Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	#o	#f	T	TVal	Price	Qty	oc	Own	H
12/2/25 19:00	12/1/25	GNLX	Genelux Corp	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-50	5.00	-10		493	D
12/2/25 18:45	11/28/25	PHAT	Phathom Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	M.d	13	0.0699	181		138	D
12/2/25 17:14	9/11/25	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	3	5	S.dm	-682	4.06	-168		4,215	D
12/2/25 17:14	9/9/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	7	30	M.d	6,996	42.94	163	31	683	D
12/2/25 17:14	9/9/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	7	30	S.d	-6,996	42.94	-163		683	D
12/2/25 16:43	11/28/25	PBH	Prestige Consumer Healthcare Inc.		Health	Drug	Pharmaceutical Preparations	1	1	S.m	-60	60.00	-1		42	D
12/2/25 16:34	11/28/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	9	33	M.d	6,950	18.41	377	9	4,503	D
12/2/25 16:34	12/1/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	9	33	S.d	-6,950	18.41	-377		4,503	D
12/2/25 16:32	9/9/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	8	118	S.edm	-415,934	289.17	-1,438		725	D
12/2/25 16:30	11/24/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	37	S.dm	-108,476	78.83	-1,376		19,309	I
12/2/25 16:15	9/9/25	PAHC	Phibro Animal Health Corp	DE	Health	Drug	Pharmaceutical Preparations	1	13	S.dm	-8,855	42.64	-208		91	I
12/2/25 16:15	11/28/25	BMEA	Biomea Fusion, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P.m	55	1.09	50	2	2,543	D
12/2/25 16:04	11/18/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	11	M.d	10,509	33.36	315	81	702	D
12/2/25 16:02	11/28/25	RNAC	Cartesian Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	25	3.30	8	14	63	D
12/1/25 19:02	11/26/25	TBPH	Theravance Biopharma, Inc.	CA	Health	Drug	Pharmaceutical Preparations	1	3	S.d	-2,468	18.48	-134		60	D
12/1/25 18:14	11/18/25	JAZZ	Jazz Pharmaceuticals Plc	L2	Health	Drug	Pharmaceutical Preparations	5	10	S.dm	-32,315	154.95	-209		518	D
12/1/25 18:14	11/18/25	JAZZ	Jazz Pharmaceuticals Plc	L2	Health	Drug	Pharmaceutical Preparations	5	10	M.dm	32,315	154.95	209	67	518	D
12/1/25 18:13	11/26/25	HOWL	Werewolf Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	24	S.m	-5,389	1.18	-4,583		17,018	I
12/1/25 18:10	10/1/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S	-1,643	37.56	-44		301	D
12/1/25 18:09	11/26/25	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	13	M.dm	5,294	14.29	371	26	1,795	D
12/1/25 18:09	11/26/25	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	13	S.dm	-5,294	14.29	-371		1,795	D
12/1/25 18:09	11/26/25	ALMS	Alumis Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	10	P.m	16,079	6.29	2,557	5	52,643	I
12/1/25 17:41	12/1/25	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	1	5	S.d	-868	27.12	-32		74	D
12/1/25 17:17	11/26/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	8	12	M.d	333	9.77	34	20	205	D
12/1/25 16:57	11/12/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	5	14	M.dm	32,103	307.18	105	0	56,464	D
12/1/25 16:57	11/12/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	5	14	S.dm	-32,103	307.18	-105	0	56,464	D
12/1/25 16:40	11/26/25	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	6	11	S.dm	-412	8.96	-46		713	D
12/1/25 16:37	11/26/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	6	24	M.dm	27,759	23.99	1,157		406	D
12/1/25 16:37	11/26/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	6	24	S.dm	-27,759	23.99	-1,157		406	D
12/1/25 16:17	9/8/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	13	M.d	5,173	24.71	209	18	1,375	D
12/1/25 16:17	9/8/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	13	S.d	-5,173	24.71	-209		1,375	D
12/1/25 16:15	11/26/25	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	3	5	P.d	23,667	150.14	158	479	191	D
12/1/25 16:10	11/26/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	6	12	M.dm	41,995	311.45	135	212	198	D
