Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	#o	#f	T	TVal	Price	Qty	oc	Own	H
2/10/26 21:46	2/6/26	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	6	6	M.d	29,663	174.17	170	57	471	D
2/10/26 21:10	2/6/26	ZNTL	Zentalis Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	5	6	S.m	-17,862	1.27	-14,015		20,269	D
2/10/26 19:11	2/10/26	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	13	M.dm	54,229	87.05	623	9	7,862	D
2/10/26 19:00	2/6/26	CING	Cingulate Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	P.d	167	5.04	33	32	138	I
2/10/26 18:27	2/7/26	ASRT	Assertio Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	M.d	0	0.00	5	14	39	D
2/10/26 18:17	2/7/26	MGNX	Macrogenics Inc	DE	Health	Drug	Pharmaceutical Preparations	7	7	M.dm	0	0.00	102	8	1,311	D
2/10/26 18:12	11/17/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	12	S.dm	-6,716	23.43	-287		2,327	I
2/10/26 18:00	11/17/25	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	3	6	M.d	502	8.10	62	258	86	D
2/10/26 18:00	11/18/25	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	3	6	S.d	-502	8.10	-62		86	D
2/10/26 17:04	2/6/26	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	14	44	S.d	-50,930	52.40	-972		899	D
2/10/26 16:49	2/3/26	ZVRA	Zevra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	15	S.dm	-1,224	1.94	-632		696	D
2/10/26 16:33	2/6/26	PRGO	Perrigo Co Plc	L2	Health	Drug	Pharmaceutical Preparations	2	2	M.d	153	14.32	11	17	75	D
2/10/26 16:32	2/6/26	ZTS	Zoetis Inc.		Health	Drug	Pharmaceutical Preparations	9	9	M.dm	0	0.00	18	14	153	D
2/10/26 16:30	2/3/26	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	10	90	S.dm	-341,029	312.30	-1,092		730	D
2/10/26 16:04	2/10/26	MRK	Merck & Co., Inc.	NJ	Health	Drug	Pharmaceutical Preparations	9	16	S.d	-57,681	111.34	-518		1,006	D
2/10/26 09:00	2/9/26	SNDX	Syndax Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.d	-628	20.90	-30		653	D
2/9/26 21:31	2/6/26	SPRO	Spero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.dm	-393	2.29	-172		1,861	D
2/9/26 19:47	1/30/26	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	14	M.d	1,342	7.34	183	525	217	D
2/9/26 19:47	1/30/26	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	14	S.d	-1,342	7.34	-183		217	D
2/9/26 18:28	2/5/26	MANE	Veradermics, Inc	DE	Health	Drug	Pharmaceutical Preparations	5	5	P.dm	54,092	19.02	2,844	64	7,279	M
2/9/26 16:25	12/16/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	7	33	S.dm	-6,740	3.95	-1,705		6,783	D
2/9/26 16:15	2/5/26	PAHC	Phibro Animal Health Corp	DE	Health	Drug	Pharmaceutical Preparations	1	15	S.dm	-10,422	44.87	-232		140	I
2/9/26 16:10	2/6/26	COCP	Cocrystal Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	6	P.m	200	0.9562	209	12	1,916	I
2/6/26 18:38	2/4/26	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	13	S.dm	-1,610	8.78	-183		493	D
2/6/26 16:57	2/4/26	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	4	13	M.dm	41,462	311.23	133	0	52,514	D
2/6/26 16:57	2/4/26	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	4	13	S.dm	-41,462	311.23	-133	0	52,514	D
2/6/26 16:38	2/6/26	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	5	13	M.dm	17,328	55.28	313	61	825	D
2/6/26 16:38	2/6/26	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	5	13	S.dm	-17,328	55.28	-313		825	D
2/6/26 16:18	2/3/26	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	9	34	S.dm	-69,463	125.69	-553		1,370	D
2/6/26 08:04	11/25/25	ABT	Abbott Laboratories	IL	Health	Drug	Pharmaceutical Preparations	3	3	S	-3,304	108.75	-30	0	7,239	D
2/5/26 20:17	2/5/26	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	8	28	M.d	14,038	37.09	379	103	746	D
2/5/26 20:17	2/5/26	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	8	28	S.d	-14,038	37.09	-379		746	D
2/5/26 19:00	2/3/26	PMN	Promis Neurosciences Inc.	Z4	Health	Drug	Pharmaceutical Preparations	1	1	P.d	8,500	12.13	701	289	943	I
