Insider Stock Trading

Filing Date	T Date	Ticker	Issuer	Inc	Sector	Ind	Industry	#o	#f	T	TVal	Price	Qty	oc	Own	H
8/25/25 21:33	8/22/25	KALV	Kalvista Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	41	S.d	-3,643	12.43	-293		739	D
8/25/25 21:13	8/21/25	ARDX	Ardelyx, Inc.	DE	Health	Drug	Pharmaceutical Preparations	10	70	S.dm	-12,260	6.83	-1,794		4,928	D
8/25/25 20:59	8/21/25	RYTM	Rhythm Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	11	56	S.dm	-43,543	61.62	-707		420	D
8/25/25 19:46	8/21/25	BYSI	Beyondspring Inc.		Health	Drug	Pharmaceutical Preparations	1	4	S.m	-1,333	2.90	-460		4,488	I
8/25/25 19:12	8/30/24	JNJ	Johnson & Johnson	NJ	Health	Drug	Pharmaceutical Preparations	5	7	S.d	-32,811	174.68	-188		540	D
8/25/25 17:04	8/21/25	NAMS	Newamsterdam Pharma Co N.V.	P7	Health	Drug	Pharmaceutical Preparations	6	23	S.dm	-40,282	17.07	-2,360		12,377	I
8/25/25 16:27	8/22/25	AMRX	Amneal Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	9	29	S.dm	-62,518	8.49	-7,366		52,475	D
8/25/25 16:19	8/22/25	ANIP	Ani Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	15	57	S.dm	-57,828	76.17	-759		2,339	D
8/22/25 21:00	6/18/25	ROIV	Roivant Sciences Ltd.	D0	Health	Drug	Pharmaceutical Preparations	8	25	S.dm	-183,914	11.53	-15,944		186,300	D
8/22/25 20:49	3/24/25	DVAX	Dynavax Technologies Corp	DE	Health	Drug	Pharmaceutical Preparations	3	5	S.dm	-23,197	10.91	-2,126		15,785	D
8/22/25 19:07	11/15/24	SKYE	Skye Bioscience, Inc.	NV	Health	Drug	Pharmaceutical Preparations	6	9	S.m	-6,478	5.10	-1,271		20,675	D
8/22/25 17:20	8/22/25	RNA	Avidity Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	11	66	S.dm	-79,552	39.49	-2,015		1,872	D
8/22/25 16:58	8/21/25	BBIO	Bridgebio Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	11	32	S.dm	-336,195	39.57	-8,496		31,744	D
8/22/25 16:32	8/21/25	UTHR	United Therapeutics Corp	DE	Health	Drug	Pharmaceutical Preparations	13	132	S.dm	-331,191	319.53	-1,036		783	D
8/22/25 16:30	8/21/25	SPRY	Ars Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	12	67	S.dm	-110,349	13.56	-8,138		55,785	I
8/22/25 16:19	8/21/25	BHC	Bausch Health Companies Inc.	NJ	Health	Drug	Pharmaceutical Preparations	2	3	S	-209	7.02	-30		509	D
8/22/25 16:07	8/21/25	LYEL	Lyell Immunopharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	8	S.m	-134	10.53	-13		124	D
8/21/25 21:32	5/28/25	ARQT	Arcutis Biotherapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	9	61	S.dm	-8,225	11.74	-701		2,422	D
8/21/25 21:05	8/19/25	NKTR	Nektar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	5	23	S.dm	-620	1.27	-489		20,379	D
8/21/25 20:44	8/21/25	CLNN	Clene Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	11	S.m	-62	0.9194	-67	0	15,428	D
8/21/25 18:48	8/20/25	ELVN	Enliven Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	9	100	S.dm	-65,605	22.55	-2,909		18,353	I
8/21/25 17:44	8/18/25	MDGL	Madrigal Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	11	38	S.dm	-155,904	340.40	-458		2,610	D
8/21/25 17:07	8/4/25	INSM	Insmed Inc	VA	Health	Drug	Pharmaceutical Preparations	9	90	S.dm	-188,168	74.66	-2,520		2,003	D
8/21/25 17:00	8/19/25	CYRX	Cryoport, Inc.	NV	Health	Drug	Pharmaceutical Preparations	7	28	S.dm	-5,316	6.88	-773		1,536	D
