Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	#o	#f	T	TVal	Price	Qty	oc	Own	H
12/30/25 21:03	12/23/25	CLNN	Clene Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	3	S.dm	-1,864	6.67	-279		796	I
12/30/25 17:54	12/23/25	ALZN	Alzamend Neuro, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	S.dm	-947	2.43	-390		82	D
12/30/25 17:46	10/1/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	11	S.dm	-27,773	64.89	-428		4,439	D
12/30/25 16:34	12/29/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	8	19	S.d	-10,280	64.81	-159		718	D
12/30/25 16:31	12/23/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	9	59	S.edm	-330,782	463.17	-714		726	D
12/30/25 16:17	12/30/25	MBIO	Mustang Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	0	0.9641	0		1	D
12/30/25 16:12	12/29/25	CTNM	Contineum Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S.d	-95	12.15	-8		171	D
12/30/25 16:01	12/26/25	COGT	Cogent Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	S	-12,179	38.71	-315		515	D
12/30/25 16:00	11/13/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	2	29	S.e	-1,539,328	521.37	-2,952		95,034	D
12/30/25 13:49	12/29/25	RARE	Ultragenyx Pharmaceutical Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S	-365	32.88	-11		149	D
12/29/25 21:55	12/19/25	OLMA	Olema Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	S.dm	-17,039	28.97	-588		1,573	D
12/29/25 21:11	12/1/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	7	11	S.dm	-11,297	34.90	-324		930	D
12/29/25 21:00	12/11/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	8	17	S.dm	-391,146	21.22	-18,433		139,172	D
12/29/25 20:44	12/5/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	16	S.dm	-58,771	37.15	-1,582		11,516	D
12/29/25 18:42	12/22/25	EOLS	Evolus, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-92	7.15	-13		711	D
12/29/25 17:27	12/2/25	HOWL	Werewolf Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	31	S.m	-6,294	1.12	-5,628		17,018	I
12/29/25 17:14	12/23/25	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	1	1	S.dm	-5,197	35.84	-145		15	D
12/29/25 16:58	12/26/25	RPRX	Royalty Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	3	12	S.m	-30,277	38.97	-777		2,057	I
12/29/25 16:30	12/24/25	PTN	Palatin Technologies Inc	NJ	Health	Drug	Pharmaceutical Preparations	1	1	S	-9	16.75	-1		63	D
12/29/25 16:30	12/29/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S	-205	5.10	-40		1,252	D
12/29/25 16:09	12/24/25	DVAX	Dynavax Technologies Corp	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.d	-465	15.49	-30		63	D
12/29/25 12:24	12/24/25	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	6	13	S.dm	-554	9.94	-56		708	D
12/29/25 11:40	11/24/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	1	17	S.dm	-272	3.92	-69		6	D
12/23/25 20:09	12/22/25	OKUR	Onkure Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-1	2.97	0		24	D
12/23/25 18:52	12/22/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	5	S.d	-11,639	74.14	-157		280	D
12/23/25 18:45	11/17/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	8	S	-1,569	20.92	-75		2,095	I
12/23/25 16:41	12/22/25	IMNM	Immunome Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-8,330	21.74	-383		4,166	I
12/23/25 16:30	12/23/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	4	6	S.dm	-3,011	47.22	-64		55	D
12/23/25 16:24	12/23/25	EQ	Equillium, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	3	S.dm	-205	1.43	-144		127	D
12/23/25 16:16	12/19/25	FOLD	Amicus Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	9	S.dm	-4,019	10.54	-381		2,422	D
12/23/25 16:02	11/24/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	13	S.dm	-5,086	18.47	-275		693	D
12/23/25 16:02	12/19/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	2	2	S.d	-2,950	15.71	-188		720	D
12/22/25 20:48	12/22/25	PGEN	Precigen, Inc.	VA	Health	Drug	Pharmaceutical Preparations	2	3	S.m	-21,090	4.13	-5,102		124,057	I
12/22/25 17:52	12/22/25	ZYME	Zymeworks Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.d	-1,284	27.02	-48		133	D
12/22/25 16:15	12/18/25	LITS	Lite Strategy, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-946	1.37	-691		3,675	D
12/22/25 16:04	12/19/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	5	S.d	-5,430	50.50	-108		2,347	D
