Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	#o	#f	T	TVal	Price	Qty	oc	Own	H
12/9/25 20:00	8/21/25	GNLX	Genelux Corp	DE	Health	Drug	Pharmaceutical Preparations	2	2	S.m	-59	4.76	-12		561	D
12/9/25 19:40	12/5/25	XENE	Xenon Pharmaceuticals Inc.	A1	Health	Drug	Pharmaceutical Preparations	1	4	S.dm	-2,343	31.12	-75		46	D
12/9/25 19:13	12/5/25	ALMS	Alumis Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	12	P.m	19,952	6.64	3,006	6	53,091	I
12/9/25 19:07	12/9/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	3	18	S.d	-5,671	18.17	-312		430	D
12/9/25 18:16	11/21/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	21	M.dm	695	2.81	247	42	830	D
12/9/25 18:16	11/24/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	21	S.dm	-695	2.81	-247		830	D
12/9/25 18:09	9/19/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	5	7	S.m	-2,418	88.31	-27		452	D
12/9/25 18:04	10/1/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	S	-2,635	43.92	-60		416	D
12/9/25 18:01	10/7/25	EBS	Emergent Biosolutions Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	5	S.d	-972	9.28	-105		452	D
12/9/25 17:35	10/6/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	M.dm	3,228	10.08	320	44	1,051	D
12/9/25 17:35	10/6/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	S.dm	-3,228	10.08	-320		1,051	D
12/9/25 17:25	12/5/25	JAZZ	Jazz Pharmaceuticals Plc	L2	Health	Drug	Pharmaceutical Preparations	5	12	S.dm	-33,746	155.00	-218		518	D
12/9/25 17:25	12/5/25	JAZZ	Jazz Pharmaceuticals Plc	L2	Health	Drug	Pharmaceutical Preparations	5	12	M.dm	33,746	155.00	218	73	518	D
12/9/25 17:07	12/2/25	HOWL	Werewolf Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	28	S.m	-5,968	1.15	-5,206		17,018	I
12/9/25 17:03	12/5/25	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	6	13	S.dm	-536	9.23	-58		713	D
12/9/25 17:00	12/5/25	RPRX	Royalty Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	3	7	S	-21,047	39.17	-537		2,057	M
12/9/25 16:57	12/5/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	18	M.dm	59,707	33.63	1,775	18	11,566	D
12/9/25 16:57	12/5/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	18	S.dm	-59,707	33.63	-1,775		11,566	D
12/9/25 16:54	12/8/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	6	115	M.edm	426,037	291.65	1,461		702	I
12/9/25 16:54	12/8/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	6	115	S.edm	-426,037	291.65	-1,461		702	I
12/9/25 16:51	12/5/25	MAIA	Maia Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	11	P.dm	325	1.09	298	11	2,920	I
12/9/25 16:36	11/13/25	MRVI	Maravai Lifesciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	P.m	1,880	3.32	567	26	2,732	I
12/9/25 16:22	11/6/25	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	3	4	S.d	-3,466	33.53	-103		244	D
12/9/25 16:12	12/5/25	SLGL	Sol-Gel Technologies Ltd.	L3	Health	Drug	Pharmaceutical Preparations	1	4	P.m	532	37.11	14	4	382	I
12/9/25 16:10	12/5/25	HRMY	Harmony Biosciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	4	M.d	1,491	16.87	88		21	D
12/9/25 16:10	12/5/25	HRMY	Harmony Biosciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	4	S.d	-1,491	16.87	-88		21	D
12/9/25 16:05	11/3/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	7	17	M.d	58,972	125.76	469	66	1,176	D
12/9/25 16:05	11/3/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	7	17	S.d	-58,972	125.76	-469		1,176	D
12/8/25 20:05	12/8/25	ANVS	Annovis Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	8	P.d	2,816	2.27	1,239	44	4,024	D
12/8/25 19:38	12/8/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	4	9	M.d	5,063	144.92	35	20	212	D
12/8/25 17:54	12/4/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	15	S.dm	-47,512	56.80	-836		7,147	I
12/8/25 17:28	12/8/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	8	32	M.d	12,220	45.94	266	57	734	D
12/8/25 17:28	12/8/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	8	32	S.d	-12,220	45.94	-266		734	D
