Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	#o	#f	T	TVal	Price	Qty	oc	Own	H
4/6/26 19:56	4/6/26	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	5	9	S.dm	-3,730	33.25	-112		546	D
4/6/26 18:30	4/2/26	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	5	5	S.m	-70	4.94	-14		1,025	D
4/6/26 17:43	4/6/26	CTNM	Contineum Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	10	S.dm	-545	15.19	-36		178	D
4/6/26 17:32	4/2/26	CLNN	Clene Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	11	S.m	-1,765	5.02	-352		709	I
4/6/26 16:42	3/17/26	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	9	55	S.dm	-246,970	505.09	-489		791	D
4/6/26 16:11	4/2/26	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	13	S.d	-2,458	31.46	-78		427	D
4/3/26 21:30	4/1/26	SYRE	Spyre Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	S.d	-2,734	43.43	-63		756	D
4/3/26 19:48	4/2/26	IMNM	Immunome Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S.dm	-2,965	21.26	-139		420	D
4/3/26 18:17	4/2/26	WHWK	Whitehawk Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	S.d	-125	3.44	-36		1,028	D
4/3/26 17:59	4/2/26	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	5	14	S.dm	-5,183	19.27	-269		1,363	D
4/3/26 17:46	4/1/26	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	14	S.dm	-5,286	25.31	-209		1,624	D
4/3/26 17:45	1/8/26	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	3	5	S.d	-508	6.70	-76		3,043	D
4/3/26 17:09	2/26/26	JAZZ	Jazz Pharmaceuticals Plc	L2	Health	Drug	Pharmaceutical Preparations	5	7	S.dm	-15,299	191.20	-80		520	D
4/3/26 17:00	4/2/26	CAPR	Capricor Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	S.dm	-5,262	30.50	-173		39	D
4/3/26 16:53	4/1/26	VRTX	Vertex Pharmaceuticals Inc / Ma	MA	Health	Drug	Pharmaceutical Preparations	12	32	S.dm	-76,498	477.95	-160		405	D
4/3/26 16:30	3/12/26	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	10	S.dm	-14,510	100.65	-144		594	D
4/3/26 16:12	3/20/26	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	10	S.dm	-3,186	36.19	-88		460	D
4/3/26 16:10	4/1/26	DYN	Dyne Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	6	S.m	-15,843	19.13	-828		5,672	D
4/3/26 16:07	3/30/26	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	5	21	S.dm	-42,281	160.83	-263		932	D
4/3/26 16:07	1/13/26	BIOA	Bioage Labs, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	5	S.d	-5,202	18.33	-284		999	D
4/3/26 16:05	4/1/26	EBS	Emergent Biosolutions Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-34	8.44	-4		63	D
4/3/26 16:01	2/9/26	REGN	Regeneron Pharmaceuticals, Inc.	NY	Health	Drug	Pharmaceutical Preparations	4	6	S.d	-4,299	785.35	-5		26	D
4/3/26 15:14	4/1/26	AVTX	Avalo Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S.dm	-693	16.45	-42		21	D
4/3/26 09:00	4/1/26	ERAS	Erasca, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S.d	-2,284	10.38	-220		25	D
4/2/26 20:09	4/1/26	TNGX	Tango Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	7	S.d	-2,539	14.69	-173		2,001	D
4/2/26 19:43	4/1/26	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	14	33	S.dm	-50,326	80.13	-628		856	D
4/2/26 19:43	4/1/26	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	5	9	S.d	-5,814	207.06	-28		166	D
4/2/26 18:19	4/1/26	RARE	Ultragenyx Pharmaceutical Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	10	S.m	-2,698	22.66	-119		3,308	D
4/2/26 18:15	4/1/26	TERN	Terns Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.d	-3,851	38.96	-99		403	D
4/2/26 17:58	1/30/26	RPRX	Royalty Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	2	10	S.m	-22,801	42.84	-532		568	I
4/2/26 17:55	2/4/26	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	7	17	S.dm	-11,509	30.93	-372		1,052	D
4/2/26 16:39	3/9/26	TRDA	Entrada Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.m	-540	12.87	-42		337	D
4/2/26 16:29	4/1/26	BMY	Bristol Myers Squibb Co	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-1,850	61.67	-30		160	D
4/2/26 13:01	1/21/26	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.d	-5,518	30.35	-182		29	D
