Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	#o	#f	T	TVal	Price	Qty	oc	Own	H
9/17/25 20:08	9/15/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	12	S.dm	-12,009	21.93	-548		2,316	D
9/17/25 19:39	9/16/25	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-577	4.45	-130		2,704	D
9/17/25 19:00	9/2/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	12	S.dm	-29,877	81.06	-369		7,945	D
9/17/25 18:58	8/1/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	S.d	-229	3.67	-62		165	D
9/17/25 18:06	9/16/25	TNGX	Tango Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	4	S.m	-17,496	7.01	-2,495		15,759	D
9/17/25 17:22	9/8/25	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	4	12	P.dm	11,804	18.22	648	10	6,976	I
9/17/25 17:20	9/17/25	IMMX	Immix Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P	10	1.99	5	0	1,727	D
9/17/25 17:01	9/15/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	M.d	268	8.47	32		0	D
9/17/25 17:01	9/15/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-268	8.47	-32	-100	0	D
9/17/25 16:45	9/15/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	9	29	M.dm	27,861	21.65	1,287		530	D
9/17/25 16:45	9/15/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	9	29	S.dm	-27,861	21.65	-1,287		530	D
9/17/25 16:31	8/29/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	25	M.dm	16,155	49.83	324	322	425	D
9/17/25 16:30	9/9/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	12	42	S.dm	-87,356	255.13	-342		764	D
9/17/25 16:30	8/28/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	11	37	S.dm	-26,286	24.27	-1,083		10,662	I
9/17/25 16:15	9/8/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	8	M.d	2,258	22.34	101	17	679	D
9/17/25 16:15	9/8/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	8	S.d	-2,258	22.34	-101		679	D
9/17/25 16:03	9/15/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	10	31	M.d	33,364	31.33	1,065	190	1,627	D
9/17/25 16:03	9/15/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	10	31	S.d	-33,364	31.33	-1,065		1,627	D
9/17/25 16:02	9/15/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	2	5	M.d	910	14.30	64		16	D
9/17/25 09:45	9/15/25	CALC	Calcimedica, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	23	P.dm	241	2.49	97	4	2,476	I
9/16/25 21:45	9/12/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	M.dm	2,616	7.97	328	57	907	D
9/16/25 21:45	9/12/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	S.dm	-2,616	7.97	-328		907	D
9/16/25 21:21	9/10/25	BFRI	Biofrontera Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	M.d	0	0.00	225	999%	240	D
9/16/25 19:45	9/12/25	BYSI	Beyondspring Inc.		Health	Drug	Pharmaceutical Preparations	1	9	S.m	-1,415	2.81	-503		4,488	I
9/16/25 19:05	9/14/25	BTAI	Bioxcel Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	9	M.dm	0	0.00	7	1	538	D
9/16/25 18:54	8/12/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	10	M.dm	47,199	24.69	1,912	15	14,738	D
9/16/25 18:54	8/13/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	10	S.dm	-47,199	24.69	-1,912		14,738	D
9/16/25 18:16	8/15/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	5	24	M.dm	5,429	12.12	448	117	830	D
9/16/25 18:16	8/15/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	5	24	S.dm	-5,429	12.12	-448		830	D
9/16/25 18:09	9/12/25	LBRX	Lb Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	4	4	P.d	75,000	15.00	5,000	243	7,060	M
9/16/25 18:06	9/12/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	3	S.m	-1,025	25.63	-40		262	D
9/16/25 18:00	9/15/25	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	2	3	S	-678	25.03	-27		69	D
9/16/25 16:56	9/12/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	17	49	M.dm	58,401	48.71	1,199		1,125	D
9/16/25 16:56	9/12/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	17	49	S.dm	-58,401	48.71	-1,199		1,125	D
