Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	#o	#f	T	TVal	Price	Qty	oc	Own	H
11/25/25 21:20	11/24/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	1	18	M.d	171	2.28	75		0	D
11/25/25 21:20	11/24/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	1	18	S.d	-171	2.28	-75	-100	0	D
11/25/25 21:00	11/24/25	TTRX	Turn Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	7	P.m	300	4.00	75	5	1,518	D
11/25/25 20:30	11/25/25	NKTR	Nektar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	3	8	S.dm	-1,076	41.09	-26		109	D
11/25/25 20:17	11/25/25	COCP	Cocrystal Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	19	0.9406	20	1	1,727	I
11/25/25 19:38	11/13/25	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	2	7	M.d	945	21.87	43	63	112	D
11/25/25 19:38	11/13/25	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	2	7	S.d	-945	21.87	-43		112	D
11/25/25 19:00	11/25/25	VRCA	Verrica Pharmaceuticals Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	5	P.d	17,973	4.24	4,236	108	8,148	D
11/25/25 18:59	11/24/25	ANVS	Annovis Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	7	P.d	2,622	2.20	1,194	43	3,979	D
11/25/25 18:42	11/24/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	26	M.dm	6,620	11.43	579	507	693	D
11/25/25 18:42	11/24/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	26	S.dm	-6,620	11.43	-579		693	D
11/25/25 18:27	11/3/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	9	25	S.dm	-9,576	19.71	-486		1,800	D
11/25/25 18:08	11/25/25	EQ	Equillium, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-8	0.9504	-8		127	D
11/25/25 18:05	11/21/25	HOWL	Werewolf Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	21	S.m	-5,028	1.19	-4,208		17,018	I
11/25/25 18:00	9/16/25	OLMA	Olema Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S.dm	-219	3.60	-61		1,247	M
11/25/25 17:35	11/21/25	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	6	10	S.dm	-349	8.73	-40		713	D
11/25/25 17:35	11/21/25	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	6	10	M.dm	349	8.73	40	6	713	D
11/25/25 17:31	11/24/25	TGTX	Tg Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-835	32.30	-26		318	D
11/25/25 17:00	11/21/25	TYRA	Tyra Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S.m	-9,139	18.14	-504		4,130	I
11/25/25 16:49	9/9/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	8	108	S.edm	-360,053	285.45	-1,261		725	D
11/25/25 16:44	8/26/25	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	9	M.d	1,024	4.72	217	8	2,828	D
11/25/25 16:44	8/26/25	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	9	S.d	-1,024	4.72	-217		2,828	D
11/25/25 16:30	11/21/25	DMAC	Diamedica Therapeutics Inc.	Z4	Health	Drug	Pharmaceutical Preparations	2	2	M.dm	5,985	5.91	1,012	15	7,852	D
11/25/25 16:17	11/25/25	ABT	Abbott Laboratories	IL	Health	Drug	Pharmaceutical Preparations	1	1	S	-203	128.02	-2		30	D
11/25/25 16:15	11/21/25	MAIA	Maia Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P.dm	37	1.18	31	1	2,355	D
11/25/25 16:11	11/21/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	4	7	S.d	-1,320	2.09	-631		1,022	D
11/25/25 16:10	11/18/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	9	M.d	6,662	30.98	215	44	702	D
11/25/25 16:10	11/21/25	HRMY	Harmony Biosciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-120	2.48	-48		21	D
11/25/25 16:06	11/24/25	SAVA	Cassava Sciences Inc	DE	Health	Drug	Pharmaceutical Preparations	3	6	P.m	1,232	2.51	491	105	960	D
11/25/25 16:05	11/21/25	VERA	Vera Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S.d	-583	20.19	-29		107	D
11/25/25 16:02	11/20/25	ALMS	Alumis Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	9	P.m	14,768	6.20	2,384	5	52,469	I
11/25/25 16:00	11/13/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	2	30	S.e	-2,011,061	595.11	-3,379		95,636	D
11/25/25 12:54	11/21/25	CVRX	Cvrx, Inc.	NJ	Health	Drug	Pharmaceutical Preparations	1	3	S.m	-573	10.20	-56		4,051	I