8/21/25 16:30	8/19/25	LQDA	Liquidia Corp	DE	Health	Drug	Pharmaceutical Preparations	10	82	S.d	-7,608	13.57	-561		18,708	D
8/21/25 16:30	8/20/25	CRNX	Crinetics Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	32	S.d	-23,005	44.97	-512		1,630	D
8/21/25 16:15	8/19/25	TNGX	Tango Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	9	24	S.dm	-64,624	5.69	-11,367		46,194	D
8/21/25 16:05	8/20/25	SION	Sionna Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S.dm	-1,693	21.99	-77		619	D
8/20/25 18:14	8/18/25	IONS	Ionis Pharmaceuticals Inc	CA	Health	Drug	Pharmaceutical Preparations	16	48	S.adm	-12,390	38.76	-320		1,038	D
8/20/25 17:14	8/19/25	ETON	Eton Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S.m	-4,771	16.70	-286		3,691	D
8/20/25 17:13	8/18/25	SER	Serina Therapeutics, Inc.	AL	Health	Drug	Pharmaceutical Preparations	1	9	S.dm	-287	5.52	-52	-100	0	D
8/20/25 17:00	8/18/25	RCKT	Rocket Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	9	45	S.dm	-11,885	22.53	-527		3,531	D
8/20/25 16:57	8/18/25	COLL	Collegium Pharmaceutical, Inc	VA	Health	Drug	Pharmaceutical Preparations	8	23	S.dm	-15,569	32.64	-477		3,905	D
8/20/25 16:36	8/18/25	KNSA	Kiniksa Pharmaceuticals International, Plc	X0	Health	Drug	Pharmaceutical Preparations	8	46	S.dm	-43,993	27.40	-1,606		563	D
8/20/25 16:13	8/18/25	STOK	Stoke Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	33	S.dm	-127,151	11.69	-10,879		11,093	D
8/19/25 20:00	8/15/25	WVE	Wave Life Sciences Ltd.	U0	Health	Drug	Pharmaceutical Preparations	7	14	S.d	-8,966	11.98	-748		6,448	D
8/19/25 19:40	8/18/25	DAWN	Day One Biopharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	35	S.dm	-6,498	14.47	-449		4,360	D
8/19/25 18:00	8/18/25	ACAD	Acadia Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	6	24	S.d	-2,865	18.15	-158		368	D
8/19/25 17:28	8/18/25	ALNY	Alnylam Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	11	47	S.dm	-114,269	288.12	-397		557	D
8/19/25 16:40	8/18/25	APLS	Apellis Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	12	55	S.dm	-12,790	29.66	-431		4,394	D
8/19/25 16:40	8/18/25	ZLAB	Zai Lab Ltd	E9	Health	Drug	Pharmaceutical Preparations	10	49	S.dm	-27,529	31.44	-876		1,559	D
8/19/25 16:37	8/19/25	CYTK	Cytokinetics Inc		Health	Drug	Pharmaceutical Preparations	10	94	S.d	-29,418	47.90	-614		849	D
8/19/25 16:30	8/7/25	NUVL	Nuvalent, Inc.	DE	Health	Drug	Pharmaceutical Preparations	10	73	S.dm	-375,056	90.52	-4,144		21,831	D
8/19/25 16:15	8/15/25	HRMY	Harmony Biosciences Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	16	S.dm	-286,486	30.48	-9,400		12,669	D
8/19/25 16:12	2/19/25	ALXO	Alx Oncology Holdings Inc	DE	Health	Drug	Pharmaceutical Preparations	4	22	S.d	-1,688	10.04	-168		1,241	D
8/19/25 16:08	8/18/25	MCRB	Seres Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	36	S.d	-93	0.9407	-98		634	D
8/18/25 17:14	8/15/25	RAPP	Rapport Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	6	S	-595	11.66	-51		469	D
8/18/25 17:02	8/14/25	SNDX	Syndax Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	4	7	S.dm	-1,411	14.71	-96		669	D
8/18/25 16:33	8/15/25	EBS	Emergent Biosolutions Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	10	S	-961	8.01	-120		451	D
