Pharmaceutical Preparations Industry - Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	Owner	oSt	Rel	Title	#f	T	TVal	Price	Qty	oc	Own	H
1/13/26 20:43	11/11/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Congleton Jon	PA	DO	CEO	7	S	-11,052	37.32	-296		896	D
1/13/26 20:43	11/11/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Levy Adam Scott	PA	O	CFO,Secr	8	S.dm	-7,768	30.14	-258		237	D
1/13/26 20:43	10/15/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rodman David Malcom	PA	O	Chief Me	12	S.dm	-12,549	28.77	-436		141	D
1/13/26 18:53	9/9/25	PAHC	Phibro Animal Health Corp	DE	Health	Drug	Pharmaceutical Preparations	Bendheim Jack	NJ	DOT	P,CEO	18	S.dm	-9,593	42.48	-226		91	I
1/13/26 17:54	1/9/26	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Patel Anish	CO	O	COO	14	S.d	-3,505	23.26	-151		343	I
1/13/26 17:37	1/9/26	RPRX	Royalty Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Urist Marshall	NY	O	EVP,Rese	7	S	-7,193	39.27	-183		228	I
1/13/26 17:11	1/12/26	ZYME	Zymeworks Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hollywood Mark	DE	O	EVP,COO	1	S.d	-139	22.67	-6		133	D
1/13/26 17:10	1/12/26	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Benkowitz Michael	MD	O	P,COO	41	S.dm	-280,967	425.54	-660	-100	3	I
1/13/26 16:47	1/9/26	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Friedman Paul A	PA	D		7	S.dm	-101,803	397.89	-256		843	D
1/13/26 16:38	1/9/26	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Taub Rebecca	PA	D		8	S.dm	-47,863	411.90	-116		1,117	D
1/13/26 16:36	1/12/26	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Krepp Sarah	NC	O	Chief Hu	5	S.d	-584	32.50	-18		143	D
1/13/26 16:36	1/12/26	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Moomaw Scott	NC	O	Chief Co	13	S.d	-3,307	26.68	-124		225	D
1/13/26 16:34	1/12/26	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Kaseta Michael	NC	O	CFO,COO	15	S.d	-3,747	22.48	-167		412	D
1/13/26 16:34	1/12/26	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Adair Jason	NC	O	Chief Bu	20	S.dm	-2,689	27.21	-99		194	D
1/13/26 16:33	1/12/26	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Schundler Russell	NC	O	GC	13	S.d	-1,877	22.86	-82		597	D
1/13/26 16:33	9/2/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Jeffs Roger	NC	DO	CEO	11	S.dm	-17,984	57.52	-313		2,764	D
1/13/26 16:31	1/12/26	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Boyle Dana	NC	O	Chief Ac	8	S.d	-1,251	27.66	-45		187	D
1/13/26 16:31	1/12/26	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	Saggar Rajeev	NC	O	Chief Me	13	S.d	-3,885	25.40	-153		273	D
1/13/26 16:04	12/18/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Lewis William	NJ	DO	Chair,CE	25	S.dm	-54,726	90.19	-607		738	D
1/13/26 16:03	1/9/26	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Flammer Martina M.D.	NJ	O	Chief Me	17	S.dm	-66,851	109.86	-609		138	D
1/12/26 21:01	9/4/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kumar Neil	CA	DO	CEO	17	S.dm	-72,571	44.59	-1,627		6,906	I
1/12/26 21:00	1/12/26	ZYME	Zymeworks Inc.	DE	Health	Drug	Pharmaceutical Preparations	Smith Jeffrey T L	DE	O	EVP,Chie	3	S.d	-641	20.72	-31		27	D
1/12/26 20:32	1/12/26	ZYME	Zymeworks Inc.	DE	Health	Drug	Pharmaceutical Preparations	Moore Paul Andrew	DE	O	Chief Sc	3	S.d	-1,038	20.40	-51		48	D
1/12/26 19:07	1/12/26	ZYME	Zymeworks Inc.	DE	Health	Drug	Pharmaceutical Preparations	Galbraith Kenneth	DE	DO	Chair,CE	4	S.d	-4,193	22.12	-190		227	D