11/24/25 21:10	11/21/25	NTHI	Neonc Technologies Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P.m	192	6.17	31	0	10,628	D
11/24/25 20:08	11/21/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	11	22	M.dm	6,927	8.36	829	14	6,806	D
11/24/25 20:00	8/29/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	35	M.dm	107,115	78.44	1,366	8	19,309	D
11/24/25 18:46	9/4/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	17	S.dm	-50,595	51.40	-984		7,228	I
11/24/25 18:16	9/25/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	27	M.dm	22,470	30.65	733	45	2,368	D
11/24/25 18:06	11/3/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	10	S.d	-950	6.93	-137		182	D
11/24/25 18:00	11/21/25	RNXT	Renovorx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P.m	18	0.8000	22	3	756	D
11/24/25 17:47	11/18/25	JAZZ	Jazz Pharmaceuticals Plc	L2	Health	Drug	Pharmaceutical Preparations	5	9	S.dm	-9,746	163.64	-60		539	D
11/24/25 17:47	11/18/25	JAZZ	Jazz Pharmaceuticals Plc	L2	Health	Drug	Pharmaceutical Preparations	5	9	M.dm	9,746	163.64	60	12	539	D
11/24/25 17:43	9/4/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	20	M.dm	51,519	31.37	1,642	59	4,420	D
11/24/25 17:43	9/4/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	20	S.dm	-51,519	31.37	-1,642		4,420	D
11/24/25 17:08	11/20/25	SLRX	Salarius Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P	20	0.7896	25	999%	25	I
11/24/25 17:07	11/20/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	15	S.dm	-109,055	32.45	-3,361		22,520	I
11/24/25 16:42	11/20/25	GRTX	Galera Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-1	0.0201	-70		195	D
11/24/25 16:30	11/21/25	TRDA	Entrada Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	5	S.m	-5,223	8.48	-616		12,914	D
11/24/25 16:15	11/20/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	12	M.dm	9,123	65.17	140		29	D
11/24/25 16:15	11/20/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	12	S.dm	-9,123	65.17	-140		29	D
11/24/25 16:15	9/9/25	PAHC	Phibro Animal Health Corp	DE	Health	Drug	Pharmaceutical Preparations	1	11	S.dm	-8,017	42.57	-188		91	I
11/24/25 16:09	11/20/25	NUVB	Nuvation Bio Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	10	M.dm	6,229	4.33	1,438		42	D
11/24/25 16:09	11/20/25	NUVB	Nuvation Bio Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	10	S.dm	-6,229	4.33	-1,438		42	D
11/24/25 16:07	11/7/25	REGN	Regeneron Pharmaceuticals, Inc.	NY	Health	Drug	Pharmaceutical Preparations	5	7	S.dm	-37,654	561.05	-67		107	D
11/24/25 16:03	11/20/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	4	6	M.d	6,596	19.68	335	93	695	D
11/24/25 16:03	11/20/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	4	6	S.d	-6,596	19.68	-335		695	D
11/24/25 12:54	11/21/25	PHIO	Phio Pharmaceuticals Corp.	DE	Health	Drug	Pharmaceutical Preparations	1	2	P	12	1.21	10	4	281	D
11/21/25 21:52	10/30/25	ANNX	Annexon, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	5	P.m	8,690	3.72	2,335	31	9,775	D
11/21/25 21:41	9/24/25	PRAX	Praxis Precision Medicines, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	6	M.d	43,831	108.60	404	10	4,470	D
11/21/25 20:24	9/3/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	6	16	S.dm	-224,452	15.49	-14,491		121,801	D
11/21/25 19:54	11/19/25	PGEN	Precigen, Inc.	VA	Health	Drug	Pharmaceutical Preparations	6	10	S.dm	-37,956	1.39	-27,396		130,226	I
11/21/25 18:35	11/20/25	SILO	Silo Pharma, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	2	P.m	6	0.3987	14	7	212	D
11/21/25 18:13	11/20/25	SGMT	Sagimet Biosciences Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-290	7.69	-38		81	D
11/21/25 17:39	11/21/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	6	S.d	-20,298	341.80	-59		136	D
11/21/25 17:28	11/17/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	17	S.dm	-2,122	19.65	-108		2,161	I
