2	0.0395	63	6	1,085	D
11/6/25 18:12	11/4/25	ANTX	An2 Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-4	1.14	-4		243	D
11/6/25 16:05	11/4/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	6	12	M.dm	11,052	25.48	434	109	830	D
11/6/25 16:05	11/4/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	6	12	S.dm	-11,052	25.48	-434		830	D
11/6/25 12:21	11/3/25	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	5	6	S.m	-121	9.32	-13		704	D
11/6/25 08:01	11/5/25	NVCT	Nuvectis Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	P.m	1,125	6.12	184	3	6,975	D
11/6/25 07:30	11/5/25	RLMD	Relmada Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	4	5	P.m	2,375	1.88	1,264	74	2,967	D
11/6/25 07:00	9/2/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	19	M.dm	9,288	25.76	361	18	2,392	D
11/6/25 07:00	9/2/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	19	S.dm	-9,288	25.76	-361		2,392	D
11/5/25 21:15	11/3/25	SYRE	Spyre Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-1,349	21.27	-63		800	D
11/5/25 19:01	9/2/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	16	S.dm	-58,202	74.60	-780		7,945	D
11/5/25 18:17	10/1/25	TERN	Terns Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S.d	-675	13.51	-50		52	D
11/5/25 18:00	11/5/25	BGMS	Bio Green Med Solution, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	18	S.dm	-5,100	3.12	-1,633		1,679	D
11/5/25 17:00	9/2/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	12	M.d	3,360	26.57	126	10	1,417	D
11/5/25 17:00	9/2/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	12	S.d	-3,360	26.57	-126		1,417	D
11/5/25 16:30	11/3/25	PHAT	Phathom Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S.d	-13	0.1391	-91		97	D
11/5/25 16:05	11/4/25	FOLD	Amicus Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-244	9.51	-26		323	D
11/5/25 09:57	11/3/25	MTSR	Metsera, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S	-21	46.56	0	0	4,325	I
11/4/25 17:18	10/2/25	BMY	Bristol Myers Squibb Co	DE	Health	Drug	Pharmaceutical Preparations	6	6	M.d	2,650	34.28	77	28	349	D
11/4/25 16:13	10/31/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	3	6	M.d	1,036	1.68	616	163	994	D
11/4/25 16:13	11/3/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	3	6	S.d	-1,036	1.68	-616		994	D
11/4/25 12:35	10/31/25	HRTX	Heron Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	3	6	M.d	0	0.00	80	10	869	D
11/3/25 20:00	10/31/25	BTAI	Bioxcel Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	7	M.dm	0	0.00	6	1	541	D
11/3/25 19:14	11/3/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	S.d	-238	3.85	-62		182	D
11/3/25 17:25	5/14/25	ORGO	Organogenesis Holdings Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	P.m	1,177	3.09	381	3	12,249	I
11/3/25 17:25	6/9/25	ORGO	Organogenesis Holdings Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.m	-1,177	3.09	-381		12,249	I
11/3/25 16:37	11/3/25	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	1	4	M.d	751	26.81	28	61	74	D
11/3/25 16:37	11/3/25	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	1	4	S.d	-751	26.81	-28		74	D
10/31/25 16:31	8/29/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	32	M.dm	30,816	56.95	541	36	2,060	D
10/31/25 16:15	10/30/25	ANNX	Annexon, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	3	P	34	2.77	12	36	46	D
10/31/25 15:30	10/29/25	SYBX	Synlogic, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	0	1.81	0		13	D
10/31/25 09:13	10/30/25	ANIX	Anixa Biosciences Inc	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	584	2.92	200	49	610	D
10/30/25 16:31	10/28/25	MPLT	Maplight Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P.d	108,700	17.00	6,394	38	23,384	I
10/29/25 16:24	10/27/25	NUVB	Nuvation Bio Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	M.d	676	3.38	200		0	D
10/29/25 16:24	10/27/25	NUVB	Nuvation Bio Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-676	3.38	-200	-100	0	D
10/29/25 16:11	10/27/25	PMVP	Pmv Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	M.d	2,722	1.58	1,721	32	7,102	D
10/28/25 21:05	9/4/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	21	M.dm	46,664	29.58	1,578	55	4,444	D
10/28/25 21:05	9/4/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	21	S.dm	-46,664	29.58	-1,578		4,444	D
10/28/25 19:51	10/28/25	VKTX	Viking Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	S.d	-3,932	35.31	-111		3,005	D
10/28/25 17:00	10/24/25	CVKD	Cadrenal Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	12	S.m	-641	14.03	-46		445	D
10/28/25 16:10	10/25/25	MRSN	Mersana Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	M.d	15	1.72	9	259	12	D