2/5/26 17:42	1/27/26	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	6	16	M.d	14,867	14.11	1,054	14	8,626	I
2/5/26 16:48	2/3/26	ACRS	Aclaris Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	10	M.dm	0	0.00	416	27	1,967	D
2/5/26 16:24	2/3/26	CTNM	Contineum Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	7	S.d	-284	10.54	-27		171	D
2/5/26 16:14	2/3/26	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	28	M.d	2,824	20.48	138	4	3,608	D
2/5/26 16:10	2/4/26	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	6	15	S.dm	-584	8.75	-67		883	D
2/5/26 16:05	2/4/26	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	7	24	S.dm	-14,237	28.48	-500		1,052	D
2/5/26 10:18	2/3/26	CLNN	Clene Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	14	S.dm	-3,361	6.02	-559		1,274	I
2/4/26 21:33	2/2/26	SYRE	Spyre Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	3	S	-1,388	30.83	-45		687	D
2/4/26 21:15	2/2/26	MPLT	Maplight Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.m	-763	18.41	-41		397	D
2/4/26 20:35	11/24/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	9	21	M.dm	7,744	22.27	348	28	1,587	D
2/4/26 20:35	11/24/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	9	21	S.dm	-7,744	22.27	-348		1,587	D
2/4/26 20:23	2/2/26	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	5	5	S.m	-437	11.10	-39		4,551	D
2/4/26 20:12	2/3/26	TNGX	Tango Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S.d	-727	12.26	-59		2,001	D
2/4/26 19:43	12/5/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	13	M.dm	32,706	41.63	786	6	13,857	D
2/4/26 19:43	12/5/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	13	S.dm	-32,706	41.63	-786		13,857	D
2/4/26 19:37	2/3/26	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	6	8	S.d	-395	9.71	-41		155	D
2/4/26 18:24	12/15/25	KNSA	Kiniksa Pharmaceuticals International, Plc		Health	Drug	Pharmaceutical Preparations	4	16	M.dm	7,347	29.66	248		86	D
2/4/26 18:24	12/15/25	KNSA	Kiniksa Pharmaceuticals International, Plc		Health	Drug	Pharmaceutical Preparations	4	16	S.dm	-7,347	29.66	-248		86	D
2/4/26 17:31	2/3/26	IGC	Igc Pharma, Inc.	MD	Health	Drug	Pharmaceutical Preparations	2	2	M.d	0	0.00	150	7	2,232	I
2/4/26 17:18	2/2/26	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	3	6	S.d	-917	120.32	-8		201	D
2/4/26 17:09	1/1/26	PCSA	Processa Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	M.d	0	0.00	1	4	18	D
2/4/26 17:07	1/30/26	RPRX	Royalty Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	3	20	S.m	-50,051	39.73	-1,260		2,057	I
2/4/26 16:32	12/5/25	BOLT	Bolt Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	P.d	1	4.61	0	7	4	D
2/4/26 16:30	2/2/26	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	9	12	S	-1,248	5.21	-239		3,426	D
2/4/26 16:25	2/3/26	CRBP	Corbus Pharmaceuticals Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-390	10.92	-36		2,493	D
2/4/26 16:25	2/2/26	LXRX	Lexicon Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	P	2,000	1.30	1,538	4	44,145	I
2/4/26 16:20	1/26/26	RIGL	Rigel Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	2	2	M.d	2,332	26.96	87	41	300	D
2/4/26 16:15	2/2/26	ALXO	Alx Oncology Holdings Inc	DE	Health	Drug	Pharmaceutical Preparations	2	2	P	5,004	1.57	3,189	32	13,140	I
2/4/26 16:15	2/2/26	AKBA	Akebia Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	6	S	-901	1.39	-648		6,528	D
2/4/26 16:15	12/8/25	FULC	Fulcrum Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	S	-59,089	13.94	-4,239		6,549	I
2/4/26 16:11	2/3/26	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S	-12	6.27	-2		108	D
2/4/26 16:05	2/2/26	SLGL	Sol-Gel Technologies Ltd.	L3	Health	Drug	Pharmaceutical Preparations	1	12	P.m	3,857	41.71	92	25	461	I
2/4/26 16:05	2/2/26	GBIO	Generation Bio Co.		Health	Drug	Pharmaceutical Preparations	3	7	M.d	0	0.00	5	3	194	D
2/4/26 16:05	2/2/26	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	13	S.dm	-7,745	10.36	-748		7,446	D