9/16/25 16:35	9/3/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	9	S	-19	6.12	-3		209	D
9/16/25 16:15	9/12/25	ZVRA	Zevra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	5	P.d	449	3.78	119	711	136	D
9/16/25 06:15	9/15/25	AARD	Aardvark Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	P.dm	379	7.12	53	2	3,123	D
9/15/25 20:12	9/11/25	CAMP	Camp4 Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	7	7	P	8,555	1.53	5,589	185	8,605	D
9/15/25 19:16	8/22/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	13	19	S.dm	-38,722	83.66	-463		1,904	D
9/15/25 17:39	9/12/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	23	M.dm	19,430	29.82	652	39	2,327	D
9/15/25 17:39	9/12/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	23	S.dm	-19,430	29.82	-652		2,327	D
9/15/25 16:47	9/9/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	4	18	M.d	2,168	36.81	59	11	587	D
9/15/25 16:47	9/9/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	4	18	S.d	-2,168	36.81	-59		587	D
9/15/25 16:26	9/11/25	MRSN	Mersana Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	M.d	15	1.69	9	976	10	D
9/15/25 16:26	9/12/25	MRSN	Mersana Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-15	1.69	-9		10	D
9/15/25 16:23	9/2/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	7	28	M.dm	81,696	81.71	1,000	285	1,351	D
9/15/25 16:23	9/2/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	7	28	S.dm	-81,696	81.71	-1,000		1,351	D
9/15/25 12:45	9/12/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	4	6	M.d	208	4.04	51	5	1,059	D
9/15/25 12:45	9/12/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	4	6	S.d	-208	4.04	-51		1,059	D
9/12/25 20:39	9/2/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	24	M.dm	9,867	37.26	265	30	1,160	D
9/12/25 20:39	9/2/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	24	S.dm	-9,867	37.26	-265		1,160	D
9/12/25 20:00	9/11/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	16	M.dm	8,344	28.88	289	248	405	D
9/12/25 20:00	9/11/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	16	S.dm	-8,344	28.88	-289		405	D
9/12/25 18:00	9/11/25	VTRS	Viatris Inc	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-292	10.05	-29		350	D
9/12/25 17:30	9/11/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	4	16	M.dm	2,161	5.00	432	44	1,413	D
9/12/25 17:30	9/11/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	4	16	S.dm	-2,161	5.00	-432		1,413	D
9/12/25 17:09	9/11/25	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	4	5	S.d	-1,863	7.31	-255		1,327	D
9/12/25 17:09	7/1/25	PMVP	Pmv Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	5	S	-1,052	1.64	-643		7,130	D
9/12/25 16:42	9/11/25	TGTX	Tg Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-672	32.24	-21		94	D
9/12/25 16:38	9/10/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	8	19	S.dm	-65,838	243.24	-271	0	67,974	D
9/12/25 16:38	9/10/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	8	19	M.dm	65,838	243.24	271	0	67,974	D
9/12/25 16:32	9/10/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	6	25	P.dm	10,715	8.77	1,222		1,117	D
9/12/25 16:30	9/10/25	XOMA	Xoma Royalty Corp	NV	Health	Drug	Pharmaceutical Preparations	2	2	M.d	51	4.57	11	48	34	D
9/12/25 16:11	9/12/25	RARE	Ultragenyx Pharmaceutical Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-169	34.20	-5		139	D
9/12/25 08:36	8/1/25	CPIX	Cumberland Pharmaceuticals Inc	TN	Health	Drug	Pharmaceutical Preparations	4	12	P.m	22	3.70	6	0	6,067	D
9/11/25 21:04	9/10/25	IMNM	Immunome Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	30	1.35	22	117	41	D
9/11/25 21:01	9/9/25	NKTR	Nektar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	3	8	S.dm	-939	37.29	-25		109	D
9/11/25 20:56	9/9/25	PAHC	Phibro Animal Health Corp	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.m	-857	40.59	-21		55	I