11/21/25 17:07	11/21/25	OPK	Opko Health, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	5	P	3,192	1.32	2,423	1	250,403	I
11/21/25 17:00	10/15/25	GBIO	Generation Bio Co.	DE	Health	Drug	Pharmaceutical Preparations	5	6	M.d	0	0.00	2	1	209	D
11/21/25 16:59	9/16/25	LFVN	Lifevantage Corp		Health	Drug	Pharmaceutical Preparations	7	9	P.d	385	0.9366	411	36	1,568	D
11/21/25 16:55	11/19/25	RPRX	Royalty Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	2	2	S	-7,928	38.67	-205		1,829	M
11/21/25 16:25	11/19/25	PVLA	Palvella Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	2	M.d	406	47.17	9		0	D
11/21/25 16:25	11/19/25	PVLA	Palvella Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-406	47.17	-9	-100	0	D
11/21/25 16:15	11/19/25	FULC	Fulcrum Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-165	11.03	-15		485	D
11/21/25 16:07	11/17/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	11	M.d	302	2.00	151	25	751	D
11/21/25 16:07	11/18/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	11	S.d	-302	2.00	-151		751	D
11/21/25 16:05	11/20/25	SLGL	Sol-Gel Technologies Ltd.	L3	Health	Drug	Pharmaceutical Preparations	1	1	P	207	35.83	6	2	373	I
11/21/25 08:45	11/19/25	SLS	Sellas Life Sciences Group, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	101	1.59	63	155	104	D
11/20/25 18:38	11/18/25	TENX	Tenax Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	P.dm	108	7.41	15		13	D
11/20/25 17:12	11/18/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	14	68	M.dm	113,282	56.11	2,019		878	D
11/20/25 16:30	8/28/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	10	35	S.dm	-29,168	24.98	-1,168		10,466	I
11/20/25 16:05	11/18/25	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	5	S	-149	3.68	-40		1,934	D
11/20/25 16:00	11/19/25	LITS	Lite Strategy, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	23	1.88	12	68	30	D
11/20/25 13:42	11/19/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	3	7	S.d	-333	13.82	-24		195	D
11/20/25 07:00	11/18/25	ITRM	Iterum Therapeutics Plc	L2	Health	Drug	Pharmaceutical Preparations	1	1	P	2	0.3652	6	3	241	D
11/19/25 18:57	9/9/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	6	26	M.d	4,471	46.26	97	18	622	D
11/19/25 18:57	9/9/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	6	26	S.d	-4,471	46.26	-97		622	D
11/19/25 18:28	11/12/25	NATR	Natures Sunshine Products Inc	UT	Health	Drug	Pharmaceutical Preparations	6	10	S.m	-525	10.48	-50		456	D
11/19/25 18:00	11/17/25	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	4	7	M.d	1,135	14.70	77	252	108	D
11/19/25 18:00	11/18/25	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	4	7	S.d	-1,135	14.70	-77		108	D
11/19/25 16:57	11/12/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	6	13	M.dm	30,829	310.22	99	0	56,536	D
11/19/25 16:57	11/12/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	6	13	S.dm	-30,829	310.22	-99	0	56,536	D
11/19/25 16:39	9/29/25	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	10	S.dm	-5,095	14.08	-362		1,795	D
11/19/25 16:38	11/17/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	6	30	M.dm	29,095	22.76	1,278		409	D
11/19/25 16:38	11/17/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	6	30	S.dm	-29,095	22.76	-1,278		409	D
11/19/25 16:32	11/17/25	PCRX	Pacira Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-426	23.17	-18		244	D
11/19/25 16:21	8/27/25	AMRX	Amneal Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	3	4	S.d	-2,816	8.14	-346		663	D
11/19/25 16:06	11/17/25	VRTX	Vertex Pharmaceuticals Inc / Ma	MA	Health	Drug	Pharmaceutical Preparations	4	5	S.dm	-40,255	268.29	-150		62	D
11/19/25 16:06	11/17/25	CYPH	Cypherpunk Technologies Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-5,069	3.14	-1,614		132	I
11/19/25 16:05	11/17/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	6	12	M.dm	43,053	322.22	134	218	195	D