2/3/26 21:45	1/31/26	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	38	M.d	26,194	45.51	576	14	4,763	D
2/3/26 21:45	2/2/26	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	38	S.d	-26,194	45.51	-576		4,763	D
2/3/26 19:53	1/31/26	AVIR	Atea Pharmaceuticals, Inc.	MA	Health	Drug	Pharmaceutical Preparations	6	6	M.dm	372	0.4533	821	12	7,866	D
2/3/26 19:00	1/31/26	AMRN	Amarin Corp Plcuk	X0	Health	Drug	Pharmaceutical Preparations	5	8	M.d	0	0.00	28	25	144	D
2/3/26 18:59	1/30/26	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	3	8	S.dm	-3,339	21.27	-157		433	D
2/3/26 18:24	2/2/26	PCRX	Pacira Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	6	S.dm	-1,521	20.97	-73		425	D
2/3/26 16:40	2/1/26	BMY	Bristol Myers Squibb Co	DE	Health	Drug	Pharmaceutical Preparations	2	2	M.d	0	0.00	13	53	36	D
2/3/26 16:32	2/1/26	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	10	24	M.ed	2,191	1.71	1,283	1	94,190	D
2/3/26 16:30	2/2/26	ZBIO	Zenas Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	P.m	2,663	16.96	157	8	2,132	D
2/3/26 16:26	1/13/26	BIOA	Bioage Labs, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	13	S.d	-6,638	13.34	-498		1,006	D
2/3/26 16:15	1/27/26	ALT	Altimmune, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	14	M.dm	127	0.5576	228	55	643	D
2/3/26 16:05	12/10/25	AVBP	Arrivent Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-12,983	23.37	-556		3,929	I
2/3/26 12:35	11/24/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	1	32	M.dm	248	1.60	155		6	D
2/3/26 12:35	11/24/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	1	32	S.dm	-248	1.60	-155		6	D
2/3/26 12:00	2/2/26	RARE	Ultragenyx Pharmaceutical Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	S	-259	27.63	-9		146	D
2/3/26 08:30	1/31/26	HRTX	Heron Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	3	6	M.d	0	0.00	80	9	949	D
2/2/26 20:52	2/2/26	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	2	10	M.d	5,115	31.59	162	999%	169	D
2/2/26 20:52	2/2/26	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	2	10	S.d	-5,115	31.59	-162		169	D
2/2/26 18:11	1/8/26	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	5	10	S.dm	-2,217	4.91	-452		6,669	D
2/2/26 16:30	11/24/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	26	S.dm	-89,437	82.63	-1,082		19,525	I
2/2/26 16:08	1/30/26	APRE	Aprea Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	P.d	61	1.01	60	10	666	D
1/30/26 18:39	1/28/26	CRVS	Corvus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	1,119	5.33	210	2	8,819	D
1/29/26 20:05	1/29/26	SRPT	Sarepta Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	M.d	582	17.03	34	9	432	D
1/29/26 19:32	1/28/26	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	1	2	S.m	-102	2.16	-47		1,036	D
1/29/26 16:40	1/27/26	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	4	12	M.dm	17,628	21.89	805		642	D
1/29/26 16:40	1/27/26	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	4	12	S.dm	-17,628	21.89	-805		642	D
1/29/26 16:05	1/22/26	ORMP	Oramed Pharmaceuticals Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	M.d	0	0.00	166	3	6,518	D
1/29/26 08:58	1/28/26	ANIX	Anixa Biosciences Inc	DE	Health	Drug	Pharmaceutical Preparations	2	2	P.d	77	2.97	26	2	1,104	D
1/28/26 20:19	1/24/26	HRMY	Harmony Biosciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	11	M.dm	3,588	22.99	156		35	D
1/28/26 18:30	12/15/25	MIST	Milestone Pharmaceuticals Inc.	A8	Health	Drug	Pharmaceutical Preparations	5	11	S.dm	-1,094	1.73	-634		951	D
1/28/26 18:30	1/26/26	MIST	Milestone Pharmaceuticals Inc.	A8	Health	Drug	Pharmaceutical Preparations	5	11	M.dm	1,094	1.73	634	200	951	D
1/28/26 16:30	1/26/26	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	8	30	S.d	-9,383	18.04	-520		4,436	D
1/28/26 16:05	1/27/26	SIGA	Siga Technologies Inc	DE	Health	Drug	Pharmaceutical Preparations	1	1	M.d	0	0.00	56	125	101	D