9/11/25 20:38	9/10/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	7	38	M.dm	17,909	46.87	382	14	3,079	D
9/11/25 20:38	9/10/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	7	38	S.dm	-17,909	46.87	-382		3,079	D
9/11/25 19:36	9/10/25	SMMT	Summit Therapeutics Inc.		Health	Drug	Pharmaceutical Preparations	2	2	P.m	11,970	17.69	677	0	1,183,663	I
9/11/25 18:57	9/9/25	LFVN	Lifevantage Corp		Health	Drug	Pharmaceutical Preparations	6	11	S.d	-86	0.2291	-376		1,451	M
9/11/25 18:00	8/22/25	DRRX	Durect Corp	DE	Health	Drug	Pharmaceutical Preparations	7	9	P.dm	921	1.50	614	15	4,722	D
9/11/25 18:00	9/9/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	14	M.dm	8,473	39.78	213	17	1,475	D
9/11/25 17:20	9/9/25	DNTH	Dianthus Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	1	2	M.d	869	21.72	40		0	D
9/11/25 17:20	9/9/25	DNTH	Dianthus Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-869	21.72	-40	-100	0	D
9/11/25 17:00	9/9/25	PRGO	Perrigo Co Plc	L2	Health	Drug	Pharmaceutical Preparations	7	9	M.d	1,400	25.01	56	29	249	D
9/11/25 16:16	9/10/25	BSPK	Bespoke Extracts, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	4	P.m	3	0.1600	17	1	2,512	D
9/11/25 16:05	9/9/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	8	12	M.dm	42,258	302.35	140	210	206	D
9/11/25 16:05	9/9/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	8	12	S.dm	-42,258	302.35	-140		206	D
9/10/25 20:12	9/8/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	17	S.dm	-1,965	18.90	-104		2,225	I
9/10/25 18:21	9/8/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	15	S.dm	-2,036	11.21	-182		1,613	D
9/10/25 17:00	9/8/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	10	M.dm	6,019	8.23	731	61	1,937	D
9/10/25 17:00	9/8/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	10	S.dm	-6,019	8.23	-731		1,937	D
9/10/25 15:09	9/5/25	CYCC	Cyclacel Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-217	8.41	-26		541	D
9/9/25 21:07	8/18/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	21	S.dm	-177,464	231.22	-768		4,029	D
9/9/25 19:02	9/6/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	24	M.d	1,556	8.08	193	39	682	D
9/9/25 19:02	9/8/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	24	S.d	-1,556	8.08	-193		682	D
9/9/25 18:37	9/7/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	2	9	M.d	465	8.22	57	39	202	D
9/9/25 18:37	9/8/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	2	9	S.d	-465	8.22	-57		202	D
9/9/25 16:40	9/5/25	PHAT	Phathom Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S	-20	9.16	-2		55	D
9/9/25 16:31	9/5/25	DYN	Dyne Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	S.m	-1,019	9.43	-108		457	D
9/9/25 16:28	9/8/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	P.m	713	7.13	100	17	680	D
9/9/25 16:26	9/5/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	14	31	S.d	-2,676	13.75	-195		503	D
9/9/25 16:14	9/6/25	IMNN	Imunon, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	0	0.00	2	77	4	D
9/9/25 16:02	9/5/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	3	5	P.d	912	7.27	125		20	D
9/8/25 19:06	9/4/25	AQST	Aquestive Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	M.d	487	3.83	127	28	574	D
9/8/25 19:06	9/4/25	AQST	Aquestive Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S.d	-487	3.83	-127		574	D
9/8/25 18:45	9/8/25	SNDX	Syndax Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	3	6	M.dm	5,668	12.92	439	304	583	D
9/8/25 18:45	9/8/25	SNDX	Syndax Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	3	6	S.dm	-5,668	12.92	-439		583	D
9/8/25 18:06	9/4/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	18	S.dm	-194,079	43.30	-4,483		26,998	I
9/8/25 17:37	9/4/25	PCRX	Pacira Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-180	24.81	-7		20	D