12/8/25 17:15	11/21/25	DMAC	Diamedica Therapeutics Inc.	Z4	Health	Drug	Pharmaceutical Preparations	2	2	M.dm	7,658	7.14	1,073	14	8,914	D
12/8/25 16:39	12/4/25	SNSE	Sensei Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S.m	-465	10.93	-43		323	D
12/8/25 16:30	12/4/25	XOMA	Xoma Royalty Corp	NV	Health	Drug	Pharmaceutical Preparations	4	7	P.d	2,661	15.60	171	150	285	D
12/8/25 16:30	12/4/25	CBIO	Crescent Biopharma, Inc.	E9	Health	Drug	Pharmaceutical Preparations	1	1	P.d	18,238	13.41	1,360	98	2,748	I
12/8/25 16:07	12/4/25	RNAC	Cartesian Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P.d	231	6.15	38	47	117	D
12/8/25 13:21	12/2/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	4	26	S.dm	-4,529	4.62	-981		6,727	D
12/8/25 07:00	12/5/25	RNXT	Renovorx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	P.m	27	0.8500	32	4	766	D
12/5/25 20:51	12/3/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	22	M.dm	6,011	18.92	318	187	488	D
12/5/25 20:51	12/4/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	22	S.dm	-6,011	18.92	-318		488	D
12/5/25 20:00	12/4/25	DNTH	Dianthus Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	2	4	M.dm	11,450	26.44	433		4	D
12/5/25 20:00	12/4/25	DNTH	Dianthus Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.dm	-11,450	26.44	-433		4	D
12/5/25 18:53	12/5/25	ENTA	Enanta Pharmaceuticals Inc		Health	Drug	Pharmaceutical Preparations	7	9	S	-183	14.22	-13		1,346	D
12/5/25 18:20	12/4/25	BIOA	Bioage Labs, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	M.d	985	7.15	138		0	D
12/5/25 18:20	12/4/25	BIOA	Bioage Labs, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-985	7.15	-138	-100	0	D
12/5/25 18:02	12/3/25	TBPH	Theravance Biopharma, Inc.	CA	Health	Drug	Pharmaceutical Preparations	2	4	S.d	-3,050	18.53	-165		338	D
12/5/25 17:46	11/18/25	TENX	Tenax Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	5	P.dm	154	7.84	20	999%	20	D
12/5/25 16:21	12/3/25	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	1	7	M.d	1,053	26.65	39	115	74	D
12/5/25 16:21	12/3/25	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	1	7	S.d	-1,053	26.65	-39		74	D
12/5/25 16:16	12/3/25	VRTX	Vertex Pharmaceuticals Inc / Ma	MA	Health	Drug	Pharmaceutical Preparations	5	9	S.dm	-82,886	279.84	-296		141	D
12/5/25 16:15	11/26/25	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	13	M.dm	7,326	16.21	452	34	1,792	D
12/5/25 16:15	11/26/25	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	13	S.dm	-7,326	16.21	-452		1,792	D
12/5/25 16:11	12/5/25	DYN	Dyne Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-76	20.72	-4		451	D
12/4/25 21:30	12/2/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	11	M.d	2,728	8.16	334	63	868	D
12/4/25 21:30	12/2/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	11	S.d	-2,728	8.16	-334		868	D
12/4/25 19:56	11/24/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	1	22	M.dm	218	2.19	100		6	D
12/4/25 19:56	11/24/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	1	22	S.dm	-218	2.19	-100		6	D
12/4/25 19:39	12/2/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	12	M.dm	55,694	68.75	810	12	7,352	D
12/4/25 19:39	12/2/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	12	S.dm	-55,694	68.75	-810		7,352	D
12/4/25 19:32	12/2/25	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	4	6	M.d	2,938	5.09	577	14	4,834	D
12/4/25 19:32	12/2/25	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	4	6	S.d	-2,938	5.09	-577		4,834	D
12/4/25 19:00	12/2/25	QTTB	Q32 Bio Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-109	3.46	-32		139	D
12/4/25 18:55	12/2/25	SVRA	Savara Inc	DE	Health	Drug	Pharmaceutical Preparations	2	2	M.d	17	1.46	12	7	188	D
12/4/25 18:34	12/3/25	PAHC	Phibro Animal Health Corp	DE	Health	Drug	Pharmaceutical Preparations	1	13	S.dm	-8,286	42.80	-194		91	I