1/27/26 21:35	1/27/26	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	15	S.d	-1,345	8.44	-159		1,034	D
1/26/26 18:02	1/26/26	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	25	M.d	61,603	233.73	264	14	2,158	D
1/26/26 16:34	11/24/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	19	M.dm	2,773	9.81	283	60	754	D
1/26/26 16:34	11/24/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	19	S.dm	-2,773	9.81	-283		754	D
1/26/26 16:01	1/23/26	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	2	5	M.dm	5,577	14.02	398	121	725	D
1/23/26 17:34	1/21/26	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	13	S	-4,226	72.36	-58		887	D
1/23/26 16:05	1/21/26	PVLA	Palvella Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	6	M.d	1,311	50.78	26		0	D
1/23/26 16:05	1/21/26	PVLA	Palvella Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	6	S.d	-1,311	50.78	-26	-100	0	D
1/23/26 13:34	1/21/26	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	M.d	3,570	15.46	231		20	D
1/23/26 13:34	1/21/26	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-3,570	15.46	-231		20	D
1/22/26 21:46	1/20/26	PLRX	Pliant Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	S	-164	1.28	-128		1,295	D
1/22/26 21:30	1/21/26	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	15	S.d	-3,587	8.18	-439		726	D
1/22/26 20:09	12/26/25	COGT	Cogent Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	5	S.d	-139,579	36.59	-3,815		6,019	D
1/22/26 19:31	1/20/26	NKTR	Nektar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	3	4	S.d	-355	45.13	-8		97	D
1/22/26 19:26	1/20/26	FOLD	Amicus Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	15	M.dm	7,171	9.55	751	46	2,396	D
1/22/26 19:26	1/20/26	FOLD	Amicus Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	15	S.dm	-7,171	9.55	-751		2,396	D
1/22/26 19:00	1/20/26	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	10	S.d	-2,023	26.05	-78		1,564	M
1/22/26 13:04	12/12/25	OGEN	Oragenics Inc	FL	Health	Drug	Pharmaceutical Preparations	1	2	S.d	0	0.9429	0		35	D
1/22/26 07:00	1/21/26	RNXT	Renovorx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	8	P.m	65	0.8748	74	7	1,139	D
1/21/26 21:00	12/19/25	OLMA	Olema Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	12	M.dm	26,882	19.82	1,356	183	2,099	D
1/21/26 21:00	12/19/25	OLMA	Olema Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	12	S.dm	-26,882	19.82	-1,356		2,099	D
1/21/26 18:55	12/17/25	IRON	Disc Medicine, Inc.		Health	Drug	Pharmaceutical Preparations	4	12	S.dm	-23,059	73.11	-315		315	I
1/21/26 17:17	1/20/26	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	S	-233	3.65	-64		2,324	D
1/21/26 16:04	12/15/25	SPRB	Spruce Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	5	M.dm	0	0.00	13	131	24	D
1/21/26 12:46	1/21/26	XCUR	Exicure, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	S	-11,579	5.34	-2,168		5,925	D
1/21/26 09:09	1/16/26	IMRX	Immuneering Corp	DE	Health	Drug	Pharmaceutical Preparations	5	5	P	234	4.52	52	3	1,649	D
1/20/26 20:33	11/20/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	12	S.dm	-57,658	35.79	-1,611		8,630	I
1/20/26 19:19	12/15/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	9	M.d	677	3.09	219	26	1,057	D
1/20/26 19:19	12/16/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	9	S.d	-677	3.09	-219		1,057	D
1/20/26 17:39	1/15/26	NKTX	Nkarta, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-66	2.07	-32		558	D
1/20/26 16:33	1/15/26	DVAX	Dynavax Technologies Corp	DE	Health	Drug	Pharmaceutical Preparations	5	8	M.dm	3,609	7.18	503	653	580	D
1/20/26 16:33	1/15/26	DVAX	Dynavax Technologies Corp	DE	Health	Drug	Pharmaceutical Preparations	5	8	S.dm	-3,609	7.18	-503		580	D
1/20/26 16:30	1/16/26	ONCY	Oncolytics Biotech Inc		Health	Drug	Pharmaceutical Preparations	1	1	P	104	1.04	100	27	467	D