1/12/26 17:12	1/8/26	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lyssikatos Joseph P	CO	O	CHIEF SC	20	S.m	-7,906	24.34	-325		1,078	I
1/12/26 17:11	1/8/26	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Heyman Richard A.	CO	D		6	S.m	-551	25.78	-21		194	I
1/12/26 17:09	3/27/25	HOWL	Werewolf Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Evnin Luke	MA	D		17	S.dm	-1,998	0.9977	-2,002		4,310	I
1/12/26 16:38	1/8/26	CLNN	Clene Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ugwumba Chidozie	AR	T		7	S.dm	-2,370	6.46	-367		796	I
1/12/26 16:21	1/9/26	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	Kaye Jack	P7	D		3	S.d	-1,382	29.22	-47		20	D
1/12/26 16:10	8/5/25	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	Taiwan Carbon Nano Technology Corp	F5	T		7	S.m	-170	1.93	-88		5,471	D
1/9/26 20:30	1/8/26	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	Tross Stuart A	CT	O	Chief Pe	5	S	-1,615	6.36	-254		1,047	D
1/9/26 19:34	1/7/26	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	Davidson Michael H.	P7	DO	CEO	2	S.d	0	0.00	-24		460	D
1/9/26 19:16	1/8/26	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Lizzul Paul F.	CA	O	Chief Me	6	S.d	-666	43.46	-15		42	D
1/9/26 19:14	9/16/24	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Mulroy Dennis	CA	O	CFO	6	S.d	-2,037	44.54	-46		22	D
1/9/26 19:13	9/16/24	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Loumeau Eric J	CA	O	GC	7	S.dm	-2,936	43.04	-68		13	D
1/9/26 19:12	1/8/26	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	Faga Daniel	CA	DO	P,CEO	3	S.d	-1,716	44.23	-39		479	D
1/9/26 18:59	1/8/26	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Williams Laura A	MA	O	Chief Pa	7	S.d	-1,001	6.20	-161		403	D
1/9/26 17:37	1/8/26	EQ	Equillium, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tom Penny	CA	O	Principa	3	S.dm	-46	0.9377	-49		10	D
1/9/26 17:34	1/8/26	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	McCulloch Kevin	IL	O	See Rema	1	S	-120	8.00	-15		1,710	D
1/9/26 17:15	1/7/26	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	Lee Chan Henry	V8	O	SVP,GC	12	S.dm	-12,585	317.29	-40		278	D
1/9/26 17:13	1/7/26	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Boyce Sarah	CA	DO	P,CEO	7	S.d	-8,116	42.66	-190		337	D
1/9/26 17:13	1/7/26	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Calderaro Charles III	CA	O	Chief Te	1	S	-269	72.23	-4		50	D
1/9/26 17:13	1/7/26	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McCarthy Teresa	CA	O	CHRO	12	S.d	-7,584	41.67	-182		117	D
1/9/26 17:12	1/7/26	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Moriarty John B	CA	O	GC	2	S	-253	54.72	-5		75	D
1/9/26 17:12	1/7/26	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Maclean Michael F	CA	O	CFO	7	S.d	-7,518	43.44	-173		121	D
1/9/26 17:12	1/7/26	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hughes Steven George	CA	O	Chief Me	9	S.d	-4,501	42.05	-107		82	D
1/9/26 17:12	1/7/26	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Flanagan W. Michael	CA	O	Chief Sc	11	S.d	-12,588	39.90	-315		92	D
1/9/26 17:08	1/7/26	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Devers Shannon L.	CA	O	EVP,Chie	5	S.dm	-5,981	79.05	-76		17	D
1/9/26 16:53	1/7/26	MIST	Milestone Pharmaceuticals Inc.	A8	Health	Drug	Pharmaceutical Preparations	Oliveto Joseph	A8	DO	P,CEO	1	S.m	-98	2.25	-44		304	D