4/1/26 21:28	1/8/26	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	6	12	S.d	-5,372	51.18	-105		614	D
4/1/26 17:26	3/31/26	DNTH	Dianthus Therapeutics, Inc. /De/	DE	Health	Drug	Pharmaceutical Preparations	5	6	S.d	-28,027	81.71	-343	-100	0	D
4/1/26 16:34	4/1/26	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	5	14	S.d	-7,931	62.33	-127		772	D
3/31/26 21:30	3/31/26	COGT	Cogent Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-370,020	35.24	-10,500		5,503	I
3/31/26 21:03	3/31/26	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	9	12	S	-1,179	5.12	-230		3,426	D
3/31/26 20:17	3/27/26	SLNO	Soleno Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-429	30.44	-14		104	D
3/31/26 18:44	3/30/26	PAHC	Phibro Animal Health Corp	DE	Health	Drug	Pharmaceutical Preparations	1	16	S.dm	-17,919	48.95	-366		140	I
3/31/26 16:27	3/30/26	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	7	S.d	-1,724	28.28	-61		1,522	D
3/31/26 16:25	3/30/26	ASMB	Assembly Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-14	26.69	-1		49	D
3/31/26 16:10	3/30/26	PGEN	Precigen, Inc.	VA	Health	Drug	Pharmaceutical Preparations	1	1	S	-15,750	3.30	-4,773		116,301	I
3/30/26 21:06	3/25/26	IBO	Impact Biomedical Inc.	NV	Health	Drug	Pharmaceutical Preparations	2	2	S.m	-58	0.6088	-95		405	D
3/30/26 21:01	3/17/26	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	7	9	S.dm	-206,252	26.83	-7,687		79,653	D
3/30/26 17:43	3/26/26	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	10	22	S.dm	-16,757	36.65	-457		6,881	I
3/30/26 17:38	3/13/26	NGNE	Neurogene Inc.		Health	Drug	Pharmaceutical Preparations	4	6	S	-494	22.05	-22		1,497	D
3/30/26 17:29	3/26/26	CYPH	Cypherpunk Technologies Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-43	0.7105	-60		130	D
3/27/26 19:36	3/26/26	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	6	12	S.dm	-29,499	90.31	-327		832	D
3/27/26 18:17	3/26/26	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	3	6	S.dm	-11,191	26.75	-418		251	D
3/27/26 17:50	2/23/26	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	11	S.dm	-4,298	16.96	-253		5,968	D
3/27/26 16:57	1/9/26	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	11	S.dm	-8,938	27.74	-322		1,229	I
3/27/26 16:44	3/25/26	TYRA	Tyra Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S.d	-1,020	33.66	-30		183	D
3/27/26 16:27	3/25/26	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	2	5	S.d	-3,553	41.22	-86		2,921	I
3/27/26 16:25	3/25/26	LEGN	Legend Biotech Corp	E9	Health	Drug	Pharmaceutical Preparations	1	1	S	-87	8.77	-10		247	D
3/26/26 20:00	3/25/26	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	5	6	S.dm	-770	21.87	-35		117	D
3/26/26 19:21	3/25/26	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	13	S.dm	-2,756	18.73	-147		754	D
3/26/26 17:00	3/24/26	GNLX	Genelux Corp	DE	Health	Drug	Pharmaceutical Preparations	5	5	S.m	-43	2.72	-16		1,386	D
3/25/26 20:01	3/23/26	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	4	7	S.dm	-471	7.86	-60		1,570	D
3/25/26 16:30	4/14/25	PYXS	Pyxis Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.m	-16	1.03	-15		81	D
3/24/26 19:24	3/23/26	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	1	8	S.dm	-230	2.72	-85	-100	0	D
3/24/26 18:57	3/23/26	OKUR	Onkure Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-2	4.16	0		23	D
3/24/26 18:04	3/23/26	VTRS	Viatris Inc	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-284	13.28	-21		367	D
3/24/26 18:01	3/20/26	ATAI	Ataibeckley Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.d	-355	3.55	-100		8	D
3/23/26 16:05	3/19/26	ALXO	Alx Oncology Holdings Inc	DE	Health	Drug	Pharmaceutical Preparations	2	3	S	-30	2.17	-14		381	D
3/20/26 19:19	3/20/26	EOLS	Evolus, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-80	4.75	-17		1,032	D
3/20/26 17:14	3/18/26	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	2	3	S	-2,736	38.98	-70		163	D