1/20/26 16:30	1/12/26	TYRA	Tyra Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	6	S.m	-9,798	18.49	-530		4,130	D
1/20/26 16:07	12/2/25	HOWL	Werewolf Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	24	S.m	-2,892	0.8751	-3,305		14,479	I
1/20/26 10:29	10/17/25	MYNZ	Mainz Biomed N.V.	P7	Health	Drug	Pharmaceutical Preparations	1	2	P.e	1,436	1.08	1,329		685	D
1/16/26 17:26	1/15/26	ORKA	Oruka Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	6	M.d	949	20.64	46	29	207	D
1/16/26 17:26	1/15/26	ORKA	Oruka Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	6	S.d	-949	20.64	-46		207	D
1/16/26 17:22	1/2/26	TERN	Terns Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	5	S.dm	-5,730	15.02	-382		348	D
1/16/26 17:00	1/10/26	ELDN	Eledon Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	6	M.d	0	0.00	26		26	D
1/16/26 16:02	1/14/26	ACRV	Acrivon Therapeutics, Inc.		Health	Drug	Pharmaceutical Preparations	3	3	P	114	1.69	68	3	2,507	D
1/16/26 13:05	12/23/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	6	37	S.dm	-7,935	22.36	-355		576	D
1/15/26 16:45	1/13/26	PHAT	Phathom Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	M.d	180	1.68	108	101	214	D
1/15/26 14:35	1/2/26	ACUR	Acura Pharmaceuticals, Inc	NY	Health	Drug	Pharmaceutical Preparations	3	3	M.d	0	0.00	150	4	3,776	D
1/15/26 06:05	1/13/26	GLSI	Greenwich Lifesciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	6	P	379	18.38	21	0	5,604	D
1/14/26 21:00	12/11/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	8	23	M.dm	579,179	17.18	33,717	32	139,172	D
1/14/26 21:00	12/11/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	8	23	S.dm	-579,179	17.18	-33,717		139,172	D
1/14/26 18:20	1/12/26	AKTS	Aktis Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	6	P.d	114,312	18.00	6,351	33	25,418	I
1/14/26 18:14	12/18/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	5	6	S.m	-2,420	87.37	-28		450	D
1/14/26 17:25	1/12/26	OMER	Omeros Corp	WA	Health	Drug	Pharmaceutical Preparations	1	2	S.dm	-843	9.36	-90	-100	0	D
1/14/26 17:25	1/13/26	OMER	Omeros Corp	WA	Health	Drug	Pharmaceutical Preparations	1	2	M.dm	843	9.36	90		0	D
1/14/26 16:26	1/12/26	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	2	4	M.d	1,179	20.99	56		53	D
1/14/26 16:26	1/12/26	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	2	4	S.d	-1,179	20.99	-56		53	D
1/14/26 16:23	1/12/26	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	5	10	S.dm	-28,550	299.07	-95		211	D
1/13/26 18:20	1/9/26	ALMS	Alumis Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	16	P.m	50,952	10.55	4,829	10	53,679	I
1/13/26 17:11	1/12/26	ZYME	Zymeworks Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	16	M.d	4,674	8.11	576		435	D
1/13/26 17:11	1/12/26	ZYME	Zymeworks Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	16	S.d	-4,674	8.11	-576		435	D
1/13/26 16:35	1/9/26	ELTP	Elite Pharmaceuticals Inc /Nv/	NJ	Health	Drug	Pharmaceutical Preparations	1	1	M.d	75	0.0300	2,500	71	6,000	D
1/12/26 21:01	1/8/26	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	13	S.dm	-27,260	51.69	-527		6,250	I
1/12/26 16:09	1/9/26	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	6	M.d	2,006	27.77	72	52	211	D
1/12/26 08:44	9/19/22	MAIA	Maia Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	14	P.dm	530	1.15	461	12	4,410	I
1/9/26 20:30	1/8/26	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	4	10	S.dm	-4,123	5.20	-793		4,787	D
1/9/26 18:59	1/8/26	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	8	M.d	851	4.68	182	7	2,818	D
1/9/26 18:59	1/8/26	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	8	S.d	-851	4.68	-182		2,818	D
1/9/26 17:37	1/8/26	EQ	Equillium, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	5	S.dm	-292	1.17	-250		127	D
1/9/26 16:05	1/7/26	VRTX	Vertex Pharmaceuticals Inc / Ma	MA	Health	Drug	Pharmaceutical Preparations	5	11	S.dm	-90,942	285.03	-319		141	D