1/9/26 16:35	1/8/26	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	Ragosa Mark	X0	O	CFO	12	S.dm	-9,159	28.98	-316		31	D
1/9/26 16:05	1/7/26	VRTX	Vertex Pharmaceuticals Inc / Ma	MA	Health	Drug	Pharmaceutical Preparations	Tatsis Ourania	MA	O	EVP,Chie	8	S	-8,429	475.21	-18		68	D
1/9/26 12:27	8/18/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	Moreadith Randall	AL	O	Chief Sc	28	S.dm	-925	5.08	-182		6	D
1/8/26 21:20	1/7/26	ERAS	Erasca, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Garner Ebun	CA	O	GC,Corp.	1	S.d	-671	5.59	-120		25	D
1/8/26 20:42	1/7/26	XCUR	Exicure, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Exicure Hitron Inc.	MA	T		1	S	-3,336	4.50	-741		5,925	D
1/8/26 20:35	1/6/26	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	Guyer William	CA	O	Chief De	19	S.dm	-17,559	67.80	-259		6	D
1/8/26 20:27	1/6/26	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Auerbach Alan H	CA	DOT	P,CEO	3	S.m	-478	4.12	-116		7,181	D
1/8/26 20:15	1/6/26	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hunt Douglas M	CA	O	See Rema	3	S.m	-108	4.23	-25		165	D
1/8/26 20:14	1/6/26	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Nougues Maximo F	CA	O	CFO	3	S.m	-130	4.24	-31		204	D
1/8/26 17:23	1/8/26	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	Hopkinson Craig C.	MA	O	EVP R,D,	13	S.dm	-20,909	32.71	-639		99	D
1/8/26 17:22	1/6/26	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Adsett Roger	NJ	O	COO	9	S.dm	-13,532	89.85	-151		189	D
1/8/26 17:21	7/21/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Bonstein Sara	NJ	O	CFO	11	S.dm	-29,817	93.34	-319		156	D
1/8/26 17:19	1/6/26	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Smith Michael Alexander	NJ	O	GC	11	S.dm	-15,582	109.03	-143		97	D
1/8/26 16:20	1/6/26	RNAC	Cartesian Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Brunn Carsten	MD	DO	P,CEO	2	S.m	-452	11.01	-41		324	D
1/8/26 16:19	1/6/26	RNAC	Cartesian Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Miljkovic Milos	MD	O	Chief Me	3	S.dm	-963	15.94	-60		59	D
1/8/26 16:19	1/6/26	RNAC	Cartesian Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Davis Blaine	MD	O	CFO	2	S.m	-206	11.10	-19		121	D
1/8/26 16:05	11/25/25	CVRX	Cvrx, Inc.	NJ	Health	Drug	Pharmaceutical Preparations	Johnson & Johnson	NJ	T		5	S.m	-861	10.14	-85		4,051	I
1/8/26 16:05	6/9/25	HROW	Harrow, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Opaleye Management Inc.	MA	T		10	S.m	-3,975	34.57	-115		3,960	I
1/8/26 16:05	1/6/26	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Frates James M	MA	O	CFO	3	S	-229	9.26	-25		318	D
1/8/26 16:05	1/6/26	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Cohen Joshua B	MA	DO	Co-CEO	7	S	-735	7.23	-102		3,355	D
1/8/26 16:05	1/6/26	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Klee Justin B.	MA	DO	Co-CEO	7	S	-736	7.24	-102		3,355	D
1/8/26 16:04	1/6/26	VRTX	Vertex Pharmaceuticals Inc / Ma	MA	Health	Drug	Pharmaceutical Preparations	Wagner Charles F Jr	MA	O	EVP,CO,F	4	S.d	-13,982	468.72	-30		52	D
1/8/26 16:03	1/7/26	REGN	Regeneron Pharmaceuticals, Inc.	NY	Health	Drug	Pharmaceutical Preparations	Bassler Bonnie L	NY	D		2	S.d	-1,770	783.19	-2		2	D
1/8/26 16:00	7/24/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	Lilly Endowment Inc	IN	T		45	S.e	-3,043,512	606.39	-5,019		96,892	D
1/7/26 20:15	1/5/26	ANTX	An2 Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Day Lucy	CA	O	CFO	2	S.m	-13	1.09	-12		75	D