8/18/25 16:31	8/14/25	SUPN	Supernus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	15	S.dm	-19,483	38.10	-511		2,295	D
8/15/25 19:23	8/13/25	IRON	Disc Medicine, Inc.	DE	Health	Drug	Pharmaceutical Preparations	10	43	S.dm	-55,657	55.47	-1,003		1,984	I
8/15/25 18:13	8/15/25	CNTA	Centessa Pharmaceuticals Plc	X0	Health	Drug	Pharmaceutical Preparations	7	48	S.dm	-22,406	15.82	-1,417		1,877	D
8/15/25 17:59	8/13/25	ARWR	Arrowhead Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	9	17	S.dm	-11,934	16.92	-705		5,676	D
8/15/25 16:57	8/13/25	XERS	Xeris Biopharma Holdings, Inc.		Health	Drug	Pharmaceutical Preparations	3	3	S	-1,313	6.91	-190		2,307	D
8/15/25 16:40	8/1/25	ONC	Beone Medicines Ltd.		Health	Drug	Pharmaceutical Preparations	10	63	S.dm	-2,775,531	134.56	-20,626		202,726	D
8/15/25 16:30	8/14/25	ABEO	Abeona Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	20	S	-2,043	5.85	-349		2,765	D
8/15/25 12:45	8/13/25	NATR	Natures Sunshine Products Inc	UT	Health	Drug	Pharmaceutical Preparations	4	6	S.m	-33,184	11.50	-2,886		3,118	D
8/14/25 19:43	8/12/25	EWTX	Edgewise Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	31	S.dm	-15,081	27.27	-553		561	D
8/14/25 18:02	8/13/25	MLYS	Mineralys Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	25	S.dm	-14,859	13.26	-1,121		10,017	D
8/14/25 17:00	8/12/25	ABBV	Abbvie Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	13	S.dm	-130,988	191.03	-686		899	D
8/14/25 16:20	8/12/25	AMLX	Amylyx Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	21	S.m	-944	4.00	-236		7,410	D
8/14/25 16:15	8/13/25	DSGN	Design Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S	-6,441	4.66	-1,381		4,238	I
8/13/25 18:37	8/12/25	AKRO	Akero Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	97	S.dm	-58,108	38.63	-1,504		1,457	D
8/13/25 18:03	4/3/25	ALDX	Aldeyra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	S.a	-5,150	1.48	-3,474		6,259	I
8/13/25 16:05	8/11/25	IRWD	Ironwood Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	10	21	S.m	-2,031	3.84	-528		4,141	D
8/13/25 09:58	8/11/25	URGN	Urogen Pharma Ltd.	L3	Health	Drug	Pharmaceutical Preparations	2	9	S.d	-689	14.57	-47		200	D
8/12/25 20:00	8/11/25	MIRM	Mirum Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	27	S.dm	-15,819	46.55	-340		523	D
8/12/25 19:22	8/11/25	CORT	Corcept Therapeutics Inc	DE	Health	Drug	Pharmaceutical Preparations	7	72	S.dm	-76,474	72.03	-1,062		4,464	D
8/12/25 16:24	8/8/25	AGIO	Agios Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	9	28	S.dm	-7,266	40.84	-178		454	D
8/12/25 16:16	7/24/25	LLY	Eli Lilly & Co	IN	Health	Drug	Pharmaceutical Preparations	5	44	S.ed	-2,763,646	868.86	-3,181		98,989	D
8/12/25 16:02	8/8/25	ANAB	Anaptysbio, Inc	DE	Health	Drug	Pharmaceutical Preparations	5	15	S.dm	-2,778	29.39	-95		33	D
8/11/25 17:53	8/8/25	ABT	Abbott Laboratories	IL	Health	Drug	Pharmaceutical Preparations	12	17	S.dm	-117,434	125.31	-937		1,457	D
8/11/25 16:35	8/11/25	RPRX	Royalty Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	1	1	S.d	-1,214	36.23	-34		195	D
8/11/25 16:09	8/7/25	PCRX	Pacira Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	13	S.d	-1,293	26.48	-49		460	D
8/7/25 16:15	8/5/25	AIMD	Ainos, Inc.	TX	Health	Drug	Pharmaceutical Preparations	3	6	S.m	-149	1.24	-120		8,301	D