12/19/25 21:30	12/18/25	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	S.d	-2,314	11.18	-207		671	D
12/19/25 21:00	12/19/25	TYRA	Tyra Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	5	S.m	-9,570	18.34	-522		4,130	I
12/19/25 20:00	12/17/25	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	3	5	S.dm	-2,167	5.67	-382		3,802	D
12/19/25 17:38	12/19/25	ORKA	Oruka Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.d	-214	30.61	-7		2	D
12/19/25 17:17	12/1/25	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	4	5	S.d	-1,497	7.23	-207		4,908	D
12/19/25 17:00	12/19/25	SVRA	Savara Inc	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-121	6.06	-20		2,534	D
12/19/25 17:00	12/17/25	ADTX	Aditxt, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	0	2.50	0		0	D
12/19/25 16:47	12/18/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	5	6	S.m	-2,414	87.46	-28		450	D
12/19/25 16:30	12/18/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	7	S.d	-840	10.73	-78		847	D
12/19/25 16:15	12/18/25	VTYX	Ventyx Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S.d	-463	7.72	-60		2,862	D
12/19/25 16:12	11/3/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	7	10	S.d	-44,330	193.88	-229		1,151	D
12/19/25 16:08	12/16/25	GALT	Galectin Therapeutics Inc	NV	Health	Drug	Pharmaceutical Preparations	5	19	S.dm	-5,648	5.85	-966		6,757	D
12/19/25 16:05	12/17/25	PVLA	Palvella Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-786	91.35	-9	-100	0	D
12/19/25 15:43	12/18/25	MNPR	Monopar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-344	67.15	-5		9	D
12/18/25 20:05	12/16/25	SRPT	Sarepta Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-294	22.31	-13		193	D
12/18/25 18:14	12/17/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	8	S.dm	-98,616	82.48	-1,196		4,075	I
12/18/25 18:08	11/3/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	S.d	-927	15.84	-59		172	D
12/18/25 17:35	12/16/25	RCUS	Arcus Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	16	S.dm	-10,281	21.01	-489		4,178	D
12/18/25 17:23	12/17/25	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	3	5	S.dm	-932	26.39	-35		353	D
12/18/25 16:34	12/16/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	2	4	S.d	-454	19.17	-24		45	D
12/18/25 16:19	12/16/25	ORGO	Organogenesis Holdings Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	3	S.m	-2,700	5.16	-523		12,249	D
12/18/25 16:11	12/17/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	7	S.d	-1,719	27.18	-63		1,284	M
12/18/25 16:10	12/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	S	-231	3.65	-63		2,331	D
12/18/25 16:06	12/16/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	5	S.d	-1,367	24.37	-56		499	D
12/18/25 16:04	12/16/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	5	9	S.d	-20,131	27.11	-743		783	D
12/18/25 15:13	12/16/25	APLT	Applied Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-5	0.1120	-43		65	D
12/17/25 19:21	12/16/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	5	S.d	-1,118	10.82	-103		718	D
12/17/25 17:53	11/3/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	9	19	S.dm	-8,638	25.46	-339		1,747	D
12/17/25 17:25	12/5/25	HRMY	Harmony Biosciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S.d	-1,951	39.52	-49	-100	0	D
12/17/25 16:47	12/10/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	4	7	S.dm	-43,221	320.25	-135	0	52,514	D
12/17/25 16:38	12/15/25	KNSA	Kiniksa Pharmaceuticals International, Plc		Health	Drug	Pharmaceutical Preparations	6	11	S.dm	-19,973	39.08	-511		382	D
12/17/25 16:10	12/8/25	FULC	Fulcrum Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-58,587	13.97	-4,194		6,549	I
12/17/25 16:05	12/15/25	VERA	Vera Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	5	S.d	-1,897	38.83	-49		129	D
12/16/25 18:36	12/12/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	4	6	S.d	-2,813	201.56	-14		110	D
12/16/25 18:27	12/15/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	13	S.dm	-46,383	65.59	-707		7,277	D
12/16/25 18:00	12/12/25	CLRB	Cellectar Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-1	3.70	0		0	I
12/16/25 17:00	12/12/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S.d	-1,786	22.98	-78		237	D