1/7/26 20:15	1/5/26	ANTX	An2 Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Prior Stephen David	CA	O	Chief St	3	S.m	-10	1.09	-9		66	D
1/7/26 20:13	1/5/26	ANTX	An2 Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chanda Sanjay	CA	O	Chief De	2	S.m	-13	1.09	-12		76	D
1/7/26 20:12	1/5/26	ANTX	An2 Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Eizen Joshua M	CA	O	See Rema	3	S.m	-41	1.10	-37		177	D
1/7/26 19:00	1/5/26	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Tabuteau Herriot	NY	DOT	CEO	5	S.dm	-70,126	142.65	-492		7,352	D
1/7/26 18:31	1/5/26	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	Kastelein Johannes Jacob Pieter	P7	DO	Chief Sc	2	S.dm	-2,671	25.20	-106		99	D
1/7/26 18:27	1/5/26	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	Kooij Louise Frederika	P7	O	Chief Ac	7	S.dm	-13,581	26.17	-519		24	D
1/7/26 18:27	1/5/26	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	Somaiya Mayur Ian	P7	O	CFO	2	S.dm	-170	2.54	-67		58	D
1/7/26 17:46	5/8/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Burnett Patrick	CA	O	See Rema	18	S.dm	-3,867	14.60	-265		179	D
1/7/26 17:27	8/7/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Pelish Henry E.	MA	O	Chief Sc	10	S.dm	-8,315	89.81	-93		83	D
1/7/26 17:26	8/25/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Noci Darlene	MA	O	Chief De	16	S.dm	-8,248	82.12	-100		58	D
1/7/26 17:26	1/5/26	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Miller Deborah Ann	MA	O	GC	9	S.dm	-10,771	97.99	-110		60	D
1/7/26 17:26	1/5/26	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Turner Christopher Durant	MA	O	Chief Me	2	S.dm	-1,041	91.08	-11		73	D
1/7/26 17:25	1/5/26	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Balcom Alexandra	MA	O	CFO	14	S.dm	-18,579	89.10	-209		99	D
1/7/26 17:25	8/15/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Porter James Richard	MA	DO	P,CEO	15	S.dm	-32,398	81.87	-396		325	D
1/7/26 17:11	1/5/26	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kalofonos Isabel	CA	O	Chief Co	1	S.d	-138	55.00	-3		1	D
1/7/26 16:30	2/19/25	ALXO	Alx Oncology Holdings Inc	DE	Health	Drug	Pharmaceutical Preparations	Pinto Shelly	CA	O	Interim	7	S	-13	1.07	-12		90	D
1/7/26 16:23	1/5/26	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Milanova Tsveta	MA	O	Chief Co	5	S.d	-400	30.62	-13		35	D
1/7/26 16:15	1/5/26	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jaen Juan C.	CA	O	P	6	S.m	-6,310	21.97	-287		1,459	I
1/7/26 16:05	1/5/26	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	Inrig Jula	CA	O	Chief Me	8	S.dm	-989	31.37	-32		90	D
1/7/26 16:05	1/5/26	IRWD	Ironwood Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Silver Ronald	MA	O	Principa	3	S	-187	3.71	-50		280	D
1/7/26 12:45	1/5/26	ACTU	Actuate Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Thomson Todd S	CA	DT		1	S	-1,624	5.80	-280		2,354	I
1/6/26 21:36	1/2/26	SYRE	Spyre Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Turtle Cameron	MA	DO	CEO	3	S	-1,945	25.94	-75		702	D
1/6/26 21:30	1/2/26	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	Francis Chris	MA	O	See Rema	4	S.d	-10,008	14.40	-695		25	D
1/6/26 20:26	1/5/26	TERN	Terns Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Burroughs Amy L.	CA	DO	CEO	1	S.d	-2,718	38.10	-71		147	D
1/6/26 20:25	1/2/26	TERN	Terns Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kuriakose Emil	CA	O	Chief Me	5	S	-84	9.97	-8		54	D