3/20/26 16:05	3/18/26	PVLA	Palvella Therapeutics, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	3	S.d	-1,269	98.34	-13	-100	0	D
3/19/26 20:01	3/18/26	ARVN	Arvinas, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	10	S	-901	12.50	-72		1,820	D
3/19/26 18:41	3/17/26	CTMX	Cytomx Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	S	-1,227	6.42	-191		1,959	D
3/19/26 17:43	3/17/26	PCRX	Pacira Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	S	-438	20.97	-21		427	D
3/19/26 16:01	3/17/26	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	9	19	S.d	-57,251	33.00	-1,735		1,796	D
3/18/26 18:12	3/16/26	TBPH	Theravance Biopharma, Inc.	CA	Health	Drug	Pharmaceutical Preparations	1	1	S	-434	13.96	-31		233	D
3/18/26 17:13	3/16/26	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	6	S	-2,155	37.66	-57		1,740	D
3/18/26 16:42	1/8/26	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	11	S.d	-1,361	6.18	-220		4,093	D
3/18/26 16:13	3/17/26	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	S	-107	2.72	-39		3,566	D
3/18/26 16:12	3/16/26	IRD	Opus Genetics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	S	-181	5.21	-35		2,759	D
3/17/26 20:34	3/17/26	IRWD	Ironwood Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	7	7	S.m	-21,781	3.08	-7,066		12,985	M
3/17/26 19:30	3/16/26	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	21	S.d	-11,984	93.67	-128		499	D
3/17/26 17:11	3/13/26	NATR	Natures Sunshine Products Inc	UT	Health	Drug	Pharmaceutical Preparations	3	3	S	-951	24.45	-39		184	D
3/17/26 17:03	3/16/26	UPB	Upstream Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	5	S	-47	9.29	-5		176	D
3/17/26 16:51	3/12/26	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	11	S.dm	-3,048	30.18	-101		730	D
3/17/26 16:10	3/16/26	ORKA	Oruka Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	8	S.d	-1,072	35.63	-30		1,250	D
3/16/26 18:53	1/8/26	EQ	Equillium, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	5	S.d	-1,328	1.95	-680		191	D
3/16/26 18:05	3/12/26	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	11	S.dm	-27,790	70.67	-393		5,965	I
3/16/26 16:08	3/9/26	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	6	S.dm	-3,837	51.76	-74		2,305	D
3/13/26 20:16	3/13/26	XENE	Xenon Pharmaceuticals Inc.	A1	Health	Drug	Pharmaceutical Preparations	3	6	S.dm	-17,845	60.14	-297		49	D
3/13/26 20:03	3/12/26	SRPT	Sarepta Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-123	17.02	-7		2	D
3/13/26 17:28	3/6/26	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	7	14	S.dm	-4,050	75.44	-54		596	D
3/13/26 17:26	3/11/26	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	1	3	S.d	-903	338.76	-3		318	D
3/12/26 19:55	3/11/26	BMRN	Biomarin Pharmaceutical Inc	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-2,978	60.93	-49		190	D
3/12/26 16:25	3/11/26	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	5	10	S.dm	-46,224	32.44	-1,425		667	D
3/11/26 12:52	3/10/26	AQST	Aquestive Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	7	S.d	-1,651	4.17	-396		2,955	D
3/9/26 19:00	3/5/26	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-642	64.19	-10		237	D
3/9/26 16:07	3/5/26	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	4	7	S.dm	-528	11.35	-47		1,000	D
3/6/26 19:18	3/6/26	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	15	S.d	-28,326	509.35	-56		2,153	D
3/6/26 18:56	3/5/26	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	S.dm	-13,107	40.68	-322		13,556	D
3/6/26 17:29	3/5/26	SDGR	Schrodinger, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	11	S.m	-201	13.08	-15		686	D
3/6/26 17:07	3/4/26	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	6	12	S.d	-2,097	15.13	-139		1,268	D
3/6/26 17:05	3/4/26	ABBV	Abbvie Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S.d	-10,745	232.17	-46		41	D
3/6/26 16:51	3/4/26	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.dm	-2,720	99.75	-27		126	D
3/6/26 16:14	3/4/26	PEPG	Pepgen Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-58	6.23	-9		484	D