12/16/25 14:59	12/12/25	NATR	Natures Sunshine Products Inc	UT	Health	Drug	Pharmaceutical Preparations	4	4	S	-401	20.69	-19		255	D
12/15/25 17:24	12/15/25	ZNTL	Zentalis Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	1	1	S	-9,975	1.33	-7,500		6,460	I
12/15/25 16:51	12/11/25	PAHC	Phibro Animal Health Corp	DE	Health	Drug	Pharmaceutical Preparations	1	13	S.dm	-7,597	43.05	-176		91	I
12/15/25 16:38	12/12/25	OGEN	Oragenics Inc	FL	Health	Drug	Pharmaceutical Preparations	1	1	S.d	0	0.9429	0		35	D
12/15/25 16:30	12/11/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	6	S.dm	-6,052	106.99	-57		29	D
12/15/25 16:18	10/24/25	CRBP	Corbus Pharmaceuticals Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	S.dm	-1,058	14.75	-72		2,563	D
12/12/25 17:30	12/10/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	1	S	-116	9.99	-12		81	D
12/12/25 16:40	12/10/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	7	S.d	-41,325	536.29	-77		2,148	D
12/11/25 21:47	12/9/25	PCRX	Pacira Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S.dm	-989	24.10	-41		235	D
12/11/25 20:50	8/21/25	GNLX	Genelux Corp	DE	Health	Drug	Pharmaceutical Preparations	5	5	S.m	-156	4.16	-37		1,402	D
12/11/25 17:35	12/9/25	IRD	Opus Genetics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-8,600	2.15	-4,000		5,492	D
12/11/25 17:19	12/9/25	JAZZ	Jazz Pharmaceuticals Plc	L2	Health	Drug	Pharmaceutical Preparations	6	9	S.dm	-22,745	175.92	-129		537	D
12/11/25 16:21	12/9/25	BIOA	Bioage Labs, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-918	10.56	-87	-100	0	D
12/10/25 21:45	12/8/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	8	9	S.dm	-15,139	14.60	-1,037		515	D
12/10/25 20:51	12/8/25	XCUR	Exicure, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-3,774	8.71	-433	-100	0	D
12/10/25 17:45	11/26/25	MRUS	Merus N.V.	P7	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-960	95.95	-10		11	D
12/10/25 16:56	12/9/25	SNSE	Sensei Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.dm	-575	10.29	-56		323	D
12/10/25 16:32	11/6/25	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	4	4	S.d	-3,881	45.07	-86		348	D
12/10/25 16:30	11/24/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	17	S.dm	-99,188	95.57	-1,038		19,309	I
12/10/25 16:29	12/8/25	MLTX	Moonlake Immunotherapeutics	E9	Health	Drug	Pharmaceutical Preparations	2	2	S.m	-5,987	14.86	-403		5,853	D
12/10/25 16:24	12/8/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	15	S.dm	-6,466	28.36	-228		466	D
12/9/25 19:40	12/5/25	XENE	Xenon Pharmaceuticals Inc.	A1	Health	Drug	Pharmaceutical Preparations	1	2	S.m	-1,147	45.33	-25		46	D
12/9/25 19:07	12/9/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	3	7	S.d	-3,249	27.07	-120		427	D
12/9/25 18:16	11/24/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	10	S.d	-695	13.98	-50		830	D
12/9/25 18:01	10/7/25	EBS	Emergent Biosolutions Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	S.d	-842	10.67	-79		452	D
12/5/25 20:00	12/4/25	DNTH	Dianthus Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	2	2	S.dm	-8,283	38.25	-217		4	D
12/5/25 18:53	12/5/25	ENTA	Enanta Pharmaceuticals Inc		Health	Drug	Pharmaceutical Preparations	7	9	S	-183	14.22	-13		1,346	D
12/5/25 18:02	12/3/25	TBPH	Theravance Biopharma, Inc.	CA	Health	Drug	Pharmaceutical Preparations	2	4	S.d	-3,050	18.53	-165		338	D
12/5/25 16:21	12/3/25	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	1	4	S.d	-787	30.56	-26		74	D
12/5/25 16:16	12/3/25	VRTX	Vertex Pharmaceuticals Inc / Ma	MA	Health	Drug	Pharmaceutical Preparations	5	7	S.dm	-70,874	445.43	-159		141	D
12/5/25 16:11	12/5/25	DYN	Dyne Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-76	20.72	-4		451	D
12/4/25 19:39	12/2/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	3	S.dm	-38,882	134.40	-289		7,352	D
12/4/25 19:00	12/2/25	QTTB	Q32 Bio Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-109	3.46	-32		139	D
12/3/25 21:52	12/1/25	SYRE	Spyre Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S	-1,485	24.75	-60		702	D
12/3/25 21:19	12/2/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	5	15	S.dm	-21,367	80.26	-266		2,915	M
12/3/25 20:00	12/1/25	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	3	S.d	-711	30.47	-23		85	D