12/4/25 17:26	12/3/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	9	M.d	21,899	194.05	113	138	194	D
12/4/25 17:26	12/4/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	9	S.d	-21,899	194.05	-113		194	D
12/4/25 17:15	12/2/25	SONN	Sonnet Biotherapeutics Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	0	0.00	250		0	D
12/4/25 16:50	12/2/25	ACRS	Aclaris Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	0	0.00	27		27	D
12/4/25 16:15	12/2/25	BMEA	Biomea Fusion, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P.m	154	1.02	150	6	2,658	D
12/4/25 16:05	12/3/25	VERA	Vera Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	5	M.d	1,138	23.29	49	61	129	D
12/4/25 16:05	12/3/25	VERA	Vera Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	5	S.d	-1,138	23.29	-49		129	D
12/4/25 16:01	12/2/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	4	7	M.d	7,877	20.26	389	131	687	D
12/3/25 21:52	12/1/25	SYRE	Spyre Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S	-1,485	24.75	-60		702	D
12/3/25 21:19	12/2/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	5	25	M.dm	23,390	57.98	403	16	2,915	M
12/3/25 21:19	12/2/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	5	25	S.dm	-23,390	57.98	-403		2,915	M
12/3/25 20:11	12/1/25	FOLD	Amicus Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	10	M.dm	3,757	8.80	427	21	2,422	D
12/3/25 20:11	12/1/25	FOLD	Amicus Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	10	S.dm	-3,757	8.80	-427		2,422	D
12/3/25 20:00	12/1/25	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	6	M.d	894	19.16	47	122	85	D
12/3/25 20:00	12/1/25	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	6	S.d	-894	19.16	-47		85	D
12/3/25 19:01	12/1/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	12	43	S.dm	-62,680	63.07	-994		715	I
12/3/25 17:24	11/3/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	9	23	S.dm	-9,011	20.89	-431		1,747	D
12/3/25 17:02	12/1/25	NUVB	Nuvation Bio Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	14	M.dm	8,069	4.54	1,778		42	D
12/3/25 17:02	12/1/25	NUVB	Nuvation Bio Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	14	S.dm	-8,069	4.54	-1,778		42	D
12/3/25 16:39	12/1/25	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	6	S	-1,414	14.44	-98		7,288	D
12/3/25 16:30	12/1/25	ANNX	Annexon, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	P.m	8,838	3.73	2,368	32	9,812	D
12/3/25 16:30	12/1/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	6	12	M.dm	12,058	25.51	473	132	830	D
12/3/25 16:30	12/1/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	6	12	S.dm	-12,058	25.51	-473		830	D
12/3/25 16:28	10/1/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	9	M.d	1,816	30.27	60	5	1,388	D
12/3/25 16:28	10/1/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	9	S.d	-1,816	30.27	-60		1,388	D
12/3/25 16:16	12/2/25	TRVI	Trevi Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	2	0.5110	4	19	26	D
12/2/25 18:45	11/28/25	PHAT	Phathom Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	M.d	7	0.0392	181		138	D
12/2/25 17:14	9/11/25	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	3	5	S.dm	-682	4.06	-168		4,215	D
12/2/25 16:43	11/28/25	PBH	Prestige Consumer Healthcare Inc.		Health	Drug	Pharmaceutical Preparations	1	1	S.m	-60	60.00	-1		42	D
12/2/25 16:34	11/28/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	9	32	M.d	6,729	18.19	370	9	4,503	D
12/2/25 16:34	12/1/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	9	32	S.d	-6,729	18.19	-370		4,503	D
12/2/25 16:30	11/24/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	37	S.dm	-108,476	78.83	-1,376		19,309	I
12/2/25 16:04	11/18/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	9	M.d	10,110	35.97	281	67	702	D
12/1/25 17:17	11/26/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	7	8	M.d	287	10.76	27	21	151	D