9/8/25 16:37	9/8/25	BHC	Bausch Health Companies Inc.	NJ	Health	Drug	Pharmaceutical Preparations	3	4	S.m	-333,977	8.79	-37,993		71,329	D
9/5/25 19:48	9/5/25	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-19	11.88	-2		30	D
9/5/25 18:00	9/4/25	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	5	8	M.d	60,311	140.62	429	162	694	D
9/5/25 18:00	9/4/25	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	5	8	S.d	-60,311	140.62	-429		694	D
9/5/25 17:46	9/4/25	PGEN	Precigen, Inc.	VA	Health	Drug	Pharmaceutical Preparations	1	3	P.dm	168	0.9993	168	335	218	D
9/5/25 17:01	9/3/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	2	8	S.dm	-40,165	11.42	-3,518		52,296	D
9/5/25 16:05	9/3/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	2	3	S.m	-31	16.51	-2		181	D
9/5/25 16:03	9/4/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	10	M.dm	4,715	17.76	266	4	7,364	D
9/5/25 16:03	9/4/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	10	S.dm	-4,715	17.76	-266		7,364	D
9/4/25 17:48	9/2/25	JAZZ	Jazz Pharmaceuticals Plc	L2	Health	Drug	Pharmaceutical Preparations	1	3	S	-993	124.07	-8		437	D
9/4/25 17:47	9/2/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	2	4	S	-311	131.40	-2		78	D
9/4/25 16:50	9/2/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	5	5	S	-368	12.05	-31		4,530	D
9/4/25 16:30	9/2/25	ANNX	Annexon, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	6	P	37	2.38	15	4	395	D
9/4/25 16:30	9/2/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	12	30	M.dm	12,691	43.39	292		205	D
9/4/25 16:30	9/2/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	12	30	S.dm	-12,691	43.39	-292		205	D
9/4/25 16:30	9/2/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	5	M.d	1,854	24.24	76	387	96	D
9/4/25 16:30	9/2/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	5	S.d	-1,854	24.24	-76		96	D
9/4/25 14:58	9/2/25	MTSR	Metsera, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-10	36.00	0	0	4,325	I
9/4/25 14:54	8/26/25	NATR	Natures Sunshine Products Inc	UT	Health	Drug	Pharmaceutical Preparations	4	4	S.m	-33,124	11.50	-2,879		260	D
9/4/25 14:29	7/23/25	DMAC	Diamedica Therapeutics Inc.	Z4	Health	Drug	Pharmaceutical Preparations	3	4	P.m	22,758	3.92	5,800	38	21,107	I
9/3/25 18:53	9/2/25	SYRE	Spyre Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-300	16.26	-18		98	D
9/3/25 18:46	9/2/25	BMY	Bristol Myers Squibb Co	DE	Health	Drug	Pharmaceutical Preparations	3	5	S.d	-2,667	44.89	-59		182	D
9/3/25 17:53	9/2/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	14	S.dm	-2,489	13.66	-182		238	D
9/3/25 16:56	8/29/25	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	5	9	S.d	-3,686	31.49	-117		3,504	D
9/3/25 16:20	9/2/25	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	1	3	S	-38	25.09	-2		78	D
9/3/25 06:04	8/28/25	SPRO	Spero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-16	1.97	-8		1,443	D
9/2/25 21:52	8/25/25	STTK	Shattuck Labs, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P.d	10,944	0.8677	12,612		2,102	I
8/29/25 20:35	8/27/25	CVKD	Cadrenal Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S.m	-98	13.99	-7		445	D
8/29/25 17:30	8/27/25	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	2	3	S.m	-3,688	55.15	-67		540	D
8/29/25 16:55	8/21/25	AKTX	Akari Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	1	3	P.m	39	1.04	37	14	299	D
8/29/25 16:02	8/27/25	VRTX	Vertex Pharmaceuticals Inc / Ma	MA	Health	Drug	Pharmaceutical Preparations	3	3	S	-5,947	389.56	-15		166	D
8/28/25 19:32	8/26/25	QTTB	Q32 Bio Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-32	1.80	-18		265	D
8/28/25 19:30	8/26/25	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	8	M.d	1,047	4.86	216	7	3,217	D
8/28/25 19:30	8/26/25	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	8	S.d	-1,047	4.86	-216		3,217	D