12/3/25 19:01	12/1/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	12	18	S.dm	-25,385	74.97	-339		656	I
12/3/25 17:02	12/1/25	NUVB	Nuvation Bio Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	7	S.dm	-6,214	6.99	-889		42	D
12/3/25 16:39	12/1/25	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-94	14.35	-7		176	D
12/3/25 16:28	10/1/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	3	S.d	-647	43.16	-15		67	D
12/2/25 16:43	11/28/25	PBH	Prestige Consumer Healthcare Inc.		Health	Drug	Pharmaceutical Preparations	1	1	S.m	-60	60.00	-1		42	D
12/2/25 16:34	12/1/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	8	19	S.d	-5,228	26.32	-199		4,472	D
12/1/25 16:07	11/26/25	CVRX	Cvrx, Inc.	NJ	Health	Drug	Pharmaceutical Preparations	1	4	S.m	-637	10.18	-63		4,051	I
11/26/25 16:02	11/24/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	6	8	S	-973	11.45	-85		4,441	D
11/25/25 20:30	11/25/25	NKTR	Nektar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	3	3	S.d	-217	54.28	-4		95	D
11/25/25 17:31	11/24/25	TGTX	Tg Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-163	32.57	-5		224	D
11/25/25 16:44	11/21/25	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	6	S	-453	5.54	-82		2,816	D
11/25/25 16:17	11/25/25	ABT	Abbott Laboratories	IL	Health	Drug	Pharmaceutical Preparations	1	1	S	-203	128.02	-2		30	D
11/24/25 16:42	11/20/25	GRTX	Galera Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-1	0.0201	-70		195	D
11/24/25 16:30	11/21/25	TRDA	Entrada Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-3,609	8.83	-409		8,223	D
11/24/25 16:05	11/7/25	REGN	Regeneron Pharmaceuticals, Inc.	NY	Health	Drug	Pharmaceutical Preparations	3	3	S.d	-5,104	663.57	-8		11	D
11/21/25 21:41	11/20/25	PRAX	Praxis Precision Medicines, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S.d	-40,663	115.31	-353		4,453	D
11/21/25 18:13	11/20/25	SGMT	Sagimet Biosciences Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-290	7.69	-38		81	D
11/21/25 18:07	11/20/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	8	S.dm	-61,610	43.84	-1,405		8,923	I
11/21/25 16:59	11/19/25	LFVN	Lifevantage Corp		Health	Drug	Pharmaceutical Preparations	1	2	S	-331	6.80	-49		97	I
11/20/25 16:05	11/18/25	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	5	S	-149	3.68	-40		1,934	D
11/20/25 13:42	11/19/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	2	2	S.d	-287	23.53	-12		141	D
11/19/25 18:00	11/18/25	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	3	3	S.d	-1,011	22.79	-44		82	D
11/19/25 16:21	11/17/25	AMRX	Amneal Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	2	2	S.d	-2,158	11.87	-182		437	D
11/19/25 16:06	11/17/25	CYPH	Cypherpunk Technologies Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-5,069	3.14	-1,614		132	I
11/19/25 16:05	11/17/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	5	7	S.dm	-27,289	452.34	-60		194	D
11/19/25 16:05	11/17/25	IRWD	Ironwood Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-20	3.32	-6		235	D
11/19/25 16:01	11/17/25	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	2	2	S.d	-1,209	82.20	-15		86	D
11/18/25 19:04	11/17/25	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	S.d	-250	8.91	-28		2,194	D
11/18/25 16:30	11/15/25	MCRB	Seres Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	S.d	-45	17.30	-3		35	D
11/18/25 16:26	11/18/25	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-8	0.9855	-8		276	D
11/17/25 16:05	11/14/25	AVTX	Avalo Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.d	-163	14.33	-11	-100	0	D
11/14/25 18:43	11/12/25	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S.d	-1,666	8.85	-188		11	D
11/14/25 16:04	10/30/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	5	S.d	-278	43.77	-6		79	D
11/13/25 20:13	11/10/25	SEPN	Septerna, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-63	18.06	-4		93	D
11/13/25 18:06	11/12/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.d	-2,112	21.12	-100		23	D
11/13/25 16:41	11/11/25	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-97	4.86	-20		54	D
11/12/25 20:44	11/7/25	SPRO	Spero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-95	2.37	-40		869	D
11/12/25 20:36	11/10/25	LYEL	Lyell Immunopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	S	-14	16.12	-1		107	D