12/1/25 16:57	11/12/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	4	11	M.dm	29,039	308.34	94	0	54,838	D
12/1/25 16:57	11/12/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	4	11	S.dm	-29,039	308.34	-94	0	54,838	D
12/1/25 16:37	11/26/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	5	21	M.dm	22,598	23.63	956		387	D
12/1/25 16:37	11/26/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	5	21	S.dm	-22,598	23.63	-956		387	D
12/1/25 16:17	11/26/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	10	M.d	4,893	24.99	196	17	1,365	D
12/1/25 16:17	11/26/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	10	S.d	-4,893	24.99	-196		1,365	D
12/1/25 16:15	11/26/25	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	2	3	P.d	7,874	176.18	45		13	D
12/1/25 16:10	11/26/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	5	10	M.dm	31,767	321.41	99	100	198	D
12/1/25 16:07	11/26/25	CVRX	Cvrx, Inc.	NJ	Health	Drug	Pharmaceutical Preparations	1	4	S.m	-637	10.18	-63		4,051	I
12/1/25 09:07	11/28/25	KTTA	Pasithea Therapeutics Corp.	DE	Health	Drug	Pharmaceutical Preparations	3	3	P	150	0.7500	200	184	309	D
11/28/25 17:38	11/25/25	BHC	Bausch Health Companies Inc.	NJ	Health	Drug	Pharmaceutical Preparations	1	1	P	15,625	6.25	2,500	4	73,256	I
11/28/25 17:00	11/26/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	11	14	M.d	1,210	10.17	119	2	6,769	D
11/28/25 17:00	11/26/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	11	14	S.d	-1,210	10.17	-119		6,769	D
11/28/25 16:05	11/25/25	MRUS	Merus N.V.	P7	Health	Drug	Pharmaceutical Preparations	1	2	M.d	796	47.96	17		11	D
11/28/25 16:05	11/25/25	MRUS	Merus N.V.	P7	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-796	47.96	-17		11	D
11/28/25 09:00	11/26/25	COCP	Cocrystal Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	P	23	0.9495	24	1	1,731	I
11/28/25 06:05	11/25/25	GLSI	Greenwich Lifesciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	3	P	149	8.52	18	0	5,588	D
11/28/25 06:03	11/25/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	17	M.dm	8,621	18.12	476	23	2,510	D
11/26/25 18:24	11/24/25	ORGO	Organogenesis Holdings Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	3	S.m	-2,769	4.06	-681		12,249	D
11/26/25 16:30	11/25/25	ADTX	Aditxt, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	0	3.00	0	-100	0	D
11/26/25 16:02	11/24/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	6	8	S	-973	11.45	-85		4,441	D
11/26/25 16:00	11/13/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	2	31	S.e	-2,010,362	567.74	-3,541		95,635	D
11/26/25 14:58	11/26/25	ABCL	Abcellera Biologics Inc.	A1	Health	Drug	Pharmaceutical Preparations	1	1	P	178	3.57	50	28	226	D
11/25/25 21:00	11/24/25	TTRX	Turn Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	7	P.m	300	4.00	75	5	1,518	D
11/25/25 20:30	11/25/25	NKTR	Nektar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	3	3	S.d	-217	54.28	-4		95	D
11/25/25 19:38	11/13/25	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	2	6	M.d	929	21.76	43	62	111	D
11/25/25 19:38	11/13/25	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	2	6	S.d	-929	21.76	-43		111	D
11/25/25 19:00	11/25/25	VRCA	Verrica Pharmaceuticals Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	5	P.d	17,973	4.24	4,236	108	8,148	D
11/25/25 18:42	11/24/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	26	M.dm	6,620	11.43	579	507	693	D
11/25/25 18:42	11/24/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	26	S.dm	-6,620	11.43	-579		693	D
11/25/25 18:08	11/25/25	EQ	Equillium, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-8	0.9504	-8		127	D
11/25/25 18:00	9/16/25	OLMA	Olema Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S.dm	-219	3.60	-61		1,247	M
11/25/25 17:31	11/24/25	TGTX	Tg Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-835	32.30	-26		318	D
11/25/25 17:00	11/21/25	TYRA	Tyra Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S.m	-9,139	18.14	-504		4,130	I