8/6/25 20:38	8/6/25	VSTM	Verastem, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	36	S.dm	-789	6.83	-115		721	D
8/5/25 20:32	8/1/25	VRNA	Verona Pharma Plc	X0	Health	Drug	Pharmaceutical Preparations	13	52	S.dm	-68,994	6.75	-10,215		35,988	D
8/5/25 17:58	8/2/25	BMY	Bristol Myers Squibb Co	DE	Health	Drug	Pharmaceutical Preparations	3	3	S.d	-59	50.51	-1		26	D
8/5/25 17:03	8/1/25	LGND	Ligand Pharmaceuticals Inc	DE	Health	Drug	Pharmaceutical Preparations	6	18	S.dm	-10,982	97.48	-113		227	D
8/5/25 16:54	2/3/25	JAZZ	Jazz Pharmaceuticals Plc	L2	Health	Drug	Pharmaceutical Preparations	5	20	S.dm	-6,360	130.24	-49		622	D
8/5/25 16:07	8/1/25	AUPH	Aurinia Pharmaceuticals Inc.		Health	Drug	Pharmaceutical Preparations	13	15	S.dm	-6,462	7.91	-816		4,322	D
8/5/25 16:04	8/1/25	TEVA	Teva Pharmaceutical Industries Ltd	L3	Health	Drug	Pharmaceutical Preparations	13	26	S.dm	-38,455	17.51	-2,196		2,200	D
8/4/25 19:23	7/30/25	CYCC	Cyclacel Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-5,591	0.0287	-194,636	-100	156	D
8/4/25 19:17	8/1/25	AMPH	Amphastar Pharmaceuticals, Inc.		Health	Drug	Pharmaceutical Preparations	5	22	S.dm	-4,538	44.38	-102		512	D
8/1/25 17:09	8/1/25	NRIX	Nurix Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	41	S.d	-3,850	19.83	-194		185	D
8/1/25 16:30	7/30/25	ALZN	Alzamend Neuro, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	4	S.dm	-634	2.59	-245		96	I
7/30/25 16:56	7/29/25	KPTI	Karyopharm Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	30	S.m	-1,893	1.04	-1,821		2,917	D
7/29/25 16:52	7/25/25	CALC	Calcimedica, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-4	3.65	-1		13	M
7/28/25 18:08	7/25/25	PTGX	Protagonist Therapeutics, Inc	DE	Health	Drug	Pharmaceutical Preparations	5	20	S.dm	-22,905	46.99	-487		968	D
7/25/25 19:06	7/23/25	IGMS	Igm Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	32	S.d	-537	5.43	-99		1,500	D
7/23/25 18:09	7/22/25	HOOK	Hookipa Pharma Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-39	0.9200	-43		136	D
7/23/25 17:00	7/22/25	MURA	Mural Oncology Plc	L2	Health	Drug	Pharmaceutical Preparations	4	12	S.dm	-221	3.16	-70		519	D
7/23/25 16:16	7/21/25	SGMT	Sagimet Biosciences Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	7	S	-950	6.72	-141		1,123	D
7/22/25 19:51	7/18/25	PBYI	Puma Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	11	28	S.m	-1,464	3.39	-432		8,082	D
7/18/25 16:07	7/17/25	ESPR	Esperion Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	27	S	-176	1.64	-108		3,099	D
7/18/25 16:05	7/17/25	MRUS	Merus N.V.	P7	Health	Drug	Pharmaceutical Preparations	2	9	S.dm	-9,947	55.95	-178		11	D
7/18/25 16:05	7/16/25	PHAT	Phathom Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	11	S	-885	9.42	-94		1,566	D
7/17/25 20:51	7/16/25	MNKD	Mannkind Corp	DE	Health	Drug	Pharmaceutical Preparations	4	21	S.d	-4,055	5.58	-727		5,348	D
7/17/25 18:20	7/15/25	ETNB	89Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	4	S	-505	7.80	-65		343	D
7/16/25 21:06	7/14/25	MNPR	Monopar Therapeutics	DE	Health	Drug	Pharmaceutical Preparations	4	4	S.d	-2,867	37.80	-76		1,745	D