11/19/25 16:05	11/17/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	6	12	S.dm	-43,053	322.22	-134		195	D
11/19/25 16:05	11/17/25	IRWD	Ironwood Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-20	3.32	-6		235	D
11/19/25 16:01	11/11/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	4	24	S.dm	-2,757	4.12	-669		6,727	D
11/19/25 16:01	11/17/25	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	2	5	S.d	-1,787	51.48	-35		90	D
11/19/25 07:46	11/17/25	CRVO	Cervomed Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	10	P.m	738	8.02	92	3	3,021	D
11/18/25 21:45	11/14/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	11	S.dm	-3,345	8.44	-396		1,225	D
11/18/25 19:04	11/15/25	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	M.d	250	2.52	99	5	2,194	D
11/18/25 19:04	11/17/25	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	S.d	-250	2.52	-99		2,194	D
11/18/25 17:30	11/14/25	RNTX	Rein Therapeutics, Inc.		Health	Drug	Pharmaceutical Preparations	1	2	P.m	551	1.34	410	40	1,426	I
11/18/25 16:30	11/15/25	MCRB	Seres Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	M.d	45	3.73	12	53	35	D
11/18/25 16:30	11/15/25	MCRB	Seres Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	S.d	-45	3.73	-12		35	D
11/18/25 16:27	9/8/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	11	M.d	5,013	25.15	199	17	1,375	D
11/18/25 16:27	9/8/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	11	S.d	-5,013	25.15	-199		1,375	D
11/18/25 16:26	11/18/25	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	5	S	-21	1.10	-19		858	D
11/18/25 16:22	10/3/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	13	M.dm	5,414	20.44	265	109	508	D
11/18/25 16:22	10/3/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	13	S.dm	-5,414	20.44	-265		508	D
11/18/25 16:21	11/3/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	6	15	M.d	84,501	103.67	815		588	D
11/18/25 16:21	11/3/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	6	15	S.d	-84,501	103.67	-815		588	D
11/18/25 16:18	11/17/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	3	21	M.dm	7,768	16.23	479		438	D
11/18/25 16:18	11/17/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	3	21	S.dm	-7,768	16.23	-479		438	D
11/18/25 16:15	11/18/25	BIXT	Bioxytran, Inc	NV	Health	Drug	Pharmaceutical Preparations	1	1	P	126	0.6000	210	50	626	D
11/18/25 10:05	11/17/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	14	S.dm	-11,119	25.75	-432		2,278	D
11/18/25 07:29	11/13/25	BHVN	Biohaven Ltd.	D8	Health	Drug	Pharmaceutical Preparations	4	4	P	33,145	7.50	4,417	39	15,825	D
11/17/25 18:01	9/19/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	5	7	S.m	-2,964	90.17	-33		449	D
11/17/25 17:58	9/11/25	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	4	6	S.dm	-1,213	5.04	-241		4,440	D
11/17/25 16:48	11/13/25	MRVI	Maravai Lifesciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	P.m	1,512	3.24	467	23	2,467	I
11/17/25 16:42	11/13/25	FGEN	Fibrogen Inc	DE	Health	Drug	Pharmaceutical Preparations	1	1	P.m	34	9.12	4	17	25	D
11/17/25 16:38	11/14/25	SVRA	Savara Inc	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	9	1.46	6	5	121	D
11/17/25 16:05	11/14/25	AVTX	Avalo Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-244	12.47	-20	-100	0	D
11/17/25 16:05	11/14/25	AVTX	Avalo Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	M.d	244	12.47	20		0	D
11/17/25 08:01	11/13/25	CATX	Perspective Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P	42	2.06	20	13	179	D
11/14/25 21:00	11/13/25	DNTH	Dianthus Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	2	4	M.dm	11,247	25.97	433		4	D
11/14/25 21:00	11/13/25	DNTH	Dianthus Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.dm	-11,247	25.97	-433		4	D
11/14/25 21:00	11/13/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	2	2	P	116	6.78	17	0	18,245	I
11/14/25 20:00	11/14/25	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	4	M.d	749	18.73	40	89	85	D