12/1/25 16:07	11/26/25	CVRX	Cvrx, Inc.	NJ	Health	Drug	Pharmaceutical Preparations	1	4	S.m	-637	10.18	-63		4,051	I
12/1/25 16:02	11/26/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	4	7	S.d	-7,898	20.51	-385		695	I
12/1/25 09:07	11/28/25	KTTA	Pasithea Therapeutics Corp.	DE	Health	Drug	Pharmaceutical Preparations	3	3	P	150	0.7500	200	184	309	D
12/1/25 06:20	11/28/25	MAIA	Maia Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	8	P.dm	218	1.08	202	8	2,865	D
11/28/25 17:51	11/25/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	13	49	M.dm	64,551	62.18	1,038		798	I
11/28/25 17:51	11/25/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	13	49	S.dm	-64,551	62.18	-1,038		798	I
11/28/25 17:38	9/8/25	BHC	Bausch Health Companies Inc.	NJ	Health	Drug	Pharmaceutical Preparations	2	2	S	-15,723	6.26	-2,513		73,755	D
11/28/25 17:00	11/26/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	11	18	M.dm	3,171	8.77	362	6	6,806	D
11/28/25 17:00	11/26/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	11	18	S.dm	-3,171	8.77	-362		6,806	D
11/28/25 16:05	11/25/25	MRUS	Merus N.V.	P7	Health	Drug	Pharmaceutical Preparations	1	2	M.d	796	47.96	17		11	D
11/28/25 16:05	11/25/25	MRUS	Merus N.V.	P7	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-796	47.96	-17		11	D
11/28/25 09:00	11/26/25	COCP	Cocrystal Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	P	23	0.9495	24	1	1,731	I
11/28/25 06:05	11/25/25	GLSI	Greenwich Lifesciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	3	P	149	8.52	18	0	5,588	D
11/28/25 06:03	9/8/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	19	M.dm	9,362	18.70	501	25	2,510	D
11/28/25 06:03	9/8/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	19	S.dm	-9,362	18.70	-501		2,510	D
11/26/25 21:30	11/24/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	13	M.dm	3,702	8.25	449	58	1,225	D
11/26/25 21:30	11/24/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	13	S.dm	-3,702	8.25	-449		1,225	D
11/26/25 21:18	11/24/25	FOLD	Amicus Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	M.dm	3,479	8.75	398	20	2,422	D
11/26/25 21:18	11/24/25	FOLD	Amicus Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	S.dm	-3,479	8.75	-398		2,422	D
11/26/25 18:50	11/21/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	19	M.dm	639	2.75	232	42	782	D
11/26/25 18:50	11/24/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	19	S.dm	-639	2.75	-232		782	D
11/26/25 18:45	9/4/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	18	M.dm	59,528	33.53	1,775	18	11,566	D
11/26/25 18:45	9/4/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	18	S.dm	-59,528	33.53	-1,775		11,566	D
11/26/25 18:24	11/24/25	ORGO	Organogenesis Holdings Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	3	S.m	-2,769	4.06	-681		12,249	D
11/26/25 17:55	11/25/25	NUVB	Nuvation Bio Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	12	M.dm	6,456	4.37	1,478		42	D
11/26/25 17:55	11/25/25	NUVB	Nuvation Bio Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	12	S.dm	-6,456	4.37	-1,478		42	D
11/26/25 17:22	11/25/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	6	20	S.dm	-16,022	56.36	-284		2,922	D
11/26/25 17:21	11/24/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	1	20	M.d	194	2.24	87		6	D
11/26/25 17:21	11/24/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	1	20	S.d	-194	2.24	-87		6	D
11/26/25 17:01	11/19/25	RPRX	Royalty Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	2	3	S	-10,610	38.64	-275		1,829	M
11/26/25 16:31	11/3/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	6	12	M.d	50,334	122.84	410	230	588	D
11/26/25 16:31	11/3/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	6	12	S.d	-50,334	122.84	-410		588	D
11/26/25 16:30	11/25/25	ADTX	Aditxt, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	0	3.00	0	-100	0	D