11/12/25 18:00	11/10/25	ASRT	Assertio Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-7	0.7597	-9		99	D
11/12/25 16:01	11/10/25	MRK	Merck & Co., Inc.	NJ	Health	Drug	Pharmaceutical Preparations	2	2	S	-1,336	85.13	-16		25	D
11/10/25 18:30	11/3/25	MURA	Mural Oncology Plc	L2	Health	Drug	Pharmaceutical Preparations	2	2	S	-25	2.09	-12		184	D
11/10/25 16:54	11/6/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	2	2	S.d	-2,034	28.96	-70		61	D
11/10/25 16:05	11/6/25	CTMX	Cytomx Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-462	4.54	-102		1,081	D
11/7/25 16:58	11/6/25	EVOK	Evoke Pharma Inc	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-96	10.65	-9		154	I
11/7/25 16:20	11/7/25	ARVN	Arvinas, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-2	9.89	0		32	D
11/6/25 18:12	11/4/25	ANTX	An2 Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-4	1.14	-4		243	D
11/5/25 18:17	11/4/25	TERN	Terns Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.d	-441	18.00	-25	-100	0	D
11/5/25 18:00	11/5/25	BGMS	Bio Green Med Solution, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	17	S.dm	-4,967	3.08	-1,614		1,632	D
11/5/25 16:30	11/3/25	PHAT	Phathom Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-7	13.51	-1		54	D
11/5/25 09:57	11/3/25	MTSR	Metsera, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-12	61.23	0	0	3,094	I
10/31/25 15:30	10/29/25	SYBX	Synlogic, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	0	1.81	0		13	D
10/28/25 19:51	10/28/25	VKTX	Viking Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	S.d	-3,932	35.31	-111		3,005	D
10/28/25 17:00	10/24/25	CVKD	Cadrenal Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	6	S.m	-193	14.03	-14		419	D
10/28/25 16:10	10/27/25	MRSN	Mersana Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.d	-1	9.90	0		3	D
10/27/25 17:19	10/23/25	PMVP	Pmv Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-1,520	1.52	-1,000		4,975	I
10/27/25 16:15	10/23/25	TNGX	Tango Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-4,847	10.15	-477		13,387	D
10/24/25 20:00	10/22/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	5	S.m	-249	0.8198	-303		246	D
10/24/25 16:56	10/22/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S.d	-1,406	48.86	-29		191	D
10/22/25 18:57	10/20/25	RANI	Rani Therapeutics Holdings, Inc.	CA	Health	Drug	Pharmaceutical Preparations	1	1	S.m	-15,711	2.65	-5,923		2,379	I
10/20/25 20:00	10/16/25	BYSI	Beyondspring Inc.		Health	Drug	Pharmaceutical Preparations	1	4	S.m	-548	1.72	-319		4,327	I
10/20/25 19:13	10/17/25	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	1	1	S.d	-4,186	192.71	-22		11	D
10/20/25 18:58	10/16/25	LVTX	Lava Therapeutics Nv	P7	Health	Drug	Pharmaceutical Preparations	1	3	S.m	-5,141	1.48	-3,473		5,294	D
10/17/25 17:53	10/15/25	KROS	Keros Therapeutics, Inc.		Health	Drug	Pharmaceutical Preparations	2	2	S	-180,635	17.75	-10,177	-100	11	I
10/17/25 16:28	10/16/25	SDGR	Schrodinger, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-29	21.07	-1		25	D
10/17/25 14:01	10/15/25	AQST	Aquestive Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S.d	-686	7.01	-98		794	D
10/15/25 16:32	10/6/25	SPRB	Spruce Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S	-10	19.14	-1		1	I
10/14/25 20:11	10/10/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S.d	-2,792	50.77	-55		950	D
10/10/25 19:17	10/10/25	ZVRA	Zevra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.d	-211	10.82	-20		222	D
10/9/25 16:22	8/19/25	HOOK	Hookipa Pharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-21	0.8217	-25		54	D
10/8/25 16:16	10/7/25	CARM	Carisma Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.dm	-139	0.2565	-541	-100	0	D
10/8/25 16:10	10/6/25	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	1	2	S	-32	3.59	-9		1,044	D
10/6/25 16:45	10/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	7	7	S.m	-93	8.41	-11		831	D
10/3/25 21:58	10/2/25	ELTP	Elite Pharmaceuticals Inc /Nv/	NJ	Health	Drug	Pharmaceutical Preparations	1	1	S	-499	0.6240	-800		3,500	D
10/3/25 16:56	10/1/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-2	6.30	0		10	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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