7/16/25 18:01	7/14/25	TBPH	Theravance Biopharma, Inc.	E9	Health	Drug	Pharmaceutical Preparations	1	6	S	-522	10.44	-50		370	D
7/16/25 16:20	7/14/25	ANNX	Annexon, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	20	S.d	-322	4.27	-75		826	D
7/11/25 17:27	3/17/25	TRDA	Entrada Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	8	24	S.dm	-6,055	11.80	-513		18,096	D
7/10/25 16:17	7/8/25	ELTP	Elite Pharmaceuticals Inc /Nv/	NJ	Health	Drug	Pharmaceutical Preparations	1	2	S.m	-678	0.5084	-1,334		2,300	D
7/8/25 17:55	7/7/25	BRFG	Bullfrog Ai Holdings, Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	10	S.m	-471	1.89	-250		2,522	D
7/8/25 16:20	7/3/25	BPMC	Blueprint Medicines Corp	DE	Health	Drug	Pharmaceutical Preparations	12	50	S.dm	-39,835	98.35	-405		814	D
7/8/25 16:00	7/3/25	GLTO	Galecto, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	S.d	-15	4.81	-3		6	D
7/7/25 17:20	7/2/25	BCYC	Bicycle Therapeutics Plc	X0	Health	Drug	Pharmaceutical Preparations	9	35	S.dm	-1,161	14.46	-80		1,038	D
7/7/25 16:03	7/3/25	MLTX	Moonlake Immunotherapeutics	E9	Health	Drug	Pharmaceutical Preparations	2	2	S.d	-10,333	53.12	-195		172	D
7/3/25 19:51	7/1/25	PMVP	Pmv Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	6	S	-167	1.09	-153		1,212	D
7/3/25 19:39	7/1/25	LFVN	Lifevantage Corp		Health	Drug	Pharmaceutical Preparations	4	4	S.d	-401	19.07	-21		408	D
7/3/25 16:15	7/2/25	KZR	Kezar Life Sciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S	-7	0.9863	-8		36	D
7/3/25 15:31	5/3/24	VKTX	Viking Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	22	S.d	-88,009	63.96	-1,376		3,010	D
7/3/25 14:55	7/1/25	TERN	Terns Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	11	S.dm	-1,884	9.07	-208		1,687	D
7/3/25 13:28	7/1/25	RMTI	Rockwell Medical, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	14	S	-118	1.72	-68		716	D
7/2/25 17:28	7/1/25	TVTX	Travere Therapeutics, Inc.	CA	Health	Drug	Pharmaceutical Preparations	10	42	S.dm	-7,579	19.01	-399		1,158	D
7/2/25 16:15	6/30/25	PMN	Promis Neurosciences Inc.	Z4	Health	Drug	Pharmaceutical Preparations	1	1	S	0	0.00	-93		2,124	D
7/2/25 16:07	7/1/25	ORIC	Oric Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	8	S.dm	-968	9.46	-102		932	D
7/1/25 21:23	6/27/25	CRVS	Corvus Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S.d	-9,784	4.16	-2,353		14,330	I
7/1/25 17:01	6/30/25	AKBA	Akebia Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	12	S.d	-1,036	2.17	-478		6,290	D
7/1/25 16:49	6/27/25	QURE	Uniqure N.V.		Health	Drug	Pharmaceutical Preparations	13	30	S.dm	-3,049	11.95	-255		1,522	D
7/1/25 16:37	7/19/24	CLYM	Climb Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	13	S.dm	-3,496	6.88	-508		530	D
6/30/25 17:02	6/26/25	ZVRA	Zevra Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	5	S.m	-1,141	8.13	-140		331	D
6/26/25 20:00	6/24/25	KALA	Kala Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	26	S.d	-597	4.77	-125		597	D
6/25/25 18:52	6/23/25	OKUR	Onkure Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	6	S.m	-3,424	1.86	-1,842		1,830	D
6/24/25 16:08	6/24/25	ARVN	Arvinas, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	8	S.m	-913	14.44	-63		1,764	D
6/23/25 19:42	6/20/25	AXSM	Axsome Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	11	S.dm	-20,104	98.38	-204		517	D