3/6/26 16:13	3/4/26	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	5	21	S.dm	-24,039	332.65	-72		248	D
3/5/26 20:00	1/20/26	OLMA	Olema Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	5	S.dm	-7,409	27.72	-267		1,695	D
3/5/26 18:55	3/3/26	ANTX	An2 Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	0	1.06	0	0	67	D
3/5/26 16:05	3/3/26	HROW	Harrow, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	3	S.m	-9,184	41.08	-224		3,885	I
3/4/26 19:54	3/2/26	FOLD	Amicus Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-1,396	14.32	-98		1,021	D
3/4/26 19:00	3/2/26	SEPN	Septerna, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S.d	-2,096	28.15	-74		175	D
3/4/26 18:54	3/2/26	VNDA	Vanda Pharmaceuticals Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	6	S	-2,825	8.20	-344		4,415	D
3/4/26 16:55	3/2/26	IRON	Disc Medicine, Inc.		Health	Drug	Pharmaceutical Preparations	6	9	S.dm	-3,068	63.90	-48		577	D
3/4/26 16:40	2/9/26	KNSA	Kiniksa Pharmaceuticals International, Plc		Health	Drug	Pharmaceutical Preparations	3	5	S.dm	-3,916	44.19	-89		93	D
3/4/26 16:30	3/2/26	ANNX	Annexon, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	10	S	-313	5.25	-60		811	D
3/4/26 16:30	3/2/26	CRBP	Corbus Pharmaceuticals Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	6	S	-248	7.93	-31		419	D
3/4/26 16:00	3/2/26	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	15	S.dm	-5,726	13.75	-416		7,376	D
3/3/26 20:20	3/2/26	ABT	Abbott Laboratories	IL	Health	Drug	Pharmaceutical Preparations	6	6	S	-485	115.58	-4		442	D
3/3/26 17:43	3/2/26	BHC	Bausch Health Companies Inc.	NJ	Health	Drug	Pharmaceutical Preparations	1	2	S.m	-115	5.85	-20		809	D
3/3/26 16:28	3/2/26	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	7	S	-213	9.14	-23		625	D
3/3/26 16:21	2/27/26	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	7	8	S.dm	-80,476	236.78	-340		504	D
3/2/26 19:05	1/30/26	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	S.d	-648	16.56	-39		186	D
3/2/26 16:30	2/23/26	OVID	Ovid Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S.d	-29	1.45	-20		218	D
2/27/26 21:00	2/26/26	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	4	5	S.d	-758	14.46	-52		880	D
2/27/26 19:00	2/25/26	QTTB	Q32 Bio Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-75	4.51	-17		217	D
2/27/26 19:00	2/26/26	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	5	S.d	-19,408	172.84	-112		7,846	D
2/27/26 16:05	2/25/26	CLYM	Climb Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.m	-879	5.86	-150		205	D
2/26/26 16:47	2/24/26	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S.d	-783	13.34	-59		323	D
2/25/26 20:01	2/23/26	VERA	Vera Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	7	S	-1,406	41.98	-33		869	D
2/25/26 18:20	2/23/26	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	6	10	S.m	-1,755	8.90	-197		4,954	D
2/24/26 18:57	2/20/26	MPLT	Maplight Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	5	S.m	-1,368	18.34	-75		397	D
2/24/26 16:58	2/20/26	RIGL	Rigel Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.d	-145	36.36	-4		13	D
2/23/26 18:21	2/23/26	RLYB	Rallybio Corp	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-4	5.06	-1		4	D
2/20/26 19:10	2/18/26	NKTR	Nektar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	2	3	S	-182	40.71	-4		97	D
2/20/26 16:31	2/18/26	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	S	-122	3.32	-37		2,234	D
2/20/26 16:15	2/18/26	KROS	Keros Therapeutics, Inc.		Health	Drug	Pharmaceutical Preparations	4	4	S	-332	16.29	-20		496	D
2/19/26 18:10	2/18/26	GERN	Geron Corp	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.d	-19	1.94	-10		18	D
2/18/26 17:18	2/17/26	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	5	S.d	-423	11.60	-36		2,248	D
2/18/26 17:18	2/13/26	AVDL	Avadel Pharmaceuticals Plc		Health	Drug	Pharmaceutical Preparations	1	1	S	-233,353	21.00	-11,112	-100	0	I
2/18/26 16:30	2/15/26	MCRB	Seres Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	S.d	-4	8.47	-1		36	D