1/6/26 20:22	1/2/26	ATAI	Ataibeckley Inc.	DE	Health	Drug	Pharmaceutical Preparations	Feilding-Mellen Cosmo	NY	D		1	S	-154	3.90	-40		7,663	D
1/6/26 20:00	1/2/26	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Thompson Travis Alvin	X0	O	Chief Ac	7	S.dm	-251	17.48	-14		66	D
1/6/26 20:00	1/2/26	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Skynner Michael	X0	O	CTO	6	S.dm	-166	9.80	-17		162	D
1/6/26 20:00	1/2/26	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Hannay Michael Charles Ferguson	X0	O	CHIEF PR	6	S.dm	-87	8.94	-10		98	D
1/6/26 20:00	1/2/26	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Milnes Alistair	X0	O	COO	6	S.dm	-194	9.93	-20		137	D
1/6/26 20:00	1/2/26	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Young Alethia	X0	O	CFO	5	S.dm	-77	7.81	-10		87	D
1/6/26 20:00	1/2/26	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	Lee Kevin	X0	DO	CEO	6	S.dm	-515	9.67	-53		619	D
1/6/26 19:47	1/2/26	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	Kozarich John W	FL	D		7	S	-607	162.51	-4		46	D
1/6/26 18:14	1/5/26	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	Shannon John Patrick Jr	IL	DO	See Rema	2	S.d	-350	7.26	-48		2,798	D
1/6/26 17:35	1/2/26	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	Swayze Eric	CA	O	EVP Rese	10	S.adm	-5,103	63.52	-80		48	D
1/6/26 17:31	12/1/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Welgus Howard G.	CA	D		17	S.d	-2,709	16.00	-169		192	D
1/6/26 17:30	1/5/26	PCRX	Pacira Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Riker Lauren	CA	O	SVP,Fina	2	S	-181	25.81	-7		60	D
1/6/26 16:54	1/2/26	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Lewis Joel	GA	DO	P,CEO	8	S.dm	-759	3.76	-202		899	D
1/6/26 16:54	1/2/26	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Callicutt Jack W	GA	O	CFO	7	S.dm	-1,036	4.61	-225		15	D
1/6/26 16:53	1/2/26	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	Jamil Khurram	GA	O	Chief Me	5	S.dm	-1,077	4.84	-222		26	D
1/6/26 16:31	11/1/24	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Causey Christopher	MD	D		5	S.d	-2,912	447.27	-7		5	D
1/6/26 16:31	1/5/26	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Malcolm Jan	MD	D		4	S	-355	417.30	-1		1	D
1/6/26 16:30	1/2/26	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Schambye Hans T.	G7	DO	CEO	3	S.d	-25	8.99	-3		5	D
1/6/26 16:30	1/2/26	FULC	Fulcrum Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gould Robert J	MA	D		2	S	-344	11.45	-30		485	D
1/6/26 16:30	1/2/26	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Winslow Garrett	G7	O	GC	3	S.d	-9	9.10	-1		2	D
1/6/26 16:30	1/2/26	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Firmani Lori	G7	O	CFO	3	S.d	-5	8.94	-1		1	D
1/6/26 16:24	1/2/26	BIOA	Bioage Labs, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Rubin Paul D	CA	O	Chief Me	3	S.d	-1,013	10.74	-94	-100	0	D
1/6/26 16:18	1/2/26	RPRX	Royalty Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	Coyne Terrance P.	NY	O	EVP,CFO	5	S	-13,534	38.90	-348		829	I
1/6/26 16:16	1/5/26	CTNM	Contineum Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lorrain Daniel S.	CA	O	Chief Sc	4	S	-212	13.65	-16		173	D
1/6/26 16:06	1/5/26	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Baumal Caroline	MA	O	Chief Me	3	S	-228	29.63	-8		93	D
1/6/26 16:03	11/12/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	Schaeffer Orlov S Nicole	NJ	O	Chief Pe	12	S.dm	-59,161	115.98	-510		121	D