1/8/26 21:20	1/7/26	ERAS	Erasca, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	M.d	875	3.65	240		25	D
1/8/26 21:20	1/7/26	ERAS	Erasca, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-875	3.65	-240		25	D
1/8/26 20:27	1/6/26	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S.m	-322	5.86	-55		7,495	D
1/8/26 16:20	1/6/26	RNAC	Cartesian Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	6	S.d	-514	6.20	-83		628	D
1/8/26 16:05	11/25/25	CVRX	Cvrx, Inc.	NJ	Health	Drug	Pharmaceutical Preparations	1	4	S.m	-325	10.03	-32		4,050	I
1/8/26 16:05	1/6/26	HROW	Harrow, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S.d	-2,015	7.75	-260		7,682	I
1/8/26 16:03	1/7/26	REGN	Regeneron Pharmaceuticals, Inc.	NY	Health	Drug	Pharmaceutical Preparations	5	10	M.d	192,991	476.69	405	27	1,890	D
1/8/26 16:03	1/7/26	REGN	Regeneron Pharmaceuticals, Inc.	NY	Health	Drug	Pharmaceutical Preparations	5	10	S.d	-192,991	476.69	-405		1,890	D
1/7/26 21:34	11/13/25	BHVN	Biohaven Ltd.	D8	Health	Drug	Pharmaceutical Preparations	7	9	P.d	33,145	7.45	4,446	38	16,166	D
1/7/26 20:15	1/5/26	ANTX	An2 Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	S.m	-50	1.01	-49		363	D
1/7/26 17:11	1/5/26	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	6	M.d	1,169	15.03	78	5	1,528	D
1/7/26 17:11	1/5/26	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	6	S.d	-1,169	15.03	-78		1,528	D
1/7/26 16:55	1/5/26	CLYM	Climb Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	P.dm	780	2.42	322	3	11,301	I
1/7/26 16:23	1/5/26	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	14	M.d	914	8.75	104	46	329	D
1/7/26 16:23	1/5/26	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	14	S.d	-914	8.75	-104		329	D
1/7/26 16:15	12/16/25	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	14	S.dm	-7,238	22.42	-323		4,097	D
1/7/26 16:05	1/5/26	IRWD	Ironwood Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-183	4.41	-41		512	D
1/7/26 13:51	1/5/26	INDV	Indivior Plc	X0	Health	Drug	Pharmaceutical Preparations	5	5	P	172	35.39	5	10	56	D
1/7/26 12:45	1/5/26	ACTU	Actuate Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-1,624	5.80	-280		2,354	I
1/6/26 21:30	12/11/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	10	19	P.dm	48,255	13.69	3,526	11	36,993	I
1/6/26 20:22	1/2/26	ATAI	Ataibeckley Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-154	3.90	-40		7,663	D
1/6/26 20:00	1/2/26	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	6	6	S.dm	-328	6.63	-50		1,169	D
1/6/26 17:00	1/5/26	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	11	36	M.d	1,948	5.98	326	5	6,869	D
1/6/26 16:30	1/2/26	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	M.d	23	6.65	4	88	7	D
1/6/26 16:30	1/2/26	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	S.d	-23	6.65	-4		7	D
1/6/26 16:05	1/2/26	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	5	P	69	3.20	22	1	1,983	D
1/6/26 16:02	12/24/25	LYEL	Lyell Immunopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.m	-74	35.80	-2		7	D
1/5/26 21:50	1/5/26	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	14	S.dm	-33,921	60.30	-563		4,874	D
1/5/26 20:31	1/5/26	VKTX	Viking Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	5	S.d	-12,105	31.80	-381		3,234	D
1/5/26 16:30	1/1/26	XLO	Xilio Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	6	M.d	6	0.0605	94	32	390	D
1/5/26 16:16	12/8/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	17	S.dm	-4,121	19.50	-211		489	D
1/5/26 16:15	1/2/26	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-8	0.8553	-9		398	D
1/5/26 15:46	12/31/25	MNPR	Monopar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	4	4	M.d	449	22.82	20	5	419	D
1/5/26 08:00	12/31/25	HYPD	Hyperion Defi, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	5	P.m	611	3.23	189	37	698	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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