11/26/25 16:06	10/3/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	10	M.d	4,746	23.05	206	81	460	D
11/26/25 16:06	10/3/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	10	S.d	-4,746	23.05	-206		460	D
11/26/25 16:05	11/24/25	SLGL	Sol-Gel Technologies Ltd.	L3	Health	Drug	Pharmaceutical Preparations	1	2	P.m	245	36.41	7	2	374	I
11/26/25 16:02	11/24/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	6	8	S	-973	11.45	-85		4,441	D
11/26/25 16:00	11/13/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	2	31	S.e	-2,010,362	567.74	-3,541		95,635	D
11/26/25 14:58	11/26/25	ABCL	Abcellera Biologics Inc.	A1	Health	Drug	Pharmaceutical Preparations	1	1	P	178	3.57	50	28	226	D
11/25/25 21:00	11/24/25	TTRX	Turn Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	7	P.m	300	4.00	75	5	1,518	D
11/25/25 20:30	11/25/25	NKTR	Nektar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	3	6	S.dm	-1,017	41.99	-24		97	D
11/25/25 19:38	11/13/25	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	2	6	M.d	929	21.76	43	62	111	D
11/25/25 19:38	11/13/25	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	2	6	S.d	-929	21.76	-43		111	D
11/25/25 19:00	11/25/25	VRCA	Verrica Pharmaceuticals Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	5	P.d	17,973	4.24	4,236	108	8,148	D
11/25/25 18:59	11/24/25	ANVS	Annovis Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	7	P.d	2,622	2.20	1,194	43	3,979	D
11/25/25 18:42	11/24/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	26	M.dm	6,620	11.43	579	507	693	D
11/25/25 18:42	11/24/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	26	S.dm	-6,620	11.43	-579		693	D
11/25/25 18:27	11/3/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	9	23	S.dm	-9,420	20.22	-466		1,799	D
11/25/25 18:08	11/25/25	EQ	Equillium, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-8	0.9504	-8		127	D
11/25/25 18:00	9/16/25	OLMA	Olema Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S.dm	-219	3.60	-61		1,247	M
11/25/25 17:31	11/24/25	TGTX	Tg Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-835	32.30	-26		318	D
11/25/25 17:00	11/21/25	TYRA	Tyra Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S.m	-9,139	18.14	-504		4,130	I
11/25/25 16:44	11/21/25	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	6	S	-453	5.54	-82		2,816	D
11/25/25 16:30	11/21/25	DMAC	Diamedica Therapeutics Inc.	Z4	Health	Drug	Pharmaceutical Preparations	1	1	M.d	26	2.20	12	16	88	D
11/25/25 16:17	11/25/25	ABT	Abbott Laboratories	IL	Health	Drug	Pharmaceutical Preparations	1	1	S	-203	128.02	-2		30	D
11/25/25 16:11	11/21/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	3	6	S.d	-595	22.48	-26		132	D
11/25/25 16:10	11/21/25	HRMY	Harmony Biosciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-120	2.48	-48		21	D
11/25/25 16:06	11/24/25	SAVA	Cassava Sciences Inc	DE	Health	Drug	Pharmaceutical Preparations	3	6	P.m	1,232	2.51	491	105	960	D
11/25/25 16:05	11/21/25	VERA	Vera Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S.d	-583	20.19	-29		107	D
11/24/25 21:10	11/21/25	NTHI	Neonc Technologies Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P.m	192	6.17	31	0	10,628	D
11/24/25 18:46	9/4/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	17	S.dm	-50,595	51.40	-984		7,228	I
11/24/25 18:16	9/25/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	24	M.d	20,012	31.33	639	37	2,358	D
11/24/25 18:06	11/3/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	10	S.d	-950	6.93	-137		182	D
11/24/25 18:00	11/21/25	RNXT	Renovorx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P.m	18	0.8000	22	3	756	D
11/24/25 17:08	11/20/25	SLRX	Salarius Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P	20	0.7896	25	999%	25	I
11/24/25 17:07	11/20/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	15	S.dm	-109,055	32.45	-3,361		22,520	I
11/24/25 16:42	11/20/25	GRTX	Galera Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-1	0.0201	-70		195	D