11/25/25 16:44	11/21/25	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	6	S	-453	5.54	-82		2,816	D
11/25/25 16:17	11/25/25	ABT	Abbott Laboratories	IL	Health	Drug	Pharmaceutical Preparations	1	1	S	-203	128.02	-2		30	D
11/25/25 16:11	11/21/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	3	6	S.d	-595	22.48	-26		132	D
11/25/25 16:06	11/24/25	SAVA	Cassava Sciences Inc	DE	Health	Drug	Pharmaceutical Preparations	3	6	P.m	1,232	2.51	491	105	960	D
11/24/25 21:10	11/21/25	NTHI	Neonc Technologies Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P.m	192	6.17	31	0	10,628	D
11/24/25 18:16	9/25/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	20	M.d	15,107	30.48	496	27	2,358	D
11/24/25 18:06	11/3/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	10	S.d	-950	6.93	-137		182	D
11/24/25 17:08	11/20/25	SLRX	Salarius Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P	20	0.7896	25	999%	25	I
11/24/25 17:07	11/20/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	13	S.dm	-64,055	40.13	-1,596		8,934	I
11/24/25 16:42	11/20/25	GRTX	Galera Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-1	0.0201	-70		195	D
11/24/25 16:30	11/21/25	TRDA	Entrada Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	5	S.m	-5,223	8.48	-616		12,914	D
11/24/25 16:15	11/20/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	10	M.dm	6,849	64.35	106		29	D
11/24/25 16:15	11/20/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	10	S.dm	-6,849	64.35	-106		29	D
11/24/25 16:07	11/7/25	REGN	Regeneron Pharmaceuticals, Inc.	NY	Health	Drug	Pharmaceutical Preparations	5	7	S.dm	-37,654	561.05	-67		107	D
11/24/25 12:54	11/21/25	PHIO	Phio Pharmaceuticals Corp.	DE	Health	Drug	Pharmaceutical Preparations	1	2	P	12	1.21	10	4	281	D
11/21/25 21:41	9/24/25	PRAX	Praxis Precision Medicines, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	6	M.d	43,831	108.60	404	10	4,470	D
11/21/25 20:24	11/13/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	6	15	S.dm	-201,995	15.89	-12,716		119,947	D
11/21/25 19:54	11/19/25	PGEN	Precigen, Inc.	VA	Health	Drug	Pharmaceutical Preparations	5	8	S.dm	-37,789	1.38	-27,355		130,008	I
11/21/25 18:35	11/20/25	SILO	Silo Pharma, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	2	P.m	6	0.3987	14	7	212	D
11/21/25 18:13	11/20/25	SGMT	Sagimet Biosciences Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-290	7.69	-38		81	D
11/21/25 17:28	11/17/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	14	S.dm	-1,912	20.16	-95		2,155	I
11/21/25 17:07	11/21/25	OPK	Opko Health, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	5	P	3,192	1.32	2,423	1	250,403	I
11/21/25 17:00	10/15/25	GBIO	Generation Bio Co.	DE	Health	Drug	Pharmaceutical Preparations	5	6	M.d	0	0.00	2	1	209	D
11/21/25 16:59	9/16/25	LFVN	Lifevantage Corp		Health	Drug	Pharmaceutical Preparations	2	3	P	335	6.84	49	30	215	D
11/21/25 16:25	11/19/25	PVLA	Palvella Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	2	M.d	406	47.17	9		0	D
11/21/25 16:25	11/19/25	PVLA	Palvella Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-406	47.17	-9	-100	0	D
11/21/25 16:15	11/19/25	FULC	Fulcrum Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-165	11.03	-15		485	D
11/21/25 08:45	11/19/25	SLS	Sellas Life Sciences Group, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	101	1.59	63	155	104	D
11/20/25 16:05	11/18/25	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	5	S	-149	3.68	-40		1,934	D
11/20/25 16:00	11/19/25	LITS	Lite Strategy, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	23	1.88	12	68	30	D
11/20/25 07:00	11/18/25	ITRM	Iterum Therapeutics Plc	L2	Health	Drug	Pharmaceutical Preparations	1	1	P	2	0.3652	6	3	241	D
11/19/25 18:28	11/12/25	NATR	Natures Sunshine Products Inc	UT	Health	Drug	Pharmaceutical Preparations	6	9	S	-363	8.99	-40		456	D