1/6/26 16:02	12/24/25	LYEL	Lyell Immunopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bulis Veronica Sanchez	CA	O	VP,Corpo	2	S.m	-78	33.76	-2		9	D
1/5/26 21:50	1/6/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	O'Brien Patrick	CA	O	COO	2	S.m	-3,859	44.53	-87		527	D
1/5/26 21:41	1/5/26	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hamilton James C	CA	O	Chief Me	6	S.m	-4,908	36.94	-133		272	D
1/5/26 21:39	4/9/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Anzalone Christopher Richard	CA	DO	CEO	11	S.dm	-32,626	36.11	-904		4,062	D
1/5/26 20:31	1/5/26	VKTX	Viking Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Zante Greg	CA	O	CFO	5	S.d	-14,472	57.86	-250		190	D
1/5/26 20:31	1/5/26	VKTX	Viking Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Mancini Marianna	CA	O	COO	4	S.d	-4,554	37.23	-122		409	D
1/5/26 20:28	1/5/26	VKTX	Viking Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Lian Brian	CA	DO	P,CEO	5	S.d	-33,427	47.09	-710		2,499	D
1/5/26 20:25	1/2/26	VKTX	Viking Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Foehr Matthew W	CA	D		1	S.d	-562	35.11	-16		135	D
1/5/26 20:02	1/2/26	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Khara Rahul	MA	O	GC	4	S.d	-1,462	64.52	-23		38	D
1/5/26 18:01	3/20/25	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	Hecht Beth	IL	O	See Rema	4	S	-581	6.46	-90		1,354	D
1/5/26 16:30	1/2/25	XLO	Xilio Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Brennan Kevin M.	MA	O	SVP,FINA	2	S.d	-3	0.8123	-4		6	D
1/5/26 16:30	1/2/25	XLO	Xilio Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Frankenfield Christopher James	MA	O	CFO	2	S.d	-11	0.8126	-14		25	D
1/5/26 16:26	6/5/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	Callos Andrew	CA	O	EVP,Chie	14	S.d	-7,619	53.40	-143		68	D
1/5/26 16:20	12/31/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Bredt David	MA	O	Chief Sc	11	S	-1,686	18.41	-92		469	D
1/5/26 16:19	12/31/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Yeleswaram Krishnaswamy	MA	O	Chief De	1	S	-85	30.05	-3		297	D
1/5/26 16:15	1/2/26	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hunter Heather	MI	O	COO	2	S	-6	1.01	-6		135	D
1/5/26 16:13	1/2/26	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Neri Jesse	MI	O	SVP,CFO	5	S	-4	0.9533	-4		127	D
1/5/26 16:07	1/2/26	RARE	Ultragenyx Pharmaceutical Inc.	DE	Health	Drug	Pharmaceutical Preparations	Horn Howard	CA	O	CFO	5	S	-900	38.43	-23		106	D
1/2/26 21:30	12/6/24	OGEN	Oragenics Inc	FL	Health	Drug	Pharmaceutical Preparations	Dunton Alan W	FL	D		3	S.d	-391	13.02	-30		66	D
1/2/26 21:00	1/2/26	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Meyer Andrew Hollman	CA	O	Chief Bu	10	S.d	-4,221	41.43	-102		85	D
1/2/26 21:00	1/2/26	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Diraimondo Thomas	CA	O	Chief Sc	2	S.d	-266	35.46	-8		156	D
1/2/26 21:00	1/2/26	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Campbell David Alan	CA	DO	P,CEO	7	S.d	-6,607	51.59	-128		382	D
1/2/26 21:00	1/2/26	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Winter Charles M.	CA	O	Chief Te	1	S.d	-33	13.73	-2		106	D
1/2/26 21:00	1/2/26	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	McIver Zachariah	CA	O	Chief Me	1	S.d	-37	13.73	-3		52	D
1/2/26 21:00	1/2/26	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Dobek Maria	CA	O	VP,Accou	1	S.d	-20	13.73	-1		34	D
1/2/26 20:25	1/2/26	ORKA	Oruka Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sandler Laura Lee	CA	O	COO	1	S.d	-371	28.52	-13		205	D