11/24/25 16:30	11/21/25	TRDA	Entrada Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	5	S.m	-5,223	8.48	-616		12,914	D
11/24/25 16:15	11/20/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	10	M.dm	6,849	64.35	106		29	D
11/24/25 16:15	11/20/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	10	S.dm	-6,849	64.35	-106		29	D
11/24/25 16:07	11/7/25	REGN	Regeneron Pharmaceuticals, Inc.	NY	Health	Drug	Pharmaceutical Preparations	5	7	S.dm	-37,654	561.05	-67		107	D
11/24/25 12:54	11/21/25	PHIO	Phio Pharmaceuticals Corp.	DE	Health	Drug	Pharmaceutical Preparations	1	2	P	12	1.21	10	4	281	D
11/21/25 21:52	10/30/25	ANNX	Annexon, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	P.m	8,681	3.72	2,331	31	9,775	D
11/21/25 21:41	9/24/25	PRAX	Praxis Precision Medicines, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	6	M.d	43,831	108.60	404	10	4,470	D
11/21/25 20:24	9/3/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	6	16	S.dm	-224,452	15.49	-14,491		121,801	D
11/21/25 19:54	11/19/25	PGEN	Precigen, Inc.	VA	Health	Drug	Pharmaceutical Preparations	6	9	S.dm	-37,858	1.38	-27,370		130,226	I
11/21/25 18:35	11/20/25	SILO	Silo Pharma, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	2	P.m	6	0.3987	14	7	212	D
11/21/25 18:13	11/20/25	SGMT	Sagimet Biosciences Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-290	7.69	-38		81	D
11/21/25 17:39	11/21/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	6	S.d	-20,298	341.80	-59		136	D
11/21/25 17:28	11/17/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	15	S.dm	-2,047	20.16	-102		2,161	I
11/21/25 17:07	11/21/25	OPK	Opko Health, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	5	P	3,192	1.32	2,423	1	250,403	I
11/21/25 17:00	10/15/25	GBIO	Generation Bio Co.	DE	Health	Drug	Pharmaceutical Preparations	5	6	M.d	0	0.00	2	1	209	D
11/21/25 16:59	9/16/25	LFVN	Lifevantage Corp		Health	Drug	Pharmaceutical Preparations	2	4	P	385	7.21	53	29	237	D
11/21/25 16:25	11/19/25	PVLA	Palvella Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	2	M.d	406	47.17	9		0	D
11/21/25 16:25	11/19/25	PVLA	Palvella Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-406	47.17	-9	-100	0	D
11/21/25 16:15	11/19/25	FULC	Fulcrum Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-165	11.03	-15		485	D
11/21/25 08:45	11/19/25	SLS	Sellas Life Sciences Group, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	101	1.59	63	155	104	D
11/20/25 18:38	11/18/25	TENX	Tenax Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	P.dm	108	7.41	15		13	D
11/20/25 16:05	11/18/25	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	5	S	-149	3.68	-40		1,934	D
11/20/25 16:00	11/19/25	LITS	Lite Strategy, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	23	1.88	12	68	30	D
11/20/25 07:00	11/18/25	ITRM	Iterum Therapeutics Plc	L2	Health	Drug	Pharmaceutical Preparations	1	1	P	2	0.3652	6	3	241	D
11/19/25 18:28	11/12/25	NATR	Natures Sunshine Products Inc	UT	Health	Drug	Pharmaceutical Preparations	6	9	S	-363	8.99	-40		456	D
11/19/25 18:00	11/17/25	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	3	6	M.d	1,094	14.46	76	999%	82	D
11/19/25 18:00	11/18/25	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	3	6	S.d	-1,094	14.46	-76		82	D
11/19/25 16:32	11/17/25	PCRX	Pacira Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-426	23.17	-18		244	D
11/19/25 16:21	11/17/25	AMRX	Amneal Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	2	3	S.d	-2,520	8.03	-314		437	D
11/19/25 16:06	11/17/25	VRTX	Vertex Pharmaceuticals Inc / Ma	MA	Health	Drug	Pharmaceutical Preparations	3	4	S.dm	-40,152	268.08	-150		57	D
11/19/25 16:06	11/17/25	CYPH	Cypherpunk Technologies Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-5,069	3.14	-1,614		132	I
11/19/25 16:05	11/17/25	IRWD	Ironwood Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-20	3.32	-6		235	D