2/17/26 16:22	2/17/26	ZTS	Zoetis Inc.		Health	Drug	Pharmaceutical Preparations	1	1	S.d	-2,541	127.05	-20		102	D
2/13/26 16:37	2/11/26	PBH	Prestige Consumer Healthcare Inc.		Health	Drug	Pharmaceutical Preparations	1	1	S	-66	65.93	-1		41	D
2/13/26 09:23	2/11/26	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	24	S	-2,486	21.51	-116		3,458	D
2/12/26 20:47	2/10/26	LYEL	Lyell Immunopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	7	S.d	-264	23.37	-11		135	D
2/12/26 16:08	2/10/26	SGMT	Sagimet Biosciences Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	S	-105	5.36	-20		988	D
2/12/26 16:02	2/12/26	MRK	Merck & Co., Inc.	NJ	Health	Drug	Pharmaceutical Preparations	9	12	S.d	-40,700	119.56	-340		1,006	D
2/11/26 14:54	2/3/26	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	2	2	S.d	-292	19.69	-15		201	D
2/10/26 21:10	2/6/26	ZNTL	Zentalis Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	3	4	S.m	-135	2.43	-55		299	D
2/10/26 16:49	2/3/26	ZVRA	Zevra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	8	S.d	-1,224	9.21	-133		552	D
2/10/26 09:00	2/9/26	SNDX	Syndax Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.d	-628	20.90	-30		653	D
2/9/26 21:31	2/6/26	SPRO	Spero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.dm	-393	2.29	-172		1,861	D
2/5/26 16:10	2/4/26	VSTM	Verastem, Inc.	MA	Health	Drug	Pharmaceutical Preparations	2	3	S	-116	7.13	-16		718	D
2/4/26 16:15	2/2/26	AKBA	Akebia Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	6	S	-901	1.39	-648		6,528	D
2/4/26 16:15	1/2/26	FULC	Fulcrum Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S	-324	10.80	-30		470	D
2/3/26 16:05	12/10/25	AVBP	Arrivent Biopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-12,983	23.37	-556		3,929	I
1/29/26 19:32	1/28/26	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	1	2	S.m	-102	2.16	-47		1,036	D
1/28/26 20:19	1/26/26	HRMY	Harmony Biosciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S	-892	36.10	-25		25	D
1/28/26 18:30	12/15/25	MIST	Milestone Pharmaceuticals Inc.	A8	Health	Drug	Pharmaceutical Preparations	5	6	S.dm	-1,094	2.25	-487		951	D
1/27/26 21:35	1/27/26	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	6	S	-305	8.46	-36		1,009	D
1/23/26 17:34	1/21/26	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	13	S	-4,226	72.36	-58		887	D
1/22/26 21:46	1/20/26	PLRX	Pliant Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	S	-164	1.28	-128		1,295	D
1/22/26 21:30	1/21/26	CRMD	Cormedix Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-69	6.88	-10		38	D
1/22/26 13:04	12/12/25	OGEN	Oragenics Inc	FL	Health	Drug	Pharmaceutical Preparations	1	1	S.ad	0	0.9429	0		1	D
1/21/26 12:46	1/21/26	XCUR	Exicure, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	3	S	-7,805	4.50	-1,734		5,925	D
1/20/26 17:39	1/15/26	NKTX	Nkarta, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-66	2.07	-32		558	D
1/20/26 16:33	1/15/26	DVAX	Dynavax Technologies Corp	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.d	-1,783	15.64	-114		63	D
1/20/26 16:07	1/16/26	HOWL	Werewolf Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	3	S.m	-136	0.5645	-241		2,310	I
1/14/26 17:25	1/12/26	OMER	Omeros Corp	WA	Health	Drug	Pharmaceutical Preparations	1	1	S.dm	-751	12.52	-60	-100	0	D
1/13/26 17:11	1/12/26	ZYME	Zymeworks Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	S.d	-1,256	22.67	-55		435	D
1/9/26 20:30	1/8/26	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-298	6.33	-47		985	D
1/8/26 20:27	1/6/26	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S.m	-322	5.86	-55		7,495	D
1/8/26 16:20	1/6/26	RNAC	Cartesian Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S	-259	6.82	-38		504	D
1/8/26 16:05	11/25/25	CVRX	Cvrx, Inc.	NJ	Health	Drug	Pharmaceutical Preparations	1	1	S.am	-224	10.03	-22		4,025	I
1/8/26 16:00	1/7/26	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	1	1	S.e	-33	0.1131	-292	0	91,897	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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