10/28/25 16:10	10/27/25	MRSN	Mersana Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.d	-15	1.72	-9		12	D
10/28/25 08:03	9/26/25	MBX	Mbx Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	P.d	13,132	14.76	890	16	6,372	I
10/27/25 19:24	10/20/25	RANI	Rani Therapeutics Holdings, Inc.	CA	Health	Drug	Pharmaceutical Preparations	2	2	S.dm	-16,972	2.12	-8,006		27,197	I
10/27/25 16:30	10/23/25	VRDN	Viridian Therapeutics, Inc.De	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	10,000	22.00	455	13	3,914	I
10/27/25 16:23	10/24/25	CRBP	Corbus Pharmaceuticals Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	M.dm	892	10.70	83	62	218	D
10/27/25 16:23	10/24/25	CRBP	Corbus Pharmaceuticals Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	S.dm	-892	10.70	-83		218	D
10/27/25 16:15	10/23/25	TNGX	Tango Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	6	S.m	-26,351	7.59	-3,473		15,759	D
10/24/25 20:00	10/22/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	6	S.m	-1,305	1.26	-1,034		671	D
10/24/25 19:19	6/6/25	BOLT	Bolt Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P	1	5.50	0	0	66	D
10/24/25 16:56	10/22/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	25	M.d	10,129	29.21	347	99	695	D
10/24/25 16:56	10/22/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	25	S.d	-10,129	29.21	-347		695	D
10/24/25 16:30	10/23/25	ALZN	Alzamend Neuro, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	8	S.dm	-1,584	2.40	-661		124	D
10/23/25 21:06	10/21/25	SMMT	Summit Therapeutics Inc.		Health	Drug	Pharmaceutical Preparations	3	5	P.m	22,969	18.18	1,264	0	1,244,269	I
10/23/25 19:49	10/21/25	NEUP	Neuphoria Therapeutics Inc.	C3	Health	Drug	Pharmaceutical Preparations	1	1	P	3,283	5.14	639	271	875	I
10/23/25 17:10	10/22/25	ETNB	89Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	256	3.17	81	31	339	D
10/22/25 16:15	10/20/25	SPRB	Spruce Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	M.d	19	2.42	8	90	17	D
10/20/25 20:00	9/12/25	BYSI	Beyondspring Inc.		Health	Drug	Pharmaceutical Preparations	1	14	S.m	-697	1.74	-401		4,423	I
10/20/25 19:13	10/17/25	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	4	7	M.d	60,109	143.27	420	221	609	D
10/20/25 19:13	10/17/25	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	4	7	S.d	-60,109	143.27	-420		609	D
10/20/25 18:58	10/16/25	LVTX	Lava Therapeutics Nv	P7	Health	Drug	Pharmaceutical Preparations	2	5	S.m	-11,712	1.45	-8,061		8,198	D
10/20/25 16:12	9/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	S	-120	2.79	-43		2,387	D
10/20/25 16:11	10/9/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	18	M.dm	4,774	11.43	418	151	693	D
10/20/25 16:11	10/9/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	18	S.dm	-4,774	11.43	-418		693	D
10/20/25 09:11	10/17/25	GOVX	Geovax Labs, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	5	0.5498	10	88	21	D
10/17/25 17:53	10/15/25	KROS	Keros Therapeutics, Inc.		Health	Drug	Pharmaceutical Preparations	2	2	S	-180,635	17.75	-10,177	-100	11	I
10/17/25 16:28	10/16/25	SDGR	Schrodinger, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-29	21.07	-1		25	D
10/17/25 16:10	9/24/25	PRAX	Praxis Precision Medicines, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	M.d	33,682	103.27	326	8	4,439	D
10/17/25 16:05	10/15/25	GBIO	Generation Bio Co.	DE	Health	Drug	Pharmaceutical Preparations	5	5	M.d	0	0.00	1	1	209	D
10/17/25 14:01	10/15/25	AQST	Aquestive Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	10	M.d	1,867	5.31	352	23	1,871	D
10/17/25 14:01	10/15/25	AQST	Aquestive Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	10	S.d	-1,867	5.31	-352		1,871	D
10/16/25 18:14	10/15/25	AARD	Aardvark Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	M.dm	389	6.99	56	2	3,125	D
10/16/25 16:01	10/14/25	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-149	3.82	-39		107	D
10/15/25 17:15	10/14/25	QNRX	Quoin Pharmaceuticals, Ltd.	L3	Health	Drug	Pharmaceutical Preparations	1	1	P.d	129	8.49	15	999%	15	D
10/14/25 17:16	10/9/25	ZBIO	Zenas Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	6	P.m	18,628	18.97	982	7	15,283	I
10/14/25 16:01	10/10/25	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	1	4	M.d	1,557	48.66	32		9	D
10/14/25 16:01	10/10/25	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	1	4	S.d	-1,557	48.66	-32		9	D
10/14/25 12:15	9/12/25	RARE	Ultragenyx Pharmaceutical Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	S	-331	31.42	-11		222	D
10/10/25 20:06	10/8/25	ACET	Adicet Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	5,000	1.00	5,000	207	7,421	I

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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