11/19/25 16:01	11/11/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	4	24	S.dm	-2,757	4.12	-669		6,727	D
11/19/25 16:01	11/17/25	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.d	-1,550	50.47	-31		86	D
11/19/25 07:46	11/17/25	CRVO	Cervomed Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	10	P.m	738	8.02	92	3	3,021	D
11/18/25 19:04	11/15/25	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	M.d	250	2.52	99	5	2,194	D
11/18/25 19:04	11/17/25	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	S.d	-250	2.52	-99		2,194	D
11/18/25 17:30	11/14/25	RNTX	Rein Therapeutics, Inc.		Health	Drug	Pharmaceutical Preparations	1	2	P.m	551	1.34	410	40	1,426	I
11/18/25 16:30	11/15/25	MCRB	Seres Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	M.d	45	3.73	12	53	35	D
11/18/25 16:30	11/15/25	MCRB	Seres Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	S.d	-45	3.73	-12		35	D
11/18/25 16:26	11/18/25	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	5	S	-21	1.10	-19		858	D
11/18/25 16:18	11/17/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	3	21	M.dm	7,768	16.23	479		438	D
11/18/25 16:18	11/17/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	3	21	S.dm	-7,768	16.23	-479		438	D
11/18/25 16:15	11/18/25	BIXT	Bioxytran, Inc	NV	Health	Drug	Pharmaceutical Preparations	1	1	P	126	0.6000	210	50	626	D
11/18/25 10:05	11/17/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	12	S.d	-4,750	23.04	-206		632	D
11/18/25 07:29	11/13/25	BHVN	Biohaven Ltd.	D8	Health	Drug	Pharmaceutical Preparations	4	4	P	33,145	7.50	4,417	39	15,825	D
11/17/25 18:01	9/19/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	4	6	S.m	-2,272	88.81	-26		427	D
11/17/25 16:48	11/13/25	MRVI	Maravai Lifesciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	P.m	1,512	3.24	467	23	2,467	I
11/17/25 16:42	11/13/25	FGEN	Fibrogen Inc	DE	Health	Drug	Pharmaceutical Preparations	1	1	P.m	34	9.12	4	17	25	D
11/17/25 16:38	11/14/25	SVRA	Savara Inc	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	9	1.46	6	5	121	D
11/17/25 16:05	11/14/25	AVTX	Avalo Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-244	12.47	-20	-100	0	D
11/17/25 16:05	11/14/25	AVTX	Avalo Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	M.d	244	12.47	20		0	D
11/17/25 08:01	11/13/25	CATX	Perspective Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P	42	2.06	20	13	179	D
11/14/25 21:00	11/13/25	DNTH	Dianthus Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	2	4	M.dm	11,247	25.97	433		4	D
11/14/25 21:00	11/13/25	DNTH	Dianthus Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.dm	-11,247	25.97	-433		4	D
11/14/25 21:00	11/13/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	2	2	P	116	6.78	17	0	18,245	I
11/14/25 20:00	11/14/25	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	4	M.d	749	18.73	40	89	85	D
11/14/25 20:00	11/14/25	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	4	S.d	-749	18.73	-40		85	D
11/14/25 20:00	9/8/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	12	P	1,607	9.31	173	12	1,615	D
11/14/25 20:00	11/14/25	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-345	5.25	-66		1,487	D
11/14/25 18:43	11/12/25	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	M.d	1,705	7.10	240		11	D
11/14/25 18:43	11/12/25	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.d	-1,705	7.10	-240		11	D
11/14/25 16:30	11/13/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	6	S.m	-410	5.22	-79		2,066	D
11/14/25 16:10	11/6/25	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	2	3	S.d	-3,294	33.04	-100		191	D
11/14/25 16:04	10/30/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	15	M.d	895	27.31	33	40	114	D
11/14/25 16:04	10/30/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	15	S.d	-895	27.31	-33		114	D
11/14/25 10:45	9/9/25	PRGO	Perrigo Co Plc	L2	Health	Drug	Pharmaceutical Preparations	4	4	M.d	329	18.86	17	28	79	D