6/23/25 13:50	6/20/25	RARE	Ultragenyx Pharmaceutical Inc.	DE	Health	Drug	Pharmaceutical Preparations	9	22	S.dm	-10,915	44.57	-245		3,588	D
6/20/25 17:42	6/17/25	TYRA	Tyra Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	15	S.m	-9,029	18.79	-480		10,040	D
6/20/25 16:08	6/18/25	NKTX	Nkarta, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	12	S	-158	2.74	-58		1,036	D
6/18/25 17:12	6/16/25	BCAX	Bicara Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-1,186	12.49	-95	-100	0	D
6/17/25 16:11	6/13/25	CTMX	Cytomx Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	13	S.dm	-303	1.59	-190		2,075	D
6/16/25 21:10	6/13/25	VNDA	Vanda Pharmaceuticals Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	3	S	-71	5.00	-14		326	D
6/16/25 19:35	6/16/25	XNCR	Xencor Inc	DE	Health	Drug	Pharmaceutical Preparations	11	23	S.dm	-5,082	20.16	-252		989	D
6/16/25 17:47	6/13/25	TGTX	Tg Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	6	S.m	-2,828	26.36	-107		1,202	D
6/16/25 16:42	6/13/25	EOLS	Evolus, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	22	S.dm	-10,870	12.35	-880		1,632	D
6/16/25 15:40	8/9/24	ANTX	An2 Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	7	S.m	-6,921	1.10	-6,275		3,731	I
6/13/25 19:57	6/13/25	LTRN	Lantern Pharma Inc.	TX	Health	Drug	Pharmaceutical Preparations	2	7	S.m	-1,190	3.44	-346		2,411	I
6/12/25 17:00	6/10/25	CPRX	Catalyst Pharmaceuticals, Inc.	DE	Health	Drug	Pharmaceutical Preparations	9	24	S.dm	-48,948	22.22	-2,203		6,066	D
6/11/25 16:15	6/9/25	HROW	Harrow, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	9	S.m	-2,908	30.61	-95		3,960	I
6/10/25 16:39	6/9/25	ALKS	Alkermes Plc.		Health	Drug	Pharmaceutical Preparations	4	13	S.dm	-20,553	32.83	-626		216	D
6/6/25 17:58	6/5/25	XENE	Xenon Pharmaceuticals Inc.	A1	Health	Drug	Pharmaceutical Preparations	4	4	S.dm	-3,186	40.53	-79		81	D
6/6/25 16:47	6/5/25	KRON	Kronos Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-22	0.8678	-25		139	D
6/6/25 16:07	11/14/24	DYN	Dyne Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	11	67	S.dm	-120,223	39.70	-3,029		9,645	I
6/5/25 19:25	3/26/25	NTHI	Neonc Technologies Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	10	S.ad	-7,648	24.85	-308		15,023	M
6/4/25 16:31	6/3/25	ZTS	Zoetis Inc.		Health	Drug	Pharmaceutical Preparations	4	7	S.d	-1,240	169.89	-7		127	D
6/3/25 18:34	5/29/25	CKPT	Checkpoint Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	9	S.dm	-4,804	3.56	-1,350		5,234	D
6/3/25 16:20	6/2/25	OCUL	Ocular Therapeutix, Inc	DE	Health	Drug	Pharmaceutical Preparations	6	18	S.m	-1,257	7.63	-165		4,686	D
6/2/25 18:00	5/29/25	LGVN	Longeveron Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	4	S.m	-39	1.33	-30		976	D
6/2/25 16:30	5/30/25	CRBP	Corbus Pharmaceuticals Holdings, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	7	S.dm	-3,975	39.01	-102		293	D
5/29/25 16:01	5/27/25	GYRE	Gyre Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	41	S.dm	-1,881	11.71	-161		2,941	I
5/28/25 20:06	5/23/25	LFCR	Lifecore Biomedical, Inc. De	DE	Health	Drug	Pharmaceutical Preparations	1	4	S.m	-9,871	6.62	-1,491		1,714	I
5/21/25 19:11	5/20/25	XOMA	Xoma Royalty Corp		Health	Drug	Pharmaceutical Preparations	2	4	S.d	-1,865	27.51	-68		98	D