11/19/25 18:00	11/17/25	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	3	6	M.d	1,094	14.46	76	999%	82	D
11/19/25 18:00	11/18/25	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	3	6	S.d	-1,094	14.46	-76		82	D
11/19/25 16:32	11/17/25	PCRX	Pacira Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-362	22.58	-16		235	D
11/19/25 16:21	11/17/25	AMRX	Amneal Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	2	3	S.d	-2,520	8.03	-314		437	D
11/19/25 16:06	11/17/25	CYPH	Cypherpunk Technologies Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-5,069	3.14	-1,614		132	I
11/19/25 16:05	11/17/25	IRWD	Ironwood Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-20	3.32	-6		235	D
11/19/25 16:01	11/17/25	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.d	-1,550	50.47	-31		86	D
11/19/25 07:46	11/17/25	CRVO	Cervomed Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	10	P.m	738	8.02	92	3	3,021	D
11/18/25 19:04	11/15/25	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	M.d	250	2.52	99	5	2,194	D
11/18/25 19:04	11/17/25	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	S.d	-250	2.52	-99		2,194	D
11/18/25 17:30	11/14/25	RNTX	Rein Therapeutics, Inc.		Health	Drug	Pharmaceutical Preparations	1	2	P.m	551	1.34	410	40	1,426	I
11/18/25 16:30	11/15/25	MCRB	Seres Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	M.d	45	3.73	12	53	35	D
11/18/25 16:30	11/15/25	MCRB	Seres Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	S.d	-45	3.73	-12		35	D
11/18/25 16:26	11/18/25	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	5	S	-21	1.10	-19		858	D
11/18/25 16:15	11/18/25	BIXT	Bioxytran, Inc	NV	Health	Drug	Pharmaceutical Preparations	1	1	P	126	0.6000	210	50	626	D
11/18/25 10:05	11/17/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	10	S.d	-3,410	22.97	-148		632	D
11/18/25 07:29	11/13/25	BHVN	Biohaven Ltd.	D8	Health	Drug	Pharmaceutical Preparations	4	4	P	33,145	7.50	4,417	39	15,825	D
11/17/25 16:42	11/13/25	FGEN	Fibrogen Inc	DE	Health	Drug	Pharmaceutical Preparations	1	1	P.m	34	9.12	4	17	25	D
11/17/25 16:05	11/14/25	AVTX	Avalo Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-244	12.47	-20	-100	0	D
11/17/25 16:05	11/14/25	AVTX	Avalo Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	M.d	244	12.47	20		0	D
11/17/25 08:01	11/13/25	CATX	Perspective Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P	42	2.06	20	13	179	D
11/14/25 21:00	11/13/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	2	2	P	116	6.78	17	0	18,245	I
11/14/25 20:00	11/14/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	11	S	-1,197	9.76	-123		1,615	D
11/14/25 18:43	11/12/25	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	M.d	1,705	7.10	240		11	D
11/14/25 18:43	11/12/25	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.d	-1,705	7.10	-240		11	D
11/14/25 16:30	11/13/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	6	S.m	-410	5.22	-79		2,066	D
11/14/25 16:04	10/30/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	14	M.d	580	23.94	24	27	113	D
11/14/25 16:04	10/30/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	14	S.d	-580	23.94	-24		113	D
11/14/25 10:45	11/12/25	PRGO	Perrigo Co Plc	L2	Health	Drug	Pharmaceutical Preparations	1	1	P	106	14.18	8	12	72	I
11/14/25 08:17	11/13/25	ZOMDF	Zomedica Corp.	A0	Health	Drug	Pharmaceutical Preparations	1	4	P	47	0.0891	528	10	5,784	D
11/13/25 20:22	10/15/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	5	S.dm	-76,852	77.81	-988		3,827	I
11/13/25 20:13	11/10/25	SEPN	Septerna, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-63	18.06	-4		93	D
11/13/25 18:06	11/12/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	M.d	2,330	11.06	211		47	D
11/13/25 18:06	11/12/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S.d	-2,330	11.06	-211		47	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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