8/28/25 16:56	8/26/25	RLMD	Relmada Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	1	P.m	178	0.6696	266	36	1,000	D
8/28/25 16:55	8/26/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	14	M.d	1,729	6.51	266	97	538	D
8/28/25 16:55	8/26/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	14	S.d	-1,729	6.51	-266		538	D
8/28/25 16:25	8/27/25	AMRX	Amneal Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	5	9	S.dm	-10,845	8.45	-1,284		954	D
8/28/25 16:14	7/24/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	12	12	S.d	-231,475	797.67	-290	0	96,846	D
8/27/25 20:54	8/27/25	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	8	P.m	145	3.10	47	9	586	D
8/27/25 17:16	8/18/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	1	20	M.dm	624	3.13	199		0	D
8/27/25 17:16	8/18/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	1	20	S.dm	-624	3.13	-199	-100	0	D
8/26/25 21:54	8/25/25	DERM	Journey Medical Corp	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	81	0.0650	1,250	110	2,387	D
8/26/25 21:40	8/22/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	5	7	S.d	-2,818	9.89	-285		6,193	D
8/26/25 18:26	8/22/25	EOLS	Evolus, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-247	6.93	-36		179	D
8/26/25 17:17	7/10/25	ELTP	Elite Pharmaceuticals Inc /Nv/	NJ	Health	Drug	Pharmaceutical Preparations	3	5	P.d	538	0.0940	5,716	520	6,816	D
8/26/25 06:10	8/22/25	RNXT	Renovorx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P.m	9	0.9297	10	3	330	D
8/25/25 08:50	8/22/25	DVAX	Dynavax Technologies Corp	DE	Health	Drug	Pharmaceutical Preparations	2	2	P.m	22,393	10.82	2,069	15	15,761	D
8/22/25 19:07	8/21/25	SKYE	Skye Bioscience, Inc.	NV	Health	Drug	Pharmaceutical Preparations	2	2	S.m	-1,601	3.46	-463		19,364	I
8/22/25 16:30	8/21/25	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	7	S.dm	-15,575	17.40	-895		32,459	I
8/22/25 16:07	8/21/25	LYEL	Lyell Immunopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	S.m	-134	10.53	-13		124	D
8/21/25 20:44	8/21/25	CLNN	Clene Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-18	5.34	-3	0	705	D
8/21/25 17:22	8/21/25	TNXP	Tonix Pharmaceuticals Holding Corp.	NV	Health	Drug	Pharmaceutical Preparations	2	2	P	24	36.02	1		1	D
8/21/25 16:19	8/13/25	MGNX	Macrogenics Inc	DE	Health	Drug	Pharmaceutical Preparations	2	2	M.dm	151	0.9849	153	19	941	D
8/20/25 17:14	8/19/25	ETON	Eton Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.m	-674	16.15	-42		205	D
8/20/25 16:04	8/19/25	GOSS	Gossamer Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	50	1.92	26	81	58	D
8/20/25 16:02	8/18/25	ALXO	Alx Oncology Holdings Inc	DE	Health	Drug	Pharmaceutical Preparations	3	5	P	62	0.7590	82	28	377	D
8/20/25 16:01	8/15/25	ARCT	Arcturus Therapeutics Holdings Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	P	41	16.56	2	1	222	D
8/19/25 19:40	8/15/25	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	M.d	191	1.92	99	5	2,145	D
8/19/25 19:40	8/18/25	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	S.d	-191	1.92	-99		2,145	D
8/19/25 17:02	8/18/25	SEPN	Septerna, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	94	4.10	23	22	128	D
8/19/25 16:15	8/15/25	HRMY	Harmony Biosciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-787	36.50	-22	-100	0	D
8/19/25 16:08	8/15/25	MCRB	Seres Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	M.d	7	3.80	2	7	28	D
8/19/25 16:08	8/18/25	MCRB	Seres Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	S.d	-7	3.80	-2		28	D
8/19/25 16:01	8/18/25	COYA	Coya Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	19	1.09	18	176	28	D
8/18/25 18:00	8/14/25	ATAI	Atai Life Sciences N.V.	P7	Health	Drug	Pharmaceutical Preparations	1	1	P	19,000	2.19	8,676	20	52,845	I