1/2/26 20:18	12/30/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Burns James William	MA	O	GC	4	S.d	-1,451	46.09	-31		32	D
1/2/26 20:16	12/30/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Goff Brian	MA	DO	CEO	4	S.d	-2,000	32.56	-61		143	D
1/2/26 20:15	10/30/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Gheuens Sarah	MA	O	Chief Me	8	S.d	-1,173	36.88	-32		65	D
1/2/26 20:14	12/30/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Jones Cecilia	MA	O	CFO	5	S.d	-479	36.33	-13		37	D
1/2/26 19:02	12/31/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Saad Mark E	NY	D		3	S.d	-8,354	144.74	-58		10	D
1/2/26 18:49	1/2/26	XENE	Xenon Pharmaceuticals Inc.	A1	Health	Drug	Pharmaceutical Preparations	Mortimer Ian	A1	DO	P,CEO,IN	5	S.dm	-6,142	42.27	-145		46	D
1/2/26 17:25	12/31/25	VRDN	Viridian Therapeutics, Inc.De	DE	Health	Drug	Pharmaceutical Preparations	Tousignant Jennifer	MA	O	GC	1	S	-71	31.16	-2	-100	0	D
1/2/26 17:13	12/30/25	SLRX	Salarius Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Hanish Arnold C	TX	D		1	S	0	0.6296	0		5	M
1/2/26 16:30	8/21/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Mahon Paul A	MD	O	EVP,GC	23	S.d	-90,473	371.25	-244		37	D
1/2/26 16:19	12/31/24	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Goeltz II Robert C.	CA	O	CFO	5	S.m	-711	21.67	-33		92	D
1/2/26 16:15	12/31/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	Amado Rafael	MA	O	See Rema	6	S.d	-979	28.01	-35		52	D
12/31/25 21:00	12/29/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Sukhatme Mayukh	X0	DO	P,CIO	4	S.dm	-45,135	16.99	-2,657		18,837	D
12/31/25 16:05	12/29/25	CVKD	Cadrenal Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Szot Matthew K	FL	O	CFO	7	S.m	-397	11.92	-33		31	D
12/30/25 17:54	12/23/25	ALZN	Alzamend Neuro, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ault Milton C III	NV	D		12	S.dm	-2,222	2.45	-908		124	D
12/30/25 17:46	12/26/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ferrari Mauro	CA	D		2	S	-1,021	62.69	-16		69	D
12/30/25 16:17	12/30/25	MBIO	Mustang Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Herskowitz Neil	MA	D		2	S	0	1.05	0		0	D
12/30/25 16:16	12/30/25	MBIO	Mustang Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Chill Adam J.	MA	D		1	S	0	1.00	0		0	D
12/30/25 16:12	12/29/25	CTNM	Contineum Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Watkins Tim	CA	O	CMO,Head	1	S.d	-44	12.06	-4	-100	0	D
12/30/25 16:01	12/26/25	COGT	Cogent Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Kearns Evan	MA	O	GC	1	S	-2,516	38.70	-65		109	D
12/30/25 16:01	12/26/25	COGT	Cogent Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Green John L.	MA	O	CFO	1	S	-2,978	38.68	-77		132	D
12/30/25 16:01	12/26/25	COGT	Cogent Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Sachs Jessica	MA	O	Chief Me	1	S	-3,198	38.70	-83		134	D
12/30/25 16:01	12/26/25	COGT	Cogent Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Robinson John Edward	MA	O	Chief Sc	1	S	-3,487	38.74	-90		140	D
12/30/25 13:49	12/29/25	RARE	Ultragenyx Pharmaceutical Inc.	DE	Health	Drug	Pharmaceutical Preparations	Huizenga Theodore Alan	CA	O	SVP,Chie	5	S.d	-53	41.25	-1		50	D
12/29/25 21:55	12/22/25	OLMA	Olema Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Harmon Cyrus	CA	D		3	S.m	-435	9.83	-44		886	D
12/29/25 21:11	12/24/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	Heerma Peter	CA	O	Chief Co	8	S.dm	-808	27.33	-30		128	D