11/14/25 20:00	11/14/25	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	4	S.d	-749	18.73	-40		85	D
11/14/25 20:00	9/8/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	12	P	1,607	9.31	173	12	1,615	D
11/14/25 20:00	11/14/25	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-345	5.25	-66		1,487	D
11/14/25 18:43	11/12/25	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	M.d	1,705	7.10	240		11	D
11/14/25 18:43	11/12/25	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.d	-1,705	7.10	-240		11	D
11/14/25 16:30	11/13/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	6	S.m	-410	5.22	-79		2,066	D
11/14/25 16:10	11/6/25	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	3	4	S.d	-3,965	33.84	-117		262	D
11/14/25 16:04	10/30/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	17	M.d	907	27.33	33	41	114	D
11/14/25 16:04	10/30/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	17	S.d	-907	27.33	-33		114	D
11/14/25 10:45	9/9/25	PRGO	Perrigo Co Plc	L2	Health	Drug	Pharmaceutical Preparations	4	4	M.d	329	18.86	17	28	79	D
11/14/25 08:17	11/13/25	ZOMDF	Zomedica Corp.	A0	Health	Drug	Pharmaceutical Preparations	1	4	P	47	0.0891	528	10	5,784	D
11/14/25 06:00	11/11/25	TBPH	Theravance Biopharma, Inc.	CA	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-1,878	18.05	-104		60	D
11/13/25 20:22	10/15/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	6	S.dm	-76,862	77.04	-998		3,999	I
11/13/25 20:13	11/10/25	SEPN	Septerna, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-63	18.06	-4		93	D
11/13/25 18:06	11/12/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	5	M.d	3,808	9.27	411		47	D
11/13/25 18:06	11/12/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	5	S.d	-3,808	9.27	-411		47	D
11/13/25 16:41	11/11/25	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-97	4.86	-20		54	D
11/13/25 16:05	11/12/25	OGN	Organon & Co.		Health	Drug	Pharmaceutical Preparations	4	5	P.d	502	6.20	81	134	141	I
11/12/25 20:44	11/7/25	SPRO	Spero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-112	2.30	-49		2,312	D
11/12/25 20:36	11/10/25	LYEL	Lyell Immunopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	S	-14	16.12	-1		107	D
11/12/25 18:00	11/10/25	ASRT	Assertio Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-7	0.7597	-9		99	D
11/12/25 16:45	11/7/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	4	8	M.d	4,906	149.11	33	19	210	D
11/12/25 16:45	11/7/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	4	8	S.d	-4,906	149.11	-33		210	D
11/12/25 16:33	11/10/25	APVO	Aptevo Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	20	1.49	14	999%	14	D
11/12/25 16:26	11/7/25	EVMN	Evommune, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	P.d	70,000	16.00	4,375	70	10,644	I
11/12/25 16:13	10/7/25	EBS	Emergent Biosolutions Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-579	10.17	-57		353	D
11/12/25 16:07	11/11/25	ALT	Altimmune, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	0	0.00	19	433	23	D
11/12/25 16:01	11/10/25	MRK	Merck & Co., Inc.	NJ	Health	Drug	Pharmaceutical Preparations	2	2	S	-1,336	85.13	-16		25	D
11/12/25 06:05	11/7/25	GLSI	Greenwich Lifesciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	P	111	8.58	13	0	5,584	D
11/10/25 21:51	11/7/25	BNTC	Benitec Biopharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	20,000	13.50	1,481	438	1,820	I
11/10/25 18:30	11/3/25	MURA	Mural Oncology Plc	L2	Health	Drug	Pharmaceutical Preparations	2	2	S	-25	2.09	-12		184	D
11/10/25 16:54	11/6/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	4	8	M.dm	14,412	23.49	614	194	930	D
11/10/25 16:54	11/6/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	4	8	S.dm	-14,412	23.49	-614		930	D
11/10/25 16:05	11/6/25	CTMX	Cytomx Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-462	4.54	-102		1,081	D