8/18/25 16:33	8/15/25	EBS	Emergent Biosolutions Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-131	8.75	-15		209	D
8/15/25 16:30	8/14/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	10	S	-1,057	6.02	-176		2,599	D
8/15/25 16:09	8/13/25	ALDX	Aldeyra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P	127	5.17	25	12	224	D
8/14/25 17:00	8/12/25	ABBV	Abbvie Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	M.d	13,371	136.39	98	68	242	D
8/14/25 17:00	8/12/25	ABBV	Abbvie Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S.d	-13,371	136.39	-98		242	D
8/14/25 16:20	8/12/25	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.m	-246	8.21	-30		157	D
8/14/25 16:15	8/13/25	DSGN	Design Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-2,954	5.25	-563		3,655	I
8/14/25 16:01	8/13/25	MDCX	Medicus Pharma Ltd.	A6	Health	Drug	Pharmaceutical Preparations	1	1	M.d	156	1.08	145	38	528	D
8/13/25 18:00	8/11/25	LGVN	Longeveron Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P.d	0	0.00	24	8	303	D
8/13/25 16:08	8/11/25	ORGO	Organogenesis Holdings Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	10	2.47	4	1	672	D
8/13/25 16:05	8/7/25	BIVI	Biovie Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	1	P.d	0	0.00	5	100	10	I
8/13/25 16:05	8/11/25	IRWD	Ironwood Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	4	4	S	-11	0.8400	-13		1,101	D
8/13/25 13:58	8/11/25	ZOMDF	Zomedica Corp.	A0	Health	Drug	Pharmaceutical Preparations	1	3	P.m	82	0.0398	2,056	64	5,256	D
8/13/25 08:28	8/11/25	BBOT	Bridgebio Oncology Therapeutics, Inc.	E9	Health	Drug	Pharmaceutical Preparations	4	4	M.d	0	0.00	4,262	31	17,969	I
8/12/25 18:00	7/31/25	HRTX	Heron Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	5	8	M.d	6,231	1.47	4,233	12	38,713	D
8/12/25 16:05	8/11/25	OGN	Organon & Co.		Health	Drug	Pharmaceutical Preparations	1	1	M.d	0	0.00	12	87	25	D
8/12/25 07:00	8/8/25	ITRM	Iterum Therapeutics Plc	L2	Health	Drug	Pharmaceutical Preparations	1	1	P	11	0.7236	15	7	235	D
8/11/25 17:53	8/8/25	ABT	Abbott Laboratories	IL	Health	Drug	Pharmaceutical Preparations	1	1	S	-747	134.55	-6		51	D
8/11/25 16:35	8/11/25	RPRX	Royalty Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	1	1	S.d	-1,214	36.23	-34		195	D
8/8/25 16:56	8/8/25	OPK	Opko Health, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	891	1.32	675	0	248,373	I
8/8/25 16:05	8/7/25	VNDA	Vanda Pharmaceuticals Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	42	4.15	10	0	2,336	D
8/8/25 15:13	8/7/25	GOVX	Geovax Labs, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	1	0.6703	1	46	3	D
8/7/25 16:15	8/5/25	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	4	7	S.m	-149	0.9948	-150		8,360	D
8/6/25 20:38	8/6/25	VSTM	Verastem, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S.m	-120	5.17	-23		554	D
8/5/25 20:32	8/1/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	14	31	M.d	7,105	3.53	2,015	7	31,334	D
8/5/25 20:32	8/1/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	14	31	S.d	-7,105	3.53	-2,015		31,334	D
8/5/25 17:31	8/1/25	AUPH	Aurinia Pharmaceuticals Inc.		Health	Drug	Pharmaceutical Preparations	2	2	S.m	-13,800	10.45	-1,320		11,463	D
8/5/25 08:46	8/4/25	MRK	Merck & Co., Inc.	NJ	Health	Drug	Pharmaceutical Preparations	2	2	M.d	4,283	79.29	54	79	122	D
8/4/25 18:28	7/31/25	LRMR	Larimar Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	30,000	3.20	9,375	44	30,607	I
8/4/25 17:00	8/1/25	AMRN	Amarin Corp Plcuk	X0	Health	Drug	Pharmaceutical Preparations	2	2	M.d	0	0.00	75	802	85	D
8/4/25 16:43	8/3/25	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	1	1	M.d	0	0.00	2	1	205	D
8/4/25 09:00	7/31/25	ANIX	Anixa Biosciences Inc	DE	Health	Drug	Pharmaceutical Preparations	3	5	P	111	3.16	35	2	1,658	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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