11/14/25 08:17	11/13/25	ZOMDF	Zomedica Corp.	A0	Health	Drug	Pharmaceutical Preparations	1	4	P	47	0.0891	528	10	5,784	D
11/13/25 20:22	10/15/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	6	S.dm	-76,862	77.04	-998		3,999	I
11/13/25 20:13	11/10/25	SEPN	Septerna, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-63	18.06	-4		93	D
11/13/25 18:06	11/12/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	M.d	2,330	11.06	211		47	D
11/13/25 18:06	11/12/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S.d	-2,330	11.06	-211		47	D
11/13/25 16:41	11/11/25	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-97	4.86	-20		54	D
11/13/25 16:05	11/12/25	OGN	Organon & Co.		Health	Drug	Pharmaceutical Preparations	4	5	P.d	502	6.20	81	134	141	I
11/12/25 20:44	11/7/25	SPRO	Spero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-95	2.37	-40		869	D
11/12/25 20:36	11/10/25	LYEL	Lyell Immunopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	S	-14	16.12	-1		107	D
11/12/25 18:00	11/10/25	ASRT	Assertio Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-7	0.7597	-9		99	D
11/12/25 16:45	11/7/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	4	7	M.d	4,830	148.92	32	18	210	D
11/12/25 16:45	11/7/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	4	7	S.d	-4,830	148.92	-32		210	D
11/12/25 16:33	11/10/25	APVO	Aptevo Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	20	1.49	14	999%	14	D
11/12/25 16:26	11/7/25	EVMN	Evommune, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	P.d	70,000	16.00	4,375	70	10,644	I
11/12/25 16:13	10/7/25	EBS	Emergent Biosolutions Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-579	10.17	-57		353	D
11/12/25 16:07	11/11/25	ALT	Altimmune, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	0	0.00	19	433	23	D
11/12/25 16:01	11/10/25	MRK	Merck & Co., Inc.	NJ	Health	Drug	Pharmaceutical Preparations	2	2	S	-1,336	85.13	-16		25	D
11/10/25 21:51	11/7/25	BNTC	Benitec Biopharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	20,000	13.50	1,481	438	1,820	I
11/10/25 18:30	11/3/25	MURA	Mural Oncology Plc	L2	Health	Drug	Pharmaceutical Preparations	2	2	S	-25	2.09	-12		184	D
11/10/25 16:54	11/6/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	4	8	M.dm	14,412	23.49	614	194	930	D
11/10/25 16:54	11/6/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	4	8	S.dm	-14,412	23.49	-614		930	D
11/10/25 16:05	11/6/25	CTMX	Cytomx Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-462	4.54	-102		1,081	D
11/7/25 16:58	11/6/25	EVOK	Evoke Pharma Inc	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-96	10.65	-9		154	I
11/7/25 16:20	11/7/25	ARVN	Arvinas, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-229	7.58	-30		108	D
11/6/25 20:25	11/4/25	MBRX	Moleculin Biotech, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	M.d	2	0.0395	63	6	1,085	D
11/6/25 18:12	11/4/25	ANTX	An2 Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-4	1.14	-4		243	D
11/6/25 16:05	11/4/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	6	11	M.dm	11,044	25.49	433	109	830	D
11/6/25 16:05	11/4/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	6	11	S.dm	-11,044	25.49	-433		830	D
11/6/25 08:01	11/5/25	NVCT	Nuvectis Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	P.m	1,125	6.12	184	3	6,975	D
11/6/25 07:30	11/5/25	RLMD	Relmada Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	4	4	P	2,197	2.20	999	51	2,967	D
11/5/25 21:15	11/3/25	SYRE	Spyre Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-1,050	23.33	-45		702	D
11/5/25 19:01	11/3/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	13	M.dm	44,829	66.91	670	9	7,814	D
11/5/25 19:01	11/3/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	13	S.dm	-44,829	66.91	-670		7,814	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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