5/21/25 12:57	5/20/25	MDCX	Medicus Pharma Ltd.	A6	Health	Drug	Pharmaceutical Preparations	1	1	S	-579	7.72	-75		3,249	I
5/20/25 17:58	5/20/25	BMRN	Biomarin Pharmaceutical Inc	DE	Health	Drug	Pharmaceutical Preparations	7	14	S.dm	-12,322	80.69	-153		1,055	D
5/19/25 18:30	5/19/25	KURA	Kura Oncology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	11	S	-446	8.63	-52		412	D
5/19/25 17:07	5/15/25	VRTX	Vertex Pharmaceuticals Inc / Ma	MA	Health	Drug	Pharmaceutical Preparations	13	51	S.dm	-76,651	482.28	-159		541	D
5/15/25 16:43	5/14/25	NGNE	Neurogene Inc.		Health	Drug	Pharmaceutical Preparations	2	2	S	-179	15.87	-11		93	D
5/14/25 21:55	5/12/25	KTTA	Pasithea Therapeutics Corp.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S	-1	0.8250	-1		40	D
5/13/25 17:05	5/12/25	GNLX	Genelux Corp	DE	Health	Drug	Pharmaceutical Preparations	9	24	S.m	-2,211	2.61	-846		4,592	D
5/9/25 21:30	5/7/25	OSTX	Os Therapies Inc	DE	Health	Drug	Pharmaceutical Preparations	1	4	S.m	-642	2.48	-259		2,770	I
5/9/25 16:15	5/8/25	FULC	Fulcrum Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	2	S	-4	5.93	-1		14	D
5/6/25 19:06	5/2/25	PRTA	Prothena Corp Public Ltd Co	L2	Health	Drug	Pharmaceutical Preparations	1	1	S.m	-50,840	8.10	-6,280		5,305	I
5/6/25 16:05	5/2/25	NUVB	Nuvation Bio Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S.d	-213	2.79	-76		6,125	D
5/5/25 17:34	5/2/25	DERM	Journey Medical Corp	DE	Health	Drug	Pharmaceutical Preparations	3	9	S.m	-960	5.19	-185		3,057	D
5/2/25 20:00	5/1/25	JANX	Janux Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	21	S.dm	-342,935	51.17	-6,702		21,664	D
5/1/25 19:07	4/30/25	ACRV	Acrivon Therapeutics, Inc.		Health	Drug	Pharmaceutical Preparations	1	2	S.m	-3,763	1.67	-2,257		3,841	I
4/30/25 16:17	3/27/25	HOWL	Werewolf Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	3	S.d	-9	1.05	-9	0	14,237	I
4/29/25 16:04	4/25/25	MRK	Merck & Co., Inc.	NJ	Health	Drug	Pharmaceutical Preparations	4	4	S.d	-1,789	84.70	-21		70	D
4/15/25 17:30	3/31/25	ASMB	Assembly Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	15	S.d	-124	13.32	-9		53	D
4/15/25 16:31	4/14/25	SDGR	Schrodinger, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	9	S.d	-787	24.42	-32		144	D
4/7/25 17:18	4/3/25	IBO	Impact Biomedical Inc.	NV	Health	Drug	Pharmaceutical Preparations	1	1	S	-174	0.4950	-352	-100	0	I
4/3/25 17:00	4/2/25	VERV	Verve Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	7	S.d	-103	4.18	-25		1,099	D
4/3/25 16:30	4/2/25	SYBX	Synlogic, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	3	S	-3	1.32	-2		15	D
4/3/25 16:27	4/2/25	INZY	Inozyme Pharma, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.d	-8	0.8900	-9		41	D
4/3/25 16:21	4/2/25	VTYX	Ventyx Biosciences, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	3	S.d	-82	2.25	-36		486	D
4/3/25 16:17	4/2/25	UBX	Unity Biotechnology, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	17	S.d	-151	1.05	-143		319	D
3/26/25 16:30	3/25/25	TRVI	Trevi Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	12	S.dm	-1,171	4.04	-290		917	D
3/24/25 21:00	3/21/25	ATAI	Atai Life Sciences N.V.	P7	Health	Drug	Pharmaceutical Preparations	6	6	S	-537	1.61	-334		854	D