12/29/25 21:05	12/24/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	Rote William E.	CA	O	Chief Re	6	S.d	-2,871	34.11	-84		101	D
12/29/25 21:00	12/23/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Pulik Richard	X0	O	CFO	1	S.d	-9,122	22.43	-407		239	D
12/29/25 21:00	12/23/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	Venker Eric	X0	O	P,Immuno	21	S.dm	-106,489	14.07	-7,568		1,655	D
12/29/25 20:59	12/24/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	Calvin Sandra	CA	O	SVP,Chie	8	S.d	-4,737	29.06	-163		64	D
12/29/25 20:44	12/24/25	CRVS	Corvus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Orbimed Advisors LLC	NY	DT		9	S.dm	-33,804	10.60	-3,190		16,931	I
12/29/25 20:42	12/24/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Thompson Peter A.	MA	D		4	S.dm	-11,276	8.54	-1,320		10,762	I
12/29/25 18:42	12/22/25	EOLS	Evolus, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Moatazedi David	CA	DO	See Rema	6	S.m	-3,076	11.21	-274		523	D
12/29/25 18:42	12/22/25	EOLS	Evolus, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Avelar Rui	CA	O	See Rema	4	S	-444	12.40	-36		367	D
12/29/25 16:30	12/24/25	PTN	Palatin Technologies Inc	NJ	Health	Drug	Pharmaceutical Preparations	Wills Stephen T	NJ	O	EVP,CFO,	1	S	-9	16.75	-1		63	D
12/29/25 16:30	7/9/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	Seshadri Vishwas	OH	DO	CEO	6	S.m	-1,238	5.77	-215		1,355	D
12/29/25 16:09	12/24/25	DVAX	Dynavax Technologies Corp	DE	Health	Drug	Pharmaceutical Preparations	Novack David F	CA	O	P,COO	4	S.d	-1,267	14.59	-87		63	D
12/29/25 12:24	12/24/25	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	Calkins Daniel	MA	O	CFO	9	S.m	-115	7.28	-16		114	D
12/23/25 21:42	12/19/25	OLMA	Olema Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Clark Ian T	CA	D		1	S.d	-7,873	29.73	-265	-100	0	D
12/23/25 21:41	12/19/25	OLMA	Olema Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Myles David C.	CA	O	CH. DISC	2	S.m	-1,788	23.21	-77		766	D
12/23/25 21:40	12/19/25	OLMA	Olema Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Zojwalla Naseem	CA	O	Chief Me	2	S.dm	-7,781	26.17	-297		116	D
12/23/25 20:09	12/22/25	OKUR	Onkure Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Saccomano Nicholas A	CO	DO	P,CEO	4	S.m	-3	2.88	-1		7	D
12/23/25 20:08	12/22/25	OKUR	Onkure Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Leverone Jason A.	CO	O	CFO	4	S.m	-12	2.88	-4		16	D
12/23/25 18:52	12/22/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Ramasastry Saira	CA	D		4	S.dm	-917	28.49	-32	-100	0	D
12/23/25 18:50	12/19/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Grey Michael G	CA	D		3	S.d	-11,100	74.00	-150		280	D
12/23/25 18:01	12/16/24	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Waddill William D.	CA	D		7	S.dm	-2,781	58.11	-48		70	D
12/23/25 18:01	12/19/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Vakiener Victoria	CA	D		2	S	-877	46.05	-19		36	D
12/23/25 18:01	1/23/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	Olukotun Adeoye Y	CA	D		3	S	-754	54.58	-14		37	D
12/23/25 16:41	12/22/25	IMNM	Immunome Inc.	DE	Health	Drug	Pharmaceutical Preparations	Barchas Isaac	WA	D		1	S	-8,330	21.74	-383		4,166	I
12/23/25 16:33	12/18/24	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	Sullivan Louis W	MD	D		2	S.d	-12,829	398.92	-32		3	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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