11/7/25 17:10	11/5/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	6	26	M.dm	22,252	54.30	410	16	2,962	D
11/7/25 17:10	11/5/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	6	26	S.dm	-22,252	54.30	-410		2,962	D
11/7/25 16:58	11/6/25	EVOK	Evoke Pharma Inc	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-96	10.65	-9		154	I
11/7/25 16:20	11/7/25	ARVN	Arvinas, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-229	7.58	-30		108	D
11/7/25 16:01	11/5/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	5	5	S	-651	11.18	-58		1,014	D
11/6/25 20:25	11/4/25	MBRX	Moleculin Biotech, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	M.d	2	0.0395	63	6	1,085	D
11/6/25 18:12	11/4/25	ANTX	An2 Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-4	1.14	-4		243	D
11/6/25 16:05	11/4/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	6	12	M.dm	11,052	25.48	434	109	830	D
11/6/25 16:05	11/4/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	6	12	S.dm	-11,052	25.48	-434		830	D
11/6/25 08:01	11/5/25	NVCT	Nuvectis Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	P.m	1,125	6.12	184	3	6,975	D
11/6/25 07:30	11/5/25	RLMD	Relmada Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	4	5	P.m	2,375	1.88	1,264	74	2,967	D
11/6/25 07:00	9/2/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	19	M.dm	9,288	25.76	361	18	2,392	D
11/6/25 07:00	9/2/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	19	S.dm	-9,288	25.76	-361		2,392	D
11/5/25 21:15	11/3/25	SYRE	Spyre Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-1,349	21.27	-63		800	D
11/5/25 19:01	9/2/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	15	S.dm	-53,797	72.36	-743		7,885	D
11/5/25 18:17	10/1/25	TERN	Terns Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S.d	-675	13.51	-50		52	D
11/5/25 18:00	11/5/25	BGMS	Bio Green Med Solution, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	18	S.dm	-5,100	3.12	-1,633		1,679	D
11/5/25 17:00	9/2/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	9	M.d	1,751	29.19	60	4	1,417	D
11/5/25 17:00	9/2/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	9	S.d	-1,751	29.19	-60		1,417	D
11/5/25 16:30	11/3/25	PHAT	Phathom Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S.d	-13	0.1391	-91		97	D
11/5/25 16:05	11/4/25	FOLD	Amicus Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-244	9.51	-26		323	D
11/5/25 09:57	11/3/25	MTSR	Metsera, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S	-21	46.56	0	0	4,325	I
11/4/25 17:18	10/2/25	BMY	Bristol Myers Squibb Co	DE	Health	Drug	Pharmaceutical Preparations	6	6	M.d	2,650	34.28	77	28	349	D
11/4/25 12:35	10/31/25	HRTX	Heron Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	3	6	M.d	0	0.00	80	10	869	D
11/3/25 20:00	10/31/25	BTAI	Bioxcel Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	7	M.dm	0	0.00	6	1	541	D
11/3/25 17:25	5/14/25	ORGO	Organogenesis Holdings Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	P.m	1,177	3.09	381	3	12,249	I
11/3/25 17:25	6/9/25	ORGO	Organogenesis Holdings Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.m	-1,177	3.09	-381		12,249	I
11/3/25 16:37	11/3/25	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	1	4	M.d	751	26.81	28	61	74	D
11/3/25 16:37	11/3/25	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	1	4	S.d	-751	26.81	-28		74	D
10/31/25 15:30	10/29/25	SYBX	Synlogic, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	0	1.81	0		13	D
10/31/25 09:13	10/30/25	ANIX	Anixa Biosciences Inc	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	584	2.92	200	49	610	D
10/30/25 16:31	10/28/25	MPLT	Maplight Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P.d	108,700	17.00	6,394	38	23,384	I
10/29/25 16:11	10/27/25	PMVP	Pmv Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	M.d	2,722	1.58	1,721	32	7,102	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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