3/19/25 18:11	3/17/25	SLRN	Acelyrin, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	4	S	-69	2.74	-25		918	D
3/19/25 16:49	3/17/25	TSVT	2Seventy Bio, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	18	S.m	-80,541	4.91	-16,393		3,133	D
3/19/25 15:31	3/18/25	NIKA	Nika Pharmaceuticals, Inc	CO	Health	Drug	Pharmaceutical Preparations	1	1	S	-500	0.2500	-2,000	0	455,590	D
3/19/25 14:48	3/18/25	OPTN	Optinose, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	16	S	-287	1.31	-220		2,270	D
3/18/25 18:45	3/17/25	VRCA	Verrica Pharmaceuticals Inc.	DE	Health	Drug	Pharmaceutical Preparations	5	10	S.dm	-1,080	4.33	-249		686	D
3/14/25 16:30	3/12/25	RPTX	Repare Therapeutics Inc.	Z4	Health	Drug	Pharmaceutical Preparations	4	4	S	-42	1.14	-37		595	D
3/13/25 20:00	3/12/25	SRPT	Sarepta Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	7	7	S.dm	-11,309	150.87	-75		143	D
3/12/25 16:01	3/10/25	PBH	Prestige Consumer Healthcare Inc.		Health	Drug	Pharmaceutical Preparations	5	9	S.d	-13,650	82.83	-165		408	D
3/11/25 20:17	3/7/25	YMAB	Y-Mabs Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	6	9	S.dm	-4,152	12.67	-328		913	D
3/10/25 20:07	3/10/25	PRGO	Perrigo Co Plc	L2	Health	Drug	Pharmaceutical Preparations	4	5	S.d	-2,307	28.02	-82		126	D
3/6/25 21:30	3/4/25	INVA	Innoviva, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.m	-28,395	17.55	-1,618		5,659	I
3/6/25 21:08	3/4/25	ORGO	Organogenesis Holdings Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	4	S.dm	-1,486	3.67	-405		3,527	D
3/6/25 20:30	3/4/25	APLT	Applied Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	12	S.m	-5,453	5.07	-1,076		9,773	D
3/6/25 13:57	3/4/25	PFE	Pfizer Inc	DE	Health	Drug	Pharmaceutical Preparations	1	2	S.d	-213	27.77	-8		12	D
3/4/25 18:09	3/3/25	AADI	Aadi Bioscience, Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	9	S.dm	-375	1.70	-220		2,231	D
3/4/25 16:59	2/28/25	CARA	Cara Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	6	S	-11	0.8367	-13		184	D
2/28/25 16:15	2/26/25	OVID	Ovid Therapeutics Inc.	DE	Health	Drug	Pharmaceutical Preparations	2	2	S	-5	0.5600	-9		141	D
2/27/25 16:05	2/21/25	VERA	Vera Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	3	17	S.dm	-13,558	41.80	-324		630	D
2/26/25 20:24	2/26/25	PEPG	Pepgen Inc.	DE	Health	Drug	Pharmaceutical Preparations	4	10	S.dm	-1,045	16.59	-63		3	D
2/21/25 19:27	2/19/25	FOLD	Amicus Therapeutics, Inc.	DE	Health	Drug	Pharmaceutical Preparations	1	11	S.d	-734	10.75	-68		1,151	D
2/19/25 16:23	2/15/25	MGNX	Macrogenics Inc	DE	Health	Drug	Pharmaceutical Preparations	1	1	S.d	-1	2.56	0		10	D

D	Derivative transaction in filing (usually option exercise)
M	Multiple transactions in filing; earliest reported transaction date and weighted average transaction price
A	Amended filing
E	Error detected in filing

S - Sale	Sale of securities on an exchange or to another person
S - Sale+OE	Sale of securities on an exchange or to another person (after option exercise)
F - Tax	Payment of exercise price or tax liability using portion of securities received from the company
P - Purchase	Purchase of securities on an exchange or from another person

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